3 Things Causing INFLAMMATION Mark Hyman

3 Things Causing INFLAMMATION In Your Body & How To PREVENT IT | Mark Hyman 607K views 2 years ago Mark Hyman, MD If you have a chronic illness, you've got inflammation. Inflammation is often hidden or silent, something that we can't see or feel, ... 24 auto-generated moments in this video Transcript 0:00 if you have high cholesterol and no inflammation they're very low risk for heart disease but if you have 0:05 high cholesterol and high inflammation those are the people who are at risk for heart disease 0:14 what are the top three things that people are doing the root factors that are contributing to the chronic 0:20 inflammation epidemic that we're facing today i'm gonna get to those things but first 0:26 i don't know if people actually know what inflammation is let's go into it so people know that if you have a sore 0:32 throat it's red painful swollen 0:38 and and um that's inflammation and it hurts right the the ancient 0:44 description of inflammation was rubor collar dolor and tumor so tumor is swelling rhubarb is redness 0:51 dolores pain and color is heat right 0:56 so we have to understand that those are the those are the cardinal 1:02 features of inflammation but then you go well i don't really feel inflamed my throat doesn't hurt my 1:08 joints aren't swollen i don't have a rash what do you mean by inflammation it's 1:13 it's what we call hidden or silent inflammation and that is the problem it's the 1:19 inflammation that we don't see that we can't feel that's causing all the chronic diseases that we see today 1:26 heart disease cancer diabetes alzheimer's depression not to mention obviously autoimmune disease allergies 1:32 and so forth those we know there's inflammation in those but i mean do people think of being overweight is an inflammatory state do people think of 1:38 diabetes as an inflammatory state if you don't think of depression as an inflammatory state no but inflammation 1:44 is causing all of those chronic diseases so back to your question what are the 1:49 biggest drivers of inflammation well it's something that has been only recently 1:56 a phenomenon in traditional medicine and has been ignored pretty much forever except by functional medicine which is 2:03 your gut your microbiome turns out that 60 to 70 percent of your immune system is in your gut 2:10 why is it there well it's the place where you're exposed to all the foreign materials every day 2:15 more than anywhere else the purpose of your immune system is to identify friend from foe and to get rid of the bad stuff 2:22 so when you're eating pounds of a foreign material namely food and you have three pounds of form material in 2:29 there namely bacteria that's a lot to handle so the ability of the gut to sense what it 2:36 should take in to keep out the things that shouldn't be in there is so important and so having a healthy 2:42 microbiome allows us to properly regulate our immune systems 2:47 and to let in the nutrients that we need proteins the amino acids the fatty acids 2:52 the sugars and carbohydrates that we need the nutrients we need but it keeps out all the bad stuff it's the first 2:58 line of defense first line of defense so when that barrier gets broken in the gut all of a sudden your immune system is 3:04 exposed to a sea or actually more accurately exposed to a sewer 3:11 and and so that starts to piss off your immune system and you start to create systemic 3:16 inflammation so the microbiome is is really important and we're just beginning to understand how to identify 3:21 what's out of balance in there and how to correct the system traditional medicine is still very much behind the 3:27 eight ball in this functional medicine is way ahead by 30 40 years on understanding one how to identify 3:33 dysfunction in the gut how to repair a leaky gut how to reduce inflammation how to restore a normal microbiome now 3:39 before we go to the other two just to jump in the ancients knew a little bit about this yeah talk about that uh 3:46 there's a famous ayurveda quote uh that really says if your gut's not healthy 3:51 you're not healthy and if you want to fix disease focus on the gut so this has been known for a long time 3:57 uh actually this idea wasn't new eli metchnikoff at the turn of the 1900s was a scientist 4:03 who first came up with the notion of the gut as a source of chronic illness 4:09 they had some wacky ideas about how to deal with it which was take out your colon which i would recommend 4:15 but they were on the right track which is problems in the microbiome in the gut cause systemic disease 4:22 and the solution is not cutting out your colon it's mixing the gut but but it was it's not something 4:28 that knew and hippocrates says you know health doesn't health and disease starts in the gut absolutely 4:35 that was the first one that you wanted to go into what are two other ones that you want to mention and there's a lot of 4:41 them that are out there but we're talking about the top three what are two other ones you want to make the other big source of inflammation is our diet 4:47 and not any um random thing from our diet but the amount of starch and sugar in our diet 4:53 that drives a dysfunction in our metabolism called insulin resistance it's essentially like 5:00 uh where we become resistant to the effects of insulin and our bodies need to make more and more insulin to 5:07 regulate our blood sugar and that is because we're flooding our system with pharmacologic doses of starch and sugar 5:12 about a pound a day per person which is just historically unprecedented and that insulin resistance 5:19 causes the development of specific kinds of fat cells they're called adipocytes 5:26 there are specific kind of fat cells in the gut around your belly your belly fat that produce a class of compounds called 5:32 adipocytokines cytokines you might have heard about with covate or the cytokine storm 5:38 these are the messenger molecules of your immune system and when you have a lot of these belly 5:44 fat cells made from eating starch and sugar caused by too much insulin and insulin 5:49 resistance it creates systemic inflammation so it literally puts your body on fire 5:54 so if you're overweight if you have diabetes if you have high blood pressure if you have heart disease 6:00 if you have dementia these are all related to this phenomena of too much starch and sugar and the systemic inflammation 6:06 we now know that for example if you have high cholesterol and no inflammation there are very little risk for heart 6:11 disease but if you have high cholesterol and high inflammation those are the people who are at risk for 6:17 heart disease so when you start to look at inflammation in the body it's not what we can feel but there are ways of 6:24 measuring through laboratory testing the amount of inflammation in our body and we're going 6:29 to become more and more sophisticated about this david furman at 6:34 stanford who's a scientist and doctor developed through technologies only 6:39 recently available big data analytics giant throughput analyses where you can look at thousands and thousands of blood 6:45 markers i mean we go to the doctor we get 10 20 lab tests right 30 40 maybe 6:50 50. there's thousands of molecules floating around your blood and most of them we completely ignore so he was like 6:57 i don't care what we're actually measuring let's look at what actually matters and so he put thousands of these 7:02 chemicals through analytic machines correlated with people's clinical history and was able to find four biomarkers of inflammation and immune 7:09 dysregulation that are highly predictive of aging highly predictive of heart disease cancer diabetes alzheimer's all 7:15 those diseases so we are going to become more and more sophisticated at our ability to look at inflammation people 7:21 want to know more about it they can go to edifice i think it's edifice health is the company which is uh actually 7:27 commercializing this test but but there's other tests we do like c-reactive protein to help to look at inflammation but insulin resistance is a 7:34 big driver of inflammation because it makes your belly on fire literally and 7:39 these fat cells are just pumping out tons of inflammation throughout your body 7:45 the third thing that is really important to understand is that stress is inflammatory chronic stress causes 7:51 inflammation in the body through a number of different mechanisms that one stress makes you insulin resistant so 7:56 it'll contribute to just making you overweight and belly fat even i mean i had a patient once where i this was so 8:03 clear she had a daughter who was in israel it was during the time of sort of uh the 8:09 infata the uprising a few maybe a few decades ago and she was terrified every 8:14 day that her daughter was going to get killed in some kind of bomb or some kind of attack during this palestinian 8:20 uprising and so she couldn't she couldn't sleep she was she wasn't even overeating but she just gained all this 8:25 weight and as soon as her daughter came back from israel she lost 40 pounds 8:31 just like that without changing anything so sometimes stress can be a very big factor in instant resistance it also um 8:37 affects your your inflammatory response and creates an increased inflammatory response so if 8:43 and this is interesting if you look at the data on what we call sociogenomics which is the ways in which our social 8:49 interactions cause changes in gene expression you can be having a conversation with someone 8:55 and if they're in conflict with you if you're oppositional if you're having an emotionally charged negative 9:02 interaction it will turn on genes of inflammation if you have a loving connected 9:08 conversation with someone it will turn on genes that shut off inflammation 9:13 so your mind your meal your your brain is the most potent 9:18 pharmacy ever and it will drive either inflammation or it will stop inflammation simply by your thoughts so 9:26 you have to kind of look at that and and and that's something we haven't talked about a lot is how do we master our minds most of us are victims of our 9:32 minds activity and we train our muscles we train our body we increase our metabolism nobody knows how to train 9:38 their brain to actually function better from the perspective of being in control of your thoughts and that is that's not an easy 9:45 one it's a whole other topic for a podcast how big of a challenge is the topic of 9:51 inflammation like really like put it in a sense of a scale in terms of all the things the 9:58 world is dealing with when it comes to problems with health how directly tied in is inflammation with those problems 10:05 uh it's probably the number one driver of all the misery we see in the world uh 10:12 there's a beautiful new book that was written by raj patel and rupa maria 10:18 who i've had on the doctor's pharmacy podcast called inflamed and it's about the 10:23 the biological the social economic and political consequences of 10:30 an environment and a diet that's driven systemic inflammation throughout society 10:35 and it's staggering when you start to look at it you know oppression is inflammatory and there's so many people oppressed and struggling 10:42 in this society the diet's inflammatory the social structures we have inflammatory and so 10:48 inflammation when you look at all the problems that are facing humans um in terms of health 10:54 uh it's and even in terms of um some of the socio-economic issues that 11:00 inflammation is such a big driver and understanding how we calm that down is so so important uh one of the things 11:07 that it does which i think is something people don't understand when you look at our society we see 11:12 so much conflict so much divisiveness so much hatred so much intolerance 11:18 i don't remember it like this growing up i mean i just don't i mean the the diet wars are terrible the 11:25 republicans democrats are no longer working together in any meaningful way 11:30 um you know we've got religious conflict political conflict 11:36 we've got the divisiveness in this country where we had sort of a takeover of the capital 11:42 by a whole bunch of people who were you know hopefully making the world a better place but really that was not a very helpful act 11:49 so why is it happening well it turns out that uh your brain when it's inflamed 11:55 doesn't work and all the things that we see as behavioral disorders 12:02 as violence as depression anxiety 12:07 mood disorders the opioid crisis turns out that a lot of these things are driven by inflammation in the brain 12:14 and and what's happening often is that the inflammatory processed diet that we have the changes in our microbiome 12:20 because of our diet because of c-sections antibiotics and toxins and all the things that damage our gut microbiome because of glyphosate 12:28 all that leads to inflammation and when you have inflammation like that in the body it disconnects 12:34 the ancient limbic brain the reptile brain the fight-or-flight response from the frontal lobe which is basically the 12:40 adult in the room your executive function your higher self so when your higher self and your lower 12:46 self are not talking to each other when your survival brain and your sort of mature 12:52 grown-up brain that makes sure you don't do or say or act in ways that are damaging or harmful to other people 12:59 that connection gets weakened or it breaks and so when you look at for example 13:05 diet studies in prisons or in juvenile detention centers it's so impressive because simply swapping out healthy food 13:13 an anti-inflammatory diet for an inflammatory diet in prisons cuts a violent crime by 56 percent they had a 13:20 multivitamin by 80 percent in juvenile detention centers these kids are violent 13:25 91 reduction in violent behavior 75 reduction administrates 100 reduction 13:31 suicide rates in this group which is the third leading cause of death in in adolescent males 13:37 and you reduce it by a hundred percent simply by changing the diet why does it work it works because it 13:44 cools off the inflammation in the brain is causing a disconnect between people's 13:50 ability to have executive function to have the grown-up in the room to have 13:55 the higher self show up and say gee maybe i shouldn't punch this person or maybe i shouldn't cut them or maybe i 14:01 shouldn't shoot them or you know maybe i shouldn't be in this violent oppositional 14:06 life and i think i don't know how much has contributed to the divisiveness in our society 14:12 from the food but i i think it's way more than we think and and we've had david promatter and his son 14:19 austin on the podcast talking about their book it which describes this phenomena and 14:24 the science and the neurology behind the way our diet affects our brain and disconnects our our limbic brain from 14:31 our frontal lobe driving violent and disruptive and divisive behavior 14:36 well one of the unique things that's happening in today's world that is built on top of all the different 14:41 things you're talking about is that there are a lot of people getting rich off of creating this inflammation we 14:47 have the food companies that are getting rich by marketing and selling high sugary foods 14:55 to the public we have the news media that's literally making incredible 15:00 millions of dollars hundreds of millions of dollars by driving inflammatory style news which drives inflammation in people 15:07 creates more stress and the advertising is all about inflammatory products right all about inflammatory products 15:14 food and many other factors that are out there too so a unique thing that's going on in the 15:20 world today that's important to highlight that has really never been there at this 15:26 level is that through really the hijacking of media 15:31 and the use of media to grow these large companies we now are able to spread 15:37 inflammation so rampant and there's a very few and small group of individuals that are getting 15:44 dramatically wealthy off the process yes you know i think you know a lot of stuff started off with good intentions that 15:50 had bad consequences right in the uh post-world war ii era we 15:56 needed to scale up agriculture to feed a hungry world a growing population to 16:01 produce a lot of cheap carbohydrate starchy calories and we did a great job we did a great job the average american 16:07 has 500 more calories than they did in 1970 available to them to eat and they're eating it which is why we're all 16:12 so unhealthy that was a good idea but the unintended consequences have been devastating not 16:19 only to human health in terms of diabetes and obesity i mean when i was born there was a five percent obesity 16:24 rate now it's 40. it's an eightfold increase in obesity in my lifetime 16:31 uh but we've also created unintended consequences for the environment and and 16:36 climate and the changes in our in our biodiversity and loss of species and the 16:42 damage the soil and our water systems because of how we're growing food so we've created all these unintended consequences in the same way 16:49 you know these it's food companies we're not actually designing foods to drive all these 16:54 problems but we're locked in a system where the status quo is trying to be preserved so they can maintain their 17:00 market share their profitability and they're trying to navigate and figure out how to shift because culture's 17:05 shifting demand is shifting but you know we we have a tremendous amount of money that goes 17:11 into preserving the status quo how we grow food what we grow the processed food industry the marketing the food i 17:16 mean we spend billions of dollars um from the food industry get spent billions of dollars marketing and 17:22 advertising bad foods and the worst the food the more money they spend advertising uh and 17:28 and what's worse is it's it's hidden advertising now that's really a problem and so these algorithms on the on these 17:34 um social media drive you into more and more of the same so if 17:40 you click on a conspiracy one conspiracy theory you're going to get fed 10 other conspiracy theories so i met these 17:46 people that believe in all these weird seemingly disconnected conspiracy theories because that's that's the universe they live in so we live in 17:51 these self-reinforcing information bubbles that are driven by algorithms and the algorithms where they're 17:56 designed to give people stuff they like to show them if they want a nice pair of shorts or a bathing suit that they might 18:02 like again well-intentioned well intentioned but the consequences now we sort of let the genie out and uh it's 18:09 out of control and so even the people who develop these systems i mean i don't think mark zuckerberg is evil or had an 18:16 evil intent to create more divisiveness and conflict and disruption in the world and violence no i don't think so but i 18:22 also think that the incentives now are to keep doing it and not to stop so we have to start to 18:29 look at what we're doing and create different forms of 18:34 communications and media and social media that are not driven off of these 18:39 algorithms that tend to cause more disruption more divisiveness and and and are incentivizing the wrong 18:46 thing i mean one of the things that's just shocking to me is forget all the ads on tv that kids see and there's about 10 billion dollars spent on all 18:51 that there's there's 500 billion 18:57 ads 500 billion ads in one year directed at children for junk food on facebook 19:05 that's terrifying to me because the parents don't even know it nobody it's like you can say oh don't watch your tv 19:10 kids or don't watch those commercials about you know fruit loops but it's all the hidden 19:15 stuff it's all it's all and it's all stealth it's embedded in games there's free games for these kids on social 19:20 media and they they play these games but in the games they highlight mcdonald's or they highlight coca-cola they have 19:25 these different kind of food companies that are paying for it and it's it's really co-opting these kids 19:31 brains it's copying their their uh their their own free will in a way and i think 19:37 that's what scares me more than anything is is the usurping if we will by this digital persuasion economy that's using 19:43 algorithms to target us in ways that we that it seems to be things that we like but it actually keeps it spirals out of 19:49 control and so we have to get we have to get a way to to solve that whether it's 19:54 inventing uh parallel platforms that people can use where that's not happening in social media platforms or 20:00 whether it's it's regulation or legislation this is this has gotten to be quite dangerous it's multi-faceted 20:07 but most importantly we have to have a dialogue about it and even more important than that is that you the 20:12 person that's watching the person that's listening today you have to be the ceo of your health you have to be the ceo of 20:18 your family's health because ultimately you know regulation can do a lot but it can only do so much we at the end of the 20:25 day have to drive education for ourselves and for our family and that's what this podcast and your work is all 20:30 about so let's continue down the topic of inflammation patient comes to you today right what 20:36 are the signs and what are the ways that the patient says ouch that are an indication to you 20:43 that they have rampant chronic inflammation that is taken over and 20:48 hijacked their body it's not that hard 20:53 pretty much anybody with any chronic disease inflammation is a player um 20:59 and and and so whether you have the typical things that we understand is inflammation like autoimmunity or allergy 21:05 or eczema or skin disorders or whether it's the silent inflammation that's causing heart disease and cancer and 21:10 diabetes and obesity and alzheimer's anybody with a chronic condition is typically inflamed at some level 21:18 so my job is to then navigate and figure out what's causing it because when you get to the root of inflammation 21:25 you don't actually have to treat the diseases directly they don't really treat diabetes i don't treat alzheimer's i don't treat 21:32 heart disease i don't treat cancer i simply change the biology of the body to 21:39 normalize function to reduce inflammation and as a side effect these things go away 21:44 and i think that's a really important concept because if we don't understand that 21:49 um root cause medicine is the way we need to go forward then we're going to just be 21:56 constantly spinning out on all these new drug treatments and spending billions of dollars to address this i mean they 22:02 found oh alzheimer's is an inflammatory disease of the brain so what do you have to do well they did a whole study taking 22:09 advil it didn't work and it caused all these side effects why because they didn't get to the root of the inflammation uh recently a big study 22:15 came out on aspirin doctors have been saying take aspirin to reduce inflammation to prevent heart attacks 22:21 well i if you read my stuff over the years i've always said bad idea there are maybe some people who would 22:28 benefit but aspirin is not a side effect-free drug and kills as many people as asthma or 22:34 aids a year because of bleeding stomach bleeding gastrointestinal bleeding brain bleeding 22:39 strokes hemorrhage so the recent studies show that oh sorry guys we were wrong you can't just take 22:46 aspen to reduce inflammation and prevent heart attacks because it's going to kill you it's more likely to kill you than the heart attack so stop taking it which 22:53 was a huge shocker because if you talk to any cardiologist or talk to any primary care doctor 22:58 everybody was on board and i was kind of shocked because i looked at the actual science that was supporting this 23:04 and i even look at the american college of cardiology risk calculator there's actually a calculator 23:10 on the american college of cardiology website to put in whether or not you would either get harmed or have benefit 23:16 from aspirin and most the people who are on aspirin actually don't even qualify or didn't 23:22 qualify according to the previous guidelines now there's a whole bunch of people who who shouldn't even according to those guys let's be taking it so 23:29 i think that it's backwards to say we're going to shut off inflammation with anti-inflammatories or immune 23:34 suppressants i mean they're talking about using drugs like humera which is a 50 000 a year anti-inflammatory 23:41 drug that's used for autoimmune disease for depression why because 23:47 depression is inflammation in the brain the key isn't to shut up inflammation when the drug is to get rid of the source of inflammation 23:54 how does traditional and conventional medicine again well-intentioned how does traditional and conventional 23:59 medicine look at and treat chronic inflammation like how do they where do they think it comes from 24:05 and then how do they decide how to tackle it you know it's just shocking to me that there really isn't a conversation about why 24:12 oh we know alzheimer's is inflammatory oh we know depression is inflammatory we know heart disease inflammatory we know cancer is inflammatory 24:19 okay so we need to give you anti-inflammatory drugs there's no questioning of gee 24:25 why in the first place is your immune system so pissed off what's creating inflammation 24:31 and we know so much about it it's not hard it's it's our diet our inflammatory 24:36 diet it's stress it's our microbiome issues it's 24:42 triggers that for example might be from latent infections or allergens or toxins all these drive inflammation 24:48 so as a functional medicine doctor my expertise is in being an expert in understanding toxins 24:55 allergens microbes stress and diet because those are the things that drive inflammation and so every individual has 25:01 a different cocktail of things that are off but my job is to figure out what is their particulars triggers and get rid 25:07 of them and then help their body on the other hand calm inflammation down so there's a whole bunch of things that 25:12 cause inflammation but there's a lot you can do to reduce inflammation and it's not by taking advil or aspirin 25:19 or steroids or some chemo drug or a biologic that costs 50 25:24 grand a year it's by the simple things that we know how to do food is medicine anti-inflammatory 25:31 exercise is medicine anti-inflammatory sleep is anti-inflammatory meditation's anti-inflammatory yoga is 25:37 anti-inflammatory and then there's a whole bunch of supplements you can take to help reduce inflammation like omega-3 fats and vitamin d and probiotics and 25:45 zinc and and all the phytochemicals you can eat in your food that actually help reduce inflammation all the spices and 25:51 all colorful fruits and vegetables so there's so much you can do to raise inflammation in the ways that we see now 25:57 if you have uh some latent thing right if you have a lot of heavy metals or if you have 26:03 a terrible bug in your gut or bacterial overgrowth or you have some particular gluten sensitivity you're going to have 26:08 to deal with those things too but for most people the basics just work so well well let's talk about those basics you 26:14 talked about food and you talked about some of the foods that help and we'll chat a little bit more about that but 26:19 what are some of the examples of the foods that might hurt what are some of the foods that are out 26:25 there that could be driving or at least supporting the process of chronic inflammation and why 26:32 do they support that well it's both what we're eating what we're not eating right so we're eating too many inflammatory foods sixty percent of our 26:38 diet in america is ultra processed food and what is that talk about the stuff that you see on the shelf what is an example because you 26:45 know one thing i've realized and why i want to break this down is that if you go to times square you go here in santa monica where we're recording and you go 26:51 up to most people and you say hey do you eat healthy most people are going to say yeah i eat healthy because everybody has 26:56 a different definition of what it is or you ask somebody do you eat a lot of processed foods and most most people say no i don't need that much a little bit 27:02 here and there so describe it what are we talking about here in ultra processors there are a few commodity crops that are supported by all our 27:08 government supports from the farm bill that are the raw materials for processed food corn wheat and soy 27:16 and they're turned into all sorts of weird products uh the corn is turned 27:21 into all sorts of food additives and high fructose corn syrup the wheat is turned 27:27 into highly pulverized flour which is highly inflammatory the oils that come from soybeans and 27:34 corn are often highly processed and inflammatory so we're eating a lot of ingredients that 27:42 are derived from these commodity products in ultra-processed food that we're not even aware of so when you read 27:47 maltodextrin or something on a label you don't know where that came from that's a byproduct of corn from the from a 27:53 science project in the factory uh when you eat high fructose corn syrup same thing so we're eating ingredients that 27:59 are made from commodity crops they're basically the same three ingredients made into all sizes color shapes 28:06 of of chemically extruded food-like substances so if you actually cover over 28:13 the packaging and look at the ingredients you literally would see the same ingredients on almost every processed 28:20 food we know with a few little tweaks here and there and you can actually even tell what it is by reading the ingredient 28:26 list that's an ultra processed food if you buy a can of tomatoes and it says tomatoes water and salt you 28:33 know what that is if the ingredient list is you know 14 15 35 items um and half of them you 28:40 can't pronounce don't recognize they wouldn't have in your medicine cupboard or your kitchen cupboard then you should not eat 28:46 them right i mean why should we be eating butylene hydroxytoluene or 28:52 or orthodextrin or all kinds of weird compounds that 28:57 are not our natural food supply so those are ultra processed foods and it's a huge component of our diet and it's 29:03 highly inflammatory so that's 60 of calories on average and when you think of all the 29:10 people who don't eat that much processed food and people are eating it might eat 70 80 right when you average a lot over all 29:16 americans it's about 60 and kids it's even worse it's 70 percent 29:22 70 for kids i think 67 is something it's like terrifying to me so that is really 29:27 what we should be focused on not eating and it's driving inflammation and sugar and starch is number one two and three 29:34 all the food additives we eat about five pounds of food out of the year and they can be inflammatory for example all the 29:39 thickeners emulsifiers things like carrageenan and gums that are used in processed food 29:45 they often have something called microbial transflutaminase which is a gluten product that they use to hold the food together and all these emulsifiers 29:52 they cause leaky gut so these damage your gut and when you have a damaged gut then guess what the floodgates open 29:59 like we talked about earlier in the in the podcast you start getting food proteins and bacteria proteins leaking 30:05 into your bloodstream your immune system gets all pissed off and it creates this vicious cycle of inflammation so eliminating all that weird stuff is so 30:12 important if you read the label and you don't know actually everything that's on there and you can't pronounce it you 30:18 wouldn't have it in your medicine cabinet don't eat it let's talk about next another category 30:25 that is directly connected into inflammation and that is sleep and one 30:30 of the biggest drivers of sleep that is affecting so many people is sleep apnea 30:37 talk about sleep apnea and its direct connection to inflammation for most people and how can increase weight gain 30:43 and a whole list of other things that are there it reminds me this guy actually uh sleep apnea is basically where you where you 30:50 have multiple episodes of stopping breathing at night so you will snore 30:57 you might stop breathing for seconds or minutes your sleep's interrupted 31:02 and it's often not diagnosed because you're asleep and you don't know you're doing it uh your partner might yell at you or 31:08 scream at you or move to another room or put in your plugs uh but you can actually use devices one of them is a 31:15 great little app it's called sleep cycle and it just records your sleep on your phone and you don't need 31:21 anything it's just you put your phone by your bed and you can have it on airplane mode even and it records your breathing 31:27 and your sleep and your snoring and so you can see and hear your snoring from the app so i i know my stepfather was a 31:34 big snorer he never believed it he had severe sleep apnea and i literally recorded him with my 31:40 cassette recorder back in the 70s because he didn't believe me but you can hear him just snoring like a an elephant 31:45 you know so it's really common it's often associated with being overweight 31:50 with having a thick neck with um sometimes structural issues a narrow 31:57 palate various things with your teeth so you can be thin in habit but there may be airway issues uh there can be central 32:03 sleep apnea obstructive sleep apnea so it can come from your brain or from your your obstructive airway and what that 32:08 does have those repeated awakenings to the night and the decreased quality of sleep it it actually causes insulin 32:14 resistance it actually causes diabetes it actually makes you crave more sugar and eat more sugar and carbs and and you 32:21 can often fix weight issues or diabetes or obesity unless you fix sleep apnea and it reminds reminds me of 32:28 a patient i had when i was at canyon ranch who was a lawyer and he's like look i can't lose this weight i'm 50 pounds overweight can you help me i'm 32:34 like okay well talking about your life well i'm a lawyer i'm like okay start getting to me how do you sleep well 32:40 okay and i said well i'm tired all the time i said well it means oh yeah well i i have to have a stand-up desk this is 32:45 before stamp desks are possible or i mean we're popular like you know 25 years ago because if i don't if i don't 32:51 stand up i fall asleep at my desk i'm like okay well how about we check for sleep 32:56 apnea and he had terrible sleep apnea we gave him a treatment for it a cpap machine and he lost 50 pounds like that 33:03 and his insulin resistance went away simply by sleeping so sleep is so important in regulating your metabolism 33:09 and inflammation and you know we think of snoring as kind of like a funny thing and we might hit our partner or laugh at 33:16 our parents or grandparent but really as a dear friend of both of ours uh dr 33:21 steven lynn a dentist down in australia and he says snoring is choking so you have to think of snoring as 33:28 choking at night so if you know if you're snoring or anybody else is snoring you're choking and you're 33:33 choking and that prevents you from getting the right amount of air and another version of that that's milder is 33:38 breathing through your mouth you've done some episodes on this i've done some episodes on this if you're breathing through your mouth at night and not 33:44 through your nose which is how we're designed to that's also a sign that you might have a mild form of sleep apnea 33:50 that needs to be addressed because it's directly tied into promoting inflammation in the body let's talk 33:56 about another category of things that is a driver of inflammation and that's our 34:01 sedentary lifestyle talk to us more about that yeah i mean sitting is inflammatory as we sit here 34:07 and do our podcast and that's why um so much of us are are struggling is 34:13 because when we don't move uh we we are actually increasing 34:19 the the poor metabolic function that we have increasing the risk for muscle loss increasing the risk for insulin 34:24 resistance increasing risk for just chronic inflammation in our body so 34:30 being sedentary is a huge risk for inflammation on the other hand exercising enough but not too much right if you 34:36 over exercise if you're ultra marathoner or marathon runner it creates more oxidative stress and inflammation in the 34:41 body but if you do regular exercise you literally can reduce the inflammation in your body and and and 34:48 that's one of the most important things besides your diet for regulating inflammation you talked about stress when you sit 34:56 down with your patients and you talk to them about their lifestyle what are the biggest 35:03 contributors that you see over and over again top level that are 35:09 the big factors that drive chronic stress individually from patients you know what is it is the relationship is the lack of 35:16 meaning and purpose like what are the things that are out there that you see time and time again that are really the drivers of the stress that everybody's 35:22 dealing with it's a great question you know why are some people more resilient than others why does people roll with 35:28 the punches and others just get completely knocked off center and one of the things we use in our practice at cleveland clinic and lennox 35:34 and the ultra wellness center is called the ace questionnaire or adverse childhood events and it's essentially a set of 10 35:41 questions or so that you get a score for that tracks trauma were you abused as a child where you 35:47 unsafe just a whole series of questions that help understand if as a child you experience 35:53 lack of safety or worse abuse trauma incest so forth the higher score 36:00 the more chronic disease risk you have the more inflammation risk you have the more likely you are to have autoimmune disease to have allergies to have 36:07 chronic illness so looking at someone's childhood is so 36:12 important and those impacts of trauma and i think we're just beginning to understand how widespread that is and 36:19 you know for example one in four americans is a victim of sexual abuse as a child 36:24 think about that one in four americans it's like 80 million people 36:30 that's a lot of people okay um i wonder if that's the 80 million that has autoimmune disease i don't know 36:35 but it might be and so as you begin to look at how do we manage the inflammation 36:41 response that's the first place i start and then and then i look at how do people 36:48 navigate their minds because your mindset plays a huge role in chronic disease and so 36:56 if you're able to regulate your thoughts if you're able to not be constantly triggered and activated by your 37:01 environment if you're able to have a level of equanimity which can be cultivated and developed through 37:08 practice right that's what meditation does and yoga does and prayer does and there's a whole series of practices of 37:14 whatever calls to you that you can do that really helps to reduce the 37:19 level of stress in your system if you don't learn how to do those things then you just you just kind of 37:25 have this unregulated unmitigated stress response that drives so much chronic disease that keeps you inflamed so yes i 37:32 mean we have to one look at the original sources and we have to look at you know how we navigate 37:38 our lives and how our our thoughts are and how our relationships are and how our community is and so there are a lot 37:44 of ways to work through that and i think it's so important for people to understand that they need to build the