Saturday, January 13, 2024
AGE REVERSAL Through Replacing MITOCHONDRIA Japanese scientists have made a big discovery in finding a molecule ,HKDC1, the protein
AGE REVERSAL Through Replacing MITOCHONDRIA
Reverse Aging Revolution
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12,230 views Jan 8, 2024 #Quercetin #DavidSinclair #berberine
Professor Vinit Mahajan from Stanford University presents age reversal through mitochondrial transplantation in this video.
https://link.springer.com/article/10....
https://onlinelibrary.wiley.com/doi/f...
https://www.biorxiv.org/content/10.11...
https://www.mitrix.bio/
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• Translating Mitochondrial Transplanta...
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Japan's New Age Reversal Discovery Revolutionizes Longevity
The AI Report
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20,551 views Jan 3, 2024
#longevity #antiaging #biotechnology
Japanese scientists have made a big discovery in finding a molecule that heavily slows down the rate of aging in humans.
This could redefine the way we approach longevity.
At the heart of this discovery
lies the HKDC1 protein,
a guardian of cellular youthfulness.
Think of our cells as bustling cities,
with organelles like mitochondria and lysosomes serving as essential infrastructures.
Just as cities thrive when their infrastructure is well-maintained,
our cells flourish when these tiny components are in optimal condition.
However, when they falter, aging and disease can ensue.
Enter HKDC1, the protein that emerges as a superhero in this cellular narrative,
actively stepping up during cellular stress to protect these vital organelles.
-----
Every day is a day closer to the Technological Singularity.
Experience Robots learning to walk & think, humans flying to Mars and us finally merging with technology itself.
And as all of that happens, we at AI News cover the absolute cutting edge best technology inventions of Humanity.
-----
TIMESTAMPS:
00:00 The Simplest Anti Aging Treatment
01:10 How HKDC1 works
04:26 Why Japan needs Age Reversal Treatments
-----
#longevity #antiaging #biotechnology
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85 Comments
rongmaw lin
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@AINewsYT
Pinned by The AI Report
@AINewsYT
9 days ago
Which country do you think is ahead in terms of Longevity Science?
> Please don't forget to like the video, subscribe and turn on notifications to always be up to date and to enable more videos to be created in the future! 😀
10
The AI Report
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3 replies
@terrydunne100
@terrydunne100
9 days ago
Fascinating. It looks like enough people are working in the field of age reversal right now to actually make a difference in the short term. Bring it on.
39
Reply
9 replies
@MrKoffeeKup
@MrKoffeeKup
9 days ago (edited)
I would love to see how Japan utilizes these new technologies in the near future. While I think the USA still has some great advancements based on its size alone Japan has managed some amazing achievements for a much smaller nation.
9
Reply
1 reply
@DaveEtchells
@DaveEtchells
6 days ago (edited)
One cautionary note: HKDC1 is way over expressed in cancer cells. That might just contribute to their longevity, but OTOH, could HKDC1 end up causing cancer as well?
(BTW, reference links would be very helpful knowing your vids, for readers who want to dive deeper.)
Very interesting vid as always, thanks!
5
Reply
@realAIDOPE
@realAIDOPE
9 days ago
There's no question AI will provide findings into Health that will dramatically improve healthcare and longevity. Always #AIDOPE 🍪
15
Reply
1 reply
@thegiggler2
@thegiggler2
9 days ago
Wouldn't this be bigger news if true?
19
Reply
2 replies
@patrickzupanc1795
@patrickzupanc1795
7 days ago
Thank you for your great work 👍
2
Reply
@kathb1683
@kathb1683
6 days ago
I pray there’s a lot of research insuring that “bad” cells aren’t accelerated as well.
3
Reply
@squamish4244
@squamish4244
3 days ago
If only the video gave us more detail on how they actually discovered this.
Reply
@Human_01
@Human_01
5 days ago
Intelligence is a good thing. It is vital for the future. I am thankful to the humans who can, could, and did understand my insights and were able to bring it to fruition.
