Lifespan (David Sinclair) and Rimon podcast

Book Review- Lifespan by Dr. David Sinclair Posted on October 18, 2021 by skeptvet As part of my efforts to learn as much as I can about both aging biology and also the effective communication of geroscience research, I have been reading popular books on the subject by influential figures in the field. While the details of the science are more accurately and thoroughly expounded in the scientific literature, the philosophy, history, and ethos of the aging biology field is often best explicated in books for the general public. And while I have been communicating to many different audiences about science for many years, this experience has centered on veterinary medicine, evidence-based medicine, and alternative medicine. Being relatively new to the aging biology field, I am enjoying learning the metaphors and techniques various authors use to communicate about the field to those who are not specialists in the subject. As always, I endeavor to share what I learn through this blog, so I will be posting a series of reviews of the aging biology books I have read. I am starting today with Dr. David Sinclair’s book Lifespan: Why we age-and why we don’t have to. Dr. David Sinclair is a bit of a controversial figure in the geroscience community. He is recognized as a talented and productive scientist. He is also an eloquent and persuasive advocate for aging biology research. Yet he is prone to hyperbole and enthusiasm that goes beyond what can be supported by reliable data. He is known for using, and at least tacitly or indirectly recommending, anti-aging interventions that have not yet been appropriately tested for safety and efficacy in humans. The ambivalence Dr. Sinclair inspires has been well-characterized by his friend, and fellow renowned aging biology researcher and author, Dr. Steven Austad: “He’s a superb scientist, as well as a superb salesman. You talk to him about science and you won’t find many more knowledgeable, incisive experimentalists as David. And then you can listen to the stuff he says on TV and be like, What the hell is he talking about??” Dr. Sinclair’s book is an excellent example of both the good and the bad in the popularization of science. He makes extensive and effective use of personal stories and anecdotes, and he humanizes even the minor characters in his story, offering engaging personal tidbits or colorful characterizations of scientists whose work he references. The writing is clear and entertaining, and the analogies and similes he chooses to explain scientific concepts are usually quite effective. He summarizes complex biology succinctly and accurately. Nuance and uncertainty are sometimes smoothed over, but not usually to the point of misleading the reader. Lifespan also does a thorough and respectable job of covering not just the science of longevity but some of the history of the field as even some of the philosophical and ethical implications of efforts to extend human lifespan. Much of the book goes beyond the science and research evidence, but that is often an important part of popular science literature—to put the evidence in context and explore the ideas and implications beyond the data. From the perspective of science communication, this is an enjoyable and effective book. Unfortunately, Dr. Sinclair’s book also contains examples of many of the flaws and foibles of popular science. He makes free with exuberant speculation, promises to the reader, extrapolation and exaggeration. He emphasizes his own credentials in a way that invokes an argument from authority, at least indirectly implying his speculations and beliefs should hold more credibility than can be justified by actual evidence simply because of who he is. Similarly, while he is careful to employ qualifiers and caveats, his use of anecdote and personal experience often goes beyond illustration to at least suggest that these anecdotes are evidence supporting his beliefs and practices. Like many accomplished scientists, Dr. Sinclair undoubtedly believes his perspective on a complex topic is the “right” one in most respects. Popular science literature allows him a freedom to promote his views and agenda that the strictures of the scientific literature do not. The picture he creates of the field is clear and not grossly distorted, but it very much takes his perspective, and there are plenty of elements other experts in the field would take issue with. As far as specifics, the review of the aging field and some of the main theories of aging is clear and readable. Dr. Sinclair is reasonably fair in his summaries, though he does editorialize and pass judgement on many of the ideas he covers. The review is clearly intended to lead inexorably to his personal ideas about aging, which is fair enough for a popular science book. He also makes an eloquent defense of the position that aging should be conceived and treated as a disease, and that the alternative view of it as a natural feature of the life cycle impedes efforts to understand and combat it. The book then reviews some of the longevity-promoting interventions that have been studied in animal models, such as caloric restriction and drugs like rapamycin and metformin. This section tends to emphasize the positive and gloss over the limitations and uncertainties of many of these interventions, and the general reader is likely to come away with an erroneous sense that we already have clearly effective anti-aging therapies that we should reasonably be using in humans. This is