Dr. Sinclair’s New Theory of Aging

Dr. Sinclair’s New Theory of Aging, Explained. Physionic 44.8K subscribers Subscribe 3.3K Share 106K views 3 months ago #drsinclair #agingresearch #healthscience JOIN MY PHYSIONIC SOCIAL NETWORK Join my Community [It’s Free!]: https://bit.ly/PhysionicCommunity Join the Physionic Insiders [Premium]: https://bit.ly/PhysionicInsiders … 307 Comments rongmaw lin Add a comment... Talia Talia 3 months ago (edited) This is a fantastic study and thanks for your breakdown analysis. I totally agree - and this now explains past studies that indicated that only 5–10% of all cancer cases can be attributed to genetic defects, whereas the remaining 90–95% have their roots in environment and lifestyle eg smoking, diet, alcohol, UV, pollutants, infections, stress, obesity, physical inactivity. Looking fwd to more on human studies too and your analysis. I will share this with my friend who is a genomics principal scientist. 77 Physionic Reply 5 replies paninopanini paninopanini 2 months ago These subjects are soo hard to explain, even to stem field students. I admire how you wanted to share this information in a more "people in general friendly" manner. Amazing how many aspects of aging is in our hands. I wonder how technology, if any, have a impact in our epigenome, the constant use of our phones and social media I think can make a impact in some way. what a great video 11 Physionic Reply Physionic · 2 replies wilmer walton wilmer walton 3 months ago Your presentation was outstanding. Just as my head began to hurt, you injected a bit of comic relief, then got right back into it. I appreciated the conclusion where you informed us that we should keep doing what we already know we should be doing to maintain our health. As is your practice you left me wanting more, much more. 32 Physionic Reply Physionic · 1 reply ScienceGuy ScienceGuy 2 months ago I'm glad to see you give credit to how hard molecular biology is. When I was in undergrad for biology, it was the most challenging course. 5 Physionic Reply sabin cioflec sabin cioflec 3 months ago Petition for a video on demon possession and longevity in mice. 136 Physionic Reply Physionic · 6 replies Ivanna Zhilinskaya Ivanna Zhilinskaya 3 months ago This was fantastically presented. Thank you for the information presented in a clear way. 10 Physionic Reply Physionic · 1 reply Mark St. Pierre Mark St. Pierre 1 month ago Concise as always, highly informative, captivating delivery and graphics. Great video 1 Physionic Reply Physionic · 1 reply Andrew W. / NH Andrew W. / NH 3 months ago Great presentation as always nicolas. It makes sense now that the "epi-" in front of genetics meaning on top - may actually refer to these "tags" you refer to. I am always ambivalent on topics involving NAD precursors supplements. While my biochemistry is admittedly pedestrian, there appears to be perplexed findings on their use on present literatures (particularly B3/NMN/NR and or even Metformin). Perhaps food for thoughts in the future? many thanks. live-it-forward, AW. 6 Physionic Reply Physionic · 1 reply Draziell Draziell 2 months ago These new videos that you breakdown the science are the best!! Please keep doing it!! 10 Physionic Reply Physionic · 1 reply Ray Fleming Ray Fleming 2 months ago How big of a roll does epigenetic tagging play with cancer versus genetic mutation. I worked as a health physicist and our story was the cancer being caused by generic mutations. But the fact that many people get the same types of cancers means it could not be due to strictly random mutations. Epigenetic differences could be a better explanation for how cancer types are so reproducable. 3 Reply Daniel Gutierrez Daniel Gutierrez 2 months ago Woooow man what a summary. I am just discovering your channel, but this review saves me a lot of time researching for my health and defining my lifestyle. 6 Physionic Reply Physionic · 1 reply photo200 photo200 2 months ago (edited) Great video, thanks. So the primary takeaway is that David Sinclair has demonstrated that epigenetic damage is more likely to be causing gradual aging than gene damage. The secondary takeaway is that Yamanaka factors can potentially reverse some of this epigenetic damage, but are too dangerous to use, presumably because if you overshoot, you end up converting everything to stem cells..?.. So, a few questions: 1. How were the Yamanaka factors controlled in the experiment, so as to unwind the epigenetic damage without damaging the mice? 2. How will this affect the direction of research? Will it focus on how to safely use Yamanaka factors, perhaps by only using some of them? Or are there other methods that show promise? 