1
Reply
@darkhorseman8263
@darkhorseman8263
6 days ago
HKDC1 overexpression can contribute to liver cancer.
There are ways to stabilize the electron transport chain to safeguard against that, though.
2
Reply
@DayonBledsoe2000
@DayonBledsoe2000
9 days ago
Thank you Japan, you are beautiful people and highly intelligent! Idk why America can’t be like you.
1
Reply
1 reply
@edwhite2255
@edwhite2255
9 days ago
Where are the studies that prove this supplement works and actually extends lifespan and healthspan
5
Reply
1 reply
@Human_01
@Human_01
5 days ago
This was also inspired by the intel/insight from my notebook (the leak)... Increasing cells resistance to energy damage that exists at the quantum scale among molecular structures. What it atp energy release; damages cellular dna structures. Limiting the damage atp causes results in longevity and anti-aging (i can summarize the process of the top of my head, despite having not looked at the document for years).
1
Reply
@user-xb1lt6vh2f
@user-xb1lt6vh2f
9 days ago
That would be wonderfull, if not an exact pill but the combinational therapy, I'd love to use.
4
Reply
@henryjraymondiii961
@henryjraymondiii961
1 day ago
Compared to the other hexokinases, HKDC1 was dramatically overexpressed in cancer tissues, indicating that this isoform might play an important and different role in cancer growth.🤔☹☹😮
Reply
1 reply
@driddy1
@driddy1
7 days ago
In spite of our present struggles to overcome the outmoded economic system of the world, the future appears increasingly bright ✨✨✨
Reply
@hasana4361
@hasana4361
5 days ago
We need this already
Reply
@user-ns8ht6iu4p
@user-ns8ht6iu4p
9 days ago
Cant wait to live forever
9
Reply
@174paul
@174paul
9 days ago
Can you provide the names of the researchers, or cite a research study?
3
Reply
1 reply
@emergentform1188
@emergentform1188
7 hours ago
wow wild, and great production quality on this vid!
Reply
@arthurhill365
@arthurhill365
15 hours ago
The governments of the world will never let it be distributed. Image if all the retirees who are currently collecting retirement benefits, either from the government or private retirement funds, living an extra 20 or more years.
Reply
@Palpatine4Senate
@Palpatine4Senate
9 days ago
So is this just a random block of text produced by AI and read by an AI voice with free stock photos and videos and royalty free music? What truth is there to this at all? Where's the link to this information?
5
Reply
@squamish4244
@squamish4244
2 days ago
It would be great if this was something that finally paid off. We're all running out of time.
Reply
@josephcarbone5379
@josephcarbone5379
7 days ago
Well done
1
Reply
@user-kz5cw2gj3w
@user-kz5cw2gj3w
4 days ago (edited)
Hold up. Why is this so unquestioningly considered a positive? It is actually scarier than the worse AI scenario if you think about it critically. We need a multidisciplinary examination of the ramifications this would/will have on society now, not when it is a done deal and disrupting everything.
1
Reply
@tadmarshall2739
@tadmarshall2739
3 days ago
The total lack of detail presented in this video convinces me that it was written by ChatGPT. No names of creators, or companies involved, no interviews or quotes, no references...
Reply
@YochananTuckkermen-qx9to
@YochananTuckkermen-qx9to
6 days ago
How can I believe this when someone else is sharing another person's discovery??
1
Reply
@ariffahmed943
@ariffahmed943
7 days ago
I like the English and praise for japan, not much about AI and genetics
1
Reply
@dougtrvl888
@dougtrvl888
2 days ago
Fantastic 😊
Reply
@jedwards1792
@jedwards1792
6 hours ago
HKDC1 is the supposedly miraculous molecule.
Reply
@MacarthurLouissaint-rz7tl
@MacarthurLouissaint-rz7tl
8 days ago
Can you do a video on reversing birth defects or disabilities in the mothers womb so that child don't have to be born with a birth defect
1
Reply
1 reply
@MarcMallary
@MarcMallary
6 days ago
After the cov jabs I will always be suspicious of the medical industry.