exacerbated by Dr. Sinclair’s descriptions of using various interventions himself and for his family members. While he makes appropriate caveats about anecdote and evidence, there is no question that he believes he and his relatives have benefitted from using treatments not adequately tested in humans. His enthusiasm and credentials are very likely to convince some readers that they should follow his example regardless of the lack of evidence. It is understandable that when someone believes they have found a powerful health-promoting practice that they would want to share it with others, but this sort of promotion of insufficiently tested practices is a hallmark of pseudoscience. It is problematic for a legitimate scientist to promote untested therapies using tactics associated with the promotion of pseudoscience, not only because it may lead people to adopt unproven and potentially unsafe practices but because it makes the demarcation problem worse and diminishes the standing of science and scientists as sources of reliable guidance. The latter sections of the book lay out a very optimistic view of the potential for geroscience research to extend healthspan and lifespan. There is always a tension between hope for the potential of scientific research in a particular field and recognition that many hard problems are truly hard to solve, and that a surprising proportion of good ideas turn out to be wrong. Dr. Sinclair errs, if it can be characterized as an error, on the side of exuberance and optimism. This seems a natural feature of his temperament, and it certainly fits with the desire of any researcher to present their area of expertise as likely to be fruitful, even world-changing. A different balance between creative and critical thinking, skepticism and hopefulness, can be struck in this domain, as in any other area of rapidly growing and changing scientific knowledge. I would be inclined to be more cautious about my speculations than Dr. Sinclair chooses to be. The future, and the data, will be the final arbiter of how much optimism about the field as a whole, or specific hypotheses in it, was justified. It is easy to see, however, why some of Dr. Sinclair’s colleagues feel his enthusiasm sometimes goes too far. I appreciated Dr. Sinclair’s discussion of the potential negative impact of pursuing increased longevity for humans. It is an issue everyone in the field should give serious thought to. Again, his answers are exceedingly optimistic and rely on a confidence in technology and human behavior to save us from the potential consequences of our discoveries that I find hard to support with the evidence of history. Still, a popular science book is most often an opportunity to make a case for one’s own perspective on a subject, and I cannot fault him for doing so even if I am not entirely convinced by the case he makes. Overall, Lifespan is an enjoyable read and contains a lot of effective and accurate explication of key concepts and findings in longevity science. It often promotes a distinctive perspective that may well not be shared by other experts in the field, but not usually in a way that involves gross misrepresentation of the facts. Dr. Sinclair clearly prefers optimism to skepticism, and his portrayal of the state of geroscience is likely to lead many readers to see our ability to alter human health and lifespan as far more advanced than it actually is. Dr,. Sinclair is entitled to shape the narrative of geroscience in his book to fit his own optimism and enthusiasm. However, when he uses anecdotes and references to his credentials, rather than reliable, relevant scientific evidence, to influence readers to accept this view, I think he does edge into the territory of snake oil salesmen, at least in his methods. The line between genuine and fair optimism and misleading salesmanship is a narrow one, and Dr. Sinclair treads right along it, wobbling to either side throughout the book. I would still recommend reading Lifespan, but as always I would encourage a skeptical, critical reading balanced with other sources, some of which I will review in the future. Book review: Lifespan (David Sinclair) - Gaby Mora Book review: Lifespan (David Sinclair) Lifespan: Why We Age – and Why We Don’t Have To is a remarkable book by Harvard professor David Sinclair. Sinclair postulates that aging is a disease and can be “cured” by activating the right pathways. The author David Sinclair is a Sydney-born biologist who earned his Bachelor of Science and PhD at the University of New South Wales (NSW). He is now a professor in the Department of Genetics and the co-director of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School. He also has a lab in his alma mater UNSW. His work focuses on aging and how to slow it down or even stop it. This includes the study of molecules such as resveratrol and nicotinamide adenine dinucleotide (NAD), and proteins such as sirtuins, all of which have roles in longevity pathways. Sinclair does not fall into the “technology is not natural” trap, and thus is involved with several biotechnology companies. He is also co-founder of the journal Aging. Lifespan: Why We Age – and Why We Don’t Have To David Sinclair authored this book with writer Matthew D LaPlante to translate the science into a very approachable book. I think having a background in science will help understand all the content more easily, but I don’t think it’s mandatory. I’m glad I bought the audiobook because: It’s narrated by the author It contains in-between-chapter