Saturday, October 12, 2024
Electron transport chain
0:32 / 7:44
Electron transport chain
Harvard Online
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From our free online course, “Cell Biology: Mitochondria”: https://www.edx.org/course/cell-biolo...
Harvard Professor Rob Lue explains how mitochondrial diseases are inherited and discusses the threshold effect and its implicati …
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5 years ago (edited)
Learn more in our free online course, “Cell Biology: Mitochondria”: https://harvardx.link/pwnt
Transcript
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0:05
RL: All eukaryotic cells, from yeast to those that make up the human body,
0:09
contain membrane-bound organelles with specialized functions.
0:13
Mitochondria are double-membraned organelles
0:16
that harness most of the energy that cells need to grow and reproduce.
0:23
Nearly all of this energy comes from reactions that take place
0:27
at the inner mitochondrial membrane.
0:47
One of the key roles of this membrane is to act
0:50
as a barrier to positively charged particles
0:53
called protons, thus allowing a concentration
0:56
gradient to be maintained where the intermembrane space has
1:00
far more protons than the matrix.
1:09
The membrane also contains a large protein complex called the F1F0 ATP
1:14
synthase, which uses the proton gradient to drive
1:18
the synthesis of ATP molecules.
1:23
These ATP molecules ultimately provide the energy
1:26
for most of the cell's reactions.
1:29
Just as man-made power plants produce electrical energy
1:33
by using the flow of wind, water, or steam to rotate a turbine,
1:38
the synthase makes ATP by using proton flow
1:42
from one side of the inner membrane to the other to rotate protein subunits.
1:48
If there is no proton gradient, synthase subunits stop rotating,
1:53
and the cell can quickly become starved of the energy and die.
2:04
Therefore, the protein complexes and small molecules
2:07
that establish this gradient and maintain it
2:10
play an essential role in the life of the cell.
2:15
At the heart of this system are four protein complexes
2:18
numbered I through IV.
2:24
Complexes I, III, and IV directly pump protons
2:28
from the matrix into the intermembrane space.
2:36
Complex II does not directly pump protons,
2:39
but it does promote proton pumping in complexes III and IV.
2:50
Proton pumping requires energy, and the four protein complexes
2:55
get this energy by transferring electrons
2:58
through a series of coupled reactions.
3:05
This linked process of electron transport
3:07
is why the four complexes are collectively referred
3:10
to as the electron transport chain.
3:17
Let's focus on complex I. A byproduct of sugar metabolism
3:25
called NADH deposits two high-energy electrons
3:29
in complex I, where they are passed along a chain of redox centers.
3:38
Redox centers are clusters of atoms that have
3:41
different affinities for electrons based on their unique atomic configurations.
3:48
Let's closely consider a pair of redox centers
3:50
to reveal two reasons why an electron moves from the top redox center
3:55
to the bottom.
3:57
First, the bottom redox center has higher affinity than the top one.
4:04
Second, the distance between these adjacent redox centers
4:08
is ideal for an electron jump to occur, which explains why electrons typically
4:12
don't bypass the bottom redox center.
4:26
A small amount of energy is released each time
4:29
an electron is passed between redox centers.
4:33
Complex I harnesses this energy across all the redox centers
4:37
and uses it to pump protons.
5:02
The last redox center in complex I donates two electrons
5:05
to a coenzyme Q molecule.
5:14
Complex II is similar to complex I in two important ways.
5:19
First, high-energy electrons also enter complex II
5:23
via a byproduct of sugar metabolism, although here the molecule is FADH2.
5:31
Second, complex II also transfers electrons between several redox centers
5:37
before donating them to coenzyme Q. One major difference, however,
5:43
is that complex II does not use the energy liberated to pump protons.
5:51
Coenzyme Q molecules from complexes I and II
5:55
donate their electrons to complex III.
6:00
One electron is a recyclable and can re-enter
6:03
complex III later, but the other passes through two
6:06
redox centers before reaching cytochrome c.
6:12
Cytochrome c carries the electron to complex IV.
6:17
The electron transport chain ends in complex IV,
6:20
where a series of reactions involving four electrons
6:23
converts a molecule of oxygen to two molecules of water.
6:29
The proton gradient is strengthened because four protons from the matrix
6:34
are incorporated into water molecules, and another four
6:37
are pumped into the intermembrane space.
6:41
In the absence of oxygen, the electron transfer comes to a halt,
6:46
meaning that ATP synthesis also stops.
6:49
Indeed, the reason we breathe oxygen is so
6:52
that it can serve as the final electron acceptor
6:55
at the end of the electron transport chain.
7:00
In this animation, we have explored each protein complex in isolation,
7:05
but in reality, they are very densely packed.
7:08
Together, they effectively make the entire surface
7:11
of the inner mitochondrial membrane a giant cellular power plant.
2,142 Comments
15 replies
@LavenderTheArj
4 years ago
I remember when I was studying biochemistry II in my bachelor's degree, desperately looking for a video on this on the night before the final exam, didn't find one and had to memorize it the old fashioned way, all I'm saying is that what you're doing is extremely valuable for a lot of students, best of luck.
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25 replies
4 years ago
Imagine a whole biochemistry book animated like this... I wish I'd be alive till then :'(
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31 replies
@nickmagrick7702
4 years ago
the visual explanation really helps a lot.
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@cadenketchman2000
1 day ago
This was literally perfect
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@medni6311
1 month ago
What a fantastic voice with excellent teaching methods. Stunning education approach. Thank you from the whole heart, not just from the bottom. I am leaning toward to derma specialty, and without knowing all these fantastic body processes, it is impossible to deal with skin issues.
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@killianoshaughnessy1174
4 years ago
I am amazed at the complexity of being alive.
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41 replies
@Roger-go6jc
1 year ago
This is just awesome. I'm 69 now and still doing paediatric nursing, but started my career in Pathology. I remember pawing through my Biochemistry text to sit exams and trying to memorise the Krebs Cycle, which is all part of this. But the process I did on a page that showed chemical energy utilised for cellular respiration has just blown right off the page. This visual takes me into a Mitochondria and starts to put the cycle into a visual sense. What a wonderful progression in knowledge we have.
Now lets not forget who we are and what a beautiful planet we have.
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@vedantbhardwaj7582
9 months ago
I'm a medical student at King's College London, and honestly this has helped me sooo much with actually being able to visualise how Oxidative Respiration actually occurs! Thanks!!!!!!!!
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3 replies
@TSUKI_3.
3 weeks ago
So what do complex 2 & 3 do with the energy they get from the redox centers if not pumping protons?
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@PlateletRichGel
3 weeks ago
Why do i get vivid dreams when I take Coenzyme-Q? Is it the better activity of electron transport in my brain cells.
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@noelsrx376
4 years ago
This is physics, chemistry and biology combined in one! And I love it!!
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36 replies
@hosoiarchives4858
2 years ago (edited)
0:29 inner mitochondrial membrane
0:47 key role is to separate protons, inner from outer protons
1:08 ATP synthase, makes ATP. Uses proton flow to work
2:24 Complexes 1, 3 and 4 pump protons out
2:49 complexes get energy from electrons
3:18 complex 1 uses NADH and reduces it
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@Lisargarza
2 years ago
Learned all this stuff in grad school 40 years ago, but it was more like a concept, a chemical formula written on a page. To see it spring to life as an animated video is astounding. Thanks for posting.
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@audreyanderson7042
3 months ago
Question: If complex II doesn't harness that energy from the electrons skipping redox centers, what happens to it? Does the energy stay with the electrons until it gets to complex III/IIII or maybe it helps shuffle coenzyme Q along?
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@lastyhopper2792
2 years ago
This looks soo fun...
I want to know what aspect of those system can be optimized and fine tuned
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@Ronin777z
3 years ago
The animation was incredibly helpful in understanding the material. My mind tends to wander during lessons so the visual aspect was immensely helpful.
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@hasen_judi
4 years ago
"and this is why we have to breath oxygen" was a mind blowing moment for me.
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@aryansaeedi7618
4 years ago
My god what a beautiful video. Very clear and well explained. I’m in love with this channel.
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@CloudScience
2 days ago
❤❤❤❤❤❤
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@JMYaden
6 months ago
These clever animations really make this whole fascinating process come alive. Thank you! I will take your free online course!
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@lucachirico4183
2 years ago
I watched this video 3 years ago for the First time, when I was studying biochemistry for the exam of the bacheloor degree. Now I've just re-watched it to review the topic at all for work, and it's gorgeous like ever. I think immagines and videos can teach better then thousand of a book's pages. Colours and animations are for me the best way to rember and put every feature in our brain.
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@raplopez4258
3 years ago (edited)
What makes this video stand out is not just the breaks, but the respect for the student, BY GIVING US 5-30 SECOND BREAKS TO JUST RELAX THE BRAIN!!!! (*Cough to all you other science videos/teachers out there cough cough*)
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@jayski9410
4 years ago
I wish we could have had visualizations like this back when I was a pre-med student in the 1970's. All we had were acronyms, arrows, and line drawings. The best analogy I can come up with is a wrist watch - in my day we could look at the watch face but just read about what made the hands go around; this animation is like opening up the back of the watch and finally seeing all the gears and springs in action.
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@audreya7543
5 months ago
This is easily the most clear-cut and visually useful aid I could find online to look at the ETC complexes 1-4. I can't thank you enough for this resource!
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@NebelmondDso
5 months ago
In which form is the Energy of the Electrons between the redox centers passed on?
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@makaylamoore8831
4 years ago
Such a great, clear explanation! Videos like this remind me why I love biology so much. Life is amazing.
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@TommyTumma
9 months ago
Professor Lue’s microbiology course at Harvard was really easy to understand. The hallmark of a great teacher. I recommend taking his full online class for free!
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@edehc
3 years ago
INSANE IN THE MEMBRANE! AND ALL OF THIS IS HELD TOGETHER BY DIFFERENCES IN ELECTRICAL CHARGES? JUST WOW…
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@coopdeville4933
6 months ago
This video illustration is one of the best things I've ever seen. I can see I should have been a biologist. This is one big beautiful puzzle that I must solve, even on my own time
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@noisepuppet
1 year ago (edited)
We need a single illustrated page explaining this with bullet points that users will understand at a glance.
--IT Management
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@rolandoe.diazolivom.d.4777
4 years ago
Congratulations for this excellent video. Next up, please: The microscopic machinery of the outer mitochondrial membrane. This is the gatekeeper preventing a massive influx of H+ and other cations in the surrounding matrix from entering the inner mitochondrial matrix.
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@Darkmatter321
4 years ago
This happens a few Trillion times a second in our bodies. No big deal!
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57 replies
@stephenarmiger8343
2 years ago
Reading Brian Greene’s book, Until the End of Time. He does an admirable job explaining this. I appreciate this attempt to help us understand the situation in three dimensions!
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@DebashisChoudhury-ff4cs
3 weeks ago
Thanks it was really helpful ❤❤
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@barry7608
2 years ago
A bit over my head but extremely interesting, thanks. Would it be fair to say this is an electro mechanical process, you did say the proteins are made to rotate?
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@divinephanes
3 years ago
I remember seeing this in my first year bio class, it blew my mind when I first saw it and it still does. Thank you for this!
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@lilyilyily323
3 years ago
RIP prof lue, this video is just one of many thousands of wonderfully helpful, selfless things he contributed to the world during his too-short lifetime.
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@SoirEkim
4 years ago
I may not be fully aware of what it took to put this information together. Yet, I love learning in this way and the visuals are mesmerizing. Therefore I would willingly watch several days worth of videos like this. Excellent! Thank you.
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@theSilentPsycho
4 months ago
Thank you for creating this video. As a software engineer, I've always been intrigued by understanding the intricacies of how things operate on a smaller scale. Your video also highlights how we often operate in our professional lives akin to machines, much like the mitochondria units showcased, and how this can sometimes obscure our awareness of the broader universe to which we belong. It serves as a reminder that we each have a unique purpose within this vast ecosystem.
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@-_Nuke_-
1 month ago
Im confused, are these things inside the mitochondria? Or outside?
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@kritikathakur5895
3 years ago
We want animations like this really. They helps us to have a deep insight in the topics. Thanks
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@yvonnemoreno8805
3 years ago
This is amazing. It puts all these concepts we're inundated with and makes it more clear. As a visual learner, I wish there were more animated videos like this!
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@andychow5509
4 years ago
Wow. Amazing how much progress and knowledge we are starting to have access to. Never saw anything like this when I was growing up.
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@ronp5615
3 years ago
Did you license this from the Markovians? :-)
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@WildlifeGuy
1 year ago
I wish I had these types of videos when I was getting my Biology degree back in 2001.
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@peterschmidt1453
3 years ago
We can thank Drew Berry for pioneering the animation of this invisible world, his ability to visualise these subatomic processes has made these animations possible.
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@rcarmisin3465
4 years ago
I got so lost watching this video, it was 20 minutes later until i realized i was staring at the wall. lol :)
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@iainmacdonald8379
4 years ago
I'm reading The Vital Question by Nick Lane and this video really helped me to understand respiration, particularly redox. Fantastic book, by the way.
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@akashhera
3 months ago
Undoubtedly the best animation in this topic out there!😍
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@kamalim982
10 months ago
Woah! The best one i have ever watched and ur prounciation is just awesome 👍 thank u sir😊
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@fzka_
4 years ago
This is such a good visual explanation. Thanks!
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@igoralencar4817
4 years ago
This is so beautiful. I've been looking at it for five hours.
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@ectogamut
4 years ago
5:19 The shark tooth ghosts show up, get their eyeballs, and leave.
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10 replies
@atharva7375
3 months ago
Mindblowing visualization... I had doubt in ets in my class 11th respiration chapter... But now this is gonna be my favourite part of the chapter 🔥🫶🏻
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@MaverickMusic-fu1yt
3 months ago
You are fearfully and wonderfully MADE. God bless you everyone. You are more valuable than anything else in this world.
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@jesusmiguelalvarezfernande8761
2 years ago
Just the opposite of what happens during photosynthesis in chloroplasts. What a wonderful balance!
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@PheedPhil
3 years ago
Great video. Haven't seen a better animation anywhere else. And very accurate too, with the exception of one small detail (which most text books also get wrong). FADH2 is not the electron donor to complex II, it is physically attached to the first protein of the complex (a flavoprotein). Succinate is the electron donor (CII is called succinate dehydrogenase) and CII oxidizes it to fumarate in the Krebs cycle, passing the electrons to it's FAD, and onward into the complex.
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4 replies
@geofractal
4 years ago (edited)
This is incredibly amazing. It is also amazing that humans can figure this out -- very smart humans, that is.
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6 replies
@droidsuperuser
7 months ago
Which Energy form does complex use to pump proton?
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@IzzytMe
3 years ago
So I can actually harness quantum energy in each cell of my body, simply by breathing oxygen and my teacher said I'm no good at physics. That can't be right!
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@danteseluvathingal5292
5 years ago
That was amazing.thanku soo much
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@ngc-ho1xd
4 years ago
Life is the ultimate Rube Goldberg machine, that in essence performs a task very similar to Maxwell's deamon. It's so beautiful!
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@AmaraofEarthWithTheLavaCore
1 year ago (edited)
What is the energy generated from complex 2 used for then?
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@MichaelHarrisIreland
1 month ago
Thanks, great video.
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@writer24x7
4 years ago
4:26 A small amount of energy is released? Energy in what form? How the complex harnesses this energy?
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1 reply
@tag180rotax
2 years ago
Mitochondria is the powerhouse of the cell
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@nikitasid4947
4 years ago
That feeling when you read an offline paper book on Mitochondria and then Youtube recommends you this.
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3 replies
@michaelrowland-us3he
5 months ago
Where does the water in cellular respiration go to?
