How to Extend Your Lifespan with David Sinclair | IVY Masterclass

How to Extend Your Lifespan with David Sinclair | IVY Masterclass 1,001,808 viewsJan 30, 2020 IVY 19.3K subscribers Dr. David Sinclair is the world-famous geneticist behind the paradigm-shifting science being conducted at Harvard’s Center for the Biology of Aging, one of the top 50 most influential people in healthcare, and according to Time Magazine “one of the 100 most influential people in the world”. He joins IVY members for a Masterclass to discuss the science that can change the way we age and provide methods in extending our lifespans. Join us for more IVY events and speakers at http://bit.ly/ivy-yt Find more talks and information at http://bit.ly/ivy-mag-yt -- Follow us for more great insights! Facebook: http://bit.ly/ivy-facebook Instagram: http://bit.ly/ivy-ig Twitter: http://bit.ly/ivy-twitter LinkedIn: http://bit.ly/ivy-linkedin 1,450 Comments rongmaw lin Add a comment... Belinda Mayson Belinda Mayson 1 year ago I bought his book..a great read. Gives me hope at age 73, with diabetes,a heart patient with pacemaker, hypertensive,vertigo and deafness.. dreaming big of reaching a hundred years..why not? Thank you Sir David Sinclair! 572 MaxXxaM MaxXxaM 1 year ago Protect this man and all the researchers! 358 Cheryl R Leigh Cheryl R Leigh 4 months ago The main takeaway from this brilliant lecture was quality of life which to my estimation is far more important than longevity...which has its perks but not if the quality of life is poor. 15 Haxxor Pwnzor Haxxor Pwnzor 7 months ago People like David Sinclair, Aubrey de Grey, Jason Fung, Liz Parrish makes me hoenstly believe that we can say goodbye to pathetic diseases once and for all. 41 Lis Engel Lis Engel 9 months ago I love the focus on “extending health span” - and on staying curious and playfull and your optimistic message that 80 % of healthy aging is in our own hands - so now you make us curious of what we can do beyond what we already know - no smoking loving life and being active each day 39 Tarciane Dill Tarciane Dill 1 year ago I love how he makes everything easy to understand!! 115 Akimex Green Akimex Green 1 year ago I became 100% fan of this man since the first time I found him, a few months ago. I can't wait to buy his book. 28 gg GG gg GG 2 years ago Thank you Dr David Sinclair , you explain everything so well and simple I enjoy hearing all the interesting information you have for us . 72 Desi Ranks Desi Ranks 1 year ago I love the way he gets you to think pro life. Thinking like this keeps you vibrant and young at heart, mind and soul. What an amazing person. Great words of wisdom from his grandma. 60 Corina Glavan Corina Glavan 6 months ago David you are an inspiration to our generation that saw our parents spent in nursing homes. Superb belief in life and our ability to reverse ageing. Thank you! 3 Redman Crosby Redman Crosby 1 year ago David .. an amazing talk of Wisdom placed into the crucible of good science and humanity. Great to hear you talking of topics that often people do not ask .. Immortality, Joyful Longivity, Focused Happy Peaceful Living Of Life. Great book, you are a Breath Of Fresh Air 😀😀🙏🏾🙏🏾 22 Whiz Whiz 1 year ago Such a profound talk to such a small audience. That is what differentiates a true scientist from a simple talker. I wish there were more of Dr.Sinclair on YouTube. This research is most vital to humanity right now. 6 evoman1776 evoman1776 1 year ago (edited) Christopher Hitchens had a great line about dying, he said "People say the party is over when you die but it's even worse - the party's going to go on but you have to leave" That really sucks. Let's end aging by 2050. 291 SKid SKid 1 year ago World needs to know about this team and Mr. Sinclair and the work they do, this is simply amazing. 28 Jon Jones Jon Jones 2 years ago Perhaps the most significant person on the planet right now and still relatively unknown. I'm so happy this guy exists. 433 steve pope steve pope 7 months ago I have fasted for years and believe this has really helped me fight age illnesses and weight gain, I now am able to go the entire day with very low calorie , I drink natural drinks with zero calories and don't have cravings at all , I lift weights 3 to 4 times a week and spin class. Now following this plan to expand what I believe has been working for me . I even get more done when in a fasting state , including bills and important events , seems that I think clearer when properly hydrated and drinking Kambutcha type drinks etc . 