How bacteria "talk" - Bonnie Bassler 466,028 viewsFeb 9, 2013

How bacteria "talk" - Bonnie Bassler 466,028 viewsFeb 9, 2013 TED-Ed 16.7M subscribers View full lesson: http://ed.ted.com/lessons/how-bacteri... Bonnie Bassler discovered that bacteria "talk" to each other, using a chemical language that lets them coordinate defense and mount attacks. The find has stunning implications for medicine, industry -- and our understanding of ourselves. Talk by Bonnie Bassler. Chapters Humans? 1:00 A Potpourri of Notorious Bacteria 2:20 Vibrio fischeri Communication 4:15 Bacterial Quorum Sensing 7:16 Intra-Species Communication 9:12 Bacterial Communities 10:14 397 Comments rongmaw lin Add a comment... Lili Lili 2 years ago Timestamps/vocab: Vibrio Fischeri- 3:09 Bioluminescence- 4:09 Quorum sensing- 7:13 Intraspecies communication- 9:18 Interspecies communication- 10:49 Esperanto/ a universal communication molecule- 11:31 A new approach to antibiotics- 13:45 Quorum sensing in bacteria- 14:43 The gang- 17:11 255 Evan Palmer Evan Palmer 5 years ago That was one of the best explained TED talks I've ever heard 323 Kaitlin Matrix Kaitlin Matrix 2 months ago The way she speaks about the young researchers is amazing. Genuinely made me tear up! I don't know what I'd do if my PI talked about me like this 15 Open School Open School 8 years ago Ms. Bonnie Bassler gives one of the riveting talk about how Bacteria communicate with each, a study that will propel the future of medicine. This is one of the finest studies ever conducted and hats off to the Princeton team of young innovators. 127 Mabel Speaks Mabel Speaks 1 year ago Thank you for attributing the students who are doing this important work. So often the students who do research as part of a class don’t know that other students are being directed and taught by amazing instructors-some of whom- may not be as diligent about honoring them early on. 10 Gopika P J Gopika P J 6 years ago i love the way she present the topic, it makes curiosity in learning about that subject. 108 Mien Trant Mien Trant 1 year ago Not just the great information she gave but also how incredible she talked smoothly energetic non-stop in the whole speech. 18 Josh Erkman Josh Erkman 4 years ago (edited) Its the twentieth century and our most breakthrough discoveries are still happening because we saw a light. Excellent research, groundbreaking discovery and I hope what will be the foundation of our medical treatment of the future. 15 Fernando Artiles Fernando Artiles 4 years ago Amazing! A very passionate scientist, an incredible and enthusiastic teacher! A "must see"! 7 David Thompson David Thompson 8 years ago Fascinating subject. Brilliant speaker. 52 fast2hemel1 fast2hemel1 1 month ago beautifully articulated and amazing persona !! thank you for doing what you do. Rachel citizen Rachel citizen 3 years ago Wow!! What a fantastic presenter and she explains it so clearly. Excellent. Thank you heaps for the upload. 2 DIEGO FERNANDO ECHEVERRI GARCA DIEGO FERNANDO ECHEVERRI GARCA 11 days ago Prof. Bonnie Bassler and team, thanks a lot for your excellent presentation. Is there any evidence or examples of these "communication molecules" in processes (digestion, immunity, vitamin synthesis etc) mediated by the human microbiome? thanks! lillazyboi lillazyboi 6 years ago My question is: Just like how bacteria can build resistance to antibiotics, can they also counter the quorum sensing block? Bacteria are very smart 41 JackSparrow JackSparrow 1 year ago (edited) Everything about this speech was superb. I really enjoyed everything she had to say. Really was one of the most entertaining talks that I actually really liked. Oliver Little Oliver Little 1 year ago She adapted the Dazed & Confused quote: "Thats the awesome thing about high school girls; as I get older, they stay the same age". Fantastic speech Ms Bassler! 7 Valerie Pallaoro Valerie Pallaoro 3 months ago I love the conclusion; that the conversation can go both ways. Her team are developing both - away to stop bacteria from talking to each other (protect us from them) and a way to encourage their conversationability (protect them from us) It could so easily have just gone the one way. Nicely done. And much appreciated. Joe Maciarz Joe Maciarz 9 years ago I got excited about this just from listening to Bonnie talk about it. At first I thought she was nervous, but then I realized it was just her and her excitement for her subject. And her down-to-Earth analogies made it incredibly easy to understand. Thanks so much for sharing this presentation. I learned a lot! 1 Anraí Duine Anraí Duine 5 years ago Man that symbiosis with the squid is just wild!! 128 Cathy Sissens Cathy Sissens 1 year ago Phenomenal speech! Beautifully explained and riveting! Had me hooked from the intro... 