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@riponsutradhar2908
4 months ago
One of the best animations & explanations available in the internet regarding electron transport chain.
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@mingngyt
4 years ago
This was beautiful. amazing music and lesson.
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3 replies
@dickmorhead6165
4 years ago
I have my mother's eyes and my mother's mitochondria.
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@rachelchristiansen9218
4 years ago
I was literally feeling so screwed over my biochem exam because i could NOT grasp this concept. This was so clear and easily explained and I feel way more confident going into my test, and better yet it was INTERESTING and easy to continue to watch. Thanks!!
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@罗巧
2 years ago
This is so helpful! And I wonder in anaerobic conditions would the only difference be terminal EA.
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@1eingram
3 years ago
Can nadh and fadh also synthesize atp from fat and or ketone metabolism?
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@rodneywar
4 years ago
Thank you for sharing this highly educational video.
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@greggrobinson5116
3 years ago
Seeing this chemistry written out as reactions is impressive enough, but seeing it animated is just astonishing! And to think that this is going on effortlessly in every one of our cells all the time is downright religious.
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@fotoflo
4 years ago
4:26 - "a small amount of energy is released each time an electron is passed between redux centers" -- in what form is the energy released and stored?
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40 replies
@prestonburton8504
9 months ago
amazing -
i had to 'memorize this' to pass engineering late 1970s - there was nothing like your incredible animation and description.
memorizing it? didn't mean i knew it -
i do now, thanks to you!
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@ematthews6642
1 year ago
If I am being asked to define the three main energy carriers in this process, is that the protein complexes 1, 3 and 4? Please can someone tell me if I am correct?
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@An0nim0u5
5 years ago
Please can you guys make a video on Photosynthesis as well...???
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@samp-w7439
3 years ago
The fact that this is constantly going on in our bodies is insane. The fact that people have somehow figured out all the details and intricacies of this tiny and complicated processes is on a whole other level!
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@BramMichaelson
4 years ago
I think I've seen all this before when I got REALLY high.
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@morritzmiller3863
2 years ago
have you considered making a video of the membrane transit animation but with lo fi beat to study too? it would drive up engagment.
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@victormaxwellpeters9771
1 year ago (edited)
In which form the energy is released when an electron jumps from one redox centre to another?? Is emf induced by moving electrons??
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@ferid9k
3 years ago (edited)
1:40 thats actually just a theory.We still dont know how atp synthase works
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@howtogaintime739
4 years ago
What a beautiful little world, wish I could see it up close.
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4 replies
@rodschmidt8952
4 years ago
When the gradient is insufficient and the mitochondria no longer produce ATP, the cell can become starved of energy and -- become cancerous? Are not small amounts (~5%) of ATP always produced elsewhere in the cell by fermentation?
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@dingdong6259
2 years ago (edited)
so we have an 200 rpm - ohc motor with the camshaft opening and closing an atp synthese and propulsion system? (how) does it sort out atp between "loose" and "tight"??
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@sunshine_of_csy
1 year ago
This is such a dope video for ETC,I am totally visualizing what I have read in books
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@redemptivememelord6283
3 years ago
For once I read it as "Electron transport chan" and I thought I'd meet a molecular biology waifu
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2 replies
@denisa.6793
4 years ago
oh my god, i praise the author, incredibly helpful
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@ElectricityTaster
4 years ago
ahh yes, the powerplant of the cell.
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@fabiobarreiro
4 months ago
It's almost unbelievable how complex and precise life is. A lot of hard work to keep us alive.
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@NdendahayoJeanclaude-kk2go
2 months ago
Hello, i am from RWANDA ,i wish to get educated in HARVARD MEDICAL school , how can get in touch of it , help me please .
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@Vivanwho
1 year ago
How did mankind find this out. It's still so bizarre
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@opeoluwaabiona3898
4 years ago
0:40 : Wow, this is like an endless ball pool!
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@neigeepierrot4694
4 years ago
Amazing this happens everyday
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@kitony
3 months ago
Students life must be great with these animated videos and AI.
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@rhosoojin191
4 months ago
This animation is so beautiful and well made ❤
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@Bitmaker64
4 years ago
Who else just likes to see this animations.
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@oleksiyalkhazov9201
4 years ago
Science is the best mystery and greatest magic in the multiverse
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@kaukabbhatti1661
4 years ago
To be honest, this is the best animation I have seen on this subject.
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@jimking6484
3 months ago
Fantastic explanation! Thank you!!
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@manurenier2534
1 year ago
amazing video, we biochemist students from KULeuven (Belgium) love this !
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@xinchen3547
3 years ago
Respect to the masterpiece of the Creator, and the marvelous job of the makers of this video.
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@schunack6433
4 years ago
It’s actually called FoF1 ATPase not FzeroF1 ATPase; great video otherwise!
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@yvonneott8758
4 years ago
Primordial soup, or magic potion?
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@narek335
3 months ago
This is my favorite biochem. video ever
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@ashypharaoh8407
1 year ago
Who else is carrying out oxidative phosphorylation while watching this?
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@MichaelBethel
3 years ago
This really amplifies the words of the Psalmist when he says "I will praise You, for I am fearfully and wonderfully made; Marvelous are Your works, and that my soul knows very well." Psalm 139:14
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@linenkeyes6329
2 years ago
Anyone else here from meow wolf?
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@sangitasharma4692
1 year ago
This is one of the best animation video i have ever seen with such a great and clear explanation
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@michaelrobinson9952
6 months ago
The line between the three big scientific disciplines becomes blurred here, wonderful.
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@KatherineShay
3 years ago
Who is here from Meow Wolf??
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@raymondndungu6447
11 months ago
May the Lord receive the glory due His name! He has created us amazingly! And yet, despite sinners’ rebellion, God sent His Son Jesus Christ to live the perfect life and die a ransoming death so that those who believe in Him might not perish but have eternal life.
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@theconfussy924
6 months ago
Neet ug aspirant👍👍
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@themedico20
1 year ago
My test the day after tomorrow loses its nightmarish vibes because of this video! Thanks a lot.
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@nightshade2826
2 years ago
Hello, I have a question, at the start of the video we are talking about protons floating around but aren't protons a part of an atom's nucleus? How can they possibly be free from it? Maybe I am misunderstanding this because eng isnt my native language. But I am very confused.
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@Mighty_Deeds
2 years ago
God's craftsmanship. A design of perfection.
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@aryaardiodio
2 months ago
God is Great
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4 years ago
God made all of this as if we make a rag doll.
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@abdulmajid427
1 year ago
The same topic I've been taught regarding Respiration in plants, the following week & I'm taking this vid as revision purpose ❤
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@omarelkhateeb6269
1 month ago
Impressive , thanx
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@josevictor6687
1 year ago
We see in The Perfection of The Creation of The Lord God.
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@michaelayeni177
4 years ago
Glory be to God
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@dedo9777
2 years ago
Does anyone know the name of the music?
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@Sidguru101
1 year ago
explained so beautifully yet its so vague thinking about all these processes occurring all at once
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@gilsai4990
8 months ago
wonderful explanation! very helpful :)
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@EarthGoddess369
4 years ago (edited)
Awesome!! I'm particularly intrigued with the reason why we breathe .. I'm working on a book and it ties in exactly with my theory .. Many thanks 🙏🏽 Is that a slight Jamaican or other WI accent i detect in the Narrator' s voice.. ?
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@aztecburn115
1 year ago
The ATP synthase membrane portion isn't called F0 but Fo by oligomycin the inhibitor
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@Jere616
4 years ago
Since the main work of the chain is to put protons into the intermembrane space, why are the 4 complexes called the electron transport chain instead of the Proton Pump Complex?
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@sinayasharabi8302
1 year ago
I have recently been obsessed with animations of this theme, they are simply fascinating.
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@johannamarianfinos9781
1 month ago
best video ever!
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@helmutzollner5496
1 year ago
Great Animatiin. It makes this complex subjevtbso much more tangible. Thank you.
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@apothecurio
2 years ago
The jump from atomic particles make a thing that is deemed as a system that sustains itself had always fascinated me and ,as a lowly layman, found it hard to actually find where I could find that info. This is the perfect start. Amazing.
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@addictionmystyle3718
7 months ago
This type of videos are valuable. These non seen tiny creatures are doing their best amazingly. But why they are do their duty for us...?it's complicated. So we have lots of responsibilities. Nowadays science students are blessed and I wish they need to see it.
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@james7951
7 months ago
How is this so beyond helpful??? 😂 Amazing work. I understand this so much better now
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@MirjamMoutaj
6 months ago
This video is amazing, thank you!
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@jerryo1228
1 year ago
Excellent video, with very complex processes; explained clearly and easily to understand.
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@AmruMagdy
11 months ago
Such a great, clear explanation! Videos like this remind me why I love biology so much. Life is amazing.
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@YDDIGC
3 months ago
Thank you, you have my deepest blessings ❤❤
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@sanjibsarmah1582
2 years ago
Most effective and easy understand elaborative video ever
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@climateguy2488
1 year ago
Just wonderful. In awe. I wish i went into this field of work
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@BushCampingTools
4 years ago
Just the best! My 9 YO is learning all about this; why? he asked me why will we die if we don't breath oxygen, this created for me to teach him about the: ETC, Mitochondria, poisons of the ETC; proteins etc etc. Plus Organic chemistry LOL. Who says kids can not learn and understand this stuff. Why it's not taught at junior level i have no idea, especially when they are so curious at a young age. The animations really help with the understanding. Like why the proteins are shaped like they are; another great avenue to pursue with some organic chemistry etc. tie it all together kids love it.
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@Daniel-xh2xf
1 year ago
At 4:25 we see the electron transfer between redox centers releases energy, which in the case of complex I is used to pump protons.
At 5:31 we see the same phenomenon occur in complex II so we would expect the same release of energy, however here this energy is not used to pump protons. What happens to this energy?
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@shanthala1345
2 years ago
What does complex 2 use the energy for
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@turinmormegil7715
4 years ago
When you say the lack of O2 means halt in the ATP synthesis, is it because the pumping of H+ (8 molecules = 2 Water + 4 protons, specifically for Complexe IV) won't be completed, thus nullifying the constantly kept gradient or simply because, before the gradiente suffers, there won't be enough H+ to move ATP Synthase? If so, but what abbout the protons that were already pumped by complexes I and III into the intermembrane spcae? They don't need Complex IV to finish their own pumping.
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@JohnHillEU
2 years ago
Very newly interested in biochemistry and it's amazing to see the similarity in the proton concentration gradient has with the mechanisms at play in silicon transistors!
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@danielduarte5073
10 months ago
Outstanding information!!!
Well done!!!
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@myblueparadise5807
1 year ago
This is the best animation I've seen so far....I just have no words to appreciate you❤
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@alfrednewman2234
2 years ago
fantastic. Love Nick Lane's contribution to Kreb's citric acid cycle, and life's origins/cancer's abbherration
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@uremcolo9489
1 year ago
Please what does complex 2 used the liberated energy to do? Somebody help 🙏🏾
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@skitoes974
2 years ago
The only video I could understand as I'm about writing my biochemistry exams thanks 🙏
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@Raja-kr8ul
1 year ago
Thanks for your video sir. Excellent video sir. Excellently explained. God bless you.
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@MrZooganopolos
3 years ago
That was a lovely and descriptive review! Thanks for taking the time to make such a great video!
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@jadhavaniket100
3 years ago
I was searching for a perfect explanation for the ETC and couldn't find any. Came to YouTube and saw your video and was blown away. Thank you so much. It shows that it has taken immense efforts to create this amazing video. Thank you once again..
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@yeahitsok3246
6 months ago
This Helped me out in MBIOS 303
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@MiG-17
2 years ago
This makes me remind when i was in high school! Nice video.
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@aylinm5439
2 years ago
I love how he stops occasionally, so the knowledge sinks in.
Thank you so much, helped alot.
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@Marco-xz7rf
2 months ago
so what frequency should i pllay to my body in order to get electrons to flow in my cells and drive these complexes without nadh+? I mean this somehow should be possible?
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2 replies
@amelghwel
1 year ago
Thank you so much for this video! I'm studying Biochemistry II and this is the very first time I understand completely how electron transport chain works. Thank you very much for your efforts.
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@mrinalsahu7991
7 months ago
Explained everything so beautifully
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@michaelK.3272
2 years ago
This is one of the most informative videos I have ever seen. Excellent quality. Thank you!
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@jimpaine6331
6 months ago
What a fabulous video!
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@maryamfazal3180
2 years ago
No other video could convey the concept that this video has conveyed. Best video ever, I'll never forget ETC ever again.
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@aasansathyamoorthy
1 year ago
Excellent video.Thanks a lot.
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@Geminish15
7 months ago
I could tell by the background music right away this was gonna be legit with the visuals
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@laurarebecajimenezgutierre78
5 months ago
great video
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@motivational..3
2 years ago
A very helpful animation that cleard the my whole doubt about this concept
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@hikolanikola8775
4 months ago
why is there no more research done on this topic?!
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@theresaditz6271
1 year ago
Thank you from Düsseldorf -Germany. I study medicine and this saves me!
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@damoneaves
2 years ago
This Animation appears to scale. Love it. THANK YOU for the animation and narration it’s great. Nerd/dork manna from heaven
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@miray3663
7 months ago
it was great, thanks
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@mqttia-1924
11 months ago
well animated thank you
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@andrewflowers1755
2 years ago
FASCINATING/BLOWS ME AWAY !!
⭐💪🦾💥🔥💫💫💫
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@ashitkumardutta6582
1 year ago
Addresses to all the small details! outstanding!
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@clairerolland7239
1 year ago
It's so beautiful, I'm lacking of "adjectifs" ! You are the Michel Ange of the life views of cells. Thank you so much ! when looking through mirror, I shall see another ! I would like to be younger and join your studies ! so gracefull
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@Coppermeshman
4 months ago (edited)
Life so delicate, yet so much potential.
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@chaosevolution
1 year ago
Clear & concise. Thanks.
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@baraskparas9559
1 year ago
Great presentation
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@jainsanskar722
11 months ago
Very helpful thank you
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@AyeshMedic
2 years ago
This was Amazing!!! The most distinct video of it's type. I was having so much trouble in ETC and here it is in such an easy way. Good Job.
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@Uruba_Rais
2 years ago
great.. help in visualising and understanding
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@MBison-im2qy
3 years ago (edited)
In Complex #4, a reaction of 4 electrons converts a molecule of Oxygen to 2 molecules of Water. Please explain that.
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@bharathwajramesh4712
1 year ago
you ppl really deserve millions of subscribers.!!!!!!. really great
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@lecturestudio4640
2 years ago (edited)
I wish these resources were present when I was doing my graduation studies. Would have made my efforts so much more mindful and meaningful
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@didijaja8973
1 year ago
Thanks a million for this video
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@fritsgerms3565
3 years ago
marvellous. as the modern view is that electrons are excitations in the electron field, I find it very hard to visualize the processes that are shown so nicely here. I wonder how accurate this visual animation is.
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@SolveEtCoagula93
2 years ago
I have SO many questions! But, can anyone tell me how the liberated electron energy in Complex 1 is 'harnessed'? I mean, the electron loses energy (is this a quantized, or a translational amount of energy?) but exactly what form is this energy in, and where is it stored in order to then be harnessed? My sincere thanks to anyone who offers help!
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@matyasmatta
11 months ago
Unbelievable. So beautifully animated.
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@shinn-tyanwu4155
1 year ago
Great lecture 😊
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@Ren-v9m
2 years ago
This is extremely helpful for me !!!!!!! Super grateful for the master piece that you produced !