bits where Sinclair and his co-author exchange thoughts that came up during the process of writing this book Part I: What We Know (The Past) The book starts off with the author’s childhood in Sydney’s Northern suburbs and how her relationship with her paternal grandmother and his mother’s death spiked his interest in aging. To me, the highlight of this first part is the explanation of how information is stored in our bodies: digital data (the genome) vs analog data (the epigenome). This analogy works because, as explained by Sinclair, analog information degrades over time. Similarly, changes in the epigenome are what cause aging. The second analogy is that of a demented pianist, who progressively starts playing off notes (DNA breaks) during a concerto. The piano (the genome) is not the problem, but the pianist (the epigenome) is. Occasional off notes may not noticeable but when they happen more frequently, they become an issue. Same with aging. In this part Sinclair also introduces the genes and molecules related to longevity: sirtuins, mTOR and AMPK, all of which are activated by biological stress. Sirtuins are conserved in all species and are part of a survival circuit. In mammals, they have an important role in many processes, including cell division, DNA repair and glucose metabolism. The author also explains how hormesis works to activate those same pathways, and that it can be achieved through some types of exercise, intermittent fasting, low protein diets and certain molecules. NMN is a precursor of NAD that might have a similar effect to exercise. Most people treat aging as a normal part of life, but the author postulates that aging is a disease. It deteriorates our fitness and physical resilience, and it’s the main risk factor for most diseases. Part II: What We’re Learning (The Present) In this section of the book the author explains which interventions have been proven to correlate with longer and healthier lives. These include caloric restriction, intermittent fasting (including time-restricted feeding and fasting-mimicking diets), animal protein restriction, moderate exercise, high intensity interval training (HIIT) and extreme thermic exposure (e.g. exposure to cold, use of saunas). He also talks about exposure to chemicals in the air, plastics and radiation as causes for DNA breaks. This section also mentions the compounds that have been discovered to have an effect in aging: rapamycin, metformin, resveratrol and nicotinamide mononucleotide (NMN, a precursor of NAD). Note that there are caveats with each molecule taken as a supplement, which I will not cover in this review. Another topic in this part of the book is the discovery of methylation of DNA as an indicator of biological age, as well as the controversies around gene editing, such as designer babies. Another big topic in part II is the promising applications of gene sequencing, including the ability to detect diseases before symptoms arise and the potential use of wearables for telling us what we should eat to balance our nutrient status. Although Sinclair is an optimistic guy, and gets flack for it, he ends up on a sombre note quite accurate for the times. He says he’s sure a virus similar to influenza will mutate and kill 50%+ of the population who gets it, which will happen just by touching a doorknob. I don’t think this is meant to be a fatalistic premonition, but rather a warning of what back when the book was written was yet to come. Part III: Where We’re Going (The Future) The phrase that summarises the author’s view on the future is “knowledge is multiplicative and technologies are synergistic”. As mentioned before, Sinclair is an optimist. He acknowledges we have surpassed the Earth’s carrying capacity but that the problem is not just overpopulation, but consumption and waste. He also postulates that an older population wouldn’t represent a burden to the economy if it stays healthy and can continue being useful to society. A couple of quotes from this last part that summarise what the author postulates are “aging is not just a disease but it’s the mother of all diseases” and “most people are not afraid of losing their lives, they are afraid of losing their humanities”. David Sinclair finishes off this book by sharing what he does in terms of supplementation, diet, exercise and other lifestyle habits. More information Click here to learn more about Lifespan and click here to learn more about David Sinclair’s work head. In addition, I recommend checking out the following YouTube video: Gut Health for Longevity | Dr. David Sinclair & Serena Poon | Optimize Longevity Optimize Longevity 3.1K subscribers Subscribe 154 Share 3,788 views May 12, 2023 #DavidSinclair #OptimizeLongevity #Serenapoon 👓 Join the Optimized Longevity community to get EXCLUSIVE notes and content straight into your inbox: https://bit.ly/3xHjpxh Welcome back to “Series Two” of conversations to Optimize Your Longevity! In this next set of conversations, Dr. David Sinclair and I dive into practical advice that you can easily implement into your daily life. The theme of these conversations is ”3 in 30,” aiming to give you three tangible takeaways in thirty minutes or less! Discover how to optimize your longevity and improve your well-being with Dr. David Sinclair and Serena Poon in this second episode of the Optimize Longevity series. In this conversation, we explore the emerging field of gut health research and its critical role in optimizing your vitality. Learn how prebiotics, probiotics, and postbiotics support immunity, mental health, cognitive function, and more as you age. Dive into the science behind regular eating windows and intermittent fasting, their effects on gut health, and how it all impacts longevity. Don’t miss this must-watch episode! Timestamps: Intro 00:00 Why gut health is important for our brain health 01:41 What is a microbial? What is in our microbiome? 03:09 Gut and brain connection 04:51 What bacterias we need in our microbiome 06:08 What is prebiotic, probiotic and postbiotic? What do they do and what is the difference? 08:33 Kids who don't have great microbiome have this 12:31 How would you know if you have a poor microbiome? 12:45 Fermented foods for your gut microbiome support 14:16 How fasting affects our microbiome 14:36 What is a bad microbe 16:02 How you test your microbiome 16:46 David speaks about his gut microbiome journey 18:04 Bacterias you want to have in your microbiome 19:49 Can you get benefits from yogurt or you need to take supplements as well 21:06 Poor gut microbiome can result in these health problems 23:01 Gut disease and lifespan 24:30 Leaky gut and what issues it can cause in your body 26:06 If you are going vegan, what to pay attention to 27:14 Positive side effect of a plant-based diet 29:45 ---------------------------- About your Optimize Longevity hosts: Dr. David Sinclair, A.O., Ph.D. | Harvard Professor & Author of NYT best seller Lifespan Serena Poon, CN, CHC, CHN | Celebrity Chef, Nutritionist, & Expert in Longevity Wellness Tik Tok Optimize Longevity https://www.tiktok.com/@optimizelonge... Bringing you tips for improving the quality of your life, while also extending your lifespan! #OptimizeLongevity #DavidSinclair #Serenapoon Basic SUPPLEMENT PROTOCOL 2023 Update | Dr David Sinclair Reverse Aging Revolution 50.7K subscribers Subscribe 1.2K Share 26,055 views May 15, 2023 #PQQ #Quercetin #berberine Dr David Sinclair talks about his view on the future of aging and also update on his basic supplement protocol in this clip. Please note that the links below are affiliate links, so we receive a small commission when you purchase a product through the links. Thank you for your support! =*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*= ~* ~ ProHealth Longevity 15% OFF Discount Code : REVERSE https://www.prohealth.com/discount/RE... NMN Pro500 Caps https://prohealth.pxf.io/NMN500 Trans-Resveratrol 500mg Caps https://prohealth.pxf.io/TransResvera... Berberine Pro 600 mg Caps https://prohealth.pxf.io/Berberine Fisetin Pro 125mg https://prohealth.pxf.io/Fisetin Arctic Select Krill Oil™ 1g softgel https://prohealth.pxf.io/KrillOil ~*~ DoNotAge Supplements 10% OFF Discount Code : REVERSE https://donotage.org/ref/Reverse/ Pure Spermidine 8mg Caps https://donotage.org/product/pure-spe... Pure Vitamin D3, K2 & Magnesium https://donotage.org/product/pure-vit... At Home NAD Level Test Kit https://donotage.org/product/at-home-... ~* ~ Restore Our Cells Ability To Make NAD - Nuchido Time+ Supplement ~*~ FIRST ORDER 20% Discount Code: REVERSEAGING20 https://www.nuchido.com/REVERSEAGING ~*~ iHerb New Customer 20% OFF code: NEW20, existed customer 5% off Discount Link https://iherb.co/sUBAZcqw =*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*= David Sinclair is a professor in the Department of Genetics and co-director of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School, where he and his colleagues study sirtuins—protein-modifying enzymes that respond to changing NAD+ levels and to caloric restriction—as well as chromatin, energy metabolism, mitochondria, learning and memory, neurodegeneration, cancer, and cellular reprogramming. Dr David Sinclair has suggested that aging is a disease—and that we may soon have the tools to put it into remission—and he has called for greater international attention to the social, economic and political and benefits of a world in which billions of people can live much longer and much healthier lives. Dr David Sinclair is the co-founder of several biotechnology companies (Life Biosciences, Sirtris, Genocea, Cohbar, MetroBiotech, ArcBio, Liberty Biosecurity) and is on the boards of several others. He is also co-founder and co-chief editor of the journal Aging. He is an inventor on 35 patents and has received more than 35 awards and honors. In 2014, he was on Time Magazine’s list of the “100 Most Influential People in the World,” and listed as Time's Top 50 in healthcare in 2018. Dr. Sinclair’s official lifespan podcast / davidsinclairpodcast . ___________________________________________ DISCLAIMER: Please note that none of the information in this video constitutes health advice or should be substituted in lieu of professional guidance. The video content is purely for informational purposes. #DavidSinclair #NMN #d3k2 #spermidine #berberine #reverseaging #supplement #oskgenes #slowaging #resveratrol #stayyoung #EGCG #NMN #VitaminB12 #MethylDonors #TMG #Epigenetic #sirtuin #NadBooster #Exercise #NAD #BeingHungry #NMN #Rejuvenate #Reprogramming #Mitochondria #ALA #Metformin #PQQ #CoQ10 #Carnitine #Antioxidant #LookYounger #NMN #Resveratrol #Quercetin #Fisetin #senolytics #OliveOil #Sirtuin #HIIT #aging #Lifespan #NMN #NR#Metformin #Berberine #ReverseAging #Epigenetic #OleicAcid #NMN #NAD #Sirtuins #Fasting #Longevity #RestoreYouth #Reprogramming #DavidSinclair #DrSinclairLab #Healthspan #Younger #antiaging #DrSinclair #NAD #longevity #Bioscience #Epigenome Music SONG First Dream ARTIST Brian Bolger ALBUM First Dream LICENSES Get YouTube Premium Music 102 Comments rongmaw