Dr. David Sinclair on Unlocking the Secrets of Aging | The Keep Going Podcast

TB12 Sports 22.6K subscribers Our guest for today's episode is Dr. David Sinclair. David is a long time friend of TB12 and a tenured Professor of Genetics at Harvard Medical School. His book, Lifespan, which we sell at our Performance & Recovery Centers, became a NY Times Bestseller in 2019. While David is best known for his work on genes that delay and reverse aging, he has also published over 200 scientific papers and has co-founded a variety of biotechnology companies in the areas of metabolic diseases, inflammation, infectious disease detection, and more. What we appreciate most in our conversations with David is his unique ability to simplify these complex concepts in a way that's easy for everyone to understand. In our discussion today, we focus on the types of food David believes we should all be eating, how to time your food intake to minimize the stress it puts on your body, and the importance of sleep and the circadian rhythm – something we focus on with all of our clients at TB12. Listen on Apple Podcasts: https://apple.co/3nAZVBM Listen on Spotify: https://open.spotify.com/episode/5k8C... Shop » https://tb12sports.com/shop Twitter » https://twitter.com/tb12sports Instagram » https://www.instagram.com/tb12sports/ Download the TB12 Mobile App » https://tb12branch.app.link/TB12Mobil... 185 Comments rongmaw lin Add a comment... Modern Healthspan Modern Healthspan 1 year ago Brilliant Interview! Thank you for bringing Dr. Sinclair in. My wife & I follows Dr. Sinclair work's for a while, he inspires us that " "Why we age and why we don't have to! We are taking similar approach to his protocols and now feeling more enthusiastic and both of us successfully reversed our biological age. We are very grateful to have chance to study his work and his book. 45 YoungerByTomorrow YoungerByTomorrow 5 months ago Very interesting and exciting interview. As a 59 year old personal trainer and Epigenetic Coach, I appreciate you getting this type of info out to the public. So that can learn how they can take their health and aging into their own hands. Live , long and prosper ! 1 Kimberly LaCroix Kimberly LaCroix 1 year ago Excellent interview! I have been following Dr. Sinclair's work for a couple of years now because as a 46 year old female always on the search for optimal health so thank you. As far as the interviewer, I haven't listened to you before, but excellent questions and I really enjoyed it. 9 TB12 Sports Beta Beta 1 year ago I fast 15 hours every day with no problem. I exercise using yoga, walking up steep hills, and riding my bicycle. I had a hard time getting to sleep. I tried a melatonin supplement and it worked well. I have been on a plant-based diet for 10 years and it has been an incredibly positive change. 29 D McMac D McMac 1 year ago This is a treasure for those who accept the responsibility of learning the "care and keeping" of the human body. 36 TB12 Sports Sema Aral Sema Aral 1 year ago Thanks to Dr.David A.Sinclair and interviewer John.🙏Just ask the questions we worried a lot in an goos order.👏This second listening made me understand more, probably will listen one or twice more.These diet makes me confused.In Lifespan i understood like, meat is bad ,,that 7 Amino Acids are bad to humans but on the other hand today Dear Biologist told us eat ,if you made an serious exercise at gym, which is a new hope to me.I 'm meat lover as well , i can never feel full with veges and that terrible carbs loads with sugar.I"m over 55 first time in my life taste sweet potatoes or rice or pasta .I never eat carbs but I have plaques in my neck around %20.So time to eat red meat once a week or never may be.What about Turkey meat, organic chicken are they life treating , I don't know.But Thank you thank you. YES he sounds like us and that part put us more shock , he is a normal human like us.Love his memories with his family and send my good wishes to his father.Sorry for his mum🙏.But her soul must be in piece for what his son is doing for humans.God Bless Mr.David A.Sinclair and his family.This world needs this calm talking Biologist a lot.Pls Pls more Podcasts like this in this question form is needed again.Pls don"t let us waiting long period of time.💝💝💝 7 Kris Jay Kris Jay 1 year ago i've heard a lot of David Sinclair interviews, this interviewer is one of the better in asking pertinent useful questions listeners care about and avoiding saying stupid things or focusing on irrelevant matter. 