Do we finally have control over ageing? | Prof David Sinclair

Do we finally have control over ageing? | Prof David Sinclair 129,912 viewsSep 16, 2021 NUS Medicine 8.85K subscribers Ageing is inevitable, but what if everything we've come to believe about ageing is wrong and we're able to choose our lifespans? What if ageing is a 𝑡𝑟𝑒𝑎𝑡𝑎𝑏𝑙𝑒 disease? In this week's #HealthyLongevity #webinar, Prof David Sinclair from Harvard Medical School shares a bold new theory for why we age. Prof Sinclair is also the author of "Lifespan, Why We Age – and Why We Don’t Have To" (https://lifespanbook.com/ ). Register for upcoming webinar​​ sessions at https://nus-sg.zoom.us/webinar/regist... #NUSMedicine​​​​​ #webinarseries​​​​​ --- References: - Closing video source: https://www.youtube.com/watch?v=vIFEp... Disclaimer: The opinions and advice expressed in this webinar are those of the speakers and do not represent the views and opinions of the organizers and National University of Singapore or any of its subsidiaries or affiliates. The information provided in this webinar is for general information purposes only as part of a general discussion on public health. The information is not intended to be a substitute for professional medical advice, diagnoses or treatment; and cannot be relied on in place of consultation with your licensed healthcare provider. All Rights Reserved. All of the proceedings of this webinar, including the presentation of scientific papers, are intended for limited publication only, and all property rights in the material presented, including common-law copyright, are expressly reserved to the speaker or NUS. No statement or presentation made is to be regarded as dedicated to the public domain. Any sound reproduction, transcript or other use of the material presented at this course without the permission of the speaker or NUS is prohibited to the full extent of common-law copyright in such material. 428 Comments rongmaw lin Add a comment... Lucrezia Dippolito Lucrezia Dippolito 6 months ago My mom is 98 and she has glaucoma. Her mental state is good except for a little memory loss. I wish she could be part of your trials for sight improvement. This would be a miracle for her🙏 52 Natty Dred Natty Dred 7 months ago (edited) Longevity Rockstars. Straight up science, no click bait. No toxic doom peddling, or impossible promises. An upbeat message with suggestions for action at the end of each show. It's hard to believe this channel exists. Thank you! 31 Earla Weese Earla Weese 6 months ago (edited) Thank you so much, Dr. David Sinclair for all of your work and research. You and your team are truly a blessing for the human race. Thank you to all of the scientists and researchers currently working on life extension and longevity. 10 Nguyễn Thị Bích Ngà Nguyễn Thị Bích Ngà 7 months ago (edited) Extremely thanks to Professor Brian and Professor David for sharing. You are the legends. Can't wait for the next show to learn more about reprograming. 34 Aaliyah Lee Aaliyah Lee 6 days ago I have been watching Dr. Sinclair. His book is also very educative. I love that book. In there, there's no point increasing lifespan without health span. The goal should be to live longer while staying young and healthy. Sinclair believes that in the foreseeable future, it's possible for humans to live beyond 120 or even 150, without the frailty, diseases and disability we now associate with old age. I hate aging and the illnesses it brings over time. This is why I am now taking NMN supplement by Vitruvin constantly. The Sheekey Science Show The Sheekey Science Show 7 months ago Really great conversation addressing some important questions in the field! 83 250txc 250txc 6 months ago Both these guys come across very well and with NO hidden agendas ... Good luck on your research. I'm 63 and feel great after cutting sugars\CARBS as low as possible AND eating only twice aday usually; going another ~20 yrs might be possible so I'm hoping for a breakthrough from you guys. 19 Rapamycin News Rapamycin News 4 months ago Great to see the progress at NUS, and also in David's lab. The reprogramming efforts are really interesting - but my concern is that it may be decades before it gets translated to the clinic, and will be expensive if it turns into a therapy. Perhaps Altos Labs can speed things up. I think the NUS efforts at identifying supplements and drugs that are most helpful in aging are the big win for the next 5 years - drugs like rapamycin. V. Hoppen V. Hoppen 3 months ago Thank you @Dr.Sinclair for all your work. I used to get so frustrated when medical professionals would tell my father, you're getting older so we aren't going to treat Xyz... made no sense to me. you are proving we all deserve treatment regardless of age Brent Nally Brent Nally 7 months ago Two longevity legends in one epic video! Bravo! 67 The Macso The Macso 5 months ago Can we please fund this man with everything he needs? 4 Hacking The Human Time Machine Hacking The Human Time Machine 6 months ago Wonderful presentation, thanks! Can we expect one day to be able to read a paper on your results in primates?? 