Rhonda Patrick on Diet-Gene Interactions, Epigenetics, the Vitamin D-Serotonin Link and DNA Damage Fundraiser

Rhonda Patrick on Diet-Gene Interactions, Epigenetics, the Vitamin D-Serotonin Link and DNA Damage Fundraiser 280,385 viewsFeb 3, 2016 TheIHMC 71.5K subscribers Our genes influence the way we absorb and metabolize micronutrients. Nutrigenomics looks at the influence genetic variation has over micronutrient absorption/metabolism and the biological consequences of this dynamic relationship. Our diet also influences which of these genes are turned on or off! Emerging evidence in the field of epigenetics has demonstrated that not only can we change the expression of our own genes within our own lifetime; sometimes these changes are heritable and affect our children and grandchildren. In this talk we’ll be exploring the intersection between genetics, nutrition, and environment: how your diet, micronutrients, exercise, heat stress, and sleep can change the expression of your genes and how this has profound effects on the way your body functions and ages. Rhonda Perciavalle Patrick, Ph.D. is an assistant scientist at Children’s Hospital Oakland Research Institute working with Dr. Bruce Ames. She investigates the effects of micronutrient (vitamins and minerals) deficiencies on metabolism, inflammation, DNA damage, and aging in people. She also researches the role of vitamin D in brain function and dysfunction. In addition to Rhonda’s active role as a researcher, she also functions as a science communicator for a broad lay audience via her web and video presence found at FoundMyFitness.com. She is passionate about disseminating health-related information in a way that the general public can easily understand. She is a frequent speaker and writer on topics ranging from general health and wellness, to diet and aging, to vitamins and their effects. It is Rhonda’s goal to challenge the status quo and encourage the wider public to think about health and longevity using a proactive, preventative approach. Rhonda earned her Ph.D. in biomedical science from the University of Tennessee and performed her graduate research work at St. Jude Children’s Research Hospital. She also has a Bachelor’s of Science degree in biochemistry/chemistry from the University of California, San Diego. She has done extensive research on aging, cancer and nutrition, and metabolism. Chapters Diet-Gene Interactions, Epigenetics, the Vitamin D-Serotonin Link and DNA Damage 0:17 Micronutrients are Cofactors for Enzymes 1:32 Over 300 Enzymes Require Magnesium 2:44 TRPM6 polymorphisms 5:22 Simple Solution: Eat Your Greens! 5:43 Heterocyclic Amines 8:16 348 Comments rongmaw lin Add a comment... John Smith John Smith 3 years ago (edited) I would like to complement the producer of this video. It is by far the best formatted lecture presentation I have ever seen on You Tube. The way you (I assume TheIHMC?) set it up, placing the presenter full size on the right of the screen, including full size, and clear, slides on the left, was phenomenal. This technique avoids the distractions of poor presenter coverage, and difficult to read slides, distracting from the content that the presenter is trying to share with the audience. We done, well done indeed! By the way, I'm also a big fan of Dr. Patrick. 140 Lindy Ford Nutrition & Wellness Lindy Ford Nutrition & Wellness 4 years ago Dr. Patrick speaks with authority. I'm constantly on my patients about "eating their greens." Thank you for sharing this. 26 Kieran Doherty Kieran Doherty 4 years ago I'm a pre PA student who is currently taking genetics and this is awesome! Thanks for all the educating you do Rhonda! 13 Jason Dames Jason Dames 6 years ago I love this stuff!! so informative and has a lot of substance unlike most health practitioners!! Thank you Rhonda! 43 Angelica Brito Angelica Brito 3 years ago My health Guru. Even when I have to watch her videos more than one time to understand everything, she has a very good way to explain things which also makes me interested in learning more. Thanks Rhonda. :)) 40 Katherine Sawick Katherine Sawick 3 years ago This young woman is amazing! She teaches a very complex subject at a level that a novice can understand and benefit from the entire lecture. There is absolutely none of the self centered blah, blah, blah that most YouTubers bore us with. 31 Graceon DS Jones Graceon DS Jones 2 years ago What you do is so important, I wouldn't have an inkling as to why things have gone the way that they have if it wasn't for Rhonda and other health experts. Thank you. 3 enviro1001 enviro1001 3 years ago So complicated subject you, Dr Rhonda, make it so simple and easy to understand. Thank you. 12 The Fire Breathing Duck The Fire Breathing Duck 2 years ago Fascinating and informative lecture that is easily digestible and understandable. Thank you for sharing this information and thank you for the lecture/screen format - so much easier to follow the speaker and slides at the same time. 2 Jesse Ray Jesse Ray 9 months ago Dr. Rhonda Patrick is amazing! Love her and the work she does! Found her on Joe Rogan's podcast, which she is the guest on like 6 or 7 episodes (about 2 and half hrs each!). She is the reason I grow my own broccoli sprouts for my greens shake!! 3 jessica long jessica long 4 years ago So interested in actually putting this information into practice and hope soon that the medical community will be using nutrigenomics to help their patients achieve optimal health. There is not a one size fits all approach to diet. 2 My Life the Parody My Life the Parody 6 years ago This interests me so much and it amazes me that doctors NEVER ask you what you're eating. 202 foreverkazi foreverkazi 1 year ago if my life wasn’t already devoted to another study I would solely focus on this, amazingly interesting information 2 coachraylo coachraylo 2 years ago Very good teacher. I am learning a lot from her. 2 Green Deane Green Deane 6 years ago You Go Girl! Providing a service with 23 and Me data is an excellent move. I'll do it as soon as it is available. 2 mrdarryl2row mrdarryl2row 5 years ago Great talk. I haven't heard Dr. Rhonda talk about vitamin k2, an important co-factor, that should be taken along with vitamin d supplements. Can she address this too? 13 Jared Verax Jared Verax 2 years ago She forgot to mention that folic acid isn't folate. It's the synthetic version and people with the MTHFR mutation, which is a LOT of people, have a hard time utilizing folic acid and it might actually work AGAINST what folate would do. 22 The Showing Agent The Showing Agent 2 years ago Keep up the good work Dr. 2 armadillotoe armadillotoe 2 years ago Thank you. This helps to explain the genetic link in obesity. 1 ALEXANDROS VASSARAS ALEXANDROS VASSARAS 2 years ago Thank You Rhonda Patrick, for your marvelous work !! 2 John Robertson John Robertson 2 years ago Amazing talk! Love the picture of all the metabolic pathways. 🙃 🙋‍♂️✌🇨🇦 4 Emre On Emre On 2 years ago Most physicians are not able to make the time to keep up with these findings, however a paradigm shift is very soon in order, this is HUGE! It's going to lead to a major goldmine in the philosophy of mindsets, nutrition, fitness, drugs, and other environmental variables to enhance the health of our lives, and perhaps even alter the aging process. Now we can better understand why some genes have variance in phenotype rather than simply assuming its the environment (abstract statistical reasoning). 2 Edward Russell Edward Russell 3 years ago This is useful for our physical self... we need to also think about our real self based on our thinking and reasoning. Creating a self and then developing it within the permanent values. Why? Because this self is what we need to create which takes us to the next life... body is merely a carrier... 