Saturday, August 20, 2022

Origin of Mitochondria

"Origin of Mitochondria, The Little Engine That Climbed the Mountain of Evolution" 38,958 viewsJul 20, 2016 687 DISLIKE SHARE DOWNLOAD CLIP SAVE Case Western Reserve University 24.4K subscribers Title: "Origin of Mitochondria, The Little Engine That Climbed the Mountain of Evolution" Speaker: Joe C. LaManna, PhD Date: 4/19/16 Chapters 151 Comments rongmaw lin Add a comment... joe schmo joe schmo 5 years ago That was an excellent talk. Congratulations Joe LaManna. 13 Luke Schneider Luke Schneider 1 year ago Great video ! Thanks for posting ! Question.....how does ATP leave the mitochondria ? What transports it out so it can be used in the cytoplasm , for example ? 2
Nick Lane: Origin of the eukaryotic cell 38,564 viewsJun 27, 2017 652 DISLIKE SHARE DOWNLOAD CLIP SAVE MoleCluesTV 8.2K subscribers Dr Nick Lane's lecture at the Molecular Frontiers Symposium at the Royal Swedish Academy of Sciences, Sweden, May 2017. The topic of the symposium was "Tailored Biology". Check our YouTube channel for more exciting science videos! For more information, visit www.molecularfrontiers.org 183 Comments rongmaw lin Add a comment... Alexander Kovaleski Alexander Kovaleski 3 years ago Nick Lane is pretty good speaker. This is a really well organised and informative lecture. But read his books. The books are absolutely stunning. 22 Marc-André Brunet Marc-André Brunet 3 years ago I really love this lecture because👉 Rocks and Chemistry Makes Good Biology !! 📊 Bravo Nick your lecture is the Best, that's my fourth time viewing in 4 different place, Bravo again👍 3 Rob Inson Rob Inson 4 years ago Very good. Thanks for sharing. 3 Last Chance Last Chance 1 year ago Nick Lane is brilliant, articulate and an interesting speaker. He, like all other OOL scientists is doing his best to explain the unexplainable. Nobody was there, no fossils exist, and no similar process is happening now. But since mitochondria have the same size, shape and membrane construction as bacteria...It's as good a theory as any. Unless one invokes special creation at this point in evolution, there may be no other option. 1 Travelling on Uptozion Travelling on Uptozion 1 year ago Thanks for sharing the details 1 Max Doubt Max Doubt 4 years ago We're closing in on LUCA. Very exciting! 6 My OpenMind My OpenMind 3 years ago (edited) In the transition from low entropy universe to a high entropy universe, life is an efficient adventure probably inevitable #catalyst which accelerates that process. (Speaking metaphorically). 1 thomas hess thomas hess 1 year ago We all know things get more complex over time. David Wilkie David Wilkie 1 year ago The life of meaning, (might be Vogon Poetry), could start with bio-logical clocking recombinant Superposition-point Singularity Superspin re-evolution cause-effect of e-Pi-i omnidirectional-dimensional logarithmic interference positioning that is i-reflection containment time-timing. And under the circumstances, the Holographic Principle Modulation Mechanism Image condensation is self-defining in/of complete explanation.., here-now-forever. It has to be self-consistent with WYSIWYG QM-TIME resonance floating in flat-space ground-state No-thing-defined eternally, and so is just about the most "unsatisfying" answer intellectually, because it's constant condensation circulation sequences of divergence-convergence perspectives, Quantum-fields Chemistry and "dumd luck" of pseudo random cycles of Uncertainty. It's always NOW.., and that is that. Derrick Bonsell Derrick Bonsell 1 year ago At least British schools teach evolution... 4 Steve Deasy Steve Deasy 1 year ago Develop morality in preparation for the coming AI singularity. 1 Christoph Küstler Christoph Küstler 3 years ago I used to believe all this, until I watched a few lectures of James Tour. Then it became very clear to me, that we know absolutely nothing about the origin of life, or of the eukariotic cell for the matter. 7 Александр Петров Александр Петров 4 years ago Oxygen:the molecule that made the world ⭐️⭐️⭐️⭐️⭐️ 5 Saeed Zafar Saeed Zafar 1 year ago Alright, but why didn't photosynthesis evolve multiple times. All chloroplasts are descendants of ancient Cyanobacteria, why didn't Thylakoids evolve in Eukaryotes? A3Kr0n A3Kr0n 2 years ago "This isn't working". If I had a nickle for every time I heard that during a lecture... 2 Ard D.C. Ard D.C. 1 year ago on the question why bacteria only formed eukaryotes once is simple: competition. microbal eukaryotes exist and bacteria can't compete with them on a multicellar level in the ecosystem; the roles in microbal societies have become fixed. further more there's probably a high level of co-operations among them; symbiosis. When society works together they can conquer the world 2 pkr pdl pkr pdl 1 year ago (edited) Can please anyone answer me on 1 question? How did human as a mammal shift in diet preference? Are human really an omnivorous or is it just a societal construct in view of survival of fittest? How mammals had been differentiated into carnivores and also as herbivores in natural selection process? This doesn't make sense. Unlike today world where cows are fed with meats. Lets kill all vertebrates and invertebrates below us for survival. Dietary preferences for survival doesn't make any sense in evolution. Just a fossil and observational findings in eukaryotes doesn't confirm evolution. Evolution theory need modification phil smith phil smith 1 month ago Wait, has this guy got just the one talk?! Jess Lyn Jess Lyn 1 year ago #AwarenessConsciousness RonJohn63 RonJohn63 3 years ago 14:44 I don't know, therefore God. Or space aliens. 4 Hainet Korea Corporation Hainet Korea Corporation 11 months ago The Origin of Life is Chemical Synthesis.Marine algae(green seaweed):Cellulose is a cell Ansfrida Eyowulfsdottir Ansfrida Eyowulfsdottir 1 year ago I wanted science, not a stand up comedian. {;-;-;} 3 Peter Miesler Peter Miesler 3 years ago 28:00 1 Long Castle Long Castle 2 weeks ago So right off the bat, the very first scandal was sex. bob dobbs bob dobbs 3 months ago he thinks this is all some happy accident. Noel Cruz Noel Cruz 9 months ago And... After 44 min... We are still waiting for the explanation OF THE ORIGINS, not "adaptive" or "evolutionary must have" remarks and opinions, and other "not working" stufff... 2 John M. John M. 1 year ago Lmfao 1 Simple Jack Simple Jack 8 months ago Why is he allowing only the possibility of evolution? Why not intelligent design for example? 1 brian jackson brian jackson 1 year ago Where do they get these "Billions of years" from. Can they prove it ?? No, they can't !! 1 Clueless Clueless 2 years ago Sorry, evilution is dead. 2 R L R L 1 year ago What a load of bollocks and wishful thinking. And he still doesn't answer the origin of eukaryotic cells, he just muddies the water instead. 1 Rudolph Dandelion Rudolph Dandelion 3 years ago To sum it up, mitochondria is the powerhouse of the cell 27 joe schmo joe schmo 5 years ago (edited) Eukaryote = nucleus mitochondria converts ADP to ATP? Ah, it's all explained after 41 minutes, a hydrogen concentration gradient (between outer/inner membrane space and the matrix) creates the conversion. Amazing. 4 Patriot Joe Patriot Joe 11 months ago Great video! 