2 Dilliganesh .M. Dilliganesh .M. 3 years ago Your lecture is soo energetic. I felt learning something new. Your talk is very informative and it's amazing discovery. 2 Justin Macklin Justin Macklin 4 years ago Fantastic video!! I love the way bonnie describes things. Euneil Labrador Euneil Labrador 3 years ago I am currently learning this in my Microbial Biotechnology class. She made this topic more interesting for me to understand! <3 Alek Alek 9 years ago awesome. i love the metaphors you can draw from knowledge about bacterial systems ShallowBeThyGames ShallowBeThyGames 9 years ago Never thought of other "friendly" bacteria, always thought that "probiotic" stuff, while having an element of validity was blown out of proportion regarding it's benefits. Suppose I should do a little research on it, starting to find this whole immunology and virology quite interesting. Thank you very much for setting me straight. Zach Rawlings Zach Rawlings 2 months ago Soo many interesting facets of this talk. Love it Larry Chang Larry Chang 9 years ago Wonderful presentation on so many levels. Naturally, the ones i focus on demonstrate the PANACEA system: the idea of independent holons that make up a holarchies, data exchange, cooperation and emergent effects. The sovereignty of bacterial communities is recognized and a NPV index is assigned to them. (Don't envy who has to count them.) Karen Corkery Karen Corkery 3 years ago Fascinating how Bonnie can initiate such excitement and curiosity about cellular structure and their existence. Makes me hungry for more. Omar kmt Omar kmt 4 years ago great talk enjoyed her enthusiasm and the valuable information and the advancements they achieved Abominatrix650 Abominatrix650 5 years ago I have to do an essay on bacterial biofilms and communication plays a big part of it. This video is great at helping me! 1 Charmaine Kue Seguro Charmaine Kue Seguro 1 year ago (edited) Really interesting talk! Excellent speaker as well. Would love her to be one of my microbio professors. racekarts racekarts 1 year ago A super excellent talk Bonnie, thank you syncflame syncflame 2 years ago Here I am sitting in micro class, imagining bacteria sharing memes :D 48 Patrick Faas Patrick Faas 6 years ago Bonnie Bassler is wonderful. 44 Romaissa Ch Romaissa Ch 4 years ago very interesting! simple but fascinating. there will be always new powerful pathogenic bacteria but there will be also new powerful solutions.I think that would lead to new discoveries and treatments. vevo ro vevo ro 7 years ago Mind is blown love this stuff! 7 Carol Radway Carol Radway 7 years ago Wonderful, mind expanding talk. Muhammad Siddique Afridi Muhammad Siddique Afridi 3 years ago You know what last night I was reading about quorum sensing and read many kinds of stuff to get know about that but in vain, and yes now I got to know what quorum sensing is exactly. thanks for such a mesmerizing way of your explanation 1 guyinthewhiteT guyinthewhiteT 9 years ago This is beyond awesome. It makes me feel fuzzy inside. Maybe it's the bacteria. Michelle Williams Michelle Williams 1 year ago Her passion is so inspiring!!! wjestick wjestick 8 years ago It would be interesting to research how our immune system, and our gut flora utilise quorum sensing to protect themselves. This would be a good idea before we try to "help" our bodies to work better. Adding quorum sensing (like most other drugs) has the potential for unintended consequences. Rather like antibiotics that killed our gut flora causing yeast infections, cancers, autism and many other conditions. 4 S.L H. S.L H. 9 years ago Great talk , best Ted-ed i have seen .And they are all pretty amazing. squidb8 squidb8 8 years ago So if we tamper with inter-species communication, would that affect beneficial bacteria also? 12 porculizador porculizador 8 years ago i think kary mullis' molecule approach to killing bacteria is the best way to compensate for the demise of antibiotics but this research on how bacteria communicates is amazing and very promising too salahhe Sali salahhe Sali 9 years ago One of the best Ted's. Good job! Veronica Malmström Veronica Malmström 2 years ago Wow. I am a few years late to this video but this was one of the most interesting videos Ive come across on youtube. She is fantastic. Hailey Wilson Hailey Wilson 1 year ago That was the best TED talk I've ever heard LionTheHeart LionTheHeart 1 year ago This lovely intelligent lady is definitely in the right career. Fascinating! Thank you Sandi De Guzman Sandi De Guzman 1 year ago Are you able to provide a list of what type of bacteria you tested for behavioral modifications when trying to find a different approach to reaching a vaccine? Alexander Borsi Alexander Borsi 9 years ago If half of the teachers in this country were like her, I have no doubt that we wouldn't be falling behind on our education scores. Hien Nguyen Hien Nguyen 9 years ago You can tell she's an experienced lecturer. H S H S 3 years ago I got so touched at the end when she recognised her brilliant "gangs". People sometimes forget to acknowledge but she didn't. 1 Semanur Doğan Semanur Doğan 2 years ago Would you add Turkish subtitles to this video a very useful conversation everyone should benefit from this information. 