6 Reply 2 replies Brian Brian 3 months ago As a 23 year Firefighter/Paramedic, with all the toxins I’m constantly exposed to, along with the lack of consistent sleep, this tells me I’m screwed. Great info to know, though. Thanks for putting this kind of cutting edge material out. It’s very informative and much needed. 7 Physionic Reply Physionic · 12 replies cassandra stewart cassandra stewart 3 months ago Impressive analysis of the study, and so easy on the eyes, what a blessing 5 Physionic Reply Ro Blake Ro Blake 3 months ago The Epigenetic cause of aging has been shown in multiple ways. Working with fish, this evidence has become more specific. Even perfect RNA cannot make protein/peptides/hormones without having all necessary amino acids. The current evidence points to a lack of amino acids due to changes in the microbiome. It looks like their may be a universal overgrowth of parasitic bacteria over time. Humans can have trillions more of specific gut bacteria as they grow older. After all, old people appear to be starving... 7 Reply 2 replies KoiRun KoiRun 3 months ago Finally a very clear explanation of what an epigenome is for me! 8 Physionic Reply Mark van der Rijt Mark van der Rijt 3 months ago Thanks for the excellent breakdown. It was very interesting, indeed. I wonder what will happen when ageing becomes reversible. Imagine what would happen to the world's population. Or will the magic only be available for the happy few? Food for thought surely! Keep up the good work! 5 Physionic Reply 3 replies practicaltheory practicaltheory 3 months ago Would love to hear more on point 2. I mean it seems obvious to me the basic nut has been cracked and it also seems silly a 98 year old can't just roll the dice if he chooses to do so, but that's what regulatory capture will get for you. Gotta love corruption! 3 Reply Bob Le Clair Bob Le Clair 3 months ago Epigenetics is still a new word, a new idea for a lot of us, I just heard of the word about a year ago ,it fits in with many of our beliefs ,whether science or religion, a healthy lifestyle and healthy beliefs and memory leads to a healthy future, the memory part is in your young stem cells, that your parents forgot to freeze ( cryogenics) when you were young born, if you want to stay young, think young, how do you think placebos work, a positive mind is a young mind, Epigenetics, your genes are carryovers from your grandparents ,ancestral and environmental, The environmental part and that of the mind included, brings us closer to moments of notice to change in epigenetics, What is the epigenetics of a virus in terms of time compared to us humans, viruses are us, evolution, nature and memory, and then there’s biology ,virology and gene editing, we can actually tweak epigenetics in our favor, but the virus is faster, mutation, that’s epigenetics in a heart beat, you can’t beat nature, you can work with it, it’s in the genes, memory, fractal memory, does the spike carry the memory of the whole virus, mRNA to the host cell? Your playing epigenetics when you take the vaccine, pay attention to the telomeres, epigenetics 6 Reply 2 replies MetricZero MetricZero 2 months ago What I would love to see from you is a stack of 'anti-aging' supplements and some research on why each are chosen. 3 Physionic Reply Physionic · 3 replies Little Voice Little Voice 3 months ago Would you consider a video on a common age associated disease such as osteoarthritis? I'd be very interested to know effect diets (such as anti-inflammatory, sugar-free) Supplements (collagen, UC-ii, boswellia, glucosamine, vit d, turmeric, etc) Red light therapy There's a lot of information online. But I wonder how much is back by science. I'm desperate to help my mother who is struggling with hip pain from osteoarthritis 6 Physionic Reply Physionic · 4 replies Physionic Physionic 3 months ago (edited) Put a lot of work into this one - hope it’s clear and informative. If you have related questions, feel free to ask. Also, I know nothing about the NMN situation and Dr. Sinclair. This is merely an evaluation of his largest scientific work. 21 Reply 1 reply Mihaella A. Mihaella A. 2 months ago Love how you are joking, to make sure our attention span of a goldfish is on point! Thanks for this presentation, very well done! 2 Physionic Reply Physionic · 2 replies Lois Englund Lois Englund 2 months ago Wow fascinating! Thanks for the breakdown. Love your videos 1 Reply Peter Ruby Peter Ruby 3 months ago For me, the implication is that the evil powerful people of this world will be here far longer than we can bear. Another thing I noticed - what about the anti-inflammatory drugs role in aging? You didn't list them in your final three points, but they logically slow down the natural, yet unnecessary DNA damage. 