7 Scott Lavoie Scott Lavoie 2 years ago Just ordered David's book and am excited to read it, I'm thankful that people like David and so many others have devoted so much of their lives to this research - I do believe this is the future of medicine. 31 cristina del rosario cristina del rosario 2 years ago Retired nurse.I love your first book.great review in biology and learning more & more about aging and why we aged. 28 S E S E 1 year ago (edited) I am grateful and thank you for your hard work also on behalf of my family, and supporting you 100% 14 Rick Kowalchuk Rick Kowalchuk 2 years ago It's great to keep learning this updated advanced knowledge! 27 Aphix Aphix 1 year ago (edited) Thanks for the insight Dr! Keep up the great job..I have learnt a whole lot of new things👍 7 DingleySquare DingleySquare 1 year ago The question "why we age?" is easy to answer when one gets to later ages. Wisdom does not necessarily arrive early in life. I am an identical twin and possibly the black sheep of the family and I have outlived a fine twin sister. Death is for those who are extremely ill or restricted and no wish to live beyond reasonable years. It all depends on one's life, on family connections and the ubiquitous wish to watch grand children etc grow up. If we have active and enquiring brains and a healthy body we can have the capacity to use our wisdom and live mentally active and positive lives beyond the norm. That is we take responsibility for our actions and create the life we want or endeavour to do so. Sadly many humans at this time do not take up the challenge of change required to continue further than the age of life expectancy, etc, etc..... I wondered how a younger person was able to talk about living longer because when he gets to his 70's, he will be faced with challenges not offered before. He will make changes in his health or life directions that might be needed and there will be enormous differences. It all boils down to what we think and feel at any particular age. And older still, I am not sure it is length that we will go for but simply enjoy quality of life and allow it to unfold. I, personally do not wish to put an age for future death however I am sure there is more for me to learn and achieve if I choose to acquire the mindset needed to further new wishes, dreams, goals - whatever. We age and die because it would appear to be a universal law of human nature. The differences between the young and the older persons are many and create many misunderstandings. The world needs new minds to let go of old (no longer of use) values to make way for the new (not necessarily better) values of the young. Death like Winter is the natural way of things. Long live Spring. 25 Joan Campagna Joan Campagna 11 months ago This is amazing to learn so much about aging from David Sinclair. A great scientist 5 Jordan Ong Jordan Ong 1 year ago David Sinclair, you are the greatest scientist and a legend. I would be honored to join you to find a youth cure for everybody once and for all. 48 Anthony Tindle Anthony Tindle 11 months ago Great talks yes we all want to live healthier but without all the hard work to achieve this without all the costly surgery to be 20 years younger save this man he is our fountain of youth. 3 Ajay Kumar A Ajay Kumar A 11 months ago Thank you very much Sir for sharing your great research knowledge on longevity! 3 Lucy Young Lucy Young 4 months ago Dr David Senclair highly professional, best lecture in human health and to live healthy long life, God 🙏😊 bless Dr David Senclair the people in the world 🌎 that can access all his lectures are knowledgeable and listenable informative lectures, thanks 😊👍 Dr David Senclair 3 jami Goss jami Goss 1 year ago Bravo! Not ready to give up on my antioxidants, but love your hypothesis! Please give your audience microphones or repeat their questions. Thank you. 14 orbitalframe13 orbitalframe13 10 months ago Big Fan of Sinclair..hes really good to listen and to learn from 4 Adonai Blackwood Adonai Blackwood 8 months ago Divine healing. Divine health. Divine Life! 💛 1 Steven Fenster Steven Fenster 6 months ago Sinclair's brilliance comes from having asked the questions as to why we age, and if we can address that. Alice Verberne Alice Verberne 2 years ago One hour 46 minutes in, you get the cherry on top of the cake. Incredibly motivating. 