1
Reply
@luckssj
@luckssj
7 days ago
How does this work with Nattokinase?
1
Reply
@pavelbel
@pavelbel
9 days ago
Is It possible to say even less with more words ?
6
Reply
@pubwvj
@pubwvj
1 day ago
Written by AI? A lot of words to say very little.
Reply
@hasana4361
@hasana4361
5 days ago
How long do you thnk that it will be avaible
Reply
@romolob
@romolob
9 days ago
This video could be riassume in 1 minute instead re use picture and scene used already in other videos. You just put some visual in 1000 of words for nothing.
Also there is not any confirmation in regard of this news..
Sorry 👎👎👎
5
Reply
@Montie-Adkins
@Montie-Adkins
5 days ago
Many vids like this can be followed by a Google search and sure enough there is some supplement for the topic. This has nothing it's so new.
Reply
@1vootman
@1vootman
8 days ago
Lots of words, very little science
3
Reply
@alexsolutricine
@alexsolutricine
14 hours ago
When you see Sinclair you can be sure that is a scam
1
Reply
@miaya3898
@miaya3898
4 days ago
The next 3 years...right 😂
Reply
@hevechvy
@hevechvy
9 days ago
Just wait until quantum ai takes over
Reply
@human_isomer
@human_isomer
2 days ago
nice vision, but if it doesn't help in preventing cancer, this may be a curse more than a blessing.
Reply
@Grandmaster-Kush
@Grandmaster-Kush
9 days ago
No not 20 more years of waging I beg you
4
Reply
@joshlocher71
@joshlocher71
9 days ago
i would rather take the pill
1
Reply
@hameddesign70
@hameddesign70
6 days ago
we can see the death of the stars
Reply
@xueya2188
@xueya2188
9 days ago
Zero_balance_bot in action again.
Reply
@ArtII2Long
@ArtII2Long
1 day ago
Hypefest.
Reply
@davidshoemaker246
@davidshoemaker246
3 days ago
All hype and hope but little substance. Will stay tuned but have seen this all before not expecting much.
Reply
@ezkappdo
@ezkappdo
6 days ago
Oh great - one minute of mentioning a finding without many details, followed by 7 minutes of wild bullshit conjecture...click bait nonsense
2
Reply
@richardyensen9700
@richardyensen9700
3 days ago
Vapid cheerleading with almost no content on the science of HKDC 1! Please improve your status as educators by providing some real research summaries and understandings of mechanisms.
1
Reply
@stevemiller2210
@stevemiller2210
6 days ago
BS
Reply
@JohnSmith-vx5mt
@JohnSmith-vx5mt
4 hours ago
You ramble on pointlessly
Reply
@thewizardTim999
@thewizardTim999
2 days ago
Worthless non-informational propaganda
Reply
@CarlosSack
@CarlosSack
4 days ago (edited)
HKDC 1 protein
HexoKinase Domain-Containing Protein 1 .