structures in their life 37:50 that are constantly battling inflammation so what is that for me 37:56 it's it's basic practices that i do i meditate every day i exercise i eat an inflammatory diet i take the supplements 38:03 that help my gut microbiome stay healthy i make sure i have low levels of toxins that i'm exposed to i make sure i 38:09 connect with people i love build community have deep relationships that's to me what i do to mitigate and 38:17 to discharge the stress and inflammation because if you if you don't intentionally do it uh it just accumulates and uh and it's 38:24 tough because we we are live in a bubble so it's sort of like being in the truman show we don't even know we're in it we're just victims of or in the matrix 38:30 and we don't know we're in it so how do you get out of that and go okay i'm just going to pause for a minute and kind of 38:35 reset and i think that's a really important set of practices that we can all be doing and it can be fun it 38:40 doesn't have to be difficult or stressful one of my favorite is is hot and cold therapies so sauna steam ice 38:47 plunge it's amazing for discharging stress literally your whole system will will sort of reset i remember 38:54 working in uh residency and you know we had an enlightened residency where we only had to work 30 hours in a 39:00 row not 36 hours i would get off noon the day after call 39:05 and i'd drive up to this hot springs in california and i would soak in the hot springs and then i would go in the ice pool and the hospital was super hot and 39:12 icing was super cold and it'll go back and forth back and forth and i just know all my fatigue all my stress from 39:19 working on the hospital and the call and the trauma just would go away and i would like reset and you know now it's a 39:25 thing but back then we just kind of was weird but it's so powerful so you have to learn 39:30 for yourself one of those things that you can incorporate that you like into your life on a daily basis that help regulate you 39:36 let's go back to the gut microbiome you listed it as one of the top things that a disrupted gut microbiome 39:43 or a dysregulated gut microbiome is one of the key drivers of inflammation 39:48 you have in your lifetime on multiple occasions had a gut that's been messed up right we won't get into the whole 39:54 journey we made a couple documentaries about it if people want to watch them they're at drhymon.complus 39:59 sign up for a free trial you could watch them broken brain longevity docu series we've talked about them all yeah but 40:04 high level what was missing for you when your gut 40:10 was dysregulated and how did you begin to take the steps to bring it back into repair 40:16 i mean i you know i didn't have the usual things i was always a weirdo so for me 40:22 um the first time was mercury poisoning and mercury is 40:28 powerfully damaging to the gut it will bind to all the enzymes it'll cause leaky gut and it creates bad bugs 40:34 growing and yeast overgrowth so for me i developed you know chronic diarrhea 40:41 bloating irritable bowel bacterial overgrowth fungal overgrowth 40:46 and and that was really really really hard to treat until i got the mercury down that was my first foray into bad 40:52 gut then i kind of corrected it after i got the mercury out and rebuilt my gut and then about five years ago 41:00 i had a bad tooth and ended up having a root canal the root canal went bad got the tooth 41:06 pulled and the dentist who was a holistic dentist said you better take this antibiotic 41:11 and i'm like okay and i just was a little nervous about it and it's a particular antibiotic that's great for dental infections called 41:17 clindamycin but it's also the biggest cause of what we call c difficile which 41:23 is a terrible intestinal infection that kills 30 000 people a year very difficult to treat and they're 41:29 using fecal transplants to treat it almost 100 cure and the typical antibiotics that are used don't work 41:36 that well so i basically developed c difficile which was a terrible intestinal infection colitis and that 41:41 caused colitis and then that developed into inflammatory bowel disease i was having 20 bloody bowel movements a day 41:48 severe pain i mean it was just i lost 30 pounds it was it was bad and all my normal tricks didn't work 41:55 why because my whole system was so screwed up by the mold in my house 42:00 and by this infection that took over that even even taking prednisone didn't 42:05 work and i was you know next step was taking a biologic and i didn't want to do that 42:10 and so i began to sort of figure out how do i really reset my system and sometimes you just 42:16 need a powerful set of tools to drive the body out of a stuck inflammatory cycle 42:23 and i based on my experience in the science and what i understood i use a combination of things that just 42:29 const just almost immediately flipped my system one was ozone therapy that was hyperbaric oxygen therapy i use high 42:36 dose intravenous vitamins and vitamin c and also stem cells and those four 42:41 things and exosomes those four things really flip my system out of this stuck 42:47 inflammatory cycle but that was weird and that's rare and most people i don't need to do that with but i'm a weirdo so 42:53 i i get all the worst of everything and i have to figure it out and then i you know kind of learn how to sort of make 42:59 my body work better well one of the unique things that came out of that is that once you got your system back to baseline and it was really bad right it 43:06 was really bad we've talked about that before but once you got it back to baseline you went down this whole rabbit hole of how the power of phytochemicals 43:13 as you talked about earlier phytonutrients phytochemicals these plant compounds uh on a regular basis can help you 43:20 maintain this level of where you're at so talk to us about it yeah so how is this that food is really information in 43:26 this category of phytochemicals yeah so so for decades we've known that 43:31 prebiotic fibers are healthy and prebiotic foods are healthy what is a prebiotic it's something that feeds the 43:36 good bacteria so it could be various kinds of fibers that are in plant foods special foods like artichokes asparagus 43:43 plantains jerusalem artichokes all have these special fibers that are 43:49 really good food for the microbiome also the probiotics are important to probiotics 43:55 and there's all kinds of strains we also knew that that that that we need to make sure we have 44:01 the the right amount of of of just general fiber as well so those are those are things we understood 44:08 but what i didn't understand was the importance of the phytochemicals in food to feed the good 44:15 bugs because not only do they eat the fiber but they also are stimulated and love certain phytochemicals for example 44:22 there's a really important bacteria that i had almost none of which is called acromancia muciniphilia 44:28 mucinophilia means mucin loving right mucin is mucus why do you have that well you want to 44:34 protect your intestinal lining and not get a leaky gut so your back this bacteria creates this incredible thick 44:41 mucous layer that prevents bad stuff from getting in but if you don't have this bacteria you can't get that well 44:48 when i had this problem you couldn't actually take a necromancy or probiotic now they have them 44:54 but acromancial love polyphenols which are these colorful 44:59 compounds in fruits and vegetables they love cranberry they love pomegranate they love green tea they love curcumin they have all these 45:06 incredible plant compounds and so that was a huge insight so we need prebiotics probiotics and polyphenols to create a 45:13 healthy gut which is why eating a colorful diet is so important 45:19 beautiful and you've written about acromancia we'll link to the blog post that you have there you even talk a little bit about this kind of shake 45:26 which includes uh pomegranate concentrate and a bunch of other things yeah cranberry and green tea so we'll 45:31 link to that as well that really helped me by the way that really helped me reset my gut i created this cocktail of stuff that was designed to 45:39 incorporate all the knowledge that i had over 30 years of functional medicine it was a lot of different things in little 45:44 containers and things we've now created something called gut food which will soon be available on getpharmacy.com 45:50 which combines all these things into one simple powder that you can mix in water 45:55 or in something else and actually consume it and it will help to provide the food for your gut we're calling it 46:00 gut food let's talk about testing when it comes to inflammation are there tests that you use and 46:07 recommend both with patients that you work with but also if people don't have access to a functional medicine doctor 46:13 are there tests that you recommend they ask their doctor for to help them 46:18 understand how inflamed they are yeah i mean there's two aspects to this one is checking for inflammation to see if 46:24 you're inflamed and then checking for why you have inflammation it's two different things so while 46:30 inflammation may be imbalances in your gut flora it may be toxins it may be allergens it may be your diet it may be 46:36 stress right so we have to go down those rabbit holes in terms of the actual measure of inflammation 46:41 we're getting much more sophisticated about it so there's a common test that your doctor can do called c-reactive 46:46 protein and that's really important has to be a high sensitivity c-reactive protein that can help you determine if there's a 46:52 generalized level of inflammation it's good but it's not perfect then there's a sedimentation rate which is an 46:58 age-old test it looks at how long it takes your blood to settle if it's got a lot of inflammatory proteins it's done and settled in the test tube very fast 47:04 that can be a sign so there's there's common things we use we can also look at cytokines you can look at interleukins 47:10 and and we can look at two necrosis factor alpha and other biomarkers of inflammation 47:16 but that's just scratching the surface there's a whole as i mentioned earlier there's this scientist at stanford who's 47:21 measured these unique analytes in your blood that doctors 47:26 normally don't test that are the most predictive of aging and chronic disease so we should probably be testing things 47:33 like that so those are the ways we kind of measure inflammation we can also look at auto antibodies we can look at 47:38 allergens we can look at immunoglobulin levels there's a lot of ways we can look at what's going on with the immune system we look at t cell function and 47:44 lots of things so the basic tests are available through conventional medicine but the key is not just seeing if you're 47:50 inflamed the key is to ask why you're inflamed and then go down the rabbit holes of looking for the causes 47:57 can you share a case study from your practice of anybody because we have so 48:02 many different names for modern diseases that are driven by inflammation but if you can think of one person who had the 48:08 right mixture of a lot of different root factors that you helped and worked with to get their inflammation under control 48:16 and then get back to health absolutely i'm just thinking of 48:21 so many patients that are flooding my brain right now but i'll just share one story of a woman with 48:27 rheumatoid arthritis terrible migraines and a lot of gut issues 48:33 and you know typically she was seeing her rheumatologist and getting all the rheumatology drugs and really struggling 48:40 and so i said well okay these are all inflammatory problems migraines gut issues rheumatoid arthritis let's look 48:46 and see what's causing it so it turned out she had very high antibodies to gluten so she was gluten sensitive 48:52 and quite significantly she had bacterial overgrowth in her gut and she had super heavy metals 48:58 so systematically i got gluten out of her diet i healed her gut i got rid of the heavy metals 49:05 and she had complete recovery and all the things that were abnormal her c-reactive 49:10 protein her rheumatoid arthritis antibodies her my her migraines her her leaky gut 49:16 all normalized and now it's 20 years later and she's still amazing and 49:22 got rid of all those diagnoses because they were all caused by inflammation 49:27 you talked about diet you talked about additional therapies like sauna hot and cold other things like that we talked 49:33 about exercise talk about supplementation how does it play a role and how could it be helpful on the topic 49:39 of inflammation well you know just the most basic things can be helpful right so there was a study 49:44 published that showed that if you take a multivitamin your c-reactive protein level goes down which is awesome but 49:50 that's just one thing and and what is the mechanism of that that you think yeah so we we have a similar body to 49:56 control inflammation and that system requires nutrients and many of us are nutrient depleted so for example a 50:02 multivitamin will reduce c-reactive protein and it does so by activating all sorts of enzymes cool so vitamin what 50:08 are vitamins minerals they're basically helpers one-third of your entire dna codes for enzymes what enzymes do they 50:13 turn one molecule to another molecule one chemical to another chemical in your body and all the enzymes we nee we have 50:20 required coenzymes or cofactors helpers and what are those those are vitamins and minerals and so 50:26 some of us need a lot more of this one or that one and if we're low which a lot of us are this is not my opinion this has been the 50:33 government's own surveys and diagnostic testing and giant studies of tens and tens of thousands of people that over 50:40 ninety percent of americans are deficient in one or more nutrients at the minimum level you need to prevent 50:46 deficiency disease so not how much you need for optimal health or immune function but how much vitamin d you need 50:52 to not get scurvy i mean to not get rickets not very much how much vitamin c do you need to not get scurvy not very 50:58 much but how much vitamin c or vitamin d you need to regulate your immune system and reduce inflammation 51:03 a lot more so many of us are deficient in nutrients so that's the mechanism and then there's 51:08 specific nutrients that are really important inflammation omega-3 fats number one 51:14 we need the omega-3 fats like ep and dj that typically come from fish oil we need the 51:20 uh vitamin d levels to be adequate uh and and not low because vitamin d 51:26 regulates hundreds of genes that regulate inflammation we need to make sure we have adequate 51:31 amounts of things that help to boost detoxifying compounds in your body like glutathione 51:38 which comes from the for example broccoli family when you eat these compounds they help to 51:43 increase glutathione but also you can take for supplements to do that like n-acetyl cysteine which i think the 51:48 government is is now restricting in some ways which makes me very nervous but this is a substance we've used for 51:54 you know a long time decades and decades since i've been in medical school in medicine as a therapy to 52:00 help recover people from tolerant overdose and liver failure from kidney failure from dye contrasts and many 52:05 other things so for asthma and lung inflammation so it's one of the most powerful anti-inflammatories in our body so i take supplements to increase 52:12 glutathione which really helps so there's a there's a few things we can do strategically and then of course there's things like curcumin 52:18 and there's polyphenol supplements and and various other things you can take but but those are the most important 52:23 you wanna know my secrets for living a long and happy and healthy life well all i have to do is check out my weekly 52:29 newsletter mark's picks where i share my favorite tips for health longevity well-being and lots more check it out 52:36 and the link below talk to us about the role that fasting plays fasting in all its different forms when 52:42 it comes to chronic inflammation that plagues so many people yeah 52:48 so our bodies were designed to deal with scarcity and we have hundreds of genes 52:54 that help control starvation and put our bodies in a healing and 53:00 repair state when we are lacking food 53:05 we have almost no genes that help us deal with abundance in excess like the 500 extra calories of corn syrup that 53:11 every american is exposed to since 1970. so 53:17 when we are in a state of scarcity our bodies kick into action a whole set of 53:22 mechanisms that reduce inflammation that increase antioxidant systems that build muscle that get rid of fat 53:29 burn fat which is good in the case of starvation and that help to increase stem cell function 53:34 and and many many other beneficial factors improve mitochondrial health clean up your cells get rid of waste i 53:40 mean it's just it's quite amazing what happens when you have scarcity when you starve which is a good thing because you you 53:46 want to keep alive as long as possible so everything is in your body is like i'm just going to fix everything so i 53:51 don't die so how do you get to that state well there's a lot of techniques that are now 53:56 being talked about and they all have the same mechanisms whether it's time restricted eating which is eating within 54:02 an eight hour or ten hour 12 hour window whether it's intermittent fasting which is having a 24 32 hour fast once a week 54:08 or more prolonged fast whether it's fasting making diets which are calorie restricted diets for five days of 800 54:15 calories whether it's a ketogenic diet which restricts carbs and increases fat 54:21 that's actually what we get in when we're not eating we get in a ketogenic diet when we don't have food our bodies go in ketosis but you can do that by 54:28 eating more fat so all those ways of eating actually activate the body's own healing 54:34 mechanism what happens well you reduce inflammation you increase antioxidant systems you increase stem cell 54:39 production you increase muscle you increase bone density you increase cognitive function and brain chemistry 54:44 and neuroplasticity you do all these things simply by activating these ancient healing systems 54:50 that are designed to protect us from starvation so it's kind of like controlled starvation 54:56 in a way and that's a good thing and i think it's really it's really important for us to think about how we do those things on a regular basis and i try to 55:02 incorporate those strategies regularly in my life so now we're gonna go to our community 55:08 our youtube comments our facebook comments instagram and podcast community that emailed in we're gonna take a few 55:15 questions here and we're gonna start off with the first one and the first one we have here is what role do grains play 55:22 when it comes to inflammation chronic inflammation in the body can grains help 55:28 or hurt chronic inflammations in the body great question depends on the grain 55:33 white flour surely is one of the most inflammatory foods on the planet whereas ancient grains like himalayan tartary 55:40 buckwheat may be one of the most anti-inflammatory foods on the planet so it's not grains as a whole it's which 55:47 grains in what form how are they grown where were they grown what were they grown with are they full of pesticides 55:52 are they full of glyphosate i mean there's there's so many layers of things that will actually determine the answer to that question 55:57 in general though the way we eat grains in this country is as white flour 56:03 90 of the grains we eat in this country is white flour very few people eat whole grain foods um 56:10 maybe there's a whole wheat bread but if you look at the label it's mostly white flour with high fructose corn 56:16 syrup with a few flakes of whole wheat thrown in there right it's not it's not like the dense breads you get in europe 56:21 or germany so i i'm not against grains but i do think that there are are challenges for people who are a lot 56:27 eating a lot of flowers probably one of the most inflammatory foods and if you have a leaky gut if you have 56:33 an imbalance in your microbiome if you're not having an intact system in your gut 56:39 it grains can be a problem so i tend to eliminate grains if i'm really aggressively trying to reduce 56:45 inflammation not forever but for a short period of time to try to reset the system to heal the leaky gut and get 56:50 people functional again and if you if you if you do that you you also do a 56:55 number of other things because grains are starch and depend on how much you eat right having a half a cup of black 57:01 rice or a half a cup of buckwheat may not be a problem but typically we 57:06 eat huge amounts of grains and that drives another pathway for inflammation 57:11 which is insulin resistance or pre-diabetes or blood sugar problems and so we we have to understand that we have 57:17 to reduce the starch and sugar in our diet and one way that is is actually reducing grains but whole grains can be 57:23 a part of a healthy diet it's just when you get to eat them who gets to eat them in what context with what other 57:28 foods and where those grains come from and are they you know modern hybridized grains that 57:34 are full of starch and sugar or are they ancient grains that have all these phytochemicals and other beneficial properties 57:41 next question how does hormonal balance or imbalance related to inflammation 57:48 so the biggest driver of chronic inflammation is stress which 57:53 drives all kinds of hormonal dysregulation it screws up your hormones the sex hormones your insulin 58:00 blood sugar uh cortisol adrenaline and and it really drives huge amounts of inflammation so 58:06 if if you are actually are are highly stressed that will drive a lot of the pathology i mean insulin is 58:13 another hormone that is a big one that drives inflammation that's one of the biggest ones we talked a lot about that you'll see people who are taking 58:19 hormones for example estrogen or the birth control pill and and depends on what you're taking if 58:25 you're taking for example premarin it raises inflammation in the body it causes a high crp 58:30 so does the birth control pill so a lot of people are taking the birth control pill i'm not saying people should stop birth control pill but you 58:37 want to make sure you mitigate the effects of that and i recently did an instagram live with the founder of even 58:45 sarah morgan talking about the ways in which for example medications deplete nutrients 58:51 and affect the body adversely so for example if you're on the pill the birth control pill you may need to take 58:56 certain nutrients to mitigate the effects of that and help reduce inflammation so certain things i would never take like premarin 59:02 which is a hormone that drives inflammation but i i certainly wouldn't tell everybody to stop the birth control pill but i think you have to know what 59:08 you're doing and actually offset the harm by taking the right nutrients to to actually mitigate the damage and the 59:14 inflammation that comes from that last question here before we go into final thoughts and conclusions can 59:19 inflammation be tied to our genetics are some people more prone to 59:25 developing markers of inflammation especially chronic inflammation absolutely i mean we're all heterogeneous you know we 59:33 have 20 000 genes we have about 5 million variations in those genes and some of those variations predispose you to inflammation and we test those i do 59:40 that in my actual practice looking at saliva 59:47 swabs that measure dna and we can look for variations in certain genes that affect 59:52 the cytokines like interleukins and cnf alphonse other genes and we can see oh 59:57 you're someone who if you get some trigger is way more likely to be inflamed 1:00:02 so there are people who are predisposed inflammation but that doesn't mean they're predestined to inflammation 1:00:09 so they need to identify one the sources of inflammation in their life and get rid of them we've talked about those and they need to include 1:00:16 anti-inflammatory strategies in their life an anti-inflammatory diet more polyphenols probiotics antioxidants and 1:00:24 obviously other anti-inflammatory strategies like adequate sleep and exercise and stress reduction so forth 1:00:30 so hot and cold therapies we just need to upregulate the anti-inflammatory system and calm down the inflammatory 1:00:36 system so yes there are people who are genetically predisposed but it doesn't mean they're predestined 1:00:41 so not everybody will have access to a functional medicine doctor obviously if they do that's fantastic and amazing you can go to ifm.org and find somebody in 1:00:48 your area it is often expensive insurance doesn't cover it but it's and it's not available 1:00:54 to everybody but if you can it's a great thing if you can't and for example they wanted to explore the topic of genetics 1:01:00 a lot of people have 23andme data are there any of those websites that you like or would recommend to people that 1:01:06 they can plug in their raw data and get back some of these unique markers that 1:01:11 they have to pay attention for their own genetics i mean there are uh is a genetic genie 1:01:17 which is sort of a interpretive guide where you can plug in your 23andme data which can be helpful for looking for 1:01:22 problems with methylation and glutathione and detoxification and some of the inflammation genes uh 23andme 1:01:28 only does a small slice of your genome it doesn't look at everything so uh we do more clinical testing uh and i tend to 1:01:36 do that and focus on that so there may be there's so much going on right now in the space i may not be familiar with it but there probably are companies that 1:01:42 are looking at inflammatory genes that are available to consumers the question is when you do that information and i think 1:01:48 that's the challenge for people so how do you change your diet what supplements you take what do you avoid i mean it gets a little granular so it's usually 1:01:55 better to work with someone who's experienced to understand these tests how to mitigate your risk and to to create a lifestyle 1:02:01 that actually helps to reduce inflammation if you loved that last video you're gonna love the next one check it out 1:02:07 here healthspan is how many years you're alive that you're healthy and lifespan is how many years you're alive 1:02:13 so if you spend you know the first 50 years healthy and then 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Typically, inflammation has been raging inside for a while before you even notice there’s anything wrong. The three biggest drivers of inflammation are : gut health, diet, and chronic stress. In this episode of my new Masterclass series, I am interviewed by my good friend and podcast host, Dhru Purohit, about inflammation, what’s causing it, and how to reduce it. We discuss the critical component of gut health and how 60-70% of our immune system is in our gut, as well as tests to identify inflammation in the body, foods to avoid, and the importance of restful sleep. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, Dhru Purohit Podcast, is a top 50 global health podcast with over 30+ million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. This episode is brought to you by Rupa Health and Athletic Greens. Rupa Health is a place for Functional Medicine practitioners to access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, Great Plains, and more. Check out a free live demo with a Q&A or create an account https://rupahealth.com/. Right now, Athletic Greens is offering my listeners 10 free travel packs of AG1 when you make your first purchase. Just go to http://athleticgreens.com/hyman to take advantage of this great offer. Key moments View all Explore the podcast 543 episodes The Doctor's Farmacy with Mark Hyman M.D. Mark Hyman, MD Podcasts Transcript Follow along using the transcript. Show transcript Mark Hyman, MD 1.09M subscribers Videos About 1:15:06 DOCTOR REVEALS How She Cured Her Autoimmune DISEASE! | Cynthia Li & Mark Hyman by Mark Hyman, MD 1:14:55 The 5 STEPS To Reduce BRAIN INFLAMMATION Today! | Mark Hyman by Mark Hyman, MD 56:35 Doctor Thinks He Knows What Causes Alzheimer’s, Parkinson’s, and ALS! | Mark Hyman by Mark Hyman, MD 1:15:04 My DAILY HACKS To Improve Sleep, Destroy Laziness & LIVE LONGER! | Andrew Huberman & Mark Hyman by Mark Hyman, MD 648 Comments rongmaw lin Add a comment... @IIETMII @IIETMII 3 weeks ago (edited) This has to be one of the most interesting, fascinating, comprehensively informative conversations I’ve ever heard on health before. Thank you so much ❤ 5 Reply @kamlaprasad1510 @kamlaprasad1510 8 months ago Beautifully laid out so we can all listen to our own body, and help ourselves to recover from some of the symptoms we suffer from. Thank you so much. A lot to learn from. 44 Reply 1 reply @BroccoliRocks @BroccoliRocks 1 year ago 1. Gut health issues - an unhealthy microbiome 2. Eating too much sugar and starch. Having too much belly fat. 3. Chronic stress 352 Reply 17 replies @wilmingtonvoicecoach @wilmingtonvoicecoach 9 months ago Let's not forget that mental health and the stress response mind to body is actually the beginning of kicking this whole thing off. Resentments, regrets, anger, self pity, victim trips, etc....start there first and see the body change. The food choices and all other things I believe are symptoms of the mental/emotional and belief systems most of the time. People don't want to sit in their skin, they are running from themselves, their past, and their life. That has to be addressed first. -Nyla Cione. 236 Reply 15 replies @judyknight3149 @judyknight3149 3 months ago I was in an early test group online 12-15 years ago. It changed my life. Labeling food ingredients is so tricky. I still have to be very careful. Glad you are using this site since censorship is happening to medical advice on other channels. Your ideas are pretty radical and are changing what people eat. 21 Reply @AJ_411 @AJ_411 1 month ago Great information. Surprised you didn't mention the importance of knowing your foundational genetic makeup because it starts there even for inflammation. If you're predisposed to chronic inflammation at the gene root level and then stack on poor diet and stressors, you're setting up the perfect storm for autoimmune disorders. Knowing where and what variants are causing or contributing to issues allows you to better address (and counter) them. 4 Reply 1 reply @erlesefrazier7698 @erlesefrazier7698 1 year ago Thank you Dr. Mark Hyman. You are doing a great service to the world. 65 Reply @kiki19822 @kiki19822 2 years ago Fabulous interview. Sent it to so many of my family and friends. Health begins in our gut. 94 Reply 3 replies @carolferguson19 @carolferguson19 2 months ago Wow the inflammation of the brain makes sense. Stress causing inflammation is exactly right as I have experienced it. I have Fibromyalgia and Lupus 38 years now half my life. Ten years ago I had a Cardiomyopathy from stress and have had very HBP lately 254/154 from stress. Getting it lower mentally and physically little by little. Like my dad used to say "Don't sweat the small stuff 💕🙏 39 Reply 3 replies @motherbear327 @motherbear327 4 months ago It's so goood to hear that Dr. Hyman uses the ACE's questionaire in his practice. Also that he focuses on mindset. I wish more doctors would do that. It's so important to look at the whole picture when it comes to our health. :) 12 Reply @catharinealexander89 @catharinealexander89 1 year ago Amazing interview. Such a wealth of knowledge. Thank you for sharing all of this information with us!! 24 Reply @susisjardin2459 @susisjardin2459 1 year ago Thank you Dr Hyman. A great video as always, your expertise is changing people’s lives daily, including mine. 16 Reply @RonBoucher-ll1go @RonBoucher-ll1go 2 months ago Love this Dr....whenever I'm stressed I love listening to him...he calms me down...❤ 10 Reply @myriammadigan9966 @myriammadigan9966 2 years ago Thank you so much - this is a brilliant interview. Broad, intelligent and clearly presented. 24 Reply @noraal2560 @noraal2560 2 years ago I’m a firm believer in this basic concept that is not going to be changed. All disease can be narrowed down to inflammation. Many of it can be searched for its aetiology in gut as it is the easiest access for external factors. I agree. 24 Reply 1 reply @alinamcallister7819 @alinamcallister7819 3 months ago Grounding also helped with inflammation in the body, which is something we all need to do more of ❤ Who doesn’t feel more amazing while being at the beach without shoes ?! 16 Reply 3 replies @alipainting @alipainting 1 year ago This talk contains as much info as an entire book. Thank you Dr Hyman 😄🤗😊 33 Reply @89190jprice @89190jprice 8 months ago (edited) This is an amazing podcast/interview, wow. Such thoughtful questions and helpful answers! I have Psoriatic Arthritis. The psoriasis is on my elbows and knees, scalp and my achilles heel and bursa has been inflamed for 2 years. Doctors just want me to take these harmful drugs and I'm thinking the answer is strict diet. It's just so hard to develop the discipline and I need to put faith in eating healthy and non processed foods. 40 Reply 7 replies @dandamerville @dandamerville 2 years ago Beginning around 9:30, while discussing how stress arising from social negativity is a driver of inflammation, Dr. H says "nobody knows how to train their brain." He then says such training is the subject of another podcast. Learning to regulate one's feelings towards others is also the subject of all the world's great religions (and, I'm sure, many of the smaller ones), along the lines of "Love thy neighbor as thyself." 54 Reply 1 reply @leanneporter3408 @leanneporter3408 3 months ago Thank you so much for all that you do, Dr. Hyman! Wonderful info Reply @deanmorelli783 @deanmorelli783 3 months ago I have found this interview to be profoundly transformative. The way in which diet and health are put in a socio political context is incredibly provocative. Thank you for your insights. They are most valuable. 4 Reply @blankslate6393 @blankslate6393 1 year ago Excellent informative talk by Dr Hyman, and also clever question. Thanks guys. Learned a ton. 8 Reply @JohnnySahn @JohnnySahn 6 months ago @28:00 I like how Dr. Hyman breaks it down. If you don't recognize the ingredient then don 't eat it. Plain and simple. Thank you sir for your service to humanity! 12 Reply @A_Changed_Heart_Ministries @A_Changed_Heart_Ministries 8 months ago Thanks so much for sharing your wisdom with us 😊🙏🏼 3 Reply @bettyharrison9537 @bettyharrison9537 3 months ago Thank you for discussing the damage that is being done to our children through targeted advertising. The issue is more important than anyone realizes. 4 Reply @faithsteinberg3349 @faithsteinberg3349 2 years ago I am a 90 yr. old woman who has taken care of herself for most of her life--doing my own cooking, using organic.foods, negligible sugar and salt. I exercise daily. My problem is arthritis in the lumbar region of the back. My last blood test was surprisingly excellent. I exercise daily. But the pains debilitate me. Your comments would be greatly appreciated. Enjoy your talks. Thanks, Faith 124 Reply 33 replies @joannawilson8523 @joannawilson8523 2 years ago Thank you Dr. Hyman for this information. You mentioned you had stem cell therapy for your colitis. Where or what kind of doctor can do this & what is the expense? I have read about stem cell therapy & it seems to be the key to treating & healing auto immune diseases. 13 Reply @drkmlakshmipathy @drkmlakshmipathy 2 years ago Controlling Brain and mental activity is not easy as other organs in our body ..so understanding the deep secret of traditional meditation and yoga are able give some easy steps to control Brain activity and mind....this is what Dr Mark mentioned that hatred violence sarrounding influences of social ,political and economical social security etc all contribute to hidden inflammation in our body..I love Dr Mark smile they way explain these complete truth in a simple words . Thank you for this educative video .lots of regards and ❤️from Chennai India 🙏 11 Reply @keeplookingup1111 @keeplookingup1111 5 months ago 9:05 - Wow. Positive , happy social coversations and thoughts turn on genes that kill inflammation . Social conversations that are negative or have conflict in word or even in THOUGHTS turn on genes that create inflammation. 11 Reply @SaturdaySoul @SaturdaySoul 3 weeks ago (edited) I have had chronic gut inflammation my whole life and not one doctor had ever been able to tell me why. I had a voluntary hysterectomy because of the pain. I feel like I'm going to die and nobody can help me. I didn't even know it was inflammation until a few of years ago. It's followed me no matter what my weight or diet has been. 2 Reply 1 reply @shanonkulkin3040 @shanonkulkin3040 6 months ago Thanks so much!! You are the opposite of those blankety blanks making money off people’s pain. Yoga, meditation, prayer and surrounding yourself with beautiful kind people is the way to go!! ❤ 21 Reply 1 reply @luccarre5155 @luccarre5155 4 months ago Thank you so much Mark for all your videos. God bless you 🙂 7 Reply @mariawelling4194 @mariawelling4194 3 months ago I love it when Dr. Hyman gets passionate. He speaks from his knowledge and experience. 2 Reply @ditadee01 @ditadee01 3 weeks ago 💯 agree the advertising & algorithms for inflammatory products is harming society, imagine a world that promoted nature & healthy foods & methods to grow foods.. we are not progressing as a society in this respect we are regressing… in a drastic and scary way… thank you Mark for your amazing work my family are farmers in the UK for many generations so I’ve always understood the importance of food & how it’s grown in synergy with nature.. Please support farmers & natural farming methods this are basics we cannot live without 🙏🏼🥕🥦🌟 Reply @sirenorebello817 @sirenorebello817 5 days ago God bless this great doctor Mr. MARK for his great information & goodness 🙏 Reply @lovingitonketo @lovingitonketo 2 years ago (Harry here) I'm dealing with a bad hip and I know that inflammation is causing most of the pain. I'm familiar with a lot of the information you've talked about in this video and I'm going to try and turn it up a bit to see if it might help with a little relief until they can get in there and fix itr. I'm not real happy about how the hospitals are not letting your loved ones to come into the hospital and be with you during stays. I was hoping to hold off on doing the operation in hopes of the restrictions being relaxed. I can't see going into the hospital alone and dealing with this alone. We all need our families for recuperation. I was wondering what other people's thoughts are on the current situation and dealing with loved ones in hospitals. If I could control more of the inflammation, I believe I could hold off a bit longer but sometimes the pain is just to much. 11 Reply 4 replies @christelnielandt5117 @christelnielandt5117 2 months ago Outstanding conversation. LOVED ALL of it 🙏🙏🙏🌟🌟🌟 Reply @lmust2 @lmust2 1 year ago With covid causing clotting, I have seen many people with PE's during or right after covid infections. I believe leaving people on baby aspirin just a little longer until covid 19 either goes away or becomes seasonal, is a good idea. Most of my patients do not follow anti inflammatory diets and are full of plaque in their later years. Your thoughts on this or alternatives for those people? 