2 Physionic Reply Physionic · 2 replies Lars Nyström Lars Nyström 3 months ago Your exposition of Sinclairs ideas and approach is very clear. I like to see more from you with this quality. The thing I wondered about is how equal the epigenetic changes of aging and the experiment were. And how equal the result of "repairing" those was to the none-aged ones was. What's unclear to me is if the epigenetic clock is a systematic change. Or if it's just a gross chaotic change in one direction. So, a video about that would be appreciated, if this is someting the researchers even know. I suspect they don't really know, or they would have been more clear about it. I noticed that you said nothing about that the mice being treated with anti-aging looked younger. And if they lived longer than damaged mice which didn't receive treatment. (Of course there would be some of those?) Until I see some mice actually getting younger, I don't really belive that Sinclair has proved his thesis. Making mice older isn't really the problem! 3 Reply Hermes Hermes 3 months ago Fvcking amazing talk! I loved the fact that it didnt end with eating 10kgs of broccoli, but it imparted facts that help me realise how intertwined by behaviour and my health are.. Thanks Doctor 2 Physionic Reply Physionic · 1 reply Paul Marganski Paul Marganski 2 months ago I've been taking NMN for a while now. Do you have specific thoughts on this supplement? Reply Kyu-Hun Lee Kyu-Hun Lee 2 months ago This is the first video I've seen from you. Great stuff! Also, I begrudgingly acknowledge your "cell-ves" joke 1 Physionic Reply Physionic · 1 reply The Vigilant Stewards The Vigilant Stewards 2 months ago (edited) Excellent video, sub'd. Great presentation and explanation Physionic Reply Physionic · 1 reply Jonathon Freelove Jonathon Freelove 3 months ago Brilliant break down of the study mate fascinating stuff Physionic Reply Physionic · 1 reply combiner008 combiner008 3 months ago Thank you, Nicolas, one of your best reviews! 4 Physionic Reply Physionic · 1 reply SilverFan SilverFan 3 months ago Thanks for covering this topic and David. 1 Physionic Reply Physionic · 1 reply Paulo Sousa Paulo Sousa 3 months ago Fantastic summary. Thanks! 1 Physionic Reply Physionic · 1 reply MaxiCat Hnry MaxiCat Hnry 3 months ago Great study, but honestly I would rather age than mess with my 😢dna, I swear by saunas and fasting for maintain a youthful appearance 😢 would you do a natural follow up on aging looking at what I’ve mentioned plus other scientific backed research 🔬 4 Physionic Reply Re E Re E 2 months ago Linking the study in the bio would be great! 1 Reply Valar Valar 3 months ago This 44-year-old man with a bad back and knees is cautiously optimistic. IV-therapy NAD+ has really helped me though. 1 Physionic Reply Physionic · 1 reply Minh Bao Tran Minh Bao Tran 3 months ago This has already been explained in Dr. Sinclair's book 14 years ago. 1 Physionic Reply Physionic · 1 reply Praveen Sriram Praveen Sriram 3 months ago I just subscribed to your channel after watching this video. I will also try fasting. Thank you so much 😊 Physionic Reply Physionic · 1 reply Dick Baan Dick Baan 2 months ago A huge part of aging is bluntly said, laziness, lack of exercise doin less and less. the couch and watching tv are silent killers 1 Physionic Reply Lars Nyström Lars Nyström 6 days ago The idea that epigenetic change has something to do with aging is of course immediately suggested by the existence of all those epigenetic clocks. Reply Tanner Christianson Tanner Christianson 2 months ago sinclair has me researching constantly in my spare time about longevity. Theres not a TON of things you can do, but ive come to the conclusion that carnivore diet, and exercise is the best thing for now 4 Reply 3 replies Thinking Biblically Thinking Biblically 2 months ago "The wages of sin is death." That is the cause of aging. 2 Reply Robert Rowan Robert Rowan 3 months ago Firstly, Robert Van Winkle would patently beg to differ on the question of coolness, as his alter-ego has much invested in it. That jest aside, do we know why the mice went blind? And if so, was there retinal regeneration. Or were there more simple corneal/lens issues? Either way, not a bid vid overall, well done. Physionic Reply Physionic · 1 reply Venice J Washington Venice J Washington 3 months ago Thank you for the summary! Physionic Reply Physionic · 1 reply buybuydandavis buybuydandavis 3 months ago I like the demon possession theory of aging. Implies that all we need to live forever is an exorcist. 