1 nathan hasbani nathan hasbani 3 years ago Very interesting and such an articulate speaker fractalico fractalico 4 years ago Lady, you are brilliant and charming...you explained so graciously a fascinating and profound aspect of life! KITTEN for BUNNY KITTEN for BUNNY 6 years ago Absolutely f'ing excellent talk!!!!!!!!! 34 Rohita Muthuvelu Rohita Muthuvelu 3 months ago I'm really surprised this isn't more famous, it's so cool!! Brian Foley Brian Foley 8 months ago I've seen Prof. Bassler on another You Tube channel....she's brilliant. Leon Harvey Leon Harvey 4 years ago That was an awesome talk!! 2nd3rd1st 2nd3rd1st 9 years ago You're forgetting the other 50 procent of the equation: the students. I had some great teachers but despite that 4 of my classmates dropped out of school. You can't blame the fox for drowning the scorpion when the scorpion stung the fox first. S.S. Daud S.S. Daud 6 years ago Great for a understanding, knowledge on the Bacteria and works good for a basic understanding the most important living beings that bless and trouble you by being around you. X X 9 years ago Great talk in my opinion. I don't think she tried to make bacteria seem more amazing than they are, its just her over-enthousiasm that kicked in along the talk. Dont judge her for this - this is about the amazing discovery she explains about. Aidan O'Keeffe Aidan O'Keeffe 3 years ago She's so clear and energetic. More science should be taught like this. 1 Brian Babulic Brian Babulic 8 months ago (edited) She is so passionate! Love it! Yasmin Azaadeh Yasmin Azaadeh 5 years ago Just when I was beginning to think anti biotic resistance would wipe us out. 9 Gamble Gamble 2 years ago What if you told them that their was enough of them to start their intensively virulent stage early, would this mean that the infection would be detected and destroyed by the immune system before the numbers became high enough for them to do significant damage? Aaliya Aaliya 1 year ago The best Ted talk ever 👏 1 Galedis Galedis 9 years ago I love this stuff. Just the idea of giving a person with a fatal bacterial disease time enough to fight it off is amazing. I could be wrong but it also seems possible to allow a person to go on living a normal life while suppressing a disease indefinitely if they couldn't beat it outright. Zaris Zaris 1 year ago (edited) attentive to the end.. awesome speaking! well done ajnjmar1 ajnjmar1 9 years ago Amazing! Well done Bonnie and well done Bonnie's gang at Princeton. D Solis D Solis 3 years ago ¡Ay Dios la amo! Debe ser un sueño ser estudiante de ella. C Frisch C Frisch 9 years ago Beautiful. Thank-you. And very interesting: stuff I never heard about ..... 2 Ibn Nayeem Ibn Nayeem 5 years ago I thought I was watching this at 1.5x speed for a second 169 Berke Hitay Berke Hitay 3 years ago 9:36 Species specifities! My favorite moment in any Ted Talk! 3 VoteForPedro VoteForPedro 9 years ago I would love to see a culture of bacteria flash mob 1 Lewis Watson-Jones Lewis Watson-Jones 9 years ago Man, I love science so much. ThatEmeraldBreeze ThatEmeraldBreeze 4 years ago Incredible, 18 mins passed sooooo quickly. So interesting! just rusty just rusty 1 year ago Absolute legend Meximagician Meximagician 9 years ago "I felt a great disturbance in the Force, as if millions of voices suddenly cried out in terror and were suddenly silenced. I fear something terrible has happened." -- going to be said after using disinfectant on kitchen sink every day. Devil_ _X Devil_ _X 3 months ago Well explained Aman Litt Aman Litt 1 year ago for how excited and passionate she was throughout the entirety of her talk, her outro was pretty meek. Thats us science nerds for ya 1 HeCtorCapitalCe HeCtorCapitalCe 9 years ago They don't always give a standing ovation, everyone chooses as (s)he wants. It's just a testimony of her speaking abilities and the riveting facts she brought forward. You can dislike any speaker and their subject, but for me this format is of so much value. Michael Brown Michael Brown 6 years ago Absolutely Awesome!!! DesertstormPT DesertstormPT 9 years ago If you (that consider yourself so enlightened