Electron transport chain

Electron transport chain Harvard Online 198K subscribers Subscribe Like Share Download Clip Save 2,776,353 views Oct 9, 2017 From our free online course, “Cell Biology: Mitochondria”: https://www.edx.org/course/cell-biolo... Harvard Professor Rob Lue explains how mitochondrial diseases are inherited and discusses the threshold effect and its implications for mitochondrial disease inheritance. — Subscribe to our channel: / @harvardonline — Sign up for emails about new courses: https://harvardx.link/email — HarvardX courses on edX: https://www.edx.org/school/harvardx — Harvard University's online courses: https://online-learning.harvard.edu/ HarvardX empowers the faculty of Harvard University to create high-quality online courses in subjects ranging from computer science to history, education, and religion. Key moments View all Transcript Follow along using the transcript. Show transcript Harvard Online 198K subscribers Videos About Instagram Facebook LinkedIn Twitter 2,138 Comments rongmaw lin Add a comment... Pinned by Harvard Online @HarvardOnline 5 years ago (edited) Learn more in our free online course, “Cell Biology: Mitochondria”: https://harvardx.link/pwnt 315 Reply 15 replies @LavenderTheArj 4 years ago I remember when I was studying biochemistry II in my bachelor's degree, desperately looking for a video on this on the night before the final exam, didn't find one and had to memorize it the old fashioned way, all I'm saying is that what you're doing is extremely valuable for a lot of students, best of luck. 2.8K Reply 25 replies @Roger-go6jc 1 year ago This is just awesome. I'm 69 now and still doing paediatric nursing, but started my career in Pathology. I remember pawing through my Biochemistry text to sit exams and trying to memorise the Krebs Cycle, which is all part of this. But the process I did on a page that showed chemical energy utilised for cellular respiration has just blown right off the page. This visual takes me into a Mitochondria and starts to put the cycle into a visual sense. What a wonderful progression in knowledge we have. Now lets not forget who we are and what a beautiful planet we have. 25 Reply 1 reply @lilyilyily323 3 years ago RIP prof lue, this video is just one of many thousands of wonderfully helpful, selfless things he contributed to the world during his too-short lifetime. 73 Reply @vedantbhardwaj7582 9 months ago I'm a medical student at King's College London, and honestly this has helped me sooo much with actually being able to visualise how Oxidative Respiration actually occurs! Thanks!!!!!!!! 8 Reply 3 replies @hosoiarchives4858 2 years ago (edited) 0:29 inner mitochondrial membrane 0:47 key role is to separate protons, inner from outer protons 1:08 ATP synthase, makes ATP. Uses proton flow to work 2:24 Complexes 1, 3 and 4 pump protons out 2:49 complexes get energy from electrons 3:18 complex 1 uses NADH and reduces it 154 Reply 3 replies 4 years ago Imagine a whole biochemistry book animated like this... I wish I'd be alive till then :'( 2.7K Reply 31 replies @nickmagrick7702 4 years ago the visual explanation really helps a lot. 285 Reply @noelsrx376 4 years ago This is physics, chemistry and biology combined in one! And I love it!! 636 Reply 36 replies @TommyTumma 8 months ago Professor Lue’s microbiology course at Harvard was really easy to understand. The hallmark of a great teacher. I recommend taking his full online class for free! 3 Reply 1 reply @Lisargarza 2 years ago Learned all this stuff in grad school 40 years ago, but it was more like a concept, a chemical formula written on a page. To see it spring to life as an animated video is astounding. Thanks for posting. 21 Reply 1 reply @raplopez4258 3 years ago (edited) What makes this video stand out is not just the breaks, but the respect for the student, BY GIVING US 5-30 SECOND BREAKS TO JUST RELAX THE BRAIN!!!! (*Cough to all you other science videos/teachers out there cough cough*) 7 Reply @hasen_judi 4 years ago "and this is why we have to breath oxygen" was a mind blowing moment for me. 2.8K Reply 138 replies @lucachirico4183 2 years ago I watched this video 3 years ago for the First time, when I was studying biochemistry for the exam of the bacheloor degree. Now I've just re-watched it to review the topic at all for work, and it's gorgeous like ever. I think immagines and videos can teach better then thousand of a book's pages. Colours and animations are for me the best way to rember and put every feature in our brain. 5 Reply @AmruMagdy 11 months ago Such a great, clear explanation! Videos like this remind me why I love biology so much. Life is amazing. 2 Reply @fabiobarreiro 4 months ago It's almost unbelievable how complex and precise life is. A lot of hard work to keep us alive. 1 Reply @tag180rotax 2 years ago Mitochondria is the powerhouse of the cell 7 Reply @killianoshaughnessy1174 4 years ago I am amazed at the complexity of being alive. 374 Reply 41 replies @aryansaeedi7618 4 years ago My god what a beautiful video. Very clear and well explained. I’m in love with this channel. 550 Reply 15 replies @audreya7543 4 months ago This is easily the most clear-cut and visually useful aid I could find online to look at the ETC complexes 1-4. I can't thank you enough for this resource! Reply @aylinm5439 2 years ago I love how he stops occasionally, so the knowledge sinks in. Thank you so much, helped alot. Reply @jayski9410 4 years ago I wish we could have had visualizations like this back when I was a pre-med student in the 1970's. All we had were acronyms, arrows, and line drawings. The best analogy I can come up with is a wrist watch - in my day we could look at the watch face but just read about what made the hands go around; this animation is like opening up the back of the watch and finally seeing all the gears and springs in action. 11 Reply 1 reply @peterschmidt1453 3 years ago We can thank Drew Berry for pioneering the animation of this invisible world, his ability to visualise these subatomic processes has made these animations possible. 34 Reply @maryamfazal3180 2 years ago No other video could convey the concept that this video has conveyed. Best video ever, I'll never forget ETC ever again. 1 Reply @riponsutradhar2908 4 months ago One of the best animations & explanations available in the internet regarding electron transport chain. Reply @yvonnemoreno8805 3 years ago This is amazing. It puts all these concepts we're inundated with and makes it more clear. As a visual learner, I wish there were more animated videos like this! 42 Reply @Darkmatter321 4 years ago This happens a few Trillion times a second in our bodies. No big deal! 356 Reply 57 replies @Ronin777z 3 years ago The animation was incredibly helpful in understanding the material. My mind tends to wander during lessons so the visual aspect was immensely helpful. 32 Reply @andrebonneau9919 2 years ago I'm a physician with a bachelor's in biochemistry. Great images to transmit knowledge not just electrons. 1 Reply @theSilentPsycho 4 months ago Thank you for creating this video. As a software engineer, I've always been intrigued by understanding the intricacies of how things operate on a smaller scale. Your video also highlights how we often operate in our professional lives akin to machines, much like the mitochondria units showcased, and how this can sometimes obscure our awareness of the broader universe to which we belong. It serves as a reminder that we each have a unique purpose within this vast ecosystem. Reply @rachelchristiansen9218 4 years ago I was literally feeling so screwed over my biochem exam because i could NOT grasp this concept. This was so clear and easily explained and I feel way more confident going into my test, and better yet it was INTERESTING and easy to continue to watch. Thanks!! 46 Reply 4 replies @samp-w7439 3 years ago The fact that this is constantly going on in our bodies is insane. The fact that people have somehow figured out all the details and intricacies of this tiny and complicated processes is on a whole other level! 10 Reply @greggrobinson5116 3 years ago Seeing this chemistry written out as reactions is impressive enough, but seeing it animated is just astonishing! And to think that this is going on effortlessly in every one of our cells all the time is downright religious. 12 Reply @sinayasharabi8302 1 year ago I have recently been obsessed with animations of this theme, they are simply fascinating. Reply @akashhera 3 months ago Undoubtedly the best animation in this topic out there!😍 1 Reply @PheedPhil 3 years ago Great video. Haven't seen a better animation anywhere else. And very accurate too, with the exception of one small detail (which most text books also get wrong). FADH2 is not the electron donor to complex II, it is physically attached to the first protein of the complex (a flavoprotein). Succinate is the electron donor (CII is called succinate dehydrogenase) and CII oxidizes it to fumarate in the Krebs cycle, passing the electrons to it's FAD, and onward into the complex. 36 Reply 4 replies @kritikathakur5895 3 years ago We want animations like this really. They helps us to have a deep insight in the topics. Thanks 4 Reply @xinchen3547 3 years ago Respect to the masterpiece of the Creator, and the marvelous job of the makers of this video. 17 Reply 3 replies @addictionmystyle3718 7 months ago This type of videos are valuable. These non seen tiny creatures are doing their best amazingly. But why they are do their duty for us...?it's complicated. So we have lots of responsibilities. Nowadays science students are blessed and I wish they need to see it. 1 Reply @myblueparadise5807 1 year ago This is the best animation I've seen so far....I just have no words to appreciate you❤ 1 Reply @jesusmiguelalvarezfernande8761 2 years ago Just the opposite of what happens during photosynthesis in chloroplasts. What a wonderful balance! 12 Reply @edehc 3 years ago INSANE IN THE MEMBRANE! AND ALL OF THIS IS HELD TOGETHER BY DIFFERENCES IN ELECTRICAL CHARGES? JUST WOW… 25 Reply @dickmorhead6165 4 years ago I have my mother's eyes and my mother's mitochondria. 91 Reply 2 replies @michaelrobinson9952 5 months ago The line between the three big scientific disciplines becomes blurred here, wonderful. Reply @MaverickMusic-fu1yt 3 months ago You are fearfully and wonderfully MADE. God bless you everyone. You are more valuable than anything else in this world. Reply @geofractal 4 years ago (edited) This is incredibly amazing. It is also amazing that humans can figure this out -- very smart humans, that is. 110 Reply 6 replies @ectogamut 4 years ago 5:19 The shark tooth ghosts show up, get their eyeballs, and leave. 399 Reply 10 replies @MichaelBethel 3 years ago This really amplifies the words of the Psalmist when he says "I will praise You, for I am fearfully and wonderfully made; Marvelous are Your works, and that my soul knows very well." Psalm 139:14 8 Reply 2 replies @lecturestudio4640 2 years ago (edited) I wish these resources were present when I was doing my graduation studies. Would have made my efforts so much more mindful and meaningful 1 Reply @BushCampingTools 4 years ago Just the best! My 9 YO is learning all about this; why? he asked me why will we die if we don't breath oxygen, this created for me to teach him about the: ETC, Mitochondria, poisons of the ETC; proteins etc etc. Plus Organic chemistry LOL. Who says kids can not learn and understand this stuff. Why it's not taught at junior level i have no idea, especially when they are so curious at a young age. The animations really help with the understanding. Like why the proteins are shaped like they are; another great avenue to pursue with some organic chemistry etc. tie it all together kids love it. Reply @andychow5509 4 years ago Wow. Amazing how much progress and knowledge we are starting to have access to. Never saw anything like this when I was growing up. 12 Reply @rolandoe.diazolivom.d.4777 4 years ago Congratulations for this excellent video. Next up, please: The microscopic machinery of the outer mitochondrial membrane. This is the gatekeeper preventing a massive influx of H+ and other cations in the surrounding matrix from entering the inner mitochondrial matrix. 10 Reply @divinephanes 3 years ago I remember seeing this in my first year bio class, it blew my mind when I first saw it and it still does. Thank you for this! 9 Reply @abdulmajid427 1 year ago The same topic I've been taught regarding Respiration in plants, the following week & I'm taking this vid as revision purpose ❤ 1 Reply @kitony 2 months ago Students life must be great with these animated videos and AI. Reply @ngc-ho1xd 4 years ago Life is the ultimate Rube Goldberg machine, that in essence performs a task very similar to Maxwell's deamon. It's so beautiful! 16 Reply 2 replies @igoralencar4817 4 years ago This is so beautiful. I've been looking at it for five hours. 17 Reply @SoirEkim 4 years ago I may not be fully aware of what it took to put this information together. Yet, I love learning in this way and the visuals are mesmerizing. Therefore I would willingly watch several days worth of videos like this. Excellent! Thank you. 5 Reply @noisepuppet 1 year ago (edited) We need a single illustrated page explaining this with bullet points that users will understand at a glance. --IT Management Reply @ethqn996 10 months ago what a beautiful world we live in. what a joy it is to be alive. how amazing is it that we are so wonderfully complex Reply @stephenarmiger8343 2 years ago Reading Brian Greene’s book, Until the End of Time. He does an admirable job explaining this. I appreciate this attempt to help us understand the situation in three dimensions! 3 Reply @nikitasid4947 4 years ago That feeling when you read an offline paper book on Mitochondria and then Youtube recommends you this. 11 Reply 3 replies @Vivanwho 1 year ago How did mankind find this out. It's still so bizarre 5 Reply 1 reply @medni6311 1 month ago What a fantastic voice with excellent teaching methods. Stunning education approach. Thank you from the whole heart, not just from the bottom. I am leaning toward to derma specialty, and without knowing all these fantastic body processes, it is impossible to deal with skin issues. Reply @apothecurio 2 years ago The jump from atomic particles make a thing that is deemed as a system that sustains itself had always fascinated me and ,as a lowly layman, found it hard to actually find where I could find that info. This is the perfect start. Amazing. 1 Reply @oleksiyalkhazov9201 4 years ago Science is the best mystery and greatest magic in the multiverse 7 Reply @iainmacdonald8379 4 years ago I'm reading The Vital Question by Nick Lane and this video really helped me to understand respiration, particularly redox. Fantastic book, by the way. 3 Reply @IzzytMe 3 years ago So I can actually harness quantum energy in each cell of my body, simply by breathing oxygen and my teacher said I'm no good at physics. That can't be right! 14 Reply @swnerd-2320 3 weeks ago I have a biology degree and am here to refresh my memory of these important concepts. Thank you! 1 Reply 1 reply @probability_density 3 years ago Videos like these showed me the astonishing complexity present in our lives. I have never gone back to my old way of viewing the world since those formative adolescent years. Reply 1 reply @fotoflo 4 years ago 4:26 - "a small amount of energy is released each time an electron is passed between redux centers" -- in what form is the energy released and stored? 68 Reply 40 replies @kaukabbhatti1661 4 years ago To be honest, this is the best animation I have seen on this subject. 4 Reply 1 reply @denisa.6793 4 years ago oh my god, i praise the author, incredibly helpful 35 Reply 8 replies @JMYaden 6 months ago These clever animations really make this whole fascinating process come alive. Thank you! I will take your free online course! Reply @prestonburton8504 9 months ago amazing - i had to 'memorize this' to pass engineering late 1970s - there was nothing like your incredible animation and description. memorizing it? didn't mean i knew it - i do now, thanks to you! Reply @howtogaintime739 4 years ago What a beautiful little world, wish I could see it up close. 12 Reply 4 replies @redemptivememelord6283 3 years ago For once I read it as "Electron transport chan" and I thought I'd meet a molecular biology waifu 53 Reply 2 replies @mingngyt 4 years ago This was beautiful. amazing music and lesson. 