6 Reply 2 replies @sharonmagdalenebooysen2874 @sharonmagdalenebooysen2874 9 months ago Thank you so much ❣️ for a helpful information, Dr Mark ‼️ inflammation start in my gut 😳 5 Reply @paulaistrate4628 @paulaistrate4628 2 years ago I am 43 years old and I have AS and IBD since 4 years ago, I suffer from horible pains at my sacroiliac joints, my reumathologist said I can never be cured but I started to watch wonderful videos from Dr Mark, Dr Eric , Dr Steven and more, I hope I will find some releif because I am depressed 25 Reply 7 replies @KaleidoscopeMagic @KaleidoscopeMagic 8 months ago Finally, here is a doctor that I think I could trust and respect and actually BENEFIT from listening to and following his advice. KUDOS! 8 Reply @Astri-ez9wx @Astri-ez9wx 5 months ago i like how you explain about inflammation. last time I just did a seminar about it. and I cant agree more with you about it. in Indonesia, we still don't know that degeneration of organs is the cause of chronic inflammation. 1 Reply @petergraham8415 @petergraham8415 2 years ago This man has answered for me what I have been trying to know. I knew source of inflammation in my body. Not the why? Of cause and affects. Gives me impetus to bounce back. 9 Reply 1 reply @derekp.1516 @derekp.1516 2 years ago What is your advice for long haulers who are trying their best with natural remedies to calm inflammation but not recovering? I love the idea of natural way and supplements without medications. I was previously functioning and in good health before covid. With low mood, not feeling myself, exercise intolerance that has gone on for such a long time now I would be open to at least trying some medications put out by the FLCCC such as fluvoxamine which has some anti inflammatory properties. What is your opinion in long haul covid if patients aren’t gaining enough improvement naturally? 12 Reply 8 replies @drkmlakshmipathy @drkmlakshmipathy 2 years ago Great information about hidden inflammation in gut..thank u 🙏 15 Reply @vickiebonawitz5611 @vickiebonawitz5611 2 months ago I have seen exactly what he is talking about and a functional doctor helped my daughter improve step by step. 2 Reply @whitevoodooman7276 @whitevoodooman7276 2 years ago I've had to find out the hard way that what your saying is well and truely true Good work mark 5 Reply @ByDesign333 @ByDesign333 2 years ago (edited) The big Framingham Study went from blaming dietary cholesterol for arterial blockage to blaming inflammation only. Both my cardio doctors read the article I shared with them, but only one halfway agreed with the study...but both still say "take the statins"....which I don't. (I had triple bypass 6 years ago) 15 Reply 2 replies @jayaverma3993 @jayaverma3993 1 year ago Social structures and present day divisiveness, social oppression, social inequality, ongoing covid crisis, social conflict is inflammatory. Present covid crisis is creating mental health issues...wonderful analysis and good advise on what we can do on food, gut microbiome, but difficult to deal with macrocosm of conflict and divisiveness.. Need more meditation and spiritual practices to be more mindful about sustainable food, our community connection and contribution to society, and how we can sustain our earth 8 Reply 1 reply @Beckelbay @Beckelbay 1 year ago @MarkHyman,MD I was a patient at the CCF FM clinic here in Cleveland. Worked for three visits with a NP who was very knowledgeable. I loved the direction we were going and I was beginning to see results, but it was sooooo difficult to get appts. The NP would want me to come back in 6-8 weeks but the appts were being made for 6-8 months out. I found that to be quite discouraging. I tried to keep up with what I knew to do, and still do, but I stopped going back. Any thoughts? 2 Reply 1 reply @PhilosophiesofEverydayLife @PhilosophiesofEverydayLife 1 month ago Thank you so much! I needed this valuable information! I came to your video and much needed information. This is God's answer for me! Thank you, thank you. Reply @arpigracetarkhanian9684 @arpigracetarkhanian9684 1 year ago Divine wisdom 🙏 3 Reply @jenna.w.9041 @jenna.w.9041 2 years ago My Husband was diagnosed with Alpha Gal syndrome in May 2021, and Acquired Angio Edema in August. To make matters worse he underwent emergency quadruple bypass a year ago in July. At this point we are at our wits-end trying to figure out what is causing the angio edema! I have tried to find a toxicologist to analyze the MSDS of the chemicals he is around at the machine shop he works at with no success. Do you have any recommendations? 2 Reply 1 reply @bluewaterwomen @bluewaterwomen 1 year ago Every day I make a tea with boiling sliced turmeric, cinnamon, star anise, cloves, ginger, strain add coconut mil and a dash of honey. No joint pains ever at 76. And tasty! 616 Reply 76 replies @brendamcchristy6044 @brendamcchristy6044 2 years ago I find your videos an act of love for your fellow human beings 17 Reply @melb1806 @melb1806 2 years ago This is all so true! You are a wealth of knowledge. 19 Reply @rosaleengriffin4206 @rosaleengriffin4206 1 month ago Brilliant! Thank you very much Dr Hyman. Reply @michaelfitzgerald8901 @michaelfitzgerald8901 2 years ago Thank you Dr. Hyman. You are the best! 5 Reply @user-oc3gd7ob9s @user-oc3gd7ob9s 5 months ago Very informative. This man a genius.❤ it. 1 Reply @jewlssky1094 @jewlssky1094 4 months ago Thank you for educated us. I'm going to test9 sleep apnea. And leaky guts. Reply @ByDesign333 @ByDesign333 2 years ago (edited) " There is a way which seems right unto a man, but the end thereof are the ways of death." Proverbs 14:12 💀 Such a great contribution doctor!!! 👍 5 Reply @crowdancer5 @crowdancer5 9 days ago MARK! Do not forget the heart /Brain connection. It is not jus your thoughts but The BELIVING and EMOTION of those thoughts! Reply @ArjumandBano1 @ArjumandBano1 3 months ago I did not know thats stress makes inflammation in ur body😱 thats why i have this in my Hole body and pain. I have tried so hard to loose weight for so many years, but now it makes sense… Thank u doctor 🙏🏼🙏🏼🙏🏼🌹😘 3 Reply 1 reply @AlvesterGarnett @AlvesterGarnett 9 months ago (edited) I think he is nailing it on SO MANY different levels... Wait a second ... I spoke too soon... They BOTH are nailing it. 5 Reply @julioo534 @julioo534 2 years ago I'm not a doctor, expert or something else. But a simple definition of inflamation it is when your body is expelling harmful substances or simply substances that the body itself cannot assimilate or does not recognize 7 Reply @kozen-Ronin-19 @kozen-Ronin-19 5 months ago (edited) What would you say to someone who has had a lot of antibiotics in this past year? And currently on one again because of a cat bite that bit through into the bone in my finger 😵‍💫 I absolutely hate aren't they biotics and from the virus the doctors have been throwing them at me because of recurring chest infections, I actually refused the last two times the day told me to take them, but no I have to take one because of the cat bite as I could end up losing the tip of my finger if the bone gets infected, I have also been taking probiotics for a long time and I eat a high fibre diet with intermittent fasting of 16 to 18 hours in between a meal but I still have a lot of information especially after the virus, and just before everyone asks I didn't get the jab 2 Reply @pinkoceanflower3045 @pinkoceanflower3045 2 years ago (edited) Wow! I’m very impressed with Dr. Mark Harman’s knowledge for a M.D.; I wish I could see him, but I reside in Hawaii. I need his help to heal, as I have multiple issues from severe hypertension, severe leaky gut, diverticulosis, multiple food sensitivities, severe high cholesterol, and high hs-crp. Please open up an office in Honolulu Hawaii. 9 Reply 5 replies @maryb2116 @maryb2116 3 months ago Thank you Dr,good advice . Reply @rickdacus1818 @rickdacus1818 7 months ago I have inflammation in my lacrimal gland. What is your recommendation for eliminate this inflammation? This inflammation showed up 2 weeks after I had COVID. My ANA showed positive. Do you have any recommendations? 1 Reply 1 reply @pattivandewoestyne2083 @pattivandewoestyne2083 7 days ago Thanks for all this information! Reply @Leealee-wf1iu @Leealee-wf1iu 5 months ago Hi Dr. Berg. Thank you for everything you do for us. I was diagnosed with thyroid cancer in my mid 20s, (I am 49 now). I had the entire thing removed and multiple radioactive iodine ablation. Is there anything I can do to fix this issue other than taking synthroid .100mcg for the rest of my life? Thanks! 4 Reply 4 replies @johnmcgrath6192 @johnmcgrath6192 7 months ago Great show. Poor people are under great stress and have to eat a lot of starches because they are cheap . Plus, like most of use, poor people probably eat a lot of sugar. Plus many poor people are plagued by prejudice, sometimes severe. 7 Reply 3 replies @vasantidevjee4318 @vasantidevjee4318 3 months ago I have inflammation in my spine, how do I deal with it. Lots of burning pains in the lower back and between the shoulders 🙏🔥please help. 2 Reply @81redddd @81redddd 2 years ago Can you do a video on adrenal fatigue? I’ve tried so many supplements and nothing is working and now my health is declining and I can barely function 8 Reply 12 replies @angel21991 @angel21991 1 year ago Interesting conversation , but I think the bigger picture that seems to be overlooked is that industry in every era was optimized for profits and not for human well-being and sustainablity.We can be euphemistic about it, but it is the overarching truth. Given the scape monopolies that control healthcare,media , data and food industries are systems will have a hard time to break out of realigning and reflecting priorities steeped in well-being. 2 Reply @latinaprincess5901 @latinaprincess5901 2 months ago Thank you ❤ love listening to you Reply @nadiafaucher7060 @nadiafaucher7060 1 month ago I know it’s been a year since this post but I will try asking that question in case. I have been diagnosed with epilepsy for about 30 years now, I take meds that control it. The question is, out of all mental heath at He mentioned doesn’t include epilepsy. Could epilepsy be considered a mental health disease or brain disorder . Is it possible that eating a Whole Foods plant based diet could help? I don’t know what long term of that medicine could cause any other health disorder. I am 53 Reply @raghuarmani8341 @raghuarmani8341 2 years ago Thanks. Very informative Reply @rockonmadonna @rockonmadonna 4 months ago A lot of listening… and I still never heard, what are the four newly studied markers of inflammation and aging, please? You mentioned them several times but never enumerated them. We all know C reactive protein, sedimentation rate, Vit D, etc. What most doctors never run is the WUSTL autoantibody panel for small fiber neuropathies. Traditionally, all the research has been on the central nervous system and large fibers that control motion/strength (and still desperately underfunded -We are in the Dark Ages of neurology.) but not the small fibers, which control everything else. Americans especially focus very superficially, skin deep. The major players are the nervous system, the gut, and basic sleep, nutrition, diet, and unfortunately for those most vulnerable in this digital age, relationships. Everything else should fall into line unless it’s really already whack and you have to go down the road of IVIg or MABs Ike plasmapheresis, chemo (to be avoided as the mainstay) etc. Reply @jen_81 @jen_81 2 years ago Dear Dr, pls consider putting Time stamps🙏 12 Reply @alchemybyangela @alchemybyangela 7 months ago Since stopping HRT using Prempro for menopause I feel a lot better in many ways. 2 Reply 1 reply @Mariafontana @Mariafontana 2 years ago Great information Doc 1 Reply @suzannerodriguez1869 @suzannerodriguez1869 1 year ago I had no idea that so many things cause inflammation 😮 3 Reply @rosemariepinlac9323 @rosemariepinlac9323 2 years ago Hi Dr. Hyman, I always watch your channel and I also bought your book Eat Fat Get Thin. thank you for your professional advice. Can you recommend a functional med doctor near NJ or NY? 2 Reply @poosakum @poosakum 7 months ago This Inflammation Is very shady area Thanks for giving valuable information. Reply @dr.debbiewilliams4263 @dr.debbiewilliams4263 3 months ago (edited) Despite what it says at Walmart, I can barely pinch an inch of fat. There's pain, without the heat in my feet. Even smaller shoes fit, and I only weigh a little over 100 pounds at 5'4". Reply @bushaak5282 @bushaak5282 7 months ago Hello sir. I had neck and shoulders pain for the last year.investigations revealed that I had post corona chronic bi lateral brachial plexus inflammation and many cervical Tarlov cysts. Are Tarlov cysts due to inflammation? Reply 1 reply @SurenderKVats @SurenderKVats 3 months ago Great information! Thanks Reply @linh8997 @linh8997 2 years ago Can you tell us how you eliminated heavy-metal poisoning? (I have suffered from aluminum poisoning four decades!) 6 Reply 3 replies @roblovegreen @roblovegreen 1 month ago Inflammation is the body’s natural process. It means injury is present needing healing or infection is present. You must find the root cause. Reply @mountaincat8 @mountaincat8 2 years ago Can anybody summarize this? Thanks a million!! 15 Reply 9 replies @jaishankarravindran2242 @jaishankarravindran2242 9 months ago Preserving the status quo is enigmatic . Reply @maritzaperez269 @maritzaperez269 1 year ago Thank you Dr your informations are very helpful, bendiciones Reply @tiffhamill567 @tiffhamill567 8 months ago (edited) I have to give God credit for erasing my inflammation .. I prayed and read Bible and asked for wisdom. He has helped me health wise, financially, getting off pharmaceuticals carefully. My dr is speechless and I love it! Side note: key word to antibiotic was fetal tissue — I’ve researched the opposition to fetuses.. we are being taught it’s just cells. Think for yourselves.. we cannot make a decision to be God-like by stopping a possible live human. Unless harmful cases 6 Reply @barbnativenewyorker @barbnativenewyorker 8 months ago (edited) Yes I have gut issues and so many things have attacked my body that should not be and am fine tuning diet even further. Wish you were in NY I cannot get the proper medical assistance to heal my gut. 1 Reply @jmt7472 @jmt7472 2 years ago As an FYI regarding testing, most, if not all of the testing mentioned is not covered on HMO Medicare. And, never is any alternative, functional medicine covered. 5 Reply @elinashome-economics @elinashome-economics 3 months ago (edited) Do you have Home Economics as a compulsory subject for secondary school students? There are several studies that show the importance of practical nutritional education: If you learn children about healthy nutrition and how to make tasty food from scratch, they are more motivated to make their own food, make good lunches to take with them to studies, and generally, live a more healthy lifestyle. I have worked as a HE teacher for over a decade in both Finland and Sweden and working with a research project concerning education in nutrition, health, sustainability and private economy. 1 Reply 2 replies @AngieLovesItaly007 @AngieLovesItaly007 4 months ago I fast every Sunday and most Mondays too. 2 Reply @jillfield3102 @jillfield3102 2 years ago Great as usual 👍💖🇬🇧 3 Reply @onedirection3510 @onedirection3510 2 years ago So surprised he never mentions the inflammation of the prostate which is apparently a massive problem for millions of men. 5 Reply 1 reply @blessme-ng9gu @blessme-ng9gu 2 months ago Boil decoction 6- 10min of any leaves, herbz,roots barks, stems, has one effect ... where as raw grated turmeric peppercorn, ginger with lemon salt salad dresing has another. 1 Reply @cindyhesley6450 @cindyhesley6450 2 months ago Brilliant man, he should be in our government as the leader in our health system and deserves a place in our country leading the way with NO debt to big pharma. Our congress, senators, and president have all gained millions from passing laws for self gain to BIG PHARMA! 1 Reply 1 reply @maryabraham9182 @maryabraham9182 2 years ago When we listen to Dr. Hyman we feel so happy we feel he’s the only one who’s going to help us ,and I was one of them, I did some research and see what other people were saying, most of them they were so disappointed he didn’t help them ..and it cause thousands and thousands of dollars !! so I don’t wanna go see him ...if he’s that good why he doesn’t be reasonable with His prices so he can help as much as people as he can????? but it’s all about the money!! He doesn’t care about his pension they are just a number , that’s sad world we live in today😔😔😔 2 Reply 4 replies @sammurphy4122 @sammurphy4122 4 months ago What is the supplement that contains glutathione that can be bought over the counter? Reply @wickerman5577 @wickerman5577 3 months ago I have to say, I have friends whose diet was excellent but still had, Non Hodgkins disease and cancer, stress and lonlinesss seems to be the only constant. 1 Reply @rf7867 @rf7867 1 year ago Great Interview. Which magnesium supplement do you recommend? I suffer from constant headaches. 2 Reply 3 replies @10forthebigguy @10forthebigguy 5 months ago This guy is more of a social scientist than a biological scientist!! Reply @shaunblock9392 @shaunblock9392 3 months ago Thanks for the info so much better when you know!!!!!! Reply @philomenabrabazonobroin5236 @philomenabrabazonobroin5236 6 months ago The reason some people bounce rather than sink is they have Jesus in their lives. I have been through so many traumas and if I were to look at them I would sink. Instead I look at Jesus and know I am not alone, I then have strength to carry on and a reason for my sufferings …..to join them to Jesus’s sufferings and offer them for the glory of God and the salvation of souls. He then heals me and each trauma is a lesson. The reason I add this is that food is Gods pharmacy, but it’s not the whole story❤ You need faith in the one true God as well !!! 10 Reply 1 reply @lindasmyth2056 @lindasmyth2056 5 months ago Do you have any comments as to the effect of fasting and PMR. Reply @gracefriedman8695 @gracefriedman8695 1 year ago Scripture says be transformed by the renewing of the mind. Reading scripture and trusting God who created us 26 Reply @jeanmarie4507 @jeanmarie4507 2 years ago Great questions, interviewer ! 1 Reply @FollowScripture @FollowScripture 1 year ago (edited) Dr. What probiotics should i take Rebuild the gut? TY Reply @gracefriedman8695 @gracefriedman8695 7 months ago The missing link to taking thoughts captive is renewing our minds through the word of God. God has been taken out. Thus stress and eating toxic “foods” 4 Reply @JosetteBadger @JosetteBadger 2 years ago Ok ok ok but can we all acknowledge that this man is in his 60’s and I thought he was a healthy 40 something year old!?! 21 Reply 3 replies @pastorDbow @pastorDbow 1 year ago I agree lower inflamation is good, but it will not bring world peace or utopia. It is little over the top. Still, I appreciate encouraging research and focus on brain science particularly. Also, I see systemic lack of sound critical thinking and virtue drive dysfunction in society, which are a root cause of stress and dysfunction. 1 Reply 1 reply @nicoled.4472 @nicoled.4472 2 years ago NAC is helping covid patients recover so there is a shortage for the slow release version. 1 Reply @jessicaramos2804 @jessicaramos2804 1 month ago Wow great info 👍 Reply @michaelmelamed9103 @michaelmelamed9103 3 months ago It’s all making sense because all political upheavals and wars have taken place over the issue of being deprived of food or rights 1 Reply @glizzzb0y595 @glizzzb0y595 1 month ago amazing video thank you so much Reply @cheryl5228 @cheryl5228 1 month ago The doctor told me in all the years he has seeing patients, I have the cleanest gut he has ever seen. I have chronic inflammation and have been working at decreasing it with no success. I don't eat sugar, I have a healthy gut, and try to control stress, so why all the inflammation? 1 Reply 1 reply @Mauitaoist @Mauitaoist 1 day ago (edited) Almost all of the inflammation in the human body comes from plant food. I started eating a proper human diet and I stopped eating all plants 2 years ago and I've never felt better I'm never going back Reply @lauranolan4744 @lauranolan4744 6 months ago Brilliant….. The cure is in Your Kitchen ❤ 2 Reply @sarahtheorme @sarahtheorme 1 month ago The naturopaths have kept this knowledge alive. 1 Reply 1 reply @AngieLovesItaly007 @AngieLovesItaly007 4 months ago Please don’t drag this out. We know what inflammation is. 4 Reply @chezzerk @chezzerk 2 months ago (edited) Interesting been listing to morley robins about poorly understood copper Plays in the gut and role of Ceruloplasmin in treating schizophirena Reply @seattleareatom @seattleareatom 2 years ago My theory I call ANDS acquired nutritional deficiency syndrome will be the downfall of humanity unless we kill ourselves off in some other fashion. ANDS in my book = the next extinction. 4 Reply 1 reply @ByDesign333 @ByDesign333 2 years ago vicious cycle of inflammation...YES! Reply @myrtlehaas5959 @myrtlehaas5959 5 months ago What causes blood vessels to pop in your eye? Reply 2 replies @Bobbi517 @Bobbi517 4 months ago (edited) I have been diagnosed with Autoimmune Hepatitis. I just end a three day food fast. I drank coffee, tea and water. Now I just feel lousy. I still feel as if I have inflammation and it’s been 4 days since breaking my fast. Can anyone help?I am 72 years old. Reply @elizabethosomo9999 @elizabethosomo9999 4 months ago Everything originates and returns to God. If people should train themselves to reading the Bible; starting from reading one chapter a day, it’ll help reduce the stress and increase peace in people’s minds. 2 Reply @rhondachristensen8619 @rhondachristensen8619 6 months ago Our entire, American diet, finding out, is " inflammatory " if 4th of July holiday comes along and we attend 2 BBQs and a pool party, chances are we are eating hot dogs, hamburgers, pototo chips, soda...all, inflammatory foods...😢😢Americans gathering around the BBQ grill, chances are, is eating red meat; which is a contributory factor... Reply @aprilpitzer6404 @aprilpitzer6404 2 years ago How did you deal with your house mold issue? 3 Reply @bonniec3397 @bonniec3397 2 months ago I remember my kids would pick out their box of cereal by what toy was inside, not because it was good for you. Reply @robertrosell7103 @robertrosell7103 1 year ago This guy is good 3 Reply @naima8392 @naima8392 2 years ago He gave an example of a woman whose daughter was in Israel, saying she feared for her daughter's safety. I would like him to mention the trauma that Palestinians go through on a daily basis under the occupation. Israel is an An Apartheid state that is not only occupying Palestine but destroying and demolishing their houses for no other reason than letting settlers take the land by force. 23 Reply 3 replies @wendym2544 @wendym2544 2 months ago What food has starch and what foods have resistance starches? TY! Reply 1 reply @conniebuenasvlog9789 @conniebuenasvlog9789 10 months ago Thanks for the information… Reply @rp011051 @rp011051 6 days ago Good info. Feedback...food comp are based on capitalism, profit is good regardless of harm as long as legal Reply @CordulaPrice @CordulaPrice 1 year ago Thank you I just subscribed 😊👍🏻 1 Reply @Santu2409 @Santu2409 2 years ago I would never use any kind of electro magnetical signals during my preciuos sleep. Ones bedroom should be totally free from any kind of "dirty electricity" and other EMF:s. And keep your bedroom cool... 5 Reply 1 reply @justinlugo1661 @justinlugo1661 2 years ago Great podcast. Also let's go Brandon 9 Reply 1 reply @nadyhenry9986 @nadyhenry9986 8 months ago Hello Dr, I am suffering from infertility. My Dr told me that my tubes are blocked. Can you help me please. 😢 Reply @rajeshtanwar2445 @rajeshtanwar2445 3 weeks ago Really enlightening discussion by Dr.Mark Hyman going to the root causes of various diseases of serious nature. Objective and scientific knowledge..❤🎉❤🎉 Reply @juliantreidiii @juliantreidiii 9 months ago You train your brain with meditation. 1 Reply @gingermiller1087 @gingermiller1087 2 weeks ago Why do you constantly inappropriately laugh? It really takes away from what you are saying and is awkward for those you are talking to. I mean, really, what does a person do when they are talking to someone about an important serious topic and the person talking keeps laughing unexpectantly -- you're uncomfortable not feeling certain how to respond. Do you start laughing also, even though there is nothing funny about what he/she said? Do you just stare at them when they're laughing all alone? Or, do you ask the person "what are you laughing about?", which is what you want to know but it just makes the situation even more awkard. Please STOP IT. Reply @liepa7768 @liepa7768 7 months ago Good questions from the interviewer but the other guy is probably the leftist 😂. He didn't answer a single question, began to defend food industries, went to conspiracy theories, made fun of them and then I lost my oatience 😂 1 Reply @dorisallen3440 @dorisallen3440 7 months ago I have weeping blisters for 8 weeks now. It keeps me awake and it's a wet pain during day and night. Dr put me on 2 rds of antibiotics and Prednisone and ibuprofen. Help please Reply @croys8608 @croys8608 5 months ago No excuses! Reply @bradtozier6776 @bradtozier6776 6 months ago Best treatment of all? Eat a non-inflammatory diet (the animal products that are most suitable for you). That's how I earned an hs-CRP score of .3, revealing zero inflammation anywhere in my body. At age 64. 1 Reply @user-th8rj4ur3s @user-th8rj4ur3s 4 months ago (edited) I'm a little confused, so if we have a loss or a breakup or can't pay bills. Which causes me to be depressed. It's from inflammation 😮 idk. Our foods are being depleted of nutrients from the natural process of growing they strip the dead plants instead of the plant dieing and sending the nutrients back down into the soil. The heavy medals in the water from meds and forever chemicals from plastics. Toxins and mold in the air. Round up sprayed on crops 😢 chemicals in our daily used products it's a whole process to escape everything. 1 Reply 1 reply @AlejandroRamirez-ly3fj @AlejandroRamirez-ly3fj 2 years ago Intermittent fasting and clean diet will fix most of health problems 21 Reply 6 replies @starfishw7138 @starfishw7138 2 years ago I've read not to take NAC with heart problems. What do you say? 3 Reply @yojanasingh7057 @yojanasingh7057 2 years ago Please advice where to get the particulars gut microbes . I hear so much from you but no guidance from where to buy 5 Reply @kimsimon4641 @kimsimon4641 2 months ago For someone that has sjrogrens disease, doesn’t show inflammation in body . Is there another blood test that works Reply @joshitaghosh4188 @joshitaghosh4188 2 years ago I am suffering from reccurant Uveitis in left eye.I am HLAB 27 positive and pains in various hoints especially buttocks since many years. If you can plz discuss and give some information. 1 Reply 10 replies @lindaphelps7376 @lindaphelps7376 2 months ago How do you treat muscular dystrophy Reply @mikimiki6202 @mikimiki6202 8 months ago I had to beg several gynos to let me get off the pill after more than 10 yrs. It destroyed my health and I developed breast cancer. Lost trust 2 Reply @josephprince4535 @josephprince4535 5 months ago Thank you.. nice information about information..cornivore diet may helps reduce inflammation Reply @NaWesolanute @NaWesolanute 2 years ago (edited) Gut inflammation . Feel burning,hot ,poor sleep. Fasting help me a lot. Keto diet ,,organic,, this is my medicine. Propolis help me a lot with flexeseesd bio oil 4 Reply @adorableparakeets3608 @adorableparakeets3608 2 years ago It will be good to have videos shorter, all Videos do not have to be hour plus long…. 5 Reply @SANTTUBHAI @SANTTUBHAI 1 year ago Thanks 👍🏼🙏 Reply @caturtalk44 @caturtalk44 1 month ago Have you heard about grounding which can help handle inflammation. 1 Reply @joanwilson4491 @joanwilson4491 2 months ago As Mark stated early on here, the average standard of care doctor is 30 to 40 years behind functional medicine and the best research out there. Governments are bought by the highest bidder, the multi billion dollar industries (coca cola is richer then 22 different countriesand saw a 10 billion dollar revenue from food stamp dollars alone last year)..all these nasty entities are impossible to change. Much as I love to hate on these monsters...change will only come from the people as always. As with every other aspect in a life well lived...personal responsibility is the biggest key. Do your own research and make sure you know who payed for said research. Reply @chuntathecat4222 @chuntathecat4222 8 months ago Mark is best 🫀🫶🥝🥬🥦🍠🥒🍆🍅🍑🫐🍐🍌🥑🍗🍤🍣🥜🍵🫘☕️🍘🥟🦪🍛🍲🍱🥘🌮🥗🥙🥩🍳🥞🧄🫒🥕🥙🫑🥥🍒🍍🍓🍇🍉🍋🍊 1 Reply @pawank1515 @pawank1515 6 months ago Are there any tests you can do to check inflammation? 2 Reply 2 replies @Ajhc73 @Ajhc73 2 months ago Just got over uveitis I have autoimmune disease I’m celebrating with a Malibu and pineapple .. until the next time my sights threatened il say CHEERS 🥂 Reply @effiebillias8602 @effiebillias8602 1 year ago 9.30 from stress my whole body is diseased 2 Reply 1 reply @Asianrawveg @Asianrawveg 2 years ago Hi I'm a fibromyalgia patient. Can you provide your clinic number I would like to make an appointment? Reply @folukeakinyemi2024 @folukeakinyemi2024 1 month ago Doctor well done, please is possible to treat rheumatoid arthritis naturally? I am tired of taking drugs. It causing me to lose my hair and side effects are terrible! Reply 2 replies @georgeshepherd3381 @georgeshepherd3381 2 months ago How about being interrupted by an ad while watching a good video like this? Reply @VEE02010 @VEE02010 4 months ago Women's Hot Flashes: Frustration and Bad thoughts! I've experienced it. Reply @user-th8rj4ur3s @user-th8rj4ur3s 4 months ago Plus the hidden ingredients in our foods 😅 Reply @kristingoettlicher3503 @kristingoettlicher3503 3 months ago I know bc pills reduce vitamins, but I didn't hear about raising crp. Reply @sheilahollinshed933 @sheilahollinshed933 5 months ago Does it come from Fleas in the Body Reply @gregroth4696 @gregroth4696 2 months ago Can you tell us in 5 minutes? What 3 things? C’mon! Give value for our time. Reply @lissarx2459 @lissarx2459 6 months ago Can functional medicine help allergies? Mine are not food, but seasonal, and they’re really bad. 1 Reply 1 reply @2-worlds-on-earth @2-worlds-on-earth 1 month ago Agreed…..the current America society is toxic Sad Reply 1 reply @thomashendrickson9651 @thomashendrickson9651 4 months ago How do you treat for heavy metals? Reply @sandrad250 @sandrad250 2 years ago My first Pfizer vaccine caused inflammation. 19 Reply 5 replies @amadeusJ6 @amadeusJ6 3 months ago Did he say.. c-section. My belly has never been the same after this 😮 Reply @lindachancio6819 @lindachancio6819 3 months ago Mark doctor Mark thing you did forever except for the not the mercury but I am just suffered with a lot of stuff and I my mother was a moderation person Sheila for 100 to 101. I don’t wanna lose 101 not in the society, but in any case I do a Lotta good things and I played tennis for 30 years and now on hard court so now my leg is saying you can’t do that anymore and whatever but you are the bomb you and when you enter he Bobby Kennedy, I volunteered to be on his exam whatever his campaign. Yes he is great too smart for the American people I think that’s the only problem he’s just too smart to stand up but anyway, the other thing I was gonna say about the micro whatever in the garden stuff I just got out of the hospital with the right one pneumonia and I didn’t haven’t felt well for two months, but I’ve been under stress unbelievably with my family. My son passed away. My husband passed away. I lost my her not lost my house. I sold my house. I’ve had a lot of loss and I’ll tell you that stress will kill you cause I know my immune system is down but in any case I’m getting better and then I’ve had my diagnosis from the hospital and I had serious sepsis. What’s up without septic shock? No, I wasn’t going to go to the emergency room and I’m glad I did I probably wouldn’t be texting you this or commenting on this but anyway keep up the good work I wish you were my doctor where do you live cause I can move anywhere I’ve moved 1 million places lived in million by cases so anyway just keep up the good work and stay safe😮🎉 Reply @gerrihowitt3965 @gerrihowitt3965 6 months ago I have Rr.A Arthritis and have been on Enbrel injection for awhile, how do I make the change. I am on a probiotic and follow Plant base diet. I am 78 years old , do not smoke or drink alcohlal Reply 1 reply @Henkvanpeer @Henkvanpeer 3 months ago Mr hyman really likes to talk… Reply 1 reply @_____J______ @_____J______ 2 years ago This video should get more shoutout 3 Reply @yojanasingh7057 @yojanasingh7057 2 years ago Please where to get the tests done 1 Reply @bh613 @bh613 2 years ago Love ya dr Reply @jessicaramos2804 @jessicaramos2804 1 month ago ❤❤❤❤ Reply @fannyduchen4688 @fannyduchen4688 2 months ago Where can I find the doctor ? Reply @owenfreiburger @owenfreiburger 7 months ago Brilliant Reply @mikenowacki9729 @mikenowacki9729 7 months ago (edited) So I had Asthma since I was 5 how would that be because of stress Reply @ceceliahayes6059 @ceceliahayes6059 7 months ago WHAT ARE WE DOING TO CAUSE INFLATION... SUGAR BABY .... SUGAR. 2 Reply @robertstrong729 @robertstrong729 4 months ago Wait is even a baby aspirin bad? I take one a day. Reply @joefarhat7731 @joefarhat7731 2 years ago I was hoping that the actual link would have been put into the notes; Referring to the pomegranate concentrate, cranberry and green tea mixture!? Reply @kristasliwinski @kristasliwinski 6 months ago So this guy is a doctor??? What is this man's name and where is he located? Does he have an office??? Can I make an appointment to see him??? I have Celiac's disease and 11 different food allergies, I have not eaten out since 2015 and I have eliminated basically everything from my diet, I can literally only eat a few different foods and any time I try and reintroduce any food, even fruits my whole body is affected every morning I feel like I have been hit by a bus and so im thinking it must be inflammation, but I dont know. I only make my own foods I never eat out and I never eat processed foods, I can only eat beef. I do have narrowing of the bile duct which my doctor told me I was born with. I'm 35 years old and I definitely have helped myself tremendously since 2015 but I still need help!!! No doctors around here where I live can help me, they look at me and tell me I look fine. Looking fine and feeling fine r two different things. I haven't gotten help besides the food allergy blood test which I cut out all foods im allergic to have I did feel 100% better and then I tried to introduce fruits, vegetables, only foods that r natural, around here where I live its organic, non gmo I only eat organic and if it doesn't say organic I make sure it says non gmo and if it's not organic or non gmo I don't eat it. I never eat processed foods and I do not wear wake up and im 52 and 90 pounds I don't have much energy bcuz I can't eat much and my whole body is super sore feeling, all my muscles and joints r sore, my legs and back r the worst, I know stress is a big big issue for my body and my mind is the best it has ever been in 35 years so I know I'm helping myself but I know there is more I need something I'm missing.. I have not tried any herbs yet so idk maybe I need to try herbs. I have done saunas I need to go again and my body tells my mind what I need to eat and what I need to do, for example before even watching this video my mind has been telling me to look up and teach myself the steps I need to take to do cold plunges. I will have to work on that now. I can not live like this to much longer bcuz my everyday life is affected and my work and my family and relationships and everything in my life is affected bcuz im sick and stuck and misunderstood and noone in my family understands. I know I have immune system issues. I know it's my gut. I know I need help, I do not know where to turn but I do have a father that can help me financially if I need to see an expensive doctor, that can actually help me save my life, that is most likely what I need!! Idk why I have issues with every food I try to reintroduce back into my diet. I have issues with fats and digestion but i think i know why now bcuz Celiac's and narrowing of the bile duct both casued digestion issues and narrowing of bile duct i cant digest fats. I used to have stabbing pains in my stomach which once i found out other foods i was allergic to and then i stopped eating them i was 100% better and inflammation was gone and no more pain in my stomach, gut, colon, im not exactly sure i just know i had stabbing pain on left side i believe above my ovary on left side, maybe it was my colon or maybe it was my small Intestine or large Intestine idk im not a doctor i dont know exactly where organs and things r, i can only look at pictures. I only eat certain brands of certain foods, I only eat 100% grass fed grass finished beef, really only filet mignon steak and that is the only meat, other protein is cheese aged 6 months(organic) and pistachios nuts. I have tried black beans and I can't eat black beans, I can not eat salmon. I have issues with toxins and chemicals and processed foods and stress but I know how to control my stress so I do not get to stressed. I have learned to control my emotions and never rush around! I have changed my shampoo and soap to the same one bar of soap that comes in a box. Organic oil with 2 ingredients. And never any make up or botox or plastic surgery or anything that's not natural or real. Never any food or anything with more then 2 ingredients. Never any medications, no synthetic, man made stuff. I try n do all natural,organic everything. Which obviously is more expensive around here where I live. I do believe my environment has something to do with my issues. I would love to move I do need to feel better so I can work more so I can save money so I can move. I do believe in myself, I'm very strong minded and I will not give up and im very empathetic and sympathetic and I put myself in other people's shoes and I just hope there is someone out there that can help me help myself. I will and have been helping myself and I can't give up, that's not an option for me. I have a mother and father and 3 brothers so I can not end my life. I want to live and I believe I can help millions of people if I can figure out what's going on with me and help myself naturally I think I could help other people that WANT and need HELP. If u r actually will to take suggestions to help urself, like I am. But I need a natural doctor or a doctor that can help me with my immune system or know the root cause of these issues and help me help myself to fix whatever issue I have going on!!! I need the help and I do not know where else to turn. Thanks, hopefully someone out there can help me. I ate a mango for the first time in a few years and I got hives and itchy and sore muscles so maybe I'm actually allergic to mango, idk maybe I ate to much in a short period of time, idk. I am still itchy but no hives anymore. I do know ever since then my body has been super sore again after cutting out the other foods im allergic to. I'm allergic to, wheat, barely, oats, corn, soy, peanuts, yeast, potatoes, rice, apples and oranges. I was sleeping about 9 to 10 hours every night which now I sleep maybe 6/7 hours. But I can't eat dairy for some reason besides organic cheese aged 6 months. I can only eat 100% grass fed grass finished filet mignon and small amount of 90/10 ground beef, organic avocado every morning, lettuce and cheese and pistachio nuts every night for dinner. So I eat avocado for breakfast and then lettuce, cheese, pistachio nuts for dinner and filet mignon about 2 days out of the week, for some reason I can only eat small amounts/portions at a time and I only drink Fiji water and I use one green tea tea bag every morning and that is it. I do try to eat kiwi at night and I do sometimes eat pasta that has one ingredient which is cassava flour, organic Jovial brand with one organic tomato I blend up and I add organic garlic and organic salt and pepper and that is literally all I can eat, whenever I try to add something into my diet like a fruit or a vegetable or I try to eat some kind of meat, like lamb, or pork, or chicken I have major issues!! I do once and a while eat a banana and sometimes I eat a few bites of kale in my salad. Idk maybe I should try a herb like Ashwagonda root, turmeric, and or yucca(cassava root) idk I felt before like I needed and maybe I still do need a steroid, I dont know but I'm worried i would have a reaction so I googled natural steroid and yucca root(cassava root) came up so idk maybe thats what I need to try and eat next, I don't know tho. I guess if I can get this doctors name, and office # or something so i can try to make an appointment with him. Idk what else to do!! Reply @christopherrussell4128 @christopherrussell4128 2 years ago Imagine how many doctors I’ve seen in 40 years, not one has said the term “microbiome”. That’s the problem. Here we have a real doctor ladies and gentlemen. I will fly out to wherever your office is to have an appointment. Where are you located? Telemedicine? 