21 alexandria nguyen alexandria nguyen 1 year ago Excellent class . Very educational, very informative. 7 Iggy Perrelli Iggy Perrelli 5 months ago Legend has it that David is actually 80 years old. Very fascinating talk. Thank you 2 Endo Endo 2 years ago 1. Eat fewer than three meals a day. 2. Lose your breath from exercise. 3. Get a standing desk. 4. Do hip-hinge exercises. 5. Use biomarker feedback. 6. Sleep well. Reduce stress. 7. Never lie. 104 Kayce Crews Kayce Crews 1 year ago (edited) I don't agree with everything he says, but his audiobook "LifeSpan" is very good and read by him. I got the audiobook so I could listen to it several times. It's a lot to take in. 36 Maria Marinho Edgell Maria Marinho Edgell 1 year ago Beautiful book, I loved it ! 4 Peter Cyr Peter Cyr 1 year ago This really is great. His insights would be improved by talking more to Peter Atia (who he mentioned), Ivor Cummins and Andreus Einfeldt among others who study healthspan. 10 autumn1231 autumn1231 8 months ago 3 minutes into this. I'm 65 and have an 11 year old son. He's such a wonderful person and I don't want to leave him when he's so young. I need at least another 20 years with him. Hoping to get some great information here. 2 mosuutjuh mosuutjuh 11 months ago Great lecture. Thank you! Kailey Green Kailey Green 1 year ago David Sinclair, you are the greatest scientist and a legend. I would be honored to join you to find a youth cure for everybody once and for all. 10 Road Runner Road Runner 1 year ago (edited) I’m 72 and just came back from my 6 mo check up with my Dr. She asked what I was doing to have such a 100% good analysis. I am on NO medication. Have no medical issues what so ever. #1 live like an ostrich ...head in sand..don’t focus on world events, news, etc. Avoid negative thoughts and negative people. #2 eat like a rabbit..more veggies than fruit or meat, fast at least 16 hours a day, no processed food #3 keep moving, don’t be a couch potato, get up and DO something everyday 146 David Kirk David Kirk 7 months ago Love everything this guy is about. Honestly I don't see big pharma and others that are in control will allow him to get far. Anything that "cures" will never exist. Doesn't bring in as much money and that's what it's all about. 1 Laurie Baker Laurie Baker 1 year ago He has a greatertude for a healthy sound life just love his teaching. 5 Damien Damien 1 year ago The last 2 years I have been water fasting one week every quarter, that has helped tremendously with everything and I think aging too. 15 Redman Crosby Redman Crosby 1 year ago David, again a great dialogue. One thing I would importantly add is One's Intent!!. Intent = Outcome.. Those who's intent is to live longer Will.. Those who want a pill Won't.😊😊 3 mary nelliyattu mary nelliyattu 1 year ago Thanks for the extraordinary and still practical points for bettering health.I have been trying to follow your valuable and evidenced tips for sometime tips. One clarification,is it okay do intermittent fasting from 2pm to 8am next day. 1 Troy Smith Troy Smith 1 year ago Very interesting Dr. Sinclair, I was always as a child believing that we could live much longer and I found out that there is a type of star that has its jet poles facing directly towards us shooting accelerated particulars destroying our DNA. I'm wondering if you know of this and how this star effects our DNA? 1 Liza Tam Liza Tam 1 year ago Dr Sinclair, I hope to invite you to our conference in Canada ! You completely open our eyes and I strongly believe the protocol you bring forward can slow down aging. How can I get in touch with you. 1 john lucich john lucich 9 months ago I don’t have a PhD, or a PhD capable brain, but my mind can Understand & Comprehend Dr Sinclair’s theories because he is also a great teacher ! 4 Tryllium T Tryllium T 2 years ago Thank you Dr Sinclair - very good info! 9 Adeel Khan Adeel Khan 1 year ago 12:50 I've asked a number of folks if they'd like to live indefinitely (over a number of years). The answers are heavily dependent upon the quality of life experienced. The way the individual looks at the world, also determines how they look at issues of life and also death. 9 Arlene Portsmouth Arlene Portsmouth 1 year ago My favorite part about this lecture is at 1 minute and 30 seconds after he takes a quick sip of his red wine and places the cup down; " I'll tell you what, if it doesn't make me live longer if sure makes me feel grateful to be alive!" 