1 joe schmo joe schmo 5 years ago Whoa, this is the best illustration and explanation of the electron transport chain...41:53...I've ever seen or heard. 3 Roger Scott Cathey Roger Scott Cathey 2 years ago Lehninger's Principles was one of my favorite texts. T.C.S. T.C.S. 1 year ago Thank you. Very interesting. Zangetsu Zangetsu 3 years ago there is often severe muscle wasting in people with cancer. one theory is called: Nuclear Meltdown, and it concerns mitochondria degradation. Michael Wiggs and his crew made a mouse model with implanted cancer cells and monitored the health of the mouse and many indications for four weeks, which is when the mice would be euthanized so they didn't die from the cancer. many of the indicators they monitored did NOT show a steady degradation, but instead would show minor degradation for the first three weeks, and then a LOT of degradation in the fourth week, and the mouse would be near death. But, when they monitored mitochondrial function, they noticed it degraded in a stepping stone fashion. this indicates that mitochondria show early changes we can investigate to see if we can intervene in the degradation process before severe muscle loss becomes deadly. 3 D1craigRob D1craigRob 7 months ago mitochondria evolves into midichlorians, sometimes mistaken for the x-gene, giving humans superhuman powers. Marty Lawrence Marty Lawrence 3 months ago There are FIVE information codes in every cell, aside from blood cells. The five are the DNA code, the mtDNA code, the epigenome code, the 'sugar' code that lines the surface of every cell, and the lipid code making up cell membranes. All these had to work in unison. The makeup of these for life are mathematical impossibilities-by-chance. To say the ribosome sums up evolution is ludicrous. That is defined as a 10^50 or more. It's far too complex without outside intelligence to make it happen. On top of this, the Intelligent Designer is a master chemist with 65 different hormones in the human body. We are a creation.. Not an evolution. Mis-expression of the genes or the sequence of the mtDNA causes diseases. In healthy people it is finely tuned. This fits the intelligent design paradigm. 3 Robert Lunn Robert Lunn 2 months ago Is it impossible to get these folks with this knowledge to get better at presenting? I’ve head nothing but pounding from his hand waving. Important stuff which one has to pay attention to understand and they’re throwing in distractions. I know , I know, it’s “ get off my lawn stuff but please A3Kr0n A3Kr0n 8 months ago I love these videos, but it bothers me that you zoom in on single people in the audience. 2 BL1 BL1 5 years ago (edited) I don't want to sound mean but this speaker would benefit from some public speaking training. He has a maddening speaking style that alternates between halting, half sentences filled with lots of ums and ahs, followed by bursts of technical jargon, followed by more half sentences. There's often just too much detail when a simpler explanation would suffice. It often felt like the proverbial guy explaining how a watch is constructed in response to the question "what time is it?". I was able to follow along only because I'm already familiar with most of the subjects discussed here. 3 a a a a 6 months ago Brilliant JOSE SALAZAR JOSE SALAZAR 1 year ago 36:00 We need a lot of "faith" to belive that this is really possible!! 4 JonFrumTheFirst JonFrumTheFirst 3 years ago The Greys inserted mitochondria into a cell to start the process. The process led to us. It's called seeding, and they've done it across the galaxy. Even the greys can't move among galaxies, but no doubt someone else is doing the same thind elsewhere. YakSak YakSak 5 months ago (edited) But what is the chemical reaction or process that produced FIRST lifeform, whatever that may be? How does something go from non-life to life? 2 Stephen King Stephen King 7 months ago this presentation shows various theories on the origin of life but ignores the most obvious one: God. Such presentations are often presented as being objective, but they fall squarely into a faith system that denies or ignores God as a valid hypothesis. 3 Mizuha Joto Mizuha Joto 5 years ago We need Terahertz wave. Icen Arsin Icen Arsin 1 year ago Please stop those unnecessary shots of the audience watching... Adds nothing to story and subtracts feom time we can see the presentation. 4 Daniel Fahrenheit Daniel Fahrenheit 2 years ago I don't know how I really got here either VIRAT Singh VIRAT Singh 5 years ago if mitochondria came from bacteria then why it is not infectious,what if it goes out of control and start replicating. 1 C James C James 4 years ago 42:27 It's a Trap 1 JOSE SALAZAR JOSE SALAZAR 1 year ago 3:27 What about INFORMATION? 1 TheDudeKicker TheDudeKicker 6 years ago Can someone talk to the bald guy with the blue shirt and tell him to listen to the lecture. His questions are distracting and non-relevant. And.... he keeps coming to all these lectures. 2 Jess Lyn Jess Lyn 1 year ago #AwarenessConsciousness Deborah Dean Deborah Dean 7 months ago All in all, this lecture doesnt say anything new. I learned all this 50 years ago. Its basic cell biology. Caroline Mulenga Caroline Mulenga 7 months ago I'm sorry....is this man not prepared and familiar with the subject of the lecture? I cannot listen to another err, ah, ah err peppered between every few words. If you cannot articulate, don't speak publicly! Platzhirsch Platzhirsch 1 year ago lets then take a more advanced look at photosynthesis so that we may understand weather life without design is likely: How many people realise today that we cant reproduce the process of photosynthesis today, despite all our computers and labouratories? We cant reproduce it, thats how complex the biochemistry is. Why and how would evolution go about trying to produce a protein for binding pigment molecules before pigment molecules existed? If chlorophyll evolved before the antenna proteins that bind it, it would in all likelihood destroy the cell, so the proteins had to evolve first. But natural selection could not favour a ‘newly evolved’ protein which could bind chlorophyll and other pigment molecules before those crucial pigments had themselves come into existence! Each binding site must be engineered to bind chlorophyll a or chlorophyll b only or carotene only. The carotene molecules must be present in just the right places for quenching triplet states in the chlorophylls. Even if the pigment molecules were already around, producing just the right protein would be an extremely difficult task. It would not only have to bind pigment molecules only, but it would need to bind just the right pigments in just the right places in just the right orientation so that energy could be transferred perfectly between them, with a little lower energy at each step. Anything else would do nothing, or would transfer energy at random, and the complex would accomplish nothing at best and burn up the cell at worst. And there is another problem for evolution. The insertion of the pigment molecules changes the conformation of the apoprotein from about 20% to about 60% α-helical content.45 So evolution would have to produce a protein with a wrong shape that would assume just the