6 susy dyson susy dyson 1 year ago (edited) excellent talk great sensitive advice ! being too strict also can cause serious problem Ledo Mc Ledo Mc 1 year ago My question would be, what can a young person do to prevent aging? What would David do if he was all of a sudden 20 again and was able to start new? I heard that nmn etc for nad levels aren’t that good because young people alredy have youthful levels 5 Hoa Vuong Hoa Vuong 8 months ago We can strive to stay healthy and there are limits. When I was a teen, I look like my mom, slowly I turn out to look like my dad. 1 හරි මග උදෙසා හරි මග උදෙසා 11 months ago Dr David Sinclair that the best gift one can give is the knowledge. So we derive the gift which is invaluable. Many thanks. Dr.Jayantha Pathirana from Sri Lanka. 5 Linda Babayan Linda Babayan 2 months ago Fantastic I love listening to you Dr. David 👏🏼👏🏼👏🏼👏🏼👏🏼👏🏼👏🏼👏🏼👏🏼👏🏼👏🏼👏🏼👏🏼👏🏼👏🏼 S I S I 1 year ago (edited) Its really great on his diet tips and what he eats. Nice to know his view on the two schools on thought on whether to eat meat or not. Or whether to eat a lot of protein or minimal protein. He says he's in the middle. Wow. Exercise like bike riding a few times a week can reduce a fatale disease by 40% later in life. 6 청ずらたん 청ずらたん 3 months ago (edited) Very interesting. Like I always say: I'm not so hopeful about anti-aging research (I'm almost 90 years of age - but possibly kids around 30 today will see anti-aging research when they are my age). BUT: why always mice? We want to see the human cure. Why always talk about mice? What good does it do if he can play with mice's epigenome? It's good for the mouse race I guess! 1 chribjslaha chribjslaha 1 year ago David Sinclair, The most humble. 25 Kathy Dennis Guerrero Kathy Dennis Guerrero 1 month ago I fast for 23 hours daily with no problem. I do the OMAD diet as what Dr. David Sinclair is doing and I've been losing pounds since. I never felt this light and great at the same time. If ever I would feel hungry on those 23 hours of fasting daily, I would just grab some almonds or a raw banana, just what Dr. Sinclair has advised, and that's what kept me on this kind of diet. I don't feel too hungry or food deprived at all. Plus I drink lots of water throughout the day and a cup of green tea in the morning. I only eat a full regular meal at lunch time, that's what works for me. 666theninja 666theninja 1 year ago Bruce Lee slowed down his Ageing due to non stop Training, he was 32 when he Died but had a Body of a 18 year old. If Bruce had of lived it would of been interesting how his health and body condition was like now. 11 Corn Pop Corn Pop 10 months ago i was interested in anti-aging because of the stories of the Greek and Sumerian gods and goddesses and how they have eternal life because of something they had access to that mortal man did not. it was then i knew there was a way to to reverse aging. imagine parents, grandparents, and children all living in their prime for long periods of time. generation after generation how cool would it be to know your great grandparents as you know your friends or grandchildren as friends. 8 Lynda Bristow Lynda Bristow 1 year ago Thank you to all the little mice who are contributing to these and other scientific experiments. You don't have a choice and it's not a great life. I just hope you aren't suffering too much. 18 Crystal Greco Crystal Greco 11 months ago The most handsome & humble doctor!! 8 Zbigniew Brzezinski Zbigniew Brzezinski 1 year ago De. David looks much younger than 50 ! Congratulations ! 🎊🎉🎈🍾 10 Sleep Smart Smash Stress Sleep Smart Smash Stress 10 months ago (edited) The central theme to retard the rate of aging or escape accelerated aging which we are all at a high risk from due to pollution, poor diet, the lazy environment, stress etc is that if you have sad genetics you work for happy genetics. Zbigniew Brzezinski Zbigniew Brzezinski 1 year ago Could otosclerosis be treated some day using gene therapy ? DANTHETUBEMAN DANTHETUBEMAN 1 year ago (edited) In a perfect case how long do you think a person could live today David? 2 Zbigniew Brzezinski Zbigniew Brzezinski 1 year ago I didn’t know that some antibiotics could turn on some genes ! Really interesting ! 1 Areg Stepanyan Areg Stepanyan 1 year ago (edited) Don't forget to raise the mineral intake with using more liquids. It washes a lot out. KCl, NaCl, Magnesium, zink, iron/Fe etc. 9 Makayla Hollywood Makayla Hollywood 1 year ago I use 3/4 cp of milk to 1 cp in my coffee. I love it! And, i still feel very light, fasted. 2 Jose Matamoros Jose Matamoros 1 year ago (edited) Health should be first priority. TB12 is a start. 