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@ranimeher1725
1 year ago
Superbly explained💕
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@rickaguilar1833
1 year ago
I wish they had this computer animation when I took my medical school biochemistry courses!
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@cholabit1532
1 year ago
Chills! Literal chills❤
Mahn, I love every second of this video ❤❤
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@Mateo-jc9zg
2 years ago
amazing video, keep up the great work!
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@letsgo4834
3 years ago
Beautiful. I wish I’d had this type of material from which to learn and review years ago.
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@ghulammustfa9217
2 years ago
Very good explanation thank you so much❤️
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@bettyswollox8020
1 year ago
Amazing. Thank you
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@konstantinmymind180
2 years ago
But how dose coenzyme Q know where to go. Is it that it goes to the compound nearest to it and why dose it not go back to the same compound
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@asicerik
2 years ago
How in the heck was all this figured out? Amazing stuff
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@idegteke
2 years ago
Yes, I thought it might work like this, but thank you for providing some extra details:)
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@fangugel3812
2 years ago
Very nice. It would have been great to show this to students when I was teaching biochemistry.
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@BenjaminHaukaas-l1t
1 year ago
Very good!!
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@Dazzletoad
10 months ago
Absolutely magnificent :D
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@shelan7058
1 year ago
5:42 what does Complex II do with the energy then?
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@memogap88
2 years ago
min 6:27 is it correct to state that 4 electrons turn one O(xygen) to two molecules of (H2o) water ? Surely this could have been stated better.
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@m0sbah4
2 years ago
this one of the best explaining videos i had ever seen
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@VileVictour
2 years ago
I was scanning random qr codes I convergence station in Denver and this was one of the video's
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@nikhatreena2461
4 years ago
Out of world work,,such a hard topic explained in a cool fashion,,kudos to your work and thank you so much 🔥🔥
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@guillermolopezlluch3065
13 days ago
In complex II there is a minor mistake. It seems that FADH2, as NADH is soluble but it is not. Is succinate that transfers electrons to the resident FADH2.
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@evanquinn6092
4 years ago
This was an amazing video, you didn’t skip info and make it confusing thank you
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@paolopenna2668
2 years ago
Compliments! Is very complete and esaustive explanation of this argoment.
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@BushCampingTools
4 years ago
Wow great video for learning about the etc! I've subbed! I never had anything like this at uni.
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@linubindhuprakash912
2 years ago
Awesome work ... Thanks a lot🌠
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@ollipolli6325
2 years ago
Amazing and incredible job to do such a video !!!
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@johnathanh9369
3 years ago
I start off watching videos then I dig into the textbook so then I can imagine it. This allows me to memorize and understand it better.
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@eloimumford5247
2 years ago
Bright brains and lot of knowledge condensed in a short video , thanks.
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@semexambcma
3 years ago
Just mind blowing. thanks you all of the team.
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@betula-pendula
11 months ago
It is so fascinating!! I nearly can't stand it. 😳 Unbelievable fascinating!!
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@brucejohnson5786
3 years ago
Dude this just blew my mind. Thanks, it really clears things up
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@bengipolat3791
3 years ago
Such a great video thank you it helped a lot
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@fatimafunes7009
1 year ago
Excelent. Thank you!!!!
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@mjllle6603
2 years ago
best video for understanding ETC 👍🏼👍🏼👍🏼👍🏼👍🏼👍🏼
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@JHilak
3 years ago
its like micro-starwars! but what exactly happens when the redox centers in the proteincomplex send green circles and the protons are pumped?
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@doreenbachmann5508
3 years ago
beautiful video and lovely voice thank you!
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@yashjoshan233
2 years ago
Never thought that I can understand this topic so easily like within 7 minutes... all credit goes to this animated video thnq so much
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@usaidmahmud3964
3 years ago
This helped so much, thank you!!
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@ramadhanoruch8463
2 years ago
Fantastic explanation..
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@rosannaalexis
2 years ago
So beautifully intricate. Thank you for this video!
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@KerriWest911
4 years ago
This is beautifully done and informative.
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@malorie1042
3 years ago
Love these videos. So so so much easier to understand & learn.
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@rebecafreitas5061
3 years ago
Wow, thanks for this great animation! It's fantastic
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@jansigayan
6 months ago
Amazing
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@jackasotarex
1 year ago
Thank you so much!
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@aniketdas7803
1 year ago
Just wonderful ❤️🔥🔥
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@Classyangelic
4 years ago
thank you! This has supported my learning!
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@trainerbrock2428
3 years ago
Videos like this are the future of molecular biology education at all levels. Great video!!
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@gyurendakke1984
4 years ago
God, the ETC always confused me, but this amazing video made it so clear. Thank you.
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@frida1658
1 year ago
what are the purple things at 6:35 please help I have a midterm on Friday and it is sending me into cardiac arrest not knowing what those purple structures in complex 4 are
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@yadavkomal
1 year ago
Thank youuuuuu.... Understood it in its entirety for tye first timeeeeee😮😮😮😮😮😮🙏🏼🩷
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@genathaimed2828
2 years ago
beautiful video :)
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@behayluyibe7652
2 years ago
Thank you very much I feel your effort
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@BPLeroyLotusEvora
4 years ago
Absolutely fantastic educational video about the mechanisms of mitochondrial energy production!
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@tomorourke6301
3 years ago
Since I've gotten Clean and Sober, this has become my all-time favorite video...feels like a Plato's mystery school subset....
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@diyaroy7187
2 years ago
Owo that's amazing. I am a new visited of this channel. But I'm love with it
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@lukaschumchal1001
4 years ago
Just amazing and very usefull animation . Thank you.
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@kalldr6355
2 years ago
Thank you so much for this, you're saving lives out here
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@UpdateTV2448
11 months ago
Outstanding
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@feliscatus4921
4 years ago
This is so useful! Thank you:)
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@viniciusbenine7063
2 years ago
I've learned so much watching on this video than my whole school life.
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@paulakandjeke9576
3 years ago
Thank very for explanation
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@carlopersonal
1 day ago
Estan mal nombrados los complejos. EL complejo 1 aparece como 2., el dos, no puede bombear directamente protones al otro lado de la membrana, y es el de color verde
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@SoirEkim
4 years ago
I may not be fully aware of what it took to put this information together. Yet, I love learning in this way and the visuals are mesmerizing. Therefore I would willingly watch several days worth of videos like this. Excellent! Thank you.
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@explorenature8802
3 years ago
Very fruitful.Thank u
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@hemo2458
1 year ago
This is very fantastic
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@swnerd-2320
1 month ago
I have a biology degree and am here to refresh my memory of these important concepts. Thank you!
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1 reply
@sweetpea7270
2 years ago
incredibly helpful, and great animations, THANK YOU SO MUCH
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@phatpoint
2 years ago
Nice video!
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@markie9739
3 years ago
Simply WOW, thank you so much for this video!
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@sarafernandezfuente5168
4 years ago
it helped me to understand better this proccess that sometimes is hard to memorize!
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@aurora2319
3 years ago
AMAZING clear and understandable video!
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@maazullah5492
2 years ago
very helpful video ☺️ ❤️
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@mattphorwich
3 years ago
Great video! Such a majestic amazing process!
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@uroojrajaakram3079
1 year ago
Thanks a lot ❤❤
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@yverteatoko5960
3 years ago
Very good video.
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@ghulammustfa3059
2 years ago
Thank u soo much sir❤
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@vithalbhaipatel1013
2 years ago
Well show. Good information. Well.
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@leonidkerchev4256
3 years ago
Impressive! Thanks a lot for the great animation!
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@samruddhigarade2098
3 years ago
Thank u so much for this vid🙏❤
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@diwu4125
1 year ago
Amazing!
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@chrisgreen1904
2 years ago
Thanks Harvard. Great tool for learning the ETC. Bravo 👏
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@toybajan85
1 year ago
Mind blowing presentation 👍
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@yashar9844
4 years ago
what a beatiful system and amazing animation. thank you sooooo much
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@busraertas7381
3 years ago
this video is exactly what i need. thank you!!
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@mr.quietff7072
2 years ago
nice class
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@astharajput390
7 months ago
Best video 😮
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@johnal5888
4 years ago
Amazing, great work
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@noaf2278
3 years ago
is the first cell a plasmocyte ?
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@ummesulaim5949
3 years ago
This is literally the best video up there❤🙌🏻thankkk youuu so muchhhh
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@Rayoulastreet
2 years ago
this is just simply beatifull
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@nikolasortega3346
3 years ago
God this is amazing i whish i had these kind of videos when i had to studied this for my molecular biology exam
All i can say is this is pure gold
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@bikram4you
2 months ago
Thanks for the video....I finally know how oxyegen turns into water in our body
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@woocash2526
8 months ago
Wow! Just wow!
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@nsbd90now
2 years ago (edited)
I like biology and I really like modern animations of biological processes. Absolutely amazing! I subscribed.
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@tk423b
4 months ago
How do it know
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@NK-wf1bu
4 years ago
ThaNk u soo much, very helpful👌👍😊
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@catmom1322
3 years ago
This is terrific! I wish we had had something like this when I was i n grad school, but I'm thinking some of this may have been discovered after I graduated. Either way, I'm loving this!
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@杨涛-r4q
1 year ago
really useful for students studying Cell Biology, lots of thanks.
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@Nani...nandagore
1 year ago
Thank you so much🥹
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@divyanshkatara7553
1 year ago
What is flip flop movement of UQ and lateral movement of cytochrome c.
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@slehar
3 years ago
Just extraordinary at so many levels!
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@abhinabachakraborty7207
3 years ago
Dont have words to appreciate enough how beautifully this video has been made 🥰
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@spacelemur7955
2 years ago
Is it fair to assume that the different complexes that harvest electrons via different routes have all evolved separately (and even are the winning methods, less efficient alternatives having failed to compete successfully)?
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@tarka38tara34
4 years ago
amazing work !!!!!!!!
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@itssaptarshi1826
1 year ago
U just brought biology to whole another level .. hatsoff 🎉
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@bhagya2010
1 year ago
thank youu😍😍
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@septemberamyx
2 years ago
Excellent
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@melisakoruk6864
3 years ago
thank you for great explanation
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@lakshmimadhavan5448
3 years ago
Super explaining
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@the81kid
4 years ago
Nicely explained!
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@tonyarcus
1 year ago
Nice video. However, all the atp produced is inside the mitochondria, how does the rest of the cell, outside of the mitochondria get atp to do their work?
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@anonymous._._._.
4 years ago
Most amazing video
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@shuvradeepkar4349
1 year ago
Only one word : AMAZING!!
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@tiffany5333
1 year ago
Thank you
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@Brightsider1
2 years ago
What an amazing video!
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@darkmoon3646
2 years ago
This is so damn complex, thanks for the animation
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@khushboobadgujar358
3 years ago
Such as a great clear explanation
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@myatthuswe6093
3 years ago
incredibly amazing animation video helps me. thanks
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@partypao
4 years ago
Wow!! Now I've finally understand it!! Books can never explain a complex process as this!
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@melaniemansir3173
3 years ago
Thank you so much!! this was brilliant
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@CloudScience
2 years ago
Thank You
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@heba5835
1 year ago
Really perfect💕💕💕💕💕💕
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@charlesokeefe8788
2 months ago
I do not realize all this, but I assume law of simple machines at work. My q is if Injest protein 1 day, then next couple of days carbs or something, does that protein intake last all 3 days. I ask cuz usa diets so processsed.
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@dalmamartinovic8371
4 years ago
Outstanding animation and narrative.
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@aartisahu6182
3 years ago
Very useful thank you so much
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@michaelrowland-us3he
5 months ago (edited)
At 2.32 when he says protons are the same as hydrogen ions?
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@accaboudesair
2 years ago
Love it
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@oldsteamguy
2 years ago
breathtaking
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@Margo296
3 years ago
Finally I understood what the electron transport chain is! Thank you so much <3
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@josue25
10 months ago
Awesome🎉🎉🎉🎉
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@ruchirlawate624
2 years ago
Brilliantly clear, thank you!
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@HawthorneHillNaturePreserve
3 years ago
Excellent
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@suhaniprajapati4799
3 years ago
best video on ETS !! I finally understood it!!thank you very much!!!!!
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@sunitha4037
4 years ago
Crystal clear visual explanation ✌
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@FlashproCrazy
1 year ago
Amazing
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@chrismathewjoseph1283
3 years ago
Nice animation... Made my lyfe much easier thx❤️👍
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@zack_120
3 years ago
If added the detailed electron transfer processes at the sub-/atomic level, it would be extremely more interesting and help understand ETC.
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@wanderlustexcursion
3 years ago
Beautiful explained
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@hussainal-daheri3134
1 year ago
thank you so so so much
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@logandefreitas1416
3 years ago
this is sooooo frickin helpful
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@lorrainecamilly7354
2 years ago
É um dos melhores vídeos sobre o assunto que eu vi, muito didático. Excelente!
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@johnbates2709
3 years ago
Excellent
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@kiranmadduru9099
3 years ago
Excellent
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@imnotridaaa
2 years ago
This is all happening in every single mitochondria of my body giving me high voltage goosebumps! ⚡
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@phydonne
3 years ago
Cuando leia un libro de biologia no le entendia nada sobre la cadena de transporte de electrones. Pero con este video me parecio mas entendible aunque demasiado tarde ya que en ese entonces no sabia nada de ingles fue como hace 7 años.
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@mokshadavernekar8178
2 years ago
Wow...very nice explanation😍😍
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@rutujagore1483
4 years ago
Really suparb animation. It make visualize the things 👌🤘👍
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@martinheymogensen
3 years ago
Best illustration of the ETC I have every seen!!!!!
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@manojy5876
2 years ago
Amazing 🥂
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@shreyadas6453
4 years ago
Thanks for this vedio
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@deivasigamanisundarathatha5202
3 years ago
Wow.. Very valuable information.
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@ethqn996
10 months ago
what a beautiful world we live in. what a joy it is to be alive. how amazing is it that we are so wonderfully complex
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@sujeetpatel-hk7vh
1 year ago
Amazing
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@nithichotechongrungruang3778
4 years ago
Thank you, we're all very grateful of what you did.
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@ezyloka
1 year ago
wish i had this in school
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@pallavi07100
4 years ago
This is amazing ⭐️
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@kega4062
2 years ago
so cool!!!!
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@medicallabtech7993
4 years ago
simply amazing!!
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@abidkhan1081
3 years ago
AMAZING AND EASY TO UDERSTAND EXPLAINATION
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@hobobazaar8196
2 years ago
Great video, I have long known that the mitochondria is the powerhouse of the cell. Now I know why!
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@LalaFilmes-f8q
1 year ago
Obrigada você realmente me ajudou muito 😄
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4 years ago
Thank you so much. Greetings form a Molecular Biology Research Group (BIMAC) at Universidad del Cauca, Popayan, Colombia.
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@AZ-qx1xd
4 years ago
This is amazig! I am very thankful!!!
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@celsaprado4185
3 years ago
Thank you.
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@joshithmurthy6209
3 years ago (edited)
OMG!!! the animation is awesome !!!, I love this channel, it explained ETS in the best way.
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@gkmurthy6529
4 years ago
🙏🙏 thank you Dale muzzey sir for such a animation
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@abirbk8361
2 years ago
thank u so much sir god bless you :) <3
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@nishgupta8741
3 years ago
U taught us superb....sirr..
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@XFz2nLDWo73x95
2 years ago
I am not a biochem student.. but I will always nerd out on these videos. <3
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@dobariajalpa8680
2 years ago
Amazing
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@vioseven3799
3 years ago
Amazing!