😂 almost makes me want to pop open a bottle of Resveratrol on the shelf behind me! 4 Creepy Girl Creepy Girl 2 years ago Excellent talk! David Sinclair never gets "old" ;) 4 Modern Gnosticism Modern Gnosticism 1 year ago As right now human society is not ready for its humans to live longer than 100 but as everything in time mentality will change, great minds will live also longer to guide humanity to a better way of living. Therefore it should be an individual decision. Thank you David. Bliss WKC Bliss WKC 10 months ago Thank y'all so much dearest 🌹 Y'all such an inspiration 🥰 Appreciate y'all from the bottom of my heart 💖 Be Blissful Eternally 🙏👼🌈 Kenneth Henrik Olsen Kenneth Henrik Olsen 1 year ago (edited) i love this man ! Very good. his brain is a diamond . 49:30 It appears the nerve cells grow in a C-shape, then short circuiting on its own path, then moves away from itself, then there is a clumping back and forth on the nerve path. and a new split appears about middle of the initial C shape . 4 Kyle Medina Kyle Medina 5 months ago (edited) 1:00:00 List of lifestyle habits to extend lifespan 1:11:49 Raise NAD levels by exercising, being hungry, or taking molecules that raise NAD (NMN) 1:13:53 mTOR activity is reduced when protein is detected 1:17:16 Lifestyle of people who tend to live longer 1:21:33 Taking resveratrol (thing from red wine that leads to longer life) as a supplement 59 Adeel Khan Adeel Khan 1 year ago Question : Can we reverse ageing in a targeted spot? Like hair follicles, knees, other joints, organs etc. 3 Cesco Cesco 1 year ago Thank you David, I am grateful from the heart 7 Sangita Sarmin Katun Sangita Sarmin Katun 1 year ago David Sinclair, you are the greatest scientist and a legend. I would be honored to join you to find a youth cure for everybody once and for all. 3 dikeledi mogobe dikeledi mogobe 1 year ago (edited) This guy is deep! Genius! I respect him! 34 Michael Michnya Michael Michnya 1 year ago I'm with Woody Allen on this. I hope to live long enough for science to figure out a cure for death. And I want to be healthy all the way through. There's plenty to be curious about. 9 Ann LoPinto Ann LoPinto 4 months ago Awesome, thank you 4 all this good health info, much appreciated! Keep up the good work, ur Amazing! Mukesh Maharjan Mukesh Maharjan 1 year ago Its amazing... these findings can change the world ! One thing is, almost all of the findings in his talk is already being practiced for thousands of years in the east... fasting, cold sauna, resveratrol containing diet ... and they do not talk much about those life styles ... may be they do not know much about this life style... Just a thought ! 10 bill stephens bill stephens 1 year ago Bernando LaPallo ( 1901?-2015) made it to about 114years old while remaining healthy and alert, he walked everyday. Actress: Lee Chamberlin was his daughter. Another Supercentenarian Richard Overton, 112 (1906-- 2018), U.S. war II veteran that walked daily and enjoyed a cigar while sitting on his front porch and on occasion would have a shot of Whiskey mixed with Coca-Cola. He was listed at the time as the oldest living U.S. war veteran. 3 Melissa Clemons Melissa Clemons 10 months ago have lobsters been studied in regards to aging? Some of them get over 200 years old when not picked off to be served in a roll. What ultimately kills them is getting too tired to keep molting their shell (which I guess is aging, but it's not because their heart stops, etc.). 5 48peon 48peon 1 year ago Love I.F. and Clean Keto. Do 72 hours fast twice a month. My liver no longer hurts and liver enzymes back to normal. OMAD the rest of the month with a few 48 in the same month. Typically always follow a 72 hr fast with a 48 hr fast. 5 days, 2 meals. 6 Adeel Khan Adeel Khan 1 year ago 16:07 Yes. I was actually thinking about this. I understand that Mr. Sinclair is working with some economists. Just hope that this doesn't take his focus away from his main research. Overall, it's a very important question. The first time I heard about this was via Dr. Craig Venter. I believe. Say, we have the therapies and they are highly effective and super safe. Who gets the therapies, why and what will happen to the ecology if x or xx percentage of the population lives to xxx years. Maybe Safa Mohtehsharrei can help us build different models. He worked on a model that is known as HANDY, I believe. I forget what that stands for. 3 Soumya Ripan Soumya Ripan 9 months ago I wanna live more than 150 years healthy. Love how openly david discuss his research to public. 