right shape by the insertion of pigment molecules in just the right positions and orientations when those pigment molecules had not yet evolved. The energy transfer timeframe between pigment molecules in the antenna complex is between 10-15 and 10-9 seconds. The system that God engineered captures 95–99% of the photon energy for photochemistry, even though there are four other ways the energy can be lost during the slightly less than a billionth of a second the system has for capturing it.46 Humans certainly cannot begin to design systems with such efficiency, but the evolutionists are determined that chance, what Cairns-Smith47 calls ‘old fumble fingers’, can. Our understanding of the assembly of apoproteins with their pigments is very poor, but we do know that the chloroplast encoded chlorophyll a binding proteins of PSI and PSII core complexes are inserted cotranslationally into the thylakoid. Protein intermediates of the D1 protein have been observed due to ribosome pausing. It may be that this ribosome pausing permits cotranslational binding of chlorophyll a to the protein. This kind of controlled insertion, with synthesis of otherwise phototoxic material, is precisely what we would expect from intelligent planning and forethought, but how might ‘old fumble fingers’47 hit on such a scheme? All of the parts must be shipped to the right location, and all must be the right size and shape, down to the very tiniest detail. ATP synthase is an irreducibly complex motor—a proton-driven motor divided into rotor and stator portions as described and illustrated earlier in this paper. Protons can flow freely through the CF0 complex without the CF1 complex, so that if it evolved first, a pH gradient could not have been established within the thylakoids. The δ and critical χ protein subunits of the CF1 complex are synthesized in the cytosol and imported into the chloroplast in everything from Chlorella to Eugenia in the plant kingdom. All of the parts must be shipped to the right location, and all must be the right size and shape, down to the very tiniest detail. Using a factory assembly line as an analogy, after all the otherwise useless and meaningless parts have been manufactured in different locations and shipped in to a central location, they are then assembled, and, if all goes as intended, they fit together perfectly to produce something useful. But the whole process has been carefully designed to function in that way. The whole complex must be manufactured and assembled in just one certain way, or nothing works at all. Since nothing works until everything works, there is no series of intermediates that natural selection could have followed gently up the back slope of mount impossible. The little proton-driven motor known as ATP synthase consists of eight different subunits, totalling more than 20 polypeptide* chains, and is an order of magnitude smaller than the bacterial flagellar motor, which is equally impossible for evolutionists to explain. Evolution cannot account for the assembly and activation of rubisco. All attempts to reconstitute a 16-unit rubisco from any source have failed, so the assembly of rubisco must be studied in the chloroplast extracts. The eight large (L) subunits of rubisco are coded by the chloroplast DNA, and the eight small (S) subunits by nuclear DNA. The S subunit of rubisco is synthesized on free cytosolic polyribosomes* and maintained even during synthesis in an unfolded state by chaperones* of the Hsp70 class and their protein partners. When the small unit is brought to the import complex of the chloroplast, the fourteen-polypeptide chloroplast Cpn60 chaperonin protein associates with IAP100 (protein) of the import complex and can also associate with mature imported small subunits. The chloroplast Cpn60 chaperone is similar to the E. coli GroEl protein. After the unfolded precursor protein enters the stromal space, it binds briefly to a stromal Hsp70 chaperone protein and the N terminal targeting sequence is cleaved. The large subunits of the rubisco enzyme are produced by the DNA and machinery of the chloroplast itself and stored complexed to a Cpn60 chaperonin.This chaperone protein keeps the large subunit protein from folding incorrectly, and therefore becoming useless, and is also necessary for the proper binding of the eight large subunits; without it they will form a useless clump. In many plants, the large subunits are chemically modified by specialized enzymes before they bind to the chaperonin protein. There is strong evidence that chloroplast Cpn60, Cpn21 and Hsp70 also participate in the assembly of the sixteen-unit rubisco complex. After a soluble L8 core is formed with the assistance of the chaperonin proteins, tetramers (four-part complexes) of small subunits bind to the top and bottom of the complex to form the complete enzyme. There are almost certainly other chaperones and chaperone-like polypeptides or lipo-proteins involved that are not yet characterized but i cant write a textbook here. How do evolutionists explain how natural selection would have favoured a protein complex the function of which was to prevent a still-useless rubisco small subunit from folding outside the chloroplast? Before it evolved a way to get the protein inside, there would be no benefit from keeping it unfolded outside. How could blind chance ‘know’ it needed to cause large subunit polypeptides to fold ‘correctly’ and to keep them from clumping? It could not ‘anticipate’ the ‘correct’ conformation before the protein became useful. And evolution would need to be clever indeed to chemically modify something not yet useful so that it could be folded ‘correctly’ when even the ‘correctly’ folded polypeptide would not yet become useful. 3 Astra Zenica Astra Zenica 1 year ago Why can't we recreate it in a test tube then, should be easy 1 JOSE SALAZAR JOSE SALAZAR 1 year ago 16:35 This claim IS not prove at all? T N T N 1 year ago (edited) Give me a break make rna in the lab and ill understand how mitrochondria was made 70 yrs after miller eury and nothing first stuff made first explain how rna is made or membrane not mitrochondria is the master piece of life its perfect in design how did lipids carbohydrates and nucleotides combine what is the mechanism we dont know good point on nitrogen combined effects combined effects 9 months ago The origin of life is the thumb in the face of lol these Darwinian fanatics - they can argue as much as they want that the two are not related - 1 Mohammed Al-Shahri Mohammed Al-Shahri 11 months ago I don’t believe the Evaluation theory 1 JOSE SALAZAR JOSE SALAZAR 1 year ago 8:49 How about Inteligent Design? ID is prety much what we see in the astonishing complexity of Mithocondria, Ribosoms, DNA, and Life in general...Most of the "leading" hypotesis are only Garbage, Lies, Errors, Why mention them as "leading" in the first place? Where Did Eukaryotic Cells Come From? - A Journey Into Endosymbiotic Theory 478,266 viewsJul 22, 2019 23K DISLIKE SHARE DOWNLOAD CLIP SAVE Journey to the Microcosmos 679K subscribers 1.8 billion years ago, a cell ate another cell, but it didn't digest it, and without that happening, we would not exist. This week we explore the origins of eukaryotic cells and ask the question, "Are