on the subject) learnt 2 things from this clip in 18 minutes. Then there's learneable information in the clip, right? Maybe for someone not so "enlightened" this video contributes a whole lot more for their own knowledge. And that's more than acceptable for me. Saying a source is useless because "I" didn't learn anything from it is childish and selfish. nonchalantd nonchalantd 9 years ago I wish I could talk with my bacteria. We'd have so much to talk about. ozui ozui 9 years ago They could keep multiplying, but there isn't an infinite amount space in your body. Other microbes which have can't hurt us utilize the same space and can kill/control these other populations by starving them/taking space. That's the point of probiotics, which add microbes to your body which are benign. As for the trigger, if they're waiting for it, they're not releasing toxins. This could be buying time for doctors, allowing their patient to live an extra day for a procedure. Roxane Bidlack Roxane Bidlack 5 years ago Love this! Haripandit Paranjpe Haripandit Paranjpe 2 years ago This fantastic presentation was around 6 yrs ago but still nowhere near new line of antibiotics. Why ? 4 CJ CJ 5 months ago Would treatments that modify inter-species communication potentially affect/disrupt other bacteria? Potentially the mutualists? Patrick Sullivan Patrick Sullivan 9 days ago Einstein chose Princeton. Dr. Bonnie Bassler chose Princeton. Total geniuses. 1 Spens Spens 9 years ago wow she deserves a nobel prize if they can market this new type of anti-biotic DesertstormPT DesertstormPT 9 years ago Another possible mechanism is what Vincent W, very well said, the enzyme production trigger might be associated not only with quantity but also with density. Haitham White Haitham White 9 years ago This was awesome. Sarc Sarc 9 years ago I think there is just a misunderstanding. Yes, if you filled a room with smoke, and everyone started coughing that would not be a great analogy for quorum sensing. However, if your lungs produced smoke, and made other lungs produce smoke, and they made other lungs produce smoke, and this led to some kind of joint activity from all of the lungs, then that is analogous to quorum sensing. That is why she refers to it as a language, because the cells are producing signals that influence other cells 1 Robert Norris Robert Norris 6 years ago Fascinating out of the box thinking and obviously a unique solution, yet still applying the same logic of going to war with the bacteria which was used to invent antibiotics, which I think it's plain to see will be equally problematic down the track. Why not focus on helping the bacteria in the body which are good instead of trying to wage battle with the bad bacteria? There's quite almost infinite variations of bacteria - you really think that there isn't going to be countless strains which not only can overcome this modified Quorum sensing, but thrive off it, and in doing so, create yet again, an even worse situations for humans? Einstein said something like you can't solve problems with the same mindset that was used to create it. This is what is happening right here. 5 Semanur Doğan Semanur Doğan 2 years ago Azra Kohen mentions this speech in the last paragraph of page 243 of fi. That's great 💥 3 SomeJimmy SomeJimmy 9 years ago Give her some more time.. my heart rate's gone up! 3 Alec Chvirko Alec Chvirko 9 years ago That was fantastic. BD Home BD Home 3 years ago Respect from BANGLADESH. Thank you for such explanation. MrWillisle MrWillisle 9 years ago 11:28 What if we pump loads of that molecule into our bodies so that the bacteria will think there are way too many other bacteria and stop action? This would totally mess up their communication. OriginalCropolite OriginalCropolite 6 years ago I'm kinda confused. If they introduce the anti-quarm between some of the bacteria cells (not all.) wouldn't the cells that can talk (still talk to the other bacteria cells?); & continue to replicate exponentially? I assume the cells all need to be in agreeance in order to launch an attack? But in the time that they aren't' launching an attack, aren't they just replicating? Basically, do the cells continue to multiply if they have no confirmation of attack? Or do the anti-quarm cells completely negate any form of communication? 