10 Reply 3 replies @sanjibsarmah1582 2 years ago Most effective and easy understand elaborative video ever Reply @johnathanh9369 3 years ago I start off watching videos then I dig into the textbook so then I can imagine it. This allows me to memorize and understand it better. 2 Reply @ashypharaoh8407 1 year ago Who else is carrying out oxidative phosphorylation while watching this? 10 Reply @fzka_ 4 years ago This is such a good visual explanation. Thanks! 4 Reply @rodneywar 4 years ago Thank you for sharing this highly educational video. 5 Reply 2 replies @sangitasharma4692 1 year ago This is one of the best animation video i have ever seen with such a great and clear explanation Reply @manurenier2534 1 year ago amazing video, we biochemist students from KULeuven (Belgium) love this ! Reply @writer24x7 4 years ago 4:26 A small amount of energy is released? Energy in what form? How the complex harnesses this energy? 5 Reply 1 reply @BramMichaelson 4 years ago I think I've seen all this before when I got REALLY high. 24 Reply @rodschmidt8952 4 years ago When the gradient is insufficient and the mitochondria no longer produce ATP, the cell can become starved of energy and -- become cancerous? Are not small amounts (~5%) of ATP always produced elsewhere in the cell by fermentation? 8 Reply 7 replies @theresaditz6271 1 year ago Thank you from Düsseldorf -Germany. I study medicine and this saves me! Reply @عبدالوهابالطلى 3 months ago And some deny the intelligence and power behind all this truly admirable demonstration of power and art exhibition from nanoscales to gigascales can't be without creator 1 Reply 1 reply @ferid9k 3 years ago (edited) 1:40 thats actually just a theory.We still dont know how atp synthase works 6 Reply 1 reply @rcarmisin3465 4 years ago I got so lost watching this video, it was 20 minutes later until i realized i was staring at the wall. lol :) 5 Reply @opeoluwaabiona3898 4 years ago 0:40 : Wow, this is like an endless ball pool! 3 Reply 1 reply @michaelK.3272 2 years ago This is one of the most informative videos I have ever seen. Excellent quality. Thank you! 2 Reply @Minalkra 3 years ago I'm not a biochemist. I'm a mail clerk. And yet here I am, learning about how exactly the ATP process works and how linked it is to respiration. I mean, I KNEW it was linked to respiration at a conceptual level and all, but the specifics were never explained until now. 1 Reply @Bitmaker64 3 years ago Who else just likes to see this animations. 3 Reply @danteseluvathingal5292 5 years ago That was amazing.thanku soo much 4 Reply @Mighty_Deeds 2 years ago God's craftsmanship. A design of perfection. 6 Reply 2 replies @narek335 2 months ago This is my favorite biochem. video ever Reply @Geminish15 6 months ago I could tell by the background music right away this was gonna be legit with the visuals Reply @An0nim0u5 5 years ago Please can you guys make a video on Photosynthesis as well...??? 4 Reply 2 replies @linenkeyes6329 2 years ago Anyone else here from meow wolf? 4 Reply @KatherineShay 3 years ago Who is here from Meow Wolf?? 4 Reply @tomorourke6301 3 years ago Since I've gotten Clean and Sober, this has become my all-time favorite video...feels like a Plato's mystery school subset.... Reply @atharva7375 3 months ago Mindblowing visualization... I had doubt in ets in my class 11th respiration chapter... But now this is gonna be my favourite part of the chapter 🔥🫶🏻 Reply @ElectricityTaster 4 years ago ahh yes, the powerplant of the cell. 15 Reply 1 reply @neigeepierrot4694 4 years ago Amazing this happens everyday 4 Reply 6 replies @theconfussy924 5 months ago Neet ug aspirant👍👍 3 Reply 1 reply @alfrednewman2234 2 years ago fantastic. Love Nick Lane's contribution to Kreb's citric acid cycle, and life's origins/cancer's abbherration Reply @paulcarne2892 7 months ago And this all happened by chance given enough time! I doubt very much that anything this complicated could assemble itself, no matter how much time. This is an example of exquisite engineering of the highest order. Reply @schunack6433 4 years ago It’s actually called FoF1 ATPase not FzeroF1 ATPase; great video otherwise! 4 Reply @michaelayeni177 4 years ago Glory be to God 10 Reply 1 reply @josevictor6687 1 year ago We see in The Perfection of The Creation of The Lord God. 7 Reply @Sidguru101 1 year ago explained so beautifully yet its so vague thinking about all these processes occurring all at once Reply @trainerbrock2428 3 years ago Videos like this are the future of molecular biology education at all levels. Great video!! 1 Reply @yvonneott8758 4 years ago Primordial soup, or magic potion? 5 Reply 7 replies 4 years ago God made all of this as if we make a rag doll. 4 Reply @aryaardiodio 2 months ago God is Great 4 Reply 1 reply @themedico20 1 year ago My test the day after tomorrow loses its nightmarish vibes because of this video! Thanks a lot. Reply @cholabit1532 1 year ago Chills! Literal chills❤ Mahn, I love every second of this video ❤❤ 1 Reply @raymondndungu6447 11 months ago May the Lord receive the glory due His name! He has created us amazingly! And yet, despite sinners’ rebellion, God sent His Son Jesus Christ to live the perfect life and die a ransoming death so that those who believe in Him might not perish but have eternal life. 7 Reply @sunshine_of_csy 1 year ago This is such a dope video for ETC,I am totally visualizing what I have read in books Reply @amira6405 1 year ago I just clicked on this video. 10 seconds in and I am welcomed by a voice I recognize. The voice of a fellow Jamaican (RIP to Robert Lue). It's so surreal how just a voice can connect you to someone and now to a video I am wholly excited to watch and learn from. 1 Reply @fantaxtick9482 2 years ago The most amazing thing about this is that all this came into being all by itself. Wow 2 Reply 4 replies @Pablooov 2 years ago perfect visual of "The mitochondria is the powerhouse of the cell" Reply @Hiteshshlaki 3 years ago What an animation!!....This should win Oscar 1 Reply @m0sbah4 2 years ago this one of the best explaining videos i had ever seen Reply @coopdeville4933 5 months ago This video illustration is one of the best things I've ever seen. I can see I should have been a biologist. This is one big beautiful puzzle that I must solve, even on my own time Reply @damoneaves 2 years ago This Animation appears to scale. Love it. THANK YOU for the animation and narration it’s great. Nerd/dork manna from heaven Reply @unhombrealado 7 months ago It’s incredible what happens in trillion of our cells, and it’s even more astonishing that we’ve been able to gain this level of understanding of what goes on. Wow Reply @matyasmatta 10 months ago Unbelievable. So beautifully animated. Reply @anonim5052 2 years ago Mitochondria is a powerhouse of a cell Reply @tombenson5957 1 year ago (edited) What an amazing video. Just imagine, every mitochondria has zillions of molecular crankshafts, spinning away generating power, and you have 100 Quadrillion mitochondria more or less in your body. Reply 4 years ago Thank you so much. Greetings form a Molecular Biology Research Group (BIMAC) at Universidad del Cauca, Popayan, Colombia. 1 Reply @imnotridaaa 2 years ago This is all happening in every single mitochondria of my body giving me high voltage goosebumps! ⚡ Reply @rickastleyrule3497 1 year ago (edited) We live in a day and age where top educational institutions offer courses available to the public for free, anyone from the us to Pakistan can simply search a topic up and study away truly the advent of technology is nothing short of a miracle Reply @mrinalsahu7991 7 months ago Explained everything so beautifully Reply @helmutzollner5496 1 year ago Great Animatiin. It makes this complex subjevtbso much more tangible. Thank you. Reply @andrewflowers1755 2 years ago FASCINATING/BLOWS ME AWAY !! ⭐💪🦾💥🔥💫💫💫 Reply @m3nt4l173 2 years ago Mitochondria is indeed the powerhouse of the cell. 1 Reply @ameliabarrett8805 1 year ago I never expected to be learning this much biochemistry in my Bio 101 college class but...here I am. Thank god for this video! Reply @skitoes974 2 years ago The only video I could understand as I'm about writing my biochemistry exams thanks 🙏 Reply @itssaptarshi1826 1 year ago U just brought biology to whole another level .. hatsoff 🎉 Reply @WildlifeGuy 1 year ago I wish I had these types of videos when I was getting my Biology degree back in 2001. Reply @Coppermeshman 4 months ago (edited) Life so delicate, yet so much potential. Reply @nikolasortega3346 3 years ago God this is amazing i whish i had these kind of videos when i had to studied this for my molecular biology exam All i can say is this is pure gold 2 Reply @leifharmsen 1 year ago (edited) Imagine I've lived for 55 years with all this going on and didn't even know about it. What was I thinking; that it was magic? You'd think people would be deadly curious about how it all worked until they figured it out. Oh, that's what you're doing. Bravo! Reply @jerryo1228 1 year ago Excellent video, with very complex processes; explained clearly and easily to understand. Reply @macrofage1551 4 years ago Nature is fabulously complex and stunning at any scale. Reply @amelghwel 1 year ago Thank you so much for this video! I'm studying Biochemistry II and this is the very first time I understand completely how electron transport chain works. Thank you very much for your efforts. Reply @rthmjohn 4 years ago Hands down, best video on the ETC on YouTube. Reply @BPLeroyLotusEvora 4 years ago Absolutely fantastic educational video about the mechanisms of mitochondrial energy production! 1 Reply @yashjoshan233 2 years ago Never thought that I can understand this topic so easily like within 7 minutes... all credit goes to this animated video thnq so much Reply @1.4142 1 year ago If all courses were like this we would have world peace. Reply @thomascorbett2936 3 years ago The things that mankind is able to figure out understand is the most amazing thing to me . Reply @bharathwajramesh4712 1 year ago you ppl really deserve millions of subscribers.!!!!!!. really great Reply @sam.asdfjkl 2 years ago Hats off to the creator 👏🏻👏🏻 2 Reply @taslim3650 4 years ago Respect to who contributed to make this Amazing video 1 Reply @CodNinja33 2 years ago Really makes me miss Rob Lue 😢 Reply @rhosoojin191 4 months ago This animation is so beautiful and well made ❤ Reply @motivational..3 2 years ago A very helpful animation that cleard the my whole doubt about this concept Reply @abhinabachakraborty7207 3 years ago Dont have words to appreciate enough how beautifully this video has been made 🥰 1 Reply @jadhavaniket100 3 years ago I was searching for a perfect explanation for the ETC and couldn't find any. Came to YouTube and saw your video and was blown away. Thank you so much. It shows that it has taken immense efforts to create this amazing video. Thank you once again.. Reply @terrihenges8743 1 year ago I am not a scientist but have been learning about nutrition and it seems at the heart of all metabolic processes the optimal functioning of our mitochondria is the key to good health. Our Western processed food diet is the reason our mitochondria, and we as a society, are sick. Reply @chromebaby 2 years ago I can comprehend how evolution produced the variety of animal and plant shapes there are. I can even comprehend how eyes and flowers that mimic the shapes of insects evolved. I can also just about get my head around how cells evolved – barely though. But I can’t begin to fathom how any of this got going. What were the stages before what’s happening in our mitochondria now? How did all those protein shapes come about? And their behaviours? It’s utterly insane what’s happening here. Reply @toybajan85 1 year ago Mind blowing presentation 👍 1 Reply @viniciusbenine7063 2 years ago I've learned so much watching on this video than my whole school life. Reply @martinheymogensen 3 years ago Best illustration of the ETC I have every seen!!!!! Reply @hobobazaar8196 2 years ago Great video, I have long known that the mitochondria is the powerhouse of the cell. Now I know why! Reply @dlu0813 3 years ago The simulations for the phospholipid bilayer at 0:45 are SO cool! 😄 Reply 1 reply @pinkcripps2749 2 years ago So this is why the mitochondria is the powerhouse of the cell Reply @JohnHillEU 2 years ago Very newly interested in biochemistry and it's amazing to see the similarity in the proton concentration gradient has with the mechanisms at play in silicon transistors! 2 Reply @mjllle6603 2 years ago best video for understanding ETC 👍🏼👍🏼👍🏼👍🏼👍🏼👍🏼 1 Reply @chrisgreen1904 2 years ago Thanks Harvard. Great tool for learning the ETC. Bravo 👏 Reply @kalldr6355 2 years ago Thank you so much for this, you're saving lives out here 1 Reply @nuibui6667 2 years ago It is weird how what is taught to people in the west in biochem courses is taught to us in India in schools. Great video btw. 1 Reply @nsbd90now 2 years ago (edited) I like biology and I really like modern animations of biological processes. Absolutely amazing! I subscribed. 2 Reply @XFz2nLDWo73x95 2 years ago I am not a biochem student.. but I will always nerd out on these videos. <3 Reply @DavidStruveDesigns 2 years ago (edited) I love this video! It amazes me that inside every cell of our bodies we have what essentially is hydro-electric dams complete with turbines that enable our cells to do work - albeit using the controlled flow of protons in place of the flow of water. Yet again, nature beat us to the punch when it came to invention! Funny how we came up with the exact same solution to our power needs with NO idea we already had the same design hidden deep within ourselves. 1 Reply 1 reply @tomhorseman9832 3 years ago I knownthis is viewed as "boring lecture crap" but this stuff fascinates me so much. And I absolutely love it. I went to college for this shit but had to leave during my last semester. Reply @letsgo4834 3 years ago Beautiful. I wish I’d had this type of material from which to learn and review years ago. 1 Reply @AyeshMedic 2 years ago This was Amazing!!! The most distinct video of it's type. I was having so much trouble in ETC and here it is in such an easy way. Good Job. 2 Reply @sunitha4037 4 years ago Crystal clear visual explanation ✌ 1 Reply @Ren-v9m 2 years ago This is extremely helpful for me !!!!!!! Super grateful for the master piece that you produced ! 2 Reply @ronaldagnes2269 3 years ago De are wonderfully MADE... 1 Reply @nihalrasheed9827 4 years ago So one question, FADH2 doesn't use energy to pump protons... So where does it go? Also how is Complex 3 pumping protons? Incredible video sir! Absolutely phenomenal how clear it made this process to me . I can finally appreciate how magnificent our body is and the importance of each point we study now I know how it all works , Bravo 2 Reply 1 reply @SarimaWrites 1 year ago We're offering this course this semester Reply @bitterlemonboy 1 year ago the mitochondria is the powerhouse of the cell Reply @杨涛-r4q 1 year ago really useful for students studying Cell Biology, lots of thanks. Reply @jdogcisco1 4 years ago Hard to believe some chemicals just happen to get together to make amino acids that get together to make proteins that get together to make structures that have such intricate processes like this that are necessary for yet a larger structure to 'survive', which are yet still part of a larger organism that figures all this stuff out. Mind blowing. Reply 1 reply @yeahitsok3246 5 months ago This Helped me out in MBIOS 303 Reply @eloimumford5247 2 years ago Bright brains and lot of knowledge condensed in a short video , thanks. Reply @rickaguilar1833 1 year ago I wish they had this computer animation when I took my medical school biochemistry courses! Reply @shuvradeepkar4349 1 year ago Only one word : AMAZING!! Reply @sweetpea7270 2 years ago incredibly helpful, and great animations, THANK YOU SO MUCH 1 Reply @suhaniprajapati4799 3 years ago best video on ETS !! I finally understood it!!thank you very much!!!!! Reply @Raja-kr8ul 1 year ago Thanks for your video sir. Excellent video sir. Excellently explained. God bless you. Reply @yadavkomal 1 year ago Thank youuuuuu.... Understood it in its entirety for tye first timeeeeee😮😮😮😮😮😮🙏🏼🩷 1 Reply @makaylamoore8831 4 years ago Such a great, clear explanation! Videos like this remind me why I love biology so much. Life is amazing. 