our cells more than ourselves?" SciShow's "Was the Apollo Program a Bad Idea?" https://youtu.be/Oo3A5QQj5U0 Follow Journey to the Microcosmos: Twitter: https://twitter.com/journeytomicro Facebook: https://www.facebook.com/JourneyToMicro More from Jam’s Germs: Instagram: https://www.instagram.com/jam_and_germs YouTube: https://www.youtube.com/channel/UCn4U... Hosted by Hank Green: Twitter: https://twitter.com/hankgreen YouTube: https://www.youtube.com/vlogbrothers Music by Andrew Huang: https://www.youtube.com/andrewhuang Journey to the Microcosmos is a Complexly production. Find out more at https://www.complexly.com 1,341 Comments rongmaw lin Add a comment... Sarah Sarah 3 years ago Hank: softly explains existential question of endosymbiosis Also Hank: "69%. Nice" 2.8K Mark Firman Mark Firman 3 years ago (edited) "If you think hard enough, you might begin to feel like our cells are more than just... ourselves." This quote will stay with me forever, that's for sure. 323 Ignacio Gonzalez Ignacio Gonzalez 3 years ago Can you talk about bacteriophages or antibiotics? You could make a timelapse of their effects on a colony and how it becomes inmune to them. 494 HorstEwald HorstEwald 3 years ago We like this content. And with "we" I mean the 77kg of cells sitting in front of the computer. 1.9K Journey to the Microcosmos · Okuhle Minyi Okuhle Minyi 3 years ago 7:19 "Studies have shown that up to 69% of the caloric requirements of the hydra..." 7:28 "Nice." Okay Hank. 1.1K Mike Boyd Mike Boyd 3 years ago I always struggled with the principle of Eukaryotic cells through biology class at school. This is by far the best explanation I've come across. Kudos! 147 marcelwo4jedynki marcelwo4jedynki 3 years ago I love how suddenly a channels like this spawns and I start following the lives of little guys and feeling for them. 362 Katya White Katya White 3 years ago This series brings me so much joy. I appreciate that it is slow and relaxing, but interesting at the same time. Keep it up Hank & Complexly! 24 Vincent HeroInc Vincent HeroInc 3 years ago I love the change in his voice. On other channels Hank is energised, fast talking and enthousiastic. It fits the content of that material, but here his voice is almost therapeutic. And then there is the psycodelic music to it. Keep them videos coming guys! 31 Atypical Paul Atypical Paul 3 years ago Humans are like a planet with different ecosystems within and on it. So amazing. 37 The Warmedic The Warmedic 3 years ago Keep it up mate ;love your content. Can't wait for the next video! 61 123Dunebuggy 123Dunebuggy 3 years ago Prokaryotic turning Eukaryotic is likely not just a great leap for life on Earth, but a likely huge barrier for life on other worlds ( if it exists). A great filter for the Fermi paradox. 62 sanity's quota sanity's quota 3 years ago I'm gonna have to save up for a microscope. I know this series is gonna create an obsession. 78 CK Keith CK Keith 3 years ago Loving this channel so much! Thank you for the content. Appreciate the magnification info, but is there anyway to include a scale in microns or some other unit for us micro nerds out there? 4 Stinger1986 Stinger1986 2 years ago Love the show. Keep it coming! The scientific accuracy and ability to make myself question my own existentialism is simply brilliant! Well done indeed! 1 Nick Newman Nick Newman 3 years ago This channel is amazing. I finally have an easy way to get into microbiology. 15 Do It Wrong Do It Wrong 3 years ago (edited) Best show in youtube. Period. Also it's the only show in Youtube where Hank speaks in a chill mood(Actually every Hank's speaking mood it's perfect) 7 A A 3 years ago Absolutley wonderful, captivating, insightful and relaxing videos. Can't wait to watch more! Wonderful channel. 4 NoSkill NoSkill 3 years ago "69% of the caloric requirements of the hydra is satisfied by its algal symbionts....Nice" 😏 271 Planet coin Planet coin 3 years ago Thanks for the great content Hank, I wish more people turned into learning more about nature and science, this is an excellent way to do so, love your channel!! reggietheporpoise reggietheporpoise 3 years ago Man, I really love these videos. Thanks for taking the time to put them together. Any chance you guys might at some point do a video featuring Dictyostelium discoideum? I’d love to see some beautiful footage of them doing their weird dicty things. I’d love to hear what you guys have to say about their apparently altruistic sacrifice, and all the other weird things that make them fascinating. Rocco Rocco 3 years ago These are such great videos!!! I have just taken my first bio class and this was an excellent way to see what else is out there. Please tell us all about each of the microbes! Yuri Castaldo Yuri Castaldo 3 years ago I'm loving this channel so much!! I'm so happy I've found it! 🤩 Amazing idea. Exploring our invisible but closest world, is so fascinating! I think I'm gonna find a microscope as soon as possible! 😉💪 Thanks again for this work. 😘 John Vance John Vance 3 years ago Hank, this series is every bit as good as I’d hoped when you announced it, and then some. Thanks for being the change you want to see on the internet. Nabusco Nabusco 3 years ago We all know that the mitochondria is the powerhouse of the Eukaryota cells. 135 Random Mcranderson Random Mcranderson 3 years ago This is by far my favorite channel from your group. Great videos so far! ZAPtomic ZAPtomic 3 years ago Thanks for doing what you do! I'm so glad this channel got started. 2 chelsea plemons-jones chelsea plemons-jones 2 years ago Hank, I love this entire channel. I’m so happy I discovered this as my pandemic time, labless, zoom lecture microbiology summer semester just started last week (my last nursing school prerequisite, happy dance!). You’ve helped me through so much of my nursing sciences journey via crash course, thank you! My brain assimilates new info macro to micro so your Sean Shannon-esque “cliffs notes” presentations were super helpful to pair with lecture. I stumbled upon this channel by happenstance the other night, and I’m so glad I did. I have to say, your calm voice (in my humble opinion) is perfect, and the microcinematogrophy in these episodes is absolutely amazing, elegant, and mesmerizing. This channel is my new “It’s after midnight-my brain is fried from studying-I’m too tired to do real schoolwork-but I need to input all the things” bedtime story. Thank you so much for all you do 🙏🏼❤️ DrDogcat DrDogcat 3 years ago Love this YouTube channel, hope it continues to grow with each episode. Adawg 303 Adawg 303 2 months ago I have learned so much from this channel thank you for being such a great teacher. Seeing it for real instead of in a book makes it fun Zizumias Zizumias 3 years ago Hank: "up 69% of the..." Me: "nice" Hank: "nice" 407 Janet N. Janet N. 3 years ago This is my new favorite science channel. Seriously. The videos are stunning, and Hank's narration coupled with the music is just the calm we need in this crazy, messed up world! Also, really fascinating! Who knew so much went on in a water drop? Nathan Robertson Nathan Robertson 3 years ago I love this channel! I would like it if a micron bar were included in every scene and list the type of microscopy used to get the images, such as dark field, phase contrast etc. Daniel Mewes Daniel Mewes 3 years ago It blew my mind when I first learned that mitochondria had their own DNA a few years ago. So fascinating. PaladinSalt PaladinSalt 3 years ago I would love to see a video on your set up, how you store these microbes and what equipment you use. Great video! The_Heart_Chakra The_Heart_Chakra 1 year ago (edited) Thank you! I call into question the directionality of the initial Eukaryotic relationship in endosymbiotic theory. Instead of the theory that one cell ingested another but failed to digest, it could have been a situation where a cell was looking for a temporary or a permanent safe home and formulated a way to withstand digestion and utilize the larger host as a protective barrier against a presumably hostile environment? Jim V Jim V 3 years ago (edited) "I'm just gonna watch some Journey to the Microcosmos while I have a snack, should be a good mental break." 