1 SJD SJD 9 years ago TEDtalks is the actual organisation that runs all of these lectures. This channel is an editorial of videos that are educational, so people that are interested in specific areas can get related videos. There are loads of different TED channels, but all are fed from TEDtalks. Roger Corneau Roger Corneau 9 years ago Great talk N Hietala N Hietala 9 years ago I think it would be wiser to provide the test subject / patient with the actual molecule so that the bacterium becomes virulent too soon and the body kills it, but that requires you to know that you've been exposed, the idea presented above idea works after the fact. Santiago González Benjumea Santiago González Benjumea 4 months ago Amazing talk Rebeka Lánská Rebeka Lánská 4 years ago This is so interesting! Alexander Pieman Alexander Pieman 9 years ago She doesn't relate to bacteria like "some complex animal". She doesn't say they're more important than animals. She uses expressions like "talk" to put across her message in a more fluid way, and adds some fun...nobody actually thinks bacteria talk or can think at all. She's excited because these are important scientific conclusions, understanding interaction and the game changer that is to manipulate bacteria like this. 1 qed47 qed47 9 years ago excellent argument !!! Peter K Peter K 9 years ago I thought about that too. I wonder if the infected person, even though the bacteria is "dormant", would that person be contagious and spread the bacteria to others? UvebeenHAZED UvebeenHAZED 9 years ago I'd love to have you to be my lecturer :) excellent boris 25 boris 25 1 year ago Best lecture Juan Esteban Bolivar Juan Esteban Bolivar 2 months ago Casi muero intentando traducir lo que entiendo de lo que dice en mi cabeza jaja Elon Musketeer Elon Musketeer 9 years ago There is no need to tell everyone how you cannot derive morality from bacteria. In fact, bacteria works together better than many humans do. litojonny litojonny 9 years ago i find microbiology so fucking amazing oğuz hüküm oğuz hüküm 7 years ago harika bilgiler hdb80 hdb80 2 years ago Woah, this is fascinating. ff11 ff11 9 years ago Wonderful :) Paul Bunyan Paul Bunyan 2 years ago Dr. Bassler is an amazing scientist. That said, TED talks also gave us Elizabeth Holmes. Choose wisely. ShallowBeThyGames ShallowBeThyGames 9 years ago But won't those specific bacteria keep multiplying, waiting for their trigger? I imagine having a bacterial population that is ever expanding wouldn't be too healthy for the host organism. Or is it that, if their specific trigger doesn't come, they go into meltdown? richard wilmot Ph.D richard wilmot Ph.D 3 months ago (edited) Talk to your bacteria! Negotiate with them for health. 1 Saldā Sinkope Saldā Sinkope 6 years ago A small update on the fact about the resident microbes and the human cells- It's more like 1:1 ratio between them not 1:10. 8 Connor Siebenaler Connor Siebenaler 1 year ago Amazing! Subham Sinha Subham Sinha 2 years ago Excellent video 👍👍 StrawberryStarfish78 StrawberryStarfish78 9 years ago Brilliant! Vinita Jagtap Vinita Jagtap 7 months ago Really awesome talk HeCtorCapitalCe HeCtorCapitalCe 9 years ago And btw, I will probably not forget that bacteria can communicate with each other about their population (using 2 different proteins) any time soon. Rusty Case Rusty Case 6 years ago Great presentation ! Tnx to George L. for the link ! rc 1 Jungle Jargon Jungle Jargon 9 years ago If you shut off all bacteria, that includes the good bacteria. Another thing is if you get virulent bacteria and shut them off, they are still reproducing and they still need to be eliminated. It might make more sense to build up our own imune defense system. Christopher Gilbert Christopher Gilbert 2 months ago If my eyes are just evolution then so is my consciousness? Am I just a 6' tall vehicle for bacteria? Are bacteria to blame for my ice cream cravings? This is almost like the Matrix. EHB Bish EHB Bish 5 years ago bacteria infact communities with each other .u can imagine that they plan for every attempt to attack by setting in round table. actually they did what the presenter mentioned and that makes the organ weeks and eventually its vibration lower to less than some hz which allows the bacteria to makes its planned attacks. the cure eventuality depend to increase the organ vibration by endorsing an coherent wave... equally in magnitude and opposite to its hz...... this is the law of vibration DavidTheHappenings DavidTheHappenings 7 years ago Despite their vast numbers, bacteria don't take up that much space because bacteria are far smaller than human cells. By total mass it's only about 2% of total body mass--a lot less than the 90% "shock figure" that she gives. 