⚗️🧫🌡️🧪🧬💉
1
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#mitochondria #reverseaging #lifespan #epigenetic #reprogramming #RestoreVision #AgeReversal #mitochondria #brownfat #Fasting #longevity #SIRT1 #d3k2 #spermidine #berberine #reverseaging #supplement #oskgenes #slowaging #resveratrol #stayyoung #EGCG #VitaminB12 #MethylDonors #TMG #NadBooster #Exercise #NAD #BeingHungry #Mitochondria #ALA #Metformin #CoQ10 #Carnitine #Antioxidant #LookYounger #Resveratrol #Quercetin #Fisetin #senolytics #OliveOil #Sirtuin #HIIT #aging #Lifespan #NR #Metformin #Berberine #ReverseAging #Epigenetic #OleicAcid #NAD #Sirtuins #Fasting #Longevity #RestoreYouth #Reprogramming #DavidSinclair #Healthspan #Younger #antiaging #DrSinclair #NAD #longevity #Bioscience #Epigenome #prohealth #donotage #renuebyscience #nuchido
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Reverse Aging Revolution
68.7K subscribers
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7:36
FIRST HUMAN TRIAL Shows A Supplement RESTORES Our Youthful NAD Production & FIXES NAD Decline
by Reverse Aging Revolution
36 Comments
rongmaw lin
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@ReverseAgingRevolution
Pinned by Reverse Aging Revolution
@ReverseAgingRevolution
4 days ago
~*~ Discount Coupon Code: REVERSE
🌏ProHealth Longevity 15% OFF NMN Pro 500 mg https://prohealth.pxf.io/NMN500 Calcium AKG Longevity 500mg Caps https://prohealth.pxf.io/CaAKG
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4
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@gregmattson2238
@gregmattson2238
4 days ago
you know, being 55 really sort of sucks. I'm mentally sharp enough to be aware that this has the potential to revolutionize everything, but I also realize that I could benefit from this treatment RIGHT NOW - and feel like the 10 years or so that it will take to get it into the general public will make me personally miss the aging reversal train.
I hope I'm wrong, but I doubt it. For now, its supplements, exercise, sleep and sauna - and please guys, work your ass off in the lab.
15
Reply
2 replies
@__Wanderer
@__Wanderer
4 days ago
Amazing - sign me up! I have multiple sclerosis and would love something like this! I think mitochondria dysregulation are also thought to be a cause for MS...
11
Reply
2 replies
@laurakl724
@laurakl724
4 days ago
My grandson has Leigh's Disease which affects the mitochondria. It is a neurodegenerative disease. There is a non-profit foundation that has been working tirelessly in finding a treatment/cure for the last 10 years. They are so close to a cure! Sounds like they may want to reach out and possibly partner with them.
6
Reply
2 replies
@Izakokomarixyz
@Izakokomarixyz
4 days ago
Ever since the 2000’s when I would see Andy Milonakis on television not aging, thats was when I realized that aging is not something that is inevitable.
1
Reply
@ericg6453
@ericg6453
4 days ago
Elevated heart rate could be a shock response, the body sensing insufficient O2 and attempting to get blood and it's cargo of oxygen to vital organs. You see this in trauma resulting in significant blood loss.
1
Reply
@susanc.2482
@susanc.2482
4 days ago
👍👍improve muscle, neurodegeneration and fur regrowth.... proof of concept works, amazing! Just need to push a bit quicker! Many antiaging therapies are working on the way, excited to see which is available first!🙏🙏
2
Reply
@Healthforeveryhome
@Healthforeveryhome
2 days ago
Thank you very much for your valuable information ♥👍👍
Reply
@monnoo8221
@monnoo8221
3 days ago
fascinating... also he business model: provides benefits only for a couple of days.
I think this approach will lose against its main competitors like OSK based reprogramming
Reply
@rdavidmurphy1
@rdavidmurphy1
4 days ago
Nice presentation but it would be good if it was possible to read the charts instead of just seeing you stand on the stage with a small chart
2
Reply
@janineclemons746
@janineclemons746
2 days ago
There have been studies in mice of FMT between young mice and old mice. The old mice seem rejuvenated by the young mice's input so to speak. I wonder if there is a similar systemic effect. We inherit our mitochondria from our mother and similarly our biome seems to come primarily from our mother. Is there mitochondrial crossover between the biome and the system?
Reply
@____2080_____
@____2080_____
4 days ago
I know that these researchers are looking to go the medical route. However, I would love to figure out a natural version of this to avoid both government overreach, as well as pharmaceutical methodologies that only drug creation.
But, since drugs and other nutritional molecules, used the same pathway, I would be interested in looking at technology that was discussed in the presentation and supplementing that user with something that’s not able to be patented and is known from vitamin research to help our mitochondria in a biogenesis sort of way.
