mTOR Basics for Health and Longevity

#mTOR mTOR Basics for Health and Longevity Part 1 69 viewsSep 7, 2020 7 DISLIKE SHARE DOWNLOAD CLIP SAVE Wild Warrior Nutrition 3.17K subscribers In this video Dr. Mark Testa discusses mTOR, what it is, and why it is important to health and longevity. Topics discussed in part 1 of our mTOR series include: Part One - Too much mTOR activity good for growth, but bad for lifespan - mTOR as a nutrient sensor of the cell similar to Insulin - Easter island - isolated by soil bacteria - mTOR's ability to sense glucose, insulin, and protein, leucine and arginine (animal protein) and potentially creatine - mTOR as a regulator of protein synthesis and cellular growth (including tumors) -mTOR found in organelles (lysosomes) inside of the cell - How to inhibit mTOR - Inhibitied mTOR by AMPk which is stimulated by low nutrient (glucose) intake -- Dangers of suppressing mTOR too much. Learn more about longevity at: www.trainforlongevity.com Get our powerful superfoods at: www.pinepollensuperfoods.com Enter code: "WARRIOR" for 20% off your first order. #mTOR In part 2, Dr. Mark Testa continues to answer the question, "what is mTOR?" by expanding on some key concepts related to mTOR and it's role in maintaining optimal health, and longevity. Topics in part 2 of our mTOR series include: - Is less more? - Inhibition of mTOR may not delay aging itself, but may delay age-related diseases - How mTOR activation suppresses autophagy - inhibition of mTOR activates autophagy; i.e., using fasting and low protein diets for periodic rejuvenation - Inhibiting mTOR to preserve adult stem cell function in various tissues - Though mTORC1 inhibition clearly enhances overall lifespan, it may exert positive and negative functions on stem and immune cells that may deferentially impact aging - Senescence-cells that age or undergo cell division but not die, also negatively influence surrounding cells. - Rapalogs or mTOR inhibition may lower some inflammatory cells. This results in mTORC1 inhibitors inhibiting the SASP through various mutually nonexclusive mechanisms. - Rapamycin treatment prevents metabolic stress and delays cellular senescence. Learn more about training for optimal health and longevity at: www.trainforlongevity.com Try our products at: www.pinepollensuperfoods.com Get 20% off your first order with coupon code "WARRIOR" at checkout.