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@ambermalik787
3 years ago
Brilliant animation, great contribution for spreading knowledge among humans, marvellous. 👍👍
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@Neet-fy9ch
4 years ago
Most amazing video ever watched
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@Beonrightside
2 years ago
thank you so much we need more videos like this which make science more understandable
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@singalongwrudy8690
1 year ago
I wish I could have SEEN this in Biology class insted of reading about it.
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@Kisyov
3 years ago
Stunning!
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@kundanr5696
4 years ago
Well i dont know anyone noticed that background music was like
We are really travelling cell world . It is great video and made my day by its music
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@rthmjohn
4 years ago
Hands down, best video on the ETC on YouTube.
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@advaitanahat2779
3 years ago
Awesome!
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@sparttin117john
2 years ago
This is a lot more interesting than what was in school.
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@rimal9305
3 years ago
this is fascinating
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@AndreasHLux
4 years ago
Wow, thats an very important answer of a question i hav had to the real-systematical DNA/RNA reduplication. Not very specific for the molecules Type, but a bone of reasoning.
Thanks a lot, ... ima pleased to watch the more others animations you made.
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@danielvillanuevaavalos
2 years ago
Hello. Is there a way that I can get in contact with the creators of this animation? Thank you.
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@MrAmalthejus
3 years ago
This video made me emotional
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@ad786ify
4 years ago
Thank you 👍👍
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@dominators7118
2 years ago
Wowtastic👍💕
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@saisarvam4331
3 years ago
Great sir
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@wjwjnwnjwjw
2 years ago
Best one💥
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@iloveamerica1966
4 years ago
That was awesome!
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1 reply
@CaptainSteve777
8 months ago
It all looks like an elegant design to me. ;)
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@GrixM
6 months ago
Are all the complexes necessary? If so, why? Why do we need to breathe if only complex IV requires oxygen, cannot complex I and III just do the pumping instead?
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@nggmodding7111
8 months ago
nice
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@jimibb4216
4 years ago
thank you
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@timofeybobakov3628
3 years ago
Okay, so if the Complex I uses energy liberated from electron jumps between redox centers, that energy is used to pump protons.
But, Complex II does not use that energy to pump protons. So, where then does this energy go? My guess, Into jumpstarting the movement of Coenzyme Q , maybe?
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@jupitereuropa-e3w
4 years ago
I want more animated videos like these!
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@burhanbashir4950
2 years ago
Thank u
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@yleniamafodda9347
1 year ago
beautiful metabolism
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@mahparariaz4965
2 years ago
Fantastic the best in biology
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@tomhorseman9832
3 years ago
I knownthis is viewed as "boring lecture crap" but this stuff fascinates me so much. And I absolutely love it. I went to college for this shit but had to leave during my last semester.
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@vanessah4943
4 years ago
AMAZING!
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@vipl7025
3 years ago
Wonderful
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@probability_density
3 years ago
Videos like these showed me the astonishing complexity present in our lives. I have never gone back to my old way of viewing the world since those formative adolescent years.
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1 reply
@sonalisonar2333
3 years ago (edited)
Just .. incredible keep doing more videos from 🇮🇳
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@sidclark1953
3 years ago
Phenomenal!
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@faisalkhanlucky2732
3 years ago
Best explanation ❤️
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@mariovelez578
4 years ago
I just like seeing these animations
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@dvuono1
3 years ago
Complex I and II are mislabeled in this animation. Complex I is the transmembrane protein (labeled complex II in the video).
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@ameliabarrett8805
2 years ago
I never expected to be learning this much biochemistry in my Bio 101 college class but...here I am. Thank god for this video!
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@naikrosh
2 years ago
Awesome
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@1.4142
1 year ago
If all courses were like this we would have world peace.
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@marcorozo9922
3 years ago
How they remove protons from the atom's nucleus isn't it bound by strong nucleus force?
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@ronaldagnes2269
3 years ago
De are wonderfully MADE...
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@nunodfes2
3 years ago
Very well explained. Great work. I wish this existed when i had my biology degree back in my University years lol. At the time this seemed much harder to understand than it actually is
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1 reply
@atmanbrahman1872
3 years ago
Marvelous design.
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@Snm-y5o
3 years ago
Great got it !
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@عبدالوهابالطلى
3 months ago
And some deny the intelligence and power behind all this truly admirable demonstration of power and art exhibition from nanoscales to gigascales can't be without creator
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1 reply
@ritisha9865
3 years ago
Didn't understand very clearly but video was amazing 👍
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@shahparwar272
1 year ago
PERFECT
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@mohamedhegazy2139
4 years ago
Wonderful....
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@nusratjahan4922
3 years ago
Thank u ......
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@ashoksonawane5050
3 years ago
Lovely video @from great India
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@yuunishinoya439
3 years ago
thank youu
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@mafazabatool5234
3 years ago
This is making me feel alive... Omg this video is mind blowing 🔥
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@maajidsyed2847
11 months ago (edited)
4:35 Energy is harvested by complex I to pump protons.
what is the form of energy released by an electron moving through the redox centers of complex? and how is it used to pump protons. What happen to the proteins that they start pumping protons? Anyone
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@alejandrotorres1191
3 years ago
OMG!! THIS IS THE BEST ANIMATED VIDEO!!
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@laylachemist5245
4 years ago
Well done
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@rovatogger
4 years ago
Amazing
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@12Monkeysable
4 years ago
Thanks a lot. I use it in german "Higschool" for my students.
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@sl5311
4 years ago
This is extraordinary.
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@juzy1022
4 years ago
this video is blowing my mind away
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@ghaznawi143
1 year ago
loved (💜)
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@glud2292
3 years ago
めちゃくちゃ良い動画
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@สมชายอิ่มโพธิ์-ท6ช
2 years ago
ขอบคุณ
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@livefortheweekend420
3 years ago
Great animations. A little bit out of my realm of understanding but interesting and informative nonetheless
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@pawerymut9033
2 years ago
Your prononounciation od word organells, with The accent on The middle syllabe is so strange and unnatural that i cant listen to this, it gives me goosebumps.
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@hectorhugoariasvasquez8632
4 years ago
Por favor podrían activar los subtítulos en español ?
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@subhashranjan3722
3 years ago
Awesome
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@michel.b5752
4 years ago
So molecule entering complex I release 2 electrons, and become charged twice. What do they turn into ? They cannot stay charged for ever.
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1 reply
@MuhammadSaeed-ym5qr
1 year ago
Great
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@dlu0813
3 years ago
The simulations for the phospholipid bilayer at 0:45 are SO cool! 😄
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1 reply
@andrebonneau9919
2 years ago
I'm a physician with a bachelor's in biochemistry. Great images to transmit knowledge not just electrons.
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@RariaRoyal
6 months ago
Meow wolf in Denver sent me here for some reason!
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@SarimaWrites
1 year ago
We're offering this course this semester
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@hectorhugoariasvasquez8632
4 years ago
Excelente.
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@Cafecortao
4 years ago
so niceeeeee
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@musaritrashid2517
3 years ago
Nice
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@memogap88
2 years ago
Also complex II does NOT use Energy Liberated to Pump Protons. Is Energy HEAT and if so what regulates the HEAT if not used ie. dissipates without causing adverse - unintended altering effects?
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@taslim3650
4 years ago
Respect to who contributed to make this Amazing video
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@Stamnessj
9 months ago
How would changes in cell membrane fluidity and permeability affect this process? If monogastric animals, such as humans, increase intake of omega-6 polyunsaturated fatty acids, it will change both fluidity and permeability of cell membranes. This video made my head go into high gear.
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@balapuramchalapathy4029
1 year ago
beautiful
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@viraatsgaming5369
1 month ago
Wow...
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@quotidien_
3 years ago
How can free protons exist in both the matrix and the intercellular membrane? Wouldn't the protons bind to the water molecules to form H3O+?
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@calixtomelo1213
4 years ago
Simplesmente extraordinário! ❤️❤️💎💎👏👏❤️💎💎❤️❤️❤️
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@blobi.
2 years ago
beautiful
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@SecondShiftPleb
3 years ago
What form does the proton come in? Is it a stand-alone proton (i.e., hydrogen without any electrons), or does it come in the form of any positively charged atom? (probably hydrogen)
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1 reply
@christianherdt2932
3 years ago
Großartig, ich bin begeistert. Best wishes from Germany!
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@UTtherapy
3 years ago
I almost couldn’t keep up!
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@eddybobea6709
3 years ago
Simplemente impresionante.
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@macrofage1551
4 years ago
Nature is fabulously complex and stunning at any scale.
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@Hiteshshlaki
3 years ago
What an animation!!....This should win Oscar
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@bertdog7639
3 years ago
It is amazing to me that we can figure these things out. The real question is, are we really sure that this is how things work?
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@Captain.Mystic
2 years ago
It feels wierd for it to click that the protons are pumped through the chain because of normal electromagnetic rules on a tiny scale like this. The redux centers are literally an atom thin wire being an inductor(think a powered copper wire) for protons to be attracted to like a magnet.
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@nihalrasheed9827
4 years ago
So one question, FADH2 doesn't use energy to pump protons... So where does it go?
Also how is Complex 3 pumping protons?
Incredible video sir! Absolutely phenomenal how clear it made this process to me . I can finally appreciate how magnificent our body is and the importance of each point we study now I know how it all works , Bravo
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1 reply
@hashrafi7148
4 years ago
does anyone know how to make a biological animation like this?
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@NaduaGarbe
2 years ago
Meu Deus, que coisa fantástica.....!!!
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@harrrytoool1391
3 years ago (edited)
This is a brilliant explanation of the energy creating process. There’s only one confusing.com part. In Protein complex 3 and 4 the colour of the hydrogen atom in the water molecule and the proton atom are the same. Correct me if I’m wrong as I need to understand, I guess we need oxygen to mop up free radical electrons which steal electrons from genes and other molecules therefore stealing other molecules and genes functionality. Fascinating.
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@harshitharajshekar2234
3 years ago
No one Can't beet this kind of explanation 👌👌
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@ترميمالحياة
3 years ago
الا يوجد ترجمة؟
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@melissarainchild
4 years ago (edited)
Thanks for posting, now... I "get it"...
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@c00lguy94_
2 years ago
Cool visualization, looks really weird and detailed
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@kiranbhardwaj9167
4 years ago
Understood!
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@austindolan3142
2 years ago
Im taking biology right now, and after learning about cellular respiration I watched about this, I wish I had seen this before taking that test lol
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@SB5SimulationsFerroviairesEEP
3 years ago
Merci de l'échange! Très intéressant! Stéph.
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@tombenson5957
1 year ago (edited)
What an amazing video. Just imagine, every mitochondria has zillions of molecular crankshafts, spinning away generating power, and you have 100 Quadrillion mitochondria more or less in your body.
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@paulcarne2892
7 months ago
And this all happened by chance given enough time! I doubt very much that anything this complicated could assemble itself, no matter how much time. This is an example of exquisite engineering of the highest order.
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@issakhan100
4 years ago
Great animation! but Complex 1 should be penetrating the lipid by layer fully, while complex 2 penetrates only mid way.
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@memogap88
2 years ago
AT MIN 4.27 : A SMALL AMOUNT OF ENERGY IS RELEASED AND IS HARNESSED ? this needs to be elaborated on with possible an addition clip doing further explanation??
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@nosegrindv4951
4 years ago
Truely we are fearfully and wonderfully made!
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@MrSlovanprofessor
4 years ago
Great video crazy music - drives me nuts -
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@kaushamvisingh114
4 years ago
👏👏👏👏👏👏👏woooowww best video of ets may god give u more success
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@tacitozetticci9308
2 years ago
How about anaerobic bacteria?
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@milicejunior2203
1 year ago
Eu me rendo... Tecnologia de ponta. Whau ! ! ! !
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@hellohellogoodbye9327
2 years ago
I wish our hod Mam is like you.. U r so beautiful mam I understand this topic very easily 😇🤗
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@KM-fl5jq
3 years ago
So, in the Complex 4 oxygen is converted to water not other way around?!
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@ghostaka7405
2 years ago
woaah💯
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@Minalkra
3 years ago
I'm not a biochemist. I'm a mail clerk.
And yet here I am, learning about how exactly the ATP process works and how linked it is to respiration. I mean, I KNEW it was linked to respiration at a conceptual level and all, but the specifics were never explained until now.
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@slehar
3 years ago
Wow!!!!!!
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@SunilKumar-zs5vh
2 years ago
this was in our 11 th grade biology textbook in India and it explained whole information and some additional details that s not in the video.. i was amazed to see that this topic is in bachelor degree of biochemistry too ... great .. loved the animation
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1 reply
@fierrots
3 years ago
lot of approximations here... FADH2 is boud to Complex II. Succinate is the electron donor of CII. The odixizing site of CIII is not well on the intermembrane face. etc
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@suraiyasuraiyajui5141
4 years ago
Good
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@reshmavats8970
4 years ago
Thanks
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@marianas.1315
3 months ago
girlllllllME ENCANTÓ
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@gustavolamounier1224
3 years ago
Poderia ter alguma legenda
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@zaenaschannel
1 year ago
absolutely bkasted and watching this video happy halloween-eve
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@reahthorolund8373
1 year ago
I wouldn't usually swear on a channel or video like this, but that... was fucking insane, and fantastic. Wow.
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@ricardodm4999
1 year ago
Que alguien lo traduzca, ¡por favor!
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@NeogreenPeaches
2 years ago
How does the NADH end up in complex 1? Or is there so much NADH just randomly zipping around that it accidentally finds its way in?
Also how does Coenzyme Q move?
These questions apply to each of the complexes for their respective inputs and outputs.
Also in complex 1, do the protons get attracted to the green blob shown because it is high energy? What is the mechanism that pulls them in and forces them to the other side of the grid?
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2 replies
@timothyborys916
1 year ago
In complex-4, so water is one oxygen and 2 electrons? There should be 2 hydrogen molecules and 1 oxygen to make water. Can someone explain?
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@NeonsStyleHD
2 years ago
Fascinating. Makes you wonder how life came up with this in the first place. It all seems to depend on each other.
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1 reply
@neuronneuron3645
2 years ago
How does the system detect a lack of a protein gradient
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1 reply
@ciafoxyloxy
2 years ago
are mitochondria organelles ?
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@Richard_Ashton
2 years ago
If I'd only had this when I was doing my degree paper of Aerobacter Aerogenes back in the early 70s. So before computers it was so hard.
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3 replies
@jengoweekes2841
4 years ago
H+ ions moving due to concentration gradient, biochemistry is so cool
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@thebest9791
2 years ago
Where the duty of heme iron here?
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@thomascorbett2936
3 years ago
The things that mankind is able to figure out understand is the most amazing thing to me .
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@crenapun57
3 years ago
Tq
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@tracycampbell9300
2 years ago
Wow.
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@evenhauge5579
1 year ago
Didn't expect Gus Fring to help me with biochem
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@MrAmalthejus
3 years ago
It is incredible to think that such systems evolved on their own.
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1 reply
@leifharmsen
1 year ago (edited)
Imagine I've lived for 55 years with all this going on and didn't even know about it. What was I thinking; that it was magic? You'd think people would be deadly curious about how it all worked until they figured it out. Oh, that's what you're doing. Bravo!
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@fantaxtick9482
2 years ago
The most amazing thing about this is that all this came into being all by itself. Wow
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4 replies
@DavidStruveDesigns
2 years ago (edited)
I love this video! It amazes me that inside every cell of our bodies we have what essentially is hydro-electric dams complete with turbines that enable our cells to do work - albeit using the controlled flow of protons in place of the flow of water. Yet again, nature beat us to the punch when it came to invention! Funny how we came up with the exact same solution to our power needs with NO idea we already had the same design hidden deep within ourselves.
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1 reply
@Cup_of_tea424
3 years ago
that was... amazing. just imagine how HUGE this is... like... hundreds of these power plants for each part of the mitochondria... and then that means each cell in the human body with a mitochondria can do this ... each cycle produces 32 atp.... IN EACH CELL... and those power our whole body!
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@lauram9478
1 year ago
❤
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@DanielleAdamstranspride
1 year ago
I wonder why I can't get hit with browser hijacks for things like this and basics to Calculus and other things that will help me through college.
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@alessiatoma4556
7 months ago
GOD BLESS YOU
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@majidrahmani204
1 year ago
👍👍👍
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@DaeZey
3 years ago
Can anyone tell/point me to a video explaining how complex I uses the energy from the redox centres to pump protons?
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1 reply
@juliannak2771
2 years ago
💙
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@arjunharikumar9040
2 years ago
So if O2 absent then the electrons get accumulayed in complex IV?
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1 reply
@imnotridaaa
2 years ago
Woahhhhhh!
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@Muslim_5566
1 year ago
I appreciate your animation but 1 mistake I see in it that the complex 2 actually is an extrinsic protein, but in your video it is shown as intrinsic protein, which means that,
It is not through-and-through to the inner membrane, it is only attached to the inner side.
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@smiggyballs4100
1 year ago
does cyanide toxicity come from affecting this proton gradient? i cant find anything in plain english but i remember learning that cyanide works by shutting down mitochondrial activity
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2 replies
@its8484
3 years ago
❤
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@rosilenerebeca5623
2 years ago (edited)
There are a mistake about F0 protein. Is FO (letter o) protein due your inhibition by oligomycin and therefore is not Fzero.
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@-eu3xx
1 year ago
Being a neet aspirant i loved it.
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@mosaddekahmed8550
2 years ago
অনেক ভালো লাগল
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@laviniaminotti4548
2 years ago
😍😍😍😍
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@4E414D45h
2 years ago
This factorio run is crazy
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@slee9838
3 years ago
Waoww
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@পাঁচমিশালি-দ৭র
2 years ago
🤩🤩
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@unhombrealado
8 months ago
It’s incredible what happens in trillion of our cells, and it’s even more astonishing that we’ve been able to gain this level of understanding of what goes on. Wow
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@blazednlovinit
4 years ago
In the UK we have replaced the mitochondria in a fetus of a mother with a mitochondrial disease before, creating the first human made from the DNA of 3 people (1 being only mitochondrial DNA, but still)
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@bingpengyan2375
2 years ago
It will be better if could have subtitles since my English listening isn’t not so good
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@12fold
1 year ago
Project Orion used pop bottling tech and so does the ATP molecule.
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@boson2916
2 years ago
Amazing! It's less than a microsecond's job begins with the breathing.
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@ThatOpalGuy
1 year ago
utterly astouding.
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@stockmarket2041
2 months ago
Hard to believe 😮
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@chrisly2775
3 years ago
This is so cool. This is why I'm going to be a medical illustrator.
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@CodNinja33
2 years ago
Really makes me miss Rob Lue 😢
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@ayeshasiddiqha3250
6 months ago
Hi there, I have taken biochemistry as my major (without researching about it). I don't know what to do next. Can anybody help me........ Know To what........scope ......and will be demand for jobs in future.
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@stephenarmiger8343
2 years ago
It would be amazing if we humans could both teleport and shrink our bodies wearing a cellsuit , rather like a spacesuit , and explore the cellular universe.
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@diptirajput7881
4 years ago
Wao
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@sam.asdfjkl
2 years ago
Hats off to the creator 👏🏻👏🏻
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@brianadams5996
4 years ago
When i was in school atp had just been discovered. I wonder if cells look different depending on the food we eat. Glyphosate or roundup is dangerous to humans.
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1 reply
@marchelandersen6839
2 years ago
i like this. oxygen turn intoo water can your body also split water if it can how does it do it ? i love this.
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@marinaquintinosilva.
3 years ago
💚❤💚❤💚
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@Potatomatoo
3 years ago
Dammmm
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@triducle9527
8 months ago
wow life is amazing
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@preciouse
4 years ago
the body is amazing
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@AlanCostaPlus
5 months ago
Can't believe this is only ad based content and that it is already 6 years old
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@Pablooov
2 years ago
perfect visual of "The mitochondria is the powerhouse of the cell"
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@martahernandez6034
3 years ago
interesting
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@josecardenas8334
3 years ago
7:10 looks very similar to tree/fungal structures on Mother Earth, but just digitized and defragmented.
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@إيناسموسىبوبيري
1 year ago
What is the end product from this process?
Water or oxygen????
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@omsingharjit
4 years ago
How can bare protons exists just by chemical reactions ?
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2 replies
@samuelthomasperkins
3 years ago
For a popular science book that delves into the history and present (as of 2015) state of knowledge for cellular bioenergetics, check out The Vital Question by Nick Lane.
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@omsingharjit
4 years ago (edited)
Who engineer such mechanism
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1 reply
@MostlyPennyCat
4 months ago
How come those protons, hydrogen nuclei desperate for an electron, don't tear everything around them apart?
I would have thought all that charged atomic hydrogen would rip electrons of anything it got near.
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@jeendabhagat1670
2 years ago
exterimely excullent
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@atharvamathapati8259
3 years ago
👍🏻👍🏻👍🏻❤️❤️❤️❤️🔥🔥🔥🔥🔥
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@pumpkinwizard9080
1 year ago
So you are saying Mitochondria is not a completo?
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@codrut913
2 years ago
<3 !
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@theunique880
2 years ago
🌈😍
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@ruki25
3 years ago
When they said Mitochondria is the powerhouse of the cell, I didn't think it was literally powered by the flow of something spinning what is essentially a turbine of sorts
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@anonim5052
2 years ago
Mitochondria is a powerhouse of a cell
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@eselseptimo
1 month ago
La vida
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@Dude_Its_Michael
1 year ago
at 1:00 it says the intermembrane space has more protons than the matrix but shouldn't that be the other way around, Don't they move from the maxtrix into the space.
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1 reply
@jdogcisco1
4 years ago
Hard to believe some chemicals just happen to get together to make amino acids that get together to make proteins that get together to make structures that have such intricate processes like this that are necessary for yet a larger structure to 'survive', which are yet still part of a larger organism that figures all this stuff out. Mind blowing.
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1 reply
@زهراء-ر6ر2ش
5 months ago
its very easy
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@raulmartin1864
3 years ago
It is not F0 but FO, because of its Oligomicyn sensitivity.
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@terrihenges8743
1 year ago
I am not a scientist but have been learning about nutrition and it seems at the heart of all metabolic processes the optimal functioning of our mitochondria is the key to good health. Our Western processed food diet is the reason our mitochondria, and we as a society, are sick.
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@χρηστοςΜπακολουκας
3 years ago
!!
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@vaishuupare099
1 month ago
3:30 : wow
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@gurammanjavidze6150
3 years ago (edited)
i still didn't understand why don't all electrons go into intermembrane space and form water moleculs?
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@patldennis
3 years ago (edited)
My suspicion is that aerobic metabolism started out as a means of detoxifying the oxygen pollutant that photosynthetic organisms were pumping into the atmosphere and it was eventually coopted through evolution as a means of producing ATP.
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@zahraan5070
3 years ago
wow very simple
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@lucasatsuo123456
3 years ago
Oh yes, the powerhouse of the cell
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@flavaa9494
3 years ago
once again youtube saved my life
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@leom091
3 years ago
Videardo!
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@ilimselyardm9698
3 years ago
MashAllah , SubhanAllah thanks great video may Allah bless you
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@yogeshchaudhary5821
1 year ago
Best best best
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@anaghanair3387
3 years ago
This made me feel ALIVE
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@emil.jansson
4 years ago
🤟🏻
1
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@yame8134
4 years ago
モーターの回転数は負荷が軽ければ1分間に10000回
電ノコは1分間で1400回転とか。やべぇよ
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@snakesandsticks
2 years ago
Where was this when I was an undergrad? 😩
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@m3nt4l173
2 years ago
Mitochondria is indeed the powerhouse of the cell.
1
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@blazednlovinit
4 years ago
ATP is a fascinating molecule in the way our biology uses it. It's like a nice little prepackaged battery ready to go :)
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1 reply
@dogchaser520
2 years ago
I think it's kicking in
1
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@Mohammed347AA
1 year ago
تحية من كلية مزايا الى جامعة هارفرد ، بوساتي 😘
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@DanielleAdamstranspride
1 year ago
Mew mew needs a lot of help with cellular respiration and genetics. Hope I pass the class too.
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@graynephalim
3 years ago
How the hell did this end up on my feed?!
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1 reply
@motalabhossan381
3 years ago
This is real education
1
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@sachielguluma5519
1 year ago
i don't even do anything biology related, this is just interesting.
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@jacoblikestodab
4 months ago
I’m at meow wolf and there was a url on the wall I’m on acid and this is what popped up
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@chromebaby
2 years ago
I can comprehend how evolution produced the variety of animal and plant shapes there are. I can even comprehend how eyes and flowers that mimic the shapes of insects evolved. I can also just about get my head around how cells evolved – barely though. But I can’t begin to fathom how any of this got going. What were the stages before what’s happening in our mitochondria now? How did all those protein shapes come about? And their behaviours? It’s utterly insane what’s happening here.
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@malkeus6487
2 years ago
You were so close to meme territory with that power plant comment.
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@widescreen8964
2 years ago
Where do these protons come from?
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1 reply
@jupitereuropa-e3w
4 years ago
Well societys of any kind are like cells to, working hand in hand to grand reproduction, energy gathering, protection and many other tasks.
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3 replies
@youtubestop3346
1 year ago (edited)
Its weird to think that even our bodies use what is essentially a spinning wheel to generate energy like we do in power plants. It really shows how we love to mimic nature even unknowingly sometimes
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@jan_phd
3 years ago
When you say GIANT cellular powerplant... what is the scale of that?
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@rickastleyrule3497
1 year ago (edited)
We live in a day and age where top educational institutions offer courses available to the public for free, anyone from the us to Pakistan can simply search a topic up and study away truly the advent of technology is nothing short of a miracle
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@РамильТатарин-о7з
3 years ago
5
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@josepiratilla
7 months ago
I can’t avoid feeling like seeing the teaser trailer of Factorio II.
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@karkleswhitevans
1 year ago
Gustavo Fring found his new calling in cellular biology.
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@eatandrepeatt
4 years ago (edited)
Thank you so much Sir
This video is amazingly epic....
Pls keep uploading that type of videos for us...... Thankful......🇮🇳🇮🇳
1
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@HealthyThinkingsubstack
5 months ago
This is quite excellent but it should’ve been better. If this was produced six years ago in 2018, then they should’ve included mention of supercomplexes. If they wanted to go farther, they could’ve talked about nutrition in more detail.
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@mjproebstle
3 years ago
this is insane in the membrane!
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@fredrick443
4 years ago
Haha. How dare you put this in my feed, YouTube! I get enough of this at school!
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@s.abirami8394
2 years ago (edited)
Small process in tiny organelles we can't able to see that naked eye .....precised And does the work perfectly. It's hard to beleive that all these things takes place in our body it's wonder thing but this the proof that human beings are alive today 🥺
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@PookieAndAnnie
2 months ago
This was posted 6 years ago😮
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@juansantana6307
2 years ago
How do we figured this shit out in the first place tho
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@davidtompkins5000
2 years ago
We are wonderfully made.
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@Vibycko
2 years ago
So you are telling me, that mitochondria have a firetrucking turbine to create atp!?
1
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@kukunishad
1 year ago
It's really mind-boggling that, how we know this mechanism at atomic level??!!
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@tomoakhill8825
4 years ago
At 6:50 "the reason we breath oxygen is so it can be the final acceptor of
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@belginruzgar6130
2 years ago
Nuray Akkaya Zonuz hocamız Türkçeye çevirdi. Ben buradaki videoya ekleyemedim.
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@drewfisher1619
4 years ago
To consider that these sophisticated machinery works in our body without us even thinking.
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@edavivia
3 years ago
If you calculate the number of protons in using the size of mitochondria at physiological pH, you would know there are approx. 10 protons within a mitochondrion. There are millions of these respiratory protein complexes which are purported to "pump protons". Oxygen is very diffusible and hence the idea that it would be present solely at Complex IV to make water without any interaction with other protein complexes seems too deterministic of a scheme to happen under normal physiological conditions. Also, the whole scheme of pumping out protons to generate a TMP in the intermembrane space while assuming that the outer membrane is impermeable only to protons while allowing much bigger atoms through also seems unlikely. The whole scheme has also been shown to be thermodynamically unfeasible by recent publications. It is high time we look beyond chemiosmosis, electron transport chain and rotary ATP synthesis.
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@lias57
4 years ago
Intelligenz Design, fabelhaft.
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@adelabrouchy
1 year ago
And all this wonder for us to be able to be alive and discussing about life in Internet. 🌻🌻🌷🌷🍀🍀🌼🌼🌳🌳
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@WaterproofSoap
3 years ago
Imagine building a progressively complex video game model based off of this animation and making it available to children
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@davipervenom9151
4 years ago
It’s difficult to comprehend that all this complexity happened by mere chance.
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@МатвейДанатов
2 years ago
мудрость
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@cheeseburger7925
1 year ago
sounds like gustavo fring teaching about cellular respiration
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@persiancarpet5234
2 years ago
Eating and breathing while watching this video in order to keep these processes going!
1
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@cynthia6514
2 years ago
Oxidative phosphorylation
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@gregorysagegreene
1 year ago (edited)
It strikes me that there's a cobbling together of various gradually-improved energy-harvesting paradigms, all to supercharge the gradient, with oxygen being the latest enhancement. And again, ATP synthesis gets better with each newer step, until you finally have that torrential gradient driving that sophisticated synthase to get the hyper-production of ATP required to support eukaryotes. One wonders if a technological redesign might be simpler, more efficient, and open up vast new possibilities for life than 3.8 by of competition for energy capture. We could have a new super species, and dramatically increased industrial power too.
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@babinomrabti5019
4 years ago
thanks mom for giving me the chance to get mitochondrias
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@JJ-qd8ek
3 years ago (edited)
I was like "what is this electron transport chain about",
then I was like 🤯
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@Safar_Galimzyanov
4 years ago
At first I thought this was SovietWomble`s video
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@alexanderpushkin9160
4 years ago
Insane.
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@defeatSpace
2 years ago
They're like specialized little computers that all maintain one organism.
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@joseramonpradorickemberg7655
3 years ago (edited)
Execelente la presentacion, podrian traducirla al español latino, somos subdesarrolados pero nos interesa la ciencia, de lo contrario no la suban al youtube.
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@zafran156
2 years ago
ok!
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@mikasaackerman-u4n
3 months ago
MITOCHONDRIA IS THE POWER HOUSE OF CELL . now i know well
1
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@pecador_tor
4 years ago
evolution sure does go a long way huh :O
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@Geekyavi1
2 years ago
2 times the data showed in this video is in MY class 12 Biology Book in India in only 1 page.
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@LuaanTi
2 years ago
Just a small thing - it's F O, not F zero. Yes, it's a bit confusing with the other subunit being F 1 :D
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@benitocarmelo4296
3 years ago
tuve un profe de biologia que le dijo a un amigo mio que si seguia encorvandose terminaria con forma de fosfolipido. ahora cada vez que veo algo relacionado con membranas celulares pienso en el xd
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@CurlBro15
3 years ago
When you think about the laws governing the quantum fields in this interaction, and the complexity of those laws, it’s beyond insane to think that all of this is really happening inside our bodies!
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3 replies
@santiagos4290
2 years ago
epic
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@pabletediaz
4 years ago
Life is a natural miracle.
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@severest75
3 years ago
Great video! Aweinspiring.Does anybody else think it's kind of hard to imagine that all these complex mechanisms came into existence just by unguided, random and blind processes?
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@Jequetepeq
1 year ago
ATP synthase my beloved
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@shanrafnezden7958
3 years ago
I fucking love science!
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@edsonborba5299
2 years ago
Infelizmente não consegui entender não sei falar inglês é uma pena
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@bitterlemonboy
1 year ago
the mitochondria is the powerhouse of the cell
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@awsomedude1011000
2 years ago
There was a QR code in a meow wolf and it brought me to this video.
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@prestonburton8504
9 months ago
where do the 'proton's come from? I know they are simply hydrogen that has the electron removed. They must be from water but how does our amazing systems break down the water molecule (which is so hard to do) to release the hydrogen atom. Then how does this electron get stripped? anyone?
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1 reply
@dimitriosdesmos4699
3 years ago
I used to be good at this !!!!
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@robertzeurunkl8401
3 years ago
4:05 - What is being described here is literally a lightning strike - following the path of least resistance - made up of individual electrons. Microscopic cellular lightning. Now you see how we are parts of a larger organism, following the same pattern on a larger scale. And, probably, our entire planet itself also part of the same continuum on a galactic scale. It's all one life form from the entire universe, down to individual atoms, and probably even deeper than that, if we could look that deep.
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@christopherleubner6633
1 year ago
Inagine the incredible possibilities if someone could hack this molecular machinery to synthesize complex organic molecules super efficiently. 😲
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@montanawildhack2760
1 year ago
holy fuck
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@nuibui6667
2 years ago
It is weird how what is taught to people in the west in biochem courses is taught to us in India in schools. Great video btw.
1
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@Athenoi33
5 months ago
In my head is like "how can it not be a higher intelligence that made these complex network of parts inside other parts?!"
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@Trathaal
2 years ago
Mitochondria gameplay: haha powerhouse boi
Mitochondria Lore:
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@CDClock
3 years ago
is that jules pierre mao
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@AB-if8pd
2 years ago
Knowing all these information and their relations to each other, has anyone even tried to make one mitochondria anywhere?
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@FAGUNIAGAMING
1 year ago
Why do we have more information than a Harvard video in our class 12 book 😭
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@idegteke
2 years ago
This makes me think that a living cell is literally full of procedures that could no way be developed evolutionarily (using successive approximation by lucky strikes) simply because they have never had the chance to genetically compete with their somewhat less functional counterparts, given the fact that their ability to function is either 0% or 100% depending on whether the genetic code that shaped them from scratch created them the exact way they should be position to function or not.
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1 reply
@devdalwadi31
3 years ago
I still do not understand why we learnt photosynthesis before cellular respiration
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@Sara-md8nu
2 years ago
Having taken 4 biology classes in the last 2 years, I literally forgot everything and cellular respiration... hah! I'll never understand that
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@cristejada1186
3 months ago
So in other words we have atomic power plants built into our own biology?
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@claudias895
2 years ago
I just scanned this QR code in Meow Wolf Denver
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@miguelcalvo2541
1 year ago
The mitochondria is the powerhouse of the cell
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@AClarke2007
3 years ago
And the whole Plant and Animal species living in a thin membrane on the surface of a Planet too.
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@germgoblin5313
1 month ago
Am I the only one who feels existential dread watching this?
1
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@wyopoksfan
1 year ago
a QR code in a Meow Wolf took me here
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@radwizard
2 years ago
Wow, a current.
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@zbigniew2628
3 years ago
How it happend to be this way? How just from dust of start this design happend? Just trial and error method over milion of years?
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@Т1000-м1и
3 years ago
This university: hey so we ma-
Schools: no
2
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@hdhddhdb2894
2 years ago
فى حاقه
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@VoidHalo
4 months ago
How can protons exist individually within the intermembrane space (or anywhere) if it's impossible to have solvated protons. Ie free protons in solution which are not bound to any other moiety. Something is being omitted here.
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@9d8fb79fd8gb
3 years ago
RIP Rob Lue
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@kuldeepkcri
1 year ago
Our entire lives basis explained in few minutes.
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@heivmnox
4 years ago
I would never look life the same way again.. i now respect my hardworking cells. lol
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1 reply
@testsubject318no6
6 months ago
Aren't the protons in the Na atoms... or sth...
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@gangadharr3524
2 years ago
First, wanted to know how they figured this out...?
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@pinkcripps2749
2 years ago
So this is why the mitochondria is the powerhouse of the cell
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@robinsonchukwu7295
2 years ago
How do they know this... That's my question
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@firstnamelastname9918
2 years ago (edited)
fun, fun fun! So the 4th complex was taking 1 molecule of O2, 4 protons and 4 electrons to spit out 2 molecules of water in to the inter-membrane space? EDIT: Oh! the energy from oxidizing(?) the hydrogen ions is used to move 4 additional protons as well? (I'm not in biology, just a curious software engineer / information junkie)
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@kanviaery2542
3 years ago
Matrix has less no. Of protons then how these complexes can pump protons from matrix to inner membrane , shouldn't it be opposite? From membrane to matrix??
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1 reply
@mohamedalshaikh145
9 months ago
حسام عياش
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@XavierAway
3 years ago
Maybe if we could synthesise this system we can create electricity with the best possible efficiency
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@anomalyp8584
3 years ago
And then to think that this ATP generator spins like crazy. Not slow like in this animation.
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@aliietzal3687
2 years ago
سبحان الله
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@sophieodallaire476
2 years ago
How didn’t I found this video before my biology exam😭 I failed and got 48
1
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@outblufferoutbluffer2481
1 year ago
Wait,
I m fascinated by this but can't wrap my mind around it
So if an atom is the size of a soccer field the proton is a grain of sand in the middle of the field , yet here in mitochondria i see electrons and protons working so close to each other.....
Also I thought electrons are actually a cloud of probability....
I m confused
Please make me ...... just bring light !
Thank you!
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@Azavar_Kul
2 years ago
Чудо и обыденность в одном флаконе )
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@johnhoward6393
1 year ago
The molecules are sentient but extremely limited in what they can do. They are precise and super reliable. There are more things, Horatio, than are dreamt of in your philosophies.
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@Ken-rq9xr
4 months ago
There's obviously intellectual understanding of the quantum mechanics in individual cells. Where you put your eyes.😮😮🤓😽🦜👍
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@jimschiltz5343
2 years ago
My God!
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@lastyhopper2792
2 years ago
Alright, questions time:
1. Why protein complex 1 and 2 uses different byproduct of sugar metabolism (FADH and FADH 2)
2. Why complex 2 even need to exist? From this short video it seems like the complex 1 is the superior version of complex 2
I'll come up with other questions later, after I learned more stuffs
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@ashoksavlaramchoudhary3180
1 year ago
istudy this in11std respiration in plant
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@hlaakaplee
3 years ago
aww cute lil electron probability cloud probablizers
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@TheStarflight41
3 years ago
Intelligent design couldn't be more obvious.
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@ebigarella
4 months ago
The crazy broccoli carnival
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@ronaldpokatiloff5704
1 year ago
A computer must make life!!
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@Дэни-д6ю
3 years ago
rip Prof. Lue
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@drdeiceekay6865
2 years ago
I have more questions POST watching, than pre... 😅😅
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@universalflamethrower6342
3 years ago
that is abiogenesis for ya, stuff emerging from stuff
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@aysgl2666
1 year ago
i don t understand how the energy required to pump protons are collected from the flow of electrons- those green circular clouds in the complex 1 4:53
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3 replies
@Spindily
3 years ago
RIP Professor Lue
1
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@skymaster0yt
2 years ago
whaat
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@tallbillbassman
1 year ago
I believe you are missing something. This is a quantum-mechanical process, so we are looking at waves. All these structures are essentially shapes of three dimensional potential functions which guide the waves, just like a radio antenna, so that they interact in suitable ways with electrons and protons. It's not a pinball game, it's a radio show! What evolution has created is a very sophisticated version of transmitters and receivers. Biochemistry is evolved radio engineering.
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@stoichiometryc8462
10 months ago
So this is an actual video for the prestigious Harvard University... with a lower case title
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@gp235801
3 years ago
RIP Prof. Lue
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@adamc8627
2 years ago
i got my bio degree in 00...this is magic.
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@vinodunnithan1360
4 years ago
Hi
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@StrawberryBunny91
3 months ago
Anyone els scan this one at meow wolf?
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@Sickwitit18
2 years ago
Meow Wolf Denver has a wall of QR codes and one brought me here
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@idegteke
1 year ago
Whatever kind of sub-atomic particles build the atoms in this video up, they create atoms that look utterly simple and identical but, as soon as they start to meet with other atoms RANDOMLY (as we call it) and form proteins etc., they start to build structures that we can now see visualized making highly organised and unexpected things including multiplication – and, therefore, produce ideas like the one I written down in this comment. I must attribute this idea, too, to the particles that build my special atoms up to communicate this message.
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@ManyHeavens42
1 year ago
I believe through Electrons
We can cure stop Oxidation
Some kind of Electric field.
Just learned Air grounding.
That took me 2 Years. On my own. Quantum Salt year and a half.
1
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@локилоки-е7у
1 year ago
МАША ефимова ис самары я тебя люблюeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shapeeyes-pink-heart-shape
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@Istanislav1
3 years ago
мне это сносит голову
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@golammahdi1077
2 years ago
Transcendental
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@غزةستنتصريارب
2 months ago (edited)
Praise Alleh that He is all wise!.
From Yemen.
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@nancychandler768
1 year ago
And yet, my general practitioner says this is not part of her repertoire.
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@Signal6000
2 years ago
Wow thats how the energy of food and sun is used in my body. We are a universe
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@M0rquer
4 months ago
i watch this kind of video only because i like biochemistry, i don't need it yet, i am in 8th grade of school
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@oneistar6661
2 years ago
Let's speak about this perfectly tuned machine and it's origins.
1
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@leggy12
3 years ago
There is an inaccuracy in the commentary. It says NADH and FADH2 are a byproduct of sugar metabolism, whilst this is true they are also a byproduct of fatty acid metabolism, Ketone metabolism, and amino acid metabolism. In fact, at rest, we use far more fatty acids to produce these molecules than glucose.
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4 replies
@alexciocca4451
1 year ago
We are the best machines yes gotta loveit
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@dungeonkeeper42
2 months ago
I don't get it
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@robson6213
3 years ago
it makes me wonder if life is just a coincidence
1
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@celinaandrade9918
1 year ago
I knew Walter white was a chemistry teacher but I never never Gus was a biochem teacher !!!
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@Rajibuzzaman_STEM_Rajibuzzaman
11 months ago
" THAT'S WHY PSHYSICAL ACTIVITIES UND DUE INTAKES MAKES THE DIFFERENCES " A COURSE ON REJUVINATION
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@johaniswara5086
4 years ago
future study major might be "Cellular engineering"
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@jacekpiterow900
3 years ago
Hydrogen protons?
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@สมชายอิ่มโพธิ์-ท6ช
2 years ago
ตามหลักการของการชนต้องมีแรงจากการกระทำต่อวัตถุกับวัตถุครับ
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@lukehelpmetakethisdangmaskoff
3 years ago
If you are an Evolutionist, and we were hiking together in the mountains and I overturned a rock and found a paperclip, there is not the slightest chance in hell that I could convince you it came into existence by random processes. Yet you believe, that what is the subject of this video, did come about by random processes, and there is not a chance in hell of convincing you otherwise.
I find that truly bizarre and heart breaking at the same time.
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1 reply
@sahelanthropusbrensis
4 years ago
I can learn any Science but, for some reason i have a terrible time trying to understand biology. I learn it today, i can't remember tomorrow.
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@ninjamatic5000
3 years ago
how the hell did people find out about this?
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@zzz181085
2 years ago
Meow Wolf link anyone?
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@chetanpaulr
2 years ago
My God 🙏
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@WideCuriosity
8 months ago
Flabbergasted that the human race can work out/discover this level of understanding.
An interesting recommendation from YouTube.
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@mehakjan9140
1 year ago
Masha Allah 🤍
C how beautifully , amazingly, exquisitely ...Allah created everything ...
SubhanAllah🤍
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@anglesmith4840
3 years ago
This is why I believe people like Dr James Tour.
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@yaseralz3bi407
2 years ago
سبحان الخالق
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@conebread4333
1 month ago (edited)
I feel existential appreciation. No book ever wrote itself. Biology is the most complex arrangement of information. DNA for example is complex code. It CARRIES and transmits the information; but it is NOT the actual information. Just like language and math carry information. But information itself is immaterial. It’s interesting that the material world is governed by and predicated on the pre-existence of immaterial information……to me, accepting that life is a book that wrote itself and then became aware of its own existence is not satisfactory. The hurdles and holes of abiogenesis are insurmountable for the foreseen future with a materialistic attempt at the explanation of causality.
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@babacut7561
4 years ago
moin
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@vladtherussian9594
1 year ago
How in the world did you manage to know that the last Redox center in complex 1 donates exactly 2 electrons to the coenzyme Q molecule? We can barely see DNA under the microscope let alone subatomic particles. Mathematics?
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2 replies
@AndreHypnosis
1 year ago
No days off boys. We've got a body to keep running!🪖
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@PsychicLauryn
3 years ago
Meow Wolf Denver anyone?
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@mrfin1x113
2 years ago
cool i actually understand some shit now before it was like not cool
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@francoisfaure9089
2 years ago
😂😂😂
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@dy7296
1 year ago
No I'll no longer question why strands of DNA require several hundred million years to turn into prokaryotic cells and another several hundred million years for the first eukaryotic common ancestor to appear, which was theorized that sometime around 2 billion years ago, a larger prokaryote merged with a mitochondrion which used to be an independent lifeform.
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@user-sy5jb3gj2p
11 months ago
Wow, that darwin guy who called it a "simple" cell didnt know what he was talking about did he?
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@HoaLe-py5ij
1 month ago
Wow, philosophers were not wrong at all to propose biological nanoscopic machineries inside living bodies
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@BongoKotha
3 years ago
Hey a lot of views u get from our C3 mentors , and you're watchtime will increase , show some respect to C3 mentors students 🙂
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@fatihcihancelebi4613
4 years ago
Why we have to breathe for oxygen can't we reuse it?
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1 reply
@thaq8.2
1 year ago
Qhaq
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@PrankCallV1
2 years ago
dang biology are machines we wish we could build
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1 reply
@benjaminrumbewas4057
1 year ago
im hooked for several minutes till the narator hit us with "The Reason We Breathe Oxygen"
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@flewggle
3 years ago
Why would anything like this occur naturally???
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@Blankii69
2 years ago
Ratio
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@ivanbombana7282
4 years ago (edited)
How the biologists understood all of this? I don't understand...
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@yosra4365
1 year ago
سبحان الله العظيم
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@unknowngozi6386
3 years ago
So complicated
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@ObscureAudioHistory
1 month ago
Wat
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@soamazing7027
2 years ago
Great Video! (Jesimiel Millar Fernåndez) 1M937
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@pranavpatil6988
4 years ago
My textbook didnt tell me this
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@jasonmay4341
2 years ago
rip rob
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@gegeeneemns5209
2 years ago
ok
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@Voiceofmine12
1 year ago
That's fi and fo partical not f0
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@collinarter2470
2 years ago
NGL I thought this was a Worms Armageddon map at first.
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@MasterFeiFongWong
2 years ago
(By AMA) To whom it may concern.