10 minutes later "Like wtf even am I?" 153 aga aga 3 years ago Beautiful microscopy ! Great videos - keep 'em coming ! Gamer3172 Gamer3172 3 years ago Please keep going! I love this videos. I am so into microbiology. It so awesome to see those incredible mikroscope catches you ve made! Maybe i m going to study it after my bachelor.. Microbiotic live always gets me excited. Anastasia PlantLegs Anastasia PlantLegs 3 years ago this is such an incredible channel, I’m unbelievably excited to see more from you aqueous solutions! Avery Young Avery Young 3 years ago Love this show! I have a suggestion: use a scale bar based on distance, not the magnification of the lens. As someone who plays with atoms and looks at small things everyday, using microns or millimeters would help people better perceive the size of these amazing creatures. 1 Lee Anne Johnson Lee Anne Johnson 3 years ago Absolutely amazing content. I can’t wait to use this in my classroom!!! A B Cars N’ Guitars A B Cars N’ Guitars 3 years ago Hope you guys are having a great week! Very much looking forward to this project :) 14 Reshi Reshi 3 years ago I really like these videos. I learned a lot of new things while also refreshing old knowledge. 1 Lia Jano Lia Jano 1 year ago Hi! I love the bits and pieces of humor added in! I usually struggle with understanding stuff like this, but you guys make it sound so easy! I'd really appreciate it, if you guys attach transcripts of your videos though. It would really help me out with reviewing the content. Thanks for existing! 1974woohooman 1974woohooman 4 months ago I love your channel so much. The music, the videos, the explanations, they're all very good. You deserve way more subscribers. Jolly Joy Jolly Joy 3 years ago Id love to see a series where in each episode you go in depth on a single organism, since videos like this one barely scratch the surface of a given topic. Motion in Mind Motion in Mind 3 years ago (edited) I'm really enjoying this series, thank you for producing it. I'm most interested in the seamless progression from the first single celled critters to "higher" organisms, like us. I hope you'll going through that timeline. What was the first Lifeform to survive on dry land, for example. Azzarinne Azzarinne 3 years ago I'm notified of very few channels' uploads, but I am SO glad this is one of them. 💖 39 Journey to the Microcosmos Cristian Garcia Cristian Garcia 3 years ago I love this channel! When are you going to have merch? I'd love to know how cells manage to move or take decisions? Its amazing! 1 seska1245 seska1245 3 years ago LOVE this new channel. I love seeing into the bacteria’s tiny little lives Jinx Dragon Jinx Dragon 3 years ago I have always wondered if one of the "great filters," from the Fermi Paradox, was overcome by one cell failing to digest another. It did lead to a whole bunch of more complicated life being possible on this world, so it clearly is a very important event. Yet it also seems to occur quite often though, but that is why we have a Paradox after all.... A Price A Price 3 years ago Brilliant videos - amazing visuals and I like the way Hank is voicing this a little more slowly and calmly. Isabelle Bergevin Isabelle Bergevin 3 years ago This was the best episode yet! The images, the narration, everything was perfect! I'm a college microbiology teacher and I would love to be able to share these with my students but unfortunately, I teach in French and a lot of my students aren't fluent enough in English to be able to appreciate this to its fullest. I was wondering if you series are translated in other languages or if they ever will be? Yuri Achnitz Yuri Achnitz 3 years ago I would easily watch an one hour long video of this channel 5 J Proffitt J Proffitt 3 years ago This is easily one of the best channels on here! I look forward to each new video Sarah Sarah 3 years ago I love this! It’s so calming and mind blowing at the same time 1 hermest99 hermest99 3 years ago I would love one on microbe movement and their movement patterns. It seems so controlled sometimes and so erratic at others. wizardofcroz wizardofcroz 3 years ago Always a good day when I get to watch a new video by you guys. You have sparked my interest in all things microscopic! Are there any other channels or resources you recommend to learn more about microscopic life? Gail Howes Gail Howes 2 years ago Thank you for making this video, I found it fascinating ! Some Toast Some Toast 3 years ago "and they became the same organism... Or did they?" Hey vsauce, Michael here 580 Julio Rojas Julio Rojas 3 years ago Absolutely love this channel already! Thank you for this Rogelinda Barraza Rogelinda Barraza 6 months ago Wonderful resource. Thank you for producing it! Denton Holmgren Denton Holmgren 3 years ago love this series! It needs to get more traction! Solomon Matthews Solomon Matthews 3 years ago Informative content, amazing visuals, no padding or hype. Wonderful! Tamar Ziri Tamar Ziri 3 years ago Thanks for this whole channel Hank! It's awesome! Adam Marciszewski Adam Marciszewski 3 years ago Hank Green, the ASMR teacher of the microcosmos!!! 3 Steve Shanafelt Steve Shanafelt 3 years ago This is rapidly becoming one of my favorite series on YouTube. Scatyricon Scatyricon 3 years ago these videos are informative, fascinating, and entertaining. im loving them! Lark Moerschell Lark Moerschell 3 years ago Adore the channel and I'm so excited to see more! Tom Talks Tom Talks 3 years ago You did a great job on this video! all the praise! good script and great information mixed with wonderful visuals and well-done narration. I really liked the pun at the end too :p Titans Tracks Titans Tracks 3 years ago Just what I needed today, I love how ambient and fitting the music is. These videos are always so chilling to watch! 