One of the things that is known with the vitamin version of this is that mitochondria come and then go. Maybe this nutritional foundation will allow the body to receive the new mitochondrial substrate, and also generated within the human body as well. That way, we don’t create a drug dependency that Jacks, the bodies, natural systems and forces patients to be dependent on it.
A lot of this reminds me of the lips, nutritional supplements, that in further review, experts, suggest humans not to use, as it takes away from the bodies own ability to manage these systems in the body
Drug research company as they jump through FDA hurdles could look into creating usefulness versus repeatable product, at least this person will be appreciative
Reply
1 reply
@bertimus7031
@bertimus7031
4 days ago
I would be interested in interspecies transplantation of mitochondria. I wonder if Usain Bolt could donate some mitochondria. My second thought is using mitochondira from a tasmnian devil.
3
Reply
1 reply
@zibtihaj3213
@zibtihaj3213
4 days ago
How far r we from this coming into mainstream ?
5
Reply
5 replies
@whatthefunction9140
@whatthefunction9140
4 days ago
Are mitochondria the powerhouses of the cell?
1
Reply
1 reply
@antoniobortoni
@antoniobortoni
4 days ago
Having no friends get you old the most? probiotics i love them, they help me release stress and make way better my digestion, that's being young, just good ferment food, put the poops of kids in old people makes them young jajajaja, its not blood. Being young is a factor of being well, functional so all that make us more functional and well make our lives longer, because stress make us old, It's not like probiotics fix DNA like resveratrol, more like just like omega 3 make us work better and that is really good for us... So there is substances that make us really healthy like probiotics, omega 3... substances that fix our ADN and make us young again, and we can take them all, or make a special probiotics that produce young restoration substances like resveratrol or a super probiotics that make you young again, easily, by adding the genes that activate the production of resveratrol in plants but in probiotics and other young substances being produced in the gut. wow.
1
Reply
@caroroca9010
@caroroca9010
4 days ago
💕💕💕
Reply
@gastropodahimsa
@gastropodahimsa
4 days ago
For a similarity, a battery is just wrong. That's a little off-putting right a the start. Even a little condescending.
2
Reply
@JackAtkins-xz5wi
@JackAtkins-xz5wi
3 days ago
I'm a Prophet King Christ Star above all male Heads of State who speak English.
Reply
@alexeygrom1834
@alexeygrom1834
4 days ago
what a pity !! just a few days of youth
1
2024 - 4 MOST Promising Longevity Molecules You NEED To KNOW
Reverse Aging Revolution
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22,138 views Dec 23, 2023 #quercetin #Berberine #TMG
Dr. Brian Kennedy presents 4 molecules which show promising effects in both healthspan & lifespan in this video.
https://pubmed.ncbi.nlm.nih.gov/37289...
https://pubmed.ncbi.nlm.nih.gov/29631...
https://pubmed.ncbi.nlm.nih.gov/37637...
https://pubmed.ncbi.nlm.nih.gov/37925...
https://pubmed.ncbi.nlm.nih.gov/35584...
https://pubmed.ncbi.nlm.nih.gov/35050...
https://pubmed.ncbi.nlm.nih.gov/28199...
https://pubmed.ncbi.nlm.nih.gov/37904...
https://pubmed.ncbi.nlm.nih.gov/37697...
https://pubmed.ncbi.nlm.nih.gov/37217...
https://pubmed.ncbi.nlm.nih.gov/34952...
https://pubmed.ncbi.nlm.nih.gov/34847...
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Reverse Aging Revolution
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7:09
TAURINE Extends Lifespan & Healthspan
by Reverse Aging Revolution
66 Comments
rongmaw lin
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@ReverseAgingRevolution
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2 weeks ago (edited)
Life Extension, Taurine 1,000 mg https://iherb.co/PLGfk9mA
~*~ Discount Coupon Code: REVERSE
🌏ProHealth Longevity 15% OFF NMN Pro 500 mg https://prohealth.pxf.io/NMN500 Calcium AKG Longevity 500mg Caps https://prohealth.pxf.io/CaAKG
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6
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@Mark-sg2rg
@Mark-sg2rg
2 weeks ago
Among these 4, I think taurine is the most promising, affects all hallmarks of aging and affordable. Plus Dr Sinclair started taking it after the taurine's study published.
