DNA methylation

1:42 / 38:34 122,418 viewsDec 12, 2013 1K DISLIKE SHARE DOWNLOAD THANKS CLIP SAVE Shomu's Biology 1.63M subscribers This video explains the process of DNA methylation and its importance in eukaryotic transcription using DNA methylase and Histone methylase enzymes. For more information, log on to- http://shomusbiology.weebly.com/ Download the study materials here- http://shomusbiology.weebly.com/bio-m... PPT source- Dr. Anindita Banerjee, Department of Microbiology, St. Xavier's college 75 Comments rongmaw lin Add a comment... wesG09 wesG09 7 years ago This was a very helpful lecture, thank you. For when I inevitably revisit this video, or for the sake of others, here are some time stamps: 0:00 Introduction 1:25 DNA Methylation 3:23 CpG Islands 5:42 Role of methylases/different types of DNA methylation 10:56 Methylation and transcription 14:54 Cross talk between methylation and acetylation 17:08 Gene insulators as gene silencers 20:36 Role of an insulator - genomic imprinting 26:19 Protein (histone) methylation 29:52 Coupling histone methylation and DNA methylation 34:10 Heterochromatin and euchromatin silencing 49 Alex Akbari Alex Akbari 1 year ago I am a self learner ,familiar with DNA RNA ,RECENTLY CAME ACROSS WITH. METHYLATION which looks very interesting Reviewed a lot of lectures ,understood them partially , now I am left with some questions about why methylation happens ,is that the only factor for cancers What is the difference between. The sequential mutation and methylation ending to mutation any reply is greatly appreciated .an old time student 1 Avni K Football Training Avni K Football Training 7 years ago Thank you so much for all your videos. Could you make a video on cell signalling, MAPK ie ERK Pathway, please? 2 L S L S 3 years ago I like all of your videos. Very informative and clear. Please could you do a video on CpG oligodeoxynucleotides. manoj mahajan manoj mahajan 7 years ago excellent talk..complex topic simplified in lucid manner..thanks a lot msmikymiks msmikymiks 6 years ago this lecture was very helpful...omg..i have a better understanding now...thanks a million!!! Sukrishna T K Sukrishna T K 2 years ago Could you please make a video of how to identify the genes promoter region and methylation status in the promoter regions by different software? AKHIL AKHIL 1 year ago Would you please explain what is the MBD2 protein size, binding/active sites and how many DNA probes can binde with one MBD2 protein..?? Oluchi S. Oluchi S. 5 years ago I find this video very useful. I now understand the topic better. Thank you Kholoud Shaban Kholoud Shaban 4 years ago hi how can we download these slides for studying ? i can not find them in the website mentioned above thank you Sweta Sagarika Amanta Sweta Sagarika Amanta 2 years ago Lecture was so helpful. Thank you sir. 1 nitin challa nitin challa 3 years ago !!!!! Thank you so much, Sir, this helped me a lot!!!!! 2 Manoj Behera Manoj Behera 3 years ago Thank u sir.very well explained Lili S Lili S 7 years ago Beautifully explain, thank you! :) Preet Kaur Preet Kaur 2 years ago I would like to thank you for the video, which saved my darn important time. saw your video and then did a quick reading... the concept is clear. Thanks, thanks thanks 2 Shomu's Biology Vishal Saroj Vishal Saroj 2 years ago You are really born to solve life science problems. Thanku 1 Kaushani Chanda Kaushani Chanda 1 year ago Can you please make a video on dna methylation in bacterium (prevention of self dna from restriction enzymes) yolande lee yolande lee 7 years ago very helpful. thank you for uploading. Stephen Leighton Stephen Leighton 2 weeks ago Question..... can anyone explain or give clarity on the following ... does any change to typical Purine & Pyrimidine, folate, B6 