A Closer Look at...Stem Cells and Human Longevity

A Closer Look at...Stem Cells and Human Longevity University of California Television (UCTV) 118,109 views Jul 11, 2024 Can we live not only longer but healthier lives? Robert A.J. Signer and Shiri Gur-Cohen explore how stem cell research may unlock the secrets of longevity. Signer discusses the critical role stem cells play in combating aging-related diseases, such as cancer and immune system decline, by boosting their regenerative abilities. His work on hematopoietic stem cells and “super stem cells,” which better manage cellular waste, shows promise for delaying aging and preventing disease. Dr. Shiri Gur-Cohen examines how vascular and lymphatic systems support stem cell health, revealing new strategies for enhancing longevity and reversing the effects of aging. Don’t miss this in-depth look at the future of aging and human health. 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(https://www.uctv.tv ) 00:00 Start 00:23 Dr. Robert Signer 01:52 Looking For The Fountain Of Youth 06:40 Blood Forming Stem Cells 10:21 Proteins 17:39 Secret to Longevity 20:58 Dr. Shiri Gur-Cohen 25:36 Skin 29:10 Hair Follicles 33:08 Is The Vascular System the Key? 41:08 Tricking Old Stem Cells 45:51 The Fountain of Youth in the Vascular System? 47:28 Questions and Answers Chapters View all Transcript Follow along using the transcript. Show transcript University of California Television (UCTV) 1.34M subscribers Videos About Facebook 62 Comments rongmaw lin Add a comment... Pinned by University of California Television (UCTV) @uctv 3 months ago Check out "Reversal of Disease using a Whole-Food, Plant-Based Diet" here: https://youtu.be/BsbQuXxP_O4 13 Reply 1 reply @Hes1oscillations 3 months ago The first talk was great, a very impressionistic explanation of their research, certainly enough context to start reading up about it in more detail 10 Reply @msfifi8669 2 months ago Indeed, it’s an exciting time. Thank you for your hard work to improve health-span and thank you sharing your outcomes. 2 Reply @infact5376 3 months ago (edited) I am layman. I just wanted to bring into your notice there is something in UDST (Urine Devrived Stem Cells0 which helps longivity. Former Indian Prime Minister, Mr. Morarji Desai used to drink his own Urine every day and he became PM at a very late age and lived more than 100 years without any major health problem. His interview on this subject is available on BBC. Make sceientific studies if you can! There is a branch of study on this subject in ancient India, called Shivambu. Some literature is still available. 8 Reply 2 replies @marieeleonorespiritu4737 2 months ago Wow. I was a young nurse in the early 90s, attending an Apheresis conference in Houston, Texas. I can vividly recall s speaker introducing a modern plasma machine and mentioning the system to be the answer to finding the fountain of youth. Years later, I was working with a machine harvesting stem cells for cure in a research stage. I am now retired, and hearing these presentations indeed, pointing to yes, near the fountain of youth? Until this day, I only had seen the Trevi fountain 😂😊 2 Reply @arnobsaha5643 2 months ago Deep sleep and meditation boosts stem cells than any other food or any activity. 5 Reply @k.h.6991 3 months ago I found both talks fascinating. I would love more on how the lymphatic system works, in relation to cardiovascular health. 6 Reply @paulMcGlothin 2 months ago Brilliant presentation! 1 Reply @jakkigiles6446 3 months ago This is really interesting but I would be astonished if the drug companies allow this to become a reality. 5 Reply @eddyaboudi575 2 months ago Thank you for the information and your research. That’s a game change for a healthy living and lifestyle modifications Reply @Drowbackmountain 2 months ago Tnx for Great jobb for all over world,from norway ❤ 1 Reply @DungNguyen-fy1nt 1 month ago We really want to be immortal 2 Reply @rao-videos 2 weeks ago Good TV Reply @Jessica-kk1cz 3 months ago (edited) In terms of the gentlemen asking about timing - it’s ignorant to laugh. It’s not funny. For example, in ARPA-H, one criteria for funding is the - so what? And is your research going to have a real impact on peoples’ lives in a reasonable period of time? And as far as “you didn’t know cancer survivors before, and now you do” goes - we used to use rotary phones and now we have cell phones. Point is - now we have tools like epigenetic clocks, AI / ML, models on protein folding, better imaging technology, not to mention knowledge of bioelectricity (which also ties into cell differentiation), epigenetic reprogramming, mitochondria, quantum biology, etc. We don’t need studies about the limitations of rotary phones. It’s 2024, not 2004 or 1984. Different times, different measuring stick. Same for biomedical R&D, tech transfer, distribution. 