1 KETO Diamond Channel KETO Diamond Channel 6 months ago I've been keto for over 4 yrs now. It's healed so much of my body and I have had the joy of helping others get off all their meds (with doc approval) and feel so much younger and healthier. 5 unknown unknown unknown unknown 1 year ago When he was asking about living longer /immortality...people dont seem to realize it doesn't mean you can't die in other ways, just aging. Like living longer because medicine can fight off infection and such. 1 Farsh M. Farsh M. 1 year ago Dr. Sinclair is my hero! 5 lara singh lara singh 1 year ago Also I see many people with no wish to live longer but at the same time I come across people who want to live longer for various reasons one of them being to be able to continue doing what they are doing currently because they definitely enjoy it and want to continue pursuing it 1 Yann Toole Yann Toole 1 year ago David Sinclair is actually a pretty decent comedian 😊 5 Elvira Pous Elvira Pous 1 year ago Very interesting! Just that it's a pity that all the diagrams and photos that were projected were not showing well, because there was a lot of light in the room. 10 lara singh lara singh 1 year ago But I think having the option to live or not to live at certain point in time is important so that we have more space for people who actually have a will to live their life. Katarzyna Hansen Katarzyna Hansen 1 year ago We are taking NMN and resveratrol since we read David Sinclair's book and we feel amazing. 3 chickensandw1tch chickensandw1tch 1 year ago This is the best detailed description of the horvath clock so far 💯 7 Adeel Khan Adeel Khan 1 year ago 28:23 I havent had a chance to read the book. So it's great that you wrote the book. Also, thinking, Dr. Peter Attia can handle the 'What do I do right now' side of things. Because, what if between the economics and questions like these, someone may be skillfully trying to keep your focus away/distracted. Also, another thought: More people interested in learning about a) longevity and b) about newer forms of therapies c) The gap widening (>65 vs <5) would translate into lots more interest in this area overall. KenuKir KenuKir 2 years ago I recently (just a week ago) started supplementing with NMN a RES, so I take 350mg of NMN and 250mg of Res, I found my performance in gym to be noticeably increased, I also tend to need less sleep, just today I have my blood work and found all to be normal except for my elevated CRP level which jumped from 0.09 to almost 6. I have read some researches that NMN may have a side effect of promoting growth of tumour and senescence cells has anybody experienced something same ? 6 Rui-9-CS Rui-9-CS 1 year ago amazing video, very educative Billie Mann Billie Mann 2 years ago Being a fan of Sinclair withstanding, as a scientist explaining things to people he should do it better. He says " there will be better energy better blood flow". A lot of bad for you drugs and or regular supplements that harm can give you better energy and better blood flow so he should follow that up with what makes that different and not dangerous near or long term. 2 Gym Tuppernation Gym Tuppernation 8 months ago The freedom to choose how long you live must surely come with the disclaimer that we as humans, must limit how many children we each have. We already have a population problem 2 Mel View Mel View 1 year ago I love how this scientist likes to drink wine, gin & tonics !! For all of us, who can drink and not give alcohol a bad rap by drinking responsible, cheers!! Drinking, is or should be for “pleasure” only and To relax, I can believe how red wine would work for anti-aging or longevity! 9 Jahlive69 Jahlive69 6 months ago Just ordered some trans-resveratrol from Amazon, hopefully I selected a good brand. Love his talks. ❤️ 1 Michael Workman Michael Workman 9 months ago Woody Allen: “I don’t want to be immortalised through my work. I want to be immortalised by not dying.” 7 atterol jones atterol jones 8 months ago When this guy is older he may well realize the folly of his work. Anything is possible when you are not old. 3 Aatif Azio Aatif Azio 1 year ago See Science have proved the idea of ISLAM. 