5 Irish Willow Irish Willow 6 months ago Not sure if David's theory will reverse or slow down aging but the supplement he recommends sure give energy to my aging years. Much better than not having the energy to get out and enjoy. 16 Gonzalo De La Maza Mendizabal Gonzalo De La Maza Mendizabal 6 months ago This is such an interesting topi! I am curious, I understand that theoretically we can use many different interventions to tackle all the hallmarks of aging, from telomerace to increase telemeters, Partial reprogramming to improve mitochondrial health and restore epigenetic youthful patters as well as the use of different proteins to remove wastes. But genetic instability seems impossible to treat. Correct me if I am wrong. I hope that accumulated mutations don't have much of a damage them self, rather its just when they occur that they affect other parts of the ageing process. 2 Dan Dan 7 months ago happy to see more of David and reverse-aging research 31 Archanjel Michael Archanjel Michael 5 months ago I read his books about intermittent fasting..and resveratrol...I learn lot from him, and im very grateful ..... his studies are very interesting... .. . My grandfather reach age 96 and he practised intermittent fasting...i do believe that healthy lifestyle can impact immune system and general health ...organic superfoods, exercise and positive mindset are great way how to live longer and more healthy.... 3 Diana Dalo Diana Dalo 7 months ago HRT and DHEA etc for menopausal women is a huge longevity question and it would be great if it was addressed....seems quite important since it regards 50% of the population 18 samantha porter samantha porter 3 months ago This man is a genius! Nils from Alaska Nils from Alaska 7 months ago Excellent video - thanks for posting 4 ki5ngau ki5ngau 4 months ago Two of the smartest persons giving free advices on anti-aging, nice. Long Vu Hoang Long Vu Hoang 6 months ago Thanks Prof. David very much. 3 Irene Hwang Irene Hwang 5 months ago A fascinating idea, 80 or 90 years is the most extended life for people. We hope just facing death in proper condition, healthy body, happy life, not a life for a much longer time. Intermittent fasting and taking astaxanthin is the way I'm doing it. DrArvind Poswal DrArvind Poswal 6 months ago Very informative 👍 1 Yayang Tapir Yayang Tapir 4 months ago (edited) A big bonus from science to human kind - Dr Sinclair. I'm curious what he is drinking right now , it's not wine for sure!☺️ mateen haq mateen haq 6 months ago Hi, Sir David is there any breakthrough in the treatment of M.D involving neuro cells? 1 Lucrezia Dippolito Lucrezia Dippolito 6 months ago I have been taking NR for 2 years now and I look and have the energy of a 30 year old. I’m 64. I exercise, fast and vegetables 90% of my diet. I’m waiting to purchase Dr Sinclair’s biological age testing kit. Where can I get one in Canada? 1 Brylan Jacobs Brylan Jacobs 1 month ago I have to measure the anti-aging effect of a protein in human cell lines. I want to use epigenetics as a marker for aging, alongside senescent markers. Will the differences in methylation frequency of cells in particular parts of the cell cycle and senescence correlate to the reversal of the aging process after treatment. mark veen mark veen 6 months ago (edited) Seen people age 50-60, looking and acting like 30 years old. With perfect skin and wrinkle free. Doing 0 supplements, fasting, superfoods or any other so called health practises. They are just in tune with their body and live joyfully. Having good genetics helps alot also. Your own intuition can be your best tool. What to eat and when to eat. Most people are not in tune with their body's circadian rhythms, however. Also seen people age 40 doing all kinds of supplements, fasting and exercise for decades. But they seem to have aged terribly. So untill we see 60 year olds looking and acting like 20. Nothing incredible special is going on. It's 2021 and I think we're just started to grasp the basic understanding how aging works. it's incredibly complex. In this timeline your best bet is probably living as naturally and in tune with nature as you can. Looking at the blue zones. The real paradigm shifts are probably still a few centuries away. 16 norhaina lidjamansali norhaina lidjamansali 6 months ago hi thank you for a great show what is the effect of vit d and vitamin c in aging. Lina AbouDheir Lina AbouDheir 6 months ago Loved it Soooo much learning Thaaaaank you 1 Shelley Swyer Shelley Swyer 6 months ago (edited) This is awesome. I want to know how at 51 David doesn’t have a single grey hair with a biological age of 34.1 I think he said. 5 Patricia Búdová Patricia Búdová 6 months ago Prof Sinclair is really getting younger 😮 He looked different/older in Tom Bilyeu show two years ago 🤔Or is it some kind of screen-filter?…If not, the difference is amazing 7 Ali Alabdulal Ali Alabdulal 6 months ago I wish Dr David discuss several concerns on NMN and Resver been raised and discussed by other specialist in the field and published on Youtube so one can feel ok taking these supplements with confidence 7 bigblockjalopy bigblockjalopy 5 months ago Lots of people with a medical background critizising Sinclair, however they look their age or older. Sinclair looks 20+ years younger than he is. Guess who (as a layman) I am trusting. Besides, what he says sounds plausible. 