lin Add a comment... Reverse Aging Revolution Pinned by Reverse Aging Revolution Reverse Aging Revolution 5 days ago (edited) ~* ~ ProHealth Longevity 15% OFF Discount Code : REVERSE https://www.prohealth.com/discount/REVERSE NMN Pro500 Caps https://prohealth.pxf.io/NMN500 Trans-Resveratrol 500mg Caps https://prohealth.pxf.io/TransResveratrol Berberine Pro 600 mg Caps https://prohealth.pxf.io/Berberine Fisetin Pro 125mg https://prohealth.pxf.io/Fisetin Fish Oil - Arctic Select Krill Oil 1g softgel https://prohealth.pxf.io/KrillOil ~*~ DoNotAge Supplements 10% OFF Discount Code : REVERSE https://donotage.org/ref/Reverse/ Pure Spermidine 8mg Caps https://donotage.org/product/pure-spermidine/ Pure Vitamin D3, K2 & Magnesium https://donotage.org/product/pure-vitamin-d3-k2-magnesium/ 7 Reply 1 reply Sloane Autumn Sloane Autumn 5 days ago I started taking NMN in January. I went back to get my prescription renewed and my vision has actually gotten better. I’m 43 and it’s only stayed the same or gotten worse since forever. I do also feel so much better and have a lot more energy. 11 Reply 1 reply Boossers Garage Boossers Garage 5 days ago (edited) it's been working for me. started a year ago, added NMN a month ago, I already feel 10 years younger. my gray hair is not so gray anymore, my eyes are actually getting better. I'm not stopping. 20 Reply 12 replies Dino Merino Dino Merino 4 days ago He is the guy who got everyone crazy over NMN lol. At first I was sceptical but after doing some research on the subject I got hopeful and excited, fast forward today I am taking AEON NAD+ and boy how energetic I've become. Btw I am 77 years old this year 2023. 9 Reply 1 reply Rona Jiki Seri Rona Jiki Seri 21 hours ago (edited) Thanks Dr. David Sinclair for sharing this unique benefits of lifestyle. Thanks Almighty for his input into your knowledge. I am also turning 54 soon. Will try this supplements. God bless you and family❤❤ 1 Reply Coco’s Tube Coco’s Tube 1 day ago I’m not sure why everyone is hating on him! He is saving everyone from diseases. He’s teaching you to be mindful of your health. He never pushed any product he is simply finding solutions ONLY FOR THE PEOPLE WHO CARES ABOUT THEIR HEALTH! So they can live longer and spend more time with their love ones! Start appreciating and stop complaining. 7 Reply 1 reply C Ski C Ski 1 day ago I’ve been taking berberine before meals for about 3 months. I’ve low 5 lbs even though I didn’t need to lose weight but I feel great! Belly fat has lowered too. 1 Reply Pramuji Singgih Riyanto Pramuji Singgih Riyanto 5 days ago You are awesome, Mr. Sinclair. You really inspire me a lot. Love your podcast. 9 Reply 1 reply Harry Harry 4 days ago A real salesman. 1st a salesman then a scientist 11 Reply 1 reply Jerry Jerry 2 days ago Lot of uninformed commenters here that are evidently not aware of Sinclair's recent attempts to have NMN reclassified from a supplement to a drug and pulled off the market, to be replaced by (wink wink) his company's new NMN 'drug', for which he has also filed a patent. This guy's all about the money, regardless of how kind and concerned he comes across in his videos and interviews. 7 Reply Models 2 Watch Models 2 Watch 5 days ago The hands of Time + Staying Young + Modern Miracles Reply ΆΝΝΑ ΚΛΑΟΥΝΤΙΑ ΜΙΧΑΛΤΣΕΑ ΆΝΝΑ ΚΛΑΟΥΝΤΙΑ ΜΙΧΑΛΤΣΕΑ 5 days ago Very emotional in the beginning ... his voice was trembling. Love ya prof. Sinclair. 🤗 6 Reply 1 reply No No No No 1 day ago NMN is pretty amazing. Definitely works. 3 Reply Kevin San Mateo Kevin San Mateo 1 day ago He really nailed those speeches...too bad this is the same exact speech weve heard the last 30 years 😳 2 Reply Mike VB Mike VB 5 days ago Dr Sinclair is a year younger than me. He looks as good as some his age (but not many). Keep up the good efforts Dr S. 2 Reply 4 replies A-A-Ron A-A-Ron 5 days ago What's your feelings on nicotinic acid vs nmn? 2 Reply Frederick sappor Frederick sappor 5 days ago Dr Sinclair, what brands of supplements do you take? Any clue? Thanks 1 Reply Elliott Rubenstein Elliott Rubenstein 4 days ago I’m 77 and have taken MNN etc. for over three years. See you all on the other side in 43 years. Shalom. 4 Reply 1 reply Alice Maarouf Alice Maarouf 5 days ago I hope you enjoyed your time in Abu Dhabi Dr.David . 3 Reply Manuel Ojeda Manuel Ojeda 4 days ago I take NMN and FISETIN and AKG plus TMG plus MCT oil. I don't wear eyeglasses either. 2 Reply vladimir vladimir 5 days ago what does the doctor think about molecular hydrogen? 2 Reply JC Yumei JC Yumei 5 days ago 👍👍Fantastic! 💖💖 2 Reply Dave Whaley Dave Whaley 5 days ago What about a supplement called, ca akg? I’ve read that it works well for anti aging 13 Reply 3 replies Mike Lance Mike Lance 5 days ago Don’t forget Beta-alanine and activated charcoal 2 Reply Barzin Lotfabadi Barzin Lotfabadi 5 days ago Just beautiful. 2 Reply Emil Emil 2 days ago I don't get one thing, they promote NMN, NR and take anourmous money for it, but NAD levels can be increased even better with simple Nicotinamide and other vitamins Bs. That's the business where people follow 1 guy who say what 'he does', the only proper way of increasing life. And also remember to buy Resveratrol ofcourse and take NMN and Resveratrol 1 gram each ! Ehhh 3 Reply Richard Nunziata Richard Nunziata 5 days ago It's a shame he has any relation to the company involved on pushing the FDA to make NMN not a supplement...this is against all our interest. 