2 Charles Gay Charles Gay 9 years ago Unfortunatly as a teacher I can testify to the fact that many children have no imagination for science or are kinesthetic learners. So nothing would be less effective than being leactured, even by a speaker as amazing as her. Daniel J. De Jesús Daniel J. De Jesús 9 years ago This was fascinating. iBL1nK iBL1nK 9 years ago Why am i exited for this to be released as the new antibiotic?? Randall Hayes Randall Hayes 5 years ago Harrisburg University sends our thanks for the information! Alexander Borsi Alexander Borsi 9 years ago Does the painter blame the canvas for when a painting does not sell? Does the carpenter blame the tools when the work is crooked? Does the baker blame the pan when the cake turns out to be too tough? The teachers are there to INSPIRE the children to learn. There are great teachers out there, but there are also a great number of teachers who just do the minimum that the state requires and then they just blame the students when they don't have good numbers. I went though this. I experienced it. 47 - Abir 47 - Abir 3 years ago if the natural molecule of bacterial communication sit into the receptor before 'the almost replica one' that your team made..what will happened..cause it can't be told that which one will go first into the receptor.can it?? squidb8 squidb8 8 years ago I beg to differ. I think communication doesn't have to be intentional. Poker players communicate tells with nervous ticks, fighter communicate what they plan to do with how they move their bodies, but none of these two examples know that they are communicating. Dustin Ellerbe Dustin Ellerbe 2 years ago In other words.. Bacteria create life and consciousness rockinunderscore52 rockinunderscore52 9 years ago wouldnt the inter bacterial antagonist chemicals cause the bacteria within a host to also lose the ability to communicate and interact with the human cells? like all our gut bacteria would stop working BIG SHAQ BIG SHAQ 9 years ago Amazing! Tara Cheng Tara Cheng 4 years ago Fascinating! thom grunauer thom grunauer 2 years ago (edited) biology blows my mind 1 Brian Siegelwax Brian Siegelwax 6 months ago Honestly, I clicked like as soon as I saw the Mac. The rest is good enough that I've already seen this content replicated quite a few times across other channels. JD H91 JD H91 5 years ago Great video had to share. Walia Phellps Walia Phellps 5 months ago How an one cell organism could show cognitive behaviour as communication since it does not have even one single neurone? If we assume that bacteria can communicate, we must assume as well cognition and conciousness is not due to complex architecture of a bunch of neurones. This puzzles me quite a bit. Vivian Hir Vivian Hir 4 years ago What does she mean by bacteria being multicellular at the end? Does she mean in the sense that they are in groups and colonies? ShallowBeThyGames ShallowBeThyGames 9 years ago Ah, gotcha. Makes sense now then. Thanks. DesertstormPT DesertstormPT 9 years ago I did not miss your bigger point. You did mine. I do read books, search the web and watch tons of hour long documentary series and yes there's not nearly as much information on an 18 minute clip. However there's a lot of diferent ways to retain information and/or being able to integrate that information with previous or future acquired knowledge (topic too long). In any case, any thing from this 20 min clip will be more valuable than your next reality show/soap opera can offer. Anas Knbar Anas Knbar 9 months ago Do you know what’s more interesting than bacteria talk ?! It’s your talk ShallowBeThyGames ShallowBeThyGames 9 years ago This sounds backward to me, but I'm just a chump. If bacteria multiply to a point where their numbers are strong enough to attack a larger organism, why prevent them from communicating their numbers? Wouldn't it be more advantageous to encourage them, while in weaker numbers to "break cover" and then the immune system recognises them earlier and can deal with them while the advantage is on the immune system? DashaC22 DashaC22 9 years ago She reminds me of Rover Song which makes the stuff she says even more impressive :D ali fasl ali fasl 1 year ago perfect talking aureusyarara aureusyarara 9 years ago But hang on, these new-fangled quorum-sensing inhibitors don't kill the bacteria, they just prevent them from expressing the disease, not from multiplying. The second you forget to take your pill, all those bacteria will suddenly go "Oh, hello, look at all those other sister bacteria!" and start expressing virulence. It'd mean taking those meds for life! 1 Stephane K Ledan Stephane K Ledan 9 years ago Do you think WE could be the Planet's "bacteria" ? Tutankhamun18Reads Tutankhamun18Reads 9 years ago how does the bacteria know how big its host is? some bacteria xan infect a cariety of animals, but more bacteria is required to overcome a human than a mouse, so when they count enzymes they would need more. Any answers are apprechiated!!:) gus bisbal gus bisbal 9 years ago The issue is that it amkes the bacteria sound like they are responding to each other. They are not.They have no connection