189 Reply 1 reply @SoirEkim 4 years ago I may not be fully aware of what it took to put this information together. Yet, I love learning in this way and the visuals are mesmerizing. Therefore I would willingly watch several days worth of videos like this. Excellent! Thank you. 1 Reply @Margo296 3 years ago Finally I understood what the electron transport chain is! Thank you so much <3 1 Reply @SunilKumar-zs5vh 2 years ago this was in our 11 th grade biology textbook in India and it explained whole information and some additional details that s not in the video.. i was amazed to see that this topic is in bachelor degree of biochemistry too ... great .. loved the animation 2 Reply 1 reply @james7951 6 months ago How is this so beyond helpful??? 😂 Amazing work. I understand this so much better now Reply @ashitkumardutta6582 11 months ago Addresses to all the small details! outstanding! Reply 1 reply @paolopenna2668 2 years ago Compliments! Is very complete and esaustive explanation of this argoment. Reply @climateguy2488 1 year ago Just wonderful. In awe. I wish i went into this field of work Reply @rosannaalexis 2 years ago So beautifully intricate. Thank you for this video! 1 Reply @Richard_Ashton 2 years ago If I'd only had this when I was doing my degree paper of Aerobacter Aerogenes back in the early 70s. So before computers it was so hard. 2 Reply 3 replies @lastyhopper2792 2 years ago Alright, questions time: 1. Why protein complex 1 and 2 uses different byproduct of sugar metabolism (FADH and FADH 2) 2. Why complex 2 even need to exist? From this short video it seems like the complex 1 is the superior version of complex 2 I'll come up with other questions later, after I learned more stuffs Reply @semexambcma 3 years ago Just mind blowing. thanks you all of the team. Reply @idegteke 2 years ago Yes, I thought it might work like this, but thank you for providing some extra details:) Reply @kamalim982 10 months ago Woah! The best one i have ever watched and ur prounciation is just awesome 👍 thank u sir😊 Reply @gkmurthy6529 4 years ago 🙏🙏 thank you Dale muzzey sir for such a animation 1 Reply @conebread4333 3 weeks ago (edited) I feel existential appreciation. No book ever wrote itself. Biology is the most complex arrangement of information. DNA for example is complex code. It CARRIES and transmits the information; but it is NOT the actual information. Just like language and math carry information. But information itself is immaterial. It’s interesting that the material world is governed by and predicated on the pre-existence of immaterial information……to me, accepting that life is a book that wrote itself and then became aware of its own existence is not satisfactory. The hurdles and holes of abiogenesis are insurmountable for the foreseen future with a materialistic attempt at the explanation of causality. Reply @harshitharajshekar2234 3 years ago No one Can't beet this kind of explanation 👌👌 Reply @MasterFeiFongWong 2 years ago (By AMA) To whom it may concern. The Key to making an over unity Electric generator work is mechanical advantage. In this case the mechanical advantage is achieved by getting the electric motor that is spinning to be able to spin a quantity of separate discs that are connected to devices that generate electrical current to generate more current then the electric motor needs to spin. One of the ways to achieve this without violating the laws of thermo dynamics is to exploit magnetic field effects. To do this you place the magnets on the disc that the electric motor is spinning in a way that makes it so while the disc is spinning around the magnetic fields are slamming upwards onto the edge of the other discs forcing them to spin, thereby generating electric current. In this way, the magnetic fields will be forced to do work that the electric motor wont be doing. This is how it's possible to achieve an Over Unity Electric generator & with this technology we can free ourselves from the use of gas. By AMA Reply @pawerymut9033 2 years ago Your prononounciation od word organells, with The accent on The middle syllabe is so strange and unnatural that i cant listen to this, it gives me goosebumps. Reply @AKORD24 3 months ago Thank you, you have my deepest blessings ❤❤ Reply @MrAmalthejus 3 years ago This video made me emotional Reply @hemo2458 1 year ago This is very fantastic 1 Reply @jimking6484 3 months ago Fantastic explanation! Thank you!! Reply @lorrainecamilly7354 2 years ago É um dos melhores vídeos sobre o assunto que eu vi, muito didático. Excelente! 1 Reply @joshithmurthy6209 3 years ago (edited) OMG!!! the animation is awesome !!!, I love this channel, it explained ETS in the best way. Reply @partypao 4 years ago Wow!! Now I've finally understand it!! Books can never explain a complex process as this! Reply @clairerolland7239 1 year ago It's so beautiful, I'm lacking of "adjectifs" ! You are the Michel Ange of the life views of cells. Thank you so much ! when looking through mirror, I shall see another ! I would like to be younger and join your studies ! so gracefull Reply @fangugel3812 2 years ago Very nice. It would have been great to show this to students when I was teaching biochemistry. Reply @MrAmalthejus 3 years ago It is incredible to think that such systems evolved on their own. 1 Reply 1 reply @evenhauge5579 1 year ago Didn't expect Gus Fring to help me with biochem Reply @singalongwrudy8690 1 year ago I wish I could have SEEN this in Biology class insted of reading about it. Reply @s.abirami8394 2 years ago (edited) Small process in tiny organelles we can't able to see that naked eye .....precised And does the work perfectly. It's hard to beleive that all these things takes place in our body it's wonder thing but this the proof that human beings are alive today 🥺 Reply @nunodfes2 3 years ago Very well explained. Great work. I wish this existed when i had my biology degree back in my University years lol. At the time this seemed much harder to understand than it actually is 2 Reply 1 reply @youtubestop3346 1 year ago (edited) Its weird to think that even our bodies use what is essentially a spinning wheel to generate energy like we do in power plants. It really shows how we love to mimic nature even unknowingly sometimes Reply @kundanr5696 4 years ago Well i dont know anyone noticed that background music was like We are really travelling cell world . It is great video and made my day by its music Reply @ashoksonawane5050 3 years ago Lovely video @from great India 1 Reply @juzy1022 4 years ago this video is blowing my mind away Reply @MirjamMoutaj 6 months ago This video is amazing, thank you! Reply @mokshadavernekar8178 2 years ago Wow...very nice explanation😍😍 1 Reply @ghulammustfa9217 2 years ago Very good explanation thank you so much❤️ Reply @danielduarte5073 10 months ago Outstanding information!!! Well done!!! Reply @alejandrotorres1191 3 years ago OMG!! THIS IS THE BEST ANIMATED VIDEO!! Reply @karkleswhitevans 1 year ago Gustavo Fring found his new calling in cellular biology. Reply @betula-pendula 11 months ago It is so fascinating!! I nearly can't stand it. 😳 Unbelievable fascinating!! Reply @Mohammed347AA 1 year ago تحية من كلية مزايا الى جامعة هارفرد ، بوساتي 😘 Reply @miguelcalvo2541 1 year ago The mitochondria is the powerhouse of the cell Reply @MiG-17 2 years ago This makes me remind when i was in high school! Nice video. Reply @dalmamartinovic8371 4 years ago Outstanding animation and narrative. Reply @mikasaackerman-u4n 3 months ago MITOCHONDRIA IS THE POWER HOUSE OF CELL . now i know well 1 Reply @aztecburn115 1 year ago The ATP synthase membrane portion isn't called F0 but Fo by oligomycin the inhibitor Reply @ManyHeavens42 1 year ago I believe through Electrons We can cure stop Oxidation Some kind of Electric field. Just learned Air grounding. That took me 2 Years. On my own. Quantum Salt year and a half. 1 Reply @ollipolli6325 2 years ago Amazing and incredible job to do such a video !!! Reply @AlanCostaPlus 4 months ago Can't believe this is only ad based content and that it is already 6 years old Reply @sparttin117john 2 years ago This is a lot more interesting than what was in school. Reply @NeonsStyleHD 2 years ago Fascinating. Makes you wonder how life came up with this in the first place. It all seems to depend on each other. 1 Reply 1 reply @Trathaal 2 years ago Mitochondria gameplay: haha powerhouse boi Mitochondria Lore: Reply @bikram4you 2 months ago Thanks for the video....I finally know how oxyegen turns into water in our body Reply @motalabhossan381 3 years ago This is real education 1 Reply @morritzmiller3863 2 years ago have you considered making a video of the membrane transit animation but with lo fi beat to study too? it would drive up engagment. 1 Reply @mqttia-1924 11 months ago well animated thank you Reply @chrismathewjoseph1283 3 years ago Nice animation... Made my lyfe much easier thx❤️👍 Reply @ranimeher1725 1 year ago Superbly explained💕 Reply @chaosevolution 1 year ago Clear & concise. Thanks. Reply @Cup_of_tea424 3 years ago that was... amazing. just imagine how HUGE this is... like... hundreds of these power plants for each part of the mitochondria... and then that means each cell in the human body with a mitochondria can do this ... each cycle produces 32 atp.... IN EACH CELL... and those power our whole body! Reply @Beonrightside 2 years ago thank you so much we need more videos like this which make science more understandable Reply @WideCuriosity 7 months ago Flabbergasted that the human race can work out/discover this level of understanding. An interesting recommendation from YouTube. Reply @MichaelHarrisIreland 3 weeks ago Thanks, great video. Reply @evanquinn6092 4 years ago This was an amazing video, you didn’t skip info and make it confusing thank you Reply @Rayoulastreet 2 years ago this is just simply beatifull Reply @yashar9844 4 years ago what a beatiful system and amazing animation. thank you sooooo much Reply @ambermalik787 3 years ago Brilliant animation, great contribution for spreading knowledge among humans, marvellous. 👍👍 1 Reply @jimpaine6331 6 months ago What a fabulous video! Reply @brucejohnson5786 3 years ago Dude this just blew my mind. Thanks, it really clears things up Reply @tallbillbassman 1 year ago I believe you are missing something. This is a quantum-mechanical process, so we are looking at waves. All these structures are essentially shapes of three dimensional potential functions which guide the waves, just like a radio antenna, so that they interact in suitable ways with electrons and protons. It's not a pinball game, it's a radio show! What evolution has created is a very sophisticated version of transmitters and receivers. Biochemistry is evolved radio engineering. Reply @myatthuswe6093 3 years ago incredibly amazing animation video helps me. thanks Reply @stephenarmiger8343 2 years ago It would be amazing if we humans could both teleport and shrink our bodies wearing a cellsuit , rather like a spacesuit , and explore the cellular universe. 1 Reply @reahthorolund8373 1 year ago I wouldn't usually swear on a channel or video like this, but that... was fucking insane, and fantastic. Wow. Reply @benjaminrumbewas4057 1 year ago im hooked for several minutes till the narator hit us with "The Reason We Breathe Oxygen" Reply @gilsai4990 8 months ago wonderful explanation! very helpful :) Reply @idegteke 1 year ago Whatever kind of sub-atomic particles build the atoms in this video up, they create atoms that look utterly simple and identical but, as soon as they start to meet with other atoms RANDOMLY (as we call it) and form proteins etc., they start to build structures that we can now see visualized making highly organised and unexpected things including multiplication – and, therefore, produce ideas like the one I written down in this comment. I must attribute this idea, too, to the particles that build my special atoms up to communicate this message. Reply @-eu3xx 1 year ago Being a neet aspirant i loved it. Reply @MrZooganopolos 3 years ago That was a lovely and descriptive review! Thanks for taking the time to make such a great video! Reply @mafazabatool5234 3 years ago This is making me feel alive... Omg this video is mind blowing 🔥 Reply @sonalisonar2333 3 years ago (edited) Just .. incredible keep doing more videos from 🇮🇳 Reply @ummesulaim5949 3 years ago This is literally the best video up there❤🙌🏻thankkk youuu so muchhhh Reply @Neet-fy9ch 4 years ago Most amazing video ever watched Reply @Dazzletoad 10 months ago Absolutely magnificent :D Reply @4E414D45h 2 years ago This factorio run is crazy Reply @fierrots 3 years ago lot of approximations here... FADH2 is boud to Complex II. Succinate is the electron donor of CII. The odixizing site of CIII is not well on the intermembrane face. etc Reply @ishan0369 4 years ago Best Explanation of ETS!!! Reply @SB5SimulationsFerroviairesEEP 3 years ago Merci de l'échange! Très intéressant! Stéph. Reply @aasansathyamoorthy 1 year ago Excellent video.Thanks a lot. Reply @gyurendakke1984 3 years ago God, the ETC always confused me, but this amazing video made it so clear. Thank you. Reply @Uruba_Rais 2 years ago great.. help in visualising and understanding Reply @nithichotechongrungruang3778 4 years ago Thank you, we're all very grateful of what you did. Reply @DebashisChoudhury-ff4cs 2 weeks ago Thanks it was really helpful ❤❤ Reply @baraskparas9559 1 year ago Great presentation Reply @jupitereuropa-e3w 4 years ago I want more animated videos like these! Reply @didijaja8973 1 year ago Thanks a million for this video Reply @Rajibuzzaman_STEM_Rajibuzzaman 11 months ago " THAT'S WHY PSHYSICAL ACTIVITIES UND DUE INTAKES MAKES THE DIFFERENCES " A COURSE ON REJUVINATION Reply @abidkhan1081 3 years ago AMAZING AND EASY TO UDERSTAND EXPLAINATION Reply @lukaschumchal1001 4 years ago Just amazing and very usefull animation . Thank you. Reply @boson2916 2 years ago Amazing! It's less than a microsecond's job begins with the breathing. Reply @ramadhanoruch8463 2 years ago Fantastic explanation.. Reply @atmanbrahman1872 2 years ago Marvelous design. Reply @rutujagore1483 4 years ago Really suparb animation. It make visualize the things 👌🤘👍 Reply @aurora2319 3 years ago AMAZING clear and understandable video! Reply @diyaroy7187 2 years ago Owo that's amazing. I am a new visited of this channel. But I'm love with it Reply @aniketdas7803 1 year ago Just wonderful ❤️🔥🔥 Reply @audreyanderson7042 3 months ago Question: If complex II doesn't harness that energy from the electrons skipping redox centers, what happens to it? Does the energy stay with the electrons until it gets to complex III/IIII or maybe it helps shuffle coenzyme Q along? Reply @markie9739 3 years ago Simply WOW, thank you so much for this video! Reply @doreenbachmann5508 3 years ago beautiful video and lovely voice thank you! Reply @kafiamir7129 10 months ago And to think Allah has created us with all this perfection that not even an electron jumps anywhere else other than its destined redox centers. That promotes proton pumping and that promotes synthase rotation which promotes ATP synthesis. SubhanAllah❤❤ how can we think that Allah doesn’t care about us? Reply 1 reply @HealthyThinkingsubstack 5 months ago This is quite excellent but it should’ve been better. If this was produced six years ago in 2018, then they should’ve included mention of supercomplexes. If they wanted to go farther, they could’ve talked about nutrition in more detail. Reply @VileVictour 2 years ago I was scanning random qr codes I convergence station in Denver and this was one of the video's Reply @nikhatreena2461 4 years ago Out of world work,,such a hard topic explained in a cool fashion,,kudos to your work and thank you so much 🔥🔥 Reply @deivasigamanisundarathatha5202 3 years ago Wow.. Very valuable information. Reply @Mateo-jc9zg 2 years ago amazing video, keep up the great work! Reply @slehar 3 years ago Just extraordinary at so many levels! Reply @lastyhopper2792 2 years ago This looks soo fun... I want to know what aspect of those system can be optimized and fine tuned Reply @anonymous._._._. 4 years ago Most amazing video 1 Reply @WaterproofSoap 3 years ago Imagine building a progressively complex video game model based off of this animation and making it available to children Reply @lukehelpmetakethisdangmaskoff 3 years ago If you are an Evolutionist, and we were hiking together in the mountains and I overturned a rock and found a paperclip, there is not the slightest chance in hell that I could convince you it came into existence by random processes. Yet you believe, that what is the subject of this video, did come about by random processes, and there is not a chance in hell of convincing you otherwise. I find that truly bizarre and heart breaking at the same time. 1 Reply 1 reply @persiancarpet5234 2 years ago Eating and breathing while watching this video in order to keep these processes going! 