5 Aras B Aras B 2 years ago Around minute 20:00 to 22, Dr Patrick speaks about vitamin D levels of pregnant women affecting seratonin levels in the developing brain of a baby, and how it affects autism. I wonder if this relates to older women having a higher risk of autistic children, as with age, our ability to absorb vitamin D is reduced. It may also have something to do with children born at different months of the year having different personalities, as their mother experienced different amounts of sunlight exposure during different times of brain development. 17 Mark Harris Mark Harris 4 months ago This lady's scholarship is phenomenal. 1 istvan antal istvan antal 1 year ago I think it is also important to let people know that it is very important to take vitamin D with a fatty food for maximum absorption. 1 Fuzzy Bunny Fuzzy Bunny 1 year ago Fascinating! Makes me want to eat healthier but I’ll forego the spinach since it is too high in gut damaging oxalates. 1 Master Chief Master Chief 2 years ago (edited) Basically eat, Good Fats, Lower your refined carbs, Eat your greens, Get some Sun, Go Exercise, Try Intermittent Fasting and be nice to your Mom 175 J. Curtis J. Curtis 2 years ago Fantastic work, bravo! 3 Monica Pretty Monica Pretty 4 months ago Thank you Rhonda!! awesome presentation!! Jami Carpenter Jami Carpenter 1 year ago Rhonda you’re amazing 💞 3 Rondie Rice Rondie Rice 3 years ago Very informative! 5 Ken Elliott Ken Elliott 1 year ago She's just so good! Impressive! I would so like to do some work with her if she needs help! IW Nunn IW Nunn 3 years ago Over my entire life, no Dr has ever wanted or offered to test my D3 level. Just recently I had to ask to have mine tested. 27 zxyx1 zxyx1 6 years ago amazing presentation as always! ;) 2 etofok etofok 3 years ago THANK YOU. You are saving lives 23 Larry Hutcherson Sr Larry Hutcherson Sr 1 year ago (edited) Awesome information delivered by an awesome speaker. Thank you. BTW: I'd really like to interact with her genes. 1 Tonya Koceja Tonya Koceja 2 years ago HELPPP , I Had My Vitaman. D. Level tested 5yrs ago and it was 6 ~. That was at 40yrs old ~ Im 45 now and need it tested again like NOW ~ I have also had a lot of these problems you discussed in this lecture ! 3 Ken Gilliland Ken Gilliland 3 years ago Thanks for sharing this very important video, Dr Rhonda Patrick ROCKS ! Keep On Truckin' 7 Claret trejo Claret trejo 3 years ago (edited) Great information. Thank you ! Smart and very beautiful doctor 4 dou40006 dou40006 2 years ago I am not so sure about the recommendation of vitamin be above 35ng/L. From I read recently our real need are more like 25ng/ L . We have been brainwashed 10 years ago about the promises of vitamin D supplementation, but it didn’t materialize by a reduction of cancer or diabetes or heart disease. But very interesting talk overall and great talker 1 Richard Tyler Richard Tyler 3 years ago Still the coolest person on the internet 35 poosta7 poosta7 4 years ago Dr. Patriek's presentations are fantastic! Liliana Torres Liliana Torres 2 weeks ago Me encantaría entender bendiciones para usted es muy inteligente todo lo que usted hace y sabe Alex Berukoff Alex Berukoff 2 years ago LOVE THIS GIRL 5 Jose Miguel Mandolesi Jose Miguel Mandolesi 4 years ago She is great! 3 Faz A Faz A 6 years ago Metabolism is complex indeed - individual. Despite the accessibility of these research findings, the sick-care medical system's only tool is pattern recognition - excepting functional/environmental doctors, most physicians unaware of polymorphisms etc 6 David Crandall David Crandall 2 years ago But in some cases, eating kale might not be as healthy as you think. For example, it can interact with thyroid function if it's eaten in very high amounts. It contains something called progoitrin, which can interfere with thyroid hormone synthesis and essentially block the iodine your thyroid needs to function. Eating too much of it may be giving yourself low-level poisoning of the toxic heavy metal thallium. IW Nunn IW Nunn 3 years ago The government and medical community will never focus on preventative care that involves nutrition. It's too effective and profit prohibitive. 59 Deborah Simon Deborah Simon 3 years ago I love Rhonda's videos. But I think she jumped the track a little in her answer to the last question.The questioner was asking for practical advice about whether or not most people should take multivitamins. She made some great points, such as too much folate being bad (because it can feed cancer), but my understanding is that she feels that --- in sum ---- yes, people should take a good multivitamin, unless they have a specific reason, such as a cancer diagnosis, not to. I think this was the information the questioner needed to hear. 2 Rich Pickard Rich Pickard 3 years ago Rhonda is so smart! 31 David Beaton David Beaton 2 years ago Great talk. So much to absorb. Just remember the average punter does not get it. I’m a biochemist and it’s still a lot to assimilate. Scott Dinger Scott Dinger 3 years ago Love her. 4 nomparfait nomparfait 2 years ago What about astragalus root for protecting/improving telomere length (combined with diet /D3/Mg of course) & impact on long healthy life? 1 B Sweet B Sweet 3 years ago I've never been so informed on a level that Wouldn't ever come up in a conversation wow however I have rewind a lot lol thx 7 Bracha Almond Namu Bracha Almond Namu 1 year ago Can a course be designed for high schoolers to have a window into wholistic nutrition? So much ignorance, and so much being discovered constantly. Would be great for young people to learn more about their own bodies. 1 kcromwell82 kcromwell82 2 years ago Today we know that we know very little about the gut microbiome. So many carnivores doing so well with zero veggies. 8 Ryan Ryan 3 years ago Wtf where has all this information been from all the other doctors? Found Dr. Patrick from Joe Rogan. 63 skyisthelimit ʕ •ᴥ•ʔ readyornotfor2 skyisthelimit ʕ •ᴥ•ʔ readyornotfor2 5 years ago Don't forget that Omega 3, DHA and EPA are also found in seaweed...(kelp also has vitamin D) where the fish got it from in the first place. 10 Big Ben Big Ben 5 years ago She is a sunshine 113 Grounded in First Principles Grounded in First Principles 1 month ago Has the Prometheus alternative on Found my fitness been released yet? This is gold. alex matheson alex matheson 1 month ago So well spoken Frank From Upstate NY Frank From Upstate NY 3 years ago Gotta wonder in how many years....(if the planet still exists), will one be able to confront one's polymorphisms...and have genetic manipulation in vivo. Obviously, we'll be doing massive in vitro work...but, how about the whole organism? Does this make sense? Home Life Together Home Life Together 1 year ago Wow! That was fascinating! 1 Taylor Dillon Taylor Dillon 2 years ago Dr Rhonda Patrick you are saving my life! 1 my name my name 2 years ago Thanks Rhonda, big fan , found you through JRE. RealJayJobes ジェイジョブズ RealJayJobes ジェイジョブズ 4 years ago I really appreciate how carefully you speak. 