30 days of fasting. Now people are practicing even 7 days without a food which is amazing control. After listening to this genius David Sinclair, i have come to the conclusion that over eating is the key people are sick in modern world with too many gathering of catering, parties and food all the time and they never leave their bodies to feel hunger. Excellent i hope you overcome aged spans and humans are remain young and youthful due to your contributions in this regard. love from Pakistan :) 1 Awake2Truth Awake2Truth 1 year ago Dr. Jason Fung on fasting--very helpful. I've done up to 10 days water fasting. Not easy but possible. 20 Rabindra Khatiwada Rabindra Khatiwada 1 year ago if david sinclair explain in terms of molecular biology than that would be great 5 Nyan Prater Jr Nyan Prater Jr 9 months ago (edited) 23:27, "... don't give me what's natural." Great point, among many! 2 john lucich john lucich 9 months ago The real miracle of life, is that ordinary people can stand on the shoulder of Giants . . Like Dr David Sinclair . . And then grow exponentially ! ? 3 unknown unknown unknown unknown 1 year ago Decades ago I heard that the average life expectancy increases as the age women wait to get pregnant has increased due becoming career driven. Even a study was done putting off mating of house flies till they bred one that lived like 7x longer. 1 Harold Horton Harold Horton 7 months ago This is the best detailed description of the horvath clock so far ! Aurora Sanchez Aurora Sanchez 1 year ago Wow. Thanks for sharing your knowledge, 4 Kenneth Henrik Olsen Kenneth Henrik Olsen 1 year ago (edited) The cells are autonomous machines. They need food, to function . That is life . Vote David Sinclair for Nobel price in medical advancement . 17 Rafilover 7 Rafilover 7 2 years ago Thank you Dr.❣..very very interesting!! 11 Robot Mechanical Whiz Kid Robot Mechanical Whiz Kid 1 year ago These are the type of people most should be admiring not hollywood actors or the Kardashians... 303 nycinstyle nycinstyle 9 months ago (edited) The most effective way to enjoy life being healthy for as many years as possible is to exercise regularly and eat healthy. Seriously. Jack Lalanne had it right over a century ago. Even this guy will agree, I bet. Exercise most everyday, eat healthy, get enough sleep, have interests in life and people you can be with and communicate with who you love and care about. Do things that help others. You will live and keep living as long as possible. N1mBUS Music N1mBUS Music 1 year ago I think also hot water/tea is super important. soothing and healing action for the organs. can't be understated. 12 hew195050 hew195050 6 months ago Classic science guy. If it looks good in a lab then let's reduce it to a few simple rules and more pharmacueticals. Haitchpeasauce Haitchpeasauce 2 years ago Excellent drawings Dr Sinclair. 4 Shirley Buchanan Shirley Buchanan 11 months ago What's the title of your book. Thank you for giving us such information. Valart VALERIE HOPE BENNETT Valart VALERIE HOPE BENNETT 1 year ago thank you with all my heart be blessed. 15 MrGet MrGet 9 months ago (edited) Well from what I know drinking a glass of a red wine each and every day will kill you sooner than smoking cigarettes. Doctor with 30yrs of hospital experience told me a story of a woman in her 30s which was drinking 1 and only 1 beer (in Poland where this took place that is a bit more than a glass but still not much - half a liter) each and every day since she started her studies, and after 15 years her liver was trashed and she had to have a transplant. She also mentioned France as a capitol of liver transplants as they have the most developed culture of drinking wine. Furthermore that is developing a drinking habit. What the doctor mentioned above said is that one must have at least 2 full days a week without any alcohol to let the liver heal. If you know better - please correct me. My NMN Experiment My NMN Experiment 2 years ago another great presentation. 9 Dasitmane Ayylmao Dasitmane Ayylmao 1 year ago Have always thought of ending it because it’ll happen anyway, but this guy makes it not an option. Have to hold on the longest I can. 2 Kimberly Oz Kimberly Oz 2 years ago Ordered his book. Can’t wait to get it! 3 Lucas Crane Lucas Crane 2 years ago Brilliantly structured and delivered speech. From concepts to details with seamless fluidity. This man is not simply a genius, but a fervent believer in Humanity and masterful communicator. 