💎 Zakareiya Abbassi Zakareiya Abbassi 3 years ago Thanks giving comes around "what are you grateful for?" Me-"when cells decided to eat other cells but not kill them" 17 Gail Howes Gail Howes 2 years ago What a wonderful subject with fantastic images, thank you so much! Skate Dad Skate Dad 3 years ago I'm so pleased with this new channel. Go guys! keep it up! It's so satisfying and peaceful L Crook L Crook 3 years ago This watches like an arthouse visual project, very impressive and well made. I never imagined such a channel needed to exist but now i wait impatiently for each video Alex Luck Alex Luck 3 years ago Fantastic video- really like your perspective. Thank you! 1 Marco Gardini Marco Gardini 3 years ago Thanks to the guys who run this channel, i love every single bit of every video. They’re just amazing. Rafaela Rafaela 3 years ago Yesss i can't wait for the Archaea episode!!! I remember learning about it in high school and they were sooo cool 6 MtnTow MtnTow 3 years ago LOVING these videos. Thank you so much! Bradley Tome Bradley Tome 3 years ago I am loving the mix of education and deeply relaxing ombiance that this channel's video's contain. Thanks Hank for bringing your audience from the VlogBrothers (where I came from) to this channel. GiggleBlizzard GiggleBlizzard 1 year ago (edited) Can I just say that you have the found the most absolute perfect music for these videos. It is just that, perfect. It fits the tone, the style, the subject matter and everything so incredibly well. God there's so much love in these videos I can feel it and they consume me. 1 Andrew Piltenko Andrew Piltenko 3 years ago The more i watch this channel the more i make sure it's the best one on YouTube. Thank you so much for what you're doing. a52Productions a52Productions 3 years ago I love this channel, but I find it hard to estimate the scale just using the magnification value alone. Any chance of including some other way of seeing the scale? Maybe like a little ruler that has a constant length of 0.1 mm (or whatever's convenient), but stretches and squishes with the magnification, appearing six times as large on-screen for 600% as it does for 100%. This would make it a lot easier to see the relative sizes of the different organisms. 1 Sami Hawasli Sami Hawasli 3 years ago Gotta find myself the elusive Nutella symbiant. Then my body will truly be complete 74 alfred beadman alfred beadman 3 years ago Love these videos, please make more!! Petros Schutz Schilling Petros Schutz Schilling 3 years ago I just wanted to say that your videos are completely related to an epiphany i had a couple of weeks ago. Im really glad i found your channel. 1 Alex Miller Alex Miller 2 months ago this video is beautifully made, and extremely descriptive of a very interesting topic. but out of the 471k views this currently has, i doubt most viewers could keep up with the frequent scientific jargon making it more difficult to digest. the viewers that could follow along likely already had sufficient background knowledge of micro-organisms. I'm still gonna save this to watch later cause it is such a cool video KingOfThePanduz KingOfThePanduz 3 years ago If possible I'd love to see a video on our gut microbiome! It's different in everyone, but I'm sure something interesting could come of it! Ramez Hachicho Ramez Hachicho 1 year ago (edited) You know what's kind of beautiful about this. Is that we've often attributed the origin of complex life to the evolution of predation. And no one can argue the role predation played in accelerating the process. But it sound here that what in fact really got the ball rolling when it comes to complex cells. Was an act of mercy. Perhaps the very first one. It was probably not selfless and certainly not emotional but still .. nice. 1 HohO HohO 3 years ago If only my lectures had this chill ass music playing, I’d be more entranced by all the amazing knowledge rather than buried and anxiety ridden lol 156 Samantha Lee Samantha Lee 3 years ago I love this channel so deeply and am amazed by every episode Get To Know Nature Get To Know Nature 3 years ago Wonderful as usual! I'm crossing my fingers for an episode on viruses soon. Theblacktiger Theblacktiger 3 years ago Would it be possible to see some of those tiny living thing from our own body ? So that we would see how we are walking organized puddle of life. :) Great show anyway, always amazed to think that life started at that scale and remained that way for so long. Æd Thompson Æd Thompson 3 years ago Really enjoying this series, and although I like SciShow etc, I’m really appreciating Hank’s softer delivery. 1 Ydoum Ydoum 3 years ago I'm having really hard time getting used to Hank not being all excited about some amazing scientific news and hearing his - what I would call now - his normal voice. Elhazar Elhazar 3 years ago This channel inspired me to get a better microscope. 5 Journey to the Microcosmos Simon W. Simon W. 3 years ago This is one of the highest quality channels on Youtube, by far! :) Life Happens Life Happens 2 years ago I love that you guys made this video! When people talk about endosymbiosis, they almost always talk about it as freak events happening in the distant past, which makes it seem sort of speculative. In actual fact, cells living symbiotically inside other cells is incredibly common. goosbums1 goosbums1 3 years ago I love this channel for many reasons with one being it’s actually really interesting and peaceful Mary Ann the Nytowl Mary Ann the Nytowl 7 months ago This, the way you described it, is really quite brilliant! I hadn't ever actually seen it described it like this, so - very good job, indeed! 👏👏👏👏 Avner Senderowicz Avner Senderowicz 3 years ago first time to the channel - what a excellent presentation. interesting, superbly narrated and visually stunning. subscribed. Cholula Hot Sauce Cholula Hot Sauce 3 years ago Making me worry my mitochondria are going to ditch their cells and strike out on their own. 27 jonathan verret jonathan verret 3 years ago Such an amazing step in the tree of life. It's not hard at all to see how a bunch of algae in an amoeba lead to the amoeba needing to eat less and less and eventually not at all. I'm looking forward to the episode on Archaea! Could you also please do an episode on the evolution of multi-cellular life? Ted S M R Ted S M R 3 years ago Amazing content! Thank you so much! Gamma Ray Gamma Ray 3 years ago Journey to the microcosmos is like a psychedelic trip, kudos to you and your team and keep doing your magic Brian Hutzell Brian Hutzell 2 years ago I remember having a microscope (an inexpensive one, to be sure), a chemistry set (back when they still contained all the dangerous chemicals you aren’t allowed to have now), a geology kit, and at least a dozen little Golden Guide science books. At some point, I foolishly decided I’d outgrown those “toys,” and got rid of them. Sometimes we make foolish mistakes while growing up! sigh Flora Azul Flora Azul 6 months ago Finally going to binge this channel. Absolutely lovely work here. TheCrippledHalfling TheCrippledHalfling 3 years ago "And blood-black nothingness began to spin. A system of cells interlinked within cells interlinked within cells interlinked within one stem. And dreadfully distinct against the dark, a tall white fountain played." 