1 ZacharyTech7 ZacharyTech7 2 years ago (edited) I have genetic MTHFR VDR Taq BSM both +/- i have low vitamin D b4 supplaments was 14 now at 24 with supplements. i have congenital heart disease too. recently diagnosed with 22q11 which is low calcium. oh also have high functioning autism. but lots of sensory issues, Alexandre Magalhães Alexandre Magalhães 1 month ago I want to rewatch this again and again Bryan Naylor Bryan Naylor 2 years ago Could you do a presentation on bioavailability ? Tim Tim 6 months ago Thank so very much Dr. Patrick. You hard and brilliant work is GREATLY APPRECIATED and needed to millions. Tim from Kansas Thank You Carrol Lindsay Carrol Lindsay 1 year ago Metabolic pathways and phenotypes affect a second generation born that would influence the nutritional health or exposure to disease. My second question maybe there is not a direct response but can you give a general idea why most doctors do not ask questions if regarding nutritional intake, Nirmala Drieskens Nirmala Drieskens 1 year ago Great video♥️♥️♥️ Rob I Rob I 1 year ago 23andMe is something I would NEVER use, as they are sharing/selling your information to the medical industry, and there is little regulation on how this could be used against us in the future. Though perhaps sounding conspiracy theory-like, we’ve already seen a similar thing with our personal information and many, many companies like Facebook, Experian, etc, etc. 2 144Donn 144Donn 2 years ago Dr Rhonda eats this stuff for breakfast! Just amazing! 1 Bart Den Bart Den 1 year ago (edited) That is a good speaker ! - Tons of info, very fastly said. And structured. ... A BOMB. And she looks awesome and young. I'm gob-smacked. 1 Liselotte Johansson Liselotte Johansson 1 year ago You are just so Good! Thank you Ronda very interesting! B R I B R I 3 months ago Great information... Rob I Rob I 1 year ago One of the issues with supplementation is that there is always a small percentage that get adversely affected so you have to be aware of caveats. For example, the first question from the audience was a man asking about eating spinach: too much spinach eating by older males can be a problem with regard to excessive iron levels. Same for Vitamin D where some people with kidney or liver issues which affect the conversion of Vitamin D, where some people may make TOO much D and suffer some toxicity effects. For the most part, it seems mont people are D deficient. Dr Holick should get some credit for his long-time work to push for higher D levels and more awareness on D deficiency. 2 astromob1 astromob1 2 years ago Does one get the vitamin d polymorphism from one of both parents? In other words if one parents had polymorphism does it get passed on to offspring? Mo Turn Mo Turn 1 year ago Absolutely stunning work 2 Claire Wheeler Claire Wheeler 2 years ago For the veggies and vegans algal oil is a good choice for omegas including Dha. You can bypass the fish and go straight to source. https://draxe.com/nutrition/algal-oil/ Other oils that are good for omegas are hemp seed oil flaxseed oil. Spirulina in dry form is full of good nutrients. We dont have to rely on animals to gain our nutrition. Now I will watch the end as this is ultra interesting. Maurice Upton Maurice Upton 2 years ago (edited) Once we reach 65 & retire, the economic system hopes that we expire. The level of chemicals that we are exposed to in our daily working lives shortens our lifespans IMO. Also a Swedish study has pointed out that since 1945 the levels of different types of cancers has increased (excluding lung and skin cancers). This suggests to me that since open air nuclear testing began the levels of cancers seen in humans has significantly increased. Prior to 1945 many cancers seen today we're not seen or even as common. A persons body only has to come into contact with 1 Radioactive hot particle floating around in the atmosphere to cause lasting damage and cancer. 1 1aliveandwell 1aliveandwell 1 year ago Who decides what medical schools teach? Tried to get a Dr to measure active vite D as well (none of the Dr's saw would !! ). TY for a good vid ! 1 Digger D Digger D 2 years ago Wish this was 5 minutes long - then I would watch it. Damian Damiano Damian Damiano 2 months ago thank your for the lecture Rhonda , compare to your "anti aging " Godlike harvard MIT friends you deliver some information what can be put into use . But 55 min talking about staying in sun while we all know how important its MotoknivesandgunsbyJT MotoknivesandgunsbyJT 2 years ago MD’s are like lazy cops; they are not proactive. They are reactive. They deal with your problems once you get them. A good cop (and DR) will be proactive and educate you on how to NOT BE a patient. 3 yugoelvis yugoelvis 3 years ago The only Dr. that I really like! 2 carpe diem carpe diem 2 years ago Dr. McDougall of the Starch Solution says potatoes hold all the micronutrients we need, and Dr. Patrick, et. al., say eat your greens. Somebody is not correct. BTW, I believe Dr. Patrick went vegan. Murtaza Chishti Murtaza Chishti 4 weeks ago Brilliant 🤩 Jay Edenfield Jay Edenfield 2 years ago She's beautiful. Her mind is beautiful. 1 Bobby Ocampo Bobby Ocampo 1 month ago What is the basis of Magnesium Daily allowance requirement? How about those who only eat meat and are healthy? Michael Piatt Michael Piatt 3 years ago She is amazing but this is so over my head. 😂 1 John Kirton John Kirton 2 years ago Very good presentation. How come the audiences for these types of health promoting events often look so old and with BMI>25? 2 Live, Learn and Teach Live, Learn and Teach 1 year ago I'd love Rhonda Patrick to talk to Dr Stasha Gominak about vitamin D. Rak Hit Rak Hit 3 years ago (edited) That second slide thoooo... You know what, think I'm just going to fast forward to where you just tell me what I should be eating and how I should be eating it 👀 1 Alba del Valle Alba del Valle 2 years ago Meat from pastured ruminants is a much more bioavailable source of all nutrients, including magnesium. 1 Pawan Sharma Pawan Sharma 1 year ago What is the difference between to eat or make a vitamin D3 in human body 1 Mark Mitchell Mark Mitchell 5 years ago Very interesting work, some of which explains what we already observe in life. However a couple of comments are worth making. Dr Patrick offers a "throwaway" comment about bread, including it her list of "junk foods'. This is inaccurate inasmuch as "bread" covers a wide range of foods, some of which are highly processed (white flour and sugar) while others are extremely elemental (whole rough grains with water yeast and little else) which are very health promoting (rich in fibre, vitamin E, protein, antioxidants, etc.). Research published this week (from Harvard) for example links higher rates of Type 2 diabetes with avoiding gluten and whole grains. A second observation is that Dr. Patrick appears to be a keen proponent of smoothies, which are a convenient way to consume fruits and vegetables but reduce demands placed in digestive system and raises the glycemic impact of foods (it is processing, after all) and so may be a double edged sword (so to peak). 3 David Villarreal David Villarreal 3 years ago This Chica Rocks. 1 John Redmon John Redmon 6 years ago But isn't it an important question whether Vitamin D needs to be activated from the sun - and that the Vitamin D capsule is perhaps not activated? 3 Mark Ziegler Mark Ziegler 2 years ago More and more foods you eat have proteins that are melded with .glyphosate herbicide which calls for another look. Gary Ordo Gary Ordo 2 years ago dear dr. Rhonda Patrick, please make lots of babies and train them well in nutrition! 1 PoliClips PoliClips 2 years ago So if I want to enjoy my red meat, all I have to do is bake it instead of frying it to be on the safe side? 1 Michael McGee Michael McGee 4 months ago (edited) She's got off the charts smarts this one. Goldena Medina Goldena Medina 2 years ago Fish is wonderful but what about grassfed beef? 1 talkingstick2u Joy talkingstick2u Joy 3 years ago She lost me when she started talking about meat. Wish she addressed the China Study. I have 5 siblings with Hereditary Spastic Paraplegia and am very interested in epigenetics.... they are all meat eaters. My theory is that the whole foods, plant based diet is the reason I don't have this awful hereditary disease and am hoping that my kids don't get it either. 