1 Reply @rebecafreitas5061 3 years ago Wow, thanks for this great animation! It's fantastic Reply @severest75 3 years ago Great video! Aweinspiring.Does anybody else think it's kind of hard to imagine that all these complex mechanisms came into existence just by unguided, random and blind processes? 1 Reply 4 replies @ruki25 3 years ago When they said Mitochondria is the powerhouse of the cell, I didn't think it was literally powered by the flow of something spinning what is essentially a turbine of sorts Reply @blazednlovinit 4 years ago ATP is a fascinating molecule in the way our biology uses it. It's like a nice little prepackaged battery ready to go :) Reply 1 reply @busraertas7381 3 years ago this video is exactly what i need. thank you!! Reply @mariovelez578 4 years ago I just like seeing these animations Reply @sl5311 4 years ago This is extraordinary. 1 Reply @khushboobadgujar358 3 years ago Such as a great clear explanation Reply @L4v4molly 2 years ago Fussilat 41:53 سَنُرِيهِمْ ءَايَٰتِنَا فِى ٱلأفَاقِ وَفِىٓ أَنفُسِهِمْ حَتَّىٰ يَتَبَيَّنَ لَهُمْ أَنَّهُ ٱلْحَقُّۗ أَوَلَمْ يَكْفِ بِرَبِّكَ أَنَّهُۥ عَلَىٰ كُلِّ شَىْءٍ شَهِيدٌ We will show them Our signs in the horizons and within themselves until it becomes clear to them that it is the truth. But is it not sufficient concerning your Lord that He is, over all things, a Witness. 1 Reply @explorenature8802 3 years ago Very fruitful.Thank u Reply @ritisha9865 3 years ago Didn't understand very clearly but video was amazing 👍 Reply @sarafernandezfuente5168 4 years ago it helped me to understand better this proccess that sometimes is hard to memorize! Reply @germgoblin5313 1 month ago Am I the only one who feels existential dread watching this? 1 Reply @defeatSpace 2 years ago They're like specialized little computers that all maintain one organism. 2 Reply @yleniamafodda9347 1 year ago beautiful metabolism Reply @oldsteamguy 2 years ago breathtaking Reply @lucasatsuo123456 3 years ago Oh yes, the powerhouse of the cell Reply @hikolanikola8775 4 months ago why is there no more research done on this topic?! 1 Reply @christianherdt2932 3 years ago Großartig, ich bin begeistert. Best wishes from Germany! Reply @guillermolopezlluch3065 6 days ago In complex II there is a minor mistake. It seems that FADH2, as NADH is soluble but it is not. Is succinate that transfers electrons to the resident FADH2. Reply @ruchirlawate624 2 years ago Brilliantly clear, thank you! Reply @logandefreitas1416 3 years ago this is sooooo frickin helpful Reply @jainsanskar722 11 months ago Very helpful thank you Reply @linubindhuprakash912 2 years ago Awesome work ... Thanks a lot🌠 Reply @flavaa9494 3 years ago once again youtube saved my life Reply @KerriWest911 4 years ago This is beautifully done and informative. Reply @bertdog7639 3 years ago It is amazing to me that we can figure these things out. The real question is, are we really sure that this is how things work? Reply @NeogreenPeaches 2 years ago How does the NADH end up in complex 1? Or is there so much NADH just randomly zipping around that it accidentally finds its way in? Also how does Coenzyme Q move? These questions apply to each of the complexes for their respective inputs and outputs. Also in complex 1, do the protons get attracted to the green blob shown because it is high energy? What is the mechanism that pulls them in and forces them to the other side of the grid? 1 Reply 2 replies @reshmavats8970 4 years ago Thanks 1 Reply @LuaanTi 2 years ago Just a small thing - it's F O, not F zero. Yes, it's a bit confusing with the other subunit being F 1 :D Reply @catmom1322 3 years ago This is terrific! I wish we had had something like this when I was i n grad school, but I'm thinking some of this may have been discovered after I graduated. Either way, I'm loving this! 1 Reply @chrisly2775 3 years ago This is so cool. This is why I'm going to be a medical illustrator. Reply @shelan7058 1 year ago 5:42 what does Complex II do with the energy then? 1 Reply @TSUKI_3. 2 weeks ago So what do complex 2 & 3 do with the energy they get from the redox centers if not pumping protons? Reply @leonidkerchev4256 3 years ago Impressive! Thanks a lot for the great animation! Reply @c00lguy94_ 2 years ago Cool visualization, looks really weird and detailed Reply @johannamarianfinos9781 3 weeks ago best video ever! Reply @bettyswollox8020 1 year ago Amazing. Thank you Reply @paulakandjeke9576 3 years ago Thank very for explanation Reply @غزةستنتصريارب 2 months ago (edited) Praise Alleh that He is all wise!. From Yemen. Reply @nosegrindv4951 4 years ago Truely we are fearfully and wonderfully made! Reply @CaptainSteve777 8 months ago It all looks like an elegant design to me. ;) Reply @robertzeurunkl8401 3 years ago 4:05 - What is being described here is literally a lightning strike - following the path of least resistance - made up of individual electrons. Microscopic cellular lightning. Now you see how we are parts of a larger organism, following the same pattern on a larger scale. And, probably, our entire planet itself also part of the same continuum on a galactic scale. It's all one life form from the entire universe, down to individual atoms, and probably even deeper than that, if we could look that deep. 1 Reply 2 replies @phydonne 3 years ago Cuando leia un libro de biologia no le entendia nada sobre la cadena de transporte de electrones. Pero con este video me parecio mas entendible aunque demasiado tarde ya que en ese entonces no sabia nada de ingles fue como hace 7 años. Reply @nishgupta8741 3 years ago U taught us superb....sirr.. Reply @Captain.Mystic 2 years ago It feels wierd for it to click that the protons are pumped through the chain because of normal electromagnetic rules on a tiny scale like this. The redux centers are literally an atom thin wire being an inductor(think a powered copper wire) for protons to be attracted to like a magnet. Reply @vithalbhaipatel1013 2 years ago Well show. Good information. Well. Reply @mattphorwich 3 years ago Great video! Such a majestic amazing process! Reply @mehakjan9140 1 year ago Masha Allah 🤍 C how beautifully , amazingly, exquisitely ...Allah created everything ... SubhanAllah🤍 Reply @darkmoon3646 2 years ago This is so damn complex, thanks for the animation Reply @shashidharshettar3846 1 year ago I’m 68 yrs old MD. I don’t know how I passed all those medical exams using just memorizing Reply @melisakoruk6864 3 years ago thank you for great explanation Reply @memogap88 2 years ago Also complex II does NOT use Energy Liberated to Pump Protons. Is Energy HEAT and if so what regulates the HEAT if not used ie. dissipates without causing adverse - unintended altering effects? Reply @anglesmith4840 3 years ago This is why I believe people like Dr James Tour. Reply @AZ-qx1xd 4 years ago This is amazig! I am very thankful!!! Reply @wanderlustexcursion 3 years ago Beautiful explained Reply @oneistar6661 2 years ago Let's speak about this perfectly tuned machine and it's origins. 1 Reply @usaidmahmud3964 3 years ago This helped so much, thank you!! Reply @Classyangelic 4 years ago thank you! This has supported my learning! Reply @shinn-tyanwu4155 1 year ago Great lecture 😊 Reply @CurlBro15 3 years ago When you think about the laws governing the quantum fields in this interaction, and the complexity of those laws, it’s beyond insane to think that all of this is really happening inside our bodies! 1 Reply 3 replies @idegteke 2 years ago This makes me think that a living cell is literally full of procedures that could no way be developed evolutionarily (using successive approximation by lucky strikes) simply because they have never had the chance to genetically compete with their somewhat less functional counterparts, given the fact that their ability to function is either 0% or 100% depending on whether the genetic code that shaped them from scratch created them the exact way they should be position to function or not. Reply 1 reply @NK-wf1bu 4 years ago ThaNk u soo much, very helpful👌👍😊 Reply @dogchaser520 2 years ago I think it's kicking in 1 Reply @lakshmimadhavan5448 3 years ago Super explaining Reply @victormaxwellpeters9771 1 year ago (edited) In which form the energy is released when an electron jumps from one redox centre to another?? Is emf induced by moving electrons?? Reply @fritsgerms3565 3 years ago marvellous. as the modern view is that electrons are excitations in the electron field, I find it very hard to visualize the processes that are shown so nicely here. I wonder how accurate this visual animation is. Reply @dingdong6259 2 years ago (edited) so we have an 200 rpm - ohc motor with the camshaft opening and closing an atp synthese and propulsion system? (how) does it sort out atp between "loose" and "tight"?? Reply @malorie1042 3 years ago Love these videos. So so so much easier to understand & learn. Reply @milicejunior2203 1 year ago Eu me rendo... Tecnologia de ponta. Whau ! ! ! ! Reply @maazullah5492 2 years ago very helpful video ☺️ ❤️ Reply @patldennis 3 years ago (edited) My suspicion is that aerobic metabolism started out as a means of detoxifying the oxygen pollutant that photosynthetic organisms were pumping into the atmosphere and it was eventually coopted through evolution as a means of producing ATP. Reply @omarelkhateeb6269 1 month ago Impressive , thanx Reply @claudias895 2 years ago I just scanned this QR code in Meow Wolf Denver 1 Reply @yverteatoko5960 3 years ago Very good video. Reply @fatimafunes7009 1 year ago Excelent. Thank you!!!! Reply @sachielguluma5519 1 year ago i don't even do anything biology related, this is just interesting. Reply @Nani...nandagore 1 year ago Thank you so much🥹 Reply @johnhoward6393 1 year ago The molecules are sentient but extremely limited in what they can do. They are precise and super reliable. There are more things, Horatio, than are dreamt of in your philosophies. Reply @rosilenerebeca5623 2 years ago (edited) There are a mistake about F0 protein. Is FO (letter o) protein due your inhibition by oligomycin and therefore is not Fzero. Reply @austindolan3142 2 years ago Im taking biology right now, and after learning about cellular respiration I watched about this, I wish I had seen this before taking that test lol Reply @asicerik 2 years ago How in the heck was all this figured out? Amazing stuff 1 Reply @drewfisher1619 4 years ago To consider that these sophisticated machinery works in our body without us even thinking. Reply @melaniemansir3173 3 years ago Thank you so much!! this was brilliant Reply @jackasotarex 1 year ago Thank you so much! Reply @behayluyibe7652 2 years ago Thank you very much I feel your effort Reply @the81kid 4 years ago Nicely explained! Reply @harrrytoool1391 3 years ago (edited) This is a brilliant explanation of the energy creating process. There’s only one confusing.com part. In Protein complex 3 and 4 the colour of the hydrogen atom in the water molecule and the proton atom are the same. Correct me if I’m wrong as I need to understand, I guess we need oxygen to mop up free radical electrons which steal electrons from genes and other molecules therefore stealing other molecules and genes functionality. Fascinating. Reply @edavivia 3 years ago If you calculate the number of protons in using the size of mitochondria at physiological pH, you would know there are approx. 10 protons within a mitochondrion. There are millions of these respiratory protein complexes which are purported to "pump protons". Oxygen is very diffusible and hence the idea that it would be present solely at Complex IV to make water without any interaction with other protein complexes seems too deterministic of a scheme to happen under normal physiological conditions. Also, the whole scheme of pumping out protons to generate a TMP in the intermembrane space while assuming that the outer membrane is impermeable only to protons while allowing much bigger atoms through also seems unlikely. The whole scheme has also been shown to be thermodynamically unfeasible by recent publications. It is high time we look beyond chemiosmosis, electron transport chain and rotary ATP synthesis. Reply @memogap88 2 years ago min 6:27 is it correct to state that 4 electrons turn one O(xygen) to two molecules of (H2o) water ? Surely this could have been stated better. Reply @dvuono1 3 years ago Complex I and II are mislabeled in this animation. Complex I is the transmembrane protein (labeled complex II in the video). Reply @NebelmondDso 5 months ago In which form is the Energy of the Electrons between the redox centers passed on? Reply @ezyloka 1 year ago wish i had this in school Reply @BenjaminHaukaas-l1t 1 year ago Very good!! Reply @gregorysagegreene 1 year ago (edited) It strikes me that there's a cobbling together of various gradually-improved energy-harvesting paradigms, all to supercharge the gradient, with oxygen being the latest enhancement. And again, ATP synthesis gets better with each newer step, until you finally have that torrential gradient driving that sophisticated synthase to get the hyper-production of ATP required to support eukaryotes. One wonders if a technological redesign might be simpler, more efficient, and open up vast new possibilities for life than 3.8 by of competition for energy capture. We could have a new super species, and dramatically increased industrial power too. Reply @zack_120 3 years ago If added the detailed electron transfer processes at the sub-/atomic level, it would be extremely more interesting and help understand ETC. Reply @mahparariaz4965 2 years ago Fantastic the best in biology Reply @12Monkeysable 4 years ago Thanks a lot. I use it in german "Higschool" for my students. Reply @divyanshkatara7553 1 year ago What is flip flop movement of UQ and lateral movement of cytochrome c. 1 Reply @AndreasHLux 4 years ago Wow, thats an very important answer of a question i hav had to the real-systematical DNA/RNA reduplication. Not very specific for the molecules Type, but a bone of reasoning. Thanks a lot, ... ima pleased to watch the more others animations you made. Reply @PlateletRichGel 2 weeks ago Why do i get vivid dreams when I take Coenzyme-Q? Is it the better activity of electron transport in my brain cells. Reply @12fold 1 year ago Project Orion used pop bottling tech and so does the ATP molecule. Reply @bengipolat3791 3 years ago Such a great video thank you it helped a lot Reply @glud2292 3 years ago めちゃくちゃ良い動画 1 Reply @blazednlovinit 4 years ago In the UK we have replaced the mitochondria in a fetus of a mother with a mitochondrial disease before, creating the first human made from the DNA of 3 people (1 being only mitochondrial DNA, but still) Reply @rimal9305 3 years ago this is fascinating Reply @faisalkhanlucky2732 3 years ago Best explanation ❤️ Reply @josepiratilla 7 months ago I can’t avoid feeling like seeing the teaser trailer of Factorio II. Reply @dy7296 1 year ago No I'll no longer question why strands of DNA require several hundred million years to turn into prokaryotic cells and another several hundred million years for the first eukaryotic common ancestor to appear, which was theorized that sometime around 2 billion years ago, a larger prokaryote merged with a mitochondrion which used to be an independent lifeform. Reply @malkeus6487 2 years ago You were so close to meme territory with that power plant comment. Reply @AmaraofEarthWithTheLavaCore 1 year ago (edited) What is the energy generated from complex 2 used for then? Reply @laurarebecajimenezgutierre78 5 months ago great video Reply @hellohellogoodbye9327 2 years ago I wish our hod Mam is like you.. U r so beautiful mam I understand this topic very easily 😇🤗 Reply @M0rquer 4 months ago i watch this kind of video only because i like biochemistry, i don't need it yet, i am in 8th grade of school 1 Reply @TheStarflight41 3 years ago Intelligent design couldn't be more obvious. Reply @Brightsider1 2 years ago What an amazing video! Reply @miray3663 6 months ago it was great, thanks Reply @lias57 4 years ago Intelligenz Design, fabelhaft. Reply @droidsuperuser 7 months ago Which Energy form does complex use to pump proton? Reply @johnal5888 4 years ago Amazing, great work Reply @Ken-rq9xr 4 months ago There's obviously intellectual understanding of the quantum mechanics in individual cells. Where you put your eyes.