27 Capitus Capitus 3 years ago (edited) Rather than the magnification, or along with, could we have a scale bar (of 1um or so)? It would be way more telling to get an idea of the cells size. Great, great growing channel otherwise, looking forward to more :) Mateus Mateus 3 years ago I can't express enough gratitude to you guys responsible for making this channel! After learning about our bodies' mechanisms at the celular level in my university I became really interested in and amazed at these subjects, so to have all this beautiful imagery and information so easily accessible on youtube is a great pleasure to me. This channel has instantly become my favorite along with PBS Eons. Keep up the good work! Love from Brazil. Literally FF Literally FF 3 years ago So happy to see a new upload. This is so interesting and well made, the only negative thing i can say is that the channel is too new so there aren't more videos to binge. Menace (//P875) Menace (//P875) 1 year ago (edited) I love this channel.. I've always thought we are just macro scale bacteria, watching these makes me realise more than ever the fractal nature of the universe. If ever there was a "God" that created us, the microcosm would be the place to start looking. Not religious, but it's just how I see it. Sid Sid 3 years ago Thank you for talking slower on this channel. Absolutely fantastic content! Nick Sennett Nick Sennett 3 years ago The beginning of the video almost sounded like he was going to start narrating to the tune of the music 401 Lama Lama 3 years ago Ever since I entered computer science in university I really missed biology, which I really enjoyed but didn't feel was my field. These videos are amazing, makes me feel happy to continue learning more as a hobby! Ultimateo Ultimateo 3 years ago I can’t express how awesome this channel is 1 Vorname Nachname Vorname Nachname 1 year ago In evolutionary biology lectures my professor gave the argument of genetic transfer to the host's nucleus as a differentiation of a seperate endosymbiont and an organelle. Basically we have observed that mitochondrial and plastid genomes are far smaller than those of their free living ancestors since many of their genes have either become redundant and subsequently lost or transferred to the host genome. We can also observe this tenedency in the genus Paulinella who also aquired photosynthetic endosymbionts, and have undergone some, but not nearly as much genomic reduction as Mitochondria and Chloroplasts. 1 morningbear morningbear 2 years ago Thank you for making this sir i really appreciate the opportunity to your opinions Feynstein 100 Feynstein 100 3 years ago Hmm what if we could incorporate these algae into our skin cells? We could derive energy from sunlight and wouldn't need to eat as much. 🤔 5 Xavier Abhishek Rozario Xavier Abhishek Rozario 3 years ago awesome content as always ! 1 MisterTalkingMachine MisterTalkingMachine 3 years ago I remember when I learned about endosymbiotic theory in school, it blew my mind. Daniel Hernández Bañuelos Daniel Hernández Bañuelos 1 year ago This kind of interaction is really interesting, I resently got to see a study on Rhizopus microsporus and the holobiont Burkholderia. Really something. Bounce Back Coaching Bounce Back Coaching 1 year ago (edited) What happens when you open up an endosymbiosis and see if the green algae can live again outside of it's host. How it reacts when it is placed with other algae and when the endosymbiosis is placed in a stressful environment who is to die first? Also wonder if the endosymbiosis dies do the algae escape or do they go down with the ship? Thanks for the wonderful video! Iced coffee. Iced coffee. 7 months ago Stumbled upon this video, and upon watching, I noticed that the voice was familiar. I was very surprised when I found out that Hank Green was actually the person in this video. I grew up watching Hank Green on Crash Course and I absolutely loved his show. It's amusing how different he sounds between all his shows Bel Rick Bel Rick 3 years ago Eukaryotic cells are the equivalent of Object Orientated Programming 25 Max Deyes Max Deyes 3 years ago Award winning sounds and visuals. Really a wonderfully immersive show, 1 Sareseras Sareseras 3 years ago Being shown these visuals we'd see thanks to microscopes makes me hope to live long enough when we will have a 3D microscope, but the same goes for astrophysicians with their telescopes, hoping one day to view them in 3D like google street/earth view. Durjay Pramanik Durjay Pramanik 1 year ago Thank you for taking us on this journey. absolutely not crying cat absolutely not crying cat 2 years ago So nice. I already knew the most of information in that video, but visual part of the video, combined with voice and music, is wonderful enough to be watched. 1 Derek Webster Derek Webster 3 years ago I don’t learn a lot of big details through this content, but that’s fine; it’s so cool to get the interesting tidbits that are new to me, like the types of unicellular creatures that have endosymbiotic relationships. I learned about Hydras in my biology class a couple years ago, but never learned that some have mutualistic algae. R.O.T. Studios R.O.T. Studios 3 years ago Yeeesss, another great video to sate my obsessive lust for knowledge <3 20 Lukub Lukub 3 years ago This channel has exactly the level of energy i need right now. Gwendolyn Farms Gwendolyn Farms 3 years ago I developed a love of biology in year ten when my biology teacher took us to the local creek which was all but dried up and had developed an algal bloom. We collected our samples and saw cilliates and flagelates under our microscopes until the heat from the lamp cooked them. We then grew our creek water in petrie dishes with a loving blanket of agar. We went on an excursion to see the electron microscope in the research building of the local university.... That's right just to look at it. To be able to see moving cilliates and flagelates and amoeba and to see internal structures and cell walls is mind blowing. Thanks Hank... From the depths of my symbiotic flora (we call it flora but I think it is more correctly - fauna) Dave B Dave B 3 years ago I always wondered if there were cells living in cells like how we have trillions of cells does each cell have trillions of cells and so on Scott Wallace Scott Wallace 3 years ago How can I have never heard of testate amoebae before? Mindblowing. It seems obvious that the line between organisms is harder and harder to find because it doesn't exist. We need lines to pigeonhole things; that doesn't mean they obtain in the real world. Another great video, thanks. Cheers from sunny Vienna, Scott Loren Z Loren Z 3 years ago Any chance of getting a video that's just an hour of watching a single drop of pond water? I'd love to use it as a background while studying. 1 Average Person Average Person 3 years ago My mitochondria told me to watch this... They never make me disappointed... 11 Bose-Einstein Bose-Einstein 3 years ago I really like this timbre to Hank's voice. It's very different to his usually jovial and bombastic tone, but a welcome contrast that I can't help but adore. sukki110 sukki110 3 years ago it was always one of my insomnia questions, if my own cells feel as a part of something or if they are just making their own life… now the same is going on inside themselves! its CELLCEPTION!! Paul Barnhouse Paul Barnhouse 3 years ago I absolutely adore this channel!!! 