18 blaster91 blaster91 1 year ago Can someone ask David if he has any research on chaga. And the effect towards reduction of blood sugar? If it would be a good alternatives for people with high blood sugar in the morning 2 Wayne Wayne 1 year ago I’ve noticed that if I eat fibre before something sweet, I don’t get sleepy afterwards and suspect my blood sugar doesn’t spike afterwards. 5 Sleep Smart Smash Stress Sleep Smart Smash Stress 9 months ago If I were commissioned to do this chore of - Unlocking the Secrets of Aging - I will try the master key police and burglars use, or call a locksmith to tackle the lock and get to those secret stash. Calling a locksmith seems far wiser than a Harvard genetics professor. What does Dr. Sinclair know about tapping locks. Was his previous profession a nighttime bandit? trojanthedog trojanthedog 8 months ago (edited) I skip dinner. Never have liked food when it's dark. So 95% of my calories are taken between 7 and noon. Around 3 in the afternoon I like a cup of tea and biscuit. 3 Peggy Ferrera Peggy Ferrera 7 months ago Studying resveratrol and heart failure, what about this? I saw this on youtube, now I wonder if I should take this. Cheryl Negus Cheryl Negus 1 year ago Love Dr Sinclair. I purchased a lot of the anti-aging supplements online, but.... are they authentic? How can you tell? 2 Creepy Girl Creepy Girl 1 year ago I would recommend Intermittent fasting for everyone, the 8/16 diet. Eat lunch and dinner, skip breakfast. Once you done it strictly for about a week at most then the body is used to it and you will never really want breakfast. At least that's how it is for me and I used to love breakfasts, but now I feel better without it. 4 kter malkut kter malkut 1 year ago (edited) I think apart from diet Tom Brady takes other supplements? Is that treatment available to others? second question - can age reversal change a bio clock for pregnancy? ID ID 1 year ago The reason for BG spikes is intromyocellular lipid from animal fat and oils that prevent glucose penetration into cells, therefore, circulating in the blood in high concentration. 5 You can DO IT You can DO IT 1 year ago I know the main reason of the scratches on the CD. Is the oxidative state of body exposed to daily mold from air and mycotoxins and toxic substances, also a highly carb diet promotes mycotoxins and adrenal overdrive in the body. 2 chribjslaha chribjslaha 1 year ago Regarding Sushi, the sushi rice is mixed with vinegar and white sugar. That's the reason for the glucecose spike. 16 Simon Suh Simon Suh 1 year ago awesome! 3 Nothing Free Nothing Free 6 months ago David is in a process of a EXPERIMENT ! It is STILL unknown if the results will be positive or negative ! Give it 20 to 30 years down the road to actually see some of the results. There are many that follow and that will also contribute to results ! Keep in mind EVERYTHING got PRICE ! Good Luck ! 1 Malik Mehdi Malik Mehdi 1 year ago Can anyone please summerize the points or point out specially the part where he speaks about diet, exercise , fasting and sleep. Can’t wait and watch the whole video for that only. 1 Mark Whittaker Mark Whittaker 1 year ago Before I take the time to watch this can anybody tell me if there's anything new here or is it the same interview that Dr Sinclair has given a thousand times? 4 Darek Birton Darek Birton 7 months ago This man doesn't eat right, he takes high blood pressure meds every single day. He dyes his hair every day and dyes his beard every single day just like my aunt who does not want to show her grays by looks very young looking for her age of 74 years. She has no wrinkles. I have discovered the secret. I do a 6 Day Water only fast every month. I prep for 3 Days before and follow the 6 day water-only fast with 9 days of refeeding. I live a lifestyle without processed foods. I eat mostly plant-based foods and I do not eat pork or beef and little or no meat daily. 1 💰Happy888💰 💰Happy888💰 5 months ago Is collagen peptides just for skin? sjafei hasan sjafei hasan 1 year ago Here's where it gets confusing - if fasting leads to stress and signals a threat and hence create a defense mechanism i.e sitruin, resveratrol etc., is well noted. But, if we fast on a regular basis and becomes a habit, doesn't our body gets accustom to it, so that it no longer feels threatened? If so, then over time the fastings will lose its purpose. Can you explain if this is so? 8 ΓΕΩΡΓΙΟΣ ΔΡΕΤΑΚΗΣ ΓΕΩΡΓΙΟΣ ΔΡΕΤΑΚΗΣ 4 months ago Of coarse it is a good interview,if two good persons,but, how good thing is to have innumerable long interviews whith exactly the same content,and the listener spends-looses hours and hours only with rhe hope to learn one minute of substantial information ? It is like a sadistic torture R. S.E. R. S.E. 1 year ago great 1