14 Reply @carolapersoon7501 1 month ago @36min. Why the stem cells are near the lyfatic system. Maybe it is because it is the drainage. (There is no garage, almost all lymfatic fluids are recycled). The drainage will tell the stem cell about the health of the tissue and thus if repair is needed. 1 Reply @JosephArmbrister 3 months ago Interesting information 3 Reply @RobtJude 2 months ago Conclusion - As you get older things slow down and don't work as well as they did when you were younger.. 2 Reply 1 reply @avidey7050 1 month ago "Health Span" via Stem Cell "Breakthrough" 2025++ ? Appreciating, "Longer, Healthier Life" Mission. Thanks. Reply @sawairagul251 3 months ago Amazing explanation 🎇 Reply University of California Television (UCTV) · 1 reply @neurondcclxxvii 3 weeks ago Thanks for this share ❤ I have some follow up questions out of curiosity: @ Dr. Signer to control the myeloid overproduction, which is more economical to alter the instructions of mRNA not to produce such 'apps' or to target elimination of excess 'apps'? Or does it mean we can try to stop it at 'code' level? And for the HSF1 is it feasible to control their count? @ Dr. Shiri how can the structure of the lymphatic system nesting with stem cells be maintained indefinitely, (maintain a young environment from onset)? And is there a possibility to 'rebuild' the old environment ? Or what's the feasibility of introducing an artificial young environment within the old environment? Reply @sfrotc_com 2 months ago ❤❤❤❤❤ 1 Reply @TheDanEdwards 3 months ago (edited) The talk associated with DNA, by Dr. Signer, is very ladened with teleology, which is quite out of place in the scientific endeavor. 5 Reply 4 replies @jordistulen4565 3 months ago In mouse studies daily calorie restriction shows exponential life span extension, but protein restriction not so much, only a bit Reply @syedsalman7657 3 months ago Amazing insights and excellently presented ❤ Reply @黃金山NGKIMSAN 3 months ago Lifespan hopes and dreams Reply @jayyoo906 3 months ago Any communication method between the stem cells? How to transfer genetic heritage? Reply @BaccaratKingmaker 1 month ago NVIDIA ❤❤❤ Reply @RoshanPatel1441 2 months ago Suffered TBI Thematic Brain Ingery from a motorcycle 🏍️ in 2016 currently wheelchair bound currently,🕉️✌🏾 Reply 4 replies @heart-of-people 1 month ago I have never talked to the stem cells, cells, mitochondria, or white blood cells in my body, and I have never told them what to do, but they do their jobs on their own. Are they autonomous robots? 1 Reply @susymay7831 3 months ago Timestamps would help your nice videos ❤ 1 Reply University of California Television (UCTV) · 1 reply @Jessica-kk1cz 3 months ago (edited) Talk one - great! But what ARE old super stem cells, and how do you make them? Is this published anywhere? That was the most important part. Is this in mice or people? Talk two - ok, so the supporting lymphatic / vasculature for the stem cells is more important than just the stem cells alone. So if there is no way to fix the lymphatic / vasculature - who cares? This talk is premature and irrelevant to people. Come back when you have a solution to fixing the lymphatic / vasculature for stem cells - or at least learned something that does not work so it’s not repeated. Otherwise this was a waste of time to watch, and a waste of funding to do unless the goal is to just sit and look at stem cells not performing well because of lymphatic vasculature. Pretty irritating actually when scientists think the point is their own self indulgence. 2 Reply @geoffmccoll4640 2 months ago Um, if you are male aged 69. Should I get younger? Reply @saturdaysequalsyouth 3 months ago How strong are those bites? Looks like they can take a finger clean off by accident. Reply @MalongayGonzales 3 months ago This idea is good but all people don't understand not at all people understand its very long long way to frame exaplaining to people Reply @RJay121 2 months ago Bummer from the Comments this vid post sounds more lecture than prescription😮 Reply @andrewwalker8985 3 months ago Hey, this isn't Seth Meyers Reply @GabrielPradi 2 months ago Just eat papaya everyday Reply @DeepuKujur-u3w 3 months ago Waw😊 Reply @rao-videos 2 weeks ago Mouse Reply @FalafalGrease 2 months ago Umbilical cord juice😂 Reply @anonviewerciv 3 months ago The benefits of slowing down. 🦥(12:07) 1 Reply