18 Reply 3 replies pramod sharma pramod sharma 4 days ago in bhrigu valli meaning of rig vedic mantra satyam jnanam etc explained as Brahman is truth .knowledge has also elaborately explained in part on bliss . it meant ..He enjoys as identified with the all knowing Brahman all desirable things simultaneously .Brahman vedanta god same in gita described as Atma or Self . 1 Reply C Ski C Ski 1 day ago Try the Nitric oxide Dump exercise. You will feel amazing! Reply Seeker Seeker 5 days ago Let's hope he's right. 1 Reply TheVodec TheVodec 5 days ago Who knew that diet and exercise lengthened health span? 9 Reply 2 replies Mark van der Rijt Mark van der Rijt 5 days ago Interesting.. i wonder though..If everybody stays young forever, can you imagine what will happen to the worlds population? Or will the anti aging magic only be available for the happy few? 2 Reply 3 replies Sylvain Auclair Sylvain Auclair 11 hours ago But... he wants NMN not be accessible any more. 1 Reply Hunza the beautiful valley Hunza the beautiful valley 1 day ago 🎉🎉🎉🎉for you 1 Reply Dave 24-7 Dave 24-7 4 days ago I guessed his age to be 70 I googled to find out he’s only 53, oops 1 Reply Angela Davies Angela Davies 5 days ago I hear after 50 ubiquinol is necessary? 1 Reply Gregarious Antithesis Gregarious Antithesis 5 days ago He is but a 16 year old boy man but now slowly reverting to his pre pubescent self. 1 Reply 1 reply Old Gray Beard Old Gray Beard 3 days ago What about ISRIB? Reply amma Lea laura amma Lea laura 5 days ago Danke Reply Elizabeth K Elizabeth K 1 day ago If you're too lazy to eat healthy and exercise regularly... just pop a pill... I don't 5hink you deserve to have the benefits as 5jose who do the work. 1 Reply The Ancients Ancients The Ancients Ancients 5 days ago He is trying to con and Arab money 💸💰 now 😂 7 Reply Ritsuko Hair Salon Ritsuko Hair Salon 17 hours ago Good sales pitch. He is going to have nmn banned in Arab countries as well. Reply Ar Ar 2 days ago With all due respect. He is 54 and looks like a 54 year old. 7 Reply 3 replies montaque montaque 5 days ago What interview is this? Reply Ruud VD Ruud VD 4 days ago He looks older than his chronological age……… 5 Reply Gur Avi Gur Avi 4 days ago He's an embryo Reply Richie Kock Richie Kock 4 days ago 54-ish. He looks his age. nothing young about him. 7 Reply 3 replies Spyros S Spyros S 5 days ago Snake oil salesman 10 Reply 4 replies neko nekic neko nekic 4 days ago he does look 54...i don't get the fuss? 4 Reply 1 reply Juli yoo Juli yoo 4 days ago Honestly he looks 57 or 59 4 Reply 如何逆轉老化、變得更年輕？哈佛頂尖科學家的驚人發現｜《可不可以不變老？》 下一本讀什麼? 43.9K subscribers Subscribe 7K Share 256,560 views May 11, 2023 #讀書心得 #好書介紹 #說書推薦 《#可不可以不變老？》的作者是哈佛醫學院遺傳學終身教授大衛．辛克萊（David Sinclair），他是世界首屈一指的科學家和企業家，曾經被選為《時代》雜誌最有影響力的百大人物。他最廣為人知的學術成就，就是研究「人類為什麼會老化」以及「如何逆轉老化」。在這本書中，他從科學的角度探討了老化的原因、如何通過現代科技和改變生活方式來延長自己的壽命。 00:00 本集概述 00:52 這本書在說什麼 02:57 從生命起源說起 06:59 老化是因為資訊遺失了？ 10:29 延緩老化的方法 14:20 本集結語 17:30 瓦基推薦下一本讀什麼 博客來 25 元優惠券：https://activity.books.com.tw/crossca... 📝部落格文字版： 《可不可以不變老？》讀後心得：活得愈老卻活得更好 https://readingoutpost.com/lifespan/ 📚我讀過的其他好書，以及閱讀習慣的培養 2022 年瓦基最喜歡的 10 本精選書單 https://readingoutpost.com/2022-favor... 2021 年瓦基最喜歡的 10 本精選書單 https://readingoutpost.com/2021-favor... 養成這3個習慣，一年讀50本書改變人生軌跡 https://readingoutpost.com/how-to-rea... 喜歡看別人的讀書心得？愛書人50個私藏去處 https://readingoutpost.com/book-lover... 🎧收聽 Podcast 說書節目「下一本讀什麼」 Apple Podcasts https://apple.co/34gUy39​ Spotify https://spoti.fi/3i71G70​ 📚關於書評部落格「閱讀前哨站」 訂閱免費電子報 https://readingoutpost.com/book-picki... 每週二和每週五準時收到：一篇閱讀筆記、兩則好書金句、一個激發思考的問題。 傳送門連結（訂閱追蹤、與我聯絡、業配折扣專區） https://readingoutpost.com/bio #讀書心得 #好書介紹 #說書推薦 #書摘濃縮 #閱讀筆記 Chapters View all 283 Comments rongmaw lin Add a comment... Kevin Lu Kevin Lu 16 hours ago 延緩老化的方法 一.偶爾[刺激生存迴路]來修復身體 1.少吃一點點-間歇性禁食 ex. 168飲食法 52輕斷食法 2.規律的運動 3.低蛋白飲食 4.洗冷水澡 5.泡熱溫泉 二.透過藥物或醫學治療來[避免資訊流失] 26 Reply 7 replies 楊政峰 楊政峰 1 day ago 我是生物背景的，也喜歡寫作，目前出版了五本書。深刻覺得台灣閱讀風氣極為低落，無意間逛到這個閱讀的網站，還有年輕一輩的朋友願意分享閱讀經驗，很不錯。 51 Reply 下一本讀什麼? · 3 replies 斑 宇智波 斑 宇智波 1 day ago (edited) 2008年國中時候我也有這種想法，老化只是一種不正常的基因表達而已，依據是海拉癌細胞一直活著。高中時候已經非常注意高強度運動和清淡飲食 6 Reply 心理学与催眠 心理学与催眠 1 day ago 我已经73岁了，还在工作，比很多50岁的人还显年轻，所以我认为增强生命力是不需要任何药物的，最重要的就是充满快乐幸福感。 183 Reply 下一本讀什麼? · 25 replies Love Fantasy Love Fantasy 1 day ago (edited) 我自己是一個好神奇的例子 好多人也猜不出我 或我媽媽的年纪 我在30歲突然再長高兩吋 皮膚一直像十多歲的人 唱歌老師說我聲線從沒老化過一樣 過幾年我都快50 但也沒有白頭髮 記憶力超強 在幾年疫情也沒有病過 而我今天有幸看到此影片 我很認同他的說法 因為我過往很多年很巧合下 都有著少吃 多運動 每天記錄自己營養 冲凍水凉 早睡 常常心情好的習慣 而且心境都比年輕人年輕 所以我相信以上種種原因真的讓人延缓衰老的 很多谢片主分享了這些這麼重要的訊息 ❤ 感恩 63 Reply 下一本讀什麼? · 29 replies gary530 gary530 3 days ago 少吃（有飢餓感 吃食物原型 低碳） 多運動（走路 肌力訓練）洗冷水 每天曬30分太陽 最重要是隨時保持愉悅心情！ 173 Reply 4 replies 沛然有雨 沛然有雨 3 days ago 要做到深入淺出且兼顧事實是很精力的，喜歡這種把艱澀內容吃下去再白話文解說的體貼。 25 Reply 愛玲 廖 愛玲 廖 5 days ago 感謝瓦基的分享，長生不老這個想法，我三十歲的時侯就想過了 ，隨著人生起浮挫折以及身體的遺傳基因疾病也隨著自己建康有狀況和家人的年齡變大，身體的病痛變多而讓我在邁入五十一歲的中年更加在乎這個如何讓自己和深愛的親人長生不老，甚至不死，我每天都在思考著這個無解的答案，好在我國中的生物學的不錯，心理學也是，所以一直很想要知道任何跟生物醫學延長老人家的生命的求知慾很強，我以前想過自己的爸媽都邁入八十歲，那自己應該是能活到一百歲，現在網路上資訊很發達，我又注意到連沙烏地阿拉伯這個國家都在硏究如何長生不老的醫藥，英國科學家們也證實人類可以在未來有機會透過藥物醫療活到兩百歲，這些科學家的學術硏究資料讓我對自己和未來的生活充滿了 希望和想像，可以說是我現在追逐的目標和夢想，就是讓自己和身邊所愛的家人幫助他們延年益壽，身心靈建康長壽，平安也很重要 ，所以我還想要當千年老妖精，專門吃壞男人色鬼的肉，這是我的夢想，而且我會不計一切代價勇敢的去追求，因為我很愛我的爸爸，他是全世界全宇宙除了我兩年前往生的愛犬忠狗 吉米之外最疼我的人，甚至願意付出生命危險救助我的人，當我躺在醫院一個月每天吊著點滴吸氧氣鋼瓶的時侯，願意出錢七千元醫藥費來治療我的好爸爸，沒有我爸爸半夜三更送安眠藥來給我吃，我差點休克死亡，喘不過氣，當然也感謝醫院裡的護士和志工阿姨的照顧，把我的小命救了回來，現在我每年都很注意醫院打流感疫苗的時間，也會想要提醒身邊的家人朋友一定要去打流感疫苗，因為這個病毒細菌和新冠病毒一樣會制人於死地，而且快速會讓你失去生命，如果你沒有金錢和保險，就得不到醫院自費最好的醫療，所以我很重視健康，因為身心的健康也關係到你的外表皮膚的美麗，使用 好的保養品和認識好的產品介紹人都是一件很重要的事，所以我想請問一下這本醫療書籍在那裏可以訂購買到？ 博客來而已嗎？