3 Reply @giod3643 @giod3643 2 months ago But aren’t we as humans living longer… so with increased inflammation doesn’t correlate with the increase lifespan?? Reply 1 reply @georgesmith8113 @georgesmith8113 2 years ago 👍👍👊 Reply @marzymarrz5172 @marzymarrz5172 5 months ago Maybe diet explains why there is so much random anger on the road. Reply @artdeltoro @artdeltoro 7 months ago So, the so the fourth is Sedentary Lifestyle. 1. Gut health issues - an unhealthy microbiome 2. Process food, sugar, starch. Having too much belly fat. 3. Chronic stress 4. Sedentary Lifestyle. 1 Reply @davidtsw @davidtsw 2 months ago Ok but the part about sugar being the evil is so wrong. It's fat that causes diabetes, hearts disease and more, not sugar. Fat and sugar is the worst combo so pretty much what most people eat. The science is out there people. The problem is we never really went kow fat as it was recommended years ago. All the cheese and other dairy plus lots of protein and other fats like cooking oils and so on, we increased our fat consumption. Reply @andreanunez1258 @andreanunez1258 2 years ago Need help for my 100% DV Vietnam vet father. inflammation is so bad he has diabetes, major heart attack and stroke, he is in a lot of pain all the time. we don't have funds to do all these test. VA is no help with functional health. 3 Reply 1 reply @misfyresalot @misfyresalot 2 years ago Does Dr..Hyman take new patients? Reply @christinechurch8181 @christinechurch8181 1 month ago Thank you Reply @marthachaves9878 @marthachaves9878 7 months ago What food is anti-inflammatory for arthritis I have pain in my hands fingers thank you 1 Reply 1 reply @annefitz7346 @annefitz7346 1 month ago Please go speak to Congress about food additives processing etc. it’s costing billions as most of my patients have metabolic syndrome! I’m fighting it & doing what I think is best & I’m still struggling with diet etc. I’m 71 but my parents lived into their 90s. We DESERVE BETTER. Bet they can find other ways to help farmers ! Reply @rossvalentine8211 @rossvalentine8211 1 month ago Come to spacehey Mark, no algorithms!!! back to how social media should be... Reply @haroldhart2688 @haroldhart2688 10 days ago I HAVE HIGH PITCHED TINNITUS ESPECIALLY WHEN I EAT = WHAT IS THE CAUSE.????????? HELP !! Reply @AfroCuban4life @AfroCuban4life 4 months ago Clindamycin sucks! It messed up my stomach. Protest if they prescribe that to you! Reply @renukachauhan7819 @renukachauhan7819 1 year ago Thanks. Reply @kony8449 @kony8449 3 months ago Advertising targeted at children should be strictly prohibited. Reply @jeanmarie4507 @jeanmarie4507 2 years ago How do I schedule a visit to your clinic? My Christmas present! 1 Reply 1 reply @Lannie74 @Lannie74 2 months ago This guy that Dr. Hyman is talking to sounds exactly like Dr. Sanjay Gupta on CNN and even looks like him. I’m thinking it’s Dr. Gupta s clone no joke Reply @tonysantos-ocampo3849 @tonysantos-ocampo3849 4 days ago 😊 Reply @armandofretto9917 @armandofretto9917 4 months ago (edited) You say GOS reduce gas : i put it to the test : i’m getting gas at all time ;as only when i eat broccoli what part of the information did i missed? Reply @christasailer882 @christasailer882 1 month ago Trank you for your valuable Information, though i Miss you mentioning the mrna vaccination. Reply @lloydTom911 @lloydTom911 2 months ago Is ground meat high inflammatory Reply @claudetterichards2063 @claudetterichards2063 4 months ago Do you have any advise how to treat receding gum.. 1 Reply @glendaguilott3765 @glendaguilott3765 1 year ago We all need Yahusha !!! 3 Reply @AmethystWoman @AmethystWoman 1 month ago CRPS. Cytokine is us. Then add covid and long covid. How to do an antiinflammatory diet, low fixed income and feel sated. I need protein. And red meat probably twice a week. Need to do gluten free which might be sympatico. Live alone, disabled, how to do this? Feels really hard. Reply 2 replies @shivaasia @shivaasia 7 months ago Mind and brain it’s not the same Reply @sharnie528 @sharnie528 3 months ago ❤❤❤❤❤❤ Reply @MillieToro @MillieToro 2 years ago (edited) How do you spell the test company? Ediphis? and where are the links to the drink he talked about lol not listed. 1 Reply @booswalia @booswalia 2 months ago Why not just assume you have inflammation and eat a preventative diet. 1 Reply 1 reply @LAppleDumpling @LAppleDumpling 2 years ago 🤔🤔🤔 did Oreos start off with "good intentions" ? Ummm 🙄no just like C r isco was no oil mistake! I just found out in certain countries you bring in corn oil you'll be fine arrested ran up the flagpole but over here in America they pushed corn oil like crazy. 3 Reply 2 replies @charleneparson7858 @charleneparson7858 2 months ago What are seasonal fruits Reply @Sconzette @Sconzette 1 year ago I like Dr Hyman , he's full of good information but why the hell does he always have to laugh , that's so annoying!! 1 Reply @leadimentoobrien1221 @leadimentoobrien1221 2 years ago Wonder if we should take a baby aspirin? 1 Reply 1 reply @cefcat5733 @cefcat5733 6 months ago A pound of sugar per day? 😢 Reply @thisoldboat7393 @thisoldboat7393 3 months ago (edited) Why does it take an hour to explain something like this?? 1 Reply 1 reply @Ken-cf9bc @Ken-cf9bc 2 years ago Just one question you promote eating completely healthy and I agree then why do you sell so many supplements? 1 Reply 1 reply @gregorylewis9442 @gregorylewis9442 9 months ago Too much Starch and Sugar? Look at all the processed foods in AMERICA!🤢 2 Reply @christinemeyer7163 @christinemeyer7163 1 month ago People have too much time and money, they are bored, so they sit, watch movies ..and eat Reply @kv1039 @kv1039 1 year ago can you eat brown rice ? Reply @shawnahipple4818 @shawnahipple4818 2 years ago Read the labels! 1 Reply @sumonkirwin7005 @sumonkirwin7005 2 years ago Don’t eat anything that has labeled at all . 3 Reply 2 replies @claudetterichards2063 @claudetterichards2063 5 months ago Mucus is inflammation? Reply @rosemacaskie @rosemacaskie 2 years ago You look so wel Mark Hyman, better than I remember you looking in other interveiws. YOur eyes are genteler an more serious. Maybe I make it up. 2 Reply @cynthiacrespin2061 @cynthiacrespin2061 1 year ago Mark Hyman doesn't look healthy , the dark circles under eyes are worrisome 1 Reply @charlienemeth1342 @charlienemeth1342 4 days ago CAN HE SWALLOW HIS SALIVA???!🤷‍♂️🤷‍♂️🤷‍♂️🙄 Reply @jaywellington6504 @jaywellington6504 7 months ago pssst......they didn't want to "take over the Capitol".....none were armed who busted into the building. How do you "take over" a place with no weapons?? You don't. It's obvious they were moving their protest into the building were law is made to get noticed. It is OBVIOUS...I don't approve of their actions that day at all yet I know that much. 4 Reply 1 reply @annefitz7346 @annefitz7346 1 month ago What the heck caused your mercury poisoning??? Thermometers? E chess seafood? Reply @rosemacaskie @rosemacaskie 2 years ago My mother in law thought that advertisments made people buy the products, and did buy childrens presents she saw on the tele , my mother told us not to take any notice of them and did not herself buy things from hte television and I never wanted to buy anything I saw on tele.I buy what she bought. Reply @super0chick @super0chick 1 month ago So, what actually can we eat. Even fruits and veggies are probably from GMO grown, pesticides, and grown from soils that are nutrient deficient. So depressing. Reply @beverlyhoward3512 @beverlyhoward3512 1 month ago Everyone doesn’t have ur knowledge, go into more in depth would be helpful Reply @bmelvin1234 @bmelvin1234 2 years ago Take probiotics 2 Reply @jaishankarravindran2242 @jaishankarravindran2242 9 months ago Standup desk dosen't rectify sleep apnea. Reply @2kkto2 @2kkto2 1 month ago 5 minutes into your video and a 38 minute commercial??? Reply @rp011051 @rp011051 6 days ago Also, doc keeps claiming g I got rid of xxx of patient. Very arrogant ,no credit to paying customer or patient Reply @goodgreenenergy @goodgreenenergy 1 month ago Did you just say January 6th riot was intended to make the world a better place? Reply @MinMin-uy5pl @MinMin-uy5pl 8 months ago Why oh, why no one is lobying in the congress to pass better control over food, especially in schools and hospitals. 1 Reply @joecool3332 @joecool3332 2 months ago If you click on a gut health video, you get every health related supplement propagandized to the public for profit. Reply @christinemeyer7163 @christinemeyer7163 1 month ago Then very soon they are getting fat and the vicious circle has started...haertbreaking Reply @alexremix @alexremix 3 months ago Where are the hot springs located? Reply @sheilahollinshed933 @sheilahollinshed933 5 months ago Your not saying how it go from person to person Reply @livefree3864 @livefree3864 2 years ago (edited) FACEBOOK MARK IS EVIL! CAN YOU PLEASE LEAVE POLITICS ALONE AND WORRY ABOUT HEALTH...... 2 Reply 1 reply @maryhanger4519 @maryhanger4519 3 months ago Dr Hyman, please ask someone you work with to change this picture of yourself on this YouTube video. The picture makes you look very ill Reply @KKing55 @KKing55 4 months ago Change the FDA~!!! Reply @jessicalugay25 @jessicalugay25 8 months ago Dr Sabi told u all 1 Reply @kymberlybade1480 @kymberlybade1480 6 months ago I dont agree w your idea for censorship. Why dont you Einsteins get together and make things like high fructose corn syrup illegal. You are insane if you think the average working American can keep up with all the information concerning food additives, preservatives, cooking methods. Reply @CP-nf9my @CP-nf9my 2 weeks ago Lost me at, "takover of the Capitol." Seriously? Yep, that inflames people who know it didn't happen. You're part of the problem. Reply @vincentrevers3004 @vincentrevers3004 2 years ago LoL some useful information but to much EMOTIONAL B.S. 4 Reply @michaelmelamed9103 @michaelmelamed9103 3 months ago It all Reply @starr8111 @starr8111 2 years ago Not listening without time stamps 5 Reply 1 reply @alyciahall1111 @alyciahall1111 8 months ago He just doesn’t look that healthy to me Reply @conniecox9695 @conniecox9695 2 weeks ago Abortion? Reply @Adam-sj9bk @Adam-sj9bk 1 day ago i was enjoying this until you brought politics into the discussion Reply @kevinkelly1529 @kevinkelly1529 1 month ago (edited) So much of this guy's laughter is insanely inappropriate! 36:20 How can he burst out in laughter about 80 million American children being molested? If this is a nervous condition causing this vulgarity , at the very least the audio should be cleaned up before posting! If this laughter is sincere, this man needs to be removed from the internet and given psychiatric help. Ask one of us 80 million if we thought the molestation was hilarious or not! 1 Reply @Ag-wu4mi @Ag-wu4mi 7 months ago Fermented vegetables Reply @rebekkaninan5123 @rebekkaninan5123 2 months ago These talks are too long. I can't get the main points bcoz your discourse is full of jargon. Do post some bullet points at the end Reply @TaylorJohnson-ip8dt @TaylorJohnson-ip8dt 2 years ago Its really upsetting watching people listen to this guy. I mean come on his functional medicine approach is no different from alternative medicine, just spruced up with a different name. Since the 2000s Americans have gone from one alternative form to the next, and what have we to show for it? Nothing! His whole approach to sell testings is highly unnecessary in the eyes of a professional. He jacks you up on supplements which are also unnecessary. Not only are his methods unnecessary, they are costly to the patient. It's really upsetting seeing this guy talk about leaky gut syndrome, which is not a real disorder. Intestinal permeability exists, but this is not a cause for autoimmune disorders only a symptom. Everything this guy talks about is not scientifically based. 2 Reply 3 replies @terrytay1774 @terrytay1774 2 years ago He isnt saying anything new! Yawn... Reply @heyday179 @heyday179 3 weeks ago blahblah blah . how did you get rid of the mercury poisoning. 1 Reply @345kobi @345kobi 4 months ago 33 Reply @benjaminbritt7862 @benjaminbritt7862 2 years ago Poo poo pa pa :) 1 Reply @mariasvlog9425 @mariasvlog9425 1 year ago Yay Reply @irenadurakic-edwards9577 @irenadurakic-edwards9577 2 months ago Your guest has inflamation in nose and mouth definatelly as talks heavily trough the nose and has to much saliva!Hard to listen but forsed myself.. Reply 1 reply @MsKarenrankin @MsKarenrankin 2 years ago Still way off Reply @frankie57 @frankie57 1 month ago TUMERIC Reply 1 reply @tlouandtherest4378 @tlouandtherest4378 5 months ago 2 rookies Reply 9+ Avatar image 1:14 / 1:59:31 These FOODS & HABITS Boost Brain Health & REDUCE INFLAMMATION | Mark Hyman Dhru Purohit 434K subscribers Subscribe 7.7K Share Download Thanks Clip 398,456 views Apr 28, 2022 Sign up for my FREE weekly newsletter to improve your health: https://bit.ly/TryThisNewsletter If you haven’t heard, me and Dr. Mark Hyman have been teaming up to do weekly podcast episodes called “Masterclasses.” We sit down and have deep conversations about the most important health topics of our time and give you all the answers you’ve been after. This week on The Dhru Purohit Podcast, I am featuring two of our favorite Masterclass episodes all about creating optimal brain health and reducing inflammation. We talk about the top foods to avoid—and to enjoy—to optimize brain health, why sugar is so bad for the brain, and how toxins can lead to neurodegeneration. Then we break down the meaning and function of inflammation and how it manifests as heart disease, cancer, diabetes, depression, and more. Dr. Mark Hyman is a practicing family physician and an internationally recognized leader, speaker, educator, and advocate in the field of Functional Medicine. He is the founder and director of The UltraWellness Center, Senior Advisor for the Cleveland Clinic Center for Functional Medicine, a fourteen-time New York Times bestselling author, and Board President for Clinical Affairs for The Institute for Functional Medicine. He is the host of one of the leading health podcasts, The Doctor’s Farmacy. Dr. Hyman is a regular medical contributor to several television shows and networks, including CBS This Morning, Today, Good Morning America, The View, and CNN. He is also an advisor and guest cohost on The Dr. Oz Show. This episode is brought to you by Pendulum: https://pendulumlife.com/ Cozy Earth: https://cozyearth.com/ Pendulum is the first company to figure out how to harness the amazing benefits of Akkermansia in a probiotic capsule. To receive 20% off your first purchase of Pendulum’s Akkermansia probiotic supplement, go to https://www.Pendulumlife.com and use code DHRU20. Cozy Earth are the most comfortable, temperature-regulating, nontoxic sheets on the market. Right now, get 40% off your Cozy Earth sheets. Just head over to https://www.cozyearth.com and use code DHRU. Social & Website Instagram: https://www.instagram.com/dhrupurohit... Twitter: / dhrupurohit Facebook: / dhruxpurohit Facebook Community: / 2819627591487473 TikTok: / dhru.purohit Website: https://dhrupurohit.com/ YouTube: / dhrupurohit Text: 302-200-5643 or click here https://my.community.com/dhrupurohit Dr. Mark Hyman Instagram: / drmarkhyman Facebook: / drmarkhyman Twitter: / drmarkhyman YouTube: / drmarkhyman Website: https://drhyman.com/ Key moments View all Transcript Follow along using the transcript. Show transcript Dhru Purohit 434K subscribers Videos About 1:40:11 #1 Neuroscientist: Truth About Laziness, Discipline, Exercise,Stress & Journaling | Andrew Huberman by Dhru Purohit 1:39:34 How Insulin Resistance DESTROYS Your Brain & Causes ALZHEIMER'S / DEMENTIA! | Ben Bikman by Dhru Purohit 1:52:39 The 4 Secrets to AGE IN REVERSE & Live Longer TODAY! | Dave Asprey & Dhru Purohit by Dhru Purohit 1:50:11 Jason Fung & William Li REVEAL The 4 Steps to PREVENT DISEASE! by Dhru Purohit 373 Comments rongmaw lin Add a comment... @DhruPurohit Pinned by Dhru Purohit @DhruPurohit 1 year ago Get my FREE guide Raise Your Omega 3's when you sign up for my weekly health newsletter at dhrupurohit.com/omega3 36 Reply 12 replies @lawrencecheng5677 @lawrencecheng5677 3 months ago I was born in Hong Kong and am 65 years old. At the age of 60 when I retired, I was nearly 200 lbs (with a height of only 5' 5")! Accompanied with Atrial Fibrillation, very high blood pressure and liver inflammation, I had been very dependent on medical prescriptions since 50 years old. You can imagine my health status. I began to learn on the Internet after retirement and started intermittent fasting (16/8), drinking black coffee, extra virgin coconut oil and even MCT oil (in order to alleviate hungry feeling). I usually skip breakfast with only 2 boiled eggs and bullet proof coffee as my lunch. Within a fortnight, it began to bear fruit. I obviously lose weight at an average rate of 2 lbs every week. I occasionally adopted 20/4 IF. The result was even more amazing. In one year's time, I shred almost 80 lbs. Together with the help of daily intake of MCT oil, black coffee, brisk walking, light dumbell exercise and being vegan, I feel great again. 63 Reply 1 reply @ladyc3205 @ladyc3205 6 months ago This is an outstanding interview. I’ve been looking at many health related videos for help to get rid of excessive weight and inflammation in my body. This explains so much on the value on eating simple and real food and insulin resistance on the body. I worked around researchers and doctors most of my adult life and not once did any of them ask about what I was eating. Functional medicine is a game changer. I’m grateful and thankful for this video and sharing with family and friends.💯 29 Reply @kellio8087 1 month ago Choosing an anti-inflammatory diet and supplementing, healed my chronic inflammation, hypertension, muscle cramps, muscle spasms, and twitches and gut issues. Based on my experience, Dr Hyman's spot on! 5 Reply 1 reply @barbarailarpenter6815 7 months ago To the nurse who wrote about alcohol: Thank you!! And being a nurse is something to be proud of! It is a big deal to the person who made a smart remark. Be kind, everyone. You don't have much time on this earth, and no one likes a jerk. 63 Reply 2 replies @VK-vd8qz 1 year ago (edited) Dr Mark you are like a General Hospital.Your have explained all the problems i am facing now step by step and very clearly. Lately i realised the root cause of my problems but your explanation is very very clear. I dont think so any paid specialist will explain this deeply. I felt my organs were dropping one by one 2 yrs ago and still struggling. Now, i understand how bad is inflamation to rhe body. Your video is quite long but it is not boring because each words and sentences are very useful and important..Thank you very much and please post more videos. Dhru Purojit i have subscribed you channel. Keep it up. 33 Reply @theantiqueactionfigure 6 months ago (edited) Mark Hyman's medical situation was nearly identical to mine, although I'm a long way from recovery at this point. I feel that my through the roof lead levels and elevated mercury were the root cause of my Chronic Fatuge Syndrome which began about twenty years ago. This podcast is motivating to get my chelation therapy restarted. Just not looking forward to the Herxheimer that it always put me through. 8 Reply @myrnaleon8464 2 months ago Another excellent, comprehensive video from Dhru. Thanks for featuring Dr. Hyman in this series. 😊❤ 7 Reply @debbiefarrar7356 7 months ago Thanks so much to you both so interesting Listening to this and other podcasts are helping me heal after a stressful life and a stroke Now lm on a better journey learning all the best foods & exercising and learning not to stress is helping As they say stress kills and my stroke was a wake up call. Walk away from toxic partner and toxic people. I was bought up by toxic mother and didn’t know any different Also childhood trauma and lots of awful things happened sexual abuse And marriage of domestic violence Now lm 60yrs old and turning my life around 33 Reply 2 replies @user-dv2rj6gx7m 3 months ago Thank you for giving all information to people, I am Austrian, and we dont eat processed food, maybe only sometimes. Our food should be organic grown without pesticids and fertilizer. We cook every day fresh and enjoy our meals sitting around table with our familymembers. 19 Reply @wmalinowymstylu7670 5 months ago I haven't eaten sugar since 2018, and I feel totally different. The bitter fruits or veggies don't have this strong bitterness. Bitter herbs like wormwood are not so bitter like 5 years ago when I started drinking. My brain is really working differently, faster, better concentrated, I see colors clearer and intense, I'm not stressed anymore, no panic attacks, less stomach problems etc etc....I have thought out from my diet gluten and lactose. No more unexpected diarrhea in my life 😆. Of course, I'm still taking other supplements, but the good one, and I feel amazing. People, please open up your eyes🙏Wake up! Life without white sugar is more beautiful. And who has donn it knows what about I'm speaking 😊God Bless u all, Monika 16 Reply 3 replies @victorallicock3154 6 months ago Thanks for you guys for a very informative and well presented interview. I am hooked on this video and will put this info, into action immediately. God bless you both. 6 Reply @ekiggai3805 1 year ago Dr Mark, thank you so much for sharing this priceless information. Thank you Dhru for organising this podcast.. I am using this inf. helping someone in trouble. 28 Reply @mariaolsen39 1 month ago Thank you for all this valuable information and the time you give to educate people. I am grateful to you both for these wonderful chats. Unfortunately, Continuous glucose monitors are not an option in my country. They cost a small fortune in continuous fees, and you have to be a diabetic to get one. One day they will become more accessible to everyone. Reply @cassondrad2280 1 year ago (edited) Thank you. It comes down to the "root cause" of inflammation, childhood trauma, what are you feeding your body, sleep, stress, relaxation. Thanks 17 Reply 1 reply @19squidgy75 5 months ago This resonates at with me completely, every single word he speaks is 100% true. My breakdown started on 13/1/2020, I am slowly digging myself out of this hole 🕳️ 3 Reply @kathycole1 1 year ago Highly intelligent! It is so amazing to see healthy results through clean eating. Thank you for your wisdom. 11 Reply @RichardAlsenz 1 year ago I am a theoretical physicist, not a medical doctor. I enjoyed this discussion very much. I am concerned that the issue of viscosity in body fluids is not considered in discussions of inflammation. Acidic production within the body reduces the flow of body fluids. The lack of oxygen in the body fluids seems to be a significant obstruction to the healthy flow of body fluids due to this inflammatory viscosity reduction. Microbial byproducts appear to be the primary producers of acids and seem to be the most likely sources of inflammation. Inflammation seems to have many health benefits, yet it also appears to be a significant heath problem generator. Otto Warburg spent a significant amount of his life on this effect within the cell membrane, yet the issue is more relevant outside of the cell membrane. For the oxygen to support cell reproduction, it must get to and within the membrane. I would be very interested in hearing your comments on this subject. 14 Reply @sazennonumber 5 months ago This was great, thank you. Even if some listeners have heard of all of the mentioned recommendations, it is well rounded up, super-inspiring and helpful. 2 Reply @kathycaruso1587 1 year ago Great information, you give the average person tools and power to improve their health and lives! 16 Transcript 0:00 the brain responds to everything we do what we think what we feel exercise sleep our diet environmental toxins 0:06 stresses all these things influence our microbiome everything influences the brain let's start off with delivering some 0:12 immediate value to people three things that people can eat or potentially not 0:18 eat that's directly tied into having a better brain very important because one of the best 0:25 ways to access brain health is through our diet both what we eat and what we don't eat 0:31 let's start with the don'ts uh the most dangerous thing for your brain is sugar and starch 0:38 those cause inflammation in the brain they cause dementia they cause depression 0:43 they cause behavior issues they're really nasty for the brain so it doesn't mean you can't ever eat them but think 0:50 about those things as recreational drugs as i've said so starch and sugar the third thing you really want to get 0:56 rid of is bad fats so trans fats are very dangerous they're still in our food supply even though they've been 1:02 regulated as not safe to eat they're still out there and a lot of refined processed oils so 1:07 those would be the things that i would avoid number one and of course processed food that just kind of goes without saying and what are some examples of 1:14 those refined and processed oils so my favorite is what they call vegetable 1:19 oil you go to the grocery store and it says vegetable oil what is it broccoli oil no 1:24 it comes from seeds it comes from sometimes even cottonseed oil which is highly toxic 1:30 it's canola oil it's soybean oil 10 of our calories come from soybean oil it's increased a thousand percent in our diet 1:36 didn't even exist as a real food in our diet until probably 1900 1:41 early 1900s so we really entered an era where we are eating a diet that is so 1:47 different than we have for almost all of our human evolution and those fats tend to drive inflammation 1:54 they're easily oxidized they go rancid they're made with extraction processes that have hexane 2:00 and they're they're often causing significant inflammation and damage in the body and just so people are aware 2:06 it's not that they're necessarily going out there and buying these oils cooking with everything they're in everything and everything so you have to be a 2:12 student of ingredient labels and pay attention to all the processed foods that are out there because a lot of them 2:17 are big are going to be fighting against your brain yeah the easiest trick is just don't eat anything processed unless you know what's in it like i mean if you 2:24 have to have a list of ingredients probably i mean yes there's some packaged food that's fine but if you have to know what it's in it so if it 2:29 says some big chemical words you don't can't recognize it or you've got 14 000 things on the label probably not what 2:34 you should be eating anyway great so those are three things to avoid okay so you were going to go into the 2:40 topic of three things that we can pay attention to so most people don't know this but your brain is mostly fat you 2:46 know we really are all fat heads and about 60 of our brain is made of fat and most of that is what we call dha or 2:54 docosahexaenoic acid sounds like a big chemical name but essentially it's fish oil 2:59 it comes from algae too you can get it from algae so if you're plant-based you can get it from algae but it is the main 3:04 ingredient for a healthy brain and so we need to be eating fatty fish that's glow in mercury we need to be 3:10 eating algae we need to be doing things that actually help boost our dha levels the second thing is good fats in general because our brain 3:17 actually responds really well to fat mct oil for example is the derivative of coconut oil that's really great for the brain's energy system and can help 3:23 improve cognitive function it also performs athletic improves athletic performance the third category of foods 3:29 we should be focused on are phytochemicals there's 25 000 compounds in plants maybe more the rockefeller 3:35 foundation is now doing the periodic table of phytochemicals they're spending hundreds of millions of dollars to map 3:41 out the medicinal properties in these foods but it's really easy when you think about it just eat the rainbow if 3:47 it's colorful and it's not skittles it's okay to eat so all the dark colored vegetables greens 3:53 blues purples reds yellows those foods that contain these pigments are full of 3:59 these phytochemicals and they're really extraordinarily helpful in regulating brain function in so many different ways 4:05 as a bonus one how about hydration it seems like that's one area that's often overlooked you know one of the things that uh often 4:12 people forget about is the bottom of the matrix in functional medicine which is the sort of the map we use to figure out 4:18 what's out of balance for people and hydration is really really important because most of us walk around 4:24 dehydrated most of us don't drink enough water we have other fluids like sodas and juices and coffees 4:30 and teas but we don't really have enough water and often when we do we're not getting intracellular hydration which is 4:38 so critical so not only in your bloodstream but inside your cells which is what makes you feel good so it gives 4:43 you energy and performance so my favorite um athletic performer is tom brady and he 4:49 never drinks water without electrolytes maybe that explains his seven super bowl 4:54 rings i don't know but i agree i i've using electrolytes in your water is so 5:00 important and not the kind with tons of sugar and all kinds of weird stuff my favorite one i have no affiliation with this brand it's called light show 5:06 lytee show but it's simply liquid drops you can put in a glass of water and i every time i drink i try to add those in 5:13 and there's a portable container you can take your little drops with you so intracellular hydration is really really important and it's important for your 5:18 cognitive function it's important for energy it's important for everything one caveat on water naturally as the 5:24 world and especially here in the united states unfortunately too has more and more infrastructure challenges 5:30 more of the water that's out there is corrupted so just another reason that people should really invest in a high 5:36 quality filter i heard somebody say one time either you get a filter or you become the filter that's a good one 5:42 yeah i think it's right i mean i i mean i i remember reading a paper recently that showed that in the average tap 5:48 water there's 38 wastewater contaminants pesticides glyphosate medications i mean where do you think 5:54 all the women taking birth control pill or hormones or prozac or statins those get metabolized and they get excreted in 6:00 the urine where does that go it goes into our water supply that gets filtered cleaned and reused and we ended up 6:05 having all these wastewater contaminants and people don't have a clue about what they're drinking forget about the chlorine and the fluoride and all the 6:11 other stuff that's added to the water but there's a lot of inadvertent things in the water because of the level of toxicity in our society so i think 6:18 filtering water is is so key um obviously if you're drinking water bottled water 6:23 is a problem because one um it's usually plastic which is not something we need more of in the world 6:29 glass bottles are okay but getting a filter is really important so let's zoom out really quickly how big of a problem 6:36 is poor brain health and inflammation of the brain really that is a very important question 6:42 because a lot of the diseases that we see that are causing disability 6:48 lastic productivity loss of quality of life are brain disorders 6:54 whether it's anxiety depression the opioid epidemic neurodegenerative diseases like 7:01 alzheimer's parkinson's and all the cognitive disorders like adhd autism 7:08 these are all diseases of inflammation of the brain and they're rampant if you look for 7:13 example just a depression our modern tools really suck at treating it i mean if you have severe depression 7:19 sometimes medications can help but for most people you look at the data maybe 30 effective not much more than a placebo 7:25 and the question is what's driving that problem it's it's all our inflammatory lifestyle which we've talked about a lot 7:30 on the podcast and it's it's it's one of the most important things one in four people have a severe episode of 7:36 depression their life in the world it's uh accounts for the majority of the costs in our health care and all the 7:43 collateral symptoms that we have from from the externalities of depression like loss of productivity so 7:49 there's a macro economic analysis looking at over the next 30 years what's it going to cost for chronic disease 7:55 it's 95 trillion dollars with a t okay that's a lot of dough that's you know 8:01 way more than the gdp of the top nations in the world combined probably twice that of all the top six nations combined 8:07 that amount of money the majority of that is for depression because of the loss of productivity the 8:12 effect on society and so forth so these are rampant conditions one in 10 kids have add alzheimer's you know we 8:18 probably have alzheimer's or pre-alzheimer's and 40-50 million americans depression affects you know more than 60 8:24 million people but throughout people's lifetime it's super common we're seeing we're seeing a 8:29 rampant increases in autism in neurodegenerative diseases so we we have to grapple with this problem on 8:35 brain health and in a more focused way because it is the thing that we need to operate 8:40 in our lives to be happy to have healthy relationships to do the work we want to do in the world to be a functioning 8:46 member society to be engaged and not just be in a spiral of 8:51 a near vegetative state sitting on the couch watching tv because you feel like crap so there is there is enormous 8:57 opportunity to sort of pull the veil back and and rethink our whole approach to brain health now one of your first books was ultra 9:04 mind solution and one of the core ideas in that book was what you do to the body 9:09 you do to the brain yeah can you expand on that what did you mean by that well the title of the book was the ultramine solution how to fix your broken brain by 9:16 fixing your body first because unlike what we learned in medical school 9:21 which is that our head is and brains are sort of this disembodied thing on the top of our shoulders 9:27 and it doesn't connect with anything that's going on below there we've learned that that's completely untrue that we're learning that the 9:33 brain responds to everything we do what we think what we feel exercise sleep our 9:39 diet environmental toxins stresses all these things influence our microbiome everything influences the brain 9:44 so we we really have to sort of think about how do we re sort of equilibrate to a different 9:50 way of thinking about brain health based on all the things that we can do to fix the imbalances in the body that affect the 9:57 brain whether it's thyroid whether it's your microbiome whether it's toxins whether it's low nutritional levels of 10:04 certain vitamins and minerals like fish oil or omega omega-3s or vitamin d or the b vitamins so we know a lot about 10:11 the things that make the brain healthy we call these trophic factors these are things that help the brain grow and improve and increase neuroplasticity and 10:17 neuroconnectivity there's so much that's exciting that we know about how to do that and yet most of us are poisoning our 10:24 brains and we think oh i know i for my heart i have to exercise i have to cut out saturated fat i have to you know do 10:29 all that and i can prevent heart disease but most of us have no clue how to take care of our brain or live a brain 10:35 healthy lifestyle you know we just don't learn it what are a couple examples of things that people are doing today separate 10:41 from like the topic of foods right that are some of the biggest contributors to poor brain function in 10:48 their life overall well the low-hanging fruit is lack of exercise eight percent of americans get adequate exercise that 10:54 leaves you know 92 percent who needs some help and the exercise is really extraordinary 11:01 because when you do cardiovascular exercise you do strength training you do hit training and specific kinds of exercise 11:09 it increases these incredible molecules in your brain called bdnf 11:15 bdnf stands for brain derived neurotrophic factor think of it like miracle growth for your brain 11:20 so when you exercise you're literally increasing the number of brain cells you're increasing the connections between the brain cells you're 11:25 increasing your cognitive power exercise is super critical so that alone can make a huge difference 11:31 for so many people the second thing is sleep if we don't sleep our brains don't work and i remember the study i read recently that 11:38 looked at sharpshooters in the in the military the snipers essentially who are super accurate like 99 accurate when 11:45 they have eight hours sleep when they get seven hours drops off a little maybe ninety percent less six hours starts to 11:51 go to like forty sixty fifty percent at under six hours it's like basically hit or miss 11:58 it's 50 and so we really don't understand how important sleep is to cleaning our 12:04 brain to repairing our brain to getting rid of the garbage the garbage man comes at night when 12:09 we're sleeping to clean out all the metabolic waste that our brain makes during the day and if you don't have adequate sleep you're not going to be 12:15 able to do that the third thing in addition to exercise and sleep is stress we know that chronic stress now we all 12:22 have acute stresses but the chronic unmitigated stress of our modern life and whether it's coming from the world 12:28 we live in all the chaos whether it's coming from inflammation and stress that our diet causes because our diet 12:33 literally causes us to build more adrenaline and cortisol in our body like high structured sugar diets whether it's 12:39 our senior lifestyle all these things drive our our brains to to not function properly 12:46 and so the stress response is something we know how to deal with we know how to actually reset the body by activating 12:53 the part of your nervous system that is the relaxation response we call that the parasympathetic system as 12:58 opposed to the fight or flight or freeze response it's you know playing possum you know basically and and it's not just 13:05 sitting on the couch watching tv drinking a beer uh it's actually a very active thing so it could be meditation 13:11 it could be yoga it could be my favorite or more passive ones like massage hot and cold plunges there's a 13:17 lot of ways to access the nervous system to help reset it to create a deep sense 13:22 of profound relaxation that's physiologic and that helps you repair your brain because if you have chronic stress it literally shrinks your brain 13:30 it shrinks the hippocampus in your brain which is the memory center so we know that chronic stress causes dementia so 13:37 just just that alone can have a huge impact those three things and then there's a huge long list that goes on 13:42 and on but dale bredesen who um one of my favorite people he's a 13:49 credible neurologist who studied alzheimer's and has used functional medicine to reverse not just to stop or 13:55 slow but to reverse alzheimer's in patient after patient and he talks about this idea called a 14:00 cognoscopy which is how do we get a colonoscopy but how do we measure our brain function well there are some really specific 14:07 simple online tests neurocognitive tests you can do there are ways of looking at brain imaging there's certain lab tests 14:12 and things you look at to see what are the threats to the brain how do you how do you assess the threats and it's 14:18 important because when you start to understand how the brain works you can really play with it 14:23 and see conditions reverse that you just never would see i mean i i mean i only wrote ultra mind solution 14:30 because i was treating people's physical problems and as a side effect their brains would 14:36 get better and i'm like what happened like someone for example would it be having 14:41 panic attacks and anxiety and depression and i would get their insulin under control and their microbiome under control and they go well i don't have 14:47 that anymore i'm not depressed i'm not anxious or they have bipolar disease and i did this this and got better or they'd 14:53 have adhd or autism or alzheimer's and they start to really improve or completely recover i'm like what's going 15:00 on here this is not what i learned in medical school and so i began to really through the inquiry of my own patients 15:06 and their data and their experiences and applying functional medicine was able to sort of map out how all this connects 15:12 and all the things that affect the brain and it's not just um it's not it's not it's not just the 15:19 obvious things but there's a lot of things that we can we can dive into around infections and the microbiome and 15:25 toxins and other things that affect brain health so the fundamental things are easily accessible to everybody and 15:30 we all should think about not only how do we take care of our body and our weight and our heart risk but also our brain health and and 15:37 there's some very specific things you can do to do that now this topic is near and dear to you because you write in your book that not 15:43 only were you focused on helping on your patients but you were trying to help yourself your own brain 15:48 broke so i'd love for you to take us down your story and also while you go through it help us 15:55 look at the whole talk topic of brain related disorders and how conventional 16:01 medicine might see it and how functional medicine might see it first i'll start with my story because it helped teach me so much about 16:07 how the brain breaks and what to do to fix it uh when i was in college you know a student got into medical school school 16:14 was easy for me i barely studied and my brain was just like a steel trap and i remembered 16:19 everything could focus pay attention uh he was happy i mean just my brain was good 16:25 i exercised i ate healthy i did all the right things i did yoga 16:30 and then i went to china and got mercury poisoning which i didn't know at the time came back and got some other insult that 16:36 trick tripped my system into really being sick and and all of a sudden i went from 16:43 completely functional to completely dysfunctional i couldn't sleep 16:49 i even though i was exhausted and had chronic fatigue syndrome i couldn't focus like i had adhd 16:56 i couldn't remember anything i was got depressed uh so it was like i had depression atd and dementia all at 17:04 once and i would literally be reading my kids a story at bedtime and i couldn't 17:09 understand the sentence if i read it out loud i literally would not be able to understand what i was saying my brain 17:14 didn't work or when i was talking to somebody i would start a sentence and i didn't know where i didn't really know where i was going i didn't finish the 17:20 sentence i was really damaged and so through understanding my own biology and reverse engineering my 17:27 way to health i began to understand you know all the factors that affect brain health and that's really why i 17:33 wrote the ultramine solution because it's what i learned on myself but it's also what i began to see on nearly thousands of patients 17:41 talk to us about some of those root factors that were going on for you that might be beneficial for other people to hear what was going on in your life that 17:47 contributed you to being in that place in the first place well i had a bunch of stuff i mean i i i was in a 17:55 crazy work schedule i was working as a er doctor after i came back from china 18:01 not sleeping you know i literally would was doing 15 shifts a month it doesn't sound like a lot but it's a lot i was staying up all 18:07 night many many nights i would i was taking care of my two kids my ex-wife was an alcoholic and it was really a 18:12 tough moment a lot of stress and a lot of work and a lot of sleep deprivation and then i would you know go to the emergency room and i would have at 11 18:19 o'clock to 7 a.m shift at night and i would drink a quadruple espresso a giant chocolate chip cookie 18:24 and a half a pint of ice cream and i'd get in the car and i'd drive to work and i last probably until five in the morning hopefully it was quite if i 18:30 could take a nap uh and i did that for years uh and so between that stress between 18:36 the difficult stress in my life in terms of my marriage and also this mercury underlying mercury toxicity 18:42 that men got tripped into full expression when i had a severe intestinal infection 18:49 that was sort of the straw that broke the camel's back and ended up just cascading into years and years of me 18:54 trying to figure this out and i got terrible diarrhea for your sibo bacterial overgrowth my muscles were getting damaged my 19:01 immune system was dysregulated i started getting sores on my tongue rational on my body autoimmune antibodies my liver 19:06 function went up i mean my whole lab test looked terrible and i was a mess uh and doctor after 19:11 doctor was like well you're depressed take prozac or you're anxious take xanax or you can't sleep take ambien or you 19:18 know it's like i was it was that and i remember uh and i started getting weird fasciculations and all kinds of 19:23 weird symptoms and my my muscles were twitching and my muscle enzymes were really high which means my muscles were being 19:28 damaged and i remember going to colombia and seeing these top neurologists who was an expert in this 19:35 type of thing and they ordered a test called the emg which is no fun essentially they stick giant needles in your muscles and they 19:42 then send electrical currents down them to see what's going on and this guy was this old british doctor 19:47 there who was joining the test and he said oh you have been benign fasciculations 19:53 which means your muscles twitch but it's not serious it's not als which because it could it could have been als 20:00 and uh and the uh and he goes off the record this isn't normal like there's no such 20:06 thing as benign fasciculations you don't have ls but it's something else you know so that and that was even 20:12 before i figured out the mercury thing i just i just didn't know what's going on i was searching and searching searching so it took a couple years for me to 20:18 actually figure out the mercury thing before i was able to get better what was part of that turnaround process 20:24 which also was the introduction for you into the world of functional medicine like how did you begin to look at things differently and then start to treat 20:30 yourself well that was always a little weird i mean i always you know i studied nutrition in college and it was a yoga 20:35 teacher before i was a doctor i was interested in integrative health i didn't recall that then um and i was 20:40 always exploring the edges studied ancient healing systems chinese medicine so i always had a different framework that i was coming from when i went to 20:46 medical school uh and then when i um got a job at canyon ranch it's right when i 20:52 got sick uh and i met a woman named kathy swift who's a nutritionist there and she's 20:57 like you gotta come to this lecture from jeffrey bland and i'm like okay and so i went to hear this guy speak and 21:02 i listened to him and i thought this guy's a genius or he's a lunatic and if what he's saying is true it it 21:10 means that everything i learned needs to be reexamined questioned and reimagined and i need to prove that to 21:17 myself and my patients so i said i'm going to try it on because if he's right it's a game changer if he's wrong he's 21:23 just a nut who's promoting a lot of stuff that's kind of goofy and it turned out he was right 21:29 and the rest is history and that's when we really started diving into functional medicine at canyon ranch we had a great 21:35 incubator where we could spend hours with patients i could dig in all these things they could learn everything they were willing to do stuff and so it was 21:41 really a great incubator and then i just kept going down that rabbit hole and healed myself and started healing 21:47 thousands and thousands of patients so what was one of the first things and we're going to touch on your story but these are also things that people can 21:54 walk away with when it comes to their own story too so was one of the first things that you did when it came to your 21:59 diet you're eating chocolate chip cookie double espresso you know you had all this sugar in your diet what was one of 22:05 the first things you did when it came to your diet uh well i i literally had to do an elimination night because the 22:11 mercury not only affected my brain it affected my gut which by the way they're totally connected right there's called 22:16 your second brain there's more neurotransmitters in your gut than your brain there's more nerve endings in your in your gut than your brain it's really 22:22 quite fascinating and my gut was a mess and so i developed leaky gut i developed sibo which wasn't 22:28 even a thing at the time small intestinal bacterial overgrowth fungal overgrowth i would eat anything and my stomach 22:34 would just blow up like a balloon like i had gas it it just wouldn't come out and i felt like i was had you know like a 22:40 giant sort of tire inflator that just blew up my intestines uh and it was painful and 22:46 difficult and i had diarrhea and digested food my stool and just kind of a mess so i literally had 22:52 to dramatically change my diet to just be able to 22:57 tolerate any food so i used turkey broccoli and brown rice for like a year just to kind of calm my system 23:03 down it didn't really help get rid of all my symptoms but it just helped them not be so bad and i until i got rid of the mercury my gut couldn't heal and 23:10 it's not that you're necessarily recommending the turkey brown rice diet to other folks you're just talking about what you do i'm just saying like my 23:16 stuff my system was so dysregulated i couldn't eat anything without causing a rash or my eyes like turning like a 23:21 raccoon black or a swollen tongue or my whole system was just 23:27 messed up and in order for me to just reduce my diet to them the most 23:33 um simple foods that were not going to be triggering reactions i had to really simplify my diet 23:39 so that's what you did then if you were your patient today what would you do for that person that same situation when it 23:46 came to the topic of diet if i had me as a doctor when i first started this i would have been better a lot faster 23:51 i wish i but like i literally had to crawl my way through knowing and by that was really tough drew because 23:57 not only was i sick but it was very hard for my brain to work so i literally had to despite 24:04 having my brain barely functional still try to learn and focus enough to try things and it was 24:10 really tough it was really really just like kind of like trying to like um you know get out of a very deep hole and 24:18 a black hole and it was tough because i didn't i didn't have the full capacity of my mind 24:23 so i started to learn things and i started to incorporate things it was very slow and it took me a number of years before i even figured out that i 24:29 had mercury poisoning and i ended up sort of being in a functional medicine 24:35 conference and i met a guy on a plane who was a naturopath and he was he was like well come into my 24:41 office because maybe i can help you i told him what's going on so he did this machine this electrodermal screening which sounds like total quackery but 24:47 it's looking at the bioenergetics of different meridians and different electrode uh electromagnetic frequencies 24:52 in your skin which are there and he said well it seems like you have metal toxicity i'm like really okay and then i 24:59 went to my friend mark david and i said i was just sitting at his house i'm like can you do my hair analysis and see what's up and he took a little hair we 25:05 sent it off and it was really high and then i did a challenge test and i found i had a level that's you know i've done i've probably done 20 000 of these tests 25:12 over the last three years and it was probably in the top top 10 20 tests i've ever seen of the worst levels 25:19 and then i then that was when i started to detoxify but it was really tough because i didn't have a road map i was 25:24 just sort of figuring things out we didn't even understand what sibo was back then we didn't understand a lot of 25:29 things that we didn't know now we didn't have a lot of the tools we have now so that would probably be a lot better a lot faster so you mentioned mercury you 25:35 know mercury is part of these environmental toxins that are out there and it can come from a lot of different sources we'll touch on that in a second 25:41 but mercury is is part of uh you know a ton of 25:47 chemicals that are in the environment like these pufas forever chemicals that are there we have 25:53 mold that can be environmental toxins with all the flooding and the buildings that we have um do you think that people 25:59 are paying more attention to this topic than you've ever seen before about how environmental toxins can play a role in 26:05 things like brain inflammation yeah i think there's more literature about the role of environmental toxins 26:10 in neurodegenerative diseases and autism and add in depression so there's there's 26:16 more and more science around this so i'm very hopeful uh but i do think it's still pretty much ignored i think people 26:22 aren't really trained in medical school to understand toxins other than acute toxicity uh so 26:29 chronic low-level toxicity that eventually overwhelms your system is just not something that's even 26:35 in the field of view of traditional doctors so for example i had this patient 26:41 recently who had autoimmune disease but she had very high levels of lead in her 26:47 blood and the highest level of lead i'd ever seen in any patient in 30 years and it was causing all kinds of 26:53 cognitive and also inflammatory symptoms and you know 26:58 the traditional doctors don't know how to look for that and test for that they can take a blood test but they rarely do that 27:04 but even if the blood test is normal you can still have a lot of stored toxins if you don't have current exposure so if 27:09 you don't for example if you don't fish for three or six months your blood levels will be good but you could have tons of stored levels in your body 27:15 i remember reading a new york times article about a group of soldiers that made their way to the cleveland clinic 27:21 and can you tell that story yeah well you know um special forces guys are 27:27 really not wimps you know these guys are navy seals who stand in ice water for three hours and you know one run a 27:34 hundred mile i mean these guys are just super human and there was a whole group of these guys who were really sick 27:40 and they were being kind of dismissed by the defense department and the va 27:46 and one of them came to cleveland clinic and i said well let's look at your story what's going on you're cognitively 27:52 impaired you can't focus you're depressed you're overweight your metabolism is messed up you have all these other symptoms 27:58 uh let's just see what's going on so i said what do you do he says well i'm a blast expert i blow stuff up and i teach 28:04 other people how to blow stuff up and we do it in enclosed buildings and when you blow stuff up and you make 28:09 bombs and guns you release lead mercury into the air and they're in there in a closed space with poor filtration 28:15 they're breathing it in to do this long enough you start to become poisoned and they came in and they were poisoned 28:21 and i was able to help these people get better it was really pretty miraculous and one of the story in the new york 28:26 times was was about this one soldier who went to i think was mount sinai where they have the lead expert who uses a 28:33 very specific technique it's only kind of in research which looks at the bone lead levels 28:38 which is kind of the best kind of measure of total body lead and and this scientist doctor at and it 28:46 was at mount sinai said look we we see this we can measure it but we never see it go down but when these patients came back to me 28:52 after being treated not only were they clinically better but their their levels of lead in the bone 28:58 went down i've never seen this before and of course you've never seen it before because most of us were never trained on how to 29:04 detoxify patients from heavy metals but when you know what to do you can remove the metals and these people get better 29:09 so now we have a whole group of people working uh with us or from the department of 29:14 defense and special task force dagger to incorporate these ideas into into the va and the 29:20 department of defense healthcare system so before we get back into neuroinflammation overall and brain 29:26 health overall let's just put a button in the topic of mercury and lead for most people it may not necessarily 29:32 be the first thing to look at unless if they're working with like a functional medicine doctor most people who are 29:37 listening are wondering like wow do i have you know mercury do i have lead it's an important topic to pay attention 29:42 to it's probably something that you need to be guided down the path of working with a trained practitioner who knows about that area and i think it's 29:48 important to say look with brain disorders whether it's the mood disorders anxiety depression 29:54 whether it's the intention of cognitive disorders like add and autism or the spectrum 29:59 whether it's the neurodegenerative disorders like alzheimer's parkinson's there are many factors that drive those 30:06 problems and and you have to look at all of them mercury is just one led is just one 30:12 those are final common pathways from multiple insults so if you take 10 people with depression 30:17 there may be 10 different causes for some it might be metals another might be a low vitamin d level or the fact that 30:23 they've taken antibiotics and screwed up their microbiome or maybe it's because they're taking an acid blocker and have low b12 or maybe they have gluten 30:30 intolerance and have built antibodies against their thyroid which causes depression so there's a lot of ways to get to the same end disease 30:37 so i always say just because you know the name of the disease it doesn't mean you know what's wrong with you 30:43 just because you have a label it doesn't mean you know the cause and the problem with modern medicine is what we call the name it blame entertainment 30:49 game we name the disease oh you have low mood you're crying all the time you're not interested in eating you don't want 30:55 to have sex you can't sleep you want to kill yourself oh i know what's wrong with you you have depression 31:00 but that is not the cause of your symptoms depression isn't the cause of your symptoms it's the name of your symptoms and then we blame the name for 31:06 the problem oh the reason you have these symptoms because you're depressed and the treatment is an antidepressant so we name it blame entertainment as opposed 31:13 to what i call thinking and linking which is where we start to begin to think about the cause not just wait uh 31:20 you know wait for people to sort of get on medication see what happens it's really a very important thing to understand for 31:25 people that that the same diseases can have many many causes and the same causes can 31:31 create many diseases so mercury could cause autoimmune disease can cause gut issues can cause depression it can cause 31:36 alzheimer's can cause autism but not all cases of autism or depression or alzheimer's are caused by 31:42 mercury so you have to kind of think about this kind of framework of one just because you know the name of 31:48 disease doesn't mean what's wrong with you two one cause can create many diseases and one disease can have many 31:54 causes so it's a really different framework for understanding human biology let's go back to one of the first things 32:00 you talked about which was sugar help us really understand how sugar is so deeply tied into this whole field 32:07 of neural inflammation and poor brain health what is it that sugar is actually doing in the body 32:12 okay you got a couple hours i spent my life studying this and it's 32:18 i'm gonna try to synthesize it but sugar is not necessarily bad if you have 32:24 a cookie or if you have a little bit of this for that once in a while it's not gonna kill you it's the dose that we have we used to 32:29 have historically 22 teaspoons a year as hunter gathers that means if we got 32:34 lucky we find a honey uh like a honey hive and we can get the honey or 32:40 you know we might find some berries in the summer and we'd get some sugar but historically we didn't have sugar as 32:46 part of our diet in 1800 we had 10 pounds of sugar per person which was still a lot 32:53 and now in 2020 we have about 150 pounds of sugar per person per year 32:59 so sugar when you have it at that pharmacologic dose is a poison and it does a number of things one 33:06 it screws up your microbiome so it it fertilizes all the bad bugs that create inflammation then that creates a leaky 33:12 gut and that creates neural inflammation it also drives a process in the body called insulin resistance which means 33:19 your body is resistant to the effects of insulin it's like the boy who cried wolf you eat a lot of sugar and starch and 33:24 your insulins go higher and higher and higher and the cells become resistant to the insulin so you need more and more insulin but the consequence of that 33:30 increased insulin is that you get more fat storage in the abdominal fat and the belly fat 33:36 and those fat cells are not just there holding up your pants they're very special kind of fat cells they're not 33:41 like the fat in your butt or in your thighs or whatever they're highly active organs they 33:47 produce hormones they produce cytokines you've heard of the cytokine storm from covets they produce all kinds 33:52 of inflammatory molecules like il-6 uh il1 and tumor necrosis factor alpha 33:58 these are very powerful inflammatory molecules that are coming from your fat cells so that drives systemic 34:03 inflammation throughout the body and you get neuro inflammation third we now know that in alzheimer's 34:09 disease that there's a huge problem with glucose metabolism and its insulin resistance of 34:15 the brain for many patients not all alzheimer's is some rest of the brain but they're calling alzheimer's type 3 34:21 diabetes now because of this impact of insulin resistance in the brain so there's a lot of ways and pathways 34:27 through which this causes a problem and and i'm not saying never have sugar of course i have sugar it's just what is 34:33 the overall balance of your diet is this a staple is this a daily commodity that you're 34:39 drinking for breakfast lunch and dinner i mean in america we have sugar for breakfast lunch dinner it's in our cereal it's in our salad dressings 34:46 it's in tomato sauce i mean there's more there's more sugar per serving of tomato 34:51 sauce than there is in two era cookies two oreo cookies so we've got to get kind of real and get all the hidden 34:57 sugar out of our diet i'd love to give you were so kind to share your own testimony earlier and 35:02 some of the things that worked for you let's talk about a couple other case studies from your practice of people you've worked with let's start first 35:08 with the topic of depression any case study that comes to mind well you know i i remember this one 35:14 patient who was severely depressed she was in her early 30s an executive coach and uh sort of 35:22 really struggling and and she had crippling depression she also had 35:28 sinus problems that were intractable she was overweight she was very inflamed 35:35 she had a lot of gut issues she had tons of yeast overgrowth and it was kind of miserable uh and she 35:42 came to see me and i took a look under the hood and found that she had 35:47 a lot of inflammation in her body that was secondary to high levels of mercury this patient had 35:54 really high levels of mercury like 300 which is mine was 187 this was not off the chart 35:59 and the the mercury was causing the weight gain because it's a metabolic toxin it was causing the gut dysfunction 36:05 because it poisons the gut it caused the yeast overgrowth which is because the mercury causes yeast overgrowth and it 36:12 caused her depression and so we systematically treated her by 36:18 cleaning up her gut in the yeast by clearing up mercury her sinuses got better the weight came off her 36:24 depression went away and it took a number of years to get that much mercury out of her body but i just saw her after 36:31 10 plus years and it's amazing she's still doing great so the the beauty is that is that you can take people with 36:38 really intractable problems if you know how to navigate to the cause which is what functional medicine does you really 36:43 can make a huge difference for these patients how about a kid or children with uh 36:49 you know a brain disorder somebody that have a case study that you worked with before well i have an autism case it's a that's a long story but i've seen kids 36:56 with autism get completely better using this approach because when you look at brains of autistic kids or people with 37:03 add they're inflamed there's a whole immune system in the brain called the microglia 37:08 and they can create an inflammatory process in the brain and on mri scans you literally see large brain swollen 37:15 brains on these kids when they do autopsy studies of kids with autism for a diet in a car accident or something they'll see their brains are filled with 37:22 these inflammatory cells and they're they're inflamed so the question is what's causing that inflammation and 37:28 kids with autism are like the canaries in the coal mine this one kid i saw was 22 months old when he started getting 37:33 symptoms we had regressive autism and he had you know a lot of antibiotics early 37:39 on you hear the same story c-sections like breastfeeding early antibiotics and then you know maybe getting 37:44 vaccinated when they're sick i'm not saying vaccines cause autism i'm just saying that it can be part of the mix that triggers a dysregulated gut and 37:51 immune system to go haywire and the whole field of vaccinomics which is fascinating which is looking at how 37:58 individuals respond differently to vaccines so this kid had terrible gut symptoms sticky smelly poops 38:04 he you know was non-verbal at two and a half he couldn't look at you in the eye he he 38:11 was just a mess um all the classic symptoms of autism i was told by the by the doctors just you know give them some 38:17 behavioral therapy good luck and you know eventually end up in an institution 38:22 because he had really severe autism so all i did was what i normally do is i i did my analysis of what are the factors 38:28 that cause disease what are the factors that are needed to help thriving and health what is he missing what does he need to get rid of the basic functional 38:34 medicine approach we found he had terrible gut dispose of three species of yeast he had leaky gut he had bacterial 38:40 overgrowth he had massive nutritional deficiencies in vitamin d and zinc and magnesium and 38:46 the b vitamins b6 b12 and he had a significant mercury in his system as well 38:52 so we began to treat these things we got rid of the metals in the system we fixed his gut we cleared out the bad bugs with 38:57 antibiotics and any fungals and we reset everything we gave all the nutrients he needed and b12 shots and this kid 39:04 literally became normal and i was like whoa this is crazy because i learned that autism is not reversible now that's 39:10 not to say that every kid will respond this way because there are many factors and i've seen 39:16 kids with autism that have more you know fixed problems that for example genetic and i look at all their lab tests 39:21 they're normal i'm like i don't know what to do because they're normal uh so there is there is a way to navigate the 39:27 brain health field by looking at all these factors and i've had kids with add that 39:32 completely normalized by simply getting them the things that they need for their bodies in their brains to thrive 39:39 let's do another one and that's on the topic of you shared about uh 39:44 alzheimer's earlier and sort of uh alzheimer's dementia all the neurodegenerative diseases that 39:50 increasingly more and more people are suffering from you had a patient that uh came to you um 39:56 and was a referral over who was a gentleman that was running a company and was thinking about retiring early 40:02 because his brain was so messed up talk to us about that yeah he was seven years old and uh you know he was in the book 40:08 ultramine solution was one of those cases that i had to sort of like rethink everything about my wife brought him in said look 40:16 my husband is uh basically non-functional he's a ceo of our company or a family health business he now sits 40:22 in a room alone depressed and demented and uh the kids don't want to be around him the grandkids are scared 40:28 of on me just not the human he was can you do anything i'm like i don't know let's try 40:35 so from the functional medicine perspective the beautiful thing about it is that it doesn't matter what disease you have you treat the system 40:42 you normalize function hence the word functional medicine and you see what happens and usually the 40:47 diseases get better so turned out that this guy had a lifelong history of gut issues he had irritable bowel 40:53 terrible bacterial overgrowth he was on a drug called stellazine for 30 years because his gut was such a mess and it's 40:58 an anti-psychotic tranquilizer drug that was calming his gut down which was 41:03 kind of amazing he also had the apoe44 gene so he had some genetics set up for this which is 41:09 the alzheimer's genie he had also genes that affect his b vitamins called methylation and he had a very high 41:14 homocysteine which is an important nutrient marker of folate or b6 or b12 deficiency 41:20 and when he when you look at the data if your level's over 14 you have a 50 increase of alzheimer's he also had 41:28 significant heavy metals and i don't mean to be harping on heavy metals but they they are a big thing in a lot of 41:34 brain damage and they're one of those things that their doctors don't know how to look at they don't have a test they don't diagnose they know how to treat so 41:39 it's really a problem you need to see a functional medicine doctor and he lived in pittsburgh 41:44 and all my patients from pittsburgh are mercury poisoned why because u.s steel is there all the steel plants use coal 41:51 to actually make the steel the coal ash is often used in pittsburgh to cover the roads from ice in the winter to put on 41:58 fields it's in the air pollution and his level was just off the chart plus he had a mouthful of mercury so we we did an 42:04 aggressive medical treatment on him that fixed um his heavy metals that fixed his gut 42:10 that optimized his nutrient status and he also had pre-diabetes so he's a skinny fat guy he looked thin but he actually had this little belly and he 42:16 was pre-diabetic and we got him on a low start sugar diet cured his in some reason so he had b vitamin issues he had 42:22 gut issues he had metal issues he had some resistance pre-diabetes and we fixed all that 42:28 and he went from being completely non-functional to back running his business engaged with his 42:33 family and friends and reversed the cognitive symptoms that he had it was really a miracle and the uh 42:40 the neurologist that i sent him to at at harvard to do all the imaging and the brain scans and stuff that we couldn't 42:45 do was so impressed by the results that he then started a center for brain health 42:51 at harvard so it's you know it's so amazing what you see happen with these patients 42:57 so as you mentioned sometimes a person might need to work with a functional medicine doctor but a lot of times people can take steps and 43:04 head in the right direction just even through a little bit of self-guided and in some cases at home testing so i want 43:10 to talk about testing and are there any tests that are out there you mentioned genetics for example you also mentioned 43:16 uh you know omega-3s and getting more of those in your diet there's like a simple at-home test that people can do we have no affiliation with them that you can 43:23 see they're omega-3s so give a few of these at-home tests and your thoughts in general about 43:28 them and if they can be part of the uh puzzle pieces for people to figure 43:33 out how to get to the root causes that are going on with them well it's interesting i see a lot of companies popping up that are focused on home 43:39 health testing that are focused on giving access to their data for people that are creating companies that are 43:44 allowing people to start to do the diagnostics themselves and be part of a a sort of a self-care process that 43:52 often you know we surrender to our doctors and so there's a lot we can do ourselves 43:58 uh i believe that people should empower their health information they should be empowered with their diagnostic tests they should be just sold your tests are 44:03 okay and they'll see you later and come back next year and they they can actually start to look at some of these things 44:08 um the current landscape of self-testing is limited now but there's things you can do around food sensitivities there's 44:14 things you can do around hormones there's things you can do around around um you know gut testing so there's there's 44:20 stuff that's starting to come out i i don't think we're quite there yet for everybody there's genetic tests like 23andme so people can get a sense of 44:27 what to do um but what would be more exciting for me is some of the companies that are coming out creating 360 44:33 solutions whether doing diagnostic questions they're kind of guiding you in what you should do and how to fix these 44:38 things i think we're not quite there yet but we'll get there and what do you think about continuous glucose monitors and their ability to be 44:45 a pro part of the process of people figuring out what diet is right for them right so before and measure your blood 44:51 sugar you have to go get a blood test with a regular needle or you have a finger stick test which is annoying and painful and you have to machine 44:57 they've developed these new technologies called continuous glucose monitors which are little patches you put on your skin with a tiny 45:04 tiny little needle that goes into the skin there's even more advanced ones coming out that are just going to be like going through your 45:10 skin you don't even have to put a needle in and then measure your sugar continuously and so you can see what's affect your 45:16 blood sugar what's making it spike up and down and you can know oh gee i'm eating this if i eat this if i eat a 45:22 plum my sugar goes crazy but if i had a blueberry it doesn't or if i had this you know meal in this way or that way it 45:29 affects whenever i have a glass of wine before my meal it's way worse than i have it with my meal so you begin to learn about your own biology and what's 45:35 really interesting is that it's not uniform so for example there's something called the glycemic index or glycemic 45:40 load but it really depends on the person right if you look at a study for example down out of israel they looked at the 45:46 same foods on different people and depending on their microbiome their blood sugar levels were quite different 45:52 that's just one variable the microbiome but there's many other variables genetic variables nutritional status variables 45:59 and so forth that are going to affect your metabolism so learning how your body works getting the continuous glucose monitoring as a super helpful 46:07 and personalized way to identify what works for you and what doesn't so i'm a big fan 46:12 let's talk about supplementation there are a lot of companies that are out there that are advertising that this 46:18 supplement is the best thing ever uh for brain health what are actual 46:24 supplements that have a strong evidence base for supporting brain health on top of all the basic lifestyle stuff and 46:30 what are ones that are maybe we should be a little bit skeptical or maybe watch out for when it comes to a category 46:36 so uh they're called supplements not replacements and so if you're eating a 46:42 crappy diet not exercising under tons of stress not sleeping exposed to toxins and your micro bombs a mess you know 46:49 you're going to not really see huge impact and you you you know you have to really look at addressing the factors that are 46:56 causing the imbalance that we talked about and then when you start to put these ingredients in the body can really 47:01 respond right so the most important one is dha for the brain which is docosaccinoic acid it's an omega-3 fat 47:08 comes from fatty fish you get it from algae that would be my number one there are really important cascades 47:15 around b vitamins and detoxification that are important these are genes that affect your metabolism of folate b6 and 47:23 b12 and also glutathione so taking b6 b12 and folate super 47:28 important for the brain magnesium also really important for the brain it helps deal with anxiety it 47:35 helps to stimulate a receptor called