😮😮🤓😽🦜👍 Reply @Daniel-xh2xf 1 year ago At 4:25 we see the electron transfer between redox centers releases energy, which in the case of complex I is used to pump protons. At 5:31 we see the same phenomenon occur in complex II so we would expect the same release of energy, however here this energy is not used to pump protons. What happens to this energy? Reply @memogap88 2 years ago AT MIN 4.27 : A SMALL AMOUNT OF ENERGY IS RELEASED AND IS HARNESSED ? this needs to be elaborated on with possible an addition clip doing further explanation?? Reply @barry7608 2 years ago A bit over my head but extremely interesting, thanks. Would it be fair to say this is an electro mechanical process, you did say the proteins are made to rotate? 1 Reply @tiffany5333 1 year ago Thank you Reply @celsaprado4185 3 years ago Thank you. Reply @aartisahu6182 3 years ago Very useful thank you so much Reply @alessiatoma4556 7 months ago GOD BLESS YOU 1 Reply @Stamnessj 9 months ago How would changes in cell membrane fluidity and permeability affect this process? If monogastric animals, such as humans, increase intake of omega-6 polyunsaturated fatty acids, it will change both fluidity and permeability of cell membranes. This video made my head go into high gear. Reply @turinmormegil7715 4 years ago When you say the lack of O2 means halt in the ATP synthesis, is it because the pumping of H+ (8 molecules = 2 Water + 4 protons, specifically for Complexe IV) won't be completed, thus nullifying the constantly kept gradient or simply because, before the gradiente suffers, there won't be enough H+ to move ATP Synthase? If so, but what abbout the protons that were already pumped by complexes I and III into the intermembrane spcae? They don't need Complex IV to finish their own pumping. Reply @YunusEmreCevheri 6 months ago Very good Reply @uroojrajaakram3079 1 year ago Thanks a lot ❤❤ Reply @DaeZey 3 years ago Can anyone tell/point me to a video explaining how complex I uses the energy from the redox centres to pump protons? 1 Reply 1 reply @vipl7025 3 years ago Wonderful 1 Reply @jupitereuropa-e3w 4 years ago Well societys of any kind are like cells to, working hand in hand to grand reproduction, energy gathering, protection and many other tasks. 2 Reply 3 replies @genathaimed2828 2 years ago beautiful video :) Reply @GrixM 6 months ago Are all the complexes necessary? If so, why? Why do we need to breathe if only complex IV requires oxygen, cannot complex I and III just do the pumping instead? Reply @UpdateTV2448 10 months ago Outstanding Reply @UmarFarooq-ss7os 5 months ago All this is clearly evident on the existence of One God who is magnificent and merciful Reply @Starfire777 2 years ago GOD our creator is AWESOME A powerful DESIGN!!! 1 Reply @MrSlovanprofessor 4 years ago Great video crazy music - drives me nuts - Reply @heba5835 1 year ago Really perfect💕💕💕💕💕💕 Reply @nightshade2826 2 years ago Hello, I have a question, at the start of the video we are talking about protons floating around but aren't protons a part of an atom's nucleus? How can they possibly be free from it? Maybe I am misunderstanding this because eng isnt my native language. But I am very confused. Reply @mr.quietff7072 2 years ago nice class Reply @罗巧 2 years ago This is so helpful! And I wonder in anaerobic conditions would the only difference be terminal EA. Reply @hussainal-daheri3134 1 year ago thank you so so so much Reply @phatpoint 2 years ago Nice video! Reply @LalaFilmes-f8q 1 year ago Obrigada você realmente me ajudou muito 😄 Reply @BushCampingTools 4 years ago Wow great video for learning about the etc! I've subbed! I never had anything like this at uni. Reply @omsingharjit 4 years ago (edited) Who engineer such mechanism 2 Reply 1 reply @-_Nuke_- 1 month ago Im confused, are these things inside the mitochondria? Or outside? Reply @spacelemur7955 2 years ago Is it fair to assume that the different complexes that harvest electrons via different routes have all evolved separately (and even are the winning methods, less efficient alternatives having failed to compete successfully)? Reply @sujeetpatel-hk7vh 1 year ago Amazing 1 Reply @issakhan100 4 years ago Great animation! but Complex 1 should be penetrating the lipid by layer fully, while complex 2 penetrates only mid way. Reply @Muslim_5566 1 year ago I appreciate your animation but 1 mistake I see in it that the complex 2 actually is an extrinsic protein, but in your video it is shown as intrinsic protein, which means that, It is not through-and-through to the inner membrane, it is only attached to the inner side. Reply @konstantinmymind180 2 years ago But how dose coenzyme Q know where to go. Is it that it goes to the compound nearest to it and why dose it not go back to the same compound Reply @DanielleAdamstranspride 1 year ago Mew mew needs a lot of help with cellular respiration and genetics. Hope I pass the class too. Reply @adelabrouchy 1 year ago And all this wonder for us to be able to be alive and discussing about life in Internet. 🌻🌻🌷🌷🍀🍀🌼🌼🌳🌳 Reply @shanthala1345 2 years ago What does complex 2 use the energy for Reply @CloudScience 2 years ago Thank You Reply @septemberamyx 2 years ago Excellent Reply @astharajput390 7 months ago Best video 😮 Reply @yogastakurukarmani 4 years ago We r so complex n sophisticated... Bow down 🙇🏻‍♂️ to nature's intelligence 1 Reply @samruddhigarade2098 3 years ago Thank u so much for this vid🙏❤ Reply @HawthorneHillNaturePreserve 3 years ago Excellent Reply @johnbates2709 3 years ago Excellent Reply @kiranmadduru9099 3 years ago Excellent Reply @tarka38tara34 4 years ago amazing work !!!!!!!! Reply @rolandovelasquez135 3 years ago Wow. And to think that all this came about by dumb blind chance. Evolution is so intelligent! Reply @michaelrowland-us3he 4 months ago Where does the water in cellular respiration go to? Reply @eatandrepeatt 4 years ago (edited) Thank you so much Sir This video is amazingly epic.... Pls keep uploading that type of videos for us...... Thankful......🇮🇳🇮🇳 1 Reply @timofeybobakov3628 3 years ago Okay, so if the Complex I uses energy liberated from electron jumps between redox centers, that energy is used to pump protons. But, Complex II does not use that energy to pump protons. So, where then does this energy go? My guess, Into jumpstarting the movement of Coenzyme Q , maybe? Reply @zaenaschannel 1 year ago absolutely bkasted and watching this video happy halloween-eve Reply @DanielleAdamstranspride 1 year ago I wonder why I can't get hit with browser hijacks for things like this and basics to Calculus and other things that will help me through college. Reply @ematthews6642 1 year ago If I am being asked to define the three main energy carriers in this process, is that the protein complexes 1, 3 and 4? Please can someone tell me if I am correct? Reply @jengoweekes2841 4 years ago H+ ions moving due to concentration gradient, biochemistry is so cool Reply @Kisyov 3 years ago Stunning! Reply @frida1658 1 year ago what are the purple things at 6:35 please help I have a midterm on Friday and it is sending me into cardiac arrest not knowing what those purple structures in complex 4 are Reply @ghulammustfa3059 2 years ago Thank u soo much sir❤ Reply @ilimselyardm9698 3 years ago MashAllah , SubhanAllah thanks great video may Allah bless you Reply @pabletediaz 4 years ago Life is a natural miracle. Reply @manojy5876 2 years ago Amazing 🥂 Reply @interestingcuriosity546 1 year ago You just got to appreciate evolution and nature.I mean, an electron is the most abundant in the universe,but mostly tricky.Quantum mechanics says we cannot know both the speed and location of the electron at once.But living systems are able to even harness the energy from these very electrons! The very electrons that form the structures of atoms which make up the universe...Hmmm, weird....Just weird 1 Reply @adamc8627 2 years ago i got my bio degree in 00...this is magic. Reply @pallavi07100 4 years ago This is amazing ⭐️ Reply @stoichiometryc8462 10 months ago So this is an actual video for the prestigious Harvard University... with a lower case title Reply @SolveEtCoagula93 2 years ago I have SO many questions! But, can anyone tell me how the liberated electron energy in Complex 1 is 'harnessed'? I mean, the electron loses energy (is this a quantized, or a translational amount of energy?) but exactly what form is this energy in, and where is it stored in order to then be harnessed? My sincere thanks to anyone who offers help! Reply @MBison-im2qy 3 years ago (edited) In Complex #4, a reaction of 4 electrons converts a molecule of Oxygen to 2 molecules of Water. Please explain that. Reply @UTtherapy 3 years ago I almost couldn’t keep up! Reply @ad786ify 4 years ago Thank you 👍👍 Reply @wjwjnwnjwjw 2 years ago Best one💥 Reply @uremcolo9489 1 year ago Please what does complex 2 used the liberated energy to do? Somebody help 🙏🏾 Reply @omsingharjit 4 years ago How can bare protons exists just by chemical reactions ? 2 Reply 2 replies @RariaRoyal 6 months ago Meow wolf in Denver sent me here for some reason! Reply @kaushamvisingh114 4 years ago 👏👏👏👏👏👏👏woooowww best video of ets may god give u more success Reply @Т1000-м1и 3 years ago This university: hey so we ma- Schools: no 2 Reply @jimibb4216 4 years ago thank you Reply @medicallabtech7993 4 years ago simply amazing!! Reply @laylachemist5245 4 years ago Well done Reply @Jere616 4 years ago Since the main work of the chain is to put protons into the intermembrane space, why are the 4 complexes called the electron transport chain instead of the Proton Pump Complex? Reply @1eingram 3 years ago Can nadh and fadh also synthesize atp from fat and or ketone metabolism? Reply @davidtompkins5000 2 years ago We are wonderfully made. Reply @Marco-xz7rf 2 months ago so what frequency should i pllay to my body in order to get electrons to flow in my cells and drive these complexes without nadh+? I mean this somehow should be possible? Reply 2 replies @fredrick443 4 years ago Haha. How dare you put this in my feed, YouTube! I get enough of this at school! Reply @Spindily 3 years ago RIP Professor Lue 1 Reply @averycarman5645 4 years ago My 7 year old son just watched this for the first time and he loved it!!! He wants to know what other videos you have to explain how cells work? 1 Reply @feliscatus4921 4 years ago This is so useful! Thank you:) Reply @tonyarcus 11 months ago Nice video. However, all the atp produced is inside the mitochondria, how does the rest of the cell, outside of the mitochondria get atp to do their work? Reply 1 reply @iloveamerica1966 4 years ago That was awesome! Reply 1 reply @إيناسموسىبوبيري 1 year ago What is the end product from this process? Water or oxygen???? Reply @Athenoi33 5 months ago In my head is like "how can it not be a higher intelligence that made these complex network of parts inside other parts?!" Reply @woocash2526 7 months ago Wow! Just wow! Reply @bhagya2010 1 year ago thank youu😍😍 Reply @livefortheweekend420 3 years ago Great animations. A little bit out of my realm of understanding but interesting and informative nonetheless Reply @shreyadas6453 4 years ago Thanks for this vedio Reply @leggy12 3 years ago There is an inaccuracy in the commentary. It says NADH and FADH2 are a byproduct of sugar metabolism, whilst this is true they are also a byproduct of fatty acid metabolism, Ketone metabolism, and amino acid metabolism. In fact, at rest, we use far more fatty acids to produce these molecules than glucose. Reply 4 replies @NdendahayoJeanclaude-kk2go 1 month ago Hello, i am from RWANDA ,i wish to get educated in HARVARD MEDICAL school , how can get in touch of it , help me please . Reply @sophieodallaire476 2 years ago How didn’t I found this video before my biology exam😭 I failed and got 48 1 Reply @diwu4125 1 year ago Amazing！ Reply @timothyborys916 1 year ago In complex-4, so water is one oxygen and 2 electrons? There should be 2 hydrogen molecules and 1 oxygen to make water. Can someone explain? Reply @prestonburton8504 9 months ago where do the 'proton's come from? I know they are simply hydrogen that has the electron removed. They must be from water but how does our amazing systems break down the water molecule (which is so hard to do) to release the hydrogen atom. Then how does this electron get stripped? anyone? 1 Reply 1 reply @maajidsyed2847 11 months ago (edited) 4:35 Energy is harvested by complex I to pump protons. what is the form of energy released by an electron moving through the redox centers of complex? and how is it used to pump protons. What happen to the proteins that they start pumping protons? Anyone Reply @awsomedude1011000 2 years ago There was a QR code in a meow wolf and it brought me to this video. Reply @ThatOpalGuy 1 year ago utterly astouding. Reply @hlaakaplee 3 years ago aww cute lil electron probability cloud probablizers Reply @christopherleubner6633 1 year ago Inagine the incredible possibilities if someone could hack this molecular machinery to synthesize complex organic molecules super efficiently. 😲 Reply @cristejada1186 3 months ago So in other words we have atomic power plants built into our own biology? 2 Reply @smiggyballs4100 1 year ago does cyanide toxicity come from affecting this proton gradient? i cant find anything in plain english but i remember learning that cyanide works by shutting down mitochondrial activity Reply 2 replies @melissarainchild 4 years ago (edited) Thanks for posting, now... I "get it"... Reply @saisarvam4331 3 years ago Great sir Reply @michel.b5752 4 years ago So molecule entering complex I release 2 electrons, and become charged twice. What do they turn into ? They cannot stay charged for ever. Reply 1 reply @sidclark1953 3 years ago Phenomenal! Reply @firstnamelastname9918 2 years ago (edited) fun, fun fun! So the 4th complex was taking 1 molecule of O2, 4 protons and 4 electrons to spit out 2 molecules of water in to the inter-membrane space? EDIT: Oh! the energy from oxidizing(?) the hydrogen ions is used to move 4 additional protons as well? (I'm not in biology, just a curious software engineer / information junkie) Reply @AndreHypnosis 1 year ago No days off boys. We've got a body to keep running!🪖 Reply @jak8790 1 year ago How did we achieve this level of accuracy, evolution, maybe God, or what? this is a great design, a micro level of everything working in harmony, to keep us alive. I can't find the words to describe my urge, to know. Yet nobody else knows what is going on to help me understand. We don't know, even a fraction of the hidden truth inside us. Reply 1 reply @zahraan5070 3 years ago wow very simple Reply @jansigayan 6 months ago Amazing Reply @KCEPlad 1 year ago THE MITOCHONDRIA IS THE POWERHOUSE OF THE CELL! :D Reply @vioseven3799 3 years ago Amazing! Reply @calixtomelo1213 4 years ago Simplesmente extraordinário! ❤️❤️💎💎👏👏❤️💎💎❤️❤️❤️ 1 Reply @Turboy65 2 years ago (edited) OK, there's a lot I don't fully understand here but I know this: Free protons don't exist in cells. So it stands to reason that the protons that are flowing must be part of molecules. What molecules are the proton carriers? Hydrogen ions. So why not just say that? Reply @Signal6000 2 years ago Wow thats how the energy of food and sun is used in my body. We are a universe Reply @burhanbashir4950 2 years ago Thank u Reply @cheeseburger7925 1 year ago sounds like gustavo fring teaching about cellular respiration Reply @nusratjahan4922 3 years ago Thank u ...... Reply @marcorozo9922 3 years ago How they remove protons from the atom's nucleus isn't it bound by strong nucleus force? Reply @NaduaGarbe 2 years ago Meu Deus, que coisa fantástica.....!!! Reply @babinomrabti5019 4 years ago thanks mom for giving me the chance to get mitochondrias Reply @FlashproCrazy 1 year ago Amazing Reply @celinaandrade9918 1 year ago I knew Walter white was a chemistry teacher but I never never Gus was a biochem teacher !!! Reply @kukunishad 1 year ago It's really mind-boggling that, how we know this mechanism at atomic level??!! Reply @raulmartin1864 3 years ago It is not F0 but FO, because of its Oligomicyn sensitivity. Reply @charlesokeefe8788 2 months ago I do not realize all this, but I assume law of simple machines at work. My q is if Injest protein 1 day, then next couple of days carbs or something, does that protein intake last all 3 days. I ask cuz usa diets so processsed. Reply @abirbk8361 1 year ago thank u so much sir god bless you :) <3 Reply @gp235801 3 years ago RIP Prof. Lue Reply @sitalin2434 4 years ago Okay, The Human Body IS AMAZING....... Reply @dobariajalpa8680 2 years ago Amazing Reply @balapuramchalapathy4029 1 year ago beautiful Reply @SidAhmedKHEROUCHE-dl8mk 6 months ago like how can you beleive that this came out by accident . at this moment you're just being erogant and just won't admit that you were wrong . Reply @Snm-y5o 3 years ago Great got it ! Reply @dedo9777 2 years ago Does anyone know the name of the music? Reply @blobi. 