感恩回覆，謝謝， 20 Reply 9 replies ami ami 4 days ago 生命力比長壽更重要👍 48 Reply A. Lavender Chen A. Lavender Chen 3 hours ago I agree with the gentleman who is 73 and continuously enjoyed working. To me: Positive mental attitude, deep meditation, close relationship with GOD and nature, yoga, deep breathing, healthy vegs and fruits, fun hobby, fitness and weekly social activities. I have been working with a fitness trainer at my GYM for 2 months from one day to two days weekly. Gratefully, my energy has been upgraded that my goal is to be 38 again. I am 68 and I am renewing my life to be active this year. I work in the care management community continuously. I do plan to semi retire when I am 80. 😅 Reply 紫羅蘭 紫羅蘭 3 days ago 很有學問和休養的主播👍 13 Reply May Lee May Lee 6 hours ago (edited) 約55岁时发现自己长高了1公分,大概2年之后又增加多两公分。期間生活起居飲食如常。同时体重也让自己有些难看了,真的是長大長高了,就开始168食法。168至今2年多來也只掉了皮下脂肪。一切安好,感恩! 2 Reply Holly White Holly White 3 hours ago 我61，自從我吃不多時，身體檢查報告出來醫生說我的報告是100分，立刻又改口說，不，是101分。同時問我如何養生？我唯能想到的是少吃，不忌口，但內心仍有盤算。很多人評論我不照三餐吃對身體不好，我懶得辨！ 運動練肌肉是重要的。我的身材看來像30 或40. 更驚訝的是我最近經專人教導穿對胸衣尺寸從75C變75D。所以如同這本書的資訊，我們一直活在過去錯誤的觀念，而沒有正確的認知。聖經中活到5，600歲是真的。人活著要時時更新，並且要懂得節制，不論是飲食，慾念，道德皆是。我真正的快樂來自於幫助和愛動物，作環保，隨時隨地適當的助人一臂之力的互動。笑臉迎人的對每個人將快樂彼此感染。儘快的拋開負面情緒，不找人訴苦。同環保一樣，垃圾要丟但不要丟到別人家。很多老人很囉嗦愛唸，年輕人不喜歡。我卻有很多年輕人喜歡和我聊天，我喜歡跟著新時代的腳步走，向年輕人學習，不以長輩架子分享我的經驗或給予意見。了解年輕人的感覺真好！所以和女兒們如同朋友一般相處。這本書給予很好的資訊，我可以重新注意和調整自己的身心狀態。謝謝你的分享尤其以淺顯的方式表達讓我很快的了解。祝福你，己訂閱且按讚。😊😊😊 2 Reply 小四 小四 2 days ago 我58歲，5千公尺可以跑25分左右，平常出門都把臉包起來沒什麼皺紋，看了這幾我的缺點是我吃太多甜食。聽過一些長壽的老兵只吃饅頭就可以活到90多歲，以前有打過仗流大汗。已訂閱 18 Reply 下一本讀什麼? · 3 replies 老師唐 老師唐 21 hours ago 功德無量感恩分享 3 Reply 明心 明心 3 days ago 自心是最重要的，看得起自己，知道自己有能力，“我能够成功”，这就是信念。 *不针对任何人和事，仅分享善言，感恩 宽容！ 14 Reply 廖方柔 廖方柔 1 day ago 第一次看到瓦基的視頻～受益良多，內容聽起來跟現在的生酮飲食+間接性斷食挺吻合的👍👍💞💞 4 Reply 1 reply Root的遊戲心得小舖 Root的遊戲心得小舖 1 day ago 第一次看你頻道，內容說得很好face-blue-smiling 3 Reply 王阿光 王阿光 3 days ago 約1年多前看過，一言以蔽之，人活著"不要過的太爽" 60 Reply 下一本讀什麼? · 3 replies Helen Yu Helen Yu 2 days ago 講得真好👍🏻 4 Reply Cathy Lin Cathy Lin 3 days ago 這集講的很棒 贊!👍👍👍❤️❤️🙏🙏 5 Reply Shi Si Shi Si 2 days ago 很棒👏🌹感恩分享🙏 3 Reply BrianYeh BrianYeh 1 day ago 看巴菲特九十幾歲還活力十足，怎麼辦到的？1.有錢，2.有時間，3.有嗜好，4.沒人管. 22 Reply 3 replies Chiew Neo Goh Chiew Neo Goh 3 days ago 非常好好的资讯❤❤❤ 4 Reply 蘇誌盈 蘇誌盈 4 days ago 學思並進，多思惟觀察，才能獲得正確的認知，有了正確的認知，才能生活更健康更快樂，更高超的生命格局。 7 Reply The多 The多 7 hours ago 跟古人的辟穀有異曲同工之妙，道家的養生法。 另外一部分就是氣功了。 Reply Lisa Sun Lisa Sun 4 hours ago 人的老化是符合热力学第二定律的。从有序到无序，无法逆转。 Reply 智筌張 智筌張 1 day ago 你來講這本很有說服力 1 Reply Allan Lan Allan Lan 2 days ago 要延長 生命力 要有逆齡的活力才是重點 飲食 運動 作息 都是關鍵 但現在新世界來了有更輕鬆省時有效的黑科技來了 讓人們可以輕鬆逆齡 有活力。 1 Reply 3 replies 李寒風 李寒風 1 day ago 還是要透過大量人體實驗來證明，只有理念還不夠啦 3 Reply Tian Mar Tian Mar 3 days ago 我58岁的时候看起来只有30多，可进60后，老化就断崖式的，现在62虽然脸上没有纹，眼角也没鱼尾，可发际线大幅上移，明显就是60来岁的样子，不过体能还可以，四十来岁的感觉，每天工作十几个小时，电脑前有时连续10小时不休息，视力也还可以不觉眼疲劳。所以他才51，等62的时候再看。 17 Reply 下一本讀什麼? · 7 replies 太阳流珠 太阳流珠 20 hours ago (edited) 天长地久。天地所以能长且久者，以其不自生，故能长生。如果人能有像天地那样清净无为，大公无私的德行，也可以与天地共长存。 3 Reply 胡浩懷 胡浩懷 22 hours ago 很棒的一幀視頻！ 1 Reply leo c leo c 2 days ago 飲食 睡眠 運動 最重要的是 意念 靜坐 冥想 可以鍛鍊你的意識 意識力高 就可以完全控制身體的細胞 你一個念頭就能不老了 8 Reply 4 replies Michael Lo Michael Lo 1 day ago David Sinclair不完全可信, 他已經有白藜蘆醇的前科, 只是一名商人, 衰老是DNA損傷沒錯, 但表觀是高度可變的東西, 那怕你做點運動也會改變, 而OAK重編程令細胞回春也是在表觀改變之前, 所以表觀是結不是因, 只能當在代謝的程度而己, 而真正衰來是來王DNA雙鏈斷裂(DSB)而激活P53基因抑制細胞分裂所至, 而長期P53激活是多因素的, 有端粒縮短, 有rDNA縮短, 也有高DNA受損的衰老而不死的細胞引致的. 8 Reply 2 replies Eileen Eileen Eileen Eileen 13 hours ago 每天开心快乐就是良药。 Reply Steven Chan Steven Chan 2 days ago 老化说成了长期损坏而导致。 但没说老化是要一段时间，那个时间就是最关键。就是所谓如何稳住初期。因为比较容易改善。 如果到了末期，那就是所谓可能不可能 50% 50% 的说法了。 到时书本会说不是每个人都有这效果。风险自己承担。 感觉是科幻书本。 可以讲到生命来源但也直接就好像讲到能复活已去世的人阶段。 要做到别那么快老，是有个阶段开始的。那个阶段就是很重要关键。 1 Reply ABC ABC ABC ABC 2 days ago ❤說的完美 3 Reply John Yang John Yang 17 hours ago 作者最近在沙烏地，印度 及Time100的座談內容是他那本書的uodate 2 Reply 下一本讀什麼? · 2 replies killerkao1999 killerkao1999 3 days ago 平常多做好事多積功德，死後到天人道投胎，人人超過萬把歲且身體健康不會老，就怕你會覺得太無聊，又想下凡到人間嘗鮮～ 7 Reply Z L Z L 2 days ago 為什麼低蛋白飲食可以抗老？不是說増肌，或者低碳都鼓勵高蛋白嗎？ 14 Reply 6 replies lu lu lu lu 2 days ago 请问有没有办法可以改变天生的基因，有这样的书吗？ Reply 3 replies coco coco 3 days ago 長期來只聽你聲音，今天看到你的長相，果然跟聲音一樣秀氣，有氣質。 13 Reply 下一本讀什麼? · 2 replies 晴雨 晴雨 3 days ago 人因有罪才会老死 “只是分别善恶树上的果子，你不可吃，因为你吃的日子必定死！」 创世记 2:17 又对亚当说： 你既听从妻子的话， 吃了我所吩咐你不可吃的那树上的果子， 地必为你的缘故受咒诅； 你必终身劳苦才能从地里得吃的。 地必给你长出荆棘和蒺藜来； 你也要吃田间的菜蔬。 你必汗流满面才得糊口， 直到你归了土， 因为你是从土而出的。 你本是尘土，仍要归于尘土。” 创世记 3:17‭-‬19 4 Reply 2 replies Tim Lam Tim Lam 3 days ago 如果人真的可以長生不老， 那有多麼的可怕。身死不可怕，最怕活厭了又死不了。 15 Reply 1 reply Taichi Yu Taichi Yu 6 hours ago That's what I want. I'm 71 years old and people say i look about fifties, most is because i got baby face, I like to do excersises, like taichi, chikung, swimming, dancing, singing, whatever... I seldom feel tired. I like to help people within my budget and ability. Yet it's limited to my boundary, i.e. as long as my health permits. Empathy, kindness, peace, learning, are helpful to maintain one's mindset. I appreciate the author and the person who share this unique and advanced, unexplored idea to me and the whole world. I'll certainly share this video to all my family members, friends, from juniors to seniors. 1 Reply Hui Peng Hui Peng 28 minutes ago 这本书有没有中文版，谢谢 Reply 劉得滑 劉得滑 1 day ago 您說的好詳細,訂閱 1 Reply Gary Lin Gary Lin 17 hours ago 這個標題衝流量一流😂👍 2 Reply J. W. J. W. 2 days ago 谢谢分享！！！ Reply Silly Fool Silly Fool 6 hours ago 好想知這本書的作者現在樣子是怎樣的？ Reply Yuehua Xiang Yuehua Xiang 4 days ago 谢谢分享！ 2 Reply isa chin isa chin 2 days ago 長大後 壓力大 忙來忙去 睡不夠 飲食不正常，就老了 9 Reply 劉海藍 劉海藍 3 days ago 非常感謝。 2 Reply G L G L 4 days ago 可能喔,我通常都吃八九分飽,不是為了減肥,只是飲食習慣,很多人都說我看起來很年輕~ 17 Reply 3 replies Good Sun Good Sun 2 days ago 從網路裏看到人類吸氧，基因也被改過，是人類易老化的原因之一二。現在的人要提高維度，提高精神層次，可以做的就是改變飲食方式。人類現在的飲食方式是造成老化和疾病的主要原因。飲食科學需大家來共同研究。 5 Reply 1 reply Ren Hang Ren Hang 3 hours ago (edited) 年轻时长壮快，老时衰得快。 年少高挑幼相，老时长得秀。 