Bacterial Communication via Quorum Sensing Bonnie Bassler (Princeton) Part 1 ,104,823 viewsMar 27, 2010

Bonnie Bassler (Princeton) Part 1: Bacterial Communication via Quorum Sensing 104,823 viewsMar 27, 201 iBiology 144K subscribers https://www.ibiology.org/microbiology... Bacteria, primitive single-celled organisms, communicate with chemical languages that allow them to synchronize their behavior and thereby act as enormous multi-cellular organisms. This process is called quorum sensing and it enables bacteria to successfully infect and cause disease in plants, animals, and humans. Investigations of the molecular mechanisms underlying quorum sensing are leading to the development of novel strategies to interfere with quorum sensing. These strategies form the basis of new therapies to be used as antibiotics. See more at http://www.ibioseminars.org 57 Comments rongmaw lin Add a comment... Stephen Goodall Stephen Goodall 6 years ago You are so interesting to listen to. Your emotions transfer directly into the information you are passing on. I can stay engaged listening to you even though I really may only get a small portion of it. Your ability to wrap up the large picture within the specifics is masterful and I'm thankful for you. Hugs :) 28 Abhijeet Singh Barath Abhijeet Singh Barath 7 years ago (edited) This was one of the best and most engrossing talk on a subject in microbiology that I have ever had. Thank u Dr. Bonie bassler:) I wish I have an opportunity to work under you someday. And I dearly wish they taught us microbiology like that in our medical school.. 19 Andrea Fabry Andrea Fabry 8 years ago Thank you for this information. I got goosebumps hearing about the squid's beneficial microbes. I study microbial nutrition - particularly natto - this encourages me in my efforts. Thank you again for your knowledge and passion. 4 Adams Nexus Adams Nexus 7 years ago Great vídeo! Very interesting to learn about communication of bactéria. Esta mulher é uma cientista admirável, muito bom este vídeo!!! 1 Ebrima Danso Ebrima Danso 9 years ago This is one of the best academic videos i have seen for now. Thank you and pleaswe stay healthy and strong so that you can give me more of this and to others. You are awesome 3 Aidan Karmali Aidan Karmali 6 months ago I am a physics major starting to work my ways towards applications in biology, and I must say that the excitement displayed in this video with regards to the process of discovery and to the various dimensions of interconnectedness being uncovered in (micro)biology is incredibly inspiring. Thank you for this wonderful video and for showing how passion can override the occasionally tedious and intimidating nature of exploring topics like these in great detail. 😁👍 Fates_Design Fates_Design 9 years ago Great videos and explanations, thank you :) pacmaneex pacmaneex 10 years ago in terms of time, how long did it take you to perform all of these experiments and reach those conclusions? i'm assuming you had many misleads, or am i wrong? p.s. great video, thanks! Christian Duerig Christian Duerig 4 years ago I am very fascinated by your talk and I wish you a lot of new results in molecular biochemistry. I will follow your research ! Helen Tran Helen Tran 1 year ago Thank you for such an inspirational talk! Amie Dinakanna Amie Dinakanna 8 years ago Just look at how passionate Dr Bassler is about her work. If only we could all be like that about what we do. Dr Bassler, I am in awe of your obvious love and excitement for and about your field of study. You are as beautiful as you are brilliant, and also, your sense of humour peeked through your presentation. Wow what a complete woman! Kudos to you. 2 Hockeygod98 Hockeygod98 8 years ago This is fantastic! Thanks for these. Leopoldo Mendívil López #SecretoAzteca Leopoldo Mendívil López #SecretoAzteca 1 year ago Wonderful, amazing!! Bonnie Brasser you are the Christopher Colombus of a new world of biological communiction - i wonder... what would you discover if you got into motor molecules - how they communicate - another great mystery... gem Barry gem Barry 5 years ago So so amazing, excellent. Clear great tone, nice illustrations. Good presentation 1 Muuip Muuip 3 years ago Excellent presentation! Great delivery! Quorum Sensing is very promising. 1 Dr. Vandana Gupta Dr. Vandana Gupta 5 years ago Very Informative and impresssive video. Thank You Dr Bonnie Baseler 1 joefromravenna joefromravenna 6 years ago I saw an article on the effectiveness of using certain naturally occurring clays as antibiotics; especially red . Makes me think that perhaps it is the clays that may be binding with the various inter and intra species communication molecules. http://www.nature.com/articles/srep19043 Roy Niles Roy Niles 5 years ago One of our most brilliant scientists. 