1 Whedabra Kyovaer Whedabra Kyovaer 3 years ago Before this channel, I had no idea Hank had such a soothing voice. I could listen to this for hours. Omar Sharief Omar Sharief 3 years ago There’s a great book that covers this topic in great detail for those interested. It’s called the Vital Question by Nick Lane for anyone interested. Leo DeChant Leo DeChant 3 years ago Thanks for taking us on this journey, I've got my lunchbox packed 4 Paul Grijalva Paul Grijalva 1 year ago Thank you for all of your content! Eric Hewes Eric Hewes 3 years ago so now there's asmr style, hank narrated, andrew huang scored (on modular synth), philosophically oriented science content. this is the best channel. Mark Chapman Mark Chapman 2 years ago I read a hypothesis that, even if life has developed on many other planets throughout the galaxy, complex life like us might still be rare because our complexity is dependent on the energy that we get from our mitochondria, but given that one cell absorbing another and making use of it seems to have happened independently hundreds of times on Earth, maybe that isn't such a big deal. BJ Vynz BJ Vynz 3 years ago Well, I sure am glad that our brain puts together a single mind, or what feels like a single mind, despite every human actually being an enormous colony. Scrumptious Red Beans Scrumptious Red Beans 3 years ago In the future can you explore the similarity of our immune system to free living eukaryotes Sam Aronow Sam Aronow 3 years ago Hank Green whispers in your ear: ... ... ... ... "Hail Hydra." 117 I like turtles I like turtles 3 years ago Thank you for this beautiful and informative video. soip soip 3 years ago It would be very helpful if there was a scale bar, or at least show a 1x magnification for reference so we can imagine how small these things are FollowTheLaw Damit FollowTheLaw Damit 2 years ago This channel is awesome! However I would like less sophisticated information throughout the whole video or put another way maybe add some more information as it relates to us in our daily lives. Such as where would we see these organisms around us. Are they in our backyard, our food, the water we drink, in our cars, inside of us??? Furthermore how did it get there and how do they keep surviving if we keep cleaning or destroying them in our living areas. 1 Shy Dino Shy Dino 3 years ago I hope this is shown in classrooms. A big problem I had in highschool was that the people/videos narrating in a very boring manner. They already knew and were required to inform us. Hank sounds so excited about what he is sharing that it makes me so excited to listen to these. Joan Whack Joan Whack 3 years ago I love this channel more than words can describe Journey to the Microcosmos Demeter Ákos Demeter Ákos 3 years ago "Our cells are more than just ourselves" :) 7 James Russell James Russell 3 years ago So thankful for this channel. It goes well with my... extra-curricular activities. Semih Çorbacı Semih Çorbacı 2 years ago Thanks for the microscope images :) I pretty love it, awesome video with remarkable images. ❤😍 Daniel Torres Daniel Torres 3 years ago This needs to go on national Television all over the world. Such quality! Luis Aldamiz Luis Aldamiz 3 years ago I gained much respect for Hank since he speaks slowly and voices this channel, which is awesome! Denis mckenzie Denis mckenzie 3 years ago Friggin awesome, thank you so much for putting this together yevheniia yevheniia 3 years ago Oh, that last sentence is just in the best traditions of popular science shows! T-Shirt worthy, haha 3 Blitzmulthe 🏳️‍🌈 Blitzmulthe 🏳️‍🌈 3 years ago Honestly, Hank’s voice is so calm here compared to his usual voice that it took me until this episode to realize why the narrator sounds so familiar Drew Tramp Drew Tramp 3 years ago Cool. I wish we would of watched that during Biology class in High school. I might of got more into it. I couldn't stand the pictures and theories. Great video. Hopefully schools use it to inspire people. Anshuman Anshuman 3 years ago 124 k subs without hardly being a month ! Love the videos and narration ! You are the best Hank 1 Antor Khan Antor Khan 3 years ago Even in single cell level there is "protection business", fascinating! KrazyKaiser KrazyKaiser 3 years ago I need one of these videos to last literally forever, my lord, this is so calming. 1 Ahmed El Badaoui Ahmed El Badaoui 3 years ago When i demand money for protection it's wrong, but when an amoeba does it it's ok. Double standards. 8 Jacob Shaw Jacob Shaw 3 years ago Thank you for another excellent video. Maxwell Miles Maxwell Miles 3 years ago A request - can you guys put out a hour long video tracking only a single cell Seaslugsensation Seaslugsensation 3 years ago Finally, I've been waiting for this episode since they started this show! MegaRudeBoy69 MegaRudeBoy69 3 years ago Thanks for using the internet in this way, the way the creators intended. herobrineharry herobrineharry 3 years ago Here’s a question: how tall are microscopic organisms? From what I see on the screen, most seem very flat., with some exceptions, like tardigrades. 1 Left Light Left Light 3 years ago "Up to 69% of the caloric requirements of the hydra is satisfied by its algal symbiance... nice!" 6 ___. ___. 3 years ago Video upload time is 1/2 hour before my microbiology class... I love getting into the right headspace with these! Tan Christhoper Tan Christhoper 3 years ago Having asmr while learning new knowledge, surely my new best asmr channel! Gud job hank! You succesfully created a new asmr channel! Mary Rose Mabini Briones Mary Rose Mabini Briones 1 year ago Hi! I am a university instructor at the same time a probationary PhD student. I am interested of using this video in my research instrument. May I request for your email so I can formally ask you permission regarding this? Thank you! Stian Josok Stian Josok 3 years ago (edited) I'm enjoying the series so far. The imagery is amazing! The narration is on point! That said, the soundtrack was a bit distracting and tense for the content (especially towards the end). 2 Adeel Khan Adeel Khan 1 year ago May I know the kind/type of microscope put to use here? Also, these are from the local pond? I've always wondered what are the kind of lifeforms in the pond, that I am not able to see with my eyes. What I drew This Week What I drew This Week 3 years ago Why dont you say that three times? Within cells interlinked 38 TechCaboose TechCaboose 3 years ago Love it! Keep em coming Alex CA Alex CA 3 years ago This series is fantastic! MortalMercury MortalMercury 2 years ago How do the inside cells start replication at the same time with the outer cell? Alyssa Wyant Alyssa Wyant 3 years ago His voice is so relaxing. I love learning from Hank 1 L Dewey MD L Dewey MD 3 years ago What a well done video about endosymbionts! Narration and cinematography are great...AND... the music soundtrack is absolutely amazing! What a creative choice! What an artistic compilation for a science topic! Just in case anyone is interested, (either viewers or the creators of these videos), a marvelous book that explains the evolution of eukaryotes, AND a possible mechanism for how life evolved in the first place, is "The Vital Question", by Nick Lane, (biochemist, who leads the University College London "Origins of Life" Program, and has authored many other books). Biochemists are closing in on abiogenesis just as we're on the verge of detecting life on other worlds. A very exciting time to be alive and sentient!! