STEVE HORVATH:DNA methylation studies of aging in different mammals" MARÍA BLASCO

STEVE HORVATH & MARÍA BLASCO (ORIGINAL) 183 viewsStreamed live on May 12, 2022 5 DISLIKE SHARE DOWNLOAD CLIP SAVE CENIE 499 subscribers STEVE HORVATH UCLA, DAVID GEFFEN SCHOOL OF MEDICINE se activation for the treatment of telomere loss disorders". 4 Comments rongmaw lin Add a comment... Julia Molina Julia Molina 2 months ago por favor podrian traducir! !! Gerardo Fabre Gerardo Fabre 2 months ago no hubo traduccion Epigenetic Clocks Help to Find Anti-Aging Treatments | Steve Horvath | TEDxBerkeley 40,973 viewsMar 19, 2020 TEDx Talks 35.6M subscribers Steve Horvath is a professor of human genetics and biostatistics at the University of California, Los Angeles. Horvath had a lifelong interest in solving an important problem in aging research: how do we measure aging? In 2011 Horvath and his collaborators at UCLA described the first age estimation method (epigenetic clock) for saliva based on chemical modifications of the DNA molecule known as DNA methylation. Two years later Horvath published an age estimator that applies to all tissues and cells of the human body. This discovery, known as the Horvath epigenetic clock, was unexpected because cells differ greatly in terms of their epigenetic patterns. Recently, he has studied treatments that slow or even reverse aging in humans. He and his colleagues have demonstrated that the epigenetic clock predicts lifespan and is related to centenarian status, obesity, HIV infection, early menopause, progeria, and many other age related conditions. Steve Horvath is a professor of human genetics and biostatistics at the University of California, Los Angeles. Horvath had a lifelong interest in solving an important problem in aging research: how do we measure aging? In 2011 Horvath and his collaborators at UCLA described the first age estimation method (epigenetic clock) for saliva based on chemical modifications of the DNA molecule known as DNA methylation. Two years later Horvath published an age estimator that applies to all tissues and cells of the human body. This discovery, known as the Horvath epigenetic clock, was unexpected because cells differ greatly in terms of their epigenetic patterns. Recently, he has studied treatments that slow or even reverse aging in humans. He and his colleagues have demonstrated that the epigenetic clock predicts lifespan and is related to centenarian status, obesity, HIV infection, early menopause, progeria, and many other age related conditions. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www.ted.com/tedx Featured playlist 22 videos TEDxBerkeley - February 8, 2020 TEDx Talks 86 Comments rongmaw lin Add a comment... David David 2 years ago Steve is modest as ever but the universal pan tissue epigenetic clock ought to be called The Horvath Clock in his honour. Wouldn't surprise me if he wins a Nobel Prize some day. 35 Anthony C Anthony C 2 years ago It’s crazy how many people dismissed this guy back when this speech was given...now that his group had amazing results everyone is trying to get on board😆 38 Jeff Miller Jeff Miller 2 years ago Interesting research. Would be fascinating to see a twin study of methylation. The fact that we can slow aging with behavioral change is hopeful. Even if it means my wife is right about the veggies. 6 tiberio135 tiberio135 1 year ago Excellent presentation Dr. Horvath. I will educate myself in your work only out of curiosity...since my wife calls me and 'old fossil' .Thank you. 7 Mehdi Bouchene Mehdi Bouchene 2 years ago You are a genius. Thanks for sharing. 12 Deborah Behr Deborah Behr 9 months ago I love this guy. Lets have him speak more. DK DK 1 year ago This is a great discovery and Steve seems like an awesome guy. But I wonder if DNA methylation is accurate in anti-aging treatments? People have reversed their epigenetic age by taking molecules such as NMN, meaning that their DNA methylation levels have gone down, but does it actually mean that physically the same they were as before? In other words, if I am able to reverse my epigenetic age by 10 years, I should look and feel exactly as I was 10 years back. But from what I have seen, it doesn't exactly work like that. So I guess it's possible to trick your body into having lower DNA methylation levels without actually reversing the physical state of your body in entirety. 5 Tom (Edge of Thought Ideas) Tom (Edge of Thought Ideas) 2 years ago “Your mother was right. Eat your vegetables!” -Anti-Aging Science man 💪 31 Joe Solla Joe Solla 1 year ago "Longer living through chemistry" - think I'll trademark that phrase. 2 G T G T 1 year ago I want to live to 1000. 100 is way too short these days. Too much to learn and experience. 63 Curly Bill Curly Bill 2 years ago Is this the start of longevity escape velocity? Kurzweil was right if it is. 18 Scott K Scott K 4 months ago I still don't understand the point of epigenetic clocks. It'd be one thing if the were designed to predict at what age we are likely to die, but I really don't see the point of learning one's current "biological age." For instance, I'm 36. Let's say an epigenetic clock informs me that I'm biologically 39. So what? Am I going to live to 85 or 110? What does being "39" when I'm 36 actually tell me? Nothing useful as far as I can tell. At most it might imply that I'm 3 years behind the trajectory of the average person. So does that mean I'll die 3 years later than average? Of course not. So what does it mean? Anything? 1 Monica London Monica London 1 year ago Can this apply to dogs? I wish my dog could live longer than estimated! 5 J Andersen J Andersen 10 months ago Great talk Diyetisyen Ahmet Akbulut Diyetisyen Ahmet Akbulut 6 months ago Genius. The Cartoon Club The Cartoon Club 2 years ago The newest Nugenics discovery is the start of a revolution. I wonder if I’ll read this comment in 3020 lol 22 Shawn Outler Shawn Outler 5 months ago This was 2020 it’s now 2022 what’s the hold up with the anti aging technology please don’t make us wait 50 yrs for this technology all the money backing this should be already halfway done 1 Calet Evelen Calet Evelen 1 year ago Who says German's don't have a sense of humor? 19 Bitcoin Yoda Bitcoin Yoda 1 year ago German Tech. Very gut. 2 Pavel Baidurov Pavel Baidurov 1 year ago Respect from Russia 2 Ezike Daniel Chichetaram Ezike Daniel Chichetaram 11 months ago Death is not a blessing irrespective of the animal rakesh vora rakesh vora 1 year ago Sir i am from india. What is the way to meet you. ? joerg-peter born joerg-peter born 1 year ago I apologize, I apologized before Martin Martin 1 year ago "hang in there" azuur asmr azuur asmr 1 year ago Eat your colors! 2 Ahmed Y Ahmed Y 1 year ago thanks FOR GIVING EVERYTHING i DIDNT WANT YOU TUBE. EXTORT ME TO AVIOD ADS! I cant understand the guy in the add- Elya Elya 2 years ago As if life worth living 2 Eday Hashim Eday Hashim 8 months ago Billionaires will start removing all studies & breakthroughs in anti-aging lol Cole Butler Cole Butler 2 years ago