2 Abdulaziz Shafi Abdulaziz Shafi 7 years ago its really interesting topic, brief explanation, I am doing seminar on it and it help me a lot Melissa Buchter Melissa Buchter 1 month ago My professor linked this to a PowerPoint book and at first I was like NOOOOO but you make it so interesting I ended up watching the whole thing and was left curiosity!!! Thank you!! MrFilu13 MrFilu13 1 year ago thank you mam, its very informative talk Nirmani Wicks Nirmani Wicks 7 years ago So clear and articulate Yut Verg Yut Verg 8 years ago Is it possible that bacteria ( viruses etc) could manipulate the system they colonize in order to make it behave in a way they are interested in? 1 Prashantee Singh Prashantee Singh 7 years ago Excellent talk...my concentration hardly shifted! Sienna Morris Sienna Morris 4 years ago You are a wonderful rarity, Bonnie Bassler. So often the fascinating world of microbiology (or just about any other field of science) is made dull or inaccessible by people who don't themselves know how to communicate. I loved this video. I look forward to watching more lectures by you. This presentation was wildly engaging and easy to follow while providing enduring interest in the subject. Thanks!!! 1 MrFilu13 MrFilu13 8 years ago thank you very much this is very impressive Clemens Van Stekelenburg Clemens Van Stekelenburg 6 years ago Bonnie Bassler is wonderful! I recently watched a lecture series by Yale's Stephen C. Stearns, but he is such an extremely unpleasant person, I could not finish the series. Bonnie Bassler, however, is a joy to watch and listen to, so I am sure I will do that a lot. Am already a fan. Princeton wins. 2 Qillz Qillz 10 years ago This is fascinating! Unfortunately, the vid stopped part way through, so forgive me if you already answered this, but could the manipulation of the peptides in these quorum sensing systems be an answer to the problem of evolved resistance to antibiotics? aamericuslakota aamericuslakota 9 years ago This is mindblowing. 1 wjestick wjestick 8 years ago Great information but I suspect that commercial interests will misdirect this line of research. The next logical question would be, how does our immune system interact with quorum sensing to protect itself from pathogens. And how can we enhance that. But the pressure will be directed toward, a patentable drug. Then natural solutions will be marginalised or outright banned. Marijuana and THC and Cannabidiol for example. Linux Graphix Linux Graphix 6 years ago bravo....beautiful discovery! 1 Dogma233 Dogma233 9 months ago English is so hard,but teacher is so interesting and excellent(my brain is booming) William Kimaru William Kimaru 5 years ago Excellent presentation..... Naimul Haq Naimul Haq 3 years ago The whole universe is quantum mechanical in nature, as long as we do not understand how quantum computation does many operations simultaneously and how superimposed states represents the various dimensions we live in, we shall know nothing. Yuanzhang Zheng Yuanzhang Zheng 8 years ago Thank you very much. Jerry Gundecker Jerry Gundecker 4 years ago "All the things we'd like to do," eh, Bonnie? I like that. Yut Verg Yut Verg 8 years ago It's quite astounding. But what is the interest of bacteria in colonizing big systems if these systems die ? Do they have an interest in their death as lions that kill their prey in order to eat them ? Would the bacteria survive the decomposition process ? 1 Vance D. High Vance D. High 5 years ago great talk Woof Bark Woof Bark 9 months ago P.aeruginosa sounds like the original gangster bacteria. Out of curiosity can these bacterium be tricked into not forming Biofilm in a lung through introducing some other less harmful bacterium? Probably a stupid question but I'm curious if this could be done. Marc Herrera Marc Herrera 7 years ago So they communicate like plants. They use a dispersal method since they are limited in sensing their surrounding environment. zyxzevn zyxzevn 2 years ago Enjoyed this talk about communication by bacteria side product. Funny thought: It seems the bacterial variant to piss, by which it can smell others. Just like dogs ;) Idea: Maybe we can confuse salmonella with boron? Glendy Patricio Glendy Patricio 3 years ago Someone please tell me what they feed on!!! MegxMeg MegxMeg 7 years ago is B. Bassler Dutch from origin? The Passionly Passionate Nightman The Passionly Passionate Nightman 9 years ago I saw this woman on ted Quorum sensing: Bacteria talks | Bonnie Bassler 61,976 viewsFeb 13, 2017 TED Archive 271K subscribers Quorum sensing is how bacteria communicates and decides the behaviors it will express . In this talk, molecular biologist Bonnie Bassler discusses the use of inhibitors that disrupt this to create a new type of antibiotic. Could this change the way we treat bacteria? TEDArchive presents previously unpublished talks from TED conferences. Enjoy this unedited talk by Bonnie Bassler . Filmed at TED2014. NOTE: Comments are disabled on this video. We made this difficult decision for the TED Archive because we believe that a well-moderated conversation allows for better commentary from more people and more viewpoints. Studies show that aggressive and hateful comments silence other commenters and drive them away; unfortunately, YouTube's comment moderation tools are simply not up to the task of allowing us to monitor comments on so many videos at once. (We'd love to see this change, YouTube.) So for now, if you'd like to comment on this talk, please use Facebook, Twitter or G+ to discuss with your networks.