3 Physionic Reply TheChocolat Blanc TheChocolat Blanc 2 months ago Thanks I was looking for this kind of video instead of those shorts spitting the title of the article at you and leaving you mostly confused haha. Really great to have more context. Reply L L 2 months ago What happens if we had many CT scans in our twenties? Does it mean for sure our DNA is damaged. 1 Reply 1 reply Alex Park Alex Park 3 months ago I think I’ve finally found someone with similar humor codes 😂 Physionic Reply Physionic · 1 reply Jad Jad 4 weeks ago Did i just hear Tamoxifen right? Dunno if there's another drug called Tamoxifen, but the one i know, is an estrogen inhibitor. And if that's the case, this would make youth pretty much available for everyone, since Tamoxifen is a widely spread and used drug in the industry. Can someone clear things up for me on this one, please? Reply elliott debell elliott debell 3 days ago Has Sinclair not been shamed out of science yet, as a low rate salesmen? He sold his research for a huge sum to GSK which then couldn’t be replicated by any of the other researchers. which tells me he had bias and ego leading his research. He also lied about other researchers not consulting him before they started which was not true. I take everything from that man’s mouth with a pinch of salt! Love your videos though 😊 Reply CoachDoug714 CoachDoug714 2 months ago Specific actionable takeaways or suggestions would be helpful. Reply x x x x 1 month ago 400+ videos and I found you today ? Amazed with the horrible YouTube suggestions/algorithm despite searching for health based videos all the time. Physionic Reply Physionic · 2 replies Bdjshwbwhdhh Bdjshwbwhdhh 2 months ago (edited) Dr Sinclair may have a financial interest in this view being validated because he has a business interest in longevity supplementation. Like all scientific research this should be taken with a pinch of salt until the results have been reproduced by other independent researchers. 2 Reply 1 reply matkaGrogan matkaGrogan 3 months ago Anyone knows how these Y T F (Yamanaka transcription factors) work? I mean what do they do, mechanistically? If they remove wrong epigenetic tags and (I assume) add original/healthy/correct ones to a) curb incorrect gene expression b) re-iniciate a robust/right/base gene expression - then- how do "they" (these 3 proteins) know how to do it? I mean how do "they" know which tags are supposed to be corrected? "they" must reach for some kind of a base "template" where that information is being stored... 1 Physionic Reply Physionic · 2 replies matkaGrogan matkaGrogan 3 months ago Also, what about the phenotype of that ICE+OSK mouse(mice)? did they get rid of that grey hair in the slightest? became more sturdy and frisky after applying Y F? 3 Reply Mag Mag 2 weeks ago I have a question to you. Do you take NMN, TMG, Reveratrol or something else? Reply Mango Chutney Mango Chutney 11 days ago Is this new data discovered since the publication of Sinclair's book Lifespan? Reply Matthew Flamini Matthew Flamini 2 months ago Not sure why the downregularion of yh2ax means the damage was fixed. Explain maybe, how long is this expressed after DNA damage? Maybe it's only after acute damage but then is downregulated over time. Reply Mohammad Alaliirhabiubidu Mohammad Alaliirhabiubidu 4 days ago If this dude reaches the age of 130 without looking like a nutsack I'll be a believer. Reply Lars Nyström Lars Nyström 6 days ago I'm wondering if liposomal distribution of the Yamanaka factors has been tried. Reply Grug Notice Grug Notice 4 weeks ago Why would Yamanaka factors not be made available in a CLINICAL setting? I understand that ODing on them would turn you into something out of a John Carpenter movie, but surely we could use them with proper medical supervision. Reply AHF AHF 3 months ago Ran into Dr Sinclair while in line for Dinosaur at Animal Kingdom on NYE. 2 Physionic Reply 1 reply Zack 120 Zack 120 3 months ago Since epigenome is just like the executive branch of the US government carrying out the daily jobs, it is not surprise for it to play a role in aging. Reply Sota Sota 2 months ago What anti aging supplements are ineffective? Reply Nick Junes Nick Junes 2 months ago I'd like to see more information on why we can't use the Yamanake factors ourselves? Physionic Reply Physionic · 1 reply Lars Nyström Lars Nyström 3 months ago If Sinclair belives that he can make mice younger. Why does he have to damage them first? Why not just make naturally old mice younger? And if he damage some mice and repair them. Does they live longer than damaged but not repaired mice? 4 Reply 2 replies Calvin Jackson Calvin Jackson 2 months