3 Sara Sara 1 year ago (edited) I'm 44 and I see that people around me are always trying to make me feel old... so I'm forced to age 😓 I try to keep young but over and over I go out and every negative people around always there to step on me and my dreams... I should make a documentary! People are so horrible and don't let you live! Beyond a certain age... that is why I think rich people also means for humans to live in gated communities, and love the VIP and secluded luxury. No one catches a bus ride downtown, especially in ISA or Europe. Part of being rich to humans is being away from the main steam. Honestly, people will crush anyone who seems to be ahead of them, and it's actually encouraged in the lower classes... 😪 I honestly am happy now I wear a mask.. 4 Dave Yost Dave Yost 1 year ago It would be wonderful if you would make another version of this video that uses his presentation directly, with an insert of him at left. 6 Adeel Khan Adeel Khan 1 year ago Great! I am going to watch this video a couple of times! 3 Adeel Khan Adeel Khan 1 year ago 7:28 Cells must have a clock. Telomere may be just one part of the equation. From the perspective of evolution, life continues on. Keeps making copies of itself. In animals, as a baby is born, it's cellular clock is somehow set back to 0. For animals who's cellular clock is not set to zero (pretty much every animal), the cells in their body begin losing their clockwork. So there are more and more errors in copying information over. Like in Dr. Sinclair's other interview with the Verasitim (spelling). The individual was asking why they have hair growing on their back and ears. And it's because the body is beginning to make errors while copying information over. Now if there are specific genes that indeed do regulate ageing, then the algorithm that drives the cellular clockwork, these algorithms have to be understood properly. Next, the problem is how to reprogram all of the tens of trillions of cells in the body. So we may have a couple of different approaches in the future. 1 Keith James Keith James 2 years ago (edited) I have been following the top Aging scientists for decades, and researching the field. I started the regimen that Dave recommended a few years back. Resveratrol, NMN, and Metformin. Not sure if it is working, but friends and family say I look young for my age, and I am Dave's age = 50. Hopefully I can hold on until the breakthroughs happen... 16 The Roaming Gnome...Glenn Munro! VRCM/SkyWarn The Roaming Gnome...Glenn Munro! VRCM/SkyWarn 1 year ago (edited) The eye forms about 28 days of gestation. I fasted for about 30 days and my eyesight improved to almost perfect. That was my reason for doing it. I thought....hey. I'll just fast for a month. And eat greens and citruses and get sun exposure. See if my eyesight improves and my hair grows faster. I do this every year or two when my body is in rough shape. Then I dialed in my greens and citrus intake. Got more sun.... And increased my body temperature. And involved full body movements. But when I go long term fasting... I notice improvements. And look younger. Find the balance between bowel transit time and nutrient intake. Moderate sun exposure is useful as well. Sweating... Sleep.... I don't drink coffee ...or tea. Smoke. Nor alcohol. I've tried it... It interferes with my nervous system and makes me feel sick. And intolerable to sun exposure. I don't like dairy or eating animals either. I've tried it... I'm 50 too. And when I don't eat but every two days my ability to run long distances increases. I enjoy sun exposure...avoid coffee,tea. Alcohol. Smoking. Milk. Anything processed or cooked and definitely nothing in a can or microwaved. This will help you be more tolerable of Sun Exposure. And extreme temperature changes. I eat a lot of raw greens.... And skinny dip in winter weather ... When Im at my peak bio markers. And live on or near nudist colonies.. I eat every other day....raw greens and citruses. 1 Delia Ocampo Delia Ocampo 1 year ago When a person takes care of self positive thinker contented in life that is no worries eat healthy and exercise look younger 🇸🇽🇺🇸 9 lara singh lara singh 1 year ago I understand that this will help a lot of people but at the same time we must keep in mind that the population is growing rapidly as well and the basic needs like food and housing are getting scarce with each passing day so accessibility to this should be restricted and should be heavily monitored so that we don't cause more harm to the nature than good Happy Skye Happy Skye 1 year ago Could you post a list of supplements and other tablets you take daily? 6