or B12 pathways during pre or early post natal periods result in heritable genetics that could be passed from that baby should they procreate in later life? Rufaro Jombe Rufaro Jombe 5 years ago Very useful video.thank you TakeMyRocket TakeMyRocket 8 years ago Is the euchromatin silencing by HP1 natural or a tumorous phenomenon? Sayani Banerjee Sayani Banerjee 7 years ago just excellent.............very much liked Veeresh Jain Veeresh Jain 3 years ago Sir plz make a video on ..... Core and minicore topic Vincent Pieterse Vincent Pieterse 5 years ago Good explanation! Neha Sharma Neha Sharma 4 years ago Thanku sr ....its vry helpful but there is little confusion dat sm CpG get methylate and sm CpG which r located near promoter & enhancer region not methylated,...? Hw is possible? Ankita Dhang Ankita Dhang 4 years ago video is too good,,thank you sir for this video.. 1 Alysi Alonso Alysi Alonso 7 years ago excellent..:) thank you Jaspreet Singh Jaspreet Singh 1 year ago very helpful sir 1 Shomu's Biology Veeresh Jain Veeresh Jain 3 years ago Plz sir make a video on ..... Core and minicore kweuig kweuig 7 years ago Methylation of CpG occurs in CpG poor regions and CpG rich regions (CpG Islands) of the DNA are seemed to be protected from methylation (Lim, Maher 2010). Please clarify if CpG are really hotspots???im confused AKHIL AKHIL 1 year ago Hi.. bro... Can you provide the references of your video..? Megha's Biology Megha's Biology 2 years ago No one can teach like you.. 1 Shomu's Biology Hadi Johni Hadi Johni 8 months ago THANK YOU SO MUCH BRO Shivani Meena Shivani Meena 7 days ago Sir! Can you make this vedio in hindi? Tonya S Tonya S 5 years ago how would this work in the Steven Avery case? Hanith Raj Hanith Raj 1 year ago Dna methylation - Turns off transcription Histone acetylation - Turns on transcription But as the Histone methylates, whether the transcription turned on or off ?? What happens when histone prtn methylates?? SUBASH CHANDRA SUBASH CHANDRA 4 years ago Explain how DNA methylation is passed on to daughter cells. Fariha Jutt Fariha Jutt 6 years ago thanku sir :) <3 2 amrutha menoky amrutha menoky 7 years ago thank u sir............................ Sunny Yoda Sunny Yoda 4 years ago I can't find the ppt for this lecture Vivek Gadge Vivek Gadge 7 months ago Why METHYLATION TAKEN IN 5 carbon position of cytosine, and why not it taken on other nucleotides bases Ok Ok Ok Ok 4 months ago U are best teacher 1 Shomu's Biology Ali Alsaeed Ali Alsaeed 3 years ago This is difficult and complex 😣 1 Ameerhamza Rind Ameerhamza Rind 1 year ago Sir please Indian English bolne se acha hy Hindi mein he lecture deliver karein. giang phạm ngân giang phạm ngân 5 years ago Who can help me way to download the ppt in this video bo nk bo nk 1 year ago Read this pls..i just took a tetanus vaccine and it has differential extraction-methylation CAN THIS CHANGE MY DNA ? 1 Željko M. Svedružić Željko M. Svedružić 1 year ago it is all OK, except that DNA metaylation :-) should be DNA methylation 2 Kuldeep 's Biology Kuldeep 's Biology 4 years ago Wow nice video. . 1 pawankumar thakur pawankumar thakur 5 years ago really great...its vrey usefull giang phạm ngân giang phạm ngân 5 years ago how to download this ppt? please Óscar G. Rodríguez A. Óscar G. Rodríguez A. 6 years ago i can not find this material in the web page, can you help me? Christina Georgalas Christina Georgalas 6 years ago God damn this is one long video haha 2 PARTHA PROTIM CHAKRABORTY PARTHA PROTIM CHAKRABORTY 6 years ago so long explntn..can u plz a share a short video about it Yakgang Yakgang 7 years ago I love you Suman, that is all. Shibu Paswan Shibu Paswan 3 months ago Please sir Hindi me vedio banaya kijiye Ali Alsaeed Ali Alsaeed 3 years ago This is difficult and complex 😣