ago But the bottom line is: can scientists slow or stop the aging process or reverse it. Reply Primal Instinct Primal Instinct 2 months ago Wonder if this implies that intentionally putting yourself into supposedly repairing "keto" state is a bad idea Reply Jonas G Jonas G 2 months ago As a human (I think) I liked this video. Physionic Reply Eyes of Ibad Eyes of Ibad 2 months ago Are we closer to longevity escape velocity? Reply Little Voice Little Voice 3 months ago How's your healthy diet progressing? In 2022, you shared some plans. Will there be a 2023 update? Physionic Reply Physionic · 1 reply Hououin Kyouma Hououin Kyouma 2 months ago Ride the spiral till the end, we may just go where no one's been 1 Reply vsaluki R vsaluki R 3 months ago (edited) Frankly, I don't trust Sinclair. And I'm betting that his answer is going to be some product for which he has the patent. 7 Physionic Reply Physionic · 5 replies UHFStation1 UHFStation1 1 month ago Good summary of similar videos. Reply applyingChatGPT applyingChatGPT 2 months ago The content was dense but you speak clearly, talk slow, and have a very calm demeanor so it was easy to digest. Awesome video! Physionic Reply Physionic · 1 reply Mitesh Patel Mitesh Patel 3 months ago I wonder how Sinclair's papers get past peer review! He's knowledgeable but he just cooks up plausible stories which some may consider scam. 3 Physionic Reply Physionic · 9 replies computerhelpcc computerhelpcc 3 months ago awesome review 1 Physionic Reply Physionic · 1 reply Book of Life Book of Life 2 months ago Aging seems to be a series of mistakes happening within the body, overload of information, energy and cleansing required to sort and heal. Fasting, reduction of toxicity, reduction of stress, while obtaining energy from sincere sources, for instance the source of energy life maintains being able to produce, do not kill the plant, animal, or being, thus a possible reason the big ass goat/sheep evolved to that point, to show people its possible to obtain life force from the milk, the fat, the moss, the fruit, the herbs, seeds, light, air, water, vibration while allowing life to be. Roses have a beneficial conductive ability however that may be obtained while allowing the rose to live, thus the possible reason of roses with thorns and without thorns, its the electrical capability, the rose petals, the humidity above the rose, the scent, the air. Will man evolve to become a complete breatharian and or capable of harnessing electricity to support life without harming or interfering with life? Are the 120+ minerals we need primarily to charge and align our positive and negative charges to balance each cell and support life force to activate and maintain our innerchi? Reply Michael Sebastian Michael Sebastian 2 months ago I almost didn't get the joke "cells" becoming your "youngercells/younger self" at first lol, great joke btw Physionic Reply Physionic · 1 reply barkmaker barkmaker 1 day ago Sinclair lost his credibility with the resveratrol debacle. Reply Matej Ravas Matej Ravas 2 months ago i'd say the biggest problem in science of ageing is that people seem to be looking for that one single key cause or holy "knob" to turn it off or even reverse it and seem to be overlooking the possibility of it being managed by a larger file or system of many factors counted in at once.. a system that is only as strong as its weakest part.. something that is very sensitive to all possible aspects of lifestyle as a whole.. maybe everyone who ever thought he found that knob was right but he didn't feel like it because they've all expected their knob to be the master one and they were purely on a quest to find that one, not allowing themselves to be satisfied with anything less while nothing more superior than what they found might not even exist, only more and more of those they already found a lot of.. Physionic Reply Physionic · 1 reply chuck duck chuck duck 2 months ago that was good , but we need an up date, on his book, I was hoping for more info. so far there has not been enough info of the influence of excerice and the interaction of the eppgentic system, and sirutins ,revitalization, ie muscle development influence on the systems, and protein, the mice ran there ass off ....and so do I....