with each other. Its like saying when you fill a room with smoke, every one agrees to cough. You cough all on your own as a result of the concentration of smoke in your environment. There is no communication with anyone Maya Bisco Maya Bisco 1 year ago you nerds can’t just give up the answer in this instead of drooling over the talk😫 3 cazibal cazibal 2 years ago so my question is: basically its about probability right? the more signalling molecules, bigger are the chances for the receptors to link to a molecule. Given this, is it possible that within a group, a response is triggered due to population density however some cells remain with their receptors unlinked? Or the response in only triggered if ALL the cells got the memo? If so, how do they know they all got the memo and none was left out? hm Thales Silva Thales Silva 9 years ago Amazing Alexander Pieman Alexander Pieman 9 years ago The audience she's talking to isn't specialized, you wouldn't expect her to go through everything mechanically because half the people there would be lost after the third minute. Engaging them in a way like she does is pretty important for any talk like this... Dirk Broenink Dirk Broenink 9 years ago It could be that they have many other problems in there life already that you are not aware of, that is keeping them from being their true self. In my experience, anyone who is being true to their selves is naturally curious, it's a big part of humans. Hmm. I might be presumptuous here but I think the book Face to Face with Fear by Krishnananda Trobe could explain this much better than. Read a review of the book. Forgive me if I am being presumptuous. OraFN OraFN 1 year ago Who else has to watch this for biology? 1 ozui ozui 9 years ago Biochemically, not all organisms can be identified and killed by the immune system (ex: MRSA). Multi resistance is scary because we have no idea how to specifically treat it (without nuking your body and hurting many other bacteria/cells). Having something that blocks quorum sensing (talking) stops many bacteria that might be harmful by causing them not to release certain toxins or signals. lily flower lily flower 1 year ago I hope she is my microbio professor. Peter K Peter K 9 years ago First of all, this is not fake knowledge; these talks are here to enlighten us about the frontiers of science. Secondly, TED talks are not meant to teach everything there is about the subject. It's meant to engender an interest to dig deeper. I think they do a pretty good job. You can't really learn something without being interested in it. Alexander Pieman Alexander Pieman 9 years ago It's concerning that you think that way of a woman talking about bacteria, and can't see at all, ever, how it's just *expressions* which convey knowledge that she's passionate about. The subtleties... simply aren't there. These are normal ways of explaining a subject, and only serve that purpose. I'm not going to convince you at this point I see, and I don't think you're going to bring up anything new-as I'm not with this last one-so this is it for me. <3 1 Tutankhamun18Reads Tutankhamun18Reads 9 years ago yea tht makes sense! thanks :) TheaDragonSpirit TheaDragonSpirit 9 years ago I never said that. You assumed that. But she is jumping to a hell of a lot of conclusions or making a lot of metaphors to make things seem more than they are to make it interesting. But if bacteria multiplies enough times and overwhelmes the host by how much it eats they create a chemical reaction it's not really communication as she put it. That is like saying the earth is communicating with the sun. But really the bacteria is causing basic chemical reactions. It's like saying my phone alive. Nico Enerlan Nico Enerlan 2 years ago I’m doing this for Ap bio. 1 SJD SJD 9 years ago Bacterial populations are largely self limiting - they can only grow in number so far before the amount of nutrients is stretched too thin, and their waste excretion is too high (Humans will encounter something similar eventually). Some species rely on the harmful effects of their toxins to invade specific tissues and habitats within your body, meaning without they wouldn't be able to 'find a home'. What this would essentially do is neuter the bacteria, preventing disease and death. Alexander Borsi Alexander Borsi 9 years ago This is like the chicken blaming the egg. Both sides are part of the equasion, but the fact is that the teachers are responsible for inspiring the students into wanting to learn. How many times have you heard younger people saying that they are BORED at school? I hear it constantly. The fact of the matter is that schools as they are today are prepping kids for FACTORY JOBS and not the multimedia, video-game, constant