14 J Andersen J Andersen 6 months ago Great video! aymeric B aymeric B 5 months ago Would be nice to have the time steps :) FireFacts FireFacts 4 months ago (edited) With the current rate of life span expectancy increase in 60 years from now the average lifespan will be between 93 and 99 years. Meaning that about half the 30 year old's of today will live to be over 100 years old. And that is not taking in to account things like the benefits of intermittent fasting, Gene therapy, NmN, bio-printing and so on. Liran Gaston Liran Gaston 7 months ago TOP LEVEL OF HUMANITY 7 Roger Isaksson Roger Isaksson 4 months ago I’d like to live until: 1. The inevitable fatal accident happens 2. Until I’m bored of being a human being with limitations 1 Anamul Islam Anamul Islam 6 months ago Some say resveratrol is not good and actually interrupts the cellular process. could you advise? 4 Cal L Cal L 6 months ago I'd like seeing a scientific study on the difference in people born on different seasons, like summer,winter, spring and fall and how it affects them in adulthood. 1 Addie Frahm Addie Frahm 4 months ago I would like to order NMN..Resveratrol..I’m having a very difficult time finding a product that is what it says it should be. Can someone please please recommend some brands for both these items. There’s so much on Amazon there’s so much everywhere a person feels overwhelmed and I just don’t wanna order something that would create a problem instead of solving a problem Kenneth Marquis Kenneth Marquis 6 months ago Sleep, less stress, exercise, proper diet and nmn resveratrol is keeping Sinclair young. Try it 4 Gg Fla Gg Fla 6 months ago Can you talk about NMN causing more inflammation thus being harmful rather than beneficial. 2 Bobby Miller Bobby Miller 6 months ago It’s great to slow down the aging process. They should look into how to eradicate HPV virus in humans and all other Virus. 1 MarcoGee MarcoGee 6 months ago Could quantum computing accelerate the progress of ageing ? 3 Vestu Vestu 2 months ago Sinclair does look ridiculously young for someone who's 52 :D 1 Chrono Chrono 6 months ago Time is not toxic, bad habits are. 5 N1mBUS Music N1mBUS Music 5 months ago ashwaganda is a spectacular herb that lowers blood sugar as well. it seems sugar is the enemy 2 Lair Heron Lair Heron 5 months ago We'll have to solve our short life spans if we ever want to explore the cosmos. RILEY (SlotDog) PLAYS SLOTS (He's a dog) RILEY (SlotDog) PLAYS SLOTS (He's a dog) 3 months ago (edited) These guys are talking about wanting to live longer . It seems like I'm living forever . I've been alive for as long as I can remember. My goal to keep living forever. So far my goal is 100% successful. Have not died even once. So far so good . I've been around for 65 years and haven't done anything. But I've achieved my goal . Time to eat cake and light some candles John Marrs John Marrs 5 months ago Should combine Sinclair’s techniques with the Israeli hyperbaric oxygen therapy that lengthens telomeres. That might be the holy grail. 1 Bloke About Town Bloke About Town 7 months ago That 92 year old man at the end of the video, wow! Bring him on the show for an interview. 7 Steven Lucks Steven Lucks 6 months ago I take NMN and Trans-resveratrol and 100 grams of pre-biotics - I took the UCLA test and my biologic test age is 63 and by candle I am 70. I took the microbiome test and I have no low grade inflammation. 4 Aztec Warrior Aztec Warrior 4 months ago (edited) Does anyone noticed that David looks younger than he did 2 years ago. I’m not even joking . Angelica Camargo Angelica Camargo 6 months ago Do you guys know where to find information in regards to “eating less”. It is mentioned by many doctors but I don’t think I have heard what exactly does that mean in regards to calories. In the video is around min 9:30 Donna Houston Donna Houston 6 months ago Does anyone know the molecules that’s being used to reverse Blindness in mice? Jo Wong Jo Wong 3 months ago fantastic Aging Backwards Photo Evidence of Aging Reversal Aging Backwards Photo Evidence of Aging Reversal 5 months ago Practice and theory is very different Billy Hanafy Billy Hanafy 6 months ago Anyone knows what drink that Dr. Sinclair was drinking? It looks like a breakfast replacement. Thanks. 3 Reflect Reflect 6 months ago These two professors have got a 2 years age difference, yet when you look at them this gap is evidently larger. I bet Prof Sinclair is already applying his knowledge on himself (with a little bit of botox I would say hahah)! He looks great! :-) 1 UHFStation1 UHFStation1 2 months ago I hope spinal bones can remodel more correctly. No more spurs or stenosis crushing our nerves. フᎶフشپんフキん𐡀んフ冰𐡀ん徐冰𐡀んキフんپشフᎶフ フᎶフشپんフキん𐡀んフ冰𐡀ん徐冰𐡀んキフんپشフᎶフ 4 months ago Do we finally have control over ageing? No, we don't. 1 Midas Snap Midas Snap 6 months ago David continues to get slightly older looking each year. When he starts looking younger I'll know they have figured out something. 8