(bike ride)....and whats is now the roll of Revertrol Reply zibtihaj zibtihaj 3 months ago what do Sinclair's critics say about all this.... ? Reply Chris Winter Chris Winter 2 months ago Did I hear the name of that drug right? It's Tamoxifen? Isn't that an anti-cancer drug? Reply Gonzalo De La Maza Mendizabal Gonzalo De La Maza Mendizabal 3 months ago Interesting, I dont think there is a lot of strong evidence towards the accumulation of mutations contributing significantly to aging. Physionic Reply Physionic · 1 reply jj jj jj jj 2 months ago so dna damage could be the reason why we age ? Reply Ramon Oliveira Ramon Oliveira 2 months ago In the future, aging will be a thing of the past. Reply Vincent171090 Vincent171090 3 months ago Loved the humor :D Physionic Reply Physionic · 2 replies Dadson worldwide Dadson worldwide 2 months ago (edited) I'm not sure when abomination occurs its a grey area. A fine line! Reply Ken Bell Ken Bell 2 months ago So my take away is eat well get plenty of exercise and sleep and avoid toxins and radiation Physionic Reply Perry Stevens Perry Stevens 2 months ago Is this regarding cell DNA or mitochondrial DNA? Physionic Reply Physionic · 1 reply Παναγιωτης Αγγελ Παναγιωτης Αγγελ 2 months ago David Sinclair state that we won't reverse our biology age but reverse some deceases that are connected with the age. Reply petar mitic petar mitic 2 months ago Conclusion was the only thing I managed to follow n I did not hear anything new, eat healthy, exercise and don‘t smoke 😂 Reply Jason CHU Jason CHU 3 months ago Great ! Physionic Reply Bogse's soultrain Bogse's soultrain 6 days ago Cell... ves.. I got it...... and if they would re-make Happy Days they should give you a role. Physionic Reply Daniel Gutierrez Daniel Gutierrez 2 months ago CHF 1.00 Thanks! 1 Physionic Reply dbzwarrior4321 dbzwarrior4321 2 months ago Sooo could this bring back our baby faces? Reply LucYfYre Arch of TwiLight LucYfYre Arch of TwiLight 3 months ago Fascinating. Physionic Reply [biosecure] [biosecure] 2 months ago Don't listen to Sinclair, listen to Prof. Khavinson. 1 Reply Celestial Moon Celestial Moon 3 months ago Fasting is still the best and most effective Natural anti aging tool .. 1 Reply 1 reply Juliat Shamoun Juliat Shamoun 3 months ago (edited) 😴 Have so many questions about Dr. Sanclair product about anti-aging The NAD and NMN ... Natural Factors supplement company in Canada has the 1st product approved with NPN # (natural products registering number) approved by Canadian government The product are very very expensive??? Who will buy it like $ 225 per product 🙄 Reply 3 replies Robin Hood Robin Hood 2 months ago No 'theories' necessary when 'ageing accelerators' are being used! Reply Jean-Pierre Dalles Jean-Pierre Dalles 3 months ago is there a traduction somewhere ? Reply sudd sudd 3 months ago in the end, some want to sell you something. that is never about health. Reply Robert Gipson Robert Gipson 3 months ago Exceptionally clear.l 1 Physionic Reply Physionic · 1 reply Guts 485 Guts 485 2 months ago we will live for ever Reply Kyle Kyle 3 months ago (edited) So it's not telomere shortening that ages you anymore? 1 Reply 1 reply Qey Shinkurt Qey Shinkurt 2 months ago Hahha so this actually works? Reply Simon Long Simon Long 2 months ago Is this the NMN stuff or newer than 3 years ago? Reply Christopher Ellis Christopher Ellis 3 months ago Stopped listening to him when he went over to the Dark Side and stopped eating real food. Physionic Reply Steven Lucks Steven Lucks 2 months ago Did NMN do the same thing? Reply Doug G Doug G 2 months ago Everything grows old and dies. It’s supposed to happen Reply peous paul peous paul 3 weeks ago Lack of stable microbiome is major cause of diseases and ageing.. Reply Subtronik Subtronik 2 months ago Why the obsession with takeaways? What happened to conclusions? 1 Reply Steven Green Steven Green 2 months ago Brother has a Gordon Freeman vibe going on, need the gotee though. Physionic Reply Physionic · 1 reply Marcus Diaz Marcus Diaz 2 months ago Look I'm not the sharpest tool in the shed but any progress will be for the super-rich. However,us grunts should be worrying about one of those super mice escaping n causing some shit 😒 Reply Nick Scoli Nick Scoli 2 months ago DNA methylation and epigenetic aging is not a new theory. Physionic Reply Physionic · 2 replies Miranda Pillsbury Miranda Pillsbury 3 weeks ago its never happening yall and if it does we will all be gone. Reply Brian WNC Brian WNC 3 months ago This is not new. Dr Sinclair proposed this theory a decade ago Reply Physionic · 1 reply iv3nomousi iv3nomousi 2 months ago So you would advise that I not eat 2lbs of Uranium each day? Physionic Reply Physionic · 2 replies Steven Weigand Steven Weigand 2 months ago I think there's a giant spider on your wall behind you! Look out! Reply 1 reply Edoardo Edoardo 1 month ago aging process doesn't exist. aging is a belief. Nothing ages. No one ages.body is new every year. We are energy and energy is eternal. Phisical immortality is our true nature. Reply