The Key to making an over unity Electric generator work is mechanical advantage. In this case the mechanical advantage is achieved by getting the electric motor that is spinning to be able to spin a quantity of separate discs that are connected to devices that generate electrical current to generate more current then the electric motor needs to spin. One of the ways to achieve this without violating the laws of thermo dynamics is to exploit magnetic field effects. To do this you place the magnets on the disc that the electric motor is spinning in a way that makes it so while the disc is spinning around the magnetic fields are slamming upwards onto the edge of the other discs forcing them to spin, thereby generating electric current. In this way, the magnetic fields will be forced to do work that the electric motor wont be doing. This is how it's possible to achieve an Over Unity Electric generator & with this technology we can free ourselves from the use of gas. By AMA
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@PotatoMcWhiskey
2 years ago
Molecular Turbines bro wtf
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@dal2888859
3 years ago
The level of sophisticated engineering and absolute precision required for this process to go on automatically trillions of times per second for an average of 70 some years boggles the mind. To assert that this entire network of nano machines somehow pulled itself together from inorganic matter has to be the height of willful ignorance and stupidity.
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@elviscaragea4433
11 months ago
Like a machine
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@KCEPlad
1 year ago
THE MITOCHONDRIA IS THE POWERHOUSE OF THE CELL! :D
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@shashidharshettar3846
1 year ago
I’m 68 yrs old MD. I don’t know how I passed all those medical exams using just memorizing
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@MrGoat-kz1mf
3 years ago
19BOT036
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@ilkerongun3962
4 years ago
Travelling protons idea is only an approach - what really happens is the travel of an electron in the opposite direction.
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@Turboy65
2 years ago (edited)
OK, there's a lot I don't fully understand here but I know this: Free protons don't exist in cells. So it stands to reason that the protons that are flowing must be part of molecules. What molecules are the proton carriers? Hydrogen ions. So why not just say that?
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@bestelectronicmusicfromnew5189
3 years ago
that's why i prefer astrophysics and black holes. a lot easier. and... if i understood this right, we are made of psychadelic muticolor bogies?
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@kevinharte3636
9 months ago
How the hell did people figure out this stuff?!?!?!?!?!?!?!?!
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@cuatropolis2881
4 years ago
Life is simple, they said
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@mohammadmokhlis8652
2 years ago
سبحان الله الذي خلق كل شيء
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@colinwilloughby6790
3 years ago
After watching these I expect to look into my eyes in the mirror and see a little creature with a steering wheel driving 'my' body
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@สมชายอิ่มโพธิ์-ท6ช
2 years ago
และครับการโต้แย้งอาจมีบ้างแต่ทำด้วยความเครพและเพื่อให้ผู้จัดทำได้วิเคราะห์ก็เพื่อให้ได้ความจริงและน้อมร้บกับคำอธิบายพร้อมขอบคุณการนำเสนอครับ
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@grawss
2 months ago
Read the Gospel! Start with John. You become saved by confessing Jesus as your savior; that he died for your sins and was resurrected from the dead. I highly encourage you to fill the emptiness in your hearts with the love of your Creator.
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@stevenwiederholt7000
4 years ago
Remember now, all this came about random chance. Riiiight!
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@rolandovelasquez135
3 years ago
Wow. And to think that all this came about by dumb blind chance. Evolution is so intelligent!
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@laxmibhandey-oi3cl
1 year ago
Can be it in hindi
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@mikemurawski8112
3 months ago
A QR code at Meow Wolf brought me here
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@bertwesler1181
3 years ago
You do realize that when he said, "Have great affinity" that he has no idea why or what that actually means.
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@sitalin2434
4 years ago
Okay, The Human Body IS AMAZING.......
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@KanesMeridian
1 year ago
Shoutout you if you got here thru the denver meow Wolf
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@willoughby1888
1 year ago
My favorite part is how not a single word was "white", "black", "brown" and I think you get my meaning so I'll stop mentioning races, I mean colors now. This video proves we're all the same on the inside more than we are different on the outside.
Ok, I'm just a nobody 1970's 11th grade Highschool dropout with a GED who still likes to ponder things in order to keep my old man brain 'alive', so, I'm kinda wondering how much the 'more pervasive now' bacteria "Vibrio Vulnificus" would love to chomp away on all those pretty, colorful, hard-working organic items in this video. Complex I, II, III, IV could be dinner courses before all the many other desserts on the menu. Wouldn't be that complex a thing for a flesh-eating virus is what I'm thinking, even!
Um, forgive me please, I was only trying to Bee Fun Knee. Maine said to say, "Hello" for it, except for one little bitty island, but I don't think they even have an email let alone mental telepathy like the rest us on the mainland just like to use.
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@nvppatilmyhistory6733
4 years ago
Electron transport system s proton of covid 19 working which chemical compound covid 19 destroy
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@interestingcuriosity546
1 year ago
You just got to appreciate evolution and nature.I mean, an electron is the most abundant in the universe,but mostly tricky.Quantum mechanics says we cannot know both the speed and location of the electron at once.But living systems are able to even harness the energy from these very electrons! The very electrons that form the structures of atoms which make up the universe...Hmmm, weird....Just weird
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@josse4949
3 years ago
no se como llegue aquí, pero encontré diamantes ^^
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@RainAngel111
3 weeks ago
When I started to learn biochemistry, I realized how messy and well, inefficient it seemed, especially compared to artificial electronics. And it is! It's just that powering a big sack of meat without wires or strong magnets requires this kind of delicate mess. How else could it be done.
It's funny that biochemistry feels like evidence for and against an intelligent creator. It's so complex it seems impossible it could arise by chance, yet so inefficient and seemingly sloppy that it seems crazy to say an all knowing god created it
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@thochan5188
3 years ago
Is my is my mother goose club out.
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@k_catboy
2 months ago
This new Inside Out movie is weird fr
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@hdhddhdb2894
3 years ago
د.
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@ultrad-rex1389
3 years ago
Life is so complex, it's fragile...
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@balajippasumpon3333
6 months ago
Anyway mitochondria is a powerhouse of cell.😂😂
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@SidAhmedKHEROUCHE-dl8mk
6 months ago
like how can you beleive that this came out by accident .
at this moment you're just being erogant and just won't admit that you were wrong .
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@qawiyya
2 months ago
thanks MeowWolf
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@LifeOnMarzMI
4 months ago
Anyone here from Meow Wolf in Denver?
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@markmd9
3 years ago
Does this look like designed or like an accidental evolution?
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@mercster
2 years ago (edited)
It amazes me that there are those who think the idea of a creator is laughable.
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@IIrandhandleII
4 years ago
Huh?
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@islam333
3 years ago
Жаль не на русском но я все и так понял. 😉
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@DunateoRom8v37
3 years ago
Please explain this from a Darwinian evolution perspective. Go on, I'll wait.
Or
Explain this taking in to consideration irreducible complexity to illustrate pure naturalistic processes. Go on, I'll wait.
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@idlehour
2 years ago (edited)
so many inventions made by humans originally worked/are based on the concept of the many aspects of a cell's complexity. And we didn't know it at the time of inventions like turbines, fuel, movement and manipulation of electricity etc... are just stolen from evolution we couldn't see until recent times.
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@javiergarnik369
2 years ago
All universitiees nerd that
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@SubhranshuSahu07
1 year ago (edited)
I think Biochemistry all about concept and understanding
unless you make out it it is too complicated..🤦
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@UMMAT1100
7 months ago
A fully automated cellular power plant!!!. This cannot be of its own as they say all things come out of chance. This is not chance this is pure intelligence.
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@nullskull
2 years ago
Let me get this straight the mitochondria is the powerhouse of the cell ?
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@zdravkomitev9349
1 year ago
Fo not F0
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@albythegreat4648
1 year ago
It's like having tiny nuclear powerplants in your cells.
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@MikkloGames
1 year ago
Uhh I came from meow wolf and I am not qualified for this 😵💫
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@meghdaniellama1604
2 years ago
What
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@JBulsa
7 months ago
Proven to be incorrect. Electrons bond differently along the transference.
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@carmendamic77
3 years ago
.doppiato ...in italiano...no?
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@dma67111
4 years ago
And Pac-Man 1 runs to center 1 and 2. Ghosts 1&3 ...etc etc Pacman goes to center 4 and you win
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@drezilla1310
3 years ago
And people say this built itself by pure luck. WOW! God bless you all!
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@samuelkahunga5987
3 years ago (edited)
0:08 Pikachu
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@melikesehirli6042
4 months ago
Nice visuals but a ton of important details missed, video becomes actually useless.
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@Harve955
1 year ago
Hmm, sugar metabolism creating NADH. What about the alternative A Fat metabolism? Lets pretend for the sake of the Mega food conglomerates that sugar is the only metabolism contributing electrons for ATP synthase, after all our funding is almost completely dependent on the Food conglomerates.
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@machina_aeterna
4 years ago
Stardust turned into this...then into me typing this...and what would an intelligent race know after a million years? Reality is incredible, and I want nothing more than to understand it all, despite the impossibility of that happening.
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@genius6225
2 years ago
But why does it produce water in the end, we drink water all day.
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@swally1206
3 years ago
الله أكبر.
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@raplopez4258
3 years ago (edited)
7:10 The only thing he got wrong, and substantially wrong:
Mitochondria is NOT a powerplant
It IS a POWERHOUSE
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@Haveuseenmyjetpack
4 months ago
Hard to believe random mutations and environmental pressures resulted in THIS!
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@servetbozdag2359
3 years ago
We just find it out. Very well. Who did this amazing coplexity. My imagine is that comes from one and only Allah( Celle Celaluh). Appreciate for explanation
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@yinyang.333
4 years ago
That's what India yogis has said billion years ago, and advocates Yoga, Pranayama to take deep breath because more amount of oxygen will make sure more ATP generated, more ATP generation nurture body energy store and makes body healthy.
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@maxjurish2589
2 months ago
This is a good time to start believing in the genius God the creator and putting evolution in the trash can!
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@Stas_bool_bool
2 years ago
Ради одних этих видео хочется английский изучить...
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@Asdayasman
3 years ago
Abdolutely insane how all this shit is just randomly generated.
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@krose2913
2 years ago
Came here from Meow Wolf Denver
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@bluegrassreb1
3 years ago
and this wasnt designed?
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@mlauntube
2 years ago
God's design for life is so amazing. I just don't see how anyone could believe that life came from rocks; that is just so silly.
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@ughugh3556
2 years ago
How the hell does something like this "evolve"?
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@yns7430
2 years ago
When we able to make artificial mitochondria
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@ajb408
3 years ago
Meow Wolf took me here
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@megangeorge437
1 year ago
Meow Wolf Denver sent me here
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@benlee5039
3 years ago
So basically: its magic
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@EntityAiden
8 months ago
Got this video from meow wolf
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@gtbproductions1
3 years ago
How can anyone say we evolved from nothing that happened to appear in the ocean. We have a great creator, God. Do you really think this all happened by accident???
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@L4v4molly
2 years ago
Fussilat 41:53
سَنُرِيهِمْ ءَايَٰتِنَا فِى ٱلأفَاقِ وَفِىٓ أَنفُسِهِمْ حَتَّىٰ يَتَبَيَّنَ لَهُمْ أَنَّهُ ٱلْحَقُّۗ أَوَلَمْ يَكْفِ بِرَبِّكَ أَنَّهُۥ عَلَىٰ كُلِّ شَىْءٍ شَهِيدٌ
We will show them Our signs in the horizons and within themselves until it becomes clear to them that it is the truth. But is it not sufficient concerning your Lord that He is, over all things, a Witness.
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@markmanning2921
3 years ago
but you will never admit that this was CREATED by the creator but instead insist that all this was caused by a random event in some pre-historic puddle of mud where said puddle of mud jumped up and said "Im Alive!"
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@amira6405
1 year ago
I just clicked on this video. 10 seconds in and I am welcomed by a voice I recognize. The voice of a fellow Jamaican (RIP to Robert Lue). It's so surreal how just a voice can connect you to someone and now to a video I am wholly excited to watch and learn from.
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@VectorOfKnowledge
2 years ago
Given all the complexity of biology, I can see why some people would be too lazy to learn about it properly and would just be like, "Ah, fuck it. God made it."
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@aalokshah6207
1 year ago
why can't we take other gases of oxygen family to accept our proton ... for like if we did use sulphur we would be releasing H2S and that very good for anaerobic bacteria(specifiaclly sulphur bacteria) and..............if that was true on earth there would be a cycle between bacteria and us animals without having plants may be.... on the whole planet
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@8starsAND
3 years ago
I'm here at 4.51 am...
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@Starfire777
2 years ago
GOD our creator is AWESOME A powerful DESIGN!!!
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@espy0008
3 years ago
Wow, the fact so many people believe this complex system, only being an extremely small part of larger organisms, happened by chance and that all living organisms began as a single cell is proof of the smarter people get the dumber they are.
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@mudasirhussain3168
5 months ago
How the f people find this much information.... Maths student here 🖐
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@SmileyIsAlone
1 year ago
You know it’s Harvard, when you don’t know what’s going on!
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@NguyenNgocKhue-x8z
1 year ago
Không liên quan nhưng tôi muốn kể cho các bạn nghe một câu truyện: Tôi vô tình chụp ảnh đám cưới của người lạ. Bây giờ, họ gửi cho tôi một thư cảm ơn vì đã làm cho họ có một bức ảnh đám cưới tuyệt vời, mặc dù tôi không biết ai trong đám cưới đó.
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@spookyaction
1 year ago
this is a very high technology. Much higher than humans currently developed. We dont know the origin of this technology.
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@QbutNotTheQ
1 year ago
This is how you burn a muffin. 😊
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@gnomologist
4 years ago
Would have been better to talk of hydronium ions rather than protons...
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@Sweta_thakur711
4 years ago
Every molecule is an universe in itself......
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@JoshButterballs
2 years ago
FYI This and similar research is commissioned as a means to understand the many ways to destroy the human body en masse.
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@Vmartin70EZ
3 years ago
Electrons are used to power those microscopic pumps 😳just like electron flow is used in todays electric motor powered pumps!
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@HussainMushtaq0
10 months ago
(ربنا ما خلقتَ هذا باطلًا سبحانك)
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@anjanaybajaj3402
1 year ago
if anyone is feeling down, just remember we indians are being taught this at 16 years of age
have a nice day
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@Passco666
3 years ago
Now my body is smarter and will produce more Mitochondria :)
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@outrooutro8328
3 years ago
why did scientists decided to figure out how respiration works in the first place??
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@blainefiasco8225
3 years ago
Those membrane tails look like they tickle.
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@spacewater5866
4 years ago
How come they don't show ACTUAL mitochondria as it looks in real life. I dislike these computer graphics. Show us real stuff under microscope.
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@kafiamir7129
11 months ago
And to think Allah has created us with all this perfection that not even an electron jumps anywhere else other than its destined redox centers. That promotes proton pumping and that promotes synthase rotation which promotes ATP synthesis. SubhanAllah❤❤ how can we think that Allah doesn’t care about us?
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@hasim2818
2 years ago
Kacaeli tıp
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@jak8790
1 year ago
How did we achieve this level of accuracy, evolution, maybe God, or what? this is a great design, a micro level of everything working in harmony, to keep us alive. I can't find the words to describe my urge, to know. Yet nobody else knows what is going on to help me understand. We don't know, even a fraction of the hidden truth inside us.
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@rufus4779
1 month ago
Evidence of GOD. All of this could NEVER have been initiated by accident.
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@Derpy1969
1 year ago
I see Pinkie Pie, Twilight, Rainbow Dash, Applejack, and Granny Smith.
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@lynne1609
8 months ago
Phenomenal. No intelligent planning in the creation of this system, hm?
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@astralmaster1692
2 years ago
And some people believe life is "An Accident"
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@MarkHopewell
2 years ago
Unimaginable complexity marred only by one single fact: this complex and majestical process is still ongoing inside Donald Trump as we speak.