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18 replies
@rainerlanglotz3134
@rainerlanglotz3134
2 weeks ago
Gemifibrozil has a bunch of nasty side effects (Check wikipedia). I think we have to be patient here until better analogs are developped using the Gemifibrozil formula as a lead. The other 3 are all great and well tolerated.
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@richardgabbrielli3328
@richardgabbrielli3328
2 weeks ago
So taurine improves longevity but so do drugs that reduce amino acid uptake? Personally i think the overemphasis on mTOR in rodent models is missing the mark for human longevity and healthspan. Muscle mass/strength and cardiovascular fitness are some of the largest modifiable factors in longevity/mortality, why would I want to increase my frailty with low amino acid diet and fasting (which has also been shown to be less beneficial than exercise for autophagy)...?
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1 reply
@mag4926
@mag4926
12 days ago
If I'm not mistaken, Nestlé has claimed urolithin a as its own so it is currently not available for purchase anywhere. Is that correct?
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@hedu5303
@hedu5303
2 weeks ago
The real heros of our society
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@hedu5303
@hedu5303
2 weeks ago
The real hero of our society
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@carma23
@carma23
2 weeks ago (edited)
Knowing that Nestle (w/ Amazenthis) owns the rights of Urolithin A, makes me not trust these studies on this specific compound
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5 replies
@jordanong5114
@jordanong5114
10 days ago
Good thing anti aging happens at every year!
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@michael-qp9xd
@michael-qp9xd
2 weeks ago (edited)
Was excited about Urolithin initially but then looked more and more at each of newer studies over past years and results show in humans not much of any real benefit. Speaker here related to company so is very biased and overhyping. Developers could submit for ITP group to test urolithin A over past several yrs but appears not as probably be a big disappointment with no benefit to lifespan just as other studies showing no benefit to general health. A few compounds in ITP showing some benefits and these need to be studied more in humans.
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1 reply
@isa-manuelaalbrecht2951
@isa-manuelaalbrecht2951
2 weeks ago (edited)
I observed a mix if dif aminos , but tested onto the patients will work...but then add OM units incl.med.mushrooms like cordyceps militaris and others...🎉🤩😏
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@TheAnzack
@TheAnzack
2 weeks ago
why does taurine make me so unwell if its so good for me? makes me super angry- although i do have sibo so maybe some neurotransmitter deficiencies?
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3 replies
@cactuscanine3531
@cactuscanine3531
2 weeks ago
Have any of these substances been through ITP?
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@wollahwollah1060
@wollahwollah1060
2 weeks ago
There should be a summary description of the video or even in the comment as always
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@Ardentic-aa
@Ardentic-aa
2 weeks ago
There's no such thing as mtor. There are two complexes and they act independently. People need to stop confusing and conflating things.
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@elliottrubenstein1746
@elliottrubenstein1746
2 weeks ago
Very interesting.
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@thesuperbiketour2251
@thesuperbiketour2251
2 weeks ago
Extra Virgin Olive Oil too
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1 reply
@DayonBledsoe2000
@DayonBledsoe2000
4 days ago
Fasting dose not help cure Ageing it helps with diet!
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@radovan739
@radovan739
2 weeks ago
Used Taurine for while,did not notice any change?
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6 replies
@Hasanafandi-qj6oh
@Hasanafandi-qj6oh
2 weeks ago
Untrue, only eat less live long.
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@holt7088
@holt7088
2 weeks ago
What are the 4?
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4 replies
@tomu4725
@tomu4725
2 weeks ago
Comment for the algorithm 👍🏻
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1 reply
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