2 years ago beautiful Reply @cynthia6514 2 years ago Oxidative phosphorylation Reply @Jequetepeq 1 year ago ATP synthase my beloved Reply @mohamedhegazy2139 4 years ago Wonderful.... Reply @triducle9527 8 months ago wow life is amazing Reply @FAGUNIAGAMING 1 year ago Why do we have more information than a Harvard video in our class 12 book 😭 Reply @arjunharikumar9040 2 years ago So if O2 absent then the electrons get accumulayed in complex IV? Reply 1 reply @vanessah4943 4 years ago AMAZING! Reply @PrankCallV1 2 years ago dang biology are machines we wish we could build 1 Reply 1 reply @advaitanahat2779 3 years ago Awesome! Reply @eddybobea6709 3 years ago Simplemente impresionante. Reply @Firstfruits288 2 years ago Peace I leave with you; my peace I give you. I do not give to you as the world gives. Do not let your hearts be troubled and do not be afraid. - John 14:27 Reply 1 reply @albythegreat4648 1 year ago It's like having tiny nuclear powerplants in your cells. Reply @kuldeepkcri 1 year ago Our entire lives basis explained in few minutes. Reply @ciafoxyloxy 2 years ago are mitochondria organelles ? Reply @quotidien_ 3 years ago How can free protons exist in both the matrix and the intercellular membrane? Wouldn't the protons bind to the water molecules to form H3O+? Reply @UMMAT1100 7 months ago A fully automated cellular power plant!!!. This cannot be of its own as they say all things come out of chance. This is not chance this is pure intelligence. Reply @neuronneuron3645 2 years ago How does the system detect a lack of a protein gradient Reply 1 reply @shahparwar272 1 year ago PERFECT Reply @preciouse 4 years ago the body is amazing Reply @HoaLe-py5ij 1 month ago Wow, philosophers were not wrong at all to propose biological nanoscopic machineries inside living bodies Reply @PotatoMcWhiskey 2 years ago Molecular Turbines bro wtf 1 Reply 1 reply @sahelanthropusbrensis 4 years ago I can learn any Science but, for some reason i have a terrible time trying to understand biology. I learn it today, i can't remember tomorrow. Reply @josecardenas8334 3 years ago 7:10 looks very similar to tree/fungal structures on Mother Earth, but just digitized and defragmented. Reply @nullskull 2 years ago Let me get this straight the mitochondria is the powerhouse of the cell ? Reply @ronaldpokatiloff5704 1 year ago A computer must make life!! Reply @ronp5615 3 years ago Did you license this from the Markovians? :-) Reply @colinwilloughby6790 3 years ago After watching these I expect to look into my eyes in the mirror and see a little creature with a steering wheel driving 'my' body 1 Reply @davipervenom9151 4 years ago It’s difficult to comprehend that all this complexity happened by mere chance. Reply @mosaddekahmed8550 2 years ago অনেক ভালো লাগল Reply @balajippasumpon3333 5 months ago Anyway mitochondria is a powerhouse of cell.😂😂 1 Reply @noaf2278 3 years ago is the first cell a plasmocyte ? Reply @bingpengyan2375 2 years ago It will be better if could have subtitles since my English listening isn’t not so good Reply @ayeshasiddiqha3250 6 months ago Hi there, I have taken biochemistry as my major (without researching about it). I don't know what to do next. Can anybody help me........ Know To what........scope ......and will be demand for jobs in future. Reply @pumpkinwizard9080 1 year ago So you are saying Mitochondria is not a completo? Reply @samuelthomasperkins 3 years ago For a popular science book that delves into the history and present (as of 2015) state of knowledge for cellular bioenergetics, check out The Vital Question by Nick Lane. Reply @AB-if8pd 2 years ago Knowing all these information and their relations to each other, has anyone even tried to make one mitochondria anywhere? Reply @accaboudesair 2 years ago Love it Reply @SecondShiftPleb 3 years ago What form does the proton come in? Is it a stand-alone proton (i.e., hydrogen without any electrons), or does it come in the form of any positively charged atom? (probably hydrogen) Reply 1 reply @hectorhugoariasvasquez8632 4 years ago Excelente. Reply @kiranbhardwaj9167 4 years ago Understood! Reply @kega4062 2 years ago so cool!!!! Reply @michaelrowland-us3he 4 months ago (edited) At 2.32 when he says protons are the same as hydrogen ions? Reply @heivmnox 4 years ago I would never look life the same way again.. i now respect my hardworking cells. lol Reply 1 reply @yuunishinoya439 3 years ago thank youu Reply @danielvillanuevaavalos 2 years ago Hello. Is there a way that I can get in contact with the creators of this animation? Thank you. Reply @gurammanjavidze6150 3 years ago (edited) i still didn't understand why don't all electrons go into intermembrane space and form water moleculs? Reply @marchelandersen6839 2 years ago i like this. oxygen turn intoo water can your body also split water if it can how does it do it ? i love this. Reply @rovatogger 4 years ago Amazing Reply @mohammadmokhlis8652 2 years ago سبحان الله الذي خلق كل شيء Reply @machina_aeterna 4 years ago Stardust turned into this...then into me typing this...and what would an intelligent race know after a million years? Reality is incredible, and I want nothing more than to understand it all, despite the impossibility of that happening. Reply @willoughby1888 1 year ago My favorite part is how not a single word was "white", "black", "brown" and I think you get my meaning so I'll stop mentioning races, I mean colors now. This video proves we're all the same on the inside more than we are different on the outside. Ok, I'm just a nobody 1970's 11th grade Highschool dropout with a GED who still likes to ponder things in order to keep my old man brain 'alive', so, I'm kinda wondering how much the 'more pervasive now' bacteria "Vibrio Vulnificus" would love to chomp away on all those pretty, colorful, hard-working organic items in this video. Complex I, II, III, IV could be dinner courses before all the many other desserts on the menu. Wouldn't be that complex a thing for a flesh-eating virus is what I'm thinking, even! Um, forgive me please, I was only trying to Bee Fun Knee. Maine said to say, "Hello" for it, except for one little bitty island, but I don't think they even have an email let alone mental telepathy like the rest us on the mainland just like to use. Reply @raplopez4258 3 years ago (edited) 7:10 The only thing he got wrong, and substantially wrong: Mitochondria is NOT a powerplant It IS a POWERHOUSE Reply @pavelshalnwv8494 1 month ago How great is the Lord! 1 Reply @hz6612 2 years ago Sobhana allah , allahou akbar 1 Reply @EarthGoddess369 4 years ago (edited) Awesome!! I'm particularly intrigued with the reason why we breathe .. I'm working on a book and it ties in exactly with my theory .. Many thanks 🙏🏽 Is that a slight Jamaican or other WI accent i detect in the Narrator' s voice.. ? Reply @ОльгаГейнц-м6к 1 year ago Nur Gott konnte diese wunderbare Welt in uns erschaffen!🙏🙏🙏 Reply @crenapun57 3 years ago Tq Reply @dominators7118 2 years ago Wowtastic👍💕 Reply @cuatropolis2881 4 years ago Life is simple, they said 1 Reply 1 reply @tacitozetticci9308 2 years ago How about anaerobic bacteria? Reply @ebigarella 4 months ago The crazy broccoli carnival Reply @musaritrashid2517 3 years ago Nice Reply @joseramonpradorickemberg7655 3 years ago (edited) Execelente la presentacion, podrian traducirla al español latino, somos subdesarrolados pero nos interesa la ciencia, de lo contrario no la suban al youtube. Reply @Cafecortao 4 years ago so niceeeeee Reply @outblufferoutbluffer2481 1 year ago Wait, I m fascinated by this but can't wrap my mind around it So if an atom is the size of a soccer field the proton is a grain of sand in the middle of the field , yet here in mitochondria i see electrons and protons working so close to each other..... Also I thought electrons are actually a cloud of probability.... I m confused Please make me ...... just bring light ! Thank you! Reply @JHilak 3 years ago its like micro-starwars! but what exactly happens when the redox centers in the proteincomplex send green circles and the protons are pumped? Reply @KM-fl5jq 3 years ago So, in the Complex 4 oxygen is converted to water not other way around?! Reply @anjanaybajaj3402 1 year ago if anyone is feeling down, just remember we indians are being taught this at 16 years of age have a nice day Reply @9d8fb79fd8gb 3 years ago RIP Rob Lue Reply @naikrosh 2 years ago Awesome Reply @MarkHopewell 2 years ago Unimaginable complexity marred only by one single fact: this complex and majestical process is still ongoing inside Donald Trump as we speak. Thank you for this animation and all the work that went into it, let alone the discovery of it! Reply @wyopoksfan 1 year ago a QR code in a Meow Wolf took me here Reply @anomalyp8584 3 years ago And then to think that this ATP generator spins like crazy. Not slow like in this animation. Reply @drezilla1310 3 years ago And people say this built itself by pure luck. WOW! God bless you all! Reply 1 reply @tk423b 4 months ago How do it know Reply @josue25 10 months ago Awesome🎉🎉🎉🎉 Reply @belginruzgar6130 2 years ago Nuray Akkaya Zonuz hocamız Türkçeye çevirdi. Ben buradaki videoya ekleyemedim. Reply @suraiyasuraiyajui5141 4 years ago Good Reply @brianadams5996 4 years ago When i was in school atp had just been discovered. I wonder if cells look different depending on the food we eat. Glyphosate or roundup is dangerous to humans. Reply 1 reply @snakesandsticks 2 years ago Where was this when I was an undergrad? 😩 Reply @dal2888859 3 years ago The level of sophisticated engineering and absolute precision required for this process to go on automatically trillions of times per second for an average of 70 some years boggles the mind. To assert that this entire network of nano machines somehow pulled itself together from inorganic matter has to be the height of willful ignorance and stupidity. 2 Reply 5 replies @marianas.1315 3 months ago girlllllllME ENCANTÓ Reply @shanrafnezden7958 3 years ago I fucking love science! Reply @idlehour 2 years ago (edited) so many inventions made by humans originally worked/are based on the concept of the many aspects of a cell's complexity. And we didn't know it at the time of inventions like turbines, fuel, movement and manipulation of electricity etc... are just stolen from evolution we couldn't see until recent times. 1 Reply @JJ-qd8ek 3 years ago (edited) I was like "what is this electron transport chain about", then I was like 🤯 Reply @anaghanair3387 3 years ago This made me feel ALIVE Reply @yinyang.333 4 years ago That's what India yogis has said billion years ago, and advocates Yoga, Pranayama to take deep breath because more amount of oxygen will make sure more ATP generated, more ATP generation nurture body energy store and makes body healthy. Reply @robinsonchukwu7295 2 years ago How do they know this... That's my question 1 Reply @زهراء-ر6ر2ش 5 months ago its very easy Reply @k_catboy 2 months ago This new Inside Out movie is weird fr 1 Reply @servetbozdag2359 3 years ago We just find it out. Very well. Who did this amazing coplexity. My imagine is that comes from one and only Allah( Celle Celaluh). Appreciate for explanation Reply @mlauntube 2 years ago God's design for life is so amazing. I just don't see how anyone could believe that life came from rocks; that is just so silly. 1 Reply @maxjurish2589 2 months ago This is a good time to start believing in the genius God the creator and putting evolution in the trash can! 1 Reply @yame8134 4 years ago モーターの回転数は負荷が軽ければ1分間に10000回 電ノコは1分間で1400回転とか。やべぇよ Reply @espy0008 3 years ago Wow, the fact so many people believe this complex system, only being an extremely small part of larger organisms, happened by chance and that all living organisms began as a single cell is proof of the smarter people get the dumber they are. Reply @Stas_bool_bool 2 years ago Ради одних этих видео хочется английский изучить... Reply @Geekyavi1 2 years ago 2 times the data showed in this video is in MY class 12 Biology Book in India in only 1 page. Reply @VectorOfKnowledge 2 years ago Given all the complexity of biology, I can see why some people would be too lazy to learn about it properly and would just be like, "Ah, fuck it. God made it." Reply @subhashranjan3722 3 years ago Awesome Reply @shadymcnasty5920 2 years ago The fact this occurred naturally without design is absolutely mind boggling Reply 2 replies @Vibycko 2 years ago So you are telling me, that mitochondria have a firetrucking turbine to create atp!? 1 Reply @Derpy1969 1 year ago I see Pinkie Pie, Twilight, Rainbow Dash, Applejack, and Granny Smith. Reply @PookieAndAnnie 1 month ago This was posted 6 years ago😮 Reply @nggmodding7111 8 months ago nice Reply @ricardodm4999 1 year ago Que alguien lo traduzca, ¡por favor! Reply @JBulsa 7 months ago Proven to be incorrect. Electrons bond differently along the transference. Reply @Sweta_thakur711 4 years ago Every molecule is an universe in itself...... Reply @aysgl2666 1 year ago i don t understand how the energy required to pump protons are collected from the flow of electrons- those green circular clouds in the complex 1 4:53 Reply 2 replies @Dude_Its_Michael 1 year ago at 1:00 it says the intermembrane space has more protons than the matrix but shouldn't that be the other way around, Don't they move from the maxtrix into the space. Reply 1 reply @alexciocca4451 1 year ago We are the best machines yes gotta loveit Reply @kevinharte3636 9 months ago How the hell did people figure out this stuff?!?!?!?!?!?!?!?! 1 Reply 2 replies @HussainMushtaq0 10 months ago (ربنا ما خلقتَ هذا باطلًا سبحانك) 2 Reply @collinarter2470 2 years ago NGL I thought this was a Worms Armageddon map at first. Reply @robson6213 3 years ago it makes me wonder if life is just a coincidence 1 Reply @ultrad-rex1389 3 years ago Life is so complex, it's fragile... Reply @soamazing7027 2 years ago Great Video! (Jesimiel Millar Fernåndez) 1M937 Reply @ilkerongun3962 4 years ago Travelling protons idea is only an approach - what really happens is the travel of an electron in the opposite direction. Reply @samirsha6762 2 years ago God is the greatest 🙌...wonderful creation 1 Reply 2 replies @vaishuupare099 1 month ago 3:30 : wow Reply @สมชายอิ่มโพธิ์-ท6ช 2 years ago ขอบคุณ Reply @radwizard 2 years ago Wow, a current. Reply @MostlyPennyCat 4 months ago How come those protons, hydrogen nuclei desperate for an electron, don't tear everything around them apart? I would have thought all that charged atomic hydrogen would rip electrons of anything it got near. Reply @bestelectronicmusicfromnew5189 3 years ago that's why i prefer astrophysics and black holes. a lot easier. and... if i understood this right, we are made of psychadelic muticolor bogies? Reply @mikemurawski8112 3 months ago A QR code at Meow Wolf brought me here Reply @jan_phd 3 years ago When you say GIANT cellular powerplant... what is the scale of that? Reply @devdalwadi31 3 years ago I still do not understand why we learnt photosynthesis before cellular respiration Reply @ترميمالحياة 3 years ago الا يوجد ترجمة؟ Reply @mjproebstle 3 years ago this is insane in the membrane! Reply @jeendabhagat1670 2 years ago exterimely excullent Reply @zynius 2 years ago In 2030 we'll simulate this on an atomic level. Reply @megangeorge437 1 year ago Meow Wolf Denver sent me here Reply @mercster 2 years ago (edited) It amazes me that there are those who think the idea of a creator is laughable. 1 Reply 12 replies @maxjurish2589 1 year ago If scientists can't see a creative God in this magnificent structure and function then God help them! Reply @hectorhugoariasvasquez8632 4 years ago Por favor podrían activar los subtítulos en español ? Reply @gtbproductions1 3 years ago How can anyone say we evolved from nothing that happened to appear in the ocean. We have a great creator, God. Do you really think this all happened by accident??? 