1 badmoon rising badmoon rising 6 years ago Will I be able to use your genetic tool from my raw data downloaded from Ancestry? 1 Martin Irving Martin Irving 3 years ago Interesting how she shows her subconscious bias in giving pork as an example of a high saturated fat source. 張永蔚 張永蔚 4 years ago is it a reversible process for the obese people having sperms with less ME? Lara Cwass Lara Cwass 3 years ago Is she suggesting that saturated fat is only destructive to those with this specific gene polymorphism? Polyunsaturated fat is highly toxic and inflammatory at the levels most Americans consume it. AR H AR H 2 years ago How does a person with hypothyroidism get their nutrients like magnesium if they're told to stay away from cruciferous vegetables? E46325mod E46325mod 3 years ago If she was a teacher of mine in college I would have been a doctor instead 1 Patrick Ryan Patrick Ryan 3 years ago 25:22 How can you recommend omega 3's or any polyunsaturated fats. "Poly" means many and "unsaturated" means fragile double bonds which break easily and cause free radicals to form to damage your cells.. Karolina Neumann Karolina Neumann 3 years ago (edited) I dont get it: center of Europe: no olive oil, no avocados, nearly no fish, only farming and cheese: and grand grandparents were always healthy with cheese, milk, meat...?? They didnt had any exotic imported food. 5 Richard Breeze Richard Breeze 1 year ago This is a deep dive if ever i heard one. David Crandall David Crandall 2 years ago I can tell Rhonda has a beautiful body. Even though she's been sitting around studying a lot. Bruce Hutchinson Bruce Hutchinson 1 year ago (edited) The nutrition bar Dr. Bruce Ames has been developing is available commercially as of the beginning of 2020. Healthright Nutrition. It is expensive $7.70/ bar $100 a package. Currently on sale for 50% off. Excellent product. Tom Boardman Tom Boardman 5 years ago grass fed Jersey cows produce the best for you milk, living milk is raw whole milk! the myth about milk is bad is unproven!!! Fat is our friend!!!! :) 4 devotae devotae 3 years ago Do you have permission to post this? I ask because in the description there are no links to her page or any refs of what she is talking about or where to find what she refers to. 2 Mark Read Pickens Mark Read Pickens 3 years ago As of this moment, forty people gave this "thumbs down." My first guess is "religious nut jobs." 1 Pedro Pedro 2 weeks ago She misspelled vitamin D3, for vitamin D and vitamin D2 G. S. G. S. 4 years ago what about the saturated fat from coconut oil ? are we going to jump onto the "bad" oil wagon again ? 3 jerry jerry 2 years ago Someone please tell me how to repair degenerated discs or painful spinal discs Captain Diabetes Captain Diabetes 3 years ago only 1000 iu increase by 5ng/ml ? Én egymagam Én egymagam 1 year ago Sugar is the worst thing you can eat. And - surprise! - there is glucose-fructose syrup in almost every food. From GMO corn. Bon appétit! Robs Pierre Robs Pierre 1 year ago Don't forget to think good thoughts. David Crandall David Crandall 2 years ago She wrong. The fats in bacon are about 50% monounsaturated and a large part of those is oleic acid. This is the same fatty acid that olive oil is praised for and generally considered "heart-healthy". Wilkens Brito Wilkens Brito 6 months ago 32:39 Bless you SH SH 1 year ago Thanks Timmy Bobinson Timmy Bobinson 3 years ago Asians eat a lot of stir fried food. Is that different to Western frying methods? How do they cope with the carcinogens using high heat frying method. 3 Cameron Jinks Cameron Jinks 3 years ago Rhonda Patrick, you are sooo beautiful and smart 1 johnny 1600 johnny 1600 1 month ago This chick is a badass ras mus ras mus 3 years ago OMG that body she packs!!!!!!!!! Don Sal. T. Don Sal. T. 2 years ago Chlorophyll!? more like... na jk I'm 32 going on 33 gonna pay attention this time. Be well. Darel G. Darel G. 5 years ago This is going to piss off my Doctor. 6 martysk8r martysk8r 1 month ago 40:12 Healthy food sample - Yummmmmm Brian MG Brian MG 3 years ago On one end her missing the weight was shameful, on the other.. the extra jiggle was appreciated. Brandon Asif Brandon Asif 2 years ago Rhonda "polymorphisms" Patrick 1 C Barron C Barron 2 years ago She is dope Sand paper Sand paper 5 years ago Im watching the video but my minds somewhere else ffs WHY CANT I JUST FOCUS!!! 3 Shehzad Khan Shehzad Khan 2 years ago Pretty and intelligent. This gal is HOT! Dale Kriens Dale Kriens 4 years ago you are so unbearable hot. lol I have a extremely overweight wife that I just can't get through her head how important this stuff is.... 3 Jose Miguel Mandolesi Jose Miguel Mandolesi 3 years ago She is vitamin d. 1 Phoenix Risin’ Phoenix Risin’ 2 years ago Intelligence is hot! Tehonrerzx Tehonrerzx 6 years ago Lol, at 41:33 it makes it sound like she didn't do anything Stephen Tack Stephen Tack 5 years ago @33:35 "Over 9000!" dariusz warwas dariusz warwas 2 years ago it all start with the stomach and ends with the stomach . all you have to do is to talk how to make your stomach healthy , that all . Potito Gradone Potito Gradone 4 years ago (edited) Brilliant Rhonda. But what's with the fish? lovely fish lovely fish 3 years ago Too bad there is no young people go to this kind of lectures....always old one the eat bad in there life and they want to live longer . 2 Christopher Walken Christopher Walken 2 years ago cool SuzieQ Wonder SuzieQ Wonder 2 years ago EAT YOUR GREENS! Ivan Eccles Ivan Eccles 2 years ago And a beautiful lady 😋 1 B M B M 3 years ago Is it safe for an 18 year old to take 5,000 iu of vitamin d3 a day. I do not know if I am vitamin d deficient but I do not get a lot of sunlight. is this safe ? Master Chief Master Chief 2 years ago NAT Network 9:21 Zen Lyf Zen Lyf 2 years ago WILL U B GIVING THAT TO FBI AS WELL wag1 wag1 3 years ago 17:50 red baron red baron 5 years ago bloody adds Maja Vidmar Maja Vidmar 1 year ago 1aa Rich Johnson Rich Johnson 2 years ago I have a headache! Tim Tim 6 months ago No excuse for not proof reading public comments. Referring to my very recent comment. TheRedPIll TheRedPIll 3 years ago I hate what we do to mice and other animals for testing. Yes it’s interesting and helpful, but wrong. 2 Nos Controlan Nos Controlan 4 years ago Great source of information, but I don't like the accent very much. "impoornt" PAINS 2022 PAINS 2022 2 years ago INTERESTINMG BUT TOO LONG..could be shorter and simpler..we dont need somuch detail Tommy Edge Tommy Edge 2 years ago Wrong Non Available Non Available 2 years ago Actually you're far better off not eating any animal products at all !! #Triagetheory #supplements #diet Bruce Ames on Triage Theory, Longevity Vitamins & Micronutrients 137,072 viewsFeb 11, 2015 3.2K DISLIKE SHARE DOWNLOAD CLIP SAVE FoundMyFitness 424K subscribers In this video Dr. Rhonda Patrick interviews Dr. Bruce Ames about his triage theory, which he proposes that the body has developed a rationing response to shortages of micronutrients (vitamins and minerals) throughout evolution. When cells run out of a vitamin or mineral, that scarce micronutrient is allotted to proteins (in the body) essential for short-term survival. Proteins needed for long-term health, including those that protect DNA, lose out and become disabled and lead to diseases of aging. In addition they discuss how RDAs are chosen and what Bruce calls “longevity vitamins” which he calls a class of nutrients that exist mostly to prevent degenerative diseases of aging in addition to essential vitamins and minerals. Sign-up for the weekly email newsletter: http://www.foundmyfitness.com/?sendme... Crowdfund more videos: http://www.patreon.com/foundmyfitness Subscribe on YouTube: http://www.youtube.com/subscription_c... Subscribe to the podcast: http://itunes.apple.com/us/podcast/fo... Twitter: http://twitter.com/foundmyfitness Facebook: http://www.facebook.com/foundmyfitness Instagram: http://www.instagram.com/foundmyfitness Chapters 00:00:00 - Introduction 00:02:36 - Triage theory 00:15:21 - Vitamin K 00:21:07 - RDA vs RDI vs EAR 00:31:45 - Vitamin D 00:36:28 - "Enough is enough" 00:41:42 - Diet vs supplements #Triagetheory #supplements #diet #longevity Chapters Introduction 0:00 Triage theory 2:36 Vitamin K 15:21 RDA vs RDI vs EAR 21:07 Vitamin D 31:45 Enough is enough 36:28 330 Comments rongmaw lin Add a comment... Carol Tosi Carol Tosi 3 years ago I loved this video. You can see the respect that Dr. Patrick has for Dr. Ames and he for her. What a blessing for Dr. Patrick to have worked beside him and undoubtedly learned from his years of experience and wisdom. And what a blessing for him to have someone so brilliant to working beside him to certainly continue his research! And we are all blessed for having them in our world! 