1 Reply horn213 horn213 1 day ago 看了一下 吃得少 多泡熱水 規律運動，低蛋白飲食，難怪日本人長壽😂 4 Reply MrPathorock MrPathorock 2 days ago 古代人的生活习惯绝对比现代人要健康吧，吃的也少，没有空调每天都要走路，可是古代人的寿命比现代人短多了。 9 Reply 3 replies Jason Lin Jason Lin 2 days ago 沒錯.活得健康比活的久重要..雖可逆轉老化、變得更年輕, 但還有一個前提是..可能需準備很多$吧~~所以,以後是富裕程度決定生命長度? 5 Reply 1 reply Jeffery Tseng Jeffery Tseng 3 days ago 四百多頁的書只得到斷食和運動的結論的話，那真的……可以不必看了，已經是很久前的學術理論。 13 Reply 1 reply Lexi Lexi 1 day ago 按Sadhguru 的说法，长寿不是百岁而是84岁 Reply 小邊 小邊 2 days ago 『抗老化，你需要大重量訓練」，看一下這本書吧。 5 Reply 下一本讀什麼? · 3 replies 王繼志 王繼志 3 days ago 從外表看，你絕對是長壽一族。 3 Reply JPL JPL 10 days ago 他現在已經是一個純粹的商人了 10 Reply 1 reply THAM PEK SUAN THAM PEK SUAN 4 days ago 第一次刷到这个视频，内容很好，订阅了。 6 Reply eileen chang eileen chang 1 day ago 我也隱約感覺到舒適圈待著愉快，但好像對生命活力不是很有利 1 Reply 冰台行者 冰台行者 1 day ago 节目真好 2 Reply 心目 心目 2 days ago 如果長生不老的話, 那地球人口會是如何, 基本的民生物質會充分供應嗎?這應該會像是高密度的老鼠一樣, 為了食物會是如何, 人口會增加卻沒人會死去, 想想是什麼恐怖現象. 科學界還不如去研究如何呼風喚雨能為人所控來的更造福人類. 2 Reply 3 replies Alex Hong Alex Hong 1 day ago 不知道書上有沒有說為什麼要低蛋白。不是都說要低澱粉飲食才不會變胖，尤其是精緻澱粉對人體也不好，如果低蛋白飲食，那麼澱粉類不就要增加了嗎？還是要強調的是食物不要吃太多，六分飽就好 2 Reply 2 replies Catherine Han Catherine Han 2 days ago 任何疾病，都是業報 ~ 有自己的(累世造的，得逐個還)，也有共業(家人、國家…造的業)。。。往往不是單靠藥物、運動、養身就有用的 尤其西藥研發的返老藥物，都只看身體的一部份，那你加速部份功能的新陳代謝，不就加速其他官能的過度老化 ~ 一個機器，你只注意改善年輕化某個功能，其他部份必得過度工作配合，那不就整體毀得更快？？？ 要不老化，首先一定要吃素的，不傷害他人和動物生命(包括不能墮胎)，佛教的五戒 ~ 不殺生(包含全素)、不偷盜、不邪淫、不妄語、不喝酒~ 就是最最基本的保護網，大多數人都如此良善的話，未來或許有可能大家都沒有老病苦了，除了過往做過太大的壞事的人，於當世必得受報之外。。。。。業力很可怕的，業力一來，還或許一下馬上老10歲以上呢！ 13 Reply 4 replies 心理学与催眠 心理学与催眠 1 day ago 很多人会认为我一定是过着养尊处优的生活，其实完全相反，只是我无欲无求，凡是顺其自然而已。 2 Reply 1 reply Jack Lin Jack Lin 10 hours ago 40億年前，怎麼會突然出現了一個細胞呢??? Reply Crochet Crochet 1 day ago (edited) 長命百歲也要有足夠的金錢來供養呢。不然的話六十七十八十歲也要去打工嗎？這樣不退休的話年青人就更難找到工作了。如果退休政府供養的話。國家就要破產了。每個人都長生不老的話。其實不需要逆轉年輕 衹要身體健康就是了。就如你所說沒有人體實驗的基礎下作出的結論。而且個人基因體質遺傳各方面也會有影響的吧。例如他提倡要吃的補充劑市面上就與他的理論作為基礎大行其道，賣廣告。讓消費者誤以為吃了就能長生不老。而且價錢還是非常之昂貴。但事實上普通的補充劑也有一樣的成效。分別在他說的轉化前和轉化後。價錢就是幾百倍的分別。 3 Reply Kuang-Hsien Cheng Kuang-Hsien Cheng 2 days ago 自信 自在 愉悅 無可就藥的樂觀主義者 才是王道 DNA是可以透過意識心的力量改便的 健康的三大定律是： 一 身體天生健康 二身體有很強的自癒力 三身體是心靈的一面鏡子 沒有這些正確觀念 對自己身體負面評價 正是健康走下坡的最重要原因 老化不是必然現像 君不見 九十歲多還活龍一尾？ 少量多餐 分段睡眠 是健康的方法 身心靈醫師 3 Reply Nana T Nana T 10 hours ago 什麼叫做生物本科生啊？ 我長這麼大了，也是唸生物/醫學相關的，可是從來沒聽過這個字耶！ Reply 建雄 郭 建雄 郭 19 hours ago (edited) 抽菸、喝酒..很會催人老，你看抽菸者的皮膚，飲酒者的酒空眼睛..就證明了。還有腦部的傷害.. 1 Reply Lab. Lab. 3 days ago 0:07 聽成「可不可以變老」，嚇到繼續聽😂 2 Reply 1 reply Adam Adam 1 day ago (edited) 想慢点变老少做有氧运动，比如长跑 Reply Gang Yu Gang Yu 1 day ago 怎么才能买到这本书？ Reply WenChin Chou WenChin Chou 19 hours ago 如果人類不會老死，就會被大自然搞死.......，我哲學家，我說的.......！年輕人想長壽，嘿嘿嘿.....再活個幾十年你的想法會改變............. Reply 施葶瑋 施葶瑋 2 days ago 口条真好👍 2 Reply Tian Mar Tian Mar 3 days ago 这种人对长寿有一定的研究，但人类自诞生至今数上百万年，特别是近两千五百年里，对长寿一直在探究，但至今还没一种公认的有效方法或药物。 Reply H C H C 2 days ago 活太久是要工作到多久 1 Reply xiao long xiao long 12 hours ago 冲绳饮食是 1:9 的蛋白质碳水比例，和美国一些低碳饮食矛盾？ Reply 別問我是誰 別問我是誰 3 days ago 10:30 重點開始 6 Reply 1 reply Chu Chu Chu Chu 4 days ago 希望可以不要那些音效，有點干擾聽覺😓😓 56 Reply 7 replies Recuerdos Recuerdos 3 days ago 最近Dr. Sinclair 推的NMN被FDA下架、不能作supplement 發售。。。 5 Reply 下一本讀什麼? · 4 replies 何俊諺 何俊諺 3 days ago 懶人包在這： 又冷又餓，吃不飽 19 Reply 2 replies 阿億 阿億 10 days ago 有點可惜，後半部你講的那個想聽看看 2 Reply cmq711 cmq711 2 days ago 環境毒素太多才會生病，還沒老化就被毒害，水中加氟、天空撒毒、空氣污染⋯⋯ 疫苗開打後多少人猝死⋯⋯ 8 Reply 3 replies 真真pokemon 真真pokemon 20 minutes ago 低蛋白飲食== 這是另一個伯格醫師嗎 Reply 謝雨軒 謝雨軒 9 days ago 我能想到最浪漫的事，就是和你一起慢慢變老 3 Reply 下一本讀什麼? · 3 replies siewken1971 siewken1971 2 days ago 进快说重点会更棒 Reply 1 reply h j h j 7 hours ago 都不老的话，地球就装不下了 Reply Jacqueline Lam Jacqueline Lam 1 day ago 這個作者本身医美, 所以說的可能有理, 但他不止会变老, 还会变丑. 1 Reply T Victor T Victor 3 days ago 饭少吃就对了，除非你要很多力气工作 5 Reply Zou Yishu Zou Yishu 8 hours ago 确定是低蛋白饮食，而不是低碳水饮食吗？ Reply iping ku iping ku 1 day ago 原來瓦基長這樣 Reply AU Alicia AU Alicia 2 days ago 灵魂永恒不死，人类的躯壳就像衣服，坏了就换一件而已。 1 Reply 1 reply serena chen serena chen 8 hours ago 很想實施168斷食計畫。請您賜教，年長者可否實行 ？ 🙏🙏 Reply 2 replies fai Wong fai Wong 2 days ago good Reply 柯美蘭。新竹縣。 柯美蘭。新竹縣。 1 day ago you are good Reply Chan Yuk Bun Chan Yuk Bun 3 days ago 應是‘’高蛋白飲食‘’ 2 Reply 1 reply Lexi Lexi 1 day ago 很少的人举手愿意活到80岁？一听就知道不是中国人😆 Reply Tim Wu Tim Wu 3 days ago 這集不要用聽的, 要來看 youtube 版 Reply 文在寅fans 文在寅fans 2 days ago 挨饿可以长寿，非洲人怎么寿命那么短 3 Reply 6 replies willy queen willy queen 1 day ago I take NMN 🎉😂😊 2 Reply 1 reply 藍Angel 藍Angel 1 day ago 請問 這本書的英文 謝謝 Reply 1 reply chai wong chai wong 2 days ago Pl look at the photo of the writer, you will notice he is not young. just the look the the same age of person. 1 Reply 2 replies Nicole2116 Nicole2116 2 days ago 有錢決定 Reply andy kwong andy kwong 1 day ago 乙酰左旋肉鹼？ 1 Reply Andrew Wang Andrew Wang 1 day ago 高雄有書友嗎？🎉 Reply 李旻毅 李旻毅 2 days ago 別啰嗦，直接講關鍵 1 Reply LIANG ZHENG LIANG ZHENG 1 day ago 高剂量营养，一天两餐 Reply Andrew Yao Andrew Yao 1 day ago 并不赞同，高蛋白维系细胞再生。低脂肪才减少自由基的产生 Reply ady kuk ady kuk 2 days ago 講得太慢也講不到重點 4 Reply FUXING WU FUXING WU 2 days ago 听了一半，全是废话，走人，替书卖广告也要给一点点人家东西听吧？ 6 Reply ann shirley ann shirley 1 day ago 藥物不講聽起來講一半。 Reply 張重生 張重生 2 days ago 又是一種無神論的説法，沒有生命的世界如何冒出來第一個細胞，對我來説根本就是錯誤，我相信有神，而且我也經歷過神，聽過祂用肉耳可聽見的聲音對我説話，對這些無神論的看法實在無法苟同。 2 Reply 6 replies wluobmai wluobmai 2 days ago 可不可以放進去一下下就好 Reply 1 reply DoraQQ DoraQQ 6 hours ago 低蛋白饮食？ Reply 失敗先生 失敗先生 1 day ago 比喻闢一大堆!??重點沒講清楚!!這樣任痕人都可隨便講!! 1 Reply 1 reply 傅青青 傅青青 1 day ago 女性也可以洗冷水澡吗 Reply 1 reply L L 1 day ago 80歲變40歲太唬爛了 1 Reply 1 reply KMS chN KMS chN 3 days ago 扯 2 Reply Peter K Peter K 1 day ago 廢話太多 Reply 釋信念 釋信念 3 days ago 我覺得你連人為什麼會長大的來源都不懂了‼️你怎麼會知道長大之後的繼續老化⁉️你講的這些其實跟老化也沒有關係❌你自己是自說自話瞎掰杜撰自嗨蹭熱度而已👎👎👎南無阿彌陀佛 2 Reply GTAdemos GTAdemos 1 day ago 科学家证实玩GTA V 可以返老还童 Reply May Xie May Xie 1 day ago 那意思是不吃食气就可以长生不老 1 Reply