1 Reply 2 replies @thebest9791 2 years ago Where the duty of heme iron here? Reply @Safar_Galimzyanov 4 years ago At first I thought this was SovietWomble`s video Reply @Sara-md8nu 2 years ago Having taken 4 biology classes in the last 2 years, I literally forgot everything and cellular respiration... hah! I'll never understand that Reply @nancychandler768 1 year ago And yet, my general practitioner says this is not part of her repertoire. Reply @MuhammadSaeed-ym5qr 1 year ago Great Reply @zafran156 2 years ago ok! Reply @DunateoRom8v37 3 years ago Please explain this from a Darwinian evolution perspective. Go on, I'll wait. Or Explain this taking in to consideration irreducible complexity to illustrate pure naturalistic processes. Go on, I'll wait. 1 Reply 1 reply @SmileyIsAlone 1 year ago You know it’s Harvard, when you don’t know what’s going on! Reply @user-sy5jb3gj2p 11 months ago Wow, that darwin guy who called it a "simple" cell didnt know what he was talking about did he? Reply @sayedelghairb8640 3 years ago Glory be to Allah 🙏🤲🏻❤️❤️❤️❤️❤️❤️❤️ Creator of everything 1 Reply @jacoblikestodab 4 months ago I’m at meow wolf and there was a url on the wall I’m on acid and this is what popped up Reply @AClarke2007 3 years ago And the whole Plant and Animal species living in a thin membrane on the surface of a Planet too. Reply @widescreen8964 2 years ago Where do these protons come from? Reply 1 reply @dimitriosdesmos4699 3 years ago I used to be good at this !!!! Reply @stockmarket2041 2 months ago Hard to believe 😮 Reply @JosiahFickinger 2 years ago It takes blind faith to believe these complex systems of complex systems of complex systems evolved with a blind purpose and without the intelligence of a creator God. Thanks for this fascinating and informational video! Reply 1 reply @flewggle 3 years ago Why would anything like this occur naturally??? Reply @dma67111 4 years ago And Pac-Man 1 runs to center 1 and 2. Ghosts 1&3 ...etc etc Pacman goes to center 4 and you win Reply @XavierAway 3 years ago Maybe if we could synthesise this system we can create electricity with the best possible efficiency Reply @golammahdi1077 2 years ago Transcendental Reply @rokus100 3 years ago If you are not amazed, humbled by this stuff you just didn't get it Reply @tomoakhill8825 4 years ago At 6:50 "the reason we breath oxygen is so it can be the final acceptor of Reply @genius6225 2 years ago But why does it produce water in the end, we drink water all day. Reply @vladtherussian9594 1 year ago How in the world did you manage to know that the last Redox center in complex 1 donates exactly 2 electrons to the coenzyme Q molecule? We can barely see DNA under the microscope let alone subatomic particles. Mathematics? Reply 2 replies @marchelandersen6839 5 months ago electric universe electric beings Reply @KanesMeridian 1 year ago Shoutout you if you got here thru the denver meow Wolf Reply @Azavar_Kul 2 years ago Чудо и обыденность в одном флаконе ) Reply @Sickwitit18 2 years ago Meow Wolf Denver has a wall of QR codes and one brought me here Reply @zbigniew2628 3 years ago How it happend to be this way? How just from dust of start this design happend? Just trial and error method over milion of years? Reply @EntityAiden 7 months ago Got this video from meow wolf 1 Reply 1 reply @bertwesler1181 3 years ago You do realize that when he said, "Have great affinity" that he has no idea why or what that actually means. Reply @kanviaery2542 3 years ago Matrix has less no. Of protons then how these complexes can pump protons from matrix to inner membrane , shouldn't it be opposite? From membrane to matrix?? Reply 1 reply @qawiyya 2 months ago thanks MeowWolf Reply @Дэни-д6ю 3 years ago rip Prof. Lue Reply @yosra4365 1 year ago سبحان الله العظيم Reply @gangadharr3524 2 years ago First, wanted to know how they figured this out...? Reply @stevenwiederholt7000 4 years ago Remember now, all this came about random chance. Riiiight! 1 Reply 5 replies @VoidHalo 4 months ago How can protons exist individually within the intermembrane space (or anywhere) if it's impossible to have solvated protons. Ie free protons in solution which are not bound to any other moiety. Something is being omitted here. Reply @edelweisslandscape 4 years ago we are trying modifying something that we didn't know, coz we are not the creator. Reply @miketrissel5494 1 year ago ... and yet there are still some watching these amazing and miraculous little engines, thinking that all of these micro processes evolved separately, yet at the same time, to become the building blocks of life...... Romans 1:21 "...they became empty-headed in their reasoning and their senseless hearts became darkened. Although claiming they were wise, they became foolish and turned the glory of the incorruptible God into"...... Reply @drdeiceekay6865 2 years ago I have more questions POST watching, than pre... 😅😅 Reply @krose2913 2 years ago Came here from Meow Wolf Denver Reply @spookyaction 1 year ago this is a very high technology. Much higher than humans currently developed. We dont know the origin of this technology. Reply @hashrafi7148 4 years ago does anyone know how to make a biological animation like this? Reply @martahernandez6034 3 years ago interesting Reply @LifeOnMarzMI 4 months ago Anyone here from Meow Wolf in Denver? Reply @ghaznawi143 1 year ago loved (💜) Reply @harishchad. 1 year ago matrix ============8=9==6==3==== intermembrane space Reply @dungeonkeeper42 2 months ago I don't get it Reply @fatihcihancelebi4613 4 years ago Why we have to breathe for oxygen can't we reuse it? Reply 1 reply @shadow_-.- 1 year ago Who got this from meow wolf 👇 1 Reply @ivanbombana7282 4 years ago (edited) How the biologists understood all of this? I don't understand... Reply @PsychicLauryn 3 years ago Meow Wolf Denver anyone? Reply @Voiceofmine12 1 year ago That's fi and fo partical not f0 Reply @mohamedalshaikh145 9 months ago حسام عياش Reply @universalflamethrower6342 3 years ago that is abiogenesis for ya, stuff emerging from stuff Reply @yns7430 2 years ago When we able to make artificial mitochondria Reply @gustavolamounier1224 3 years ago Poderia ter alguma legenda Reply @testsubject318no6 5 months ago Aren't the protons in the Na atoms... or sth... Reply @markmd9 3 years ago Does this look like designed or like an accidental evolution? 1 Reply 11 replies @ajb408 3 years ago Meow Wolf took me here Reply @laxmibhandey-oi3cl 1 year ago Can be it in hindi Reply @SubhranshuSahu07 1 year ago (edited) I think Biochemistry all about concept and understanding unless you make out it it is too complicated..🤦 1 Reply @johaniswara5086 4 years ago future study major might be "Cellular engineering" Reply @yaseralz3bi407 2 years ago سبحان الخالق Reply @mnyhomie 2 years ago Denver meow Wolf 1 Reply @katherinelanoue8173 1 year ago Reply if you found this video through MeowWolf Dever, CO Reply @NguyenNgocKhue-x8z 1 year ago Không liên quan nhưng tôi muốn kể cho các bạn nghe một câu truyện: Tôi vô tình chụp ảnh đám cưới của người lạ. Bây giờ, họ gửi cho tôi một thư cảm ơn vì đã làm cho họ có một bức ảnh đám cưới tuyệt vời, mặc dù tôi không biết ai trong đám cưới đó. Reply @kxmode 2 years ago "O Jehovah, . . . I praise you because in an awe-inspiring way I am wonderfully made." (Psalms 139:1, 14) 🙂 2 Reply @shefochi5566 2 years ago There is no way this is made by evolution. 1 Reply @jasonmay4341 2 years ago rip rob Reply @markmanning2921 3 years ago but you will never admit that this was CREATED by the creator but instead insist that all this was caused by a random event in some pre-historic puddle of mud where said puddle of mud jumped up and said "Im Alive!" 1 Reply 2 replies @tracycampbell9300 2 years ago Wow. Reply @chetanpaulr 2 years ago My God 🙏 Reply @pecador_tor 4 years ago evolution sure does go a long way huh :O Reply @aveb1041 1 year ago Did anybody else get sent here from Meow Wolf lmao? Reply @RainAngel111 2 weeks ago When I started to learn biochemistry, I realized how messy and well, inefficient it seemed, especially compared to artificial electronics. And it is! It's just that powering a big sack of meat without wires or strong magnets requires this kind of delicate mess. How else could it be done. It's funny that biochemistry feels like evidence for and against an intelligent creator. It's so complex it seems impossible it could arise by chance, yet so inefficient and seemingly sloppy that it seems crazy to say an all knowing god created it Reply @abirhasan8731 2 years ago My God! isn't it beautiful... Reply @gnomologist 4 years ago Would have been better to talk of hydronium ions rather than protons... Reply @meeraghodajkar3830 2 years ago (edited) No need to memorize ETC afterwards watching these animation video Reply @ninjamatic5000 3 years ago how the hell did people find out about this? Reply @8starsAND 3 years ago I'm here at 4.51 am... Reply @gegeeneemns5209 2 years ago ok Reply @unknowngozi6386 3 years ago So complicated Reply @yogeshchaudhary5821 1 year ago Best best best Reply @ughugh3556 2 years ago How the hell does something like this "evolve"? 2 Reply 7 replies @dabidmydarling5398 2 years ago Who is here from ap bio? Reply @ehhhe 2 years ago Meow wolf sent me here Reply @holdensilvey 1 year ago Who's here because of Meow Wolf? Reply @colelarson1201 2 years ago Meow wolf sent me here Reply @EMMANUELKOLAWOLE-p2s 1 year ago Thank a lot Dr pius oziegbe I will keep letting the world know about your good work and about YouTube channel ☘️ your herbal medication cured my HIV HSD AIDS completely am grateful doctor❤❤❤ Reply @rufus4779 1 month ago Evidence of GOD. All of this could NEVER have been initiated by accident. Reply @graynephalim 3 years ago How the hell did this end up on my feed?! Reply 1 reply @viraatsgaming5369 1 month ago Wow... Reply @jacobogutierrezsanchez 1 year ago For me, this is support for the existence of an Intelligent Designer. Reply @javiergarnik369 2 years ago All universitiees nerd that Reply @edsonborba5299 2 years ago Infelizmente não consegui entender não sei falar inglês é uma pena Reply @Passco666 3 years ago Now my body is smarter and will produce more Mitochondria :) Reply @локилоки-е7у 1 year ago МАША ефимова ис самары я тебя люблюeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shape Reply @benitocarmelo4296 3 years ago tuve un profe de biologia que le dijo a un amigo mio que si seguia encorvandose terminaria con forma de fosfolipido. ahora cada vez que veo algo relacionado con membranas celulares pienso en el xd Reply @pranavpatil6988 4 years ago My textbook didnt tell me this Reply @juansantana6307 2 years ago How do we figured this shit out in the first place tho Reply @РамильТатарин-о7з 3 years ago 5 Reply @aesius1847 9 months ago It's hilarious to me how someone can watch this and think these systems created themselves 😂 Reply @CDClock 3 years ago is that jules pierre mao Reply @bryanagarcia4973 1 year ago How many got here because of meow wolf? Reply @benlee5039 3 years ago So basically: its magic Reply @aliietzal3687 2 years ago سبحان الله Reply @astralmaster1692 2 years ago And some people believe life is "An Accident" 1 Reply 17 replies @koryschroeder2924 2 years ago Did meow wolf bring anyone else here? Reply @jacekpiterow900 3 years ago Hydrogen protons? Reply @BongoKotha 3 years ago Hey a lot of views u get from our C3 mentors , and you're watchtime will increase , show some respect to C3 mentors students 🙂 Reply @vinodunnithan1360 4 years ago Hi Reply @outrooutro8328 3 years ago why did scientists decided to figure out how respiration works in the first place?? Reply 1 reply @slehar 3 years ago Wow!!!!!! Reply @imnotridaaa 2 years ago Woahhhhhh! Reply @practicalengineering6965 1 year ago God is awesome Reply @zdravkomitev9349 1 year ago Fo not F0 Reply @valerierascon8528 2 years ago Meow wolf did this 😢 Reply @adairjanney7109 1 year ago I can believe in God forming by accident as an energy being before believing all of this happened by cosmic accident Reply @jele38 4 years ago What I learned from this is that our way of making atoms into others is a waste of energy and atoms are simply Legos looking for the right pice to snap to and we simply need to put them near eachother for it to happen and the energy given off by this reaction can be harnessed in cold fusion the same way our cells use it to praduce it into potential usable energy. 1 Reply @Harve955 1 year ago Hmm, sugar metabolism creating NADH. What about the alternative A Fat metabolism? Lets pretend for the sake of the Mega food conglomerates that sugar is the only metabolism contributing electrons for ATP synthase, after all our funding is almost completely dependent on the Food conglomerates. Reply 2 replies @girlandchocolate2012 2 months ago Meow wolf brought me here Reply @ghostaka7405 2 years ago woaah💯 Reply @mhdrn4484 2 years ago this is plan of God , we are the stream of electrons . a dance of energy Reply @raylol460 9 months ago ap bio students wya Reply @User24427 5 months ago (edited) Any NEET asperent? Here 2 Reply 2 replies @ketssa 4 years ago God is great Reply @mrfin1x113 2 years ago cool i actually understand some shit now before it was like not cool Reply @neuroboy2914 1 year ago I'm making medicine videos with memes, so you won't get bored here bro :) Reply @mudasirhussain3168 5 months ago How the f people find this much information.... Maths student here 🖐 Reply @markmd9 4 years ago It showed how oxygen is used to produce water but from what I know we breathe in oxygen and breathe out CO2. Where's the part that shows how CO2 is produced? Reply 1 reply @melikesehirli6042 4 months ago Nice visuals but a ton of important details missed, video becomes actually useless. Reply @allenharper2928 1 year ago Aww, he didn't say the thing!😰 Reply @memyselfandi.5822 4 years ago NANOMACHINE Reply @bluegrassreb1 3 years ago and this wasnt designed? Reply @paracletus3166 3 years ago Glorified be God Reply @davidrobinson6861 1 year ago Meow wolf brought me here Reply @samuelkahunga5987 3 years ago (edited) 0:08 Pikachu 1 Reply @spacewater5866 4 years ago How come they don't show ACTUAL mitochondria as it looks in real life. I dislike these computer graphics. Show us real stuff under microscope. Reply @Istanislav1 3 years ago мне это сносит голову Reply @QbutNotTheQ 1 year ago This is how you burn a muffin. 😊 Reply @jimschiltz5343 2 years ago My God! Reply @elviscaragea4433 11 months ago Like a machine Reply @МатвейДанатов 2 years ago мудрость Reply @StrawberryBunny91 3 months ago Anyone els scan this one at meow wolf? Reply @abbigailhoffman1748 1 year ago anyone else here from meow wolf? Reply @lynne1609 7 months ago Phenomenal. No intelligent planning in the creation of this system, hm? Reply @Vmartin70EZ 3 years ago Electrons are used to power those microscopic pumps 😳just like electron flow is used in todays electric motor powered pumps! Reply @zzz181085 2 years ago Meow Wolf link anyone? Reply @yolanda6392 2 years ago bruh no one told me that enzymes were this BUTT ugly Reply @Blankii69 2 years ago Ratio Reply @aalokshah6207 1 year ago why can't we take other gases of oxygen family to accept our proton ... for like if we did use sulphur we would be releasing H2S and that very good for anaerobic bacteria(specifiaclly sulphur bacteria) and..............if that was true on earth there would be a cycle between bacteria and us animals without having plants may be.... on the whole planet Reply @JosiahFickinger 2 years ago "The fool has said in his heart; There is no God" Even though no matter the complexity, people will still yet say it evolved. It's foolish to say that complex systems of complex systems of complex systems all evolved blindly apart from the intelligence of God. Reply 4 replies @diptirajput7881 4 years ago Wao Reply @ashoksavlaramchoudhary3180 1 year ago istudy this in11std respiration in plant Reply @Dr.AhmadAlsyouri 2 years ago then a blind man says where is the creator I can not see !! 1 Reply 1 reply @JoshButterballs 2 years ago FYI This and similar research is commissioned as a means to understand the many ways to destroy the human body en masse. Reply @IIrandhandleII 4 years ago Huh? Reply @mobiustrip1400 1 year ago Reality is just a show. It's a matrix. It's a video 🤣 Reply @DuumaZ 4 years ago "Just as man made powerplants" yep just wait a couple of billion yrs and this kind of machine will just pop out on it's own. Not to mention the whole cell itself... there must be a creator. 1 Reply @Daubix 1 year ago Meowwolf gang 👇 Reply @สมชายอิ่มโพธิ์-ท6ช 2 years ago และครับการโต้แย้งอาจมีบ้างแต่ทำด้วยความเครพและเพื่อให้ผู้จัดทำได้วิเคราะห์ก็เพื่อให้ได้ความจริงและน้อมร้บกับคำอธิบายพร้อมขอบคุณการนำเสนอครับ Reply @Asdayasman 3 years ago Abdolutely insane how all this shit is just randomly generated. 1 Reply 6 replies @boughrietmohamed9411 3 years ago (edited) 🎨🖌️☝️🧠💯 Allah Allah 1 Reply @lauram9478 1 year ago ❤ Reply @MikkloGames 1 year ago Uhh I came from meow wolf and I am not qualified for this 😵‍💫 Reply @its8484 3 years ago ❤ Reply @MaskedMarble 2 years ago Truly God’s design of life is amazing. If one of these pieces were functionally missing, life wouldn’t be alive. Thanks to God that he had the foresight to put this all in place from the inception of life’s creation. 