access to information, cell phone, texting generation that we have now. Shane Tuballa Shane Tuballa 5 years ago can anyone help me find the journal article or scientific paper about this study? thank you. Roy Liu Roy Liu 1 year ago so the squid is kind of like the great white, because the bottom of the great white is white to mimic sunlight and the top is dark to mimic the ocean depths squidb8 squidb8 8 years ago Your right they aren't responding to others in the group, only the chemistry compared to the compared to the chemistry that is produced by the whole of the population. From whence these emanation come from these bugs probably could care less. However she isn't talking to chemist, so she has to speak more commonly, lest the crowd lose interest because they have difficulty personalizing the information. zzcaptain (Mast IV) zzcaptain (Mast IV) 3 years ago yeah, i can make my guitar "talk" too. how scientific is that? quorum sensing is not fancy, it's only a word that is not as important as it's meaning. so then if i get enough guitars together that "talk" in the same key, i should expect something like Zsa Zsa Gabor's "marvelous darling" effect. i am just not quite sure how to get the autoinducers to apply themselves. gus bisbal gus bisbal 8 years ago That is not communication in anyway. That is observation from the other party.Communication IS intent of getting a message to the other party. That is what defines it as communication. If not its actions interpreted as something through observation only. A bee does not communicate that it wants pollen by buzzing around the flower it just is trying to land, you can observe it and interpret it as an intent that it wants pollen but the bee is not communicating anything. It just wants pollen. Sea Pig Sea Pig 9 years ago This is old, but good. j parks j parks 6 years ago Such intricate behaviours and people still think it all evolved by chance. Amazing blindness. 1 lmhorowitz lmhorowitz 8 years ago How sad that you feel the need to criticize a fascinating talk Talk Nerdy To Me Talk Nerdy To Me 7 years ago The main thing that scares me about GM and GE foods is that any DNA from them that isn't denatured by our stomach acid (this can be a lot depending on the health of stomach secretions, which tend to be quite unhealthy in an Americanized diet plan) ends up being absorbed by the bacteria that inhabit our intestines. These bacteria are imperative to many processes within us, and are integral to our immune system, vitamin B and K absorption, and many more important processes. It is estimated that these gut flora have around a hundred times as many genes in aggregate as there are in the human genome. This is what you want Monsanto to be experimenting with? :-/ 5 Alexander Pieman Alexander Pieman 9 years ago Are you a person that gets irritated over little things that, taken literally, would not be right? Or an oversensitive vegan? I don't understand what's happening. There has to be something about you that makes you think this way, because this video is not convincing anyone that bacteria are little creatures with emotions, or that animals don't have feelings. It's like you're hypersensitive to things that you're waiting to complain about. Like conspiracy theorists, but not as comical (or as dumb) 1 Senan Allahverdiyev Senan Allahverdiyev 6 years ago stunning. 1 Alexander Pieman Alexander Pieman 9 years ago I don't support any war, I'm a pescetarian and am thinking of becoming a vegetarian, *for moral reasons*. Nothing is "ok", I hope all animal farms become redundant the day lab meat appears commercially. I'm convinced there are universal moral values and that we can slowly get there. I don't have a "purpose" and you weren't very close in describing me. There are indeed a lot of hypocritical things about the developed world, like how we're typing here instead of, say, providing food for someone. Colby Kinney Colby Kinney 1 year ago Holy cow she is smart! DesertstormPT DesertstormPT 9 years ago They dont. And they don't have to. They just start producing the enzymes when their number reaches a certain amount. The initial amount of enzymes may not affect the host at all. However they will keep reproducing and producing the enzyme from that point on. Neogoo123 Neogoo123 9 years ago Wow... Very cool... though I feel like I've watched this before.. Reese Freidenreich Reese Freidenreich 1 year ago alright, im doing this for school, can you help and answer these questions for me. what kind of words do bacteria make? yea thats it. 2 gus bisbal gus bisbal 8 years ago They are behaving as a colony. They are responding to stimulus but calling that language means she that she can't distinguish communal behavior from comm