the nmda in the brain which calms down 47:40 the sort of overexcitation that happens in the brain that leads to inflammation oxidative stress so 47:46 b vitamin fish oil vitamin d magnesium these are staples 47:52 for the brain so let's go into some questions from our community and starting with the first one what are the top foods for brain 47:59 health so you already mentioned a few but maybe you can expand on this a little bit further and add in some additional ones that you didn't get a 48:04 chance to talk about sure so so the categories are you know omega-3 fats other good fats and 48:10 polyphenols um and there's a whole category of other things that can be helpful so 48:16 in terms of the omega-3 fats the fatty fish is really important we talked about things like olive oil avocados nuts and 48:22 seeds great for the brain walnuts look like a brain kind of a brain food they have good 48:28 omega-3 fat levels also eggs are really amazing so eggs have gotten a bad wrap you want to make sure you have pasture 48:34 raised eggs because those yolks have far more nutrients and polyphenols and and the 48:42 reason they're dark yellow as opposed to this pale yellow that we see in most modern eggs is because of all these 48:48 plant compounds that give it its power it also has choline which is super 48:53 important for the brain because it's one of the neurotransmitters is acetylcholine and you need choline to actually help your brain work properly 48:59 so it's really great in terms of of the brain so i think eggs are a great brain food we also have all the berries they're great because 49:06 they have this class of compounds called proanthocyanidins which are powerful antioxidants anti-inflammatories 49:12 dark green leafy vegetables also really important because of things like vitamin d sorry vitamin k and folate lutein many 49:19 other compounds that are great for the brain and of course turmeric which is a spice that we use a 49:26 lot in the indian cooking but it's it's a wonderful powerful anti-inflammatory that has really been effective for the brain so 49:32 those are some of the top ones i think about uh there's some although other ones that maybe we're thinking about like like green tea which has a lot of 49:39 catechins uh theanine which is calming for the brain so there's a lot of benefits from those 49:45 next question from the community what is the role of coq10 in the brain 49:51 well this is a big rabbit hole so one of the things that people need to understand is that your brain is one of 49:56 the biggest consumers of energy in the brain we've heard the stats that it's you know five percent of your brain about body 50:02 weight or something or maybe less three pounds so that's like a fraction of a percent i guess but it consumes 25 of the energy 50:08 in the body because it's very busy and in each brain cell there are tens of thousands of mitochondria which are the 50:14 energy factories in your cells that you need to actually run your brain and if you have low energy in your brain 50:20 you have alzheimer's you have autism you have parkinson's you have all these things that are really 50:27 an energy deficit so the question is how do you build energy in the brain it's all the things we talked about so 50:33 far but there are certain nutrients that are so critical for reviving and helping the mitochondria 50:38 function better coq10 is one of them but there's many more carnitine coq10 ribose 50:47 enzyl cysteine nad there's a whole cocktail of mitochondrial supplements lipoic acid 50:53 b vitamins niacin riboflavin that are so critical to making energy so think of your energy 50:59 cells as having a a production line where they take food and oxygen and they convert it to energy that your body uses 51:05 that production line has a lot of steps and each step requires nutrients and if you're deficient in any of those 51:10 nutrients you become dysfunctional in terms of making energy which has all these downstream consequences in terms of not just brain 51:18 health but every aspect of your health and aging so taking a cocktail of mitochondrial supplements is really important there's a woman named suzanne 51:24 go who presented grand rounds at cleveland clinic who's a pediatric neurologist trained at harvard oxford brilliant 51:30 woman published in new england journal jam all the top journals and she's done fascinating functional mri studies 51:35 looking at imaging of mitochondria in autistic kids and she found there's a subset of kids 51:41 who have really poor energy metabolism in their brains no wonder they can't connect focus pay 51:48 attention to anything so she gives them a cocktail of mitochondrial supplements and these kids get better 51:55 that's not to say that all kids with autism get better with mitochondrial supplements it's those kids who have that particular pathway and deficit 52:02 right remember i said just because you know the name of what you got doesn't mean you know what's wrong with you if you have autism it just means you have no social skills you may not be 52:10 talking you have repetitive behaviors there's certain descriptions we give to the behavior but we're not talking about 52:15 the cause so uh you know when you see these studies that are these are not even quote functional medicine studies 52:21 this is mainstream medical journals but it's using the principles of functional medicine of how do you create energy 52:27 right so so the the difference between functional medicine and conventional medicine often is conventional medicine's about stopping suppressing 52:33 inhibiting pathways right the anti-drugs antibiotics anti-inflammatories the blockers the beta blockers the calcium 52:39 channel blockers right or we have the inhibitors the ace inhibitors so we inhibit block and anti everything as 52:46 opposed to optimize and enhance function so functional medicine uses compounds that help the body do what it's supposed 52:52 to do naturally which is how do you make energy naturally well you have all these different compounds in your 52:57 diet and the supplements that you can take that help these pathways so when you enhance function there's really no 53:03 side effects it's actually using the natural pathways of the body to optimize your health 53:08 what about the role of caffeine in the brain and the body good bad thoughts okay okay so caffeine well yes 53:16 caffeine gives alertness focus attention but often you get a crash so it creates a temporary 53:22 boost in focus and energy but then it depletes adenosine in the cells which depletes energy and often you'll get a 53:27 crash after so depending on your genetics your ability to metabolize caffeine how fast you are 53:33 how slow you are it's going to affect you differently there are in in coffee and tea other 53:38 compounds so i often say that coffee is sadly the number one source of 53:44 antioxidants in the american diet because americans have such a crappy diet that 53:49 there's no other antioxidants because 70 60 is processed food that doesn't mean that you should be 53:54 drinking a lot of coffee for the antioxidants but it is a source of antioxidants and polyphenols and they may have brain benefits 54:00 so same with tea catechins and other polyphenols in green tea and other teas actually may have beneficial effects on 54:07 inflammation oxidative stress detoxification so they can be very helpful but i think i think over 54:12 caffeinating ourselves is probably not a good idea so let's recap here when it comes to 54:19 improving our brain health and things that we can do today starting today like step 54:24 one two and three what do you wanna share with our audience here as we start to wind down 54:30 today's master class well i think the first thing people understand is that they need to learn how their brain works 54:36 what makes it thrive and what damages their brain and they need to systematically go through their life and 54:41 reduce or eliminate the things that damage their brain and add in the things that help their brain so one of the things what are the worst 54:47 things that damage your brain sugar and starch processed food 54:53 stress lack of exercise lack of sleep those things are fixable 54:58 by anybody without seeing a doctor right and then there are things that the brain needs to function you need 55:05 a lot of good fats a lot of omega-3s you need a diet that's high in polyphenols these 55:11 colorful plant compounds you need a diet that's rich in certain nutrients like magnesium and vitamin d 55:19 and the b vitamins so leafy greens and colorful fruits and vegetables and nuts and seeds 55:24 uh you need to make sure you exercise because that's one of the best things you can do for your brain meditate do yoga make sure you get eight hours sleep 55:30 these are just simple things you can do and there's a much more much more depth about how you can even go down the 55:36 rabbit hole of you know balancing your circadian rhythms and light therapy and various kinds of we call hormetic therapies 55:42 which are therapies that give your body a stress but then it responds by creating a healing response so it could 55:47 be hot and cold plunges it could be you know certain types of exercise there's ways of actually stimulating the 55:52 body to repair and heal then there's even you know more therapies that people can think about for their brain whether it's 55:58 regenerative therapies like ozone exosomes hyperbaric oxygen therapy these are all things that are coming down the 56:04 pike that can be really helpful in repairing and recovering brains but for most people the basics work so well and 56:09 are really things that you don't need a doctor for well you have an entire two-part series 56:16 on brain health i do broken brain one you do and broken brain too and people can sign up for it and watch it it's on 56:21 your website at dr hyman.com and if you sign up for dr hyman plus you get access to that and your longevity docu series 56:29 and a ton of other really great stuff including premium episodes of your podcast so that's a great recommendation 56:34 for where people can go next uh mark this was a fantastic master class and a fantastic breakdown of a topic that so 56:40 many people care about i'll pass it back to you to conclude us for today's episode i think 56:46 you know we we just have to have hope because we're seeing such an epidemic of brain disorders um 56:51 i mean the anxiety and depression is just rampant our society uh and a lot of it's driven 56:56 by our diet we see a dramatic increase in neurodegenerative diseases we see skyrocketing levels of adhd and autism 57:04 and and often people think these are fixed and i just want people to go home thinking that these are solvable 57:09 problems that if we understand how our bodies function we take out the best of putting the good stuff that people can recover from even 57:16 the most challenging conditions there are now survivors of alzheimer's survivors of autism i mean 57:22 never heard of that before so i i want people to leave with hope uh and to understand that they need to focus not 57:28 only on their general health and well-being but to understand how to create a brain healthy lifestyle which 57:33 by the way also fixes everything else what are the top three things that people are doing the root factors that 57:39 are contributing to the chronic inflammation epidemic that we're facing today 57:45 i'm gonna get to those things but first i don't know if people actually know what inflammation is let's go into it 57:51 so people know that if you have a sore throat it's red 57:56 painful swollen and and um that's inflammation and it 58:03 hurts right the the ancient description of inflammation was rubor collar dolor 58:08 and tumor so tumor is swelling rhubarb is redness dolores pain 58:14 and um color is heat right so we have to understand that those are the 58:21 those are the cardinal features of inflammation but then you go well i don't really feel 58:27 inflamed my throat doesn't hurt my joints aren't swollen i don't have a rash 58:32 what do you mean by inflammation it's it's what we call hidden or silent inflammation 58:39 and that is the problem it's the inflammation that we don't see that we can't feel that's causing all 58:45 the chronic diseases that we see today heart disease cancer diabetes alzheimer's depression not to mention 58:52 obviously autoimmune disease allergies and so forth those we know there's inflammation in those but i mean do people think of being overweight is an 58:58 inflammatory state do people think of diabetes as an inflammatory state if you don't think of depression as an inflammatory state no but inflammation 59:06 is causing all of those chronic diseases so back to your question what are the 59:11 biggest drivers of inflammation well it's something that has been only 59:16 recently a phenomenon in traditional medicine and has been ignored pretty much forever except by functional 59:23 medicine which is your gut your microbiome turns out that 60 to 70 percent of your 59:29 immune system is in your gut why is it there well it's the place where you're exposed 59:35 to all the foreign materials every day more than anywhere else the purpose of your immune system is to identify friend 59:41 from foe and to get rid of the bad stuff so when you're eating pounds of a 59:46 foreign material namely food and you have three pounds of form material in there namely bacteria 59:53 that's a lot to handle so the ability of the gut to sense what it should take in to keep out the things 59:59 that shouldn't be in there is so important and so having a healthy microbiome allows us to properly 1:00:06 regulate our immune systems and to let in the nutrients that we need 1:00:11 proteins the amino acids the fatty acids the sugars and carbohydrates that we need the nutrients we need but it keeps 1:00:18 out all the bad stuff it's the first line of defense first line of defense so when that barrier gets broken in the gut 1:00:24 all of a sudden your immune system is exposed to a c [Music] or actually more accurately exposed to a 1:00:30 sewer and and so that starts to piss off your immune system and you start to create systemic 1:00:37 inflammation so the microbiome is is really important and we're just beginning to understand how to identify 1:00:43 what's out of balance in there and how to correct the system traditional medicine is still very much behind the 1:00:49 eight ball in this functional medicine is way ahead by 30 40 years on understanding one how to identify 1:00:55 dysfunction in the gut how to repair a leaky gut how to reduce inflammation how to restore a normal microbiome now 1:01:01 before we go to the other two just to jump in the ancients knew a little bit about this yeah talk about that 1:01:07 uh there's a famous ayurvedic quote that really says if your gut's not healthy you're not healthy and if you 1:01:14 want to fix disease focus on the gut so this has been known for a long time 1:01:19 actually this idea wasn't new eli metchnikoff at the turn of the 1900s was a scientist 1:01:25 who first came up with the notion of the gut as a source of chronic illness 1:01:31 they had some wacky ideas about how to deal with it which was take out your colon which i would recommend 1:01:37 but they were on the right track which is problems in the microbiome in the gut cause systemic disease 1:01:43 and the solution is not cutting out your colon it's mixing the gut but but it was it's not something 1:01:50 that knew and hippocrates says you know health doesn't health and disease starts in the gut absolutely 1:01:57 that was the first one that you wanted to go into what are two other ones that you want to mention and there's a lot of 1:02:02 them that are out there but we're talking about the top three what are two other ones you want to make the other big source of inflammation is our diet 1:02:09 and not any um random thing from our diet but the amount of starch and sugar in our diet 1:02:14 that drives a dysfunction in our metabolism called insulin resistance it's essentially like 1:02:23 where we become resistant to the effects of insulin and our bodies need to make more and more insulin to regulate our 1:02:29 blood sugar and that is because we're flooding our system with pharmacologic doses of starch and sugar about a pound 1:02:34 a day per person which is just historically unprecedented and that insulin resistance 1:02:41 causes the development of specific kinds of fat cells they're called adipocytes 1:02:47 there are specific kind of fat cells in the gut around your belly your belly fat that produce a class of compounds called 1:02:54 adipocytokines cytokines you might have heard about with covate or the cytokine storm 1:03:00 these are the messenger molecules of your immune system and when you have a lot of these belly 1:03:05 fat cells made from eating starch and sugar caused by ends too much insulin and insulin 1:03:11 resistance it creates systemic inflammation so it literally puts your body on fire so if you're overweight 1:03:18 if you have diabetes if you have high blood pressure if you have heart disease if you have dementia these are all 1:03:23 related to this phenomenon of too much starch and sugar and the systemic inflammation we now know that for example if you have 1:03:29 high cholesterol and no inflammation they're very low risk for heart disease but if you have 1:03:35 high cholesterol and high inflammation those are the people who are at risk for heart disease so when you start to look at 1:03:41 inflammation in the body it's not what we can feel but there are ways of measuring 1:03:47 through laboratory testing the amount of inflammation in our body and we're going to become more and more sophisticated 1:03:52 about this david furman at stanford who's a scientist and doctor 1:03:59 developed uh through technologies only recently available big data analytics giant throughput analyses where you can 1:04:05 look at thousands and thousands of blood markers i mean we go to the doctor we get 10 20 lab tests right 30 40 maybe 1:04:12 50. there's thousands of molecules floating around your blood and most of them we completely ignore so he was like 1:04:18 i don't care what we're actually measuring let's look at what actually matters and so he put thousands of these 1:04:24 chemicals through analytic machines correlated with people's clinical history and was able to find four biomarkers of inflammation and immune 1:04:30 dysregulation that are highly predictive of aging highly predictive of heart disease cancer diabetes alzheimer's all 1:04:37 those diseases so we are going to become more and more sophisticated at our ability to look at inflammation people 1:04:43 want to know more about it they can go to edifice i think it's edifice health is the company which is uh actually 1:04:49 commercializing this test but but there's other tests we do like c reactive protein to help to look at inflammation but insulin resistance is a 1:04:56 big driver of inflammation because it makes your belly on fire literally and 1:05:01 these fat cells are just pumping out tons of inflammation throughout your body 1:05:06 the third thing that is really important to understand is that stress is inflammatory chronic stress causes 1:05:13 inflammation in the body through a number of different mechanisms one stress makes you insulin resistant so 1:05:18 it'll contribute to just making you overweight and belly fat even i mean i had a patient once where i this was so 1:05:24 clear she had a daughter who was in israel it was during the time of sort of uh the 1:05:31 infata the uprising a few maybe a few decades ago and she was terrified every 1:05:36 day that her daughter was going to get killed in some kind of bomb or some kind of attack during this palestinian 1:05:41 uprising and so she couldn't she couldn't sleep she was she wasn't even overeating but she just gained all this 1:05:47 weight and as soon as her daughter came back from israel she lost 40 pounds 1:05:52 just like that without changing anything so sometimes stress can be a very big factor in insulin resistance it also um 1:05:59 affects your your inflammatory response and creates an increased inflammatory response so if 1:06:05 and this is interesting if you look at the data on we call sociogenomics which is the ways in which our social 1:06:10 interactions cause changes in gene expression you can be having a conversation with someone 1:06:16 and if they're in conflict with you if you're oppositional if you're having an emotionally charged negative 1:06:24 interaction it will turn on genes of inflammation if you have a loving connected 1:06:29 conversation with someone it will turn on genes that shut off inflammation 1:06:34 so your mind your meal your your brain is the most potent 1:06:40 pharmacy ever and it will drive either inflammation or it will stop inflammation simply by your thoughts so 1:06:47 you have to kind of look at that and and and that's something we haven't talked about a lot is how do we master our minds most of us are victims of our 1:06:54 minds activity and we train our muscles we train our body we increase our metabolism nobody knows how to train 1:07:00 their brain to actually function better from the perspective of being in control of your thoughts and that is that's not an easy 1:07:07 one it's a whole other topic for a podcast how big of a challenge is the topic of 1:07:13 inflammation like really like put it in a sense of a scale in terms of all the things the 1:07:19 world is dealing with when it comes to problems with health how directly tied in is inflammation with those problems 1:07:27 uh is probably the number one driver of all the misery we see in the world uh 1:07:33 there's a beautiful new book that um was written by raj patel and rupa maria 1:07:39 who i've had on the doctor's pharmacy podcast called inflamed and it's about the 1:07:45 the biological the social economic and political consequences of 1:07:51 an environment and a diet that's driven systemic inflammation throughout society 1:07:57 and it's staggering when you start to look at it you know oppression is inflammatory and there's so many people oppressed and struggling 1:08:04 in this society the diet's inflammatory the social structures we have inflammatory and so 1:08:10 inflammation when you look at all the problems that are facing humans um in terms of health 1:08:16 uh it's and even in terms of some of the socio-economic issues that 1:08:21 inflammation is such a big driver and understanding how we calm that down is so so important uh one of the things 1:08:28 that it does which i think is something people don't understand when you look at our society we see 1:08:34 so much conflict so much divisiveness so much hatred so much intolerance 1:08:40 i don't remember it like this growing up i mean i just don't i mean the the diet wars are terrible the 1:08:47 republicans democrats are no longer working together in any meaningful way 1:08:52 um you know we've got religious conflict political conflict 1:08:57 we've got the divisiveness in this country where we had sort of a takeover of the capital 1:09:04 by a whole bunch of people who were you know hopefully making the world a better place but really that was not a very helpful act 1:09:11 so why is that happening well it turns out that uh your brain when it's 1:09:16 inflamed doesn't work and all the things that we see as behavioral disorders 1:09:23 as violence as depression anxiety 1:09:29 mood disorders the opioid crisis turns out that a lot of these things are driven by inflammation in the brain 1:09:35 and and what's happening often is that the inflammatory process diet that we have the changes in our microbiome 1:09:42 because of our diet because of c-sections antibiotics and toxins and all the things that damage microbiome 1:09:47 because of glyphosate all that leads to inflammation and when you have inflammation like that in the 1:09:53 body it disconnects the ancient limbic brain the reptile 1:09:58 brain the fight-or-flight response from the frontal lobe which is basically the adult in the room your executive 1:10:04 function your higher self so when your higher self and your lower self are not talking to each other when 1:10:09 your survival brain and your sort of mature grown up brain that makes sure you don't 1:10:15 do or say or act in ways that are damaging or harmful to other people that connection gets weakened or it 1:10:23 breaks and so when you look at for example diet studies in prisons or in juvenile 1:10:29 detention centers it's so impressive because simply swapping out healthy food 1:10:35 an anti-inflammatory diet for an inflammatory diet in prisons cuts a violent crime by 56 percent he had a 1:10:41 multivitamin by 80 percent in juvenile detention centers these kids are violent 1:10:47 91 reduction in violent behavior 75 reduction demonstrates 100 reduction 1:10:53 suicide rates in this group which is the third leading cause of death in adolescent males and 1:10:59 you reduce it by a hundred percent simply by changing the diet why does it work it works because it 1:11:05 cools off the inflammation in the brain it's causing a disconnect between 1:11:11 people's ability to have executive function to have the grown-up in the room to have 1:11:17 the higher self show up and say gee maybe i shouldn't punch this person or maybe i shouldn't cut them or maybe i 1:11:22 shouldn't shoot them or you know maybe i shouldn't be in this violent oppositional 1:11:28 life and i i think i don't know how much has contributed to the divisiveness in our society 1:11:34 from the food but i i think it's way more than we think and and we've had david promatter and his son 1:11:40 austin on the podcast talking about their book it which describes this phenomena and 1:11:46 the science and the neurology behind the way our diet affects our brain and disconnects our our limbic brain from 1:11:52 our frontal lobe driving violent and disruptive and divisive behavior 1:11:57 well one of the unique things that's happening in today's world that is built on top of all the different 1:12:03 things you're talking about is that there are a lot of people getting rich off of creating this inflammation 1:12:09 we have the food companies that are getting rich by marketing and selling high sugary foods 1:12:16 to the public we have the news media that's literally making incredible 1:12:22 millions of dollars hundreds of millions of dollars by driving inflammatory style news which drives inflammation in people 1:12:28 creates more stress and the advertising is all about inflammatory products right all about inflammatory products food 1:12:37 and many other factors that are out there too so a unique thing that's going on in the 1:12:42 world today that's important to highlight that has really never been there at this 1:12:47 level is that through really the hijacking of media 1:12:53 and the use of media to grow these large companies we now are able to spread 1:12:59 inflammation so rampant and there's a very few and small group of individuals 1:13:05 that are getting dramatically wealthy off the process yes you know i think you know a lot of stuff started off with 1:13:10 good intentions that had bad consequences right in the 1:13:16 post-world war ii era we needed to scale up agriculture to feed a hungry world a growing population to produce a lot of 1:13:23 cheap carbohydrate starchy calories and we did a great job we did a great job the average american has 500 more 1:13:30 calories than they did in 1970 available to them to eat and they're eating it which is why we're all so unhealthy 1:13:36 that was a good idea but the unintended consequences have been devastating not only to human health in terms of 1:13:42 diabetes and obesity i mean when i was born there was a five percent obesity rate now it's 40. it's an eightfold 1:13:49 increase in obesity in my lifetime uh but we've also created 1:13:55 unintended consequences for the environment and and climate and the changes in our in our biodiversity and 1:14:02 loss of species and the damage the soil and our water systems because of how we're growing food so we've created all 1:14:07 these unintended consequences in the same way you know these these food companies were not actually 1:14:13 designing foods to drive all these problems but we're locked in a system where the status quo is trying to be 1:14:20 preserved so they can maintain their market share and their profitability and they're trying to navigate and figure 1:14:25 out how to shift because culture's shifting demand is shifting but you know we we have a 1:14:31 tremendous amount of money that goes into preserving the status quo how we grow food what we grow the processed 1:14:36 food industry the marketing of the food i mean we spend billions of dollars 1:14:41 the food industry gets spent billions of dollars marketing and advertising bad foods and the worst the food the 1:14:46 more money they spend advertising uh and and what's worse is it's it's hidden 1:14:52 advertising now that's really a problem and so these algorithms on the on these um social media drive 1:14:59 you into more and more of the same so if you click on a conspiracy one conspiracy theory you're going to get fed 10 other 1:15:05 conspiracy theories so i met these people that believe in all these weird seemingly disconnected conspiracy theories because that's that's the 1:15:11 universe they live in so we live in these self-reinforcing information bubbles that are driven by algorithms 1:15:17 and the algorithms where they're designed to give people stuff they like to show them if they want a nice pair of 1:15:23 shorts or a bathing suit that they might like again well-intentioned well intentioned but the consequences now we 1:15:28 sort of let the genie out and uh it's out of control and so even the people 1:15:33 who develop these systems i mean i don't think mark zuckerberg is evil or had an evil intent to create more divisiveness 1:15:39 and conflict and disruption in the world and violence no i don't think so but i i also think that 1:15:45 the incentives now are to keep doing it and not to stop so we have to start to look at what we're doing and create 1:15:52 different forms of communications and media and social 1:15:58 media that are not driven off of these algorithms that tend to cause more 1:16:03 disruption more divisiveness and and and are incentivizing the wrong thing i mean one of the things that's 1:16:08 just shocking to me is forget all the ads on tv that kids see and there's about 10 billion dollars spent all that 1:16:14 there's there's 500 billion ads 1:16:19 500 billion ads in one year directed at children for junk food on facebook 1:16:26 that's terrifying to me because the parents don't even know it nobody it's like you can say oh don't watch your tv 1:16:31 kids or don't watch those commercials about you know fruit loops but it's all the hidden 1:16:37 stuff it's all it's all and it's all stealth it's embedded in games there's free games for these kids on social 1:16:42 media and they they play these games but in the games they highlight mcdonald's or highlight coca-cola they highlight 1:16:47 these different kind of food companies that are paying for it and it's it's really co-opting these kids 1:16:53 brains it's copping their their uh their their own free will in a way and i think 1:16:58 that's what scares me more than anything is is they usurping if we will by this digital persuasion economy that's using 1:17:04 algorithms to target us in ways that we that it seems to be things that we like but it actually keeps it spirals out of 1:17:11 control and so we have to get we have to get a way to to solve that whether it's 1:17:16 inventing uh parallel platforms that people can use where where that's not happening in social media platforms or 1:17:22 whether it's it's regulation or legislation this is this has gotten to be quite dangerous it's multifaceted but 1:17:28 most importantly we have to have a dialogue about it and even more important than that is that you the person that's watching the person that's 1:17:35 listening today you have to be the ceo of your health you have to be the ceo of your family's health because ultimately 1:17:42 you know regulation can do a lot but it can only do so much we at the end of the day have to drive education for 1:17:48 ourselves and for our family and that's what this podcast and your work is all about so let's continue down the topic 1:17:53 of inflammation patient comes to you today right what are the signs 1:17:59 and what are the ways that the patient says ouch that are an indication to you 1:18:05 that they have rampant chronic inflammation that is taken over and 1:18:10 hijacked their body it's not that hard 1:18:15 pretty much anybody with any chronic disease inflammation is a player um 1:18:20 and and and so whether you have the typical things that we understand is inflammation like autoimmunity or allergy 1:18:26 or eczema or skin disorders or it's the silent inflammation that's causing heart disease and cancer and diabetes and 1:18:33 obesity and alzheimer's anybody with a chronic condition is typically inflamed at some level 1:18:39 so my job is to then navigate and figure out what's causing it because when you get to the root of inflammation 1:18:47 you don't actually have to treat the diseases directly i don't really treat diabetes i don't treat alzheimer's i don't treat heart 1:18:54 disease i don't treat cancer i simply change the biology of the body to 1:19:00 normalize function to reduce inflammation and as a side effect these things go away 1:19:06 and i think that's a really important concept because if we don't understand that 1:19:11 um root cause medicine is the way we need to go forward then we're going to just be 1:19:18 constantly spinning out on all these new drug treatments and spending billions of dollars to address this i mean they 1:19:24 found oh alzheimer's is an inflammatory disease of the brain so what do you have to do well they did a whole study taking 1:19:30 advil it didn't work and it caused all these side effects why because they didn't get to the root of the inflammation recently a big study came 1:19:37 out on aspirin doctors have been saying take aspirin to reduce inflammation to prevent heart attacks well i've if you 1:19:44 read my stuff over the years i've always said bad idea there are maybe some people who would 1:19:49 benefit but aspirin is not a side effect-free drug and kills as many people as asthma or 1:19:56 aids a year because of bleeding stomach bleeding gastrointestinal bleeding brain bleeding 1:20:01 strokes hemorrhage so the recent study showed that oh sorry guys we were wrong 1:20:06 you can't just take aspen to reduce inflammation and prevent heart attacks because it's going to kill you it's more likely to kill you than the heart attack 1:20:12 so stop taking it which was a huge shocker because if you talk to any cardiologist or talk to any primary care 1:20:19 doctor everybody was on board and i was kind of shocked because i looked at the actual 1:20:24 science that was supporting this and i even look at the american college of cardiology risk calculator there's 1:20:30 actually a calculator on the american college of cardiology website to put in whether or not you 1:20:36 would either get harmed or have benefit from aspirin and most the people who are on aspirin 1:20:41 actually don't even qualify or didn't qualify according to the previous guidelines now there's a whole bunch of 1:20:47 people who who shouldn't even according to those guys let's be taking it so i think that it's backwards to say we're going 1:20:53 to shut off inflammation with anti-inflammatories or immune suppressants i mean they're talking about using drugs like humera which is a 1:21:00 50 000 a year anti-inflammatory drug that's used for autoimmune disease for depression 1:21:06 why because depression is inflammation in the brain the key isn't to shut up inflammation 1:21:12 when the drug is to get rid of the source of inflammation how does traditional and conventional medicine again well-intentioned 1:21:19 how does traditional and conventional medicine look at and treat chronic inflammation like how do they where do 1:21:25 they think it comes from and then how do they decide how to tackle it you know it's just shocking to me that there really isn't a 1:21:31 conversation about why oh we know alzheimer's is inflammatory oh we know depression is inflammatory we 1:21:37 know heart disease inflammatory we know cancer is inflammatory okay so we need to give you anti-inflammatory drugs 1:21:44 there's no questioning of gee why in the first place is your immune system so pissed off 1:21:51 what's creating inflammation and we know so much about it it's not hard it's it's our diet our inflammatory 1:21:58 diet it's stress it's our microbiome issues it's 1:22:03 triggers that for example might be from latent infections or allergens or toxins all these drive inflammation 1:22:10 so as a functional medicine doctor my expertise is in being an expert in understanding toxins 1:22:17 allergens microbes stress and diet because those are the things that drive inflammation and so every individual has 1:22:22 a different cocktail of things that are off but my job is to figure out what is their particular triggers and get rid of 1:22:28 them and then help their body on the other hand calm inflammation down so there's a whole bunch of things that 1:22:34 cause inflammation but there's a lot you can do to reduce inflammation and it's not by taking advil or aspirin 1:22:40 or steroids or some chemo drug or a biologic that costs 50 1:22:46 grand a year it's by the simple things that we know how to do food is medicine anti-inflammatory 1:22:53 exercise is medicine anti-inflammatory sleep is anti-inflammatory meditation's anti-inflammatory yoga is 1:22:59 anti-inflammatory and then there's a whole bunch of supplements you can take to help reduce inflammation like omega-3 fats and vitamin d and probiotics and 1:23:06 zinc and and all the phytochemicals you can eat in your food that actually help reduce inflammation all the spices and 1:23:12 all the colorful fruits and vegetables so there's so much you can do to raise inflammation in the ways that we see now 1:23:19 if you have uh some latent thing right if you have a lot of heavy metals or if you have 1:23:24 a terrible bug in your gut or bacterial overgrowth or you have some particular gluten sensitivity you're gonna have to 1:23:30 deal with those things too but for most people the basics just work so well well let's talk about those basics you 1:23:35 talked about food and you talked about some of the foods that help and we'll chat a little bit more about that but 1:23:41 what are some of the examples of the foods that might hurt what are some of the foods that are out 1:23:47 there that could be driving or at least supporting the process of chronic inflammation and why 1:23:53 do they support that well it's both what we're eating what we're not eating right so we're eating too many inflammatory foods 1:23:59 sixty percent of our diet in america is ultra processed food and what is that talk about the stuff that you see on the 1:24:05 shelf what is an example because you know one thing i've realized and why i want to break this down is that if you go to times square you go here in santa 1:24:11 monica or we're recording and you go up to most people and you say hey do you eat healthy most people are going to say yeah i eat healthy because everybody has 1:24:17 a different definition of what it is or you ask somebody do you eat a lot of processed foods and most most people say no i don't need that much a little bit 1:24:24 here and there so describe it what are we talking about here in ultra processing there are a few commodity crops that are supported by all our 1:24:30 government