60 Roland Amaranto Roland Amaranto 7 years ago He's 86 and dedicating his time to research and share these vital information for the benefit of all. Thank you Dr.Ames, and to you to Dr.Patrick. :) 170 Pablo Cohen Pablo Cohen 4 years ago What an eloquent man. Natural teacher. And a fountain of knowledge, thought and connectivity in investigative nature. Thank you so much for your time and efforts. 40 Cara Cee Cara Cee 7 years ago You two have just further developed my interest in pursuing a career in nutrition. With my biochemistry background I can totally understand how these scarce nutrients could become such a huge problem. Nutrition is soo fascinating and yet such a huge necessity. One can't help but to research how much of what and when and where it's needed! 43 KevNoonz KevNoonz 5 years ago Dr. Ames literally is out of this world; ethereal; brilliant. 41 poleag poleag 2 years ago Triage theory transformed my thinking and got me interested in vitamins and minerals again. Thank you, Bruce Ames. 13 David Eade David Eade 4 years ago I LOVED the interview! It was fun to listen as it reminded me of how lucky I was to have Dr. Ames explain his assay in my nutrition class and then to perform assays using common toxins found in sprouts, mycotoxins in corn. The conversations we had with him were tremendous and gave us insight into how food safety and research is done. I thoroughly enjoyed this 30 year reunion! :) 4 Carter The Chi Staffy Carter The Chi Staffy 1 year ago This dude is 92 now and looks healthier than he did in this video! 22 Søren Skjold Jensen Søren Skjold Jensen 2 years ago I learned so so much from you two talking, Dr. Rhonda! This is really a great message to everyone on how we should look at nutrition – our deep relationship with foods i.e. plants. Thank you so much :) 3 Danielle Shine Danielle Shine 3 years ago This man is SUCH a legend, GO BRUCE!! Thank you for all you do. 6 Grainne F Grainne F 7 years ago Dr. Rhona and Dr. Ames, can I just take this opportunity to thank you for your work and especially for trying to distil the science for the lay person like me. You are on the cusp of a revolution in people taking their health into their own hands, and you taking this precious time to make videos, do podcasts with others etc is a vital part in getting this information out there. I'll pass on the word as best I can. Hello from Ireland and thank you again. The world is such a better place for people like you. Regards, Grainne 2 Joon S Joon S 7 years ago This is my first exposure to the great man that is Dr. Bruce Ames. What a wonderful human being, it must be such a pleasure to have him as a mentor. Thanks Rhonda for all the amazing knowledge you have to share with us. I walked away from this video feeling enlightened. 2 Kev n Ash Griffitts Kev n Ash Griffitts 7 years ago Amazing interview! People just clear your heads of what ever you think you know and do what Rhonda does. Awesome!! 9 priceandprice priceandprice 1 year ago Dr Ames, love this talk and your dedication to science and health. Dr. Patrick you are a super star and I look forward to every video. I have so much respect and admiration for you and your work 2 Texas Casey Texas Casey 2 years ago I have watched this video multiple times - Dr Ames is a gift. Thank you Rhonda! 10 cynthia Lee cynthia Lee 2 years ago This is really awesome. Very well done. Thank you both for the work you do and for sharing it. 2 Classical Pilates Centre Classical Pilates Centre 4 years ago Dr Patrick, I love your videos! You have the rare ability to share complex information in a way that makes it intelligible to the layperson without drumming things down. The same is true of Dr Ames. Thank you for your work! 3 DeskTornado DeskTornado 5 years ago The information on folate deficiency is so valuable. I have the MTHR mutation and take extra folate. But I understand that too much methylation can also cause problems, like cancer. Dr Rhonda, I wish you could talk about this issue because I never see the explanation or studies anywhere of how much folate is enough but not too much. 2 eagleswingsec eagleswingsec 1 year ago Back in the 90s, my prof described a “hierarchy of need” related to health and nutrition. The most important organs get first dibs on vital nutrients. His wording was different, but he was describing this triage theory, really. 3 DeskTornado DeskTornado 5 years ago What a treat it is to see an interview with the infamous Bruce Ames! Thank you! If our educational system were better this video would have millions of hits! 14 trishtrinitron trishtrinitron 4 years ago Thank you so much Dr. Ames and Dr. Patrick for uploading this very insightful discussion on You Tube. Rhonda's questions were always right on target in eliciting the most valuable biochemical principles from Dr. Ames' profound understanding & experience in this field. As a biological scientist I've been frustrated by the disconnect in nutrition & biochemical outcomes versus overall human health that is presented by people with little research knowledge of the field. Thanks again because you both have vastly enriched my approach to nutrition. 1 Bill Zajac Jr Bill Zajac Jr 2 years ago Bruce and Rhonda, thank you both for all you do and I hope you keep doing it for a long time. 1 El Rey El Rey 6 years ago Fantastic interview with two lucid experts - I took a lot out of it. Also laughed out loud at Dr. Patrick's reaction to the Mae West quote. 5 mitch cumstein mitch cumstein 5 years ago An excellent video. Great conversation! I've actually taken a lot of your vitamin and nutrition advice Dr. Patrick. Thanks so much! 1 sillykidsnow sillykidsnow 4 years ago Awesome interview!! Explained so much so clearly!!! Thank you!!💖😀 3 MRS. DL Lieberman 360 MRS. DL Lieberman 360 1 year ago Dr. Bruce Ames, you have earned our respect both by your age and your significant contribution to all. You are indeed a man of high distinction and deserving of such. 1 Robert Sutherland Robert Sutherland 4 years ago I just love Dr. Ames. I've followed his information for a long time. 4 Jungle Theme Jungle Theme 3 years ago Thank you!! I dont know if you read these... but I would love to know the tests I should ask the doctor for in order to tailor my diet. I am loving all of your work on youtube and have to pause the video every 10 minutes or so to research a new word I have never heard of haha. Love it. I love the little definition pop ups too. Would love more like a picture for the natto mentioned and perhaps a more direct advice on exactly which suppliments you reccomend. So far (with your vids) I am up to PQQ, D3, B complex, hydrosuminsumin collagen, salmon roe!. But in your podcast w joe rogan you mentioned that getting your biomarkers..marked.. can let you know if crusiferous vegetables or a keto diet etc. (Not into it) would work for you or not. Would love more videos on clarifying what steps a layperson can take to fine tune thier diet and excersize from really basic finances and educational background, because as you said for each opinion there is an opposite and it is so difficult to figure out the most recent/correct info. Fangirling hard excuse me. 3 peeness mcgoo peeness mcgoo 7 years ago Fantastic! What a brilliant man. Truly amazing work sir. Triage theory is spot on! 18 Alfonso Hunt Alfonso Hunt 5 years ago An additional thing to what Bruce talks about at 39:17 would be the ability to quickly analyze the nutrients in the food that is about to be eaten. Being able to put a piece of food in a device and have it quickly spit out all the nutrients and then combine that with the blood drop test indicating what is required. Once we get to that point then perhaps accidents will be only reason people don't live to their full potential. 