Thank you for this animation and all the work that went into it, let alone the discovery of it!
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@aesius1847
9 months ago
It's hilarious to me how someone can watch this and think these systems created themselves 😂
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@zynius
2 years ago
In 2030 we'll simulate this on an atomic level.
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@markmd9
4 years ago
It showed how oxygen is used to produce water but from what I know we breathe in oxygen and breathe out CO2. Where's the part that shows how CO2 is produced?
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@edelweisslandscape
4 years ago
we are trying modifying something that we didn't know, coz we are not the creator.
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@katherinelanoue8173
1 year ago
Reply if you found this video through MeowWolf Dever, CO
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@rokus100
3 years ago
If you are not amazed, humbled by this stuff you just didn't get it
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@neuroboy2914
1 year ago
I'm making medicine videos with memes, so you won't get bored here bro :)
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@harishchad.
1 year ago
matrix
============8=9==6==3====
intermembrane space
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@allenharper2928
1 year ago
Aww, he didn't say the thing!😰
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@aveb1041
1 year ago
Did anybody else get sent here from Meow Wolf lmao?
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@boughrietmohamed9411
3 years ago (edited)
🎨🖌️☝️🧠💯 Allah Allah
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@User24427
5 months ago (edited)
Any NEET asperent? Here
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@meeraghodajkar3830
2 years ago (edited)
No need to memorize ETC afterwards watching these animation video
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@yolanda6392
2 years ago
bruh no one told me that enzymes were this BUTT ugly
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@JosiahFickinger
2 years ago
"The fool has said in his heart; There is no God"
Even though no matter the complexity, people will still yet say it evolved. It's foolish to say that complex systems of complex systems of complex systems all evolved blindly apart from the intelligence of God.
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@codyhaas1008
4 months ago
So.. solve the creation, edit into dna 🧬, and generate immortal children would be possible 🎉😮😮😮
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@kanayanfantv
3 years ago (edited)
Saying that this came from evolution in an INSULT to intelligence.
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@shefochi5566
2 years ago
There is no way this is made by evolution.
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@Dr.AhmadAlsyouri
2 years ago
then a blind man says where is the creator I can not see !!
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@averycarman5645
4 years ago
My 7 year old son just watched this for the first time and he loved it!!! He wants to know what other videos you have to explain how cells work?
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@valerierascon8528
2 years ago
Meow wolf did this 😢
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@UmarFarooq-ss7os
6 months ago
All this is clearly evident on the existence of One God who is magnificent and merciful
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@mnyhomie
2 years ago
Denver meow Wolf
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@maxjurish2589
1 year ago
If scientists can't see a creative God in this magnificent structure and function then God help them!
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@hz6612
2 years ago
Sobhana allah , allahou akbar
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@kokochanukrit9989
2 years ago
This reminds me of a turbine
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@abirhasan8731
2 years ago
My God! isn't it beautiful...
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@cctransfer17283
1 year ago (edited)
This is a joke. Felt like I was in the Mcdonald's ball pit/ car wash the entire video. Back in my days at Harvard, this poor level of editing would never fly. Action will be taken. Happy Halloween.
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@funny3511
4 years ago
My body is a huge power plant... ME: Dota and Pornhub
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@miketrissel5494
1 year ago
... and yet there are still some watching these amazing and miraculous little engines, thinking that all of these micro processes evolved separately, yet at the same time, to become the building blocks of life...... Romans 1:21 "...they became empty-headed in their reasoning and their senseless hearts became darkened. Although claiming they were wise, they became foolish and turned the glory of the incorruptible God into"......
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@ausumncf9754
3 years ago
Complex 2 looks like a fried chicken leg 🍗
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@marchelandersen6839
5 months ago
electric universe electric beings
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@koryschroeder2924
2 years ago
Did meow wolf bring anyone else here?
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@imagination3815
2 years ago
Ah yes 5Head
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@shadymcnasty5920
2 years ago
The fact this occurred naturally without design is absolutely mind boggling
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@mobiustrip1400
1 year ago
Reality is just a show. It's a matrix. It's a video 🤣
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@Firstfruits288
2 years ago
Peace I leave with you; my peace I give you. I do not give to you as the world gives. Do not let your hearts be troubled and do not be afraid. - John 14:27
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@shadow_-.-
1 year ago
Who got this from meow wolf
👇
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@ОльгаГейнц-м6к
1 year ago
Nur Gott konnte diese wunderbare Welt in uns erschaffen!🙏🙏🙏
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@boughrietmohamed9411
3 years ago
Allah Allah tout puissant
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@yogastakurukarmani
4 years ago
We r so complex n sophisticated... Bow down 🙇🏻♂️ to nature's intelligence
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@JosiahFickinger
2 years ago
It takes blind faith to believe these complex systems of complex systems of complex systems evolved with a blind purpose and without the intelligence of a creator God. Thanks for this fascinating and informational video!
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@EMMANUELKOLAWOLE-p2s
1 year ago
Thank a lot Dr pius oziegbe I will keep letting the world know about your good work and about YouTube channel ☘️ your herbal medication cured my HIV HSD AIDS completely am grateful doctor❤❤❤
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@jec1987youtube
2 years ago
Clearly this was not intelligently designed and happened by chance coupled with random mutation.
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@adairjanney7109
1 year ago
I can believe in God forming by accident as an energy being before believing all of this happened by cosmic accident
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@girlandchocolate2012
2 months ago
Meow wolf brought me here
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@raylol460
10 months ago
ap bio students wya
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@satendralodhi5552
4 years ago
Please Hindi Mai samghaiye
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@DuumaZ
4 years ago
"Just as man made powerplants" yep just wait a couple of billion yrs and this kind of machine will just pop out on it's own. Not to mention the whole cell itself... there must be a creator.
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@philipb2134
4 months ago
This is a high-grade explanation. Lower margins of comprehension might better fulfill the didactic purpose.bleh
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@dabidmydarling5398
2 years ago
Who is here from ap bio?
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@damaster7276
4 years ago
Now reverse the process and we can drink water and produce Oxygen
Biokemist
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@fadlulaiabdu-raheem4612
1 year ago
And they said there is no God.
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@holdensilvey
1 year ago
Who's here because of Meow Wolf?
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@TylerSmith-is8im
2 months ago
Like if Meow Wolf brought you here
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@ehhhe
2 years ago
Meow wolf sent me here
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@colelarson1201
2 years ago
Meow wolf sent me here
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@pavelshalnwv8494
1 month ago
How great is the Lord!
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@hello-fw1pd
1 year ago
Do atheists really think that all of this happened by accident?
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@corbalord
1 year ago
Complex 3 looks like fried chicken lol
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@bryanagarcia4973
1 year ago
How many got here because of meow wolf?
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@eddienekitiah
1 year ago
The biggest proof of God's existence
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@333Paradigm333
2 years ago
I find it revealing that the narrator @ 1:28 compares the ATP complex to an man made power plant, and whereby he unwittingly invokes the principal of intelligent design. The impossible complexity of a "simple cell" cannot come to being by "chance & time". There is the appearance of design because it has been designed by God himself. Jesus is God incarnate in the flesh, he died on the cross as a substitute for the sins of the world (yours & mine).
"For God so loved the world, that he gave his only begotten Son, that whosoever believeth in him should not perish, but have everlasting life. For God sent not his Son into the world to condemn the world; but that the world through him might be saved. He that believeth on him is not condemned: but he that believeth not is condemned already, because he hath not believed in the name of the only begotten Son of God. And this is the condemnation, that light is come into the world, and men loved darkness rather than light, because their deeds were evil." John 3:16-18
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@marshalljordan2416
1 year ago
The electron transport process could not evolve by random mutations and natural selection. Therefore God must exist. “For the wrath of God is revealed from heaven against all ungodliness and unrighteousness of men who suppress the truth in unrighteousness, because that which is known about God is evident within them; for God made it evident to them. For since the creation of the world His invisible attributes, His eternal power and divine nature, have been clearly seen, being understood through what has been made, so that they are without excuse.” Romans 1:18-20.
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@abbigailhoffman1748
1 year ago
anyone else here from meow wolf?
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@mhdrn4484
2 years ago
this is plan of God , we are the stream of electrons . a dance of energy
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@IbrahimJawabreh-gk5dr
1 year ago
سبحان الله
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@수하긴
4 years ago
More oxygen please
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@davidrobinson6861
1 year ago
Meow wolf brought me here
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@dunk_the_munk2174
7 months ago
Who here from meow wolf ?
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1 reply
@sayedelghairb8640
3 years ago
Glory be to Allah 🙏🤲🏻❤️❤️❤️❤️❤️❤️❤️ Creator of everything
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@samirsha6762
2 years ago
God is the greatest 🙌...wonderful creation
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@salmonkill7
1 year ago
I can really see the ATHEISTIC ARGUMENT for how life just began by blind accidental chance! The simplicity of this process is really what sold me on ATHEISTIC ABIOGENENESIS....
NOT!!
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@thoughtthinker9300
1 year ago
All of this, no matter how complex, comes down to the very same BEGINNING QUESTION.
If in deed we are too complex to be created by random chance happenings, and we were purposely created by design.
HOW was the first being or whatever in this chain of life and creators created? BUT BY THE SAME CHANCE OF RANDOM HAPPENINGS, THAT ARE SAID IT'S IMPOSSIBLE TO DO.
Or in short.
Who and How was the first "????" that was created, CREATED?
Or is that us?
Or where and who or what "was it" ?
This is and may always be the ultimate "BEGINNING QUESTION".
ENJOY
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@imovertheocean
3 years ago
but are the complexes republican or democrat? That's the burning question, surely
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@xwsftassell
3 years ago
Why you should smoke cigarettes.
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@MaskedMarble
2 years ago
Truly God’s design of life is amazing. If one of these pieces were functionally missing, life wouldn’t be alive. Thanks to God that he had the foresight to put this all in place from the inception of life’s creation.
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@akbarshoed
1 year ago
No God. Stop thinking about God, please.
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@evanrutherfordlazyahole9079
1 year ago
Im not an android leave me alone.
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@jele38
4 years ago
What I learned from this is that our way of making atoms into others is a waste of energy and atoms are simply Legos looking for the right pice to snap to and we simply need to put them near eachother for it to happen and the energy given off by this reaction can be harnessed in cold fusion the same way our cells use it to praduce it into potential usable energy.
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@3zan6bel9
3 years ago
Racist Mitochondria, making a difference between protons and electrons.
Not very inclusive
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@ajmalabidin1307
1 year ago
SubhanAllahil Azizul Hakeem
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@amszulu
9 months ago
lol Meow Wolf Denver brought me here
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@Daubix
1 year ago
Meowwolf gang
👇
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@practicalengineering6965
1 year ago
God is awesome
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@ErikS-
4 years ago
And Darwin thinks this is something that randomly evolves in nature...
I dont believe it. This complex of proteins looks very engineered.
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@Amrelmasrii
1 year ago (edited)
wow ! Look how great the creation of Allah is, I really pity the disbelievers and atheists, use your mind and open your heart bro!
Allah Subhanahu Wa Ta'ala said:
"Do they not contemplate within themselves? Allah has not created the heavens and the earth and what is between them except in truth and for a specified term. And indeed, many of the people, in [the matter of] the meeting with their Lord, are disbelievers."
(QS. Ar-Room 30: Verse 8)
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@geocacheguy6736
1 year ago
This video proves there is no God lol
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@ayushtanwar6074
5 months ago
Neet aspirants
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@chynnadoll3277
4 years ago (edited)
And all this happened by chance, over billions of years, from a single organism accidentally formed.........YEAH, RIGHT😏....I DON’T THINK SO... How great Thou art, Heavenly Father❤️❤️🙏! John 1:3 (KJV): “All things were made by him; and without him was not any thing made that was made.”
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@ketssa
4 years ago
God is great
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@saysHotdogs
1 year ago
biology is just fat chemistry change my mind
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@paracletus3166
3 years ago
Glorified be God
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@kxmode
2 years ago
"O Jehovah, . . . I praise you because in an awe-inspiring way I am wonderfully made." (Psalms 139:1, 14) 🙂
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@bryangoldfield3861
3 years ago
The melted lettuce preliminarily number because ray cytopathologically advise until a thundering ptarmigan. meek, young design
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@ivin6415
2 years ago
Repent and believe the gospel of Jesus Christ
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@snapper1627
2 years ago
funny how this all came about without intelligent design...
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@vickiecastro433
2 years ago
Please do not add your convoluted personal comparison. Facts only
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@82ndAirbornesoldierofchrist
1 year ago
And just think, this was all because of chance with enough time, with no intelligent design.
Not a chance.
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@madrugade8242
1 year ago
Ok, so who can tell me with a straight face that all this just evolved by itself, through a purely random, undirected, creator-less process?
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@samphel4478
1 year ago
0/10 not recommend
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@Firstfruits288
2 years ago
Lord Jesus Christ peace is an inner treasure, growing within you as you trust in me. Therefore, circumstances cannot touch it. Be still, enjoying peace in my presence. - Alyssa Bomber
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@lukehelpmetakethisdangmaskoff
2 years ago
Chance mutations eh? The crap we believe...
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@iloveSUVs
7 months ago
Do you really believe this happened by chance?
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@barnarus
2 years ago
And who designed this????????????????????????? You know the answer........
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@grantfryer407
3 years ago
and you still think all this came about by chance (THEORY) of evolution 🤣
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@oleoelamparina53
1 year ago
That's why I beleave in Jesus. His wisdon created this and much more we yet don't know.
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@jacobogutierrezsanchez
1 year ago
For me, this is support for the existence of an Intelligent Designer.
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@Gerdaldfighterkid
4 years ago
that cant just be a naturally occurring accident, how could evolution had given it the direction to accomplish these goals
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@theHentySkeptic
2 years ago
Everything you see here is the accidental accumulation of tiny bits of it over time... hmm?
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@Firstfruits288
2 years ago
Be still and know that I am God; I will be exalted among the nations, I will be exalted in the earth. - Psalm 46:10
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@nickkrug8157
3 years ago
God is great !!!!! Do you truly and really think that this belligerent amount of complication evolved in some "POND" somewhere a million years ago...!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
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@sumhump1075
2 years ago
wack
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@Vmartin70EZ
1 year ago
These Microbiological Machines and their complex working System cannot be other than the result of Intelligent Design.
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@kaiseraugustus1393
3 years ago (edited)
And btw, of course, all this happened by chance... for sure... :D Darwin was dead wrong....
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@Firstfruits288
2 years ago
The Lord make his face shine upon you and be gracious to you; the Lord turn his face toward you and give you peace. - Numbers 6:25-26
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@Firstfruits288
2 years ago
Take time to be still in Lord Jesus Christ's presence. - Hannah Bomber
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@ryanramkalawan8441
8 months ago
Im here from meow wolf
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@munzak27
3 years ago
OMG, why do I just see it now and understand now :(
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@oluwanifemikim1996
1 year ago
Now tell me God isn't wonderful 😌❤️
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@user-um3yp7dl1n
11 months ago
thats the creation of god
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@Kazmir
3 years ago
This is a joke, right?
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@marinator4988
1 year ago
inaccurate
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@gavincurtis
1 year ago
iT's a MiRaCLe oF eVOluTIOn.
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@jiangxu3895
4 years ago
This is fuel cell made by God.
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@ardeleanion4435
3 years ago
BS
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@skyward7699
3 years ago
GLORY TO THE LORD
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@Rob8729
4 years ago
Random evolution....yeah sure.
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@kendod1637
2 years ago
God made.
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2 replies
@dwaynerobinson6494
1 year ago
Thank you Yahweh
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