supports from the farm bill that are the raw materials for processed food corn wheat and soy 1:24:38 and they're turned into all sorts of weird products uh the corn is turned into 1:24:44 all sorts of food additives and high fructose corn syrup the wheat is turned into highly pulverized 1:24:51 flour which is highly inflammatory the oils that come from soybeans and 1:24:56 corn are often highly processed and inflammatory so we're eating a lot of of ingredients 1:25:03 that are derived from these commodity products in ultra processed food that we're not even aware of so when you read 1:25:09 maltodextrin or something on a label you don't know where that came from that's a byproduct of corn from the from a 1:25:15 science project in the factory uh when you eat high fructose corn syrup same thing so we're eating ingredients that 1:25:21 are made from commodity crops they're basically the same three ingredients made into all sizes color 1:25:27 shapes of of chemically extruded food-like substances so 1:25:32 if you actually cover over the packaging and look at the ingredients 1:25:38 you literally would see the same ingredients on almost every processed food we know with a few little tweaks here 1:25:44 and there and you can't actually even tell what it is by reading the ingredient list that's an ultra 1:25:49 processed food if you buy a can of tomatoes and it says tomatoes water and salt you 1:25:55 know what that is if the ingredient list is you know 14 15 35 items um and half of them you 1:26:02 can't pronounce don't recognize they wouldn't have in your medicine cupboard or your kitchen cupboard then you should not eat 1:26:08 them right i mean why should we be eating butylene hydroxytoluene or 1:26:13 or um orthodextrin or all kinds of weird compounds that 1:26:18 are not our natural food supply so those are ultra processed foods and it's a huge component of our diet and it's 1:26:24 highly inflammatory so that's 60 percent of calories on average and when you think of all the 1:26:32 people who don't eat that much processed food and people are eating it might be 70 80 percent right when you average a 1:26:37 lot over all americans it's about 60 and kids it's even worse it's 70 percent 1:26:44 70 for kids i think 67 something it's like terrifying to me so that is really 1:26:49 what we should be focused on not eating that's driving inflammation and sugar and starch is number one two and three 1:26:55 um all the food additives we eat about five pounds of food additives a year and they can be inflammatory for example all 1:27:01 the thickeners emulsifiers things like carrageenan and gums that are used in processed food 1:27:06 they often have something called microbial transflutaminase which is a gluten product that they use to hold the food together and all these emulsifiers 1:27:14 they cause leaky gut so these damage your gut and when you have a damaged gut then guess what the floodgates open 1:27:21 like we talked about earlier in the in the podcast you start getting food proteins and bacteria proteins leaking 1:27:27 into your bloodstream your immune system gets all pissed off and it creates this vicious cycle of inflammation so eliminating all that weird stuff is so 1:27:34 important if you read the label and you don't know actually everything that's on there and you can't pronounce it you 1:27:40 wouldn't have it in your medicine cabinet don't eat it let's talk about next another category 1:27:46 that is directly connected into inflammation and that is sleep and one 1:27:51 of the biggest drivers of sleep that is affecting so many people is sleep apnea 1:27:58 talk about sleep apnea and its direct connection to inflammation for most people and how can increase weight gain 1:28:04 and a whole list of other things that are there it reminds me this guy actually uh sleep apnea is basically where you 1:28:11 where you have multiple episodes of stopping breathing at night so you will 1:28:17 snore you might stop breathing for seconds or minutes your sleep's interrupted 1:28:23 and it's often not diagnosed because you're asleep and you don't know you're doing it your partner might yell at you or 1:28:30 scream at you or move to another room or put in your plugs but you can actually use devices one of 1:28:36 them is a great little app it's called sleep cycle and it just records your sleep on your 1:28:42 phone and you don't need anything it's just you put your phone by your bed and you can have it on airplane mode even and it records your breathing and your 1:28:49 sleep and your snoring and so you can see and hear your snoring from the app so i i know my stepfather was a big 1:28:56 snorer he never believed it he had severe sleep apnea and i literally recorded him with my 1:29:01 cassette recorder back in the 70s because he didn't believe me but you can hear him just snoring like a an elephant 1:29:07 you know so it's really common it's often associated with being overweight 1:29:12 with having a thick neck with um sometimes structural issues a narrow 1:29:18 palate uh various things with your teeth so you can be thin in habit but there may be airway issues uh there can be 1:29:24 central sleep apnea obstructive sleep apnea so it can come from your brain or from your your obstructive airway and 1:29:30 what that does have those repeated awakenings to the night and the decreased quality of sleep it it 1:29:35 actually causes insulin resistance it actually causes diabetes it actually makes you crave more sugar and eat more 1:29:41 sugar and carbs and and you can often fix weight issues or diabetes or obesity unless you fix 1:29:47 sleep apnea and it reminds reminds me of a patient i had when i was at canyon ranch who was a lawyer and he's like 1:29:53 look i can't lose this weight i'm 50 pounds overweight can you help me i'm like okay well talking about your life well i'm a lawyer i'm like okay and 1:29:59 start getting into how do you sleep well okay and i said well i'm tired all the time i said well what it means oh yeah 1:30:04 well i i have to have a stand-up desk this is before stamp desks are possible or i mean we're popular like you know 25 1:30:11 years ago because if i don't if i don't stand up i fall asleep at my desk i'm like 1:30:16 okay well how about we check for sleep apnea and he had terrible sleep apnea we gave him a treatment for it a cpap 1:30:22 machine and he lost 50 pounds like that and his insulin resistance went away simply by sleeping so sleep is so 1:30:29 important in regulating your metabolism and inflammation and you know we think of snoring as kind 1:30:34 of like a funny thing and we might hit our partner or laugh at our parents or grandparent but really as a dear friend 1:30:42 of both of ours uh dr steven lin a dentist down in australia and he says snoring is choking so you have to think 1:30:48 of snoring as choking at night so if you know if you're snoring or anybody else is snoring you're choking and you're 1:30:55 choking and that prevents you from getting the right amount of air and another version of that that's milder is 1:31:00 breathing through your mouth you've done some episodes on this i've done some episodes on this if you're breathing through your mouth at night and not 1:31:05 through your nose which is how we're designed to that's also a sign that you might have a mild form of sleep apnea 1:31:11 that needs to be addressed because it's directly tied into promoting inflammation in the body let's talk 1:31:17 about another category of things that is a driver of inflammation and that's our 1:31:23 sedentary lifestyle talk to us more about that yeah i mean sitting is inflammatory as we sit here 1:31:29 and do our podcast and that's why um so much of us are are struggling is 1:31:35 because when we don't move uh we we are actually increasing 1:31:40 the the poor metabolic function that we have increasing the risk for muscle loss increasing the risk for insulin 1:31:46 resistance increasing risk for just chronic inflammation in our body so 1:31:51 being sedentary is a huge risk for inflammation on the other hand exercising enough but not too much right if you 1:31:58 over exercise if you're ultra marathoner or marathon runner it creates more oxidative stress and inflammation in the 1:32:03 body but if you do regular exercise you literally can reduce the inflammation in your body 1:32:09 and and and that's one of the most important things besides your diet for regulating inflammation 1:32:15 you talked about stress when you sit down with your patients and you talk to them about their 1:32:21 lifestyle what are the biggest contributors that you see over and over again top level 1:32:29 that are the big factors that drive chronic stress individually from patients you know what 1:32:35 is it is the relationship is the lack of meaning and purpose like what are the things that are out there that you see time and time again that are really the 1:32:42 drivers of the stress that everybody's dealing with it's a great question you know why are some people more resilient 1:32:47 than others why does people roll with the punches and others just get completely knocked off center and one of the things we use in our 1:32:54 practice at cleveland clinic and lennox and the ultra wellness center is called the ace questionnaire or adverse 1:32:59 childhood events and it's essentially a set of 10 questions or so that you get a score for 1:33:05 that tracks trauma were you abused as a child were you unsafe just a whole series of questions that 1:33:11 help understand if as a child you experience lack of safety or worse abuse trauma 1:33:17 incest so forth the higher score the more chronic disease risk you 1:33:23 have the more inflammation risk you have the more likely you are to have autoimmune disease to have allergies to 1:33:28 have chronic illness so looking at someone's childhood 1:33:33 is so important and those impacts of trauma and i think we're just beginning to understand how widespread that is and 1:33:41 you know for example one in four americans is a victim of sexual abuse as a child 1:33:46 think about that one in four americans is like 80 million people 1:33:52 that's a lot of people okay um i wonder if that's the 80 million that has autoimmune disease i don't know 1:33:57 but it might be and so as we begin to look at how do we manage the inflammation 1:34:03 response that's the first place i start and then and then i look at how do people 1:34:10 navigate their minds because your mindset plays a huge role in 1:34:15 chronic disease and so if you're able to regulate your thoughts if you're able to not be constantly 1:34:22 triggered and activated by your environment if you're able to have a level of equanimity which can be 1:34:28 cultivated and developed through practice right that's what meditation does and yoga does and prayer does and 1:34:34 there's a whole series of practices of whatever it calls to you that you can do that really helps to reduce the 1:34:41 level of stress in your system if you don't learn how to do those things then you just you just kind of 1:34:47 have this unregulated unmitigated stress response that drives so much chronic disease that keeps you inflamed so yes i 1:34:54 mean we have to one look at the original sources and we have to look at you know how we navigate 1:34:59 our lives and how our our thoughts are and how our relationships are and how our community is and so there are a lot 1:35:06 of ways to work through that and i think it's so important for people to understand that they need to build the structures in their life 1:35:12 that are constantly battling inflammation so what is that for me 1:35:17 it's it's basic practices that i do i meditate every day i exercise i eat an inflammatory diet 1:35:24 i take the supplements that help my gut microbiome stay healthy i make sure i have low levels of toxins that i'm 1:35:29 exposed to i make sure i connect with people i love build community have deep relationships 1:35:35 that's to me what i do to mitigate and to discharge the stress and inflammation 1:35:40 because if you if you don't intentionally do it uh it just accumulates and uh and it's 1:35:46 tough because we we are live in a bubble so it's sort of like being in the truman show we don't even know we're in it and we're just victims of or in the matrix 1:35:52 and we don't know we're in it so how do you get out of that and go okay i'm just going to pause for a minute and kind of 1:35:57 reset and i think that's a really important set of practices that we can all be doing and and it can be fun it 1:36:02 doesn't have to be difficult or stressful one of my favorite is is hot and cold therapies so sauna steam ice 1:36:09 plunge it's amazing for discharging stress literally your whole system will will sort of reset i remember 1:36:16 working in uh residency and you know we had an enlightened residency where we only had to work 30 hours in a row not 36 hours 1:36:25 i would get off noon the day after call and i'd drive up to this hot springs in california and i would soak in the hot 1:36:30 springs and then i would go in the ice pool and the hospital was super hot and icing was super cold and it'll go back 1:36:36 and forth back and forth and i just know all my fatigue all my stress from working on the hospital and the call and 1:36:42 the trauma just would go away and i would like reset and you know now it's a thing but 1:36:48 back then we just kind of was weird but it's so powerful so you have to learn for yourself one of those things that you can incorporate that you like into 1:36:54 your life on a daily basis that help regulate you let's go back to the gut microbiome you 1:36:59 listed it as one of the top things that a disrupted gut microbiome 1:37:04 or a dysregulated gut microbiome is one of the key drivers of inflammation 1:37:10 you have in your lifetime on multiple occasions had a gut that's been messed up right we won't get into the whole 1:37:15 journey we made a couple documentaries about it if people want to watch them they're at drhymen.com 1:37:20 sign up for a free trial you can watch them broken brain longevity docuseries we've talked about them all yeah but 1:37:26 high level what was missing for you when your gut 1:37:31 was dysregulated and how did you begin to take the steps to bring it back into repair 1:37:37 i mean i you know i didn't have the usual things i was always a weirdo so for me 1:37:44 um the first time was mercury poisoning and mercury is 1:37:50 powerfully damaging to the gut it will bind to all the enzymes it'll cause leaky gut and it creates bad bugs 1:37:56 growing and yeast overgrowth so for me i developed you know chronic diarrhea 1:38:02 bloating irritable bowel bacterial overgrowth fungal overgrowth 1:38:08 and and that was really really really hard to treat until i got the mercury down that was my first foray into bad 1:38:14 gut then i kind of corrected it after i got the mercury out and rebuilt my gut and then about five years ago 1:38:21 i had a bad tooth and ended up having a root canal the root canal went bad got the tooth 1:38:27 pulled and the dentist who was a holistic dentist said you better take this antibiotic 1:38:32 and i'm like okay and i just was a little nervous about it and it's a particular antibiotic that's great for dental infections called 1:38:39 clindamycin but it's also the biggest cause of what we call c difficile which is a terrible 1:38:46 intestinal infection that kills 30 000 people a year very difficult to treat and they're 1:38:51 using fecal transplants to treat it almost 100 percent cure and the typical antibiotics that are 1:38:56 used don't work that well so i basically developed c difficile which was a terrible intestinal infection colitis 1:39:03 and that caused colitis and then that developed into inflammatory bowel disease i was having 20 bloody bowel 1:39:08 movements a day severe pain i mean it was just i lost 30 pounds it was it was 1:39:13 bad and all my normal tricks didn't work why because my whole system was so 1:39:18 screwed up by the mold in my house and by this infection that took over 1:39:25 that even even taking prednisone didn't work and i was you know next step was taking a biologic and i didn't want to 1:39:30 do that and so i began to sort of figure out how do i really 1:39:36 reset my system and sometimes you just need a powerful set of tools 1:39:41 to drive the body out of a stuck inflammatory cycle and i based on my experience in the 1:39:47 science and what i understood i use a combination of things that just const just almost immediately flipped my 1:39:52 system one was ozone therapy that was hyperbaric oxygen therapy i use high-dose intravenous vitamins and 1:40:00 vitamin c and also stem cells and those four things and exosomes those four things really 1:40:07 flip my system out of this stuck inflammatory cycle but that was weird and that's rare and most people i don't 1:40:13 need to do that with but i'm a weirdo so i i get all the worst of everything and then i have to figure it out and then i 1:40:18 you know kind of learn how to sort of make my body work better well one of the unique things that came 1:40:23 out of that is that once you got your system back to baseline and it was really bad right it was really bad we've 1:40:28 talked about that before but once you got it back to baseline you went down this whole rabbit hole of how 1:40:33 the power of phytochemicals as you talked about earlier phytonutrients phytochemicals these plant compounds 1:40:39 uh on a regular basis can help you maintain this level of where you're at so talk to us about it yeah so how is 1:40:45 this that food is really information in this category of phytochemicals yeah so so for decades we've known that 1:40:52 prebiotic fibers are healthy and prebiotic foods are healthy what is a prebiotic it's something that feeds the 1:40:57 good bacteria so it could be various kinds of fibers that are in plant foods special foods like artichokes asparagus 1:41:04 plantains jerusalem artichokes all have these special fibers that are 1:41:11 really good food for the microbiome also the probiotics are important to probiotics 1:41:16 and there's all kinds of strains we also knew that that um that that we need to make sure we have 1:41:23 the the right amount of of of just general fiber as well so those are those are things we understood 1:41:29 but what i didn't understand was the importance of the phytochemicals in food to feed the good 1:41:37 bugs because not only do they eat the fiber but they also are stimulated and love certain phytochemicals for example 1:41:44 there's a really important bacteria that i had almost none of which is called acromancia mucinophilia mucinophilia 1:41:50 means mucin loving right mucin is mucus why do you have that well you want to 1:41:56 protect your intestinal lining and not get a leaky gut so your back this bacteria creates this incredible thick 1:42:03 mucous layer that prevents bad stuff from getting in but if you don't have this bacteria you can't get that well 1:42:10 when i had this problem you couldn't actually take a necromancy or probiotic now they have them 1:42:15 but acromancial love polyphenols which are these colorful 1:42:21 compounds in fruits and vegetables they love cranberry they love pomegranate they love green tea they love curcumin they have all these 1:42:27 incredible plant compounds and so that was a huge insight so we need prebiotics probiotics 1:42:33 and polyphenols to create a healthy gut which is why eating a colorful 1:42:38 diet is so important beautiful and you've written about akromancia we'll link to the blog post 1:42:45 that you have there you even talk a little bit about this kind of shake which includes uh pomegranate concentrate and a bunch of other things 1:42:51 green tea cranberry and green tea so we'll link to that as well that really helped me by the way that really helped me reset my gut i created this cocktail 1:42:57 of stuff that was designed to incorporate all the knowledge that i had over 30 years of functional medicine it 1:43:04 was a lot of different things in little containers and things we've now created something called gut food which will 1:43:09 soon be available on getpharmacy.com which combines all these things into one simple powder that you can mix in water 1:43:16 or in something else and actually consume it and it will help to provide the food for your gut we're calling it 1:43:22 gut food let's talk about testing when it comes to inflammation are there tests that you use and 1:43:29 recommend both with patients that you work with but also if people don't have access to a functional medicine doctor 1:43:34 are there tests that you recommend they ask their doctor for to help them 1:43:40 understand how inflamed they are yeah i mean there's two aspects to this one is checking for inflammation to see if 1:43:46 you're inflamed and then checking for why you have inflammation two different things so why your 1:43:52 inflammation may be imbalances in your gut flora it may be toxins it may be allergens it may be your diet it may be 1:43:58 stress right so we have to go down those rabbit holes in terms of the actual measure of inflammation 1:44:03 we're getting much more sophisticated about it so there's a common test that your doctor can do called c-reactive 1:44:08 protein and that's really important has to be a high sensitivity c-reactive protein that can help you determine if there's a 1:44:14 generalized level of inflammation it's good but it's not perfect then there's a sedimentation rate which is an 1:44:20 age-old test it looks at how long it takes your blood to settle if it's got a lot of inflammatory proteins it's done and settled in the test tube very fast 1:44:26 that can be a sign so there's there's common things we use we can also look at cytokines we can look at interleukins 1:44:32 and and we can look at two necrosis factor alpha and other biomarkers of inflammation 1:44:37 but that's just scratching the surface there's a whole as i mentioned earlier there's this scientist at stanford who's 1:44:43 measured these unique analytes in your blood that doctors 1:44:48 normally don't test that are the most predictive of aging and chronic disease so we should probably be testing things 1:44:54 like that so those are the ways we kind of measure inflammation we can also look at auto antibodies we can look at 1:45:00 allergens we can look at immunoglobulin levels there's a lot of ways we can look at what's going on with the immune system we look at t cell function and 1:45:06 lots of things so the basic tests are available through conventional medicine but the key is not just seeing if you're 1:45:12 inflamed the key is to ask why you're inflamed and then go down the rabbit holes of looking for the causes 1:45:19 can you share a case study from your practice of anybody because we have so 1:45:24 many different names for modern diseases that are driven by inflammation but if you can think of one person who 1:45:30 had the right mixture of a lot of different root factors that you helped and worked with to get their 1:45:35 inflammation under control and then get back to health 1:45:41 absolutely just think of so many patients that are flooding my brain right now but i'll just share one story 1:45:46 of a woman with rheumatoid arthritis terrible migraines 1:45:52 and a lot of gut issues and you know typically she was seeing her 1:45:58 rheumatologist and getting all the rheumatology drugs and really struggling and so i said well okay these are all 1:46:04 inflammatory problems migraines gut issues rheumatoid arthritis let's look and see what's causing it so it turned 1:46:09 out she had very high antibodies to gluten so she was gluten sensitive and quite significantly she had 1:46:16 bacterial overgrowth in her gut and she had super heavy metals so systematically i got gluten out of 1:46:21 her diet i healed her gut i got rid of the heavy metals and 1:46:28 she had complete recovery and all the things that were abnormal her c-reactive protein her rheumatoid arthritis 1:46:34 antibodies her my her migraines her her leaky gut all normalized and now it's 20 years 1:46:40 later and she's still amazing and got rid of all those diagnoses because 1:46:46 they were all caused by inflammation you talked about diet you talked about additional therapies like sauna hot and 1:46:52 cold other things like that we talked about exercise talk about supplementation how does it play a role 1:46:59 and how could it be helpful on the topic of inflammation well you know just the most basic things can be helpful right so there was a study 1:47:06 published that showed that if you take a multivitamin your c-reactive protein level goes down which is awesome but 1:47:11 that's just one thing and and what is the mechanism of that that you think yeah so we we have a system in our body 1:47:17 to control inflammation and that system requires nutrients and many of us are nutrient depleted so for example a 1:47:23 multivitamin will reduce c-reactive protein and it does so by activating all sorts of enzymes cool so vitamin what 1:47:29 are vitamins minerals they're basically helpers one-third of your entire dna codes for enzymes what enzymes do they 1:47:35 turn one molecule to another molecule one chemical to another chemical in your body and all the enzymes we nee we have 1:47:41 required coenzymes or cofactors helpers and what are those those are vitamins and minerals and so 1:47:48 some of us need a lot more of this one or that one and if we're low which a lot of us are this is not my opinion this is the 1:47:55 government's own surveys and diagnostic testing and giant studies of tens and tens of thousands of people that over 90 1:48:02 percent of americans are deficient in one or more nutrients at the minimum level you need to prevent deficiency 1:48:08 disease so not how much you need for optimal health or immune function but how much vitamin d do you need to not 1:48:14 get scurvy i mean to not get rickets not very much how much vitamin c do you need to not get scurvy not very much but how 1:48:20 much vitamin c or vitamin d to regulate your immune system and reduce inflammation a lot more 1:48:26 so many of us are deficient in nutrients so that's the mechanism and then there's specific nutrients that are really 1:48:31 important inflammation omega-3 fats number one we need the omega-3 fats like ep and dj 1:48:38 that typically come from fish oil we need the vitamin d levels to be adequate 1:48:45 and and not low because vitamin d regulates hundreds of genes that regulate inflammation 1:48:51 we need to make sure we have adequate amounts of things that help to boost detoxifying 1:48:58 compounds in our body like glutathione which comes from the for example broccoli family when you 1:49:03 eat these compounds they help to increase glutathione but also you can take for supplements to do that like n-acetyl cysteine which i think the 1:49:10 government is is now restricting in some ways which makes me very nervous but this is a substance we've used for 1:49:15 you know a long time decades and decades since i've been in medical school and medicine as a therapy to 1:49:21 help recover people from tolerant overdose and liver failure from kidney failure from dye contrast and many other 1:49:27 things so for asthma and lung inflammation so it's one of the most powerful anti-inflammatories in our body so i take supplements to increase 1:49:34 glutathione which really helps so there's a there's a few things we can do strategically and then of course there's things like curcumin and there's 1:49:40 polyphenol supplements and and various other things you can take but but those are the most important talk to us about 1:49:45 the role that fasting plays fasting in all its different forms when it comes to 1:49:52 chronic inflammation that plagues so many people so our bodies 1:49:57 were designed to deal with scarcity and we have hundreds of genes that help control 1:50:03 starvation and put our bodies in a healing and repair state when we are 1:50:11 lacking food we have almost no genes that help us deal with abundance in excess like the 1:50:17 500 extra calories of corn syrup that every american is exposed to since 1970. 1:50:23 so when we are in a state of scarcity our bodies kick into action a whole set of 1:50:29 mechanisms that reduce inflammation that increase antioxidant systems that build muscle that get rid of fat 1:50:36 burn fat which is good in the case of starvation and that help to increase stem cell function 1:50:42 and and many many other beneficial factors improve mitochondrial health clean up your cells get rid of waste i 1:50:47 mean it's just it's quite amazing what happens when you have scarcity when you starve which is a good thing because you 1:50:53 you want to keep alive as long as possible so everything is in your body is like i'm just going to fix everything so i don't die 1:51:01 so how do you get to that state well there's a lot of techniques that are now being talked about and they all have the same mechanisms whether it's 1:51:08 time-restricted eating which is eating within an eight-hour 10-hour 12-hour window whether it's intermittent fasting 1:51:13 which is having a 24-32 hour fast once a week or more prolonged fast whether it's 1:51:18 fasting making diets which are calorie restricted diets for five days of 800 calories whether it's a ketogenic diet 1:51:25 which restricts carbs and increases fat that's actually what we get in when 1:51:30 we're not eating we get in a ketogenic diet when we don't have food our bodies go in ketosis but you can do that by 1:51:35 eating more fat so all those ways of eating actually activate the body's own healing 1:51:41 mechanism and what happens well you reduce inflammation you increase antioxidant systems you increase stem cell production you increase muscle you 1:51:48 increase bone density you increase cognitive function and brain chemistry and neuroplasticity 1:51:53 you do all these things simply by activating these ancient healing systems that are designed to protect us from 1:52:00 starvation so it's kind of like controlled starvation in a way and that's a good thing and i think it's 1:52:06 really it's really important for us to think about how we do those things on a regular basis and i try to incorporate those strategies regularly in my life 1:52:14 so now we're going to go to our community our youtube comments our facebook comments instagram and podcast 1:52:20 community that emailed in we're gonna take a few questions here and we're gonna start off with the first one and 1:52:26 the first one we have here is what role do grains play when it comes to 1:52:31 inflammation chronic inflammation in the body can grains help or hurt chronic 1:52:36 inflammations in the body great question depends on the grain white flour surely is one of the most 1:52:42 inflammatory foods on the planet whereas ancient grains like himalayan tartary buckwheat may be one of the most 1:52:48 anti-inflammatory foods on the planet so it's not grains as a whole it's which 1:52:54 grains in what form how are they grown where were they grown what were they grown with are they full of pesticides 1:52:59 are they full of glyphosate i mean there's there's so many layers of things that will actually determine the answer to that question 1:53:05 in general though the way we eat grains in this country is as white flour 1:53:11 90 of the grains we eat in this country is white flour very few people eat whole grain foods um 1:53:17 maybe there's a whole wheat bread but if you look at the label it's mostly white flour with high fructose corn 1:53:23 syrup with a few flakes of whole wheat thrown in there right it's not it's not like the dense breads you get in europe 1:53:28 or germany so i i'm not against grains but i do think that there are are challenges for people who are a lot 1:53:35 eaten a lot of flowers probably one of the most inflammatory foods and if you have a leaky gut if you have 1:53:41 an imbalance in your microbiome if you're not having an intact system in your gut 1:53:46 it grains can be a problem so i tend to eliminate grains if i'm really aggressively trying to reduce 1:53:52 inflammation not forever but for a short period of time to try to reset the system to heal the leaky gut and get 1:53:58 people functional again and if you if you if you do that you you also do a 1:54:03 number of other things because grains are starch and depend on how much you eat right having a half a cup of black 1:54:08 rice or a half a cup of buckwheat may not be a problem but typically we 1:54:13 eat huge amounts of grains and that drives another pathway for inflammation which is insulin resistance 1:54:20 or pre-diabetes or blood sugar problems and so we we have to understand that we have to reduce the starch and sugar in 1:54:26 our diet and one way that is is actually reducing grains but whole grains can be a part of a healthy diet it's just 1:54:32 when you get to eat them who gets to eat them in what contacts with what other foods and where those grains come from 1:54:38 and are they you know modern hybridized grains that are full of starch and sugar or are they 1:54:43 ancient grains that have all these phytochemicals and other beneficial properties 1:54:49 next question how does hormonal balance or imbalance related to inflammation 1:54:56 so the biggest driver of chronic inflammation is stress which 1:55:01 drives all kinds of hormonal dysregular regulation it screws up your hormones the sex hormones your insulin 1:55:08 blood sugar uh cortisol adrenaline and and that really drives huge amounts of 1:55:13 inflammation so if if you are actually are are highly stressed that will drive a 1:55:18 lot of the pathology i mean insulin is another hormone that is a big one that drives inflammation that's one of the biggest ones we talked a lot about that 1:55:25 you'll see people who are taking hormones for example estrogen or the birth control pill 1:55:31 and and depends on what you're taking if you're taking for example premarin it raises inflammation in the body it 1:55:36 causes a high crp so does the birth control pill so a lot of people are taking the birth 1:55:42 control pill i'm not saying people should stop birth control uphill but you want to make sure you mitigate the effects of that and 1:55:48 recently did an instagram live with the founder of eben sarah morgan talking about the ways in 1:55:54 which for example medications deplete nutrients and affect the body adversely so for 1:56:01 example if you're on the pill the birth control pill you may need to take certain nutrients to mitigate the effects of that and help reduce 1:56:06 inflammation so certain things i would never take like premarin which is a hormone that drives inflammation but i i 1:56:12 certainly wouldn't tell everybody to stop the birth control pale but i think you have to know what you're doing and actually offset the harm by taking the 1:56:19 right nutrients to actually mitigate the damage and the inflammation that comes from that last question here before we 1:56:24 go into final thoughts and conclusions can inflammation be tied to our 1:56:30 genetics are some people more prone to developing markers of inflammation 1:56:35 especially chronic inflammation absolutely i mean we're all heterogeneous you know we 1:56:41 have twenty thousand genes we have about five million variations in those genes and some of those variations predispose to inflammation and we test those i do 1:56:48 that in my actual practice looking at saliva 1:56:54 swabs that measure dna and we can look for variations in certain genes that affect 1:56:59 the cytokines like interleukins and cnf alphas other genes and we can see oh 1:57:04 you're someone who if you get some trigger is way more likely to be inflamed 1:57:10 so there are people who are predisposed inflammation but that doesn't mean they're predestined to inflammation 1:57:17 so they need to identify one the sources of inflammation in their life and get rid of them we talked about those and 1:57:23 they need to include anti-inflammatory strategies in their life an anti-inflammatory diet more polyphenols 1:57:29 probiotics antioxidants and obviously other anti-inflammatory strategies like 1:57:34 adequate sleep and exercise and stress reduction so forth so hot and cold therapies we just need to up regulate 1:57:40 the anti-inflammatory system and calm down the inflammatory system so yes there are people who are genetically predisposed but it doesn't mean they're 1:57:47 predestined so not everybody will have access to a functional medicine doctor obviously if they do that's fantastic and amazing you 1:57:53 can go to ifm.org and find somebody in your area it is often expensive insurance doesn't 1:58:00 cover it but it's and it's not available to everybody but if you can it's a great thing if you can't and for example they 1:58:05 wanted to explore the topic of genetics a lot of people have 23andme data are there any of those websites that you 1:58:12 like or would recommend to people that they can plug in their raw data and get back some of these 1:58:17 unique markers that they have to pay attention for their own genetics i mean there are uh is a genetic genie 1:58:25 which is sort of a interpretive guide where you can plug in your 23 meat data which can be helpful for looking for 1:58:30 problems with methylation and glutathione and detoxification and some of the inflammation genes 1:58:35 23andme only does a small slice of your genome it doesn't look at everything so we do 1:58:41 more clinical testing uh and i tend to do that and focus on that so there may be there's so much going on right now in 1:58:47 the space i may not be familiar with it but there probably are companies that are looking at inflammatory genes that are 1:58:52 available to consumers the question is when you do that information and i think that's the challenge for people how do you change your diet what supplements 1:58:58 you take what do you avoid i mean it gets a little granular so it's usually better to work with someone who is 1:59:03 experienced to understand these tests how to mitigate your risk and to to create a lifestyle 1:59:09 that actually helps to reduce inflammation hey youtube if you enjoyed what you just saw keep watching for more 1:59:14 great content on how to improve your brain and your life if you give a plant too much water it drowns 1:59:21 if we have too much glucose in our body bad stuff starts happening we start 1:59:26 seeing consequences and specifically if you eat a meal that These FOODS & HABITS Boost Brain Health & REDUCE INFLAMMATION | Mark Hyman Dhru Purohit 434K subscribers 398,468 views Apr 28, 2022 If you haven’t heard, me and Dr. Mark Hyman have been teaming up to do weekly podcast episodes called “Masterclasses.” We sit down and have deep conversations about the most important health topics of our time and give you all the answers you’ve been after. This week on The Dhru Purohit Podcast, I am featuring two of our favorite Masterclass episodes all about creating optimal brain health and reducing inflammation. We talk about the top foods to avoid—and to enjoy—to optimize brain health, why sugar is so bad for the brain, and how toxins can lead to neurodegeneration. Then we break down the meaning and function of inflammation and how it manifests as heart disease, cancer, diabetes, depression, and more. Dr. Mark Hyman is a practicing family physician and an internationally recognized leader, speaker, educator, and advocate in the field of Functional Medicine. He is the founder and director of The UltraWellness Center, Senior Advisor for the Cleveland Clinic Center for Functional Medicine, a fourteen-time New York Times bestselling author, and Board President for Clinical Affairs for The Institute for Functional Medicine. He is the host of one of the leading health podcasts, The Doctor’s Farmacy. Dr. Hyman is a regular medical contributor to several television shows and networks, including CBS This Morning, Today, Good Morning America, The View, and CNN. He is also an advisor and guest cohost on The Dr. Oz Show. This episode is brought to you by Pendulum: https://pendulumlife.com/ Cozy Earth: https://cozyearth.com/ Pendulum is the first company to figure out how to harness the amazing benefits of Akkermansia in a probiotic capsule. To receive 20% off your first purchase of Pendulum’s Akkermansia probiotic supplement, go to https://www.Pendulumlife.com and use code DHRU20. Cozy Earth are the most comfortable, temperature-regulating, nontoxic sheets on the market. Right now, get 40% off your Cozy Earth sheets. Just head over to https://www.cozyearth.com and use code DHRU. Social & Website Instagram: https://www.instagram.com/dhrupurohit... 