3 tjames22123 tjames22123 5 months ago An absolutely fascinating interview. Thanks Dr. Bruce and thanks Dr. Rhonda!! 1 FoundMyFitness Mercury1955 Mercury1955 4 years ago Wow what a great interview. I feel like a sponge trying to soak all this up. Thanks much for your efforts Rhonda. Much respect to Dr Ames too. Getting old but mind is still sharp. Keep hanging in there! 1 Money moneyfishing Money moneyfishing 7 years ago 1000 thankyous for bringing the man who changed the way I look at nutrition. I asked you for this weeks ago and you delivered. Please tell Dr. Ames thank you. 9 Jeff Gilmore Jeff Gilmore 4 months ago What a great treasure this man is ! Thank You Dr Patrick! I am thrilled to have found you both!! Carllie Way Carllie Way 6 months ago Thank you both for this amazing interview. It inspired me a lot :) 1 alfred Vincent alfred Vincent 1 year ago Thank you Rhonda and Dr. Ames. Your focus on prevention is so important yet so ignored in this country. 2 Roger1uk Roger1uk 6 years ago Hi Rhonda,great video with Bruce, listening to you and him was amazing,he backed up my thoughts of a daily multi-vitamin being good insurance! What are your thoughts on things like lipoic acid and grape seed extract which I have been taking daily for nearly 10 years? 3 IAmAgainst IAmAgainst 4 years ago I hope he lives long enough to receive a Nobel prize.. 111 P X P X 2 years ago Amazing Dr. Bruce as 86, great scientist still transforms the medicine! 1 Harold Baker Harold Baker 3 years ago (edited) Thank you both for this fascinating conversation. I got a kick from the joke about exercise, a sense of humor may not be an essential nutrient, but it is important. I wonder if there has been any research on the effect of pharmaceutical drugs on micro-nutrient levels? Pharmaceuticals are so widely taken, especially by older people, who may be taking several different medications, for blood pressure and diabetes for example. 1 Leslie Hayman Leslie Hayman 6 years ago I absolutely appreciate what you're doing and the clarity with which you present! I am repeatedly asked why scientists talk about our need for "Folic Acid", particularly if it is a human-synthesized chemical upon which populations have not relied for health, prior to its deliberate introduction. In this video, you discuss with Dr. Ames, the deficiency of "Folic Acid" having a role in single carbon transfer (maintenance of cellular electron chain...metabolism). Can you please clarify and let us know the natural form of the substance that is required to avoid deficiency and the breakage in chromosomes or loss of DNA? Folate? MTHF?...and everything that goes into it? Perhaps Folic Acid is a summary characterization of a collection of substances: Micro-nutrients are not single-shot cure-all and play dynamic roles in complex (interconnected) dynamics. Yet,, Dr. Ames epiphany about Folic Acid deficiency and Radiation isn't likely a statement about life's dependency on a commercial product. Coach Emma Rubio, MSc Coach Emma Rubio, MSc 5 years ago Thank you to both of you, for your work and information. 1 Colin Maharaj Colin Maharaj 6 years ago I have not listened to this video yet. Just the first 2 mins. But I am so excited that this guy is alive and well enough to keep going in his field. I wish to meet one of these greats one of these days. 2 Gary Ordo Gary Ordo 2 years ago Thank you dr. Rhonda Patrick and dr. Bruce Ames you guys are the best! Geniuses at work showing love! 3 heymisterderp heymisterderp 2 years ago "Bad nutrition is doing us in." So true, yet a big reason why this problematic issue is so difficult to unravel is because such research goes against what must be 99% of the profit streams of conventional healthcare. 2 francis bertolini francis bertolini 1 year ago Excellent!! Love this man and you Rhonda! Thank you for your important work! 1 TheBusshelter TheBusshelter 7 years ago Awesome interview! Can always rely on your videos for great information 2 kipling1957 kipling1957 2 years ago This has so expanded my ideas outside of the regular box of “consensus biology” especially as regards to vitamins (or should I say the subset of compounds officially designated as such) that I will modify my undergraduate teaching of these concepts. 1 FoundMyFitness FoundMyFitness 7 years ago Here's a few great quotes from the video... 4:18 - “Folic acid deficiency does the same thing as radiation.” - Bruce 10:35 - “When you get a little low on any vitamin or mineral, it’s to nature’s benefit to ration it. Where would you expect it to ration it if you don’t have enough selenium, or Vitamin K, or magnesium? Well, it’s going to put it into those proteins that are essential for survival, because what nature wants you to do: survive and reproduce. Thats strong selection. Living to ninety? Nature doesn’t really care about about that, because you’re past your reproductive age.” - Bruce (on insidious micronutrient deficiency causing aging or “The Triage Theory”) 14:37 - “For example, in Vitamin K, the clotting proteins get it first… and only after they’re satisfied do you prevent calcification of the arteries, or prevent cancer, or prevent bone fractures. It’s all insidious damage that you get that’s a long term consequence. In fact, we call these the diseases of aging.” - Bruce (on The Triage Theory in selenium and vitamin k dependent proteins) 22:13 - “Over the years we’ve discovered these 15 vitamins, and 15 essential minerals… but it’s all based on some disease that shows up or people dying.” - Bruce (on longevity vitamins and the trouble with using only acute symptoms for defining essential nutrients) 23:20 - “I have an italian wife who feeds me a wonderful diet. She kept on nagging me that I should get more exercise. One day I said: when I feel like exercise I run my experiments, I skip controls, and I jumps to conclusions! I liked that joke so much I must have told her it fifty times and one day she said, "I’ve heard enough of that joke, I’m getting you a personal trainer!” So now I go and work out twice a week.