1 Reply 1 reply @imagination3815 2 years ago Ah yes 5Head Reply @eselseptimo 1 month ago La vida Reply @hdhddhdb2894 2 years ago فى حاقه Reply @swally1206 3 years ago الله أكبر. Reply @meghdaniellama1604 2 years ago What Reply @kokochanukrit9989 2 years ago This reminds me of a turbine Reply @ObscureAudioHistory 1 month ago Wat Reply @수하긴 4 years ago More oxygen please Reply @juliannak2771 2 years ago 💙 Reply @emil.jansson 4 years ago 🤟🏻 1 Reply @josse4949 3 years ago no se como llegue aquí, pero encontré diamantes ^^ Reply @leom091 3 years ago Videardo! Reply @alexanderpushkin9160 4 years ago Insane. Reply @TylerSmith-is8im 2 months ago Like if Meow Wolf brought you here Reply @majidrahmani204 1 year ago 👍👍👍 Reply @xwsftassell 3 years ago Why you should smoke cigarettes. Reply @ausumncf9754 3 years ago Complex 2 looks like a fried chicken leg 🍗 Reply @Firstfruits288 2 years ago Be still and know that I am God; I will be exalted among the nations, I will be exalted in the earth. - Psalm 46:10 Reply @thochan5188 3 years ago Is my is my mother goose club out. Reply @evanrutherfordlazyahole9079 1 year ago Im not an android leave me alone. Reply @สมชายอิ่มโพธิ์-ท6ช 2 years ago ตามหลักการของการชนต้องมีแรงจากการกระทำต่อวัตถุกับวัตถุครับ Reply @dunk_the_munk2174 6 months ago Who here from meow wolf ? Reply 1 reply @nvppatilmyhistory6733 4 years ago Electron transport system s proton of covid 19 working which chemical compound covid 19 destroy Reply @333Paradigm333 2 years ago I find it revealing that the narrator @ 1:28 compares the ATP complex to an man made power plant, and whereby he unwittingly invokes the principal of intelligent design. The impossible complexity of a "simple cell" cannot come to being by "chance & time". There is the appearance of design because it has been designed by God himself. Jesus is God incarnate in the flesh, he died on the cross as a substitute for the sins of the world (yours & mine). "For God so loved the world, that he gave his only begotten Son, that whosoever believeth in him should not perish, but have everlasting life. For God sent not his Son into the world to condemn the world; but that the world through him might be saved. He that believeth on him is not condemned: but he that believeth not is condemned already, because he hath not believed in the name of the only begotten Son of God. And this is the condemnation, that light is come into the world, and men loved darkness rather than light, because their deeds were evil." John 3:16-18 Reply @slee9838 3 years ago Waoww Reply @Vmartin70EZ 1 year ago These Microbiological Machines and their complex working System cannot be other than the result of Intelligent Design. Reply @funny3511 4 years ago My body is a huge power plant... ME: Dota and Pornhub Reply @carmendamic77 3 years ago .doppiato ...in italiano...no? Reply @jec1987youtube 2 years ago Clearly this was not intelligently designed and happened by chance coupled with random mutation. Reply @পাঁচমিশালি-দ৭র 2 years ago 🤩🤩 Reply @eddienekitiah 1 year ago The biggest proof of God's existence 2 Reply @Haveuseenmyjetpack 4 months ago Hard to believe random mutations and environmental pressures resulted in THIS! 1 Reply 1 reply @Potatomatoo 3 years ago Dammmm Reply @codyhaas1008 4 months ago So.. solve the creation, edit into dna 🧬, and generate immortal children would be possible 🎉😮😮😮 Reply 1 reply @laviniaminotti4548 2 years ago 😍😍😍😍 Reply @ivin6415 2 years ago Repent and believe the gospel of Jesus Christ 1 Reply @ajmalabidin1307 1 year ago SubhanAllahil Azizul Hakeem Reply @ayushtanwar6074 5 months ago Neet aspirants 1 Reply @damaster7276 4 years ago Now reverse the process and we can drink water and produce Oxygen Biokemist Reply 1 reply @amszulu 9 months ago lol Meow Wolf Denver brought me here Reply @hdhddhdb2894 3 years ago د. Reply @akbarshoed 1 year ago No God. Stop thinking about God, please. Reply @Firstfruits288 2 years ago The Lord make his face shine upon you and be gracious to you; the Lord turn his face toward you and give you peace. - Numbers 6:25-26 Reply @santiagos4290 2 years ago epic Reply @boughrietmohamed9411 3 years ago Allah Allah tout puissant Reply @MrGoat-kz1mf 3 years ago 19BOT036 Reply @blainefiasco8225 3 years ago Those membrane tails look like they tickle. Reply @marinaquintinosilva. 3 years ago 💚❤💚❤💚 Reply @atharvamathapati8259 3 years ago 👍🏻👍🏻👍🏻❤️❤️❤️❤️🔥🔥🔥🔥🔥 Reply @fadlulaiabdu-raheem4612 1 year ago And they said there is no God. 1 Reply @skymaster0yt 2 years ago whaat Reply @munzak27 3 years ago OMG, why do I just see it now and understand now :( Reply @hasim2818 2 years ago Kacaeli tıp Reply @islam333 3 years ago Жаль не на русском но я все и так понял. 😉 1 Reply @bryangoldfield3861 3 years ago The melted lettuce preliminarily number because ray cytopathologically advise until a thundering ptarmigan. meek, young design Reply @corbalord 1 year ago Complex 3 looks like fried chicken lol Reply @theunique880 2 years ago 🌈😍 Reply @oluwanifemikim1996 1 year ago Now tell me God isn't wonderful 😌❤️ Reply @user-um3yp7dl1n 11 months ago thats the creation of god 1 Reply @IbrahimJawabreh-gk5dr 1 year ago سبحان الله Reply @imovertheocean 3 years ago but are the complexes republican or democrat? That's the burning question, surely Reply @geocacheguy6736 1 year ago This video proves there is no God lol Reply @thoughtthinker9300 1 year ago All of this, no matter how complex, comes down to the very same BEGINNING QUESTION. If in deed we are too complex to be created by random chance happenings, and we were purposely created by design. HOW was the first being or whatever in this chain of life and creators created? BUT BY THE SAME CHANCE OF RANDOM HAPPENINGS, THAT ARE SAID IT'S IMPOSSIBLE TO DO. Or in short. Who and How was the first "????" that was created, CREATED? Or is that us? Or where and who or what "was it" ? This is and may always be the ultimate "BEGINNING QUESTION". ENJOY Reply @cctransfer17283 1 year ago (edited) This is a joke. Felt like I was in the Mcdonald's ball pit/ car wash the entire video. Back in my days at Harvard, this poor level of editing would never fly. Action will be taken. Happy Halloween. 1 Reply @skyward7699 3 years ago GLORY TO THE LORD Reply @samphel4478 1 year ago 0/10 not recommend Reply @satendralodhi5552 4 years ago Please Hindi Mai samghaiye Reply @montanawildhack2760 1 year ago holy fuck Reply @ryanramkalawan8441 8 months ago Im here from meow wolf Reply @Firstfruits288 2 years ago Lord Jesus Christ peace is an inner treasure, growing within you as you trust in me. Therefore, circumstances cannot touch it. Be still, enjoying peace in my presence. - Alyssa Bomber Reply @codrut913 2 years ago <3 ! Reply @madrugade8242 1 year ago Ok, so who can tell me with a straight face that all this just evolved by itself, through a purely random, undirected, creator-less process? Reply @Firstfruits288 2 years ago Take time to be still in Lord Jesus Christ's presence. - Hannah Bomber Reply @χρηστοςΜπακολουκας 3 years ago !! Reply @thaq8.2 1 year ago Qhaq Reply @babacut7561 4 years ago moin Reply @saysHotdogs 1 year ago biology is just fat chemistry change my mind Reply @marshalljordan2416 1 year ago The electron transport process could not evolve by random mutations and natural selection. Therefore God must exist. “For the wrath of God is revealed from heaven against all ungodliness and unrighteousness of men who suppress the truth in unrighteousness, because that which is known about God is evident within them; for God made it evident to them. For since the creation of the world His invisible attributes, His eternal power and divine nature, have been clearly seen, being understood through what has been made, so that they are without excuse.” Romans 1:18-20. Reply @vickiecastro433 2 years ago Please do not add your convoluted personal comparison. Facts only Reply @philipb2134 4 months ago This is a high-grade explanation. Lower margins of comprehension might better fulfill the didactic purpose.bleh Reply @nickkrug8157 3 years ago God is great !!!!! Do you truly and really think that this belligerent amount of complication evolved in some "POND" somewhere a million years ago...!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!! 1 Reply 2 replies @jiangxu3895 4 years ago This is fuel cell made by God. Reply @oleoelamparina53 1 year ago That's why I beleave in Jesus. His wisdon created this and much more we yet don't know. Reply @francoisfaure9089 2 years ago 😂😂😂 Reply @iloveSUVs 7 months ago Do you really believe this happened by chance? Reply @kaiseraugustus1393 3 years ago (edited) And btw, of course, all this happened by chance... for sure... :D Darwin was dead wrong.... 1 Reply @Gerdaldfighterkid 4 years ago that cant just be a naturally occurring accident, how could evolution had given it the direction to accomplish these goals 1 Reply 1 reply @barnarus 2 years ago And who designed this????????????????????????? You know the answer........ 1 Reply 3 replies @dwaynerobinson6494 1 year ago Thank you Yahweh Reply @sumhump1075 2 years ago wack Reply @Amrelmasrii 1 year ago (edited) wow ! Look how great the creation of Allah is, I really pity the disbelievers and atheists, use your mind and open your heart bro! Allah Subhanahu Wa Ta'ala said: "Do they not contemplate within themselves? Allah has not created the heavens and the earth and what is between them except in truth and for a specified term. And indeed, many of the people, in [the matter of] the meeting with their Lord, are disbelievers." (QS. Ar-Room 30: Verse 8) Reply @gavincurtis 1 year ago iT's a MiRaCLe oF eVOluTIOn. Reply @ErikS- 4 years ago And Darwin thinks this is something that randomly evolves in nature... I dont believe it. This complex of proteins looks very engineered. 1 Reply 1 reply @grantfryer407 3 years ago and you still think all this came about by chance (THEORY) of evolution 🤣 Reply @82ndAirbornesoldierofchrist 1 year ago And just think, this was all because of chance with enough time, with no intelligent design. Not a chance. Reply @kanayanfantv 3 years ago (edited) Saying that this came from evolution in an INSULT to intelligence. 1 Reply 14 replies @3zan6bel9 3 years ago Racist Mitochondria, making a difference between protons and electrons. Not very inclusive Reply @Rob8729 4 years ago Random evolution....yeah sure. Reply @marinator4988 1 year ago inaccurate Reply @theHentySkeptic 2 years ago Everything you see here is the accidental accumulation of tiny bits of it over time... hmm? Reply 1 reply @Kazmir 3 years ago This is a joke, right? Reply @chynnadoll3277 4 years ago (edited) And all this happened by chance, over billions of years, from a single organism accidentally formed.........YEAH, RIGHT😏....I DON’T THINK SO... How great Thou art, Heavenly Father❤️❤️🙏! John 1:3 (KJV): “All things were made by him; and without him was not any thing made that was made.” Reply 2 replies @ardeleanion4435 3 years ago BS Reply @salmonkill7 1 year ago I can really see the ATHEISTIC ARGUMENT for how life just began by blind accidental chance! The simplicity of this process is really what sold me on ATHEISTIC ABIOGENENESIS.... NOT!! Reply @lukehelpmetakethisdangmaskoff 2 years ago Chance mutations eh? The crap we believe... 1 Reply 11 replies @snapper1627 2 years ago funny how this all came about without intelligent design... Reply 9 replies @kendod1637 2 years ago God made. Reply 2 replies @hello-fw1pd 1 year ago Do atheists really think that all of this happened by accident? 1 Reply @grawss 2 months ago Read the Gospel! Start with John. You become saved by confessing Jesus as your savior; that he died for your sins and was resurrected from the dead. I highly encourage you to fill the emptiness in your hearts with the love of your Creator. Reply Transcript Search in video 0:05 RL: All eukaryotic cells, from yeast to those that make up the human body, 0:09 contain membrane-bound organelles with specialized functions. 0:13 Mitochondria are double-membraned organelles 0:16 that harness most of the energy that cells need to grow and reproduce. 0:23 Nearly all of this energy comes from reactions that take place 0:27 at the inner mitochondrial membrane. 0:47 One of the key roles of this membrane is to act 0:50 as a barrier to positively charged particles 0:53 called protons, thus allowing a concentration 0:56 gradient to be maintained where the intermembrane space has 1:00 far more protons than the matrix. 1:09 The membrane also contains a large protein complex called the F1F0 ATP 1:14 synthase, which uses the proton gradient to drive 1:18 the synthesis of ATP molecules. 1:23 These ATP molecules ultimately provide the energy 1:26 for most of the cell's reactions. 1:29 Just as man-made power plants produce electrical energy 1:33 by using the flow of wind, water, or steam to rotate a turbine, 1:38 the synthase makes ATP by using proton flow 1:42 from one side of the inner membrane to the other to rotate protein subunits. 1:48 If there is no proton gradient, synthase subunits stop rotating, 1:53 and the cell can quickly become starved of the energy and die. 2:04 Therefore, the protein complexes and small molecules 2:07 that establish this gradient and maintain it 2:10 play an essential role in the life of the cell. 2:15 At the heart of this system are four protein complexes 2:18 numbered I through IV. 2:24 Complexes I, III, and IV directly pump protons 2:28 from the matrix into the intermembrane space. 2:36 Complex II does not directly pump protons, 2:39 but it does promote proton pumping in complexes III and IV. 2:50 Proton pumping requires energy, and the four protein complexes 2:55 get this energy by transferring electrons 2:58 through a series of coupled reactions. 3:05 This linked process of electron transport 3:07 is why the four complexes are collectively referred 3:10 to as the electron transport chain. 3:17 Let's focus on complex I. A byproduct of sugar metabolism 3:25 called NADH deposits two high-energy electrons 3:29 in complex I, where they are passed along a chain of redox centers. 3:38 Redox centers are clusters of atoms that have 3:41 different affinities for electrons based on their unique atomic configurations. 3:48 Let's closely consider a pair of redox centers 3:50 to reveal two reasons why an electron moves from the top redox center 3:55 to the bottom. 3:57 First, the bottom redox center has higher affinity than the top one. 4:04 Second, the distance between these adjacent redox centers 4:08 is ideal for an electron jump to occur, which explains why electrons typically 4:12 don't bypass the bottom redox center. 4:26 A small amount of energy is released each time 4:29 an electron is passed between redox centers. 4:33 Complex I harnesses this energy across all the redox centers 4:37 and uses it to pump protons. 5:02 The last redox center in complex I donates two electrons 5:05 to a coenzyme Q molecule. 5:14 Complex II is similar to complex I in two important ways. 5:19 First, high-energy electrons also enter complex II 5:23 via a byproduct of sugar metabolism, although here the molecule is FADH2. 5:31 Second, complex II also transfers electrons between several redox centers 5:37 before donating them to coenzyme Q. One major difference, however, 5:43 is that complex II does not use the energy liberated to pump protons. 5:51 Coenzyme Q molecules from complexes I and II 5:55 donate their electrons to complex III. 6:00 One electron is a recyclable and can re-enter 6:03 complex III later, but the other passes through two 6:06 redox centers before reaching cytochrome c. 6:12 Cytochrome c carries the electron to complex IV. 6:17 The electron transport chain ends in complex IV, 6:20 where a series of reactions involving four electrons 6:23 converts a molecule of oxygen to two molecules of water. 6:29 The proton gradient is strengthened because four protons from the matrix 6:34 are incorporated into water molecules, and another four 6:37 are pumped into the intermembrane space. 6:41 In the absence of oxygen, the electron transfer comes to a halt, 6:46 meaning that ATP synthesis also stops. 6:49 Indeed, the reason we breathe oxygen is so 6:52 that it can serve as the final electron acceptor 6:55 at the end of the electron transport chain. 7:00 In this animation, we have explored each protein complex in isolation, 7:05 but in reality, they are very densely packed. 7:08 Together, they effectively make the entire surface 7:11 of the inner mitochondrial membrane a giant cellular power plant.