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Show transcript Dhru Purohit 434K subscribers Videos About 1:40:11 #1 Neuroscientist: Truth About Laziness, Discipline, Exercise,Stress & Journaling | Andrew Huberman by Dhru Purohit 1:39:34 How Insulin Resistance DESTROYS Your Brain & Causes ALZHEIMER'S / DEMENTIA! | Ben Bikman by Dhru Purohit 1:52:39 The 4 Secrets to AGE IN REVERSE & Live Longer TODAY! | Dave Asprey & Dhru Purohit by Dhru Purohit 1:50:11 Jason Fung & William Li REVEAL The 4 Steps to PREVENT DISEASE! by Dhru Purohit 373 Comments rongmaw lin Add a comment... @DhruPurohit Pinned by Dhru Purohit @DhruPurohit 1 year ago Get my FREE guide Raise Your Omega 3's when you sign up for my weekly health newsletter at dhrupurohit.com/omega3 36 Reply 12 replies @lawrencecheng5677 @lawrencecheng5677 3 months ago I was born in Hong Kong and am 65 years old. At the age of 60 when I retired, I was nearly 200 lbs (with a height of only 5' 5")! Accompanied with Atrial Fibrillation, very high blood pressure and liver inflammation, I had been very dependent on medical prescriptions since 50 years old. You can imagine my health status. I began to learn on the Internet after retirement and started intermittent fasting (16/8), drinking black coffee, extra virgin coconut oil and even MCT oil (in order to alleviate hungry feeling). I usually skip breakfast with only 2 boiled eggs and bullet proof coffee as my lunch. Within a fortnight, it began to bear fruit. I obviously lose weight at an average rate of 2 lbs every week. I occasionally adopted 20/4 IF. The result was even more amazing. In one year's time, I shred almost 80 lbs. Together with the help of daily intake of MCT oil, black coffee, brisk walking, light dumbell exercise and being vegan, I feel great again. 63 Reply 1 reply @ladyc3205 @ladyc3205 6 months ago This is an outstanding interview. I’ve been looking at many health related videos for help to get rid of excessive weight and inflammation in my body. This explains so much on the value on eating simple and real food and insulin resistance on the body. I worked around researchers and doctors most of my adult life and not once did any of them ask about what I was eating. Functional medicine is a game changer. I’m grateful and thankful for this video and sharing with family and friends.💯 29 Reply @kellio8087 @kellio8087 1 month ago Choosing an anti-inflammatory diet and supplementing, healed my chronic inflammation, hypertension, muscle cramps, muscle spasms, and twitches and gut issues. Based on my experience, Dr Hyman's spot on! 5 Reply 1 reply @barbarailarpenter6815 @barbarailarpenter6815 7 months ago To the nurse who wrote about alcohol: Thank you!! And being a nurse is something to be proud of! It is a big deal to the person who made a smart remark. Be kind, everyone. You don't have much time on this earth, and no one likes a jerk. 63 Reply 2 replies @VK-vd8qz @VK-vd8qz 1 year ago (edited) Dr Mark you are like a General Hospital.Your have explained all the problems i am facing now step by step and very clearly. Lately i realised the root cause of my problems but your explanation is very very clear. I dont think so any paid specialist will explain this deeply. I felt my organs were dropping one by one 2 yrs ago and still struggling. Now, i understand how bad is inflamation to rhe body. Your video is quite long but it is not boring because each words and sentences are very useful and important..Thank you very much and please post more videos. Dhru Purojit i have subscribed you channel. Keep it up. 33 Reply @theantiqueactionfigure @theantiqueactionfigure 6 months ago (edited) Mark Hyman's medical situation was nearly identical to mine, although I'm a long way from recovery at this point. I feel that my through the roof lead levels and elevated mercury were the root cause of my Chronic Fatuge Syndrome which began about twenty years ago. This podcast is motivating to get my chelation therapy restarted. Just not looking forward to the Herxheimer that it always put me through. 8 Reply @myrnaleon8464 @myrnaleon8464 2 months ago Another excellent, comprehensive video from Dhru. Thanks for featuring Dr. Hyman in this series. 😊❤ 7 Reply @debbiefarrar7356 @debbiefarrar7356 7 months ago Thanks so much to you both so interesting Listening to this and other podcasts are helping me heal after a stressful life and a stroke Now lm on a better journey learning all the best foods & exercising and learning not to stress is helping As they say stress kills and my stroke was a wake up call. Walk away from toxic partner and toxic people. I was bought up by toxic mother and didn’t know any different Also childhood trauma and lots of awful things happened sexual abuse And marriage of domestic violence Now lm 60yrs old and turning my life around 33 Reply 2 replies @user-dv2rj6gx7m @user-dv2rj6gx7m 3 months ago Thank you for giving all information to people, I am Austrian, and we dont eat processed food, maybe only sometimes. Our food should be organic grown without pesticids and fertilizer. We cook every day fresh and enjoy our meals sitting around table with our familymembers. 19 Reply @wmalinowymstylu7670 @wmalinowymstylu7670 5 months ago I haven't eaten sugar since 2018, and I feel totally different. The bitter fruits or veggies don't have this strong bitterness. Bitter herbs like wormwood are not so bitter like 5 years ago when I started drinking. My brain is really working differently, faster, better concentrated, I see colors clearer and intense, I'm not stressed anymore, no panic attacks, less stomach problems etc etc....I have thought out from my diet gluten and lactose. No more unexpected diarrhea in my life 😆. Of course, I'm still taking other supplements, but the good one, and I feel amazing. People, please open up your eyes🙏Wake up! Life without white sugar is more beautiful. And who has donn it knows what about I'm speaking 😊God Bless u all, Monika 16 Reply 3 replies @victorallicock3154 @victorallicock3154 6 months ago Thanks for you guys for a very informative and well presented interview. I am hooked on this video and will put this info, into action immediately. God bless you both. 6 Reply @ekiggai3805 @ekiggai3805 1 year ago Dr Mark, thank you so much for sharing this priceless information. Thank you Dhru for organising this podcast.. I am using this inf. helping someone in trouble. 28 Reply @mariaolsen39 @mariaolsen39 1 month ago Thank you for all this valuable information and the time you give to educate people. I am grateful to you both for these wonderful chats. Unfortunately, Continuous glucose monitors are not an option in my country. They cost a small fortune in continuous fees, and you have to be a diabetic to get one. One day they will become more accessible to everyone. Reply @cassondrad2280 @cassondrad2280 1 year ago (edited) Thank you. It comes down to the "root cause" of inflammation, childhood trauma, what are you feeding your body, sleep, stress, relaxation. Thanks 17 Reply 1 reply @19squidgy75 @19squidgy75 5 months ago This resonates at with me completely, every single word he speaks is 100% true. My breakdown started on 13/1/2020, I am slowly digging myself out of this hole 🕳️ 3 Reply @kathycole1 @kathycole1 1 year ago Highly intelligent! It is so amazing to see healthy results through clean eating. Thank you for your wisdom. 11 Reply @RichardAlsenz @RichardAlsenz 1 year ago I am a theoretical physicist, not a medical doctor. I enjoyed this discussion very much. I am concerned that the issue of viscosity in body fluids is not considered in discussions of inflammation. Acidic production within the body reduces the flow of body fluids. The lack of oxygen in the body fluids seems to be a significant obstruction to the healthy flow of body fluids due to this inflammatory viscosity reduction. Microbial byproducts appear to be the primary producers of acids and seem to be the most likely sources of inflammation. Inflammation seems to have many health benefits, yet it also appears to be a significant heath problem generator. Otto Warburg spent a significant amount of his life on this effect within the cell membrane, yet the issue is more relevant outside of the cell membrane. For the oxygen to support cell reproduction, it must get to and within the membrane. I would be very interested in hearing your comments on this subject. 14 Reply @sazennonumber @sazennonumber 5 months ago This was great, thank you. Even if some listeners have heard of all of the mentioned recommendations, it is well rounded up, super-inspiring and helpful. 2 Reply @kathycaruso1587 @kathycaruso1587 1 year ago Great information, you give the average person tools and power to improve their health and lives! 16 Reply @jmisati69 @jmisati69 1 year ago JOSEPH OGATO MISATI .Dr Heyman has been a gift to humanity;indeed a God given gift.A turnaround in the medical field.Such information can help reduce our visits to conventional doctors.I am an ardent follower to his lectures/expositions.I am a 59 year old Kenyan teacher who is reaping enormously from YouTube. A couple of years added to my lifespan!May our Almighty add more and more years to Dr Heyman. 12 Reply @ccog6450 @ccog6450 7 months ago I had the exact same symptoms and had an EMG to r/o ALS. I was told my sx’s were stress related. It was a year or so of worry and stress. 4 Reply @parisconstantinou8299 @parisconstantinou8299 1 month ago Great work like always Guys!!!as one of the historical pioneers in the field of Natural Medicine in my country (Cyprus)i would love to thank you very much for the great ,great work!!! Reply @elenabond670 @elenabond670 1 year ago You are such caring and kind person to share all of this for us. I am following your basic steps. 9 Reply @soniabaker2504 @soniabaker2504 1 year ago Amazing video … thank you please keep exposing this most important and value information … so grateful to you both .. I salute Dr. Mark Hyman 10 Reply @Sammy.G @Sammy.G 6 months ago Amazing podcast! Thank you! ❤ 6 Reply @exposed.algeriansatanicnar1565 @exposed.algeriansatanicnar1565 1 month ago Excellent questions, perfect answers. Thank you gentlemen. Reply @blujack100 @blujack100 1 year ago This content is wonderful and is consistent with many others on utube that I follow. This should be on a Frontline episode for a wider audience. Thanks. 5 Reply @Disirablepossessions @Disirablepossessions 2 months ago I think, maybe, after watching this, my brain is inflamed more. I love the education you provide please keep up the good work. Thank you. Reply @gerrybourgeois5185 @gerrybourgeois5185 1 year ago Thank you Dr Hyman !!! I love your pod casts !!! Your the best 🙏 3 Reply @ravingcyclist624 @ravingcyclist624 6 months ago Totally agree ! No sugar and no starch ! 9 Reply 1 reply @Annie23855 @Annie23855 3 months ago Thank you so much. I am dealing with sudden diarrhea lately, Diverticulitis & Arthritis. Hammer toe and fusion surgery next week, don't look forward to it; but hopefully can walk pain free again & sleep better. 👍🙏 2 Reply 2 replies @BasutuEquestrian @BasutuEquestrian 16 hours ago Great podcast- thank you! Reply @chrismurrell1102 @chrismurrell1102 6 months ago I have been treating for meningioma’s in my brain. Not just any but they embedded in bone causing hyperostosis. This lead to sudden hearing loss and proptosis of my right eye. I’ve been through surgery and radiation and thankfully I’m doing well. Meningioma’s are another conditions that is growing where there is very little information about the cause. Yes some are hormone driven and recent studies show a large increase in risk for breast cancer. I’m trying to do everything to prevent any further growth. Would love to see if there is a way to shrink them naturally. I’ve been told there is no way. Reply @sectionalsofa @sectionalsofa 1 year ago According to Neurologists "Team" Sherzai, saturated fat is extremely bad for brain health as the brain is largely vascular. The only fat the brain requires is Omega 3s. Processed and high glycemic "starches" and sugars are also dangerous, however fruits and some whole intact grains are beneficial. I'm with team Sherzai. 11 Reply @heidiwiner5822 @heidiwiner5822 1 year ago Dr. Mark has changed my life! Thank you and keep the podcasts coming…my doctors at Brigham have no clue, unfortunately. No names mentioned… 19 Reply 2 replies @jackiekavanagh3954 @jackiekavanagh3954 6 months ago Thank you so much I'm going to try that with my 19th month old grand daughter who is autistic ❤ 2 Reply @raewise6345 @raewise6345 1 year ago Such excellent content. Thank you so much! 7 Reply @rhodemb @rhodemb 1 month ago I have the Ultraprevention book written by Mark Hyman , and Mark Liponis ,can’t say how much I love it .🙏🏻🙂 Reply @jenadamsuk @jenadamsuk 2 months ago Lovely podcast and great information, thank you for sharing Reply @gordonhalstead9846 @gordonhalstead9846 4 days ago Boost brain 🧠 healthy ❤❤❤best 👌 presentation podcast truly informative thanks for sharing your professional brilliant knowledge at Dhru Purohit lecture podcast 👍 ❤❤ Reply @mollconn5998 @mollconn5998 1 year ago One of my favorite Videos!!! It’s always good to go back and watch .. Thank you ❤❤ 7 Reply @DeniseBraunBundy @DeniseBraunBundy 1 year ago Would be awesome to have content markers so listeners can scroll to specific information 31 Reply 2 replies @ldeanonmolina4077 @ldeanonmolina4077 6 months ago Thank you to you and to Dr Heyman.. very informative. 1 Reply @user-hk9zg2jy1u @user-hk9zg2jy1u 7 months ago Always so interesting and informative. However getting your standard general practitioner to perform any of these tests is daunting. Also insurance or lack of always come in play. Why would they want you to treat with food and vitamins when there’s no money to be made. It’s infuriating. 4 Reply @dollyvandenbrink5211 @dollyvandenbrink5211 1 year ago Dr Mark. U r a Gift to Humanity. 4 Reply @Lovin_It @Lovin_It 6 months ago Dr. Hyman, thanks for explaining your journey with mercury. If you repeat the story in the future could you kindly speculate or explain how and where in China you think you obtained this mercury, and how many people might be affected in that country, etc. Thank you in advance. 2 Reply @benjaminotto5711 @benjaminotto5711 1 year ago It’s another time of the year. One need to set goals and take a bold step in achieving them. Remember success are not obtained overnight. It’s comes in installments; you get a little bit today a little bit tomorrow until the whole package is given out the day you procrastinate you lose that day of success. 7 Reply 25 replies @frankarcobello3149 @frankarcobello3149 1 year ago Love hearing you talk Doctor 6 Reply @jenniferschneider6979 @jenniferschneider6979 1 year ago Great interview and information , but nowhere did I hear the role that alcohol consumption plays in inflammation. Alcohol is a known neurotoxin and a pervasive problem in our society. Alcohol, even in moderation, is detrimental to our physical and mental wellbeing. Would you do cocaine or heroin in moderation? I don't think so! So few are willing, except for Dr. Daniel Amen, to touch on this subject. Just because alcohol is legal, doesn't make it safe to ingest. The younger generations need to know the truth. I have been a nurse for 40+ years and have seen what alcohol does to the body and to families. 215 Reply 35 replies @lindadupuis1531 @lindadupuis1531 6 months ago What I would give for a doctor like you in my area. The area of Canada I live in is so behind in the area of functional medicine. 2 Reply 1 reply @clairespace3371 @clairespace3371 7 months ago Life saving help in this interview. Many thanks. PS is it possible to make the environment in the room lighter so we can see you better? 2 Reply @booswalia @booswalia 1 year ago I made a big mistake in my younger years eating way too much sugar. I was basically a hummingbird. I stopped two years ago but my brain is still, well, broken. 6 Reply 2 replies @georgemarsilio5122 @georgemarsilio5122 5 months ago dr H. I've been doing everything you talk about for the past 7 years..I don't have a medical degree..but I gave a culinary degree..you should interview me ..seriously..I'll do it by on line link or one on one ...I'm 61 and have a hard job ..and eat healthy..never had a flu shot ever..and never got sick in the 7 years..I know what in doing 3 Reply @cindydavison5278 @cindydavison5278 1 year ago Thank you Dr H!!! Fantastic! ❤️ 6 Reply @javadhashtroudian5740 @javadhashtroudian5740 2 months ago I'm wearing a CGM as part of my biohacking... What should I make sure I'm below? Also how to reduce heavy metal. I'm 76 and was a functional alcoholic between 18 and about 30. I now drink about 3 drinks a week. Many thanks for video and anyone who can answer my questions. Reply @arpigracetarkhanian9684 @arpigracetarkhanian9684 1 year ago Divine WISDOM🙏 4 Reply @kimberlywarburton9371 @kimberlywarburton9371 7 months ago This video is so good!!!! Thank you!!!!❤❤❤❤❤ 1 Reply @eleanorsmith971 @eleanorsmith971 6 months ago How did you take care of the heavy metals. I have 2 metal fillings in my mouth and I do think this has had a very negative effect on my health. Is there a reasonable way to get this problem helped or resolved. 6 Reply @stefanweilhartner4415 @stefanweilhartner4415 6 months ago (edited) it is funny, my anti-aging stack pretty much reflects that focus on getting rid of inflammation. glycine + nac + msm + taurine + multivitamins + magnesium + b-vitamins + coq10 + fish-oil and low carb diet where i focus on a minimum of protein of 1g/kg and a huge amount of fiber from white cabbage, green wide beans, broccoli... if i deviate from that diet, i get hungry and my performance goes down. 2 Reply @loopraja1544 @loopraja1544 1 year ago Keep your gut healthy By fasting 22 Reply @asiyageorge1878 @asiyageorge1878 1 year ago I am so thankfull for all this information that am going to change ny diet a bit more Thanks to Dr Mark and Dhru Purohit GOD BLESS 3 Reply @loretomurraylm @loretomurraylm 5 months ago ❤ A MASTERPIECE ❤ Reply @elginb @elginb 1 year ago Dr. Mark is loquacious and loves to share his knowledge. Thus he makes an awesome interviewee but not so such a good interviewer. 2 Reply @jameskelly6479 @jameskelly6479 1 year ago Great ,some of the best I have heard. 4 Reply @Rainbow_1981 @Rainbow_1981 8 months ago Yes indian cooking 90% has turmeric..of course oil or ghee (I don’t use ghee)”)onion/tomato/cilantro/green chili/ginger or garlic veggies or lentils or protein (egg/chicken/meat/fish) n spices 5 Reply @primrozie @primrozie 1 year ago April 30th I had the "widow maker" heart attack. Sorry I don't remember the actual name of it. I also have type 2 diabetes. They told me I'll chew a baby asprin every day for the rest of my life. Should I not use this asprin? I've been working on my diet for a couple of years, sugar free, very low carb and healthy fats so this threw me for a loop! 5 Reply 1 reply @danutajaneczek1467 @danutajaneczek1467 3 months ago I live that idea, and it is so true.Send someone my way who thinks like you. Reply @danutajaneczek1467 @danutajaneczek1467 3 months ago I agree with you that that is great .❤ Reply @pmelaglover9913 @pmelaglover9913 1 month ago I really love watching this Dr. I am here for it all!! One question why does he seem to be burping constantly??? I probably noticed because I have a hiatal hernia and it causes me to have indigestion and burping after eating. Come on Doc what’s up??? Reply @annemariededekind6271 @annemariededekind6271 1 year ago Thank you.....very valuable 2 Reply @lucybraun8969 @lucybraun8969 4 months ago The problem with water filters is figuring out when they need to be replaced. I need an easy method for doing that, not some higher math formula. 2 Reply @ginacardarella @ginacardarella 3 months ago I noticed that when I have more very fat and eat way more sugar and carbs eyes smore. I don't know that would help sleep apnea patients but I think it would so enjoying this thank you. 1:28:11 Reply @golflouis52 @golflouis52 1 year ago Remember Hypocrates, "first do no harm"... first solution to inflammation is... Fasting, let your body rest for a while 13 Reply @MomentsDivine @MomentsDivine 1 year ago I remember playing with with mercury at the age of 5. I watched my older brother roll it around in the palms of his hands.. Of course I had to copy him. That and chewing on the lead paint crib railing. I still remember the teeth marks, lol. Not to mention the black mold I found in my house a couple of years ago. Lordy Lordy 🙏 5 Reply @carlettagoodrich-mann1377 @carlettagoodrich-mann1377 1 month ago Medical didactics. Set protocols for health And wellness. We look for actions that. Quality the measures for reduced inflammation from the colon to the gut. Thanks for this information 1 Reply @pmelaglover9913 @pmelaglover9913 1 month ago Would you give just the basic supplements one can t(are along with a good clean diet to help us get nutrients we need??? Reply @reddreilly422 @reddreilly422 5 months ago Does he say how he acquired such high mercury levels? Very curious 1 Reply @TheSandrad07 @TheSandrad07 2 days ago I have a dumb question 🙋‍♀️ if I have problems with yeast overgrowth is it safe for me to use nutritional yeast ?? Reply @graemegeorgeharrison2468 @graemegeorgeharrison2468 1 year ago So do I hear right that long distance running can create more inflammatory responses within the body? 3 Reply 1 reply @jokekelleey2071 @jokekelleey2071 1 year ago I like how we can speak in to both kind of people either you know the people that know all the big words and the little people like me that just know the small words like I like to quote the phrase piss off your autoimmune system then you start having problems 2 Reply @randallevins5143 @randallevins5143 6 months ago Dr. Hyman, I am in a state of disbelief you reference the rok-her-fella found-dalmation in a positive light. They are mass geno-geno-side (sic) at their "best." 4 Reply @kellio8087 @kellio8087 1 month ago Timeline 48:00. Even though feeding prisoners all healthy food and healing their brains changes them into a better person who would no longer commit a crime if back in society, the system won't care and will still keep them locked up. All that will result is a calmer prison. Reply @ByDesign333 @ByDesign333 6 months ago (edited) Chronic unmitigated stress of our modern life...u r not kidding! Not name, it blame it, tame it... Think it/link it......brilliant stuff! 2 Reply @peterpiper487 @peterpiper487 4 months ago Yes, it DOES mean you can't ever eat that again. Out of both sides of the mouth is NOT a way to teach people what the heck they need to be eating and avoiding. Reply @GregStew @GregStew 1 year ago Very insightful! 🤔 Reply 1 reply @Atheria444 @Atheria444 1 year ago I'm gonna disagree on the blanket statement that sugar is bad for the brain. The brain runs on glucose when not unnaturally forced to run on ketones. I know that Alzheimer's is now referred to as diabetes type 3 and that keeping your blood sugar down is very important, but that is different than eating quality carbohydrates/sugars. I find it hard to believe that a yam is dangerous. 19 Reply 16 replies @mishaanton5436 @mishaanton5436 6 months ago DR IS NO LONGWR AT CLEVAND CLINIC. SO DOES CC still have a functional medicine doc or section devoted to FM ? 1 Reply @sagelady2015 @sagelady2015 5 months ago Is the refrigerator filter okay to use? Reply @christinehobson4544 @christinehobson4544 1 year ago They shouldn't allow these foods, containing all sort of chemicals, to be sold, to the public. These Companies, are the ones, who are making us chronically ill. PLEASE!!! 9 Reply 3 replies @izzzzzz6 @izzzzzz6 7 months ago Eggs get a bad rap because of the way most of them are produced. Personally i have had zero egg in 20 years and probably 42 years since i ate an actual piece of egg. 1 Reply 2 replies @Franklin-pc3xd @Franklin-pc3xd 6 months ago Okay, false alarm, the guest isn't Jon Stewart - go ahead and watch this, looks pretty good! 1 Reply @taylorIndustrial @taylorIndustrial 5 months ago Wow, the part about lead really caught my attention. Reply @susanjannarone135 @susanjannarone135 4 months ago Why not send book profits to the American Academy of Environmental Medicine? If you figured all this out without looking over their shoulder you’re a genius. They are frequently attacked by big petroleum, big “medicine” and big Pharma. 1 Reply @achieverspoint.3610 @achieverspoint.3610 7 months ago What about pure mustard oil is that fine for health Reply @CptApplestrudl @CptApplestrudl 6 months ago With a little adjustment the doc would do a decent Morgan Freeman impression. Reply @Aliya-gh2ec @Aliya-gh2ec 2 months ago I wonder if those Palestinians put on weight during the.Intifada as the lady did who was worried about her daughter returning from Israel ? Those Palestinians must have been under terrible stress over a prolonged period since the original Intifada.in 1948. Have they been obesce or overweight ? Maybe one of the reasons that we have so many health problems and chronic disease is because we support war and deal in the weapons trade and repeatedly go to war. It's a consequence for our collective health, which maybe we are in denial about. Reply @sylvanacoleman8273 @sylvanacoleman8273 7 months ago What is dr hymans contact email need to know where to get recipe for his shake. Both wonderful people Reply @jenniferbrown3782 @jenniferbrown3782 1 year ago CGM’s are 3k for 2 weeks. Great in theory but not helpful unless you already have the cash that you could see an amazing functional med Dr anyway….. 3 Reply 1 reply @nosretep1960 @nosretep1960 6 months ago My friend was a prominent Hindu high priest,( retired to teach economics and finance and London school of economics) knows ayurveda sideways. Where did it come from? Hippocrates...🤔 I believe both of them, even if I don't know Hippocrates in person... 1 Reply @lynndomenech4229 @lynndomenech4229 1 year ago What is the name of the company you mentioned that sells electrolytes? 2 Reply 2 replies @Jennifer-gr7hn @Jennifer-gr7hn 1 month ago Wait, so you're saying root cause analysis?!?!? Critical thinking? Making science/medicine FUN again? Being sarcastic. As a nurse who was before a nurse, interested in way more including nursing, like psychology, philosophy, theology, art and science. We're human! We're more than one thing. Gestalt, right? :) We are greater than the sum of the parts. This is a real doctor...and it's a shame that this is rare vs common which is what it should be. Reply @eugeniaolatoye6580 @eugeniaolatoye6580 1 month ago This means that those of us in Nigeria are in trouble. Where all manners of treated water are sold but you never know how pure is the water. What do you advice? Reply @stephx9759 @stephx9759 7 months ago This is basically one big ad for supplements. 5 minutes in and we already have drops and a water purifier. Supplement industry is quite young but already really big on social media, and the funny thing is people don’t notice. Look at these beautiful, well spoken people, carefully his video on purpose. 2 Reply @carmenchaux67 @carmenchaux67 2 months ago Oils that he ref as good MCT oil but it isn’t good . Someone please explain how is the brain going to be feed with a toxic substance of triglycerides. Amyotrophic lateral sclerosis (Lou Gehrig's disease). Taking 2 grams to 4 grams of threonine daily for up to 12 months does not seem to slow the progression of ALS or reduce symptoms. There is also some evidence that threonine might actually worsen lung function in people with ALS . I try the MCT oil and pretty bad reacción made look for info. Can you explain it please ? Reply @kuk3559 @kuk3559 1 year ago Eat this info start at 40:00 23 Reply 3 replies @meeshiemeeshie @meeshiemeeshie 4 months ago (edited) What filter filters hormones antibiotics drugs etc? If the city can’t do it what can I buy to do it? 1 Reply @yolandagrabowski6043 @yolandagrabowski6043 6 months ago By experience I find, water helps me to remember. Reply @lauragiannakas2290 @lauragiannakas2290 7 months ago This doctor is so brillient but its depressing because rhere are answers but some people do not have the time or money for this its si sad 2 Reply @sheilahollinshed933 @sheilahollinshed933 2 months ago I have many cycts in both kidneys 1 Reply @pmelaglover9913 @pmelaglover9913 1 month ago How I wish I had known many years ago !…, Reply @debbieminton5885 @debbieminton5885 3 months ago Can people send you a blood sample and have you check for these things? Reply @nicenonya3 @nicenonya3 6 months ago Sugar 32:20 2 Reply @1treehill149 @1treehill149 7 months ago Fasting hydration sleep organic ..foods beef collagen edta chelation 1 Reply @ellenmootoo9377 @ellenmootoo9377 2 months ago What about brain fog I have been told I am suffering from graves disease I am feeling I’ll I am feeling backward my brain has become so slow.I don’t know what day of the week I have to look at the daily paper to know what day I have could you please tell me how to remedy my illness thank you dr. Reply @julianavillanueva7385 @julianavillanueva7385 6 months ago COVID cause huge inflammation problems. I have had -almost 4 months. Terrible pain. Reply 2 replies @jokekelleey2071 @jokekelleey2071 1 year ago 1.11:40 . , Minute it's the main part this is what I've been waiting to see waiting to hear somebody say that I think the Aztecs in South America tortured their prisoners by feeding them corn everyday and then I imagine that a couple psycho people went out and killed somebody and then they couldn't figure out who it did it so an innocent person got punished and then after that all her broke loose because people were killing each other because of bad or innocent mistakes 1 Reply @Disirablepossessions @Disirablepossessions 2 months ago Does alcohol cause brain inflammation? Reply 1 reply @bencyber8595 @bencyber8595 1 year ago in 2005 the NOBLE PRICE winner is awarded by a person who talk about INFLAMMATION ! 4 Reply @webersteve1547 @webersteve1547 5 months ago Interesting, but overly monetised 😢 Reply @suzannemastragostino9950 @suzannemastragostino9950 7 months ago If nuts and seeds are healthy, then why is their oils not great? 2 Reply 2 replies @katrynreel-myers3993 @katrynreel-myers3993 6 months ago How is a C-section harmful? I might not have anymore children if this is a risk. Thankfully I had one natural birth despite gestational diabetes and hypothyroidism. 1 Reply 1 reply @weniwidiwici726 @weniwidiwici726 6 months ago Hey Dr. Hyman, allow me to school you on something lthat is not taught in med school.... A soldier is in the Army, a Marine is in the Marine Corp, Seals are Navy, and a person in the Navy is a Sailor, ot a soldier... Reply @fergusfarm3793 @fergusfarm3793 7 months ago (edited) Yikes. Another reason to avoid the ER. A knackered Dr on the night shift fueled by caffeine and adrenaline 1 Reply @peterpetino9590 @peterpetino9590 1 month ago How can I regrow the hippocampus. Reply @patrickdziva4877 @patrickdziva4877 1 year ago Thank you so much but please try to make short videos 4 Reply 1 reply @hkurland7015 @hkurland7015 1 year ago Dr.Have you seen Asian Mind-Body Techniques Revealed, a book on stress reduction? Reply 1 reply @maviscoils9672 @maviscoils9672 1 year ago There is very few foods today that are not processed the supermarket is a nightmare l look round and think what can l eat that’s healthy..... not very much 😩😩😩 Reply 1 reply @zinnia20207 @zinnia20207 2 months ago If you reheat your oils don't they become a trans fat? Reply @bh9262 @bh9262 2 months ago I never eat that stuff but my iron is high Reply @Chris-tw8fu @Chris-tw8fu 5 months ago Not true that most people are dehydrated.over filling with fluids is as detrimental as overfilling with food. Reply @666Troll999 @666Troll999 1 year ago All the kids on psych med's is why I don't drink tap water. 1 Reply @patriciadupree3636 @patriciadupree3636 7 months ago Glad I was not his patient in the bad days . Reply @galahadthreepwood @galahadthreepwood 4 months ago What should we be eating? He didn't mention meat and fats from ruminant animals Reply @BiGChinGSvideos @BiGChinGSvideos 5 months ago Great video please hit me up I would love to add to this Reply @chandsultana @chandsultana 7 months ago It's interesting they did not body and brain are connected Reply @febiaivy4702 @febiaivy4702 1 year ago Now the petrol conflate, how can gavement letit increase R4 per litre? Reply @dalepidcoe8300 @dalepidcoe8300 5 months ago Dale Pidcoe DuBoistown, Pa. Will YouTube show me episode 3562 of the classic Sesame Street that originally aired on PBS at noon on Tuesday, January 7th.,1997 with Kingston Livingston III's voice announcing the sponsors of the letter N and the #4 in scene #6? I hope they have it on YouTube on all cable TV sets in Hughesville PA at 5:43PM tomorrow so it can be eligible for what did you think of this video?!!!! 0:03 🥰🇪🇬🤪🇮🇶😆🥰😏😔🥱😠☹️😆🥰😏😔😸🇧🇬🇧🇸🇨🇫😘🤭😡😮🦾💪🤜🖖🤢🇬🇦🇬🇱😯😵😷🤡👾👺💤😼💜💞👥🦴🙁😲🇬🇭🤥😈🌛☝️🤲💪😷🇺🇦👺💤 1 Reply @harrietdeklerk7255 @harrietdeklerk7255 1 year ago How do you get rid of heavy metals? 2 Reply 1 reply @martinezstre @martinezstre 2 months ago There are Different sugars... Reply @cornstar1253 @cornstar1253 7 months ago Where i live, drinking and storm water is filtered and discharged to the ocean. Reply @galaxywanderer5945 @galaxywanderer5945 6 months ago who in the world will sit to watch and listen for 2 hours?????????????????????? 2 Reply 2 replies @deannadeason1850 @deannadeason1850 1 month ago So we need to heal our earth,where we get our food source ,our water and then our bodies ? Right? This is why we are getting sick. Our Earth is sick our water sources are sick. I can see why every two to three generations we have a massive Die off.We seriously need to take care of our world. Reply @brionaturner6412 @brionaturner6412 1 month ago Spring water is the best Reply @ShivaniSuri-fs5tz @ShivaniSuri-fs5tz 6 months ago eating should be good tabhi possibl ha agar acchi slaah kahi se mil rahi he planet ayurveda ma bhot acha guide karte ha 1 Reply @brionaturner6412 @brionaturner6412 1 month ago That's why I used Bobby app Reply @halibux6683 @halibux6683 3 months ago $95 trillion bucks will be like a hundred bucks... 😂 Reply @paulhailey2537 @paulhailey2537 1 month ago RED MEAT SAVES LIVES Reply @LouScott1012 @LouScott1012 2 months ago Okay, so where is the mention of anti inflammatory foods? There should be some mention of foods such as berries, types of fish, flax, etc, so where is the mention of those types of anti inflammatory foods? 🤔 I am REALLY tired of hearing just the negatives and the preaching nature of these talks with ZERO mention of ANTI INFLAMMATORY FOODS. Very deceptive tag line, but of course a Cleveland Clinic doctor cares about money and not helping people. 1 Reply @normanpouch @normanpouch 6 months ago What a great guy. I am a farmer growing wheat. I will stop this year its killing people. Big sorry. 3 Reply @bencyber8595 @bencyber8595 1 year ago is this a TOP topic Reply @pranava9862 @pranava9862 6 months ago I'm waited to hear about the mercury poisoning, how he may have gotten, how did he know thus. Etc im at 20 min in. You skipped such important data, BTW, cit our talking in the dark, depressing... 1 Reply @kurakuson @kurakuson 7 months ago (edited) "My Story" It was a though time, had a lot going on, but the moment "it" hit *My Balls, thats when I got serious; " the straw that broke the camels back". Reply @kimberleychute5462 @kimberleychute5462 2 months ago Oxalates??? Reply @bimbonment @bimbonment 3 weeks ago Doc even sounds like Jon Stewart! lost twin? Reply @legalbeagle5712 @legalbeagle5712 1 year ago Mercury in body...how to get rid of? Reply 1 reply @vivafamilia7867 @vivafamilia7867 6 months ago Hmm, new research is showing it's your fiber intake. Reply @mmmali3700 @mmmali3700 2 months ago Oxalic acids in rainbow...... ? Reply @stilmotionpicture @stilmotionpicture 1 year ago Broccoli oil!?? 😂 4 Reply 1 reply @Covencraft @Covencraft 10 months ago Gdi these videos always tell you don't eat this, stuff we all know, they never get to exactly what to eat Reply 1 reply @vickieharris3850 @vickieharris3850 7 months ago I want clean eating..show me how Reply 1 reply @jfresh2054 @jfresh2054 5 months ago People act like inflammation is bad. Excess of anything is not good Reply @galespressos @galespressos 1 year ago Why do they name it vegetable oil. That is false advertising. 5 Reply 3 replies @ericag.6139 @ericag.6139 3 months ago 48:00 Reply @Bibagodiva55 @Bibagodiva55 6 months ago And, I'm NOT a Fan of ZARA...BUT: the spanish Leathermanufactur IS worldknown as excellent Craftmanship....stupid Girlie ! They wouldn't not sell such a Crap...maybe, it is not a real Bottega Veneta...because Italians makes also excellent Leather-Products! Reply @laurel1854 @laurel1854 1 year ago crazy thing to sit and listen 2 hours?! inflammation, that's what it doesn't reduce! SORRY! 3 Reply @annmilby4599 @annmilby4599 5 months ago Will C B D . Help our . Body if taken everyday Reply @yolandagrabowski6043 @yolandagrabowski6043 6 months ago I kill a spider saying, drink water, have a good day. Reply @rpratt7718 @rpratt7718 3 months ago (edited) I love Hyman but Why do you have to talk fast? Reply @JoyPhotography @JoyPhotography 3 weeks ago Love Dr. Hyman, but does he really think the Rockefellers are doing something good?? Reply @Dana-vq1tk @Dana-vq1tk 2 months ago Clearly you haven't met the Ravicher clan. Reply @luzlombardi6747 @luzlombardi6747 1 year ago Mercury poison from what ! Reply 2 replies @nonenow2020 @nonenow2020 2 weeks ago Get to.the.point Reply @345kobi @345kobi 4 months ago (edited) 132 Reply @richardwells8954 @richardwells8954 1 year ago WAY TOO LONG. 3 Reply @tibaross4461 @tibaross4461 6 months ago To long video. Reply @mbcmaui @mbcmaui 7 months ago No kidding Reply @johnvorkman1272 @johnvorkman1272 1 year ago TOO LONG!!!!!! With all the interesting videos I want to watch, I don’t have time to spend 2 hours on one video, and after awhile of listening to you guys, I don’t even hear what you are saying any more. Please learn to edit your videos. 10 Reply 4 replies @sallymae7009 @sallymae7009 36 minutes ago Waste of time! Absolutely zero information that’s helpful. HOW did he detoxify from mercury poisoning!?!?!????!!! HOW did he do the same for his patients! Ugh, every time I watch an interview with Mr. Hyman it’s a waste of time! Garbage interview. Reply @mymillionaireclub7591 @mymillionaireclub7591 5 months ago Rockafella is a joke... Reply @discerningacumen @discerningacumen 7 months ago Nothing good (or true) can come from an evolutionist who is a liar. 1 Reply @americandesitraveler8607 @americandesitraveler8607 1 year ago So Depressing talk sorry didn’t like . 1 Reply @clairespace3371 @clairespace3371 7 months ago To change your neuro chemistry by changing your thoughts see the REMMERT METHOD. Steve and ODILLE Remmert's programme, books etc. Addressing the point (1 hr 5 mins in) that your conversations stressful V loving changes your brain chemistry. Reply @myrnaleon8464 @myrnaleon8464 2 months ago You never mentioned what caused your toxicity Dr. Heyma.n 1 Reply