“ - Bruce (on his exercise habits) 24:24 - “The EAR (estimated average requirement) is actually set two standard deviations lower than the RDA and people still aren’t even meeting that.” - Rhonda 25:25 - “What you want to know is… does it shorten your life? You can do those kinds of questions in mice, but those are expensive to do and no one’s been really doing them.” - Bruce (on studying deviations from optimal micronutrient intake) 31:05 - “The obese are eating the worst diet in the country if you define worse as ratio of calories to essential micronutrients. They’re just eating empty calories.” - Bruce 36:46 - “The docs are all used to randomized double-blind clinical trials, which makes a lot of sense because if you test a drug in people, no one has it to start with! But… applying it mindlessly to nutrition is stupid, because if 90% of the population has enough of Vitamin X and 10% are really deficient, you want to test it on that 10% otherwise you’ll never see anything because you’re diluting [your results] with the 90% that have enough.” - Bruce (on the problem of randomized double-blind clinical trials in nutrition) 38:12 - “Medicine has sort of abdicated [their responsibility]: most physicians know nothing about nutrition. They don’t get any training in medical school… maybe an hour or two lecture. […] I think prevention is going to involve different people. It’s going to involve people who know some nutrition and can figure out mechanism. The analytical methods are coming fast so that you’ll be able to put your finger in a machine and it will send the results to your iPhone.” - Bruce 42:05 - “If I don’t eat veggies with a meal, I feel deprived.” - Bruce 42:15 - “I think we all should try and eat a good diet. It’s actually a wonderful to eat a good diet, because you’re eating all of these different kinds of foods… and they all taste good, and when you get used to it, you feel better!” - Bruce (Originally shared at http://foundmyfitness.com/news/s/hopjwr/ ) 153 kipling1957 kipling1957 2 years ago One of the best “elevator” summaries of how nature trades long-term health for short-term health as an explanation for senescence. Thank you! Alirio Zavarce Alirio Zavarce 4 years ago Awesome interview. This is music to my ears. Very inspiring. 3 Furious Doe Furious Doe 2 years ago Fantastic Interview ....I hope Dr. Bruce Ames will live long and happy ... with good food . Both of you are hero's . 1 Paulry Barczyk Paulry Barczyk 7 days ago I'm really glad that I stumbled across this wonderful channel. With the health of people seeming to be in general decline now for decades, and with general health guidelines (like those discussed in this great video) almost never recommended, I'm starting to think poor health is a deliberate goal of the BIG-GOV-MED machine that controls such things. Strong healthy people are harder for the machine to control, and they're also less profitable. And yes, I know that sounds tin-foil-hat-ish, but it's the simplest theory that explains our reality. MrHazelglen MrHazelglen 3 years ago So much mutual respect shown in this interview. 2 Allen Miller Allen Miller 3 years ago Our Canadian Government stopped paying for the Vitamin D test. They said its not a vitamin (hormone) of importance. Never pays to follow the nutritional advise of your government. I usually do the opposite. (They recommend Canola Oil as a healthy oil. I'm sure its because Canada is the largest producer of Canola Oil.) 22 Adiudicium 1776 Adiudicium 1776 3 years ago Thank you Dr. Patrick for explaining the K1 relationship with the calcification of aa. Fascinating! Smitha Sharma Smitha Sharma 1 year ago This was so wonderful! Loved it! 1 Theosis Northam Theosis Northam 7 years ago Bruce N Ames PH.D Scientist, Jedi Master.. Love it... 57 francois tourigny francois tourigny 1 year ago Wonderful interview, thank you Rhonda. 2 threnody threnody 7 years ago Rhonda what do you think about green powders? I recently started taking some along with some kale powder I happened to pick up at my local chemist and I have to say I feel a bit more nutritionally "replete" after a serving of each a day and more naturally energized and relaxed. I usually eat almonds, blueberries and some vegetables but probably not enough to keep me feeling like I cover all my bases. How do you feel about these vs a traditional multivitamin pill/tablet? kipling1957 kipling1957 2 years ago What a privilege and an honour to work in Ames lab, Rhonda. I had no idea. 2 Randie Harrison Randie Harrison 1 year ago God Bless this man. May God grant him long life in Jesus name . Bless him for his work. Bless Dr. Ronda Patrick for her work also. 1 AnnMarie AnnMarie 1 year ago Clearly, the force is with him. And Dr. Rhonda. 4 Eric Eric 7 years ago Nutritional Sciences student checking in, defining certain terms in the lower third was a great touch for the non-biochemically acclimated. Great interview! :) 1 Vaughn Booker Vaughn Booker 1 year ago Been taking my vitamins going on 20 years now, never stopping. 2 ironman4850 ironman4850 6 years ago Isn't it vitamin K2 that removes the calcium (plaque) from the arteries as well as several other functions? A lot of good information. 12 Peter P. Peter P. 4 years ago Amazing ,thank you for sharing all this info! 2 The1RobynHode The1RobynHode 5 years ago I cured my vision issues in my late 20s when I took lutein/zeaxanthin and removed as many glutamate compounds (glutamic acid being okay). I realized alter that it was huge for me to get more morning sun (for UVA) and eliminated the electromagnetic fields away from my body and brain. The poor are eating a TON of glutamates, and if they are already excitotoxic with a lowered redox, it's just aggravating that lowered health even more. This all ties back to the mitochondria craving calcium, with calcium effluxing from some cells into other cells to compensate for the damage. More hydration folks... more sunlight for making a better charge separation in the water for more energy harvesting into the ECT with the mitochondria. Gerald Pollack is gonna get a Nobel prize someday. 2 blueberry11051 blueberry11051 5 years ago Great video. Hope to see more. And, thanks for posting it. 2 Steffen Toates Steffen Toates 7 years ago Great video. Keep up the great work. 3 David Rowe David Rowe 5 months ago This is a lovely video. Easy to follow. Rhonda “lives” Newtons words: I can see what I can see, because I’m standing on the shoulders of giants” 1 FoundMyFitness Alan E Alan E 2 years ago Fantastic interview. Your work and field is so intriguing. What an exciting life. 1 Wes Burton Wes Burton 7 years ago I love this guy! He's cool as all get out and the content of this video is terrific. Cant say enough. Thanks!! 2 D27Rugen D27Rugen 7 years ago this is sooo epic, its like they are talking on how to fix 90% of hospital related visits very cheaply instead of all these 'interventions' that cause thousands and thousands of dollars which is one of the reasons why we gota tank sooo much money on 'health' insurance, which funny enough does not ensure anything about been healthy, in contrast it might be stressing you out 'cause you cant pay for it. 11 nobody nobody 1 year ago Ein wunderbarer Mann. Tolles Interview. Danke dafür 1 sboho sboho 1 year ago Dr.patrick you are so great for bringing Dr. AMES here I always wished to see him the one who devised the Ames test so thank you More over your channel is so great I just stumbled upon it Thank you again marc amatucci marc amatucci 4 years ago This was wildly informative and interesting 1 Virtual Pilgrim Virtual Pilgrim 1 year ago Everyone loved this interview, So what are you going to do differently now that you've seen it? What is the practical thing you're going to do as a result of this discussion? jim dandy jim dandy 7 years ago Very interesting explanations of things I previously didn't know- I think the best way and healthiest choice would be SURE to eat a balanced diet of whole foods [organic if possible] and not concentrate on 1 thing while neglecting many others- Like your Mother used to say eat your greens and since I am now 59 I think nearly all food would be considered healthier or at least more organic than 'modified' foods of Today, I could easily stand corrected though Yes a few negative articles have been written on supplementation and its possible for people who truly eat a real, healthy balanced diet supplements might not be as necessary but basics like multi-vitamins, fish oil cannot hurt. While watching this I ate 2 mangos and drank a few glasses of spring water God bless Doctor Ames working 5 days a week at age 86 1 Karina Ramirez Karina Ramirez 2 years ago Awesome!!! I enjoyed this very much! He was a joy to listen to! 4 Fran Guarderas Fran Guarderas 7 years ago amazing discussion... thanks so much! 1 Liberty DIY Liberty DIY 7 years ago Wow awesome interview thank you both! 3 Fred Miller Fred Miller 7 years ago Great interview Rhonda? Thank you! I would love to hear a podcast on your take of whether or not long term use of soy products is harmful. I was a vegetarian for 25 years so I have a practical bias. To me, an indication that is soy and its phytoestrogen is not harmful is amount of it used in baby formula. An estimated 15% of infants use soy based infant formula. This presents a natural experiment. The evidence suggesting some issues in this population subset is questionable, but I am not a biochemist. 1 jhdgkjsh jhdgkjsh 7 years ago I didn't make the connection that this was the SAME GUY that invented the Ames test, until you mentioned it. That's crazy cool! 26 phil smith phil smith 4 years ago Are the "15 vitamins and 15 essential minerals" listed anywhere? A great video, thanks a lot. Rhonda always does a great job. joe bob marley joe bob marley 5 years ago Ya the Triage theory explains so much! Wonderful conversation. I am worried about Bruce taking fish oil pills. I just dont know if they are a good idea especially when the bezt form of omega fats are from plants.. RustyShackleford RustyShackleford 7 years ago Is this the guy who made the Ames test? Wait, never mind, you just said it. That's awesome you get to work with people like this! 3 4hero70 4hero70 5 years ago my 2 heroes....fantastic synergy 2 joe schmo joe schmo 6 years ago Btw, this is exactly the conclusion Ron Rosedale has come to (presumably independently) that the body (or any organism) doesn't care about longevity, it only cares about reproduction. Sure. The question becomes - what is the most powerful intervention we can exploit to promote longevity (if we care)? I'm with controlling insulin response and avoiding foods that promote blood glucose spikes. And, presumably, refined carbohydrates tend to displace important micronutrients. ("not a pretty picture because Americans are eating all these empty calories.") Southern Grandma Southern Grandma 3 years ago I wish they would tell us what we should eat to get the nutrients we need. That is what we really need to know to be healthy and not necessarily all of this scientific stuff. I don't believe we should have to take a bunch of pills to be healthy, if we eat the right diet. 3 joe schmo joe schmo 6 years ago Yep, what he mentions at 4:18 is a general problem. People are getting sick because of the nutrient deficient, modern industrial diet but the tendency is to blame it on environmental toxins (heavy metals, strontium, aluminum, lead, mercury, etc). Unfortunately, it's mostly the refined carbohydrates that are causing the diseases of civilization; particularly heart disease and cancer (because of their impact on metabolism at the systemic {endocrine} and cellular level). 11 bendtrucker bendtrucker 5 years ago One of the greats. Up there with Linus Pauling. 7 More Human More Human 6 years ago "What I postulated, just an idea that came to my head. When you get a little low on any vitamin or mineral, its in natures benefit to ration it. The way it rations it, where would you expect if you didn't have enough selenium, magnesium, or whatever. Whats nature going to do....it's going to put it into those proteins that are essential for survival. That is what nature wants you to do is survive and reproduce. Thats strong selection."- Bruce Ames That is a great piece...hope I quoted him correctly there, I was typing as fast as I could! 17 Paula Vaughn Designs Paula Vaughn Designs 4 months ago Brilliant interview!!! CYPRIAN KARIUKI CYPRIAN KARIUKI 1 year ago Dr bruce ames is a legend. DEB WEST DEB WEST 1 year ago Love him and this topic. ACURA4LIFE ACURA4LIFE 4 years ago Thank you Dr Rhoda your very smart beautiful and continue to share excellent information in my favorite topic Naturopathy: Orthomolecular Medicine: vitamins, sauna etc Sebastian Aguiar Brunemeier Sebastian Aguiar Brunemeier 3 years ago Bruce Ames is very intelligent. He must have been frighteningly sharp when he was young. 4 abracadabrascotty abracadabrascotty 7 years ago A wonderful scientist...my only point of contention would be that he should specify that there are over 90 essential raw materials that ur body needs in adequate supplies for optimum survival, as opposed to his highlighting the 30 or so...also, his comments on the body trading long term survival for short term survival is precisely what is happening with cancer...cancer cells are typically produced as a precise response mechanism of exactly the same nature of which Bruce speaks about to buy ur body survival time to both identify and eliminate the bacterial infection that has invaded ur body...this is why cancer cells always surround these underlying bacteria and are found alongside these bacteria, because the bacterial infection will kill u in a week if ur immune system is deficient (which it almost always is in cancer patients, via these vitamin and mineral deficiencies they have prior to the infection) so as a response mechanism ur body is fully aware that the body can survive for years with a cancerous mass...so ur body decides to purposefully create cancer cells in the area of this bacterial infection and ur body also makes these cancer cells a very desirable environment for these bacteria to be attracted to- anaerobic, acidic, etc...the last step is that these cancer cells purposefully eliminate their apoptotic pathway which results in them becoming "immortal" which gives the immune system the most amount of time to address and eliminate this bacterial infection before the bacterial infection eliminates the host...the biopsy process, the radiation process, the surgery process, etc. typically allow the underlying bacterial infection to spread all over the body which then this cancer response must "metastasize" throughout the body in an attempt to isolate and protect the body yet again from this underlying potentially deadly infection...the blind are leading the blind in this cancer arena i tell ya...the simple solution for cancer is to: 1. provide the vital essential vitamins and minerals, etc. to the body which will allow the proper immune function response, via these raw materials, to this infection 2. if not identified by the body, tag the infectious area with a bacterial or viral infection that ur immune system DOES respond to, because they will also be veryyyy attracted to the very same cancer cells...wait a week...cancer gone 3. provide the body with the necessary enzymes for clean up of the following dead debris 4. provide the body with the necessary GC-MAF to ensure that any small amount of remaining cancer cells are removed very much in line with the work of Bruce...this will work better than any current therapy for cancer...any questions feel free to ask...ok take care guys...good interview... ur friend, abracadabra 1 Charles Patrick Charles Patrick 1 year ago almost all of us have a genetic or other issue with bioavailability of one or more nutrients, B12 deficiency for example Transcobalamin or bowel structure/disease, there should be a common test to identify any and all nutrient deficiency issue or issues, administered at annual checkups throughout a person's life joe schmo joe schmo 6 years ago Boy, he went from ignoring nutrition because it was too complicated to becoming obsessed with minutiae. 3 Andy Wilson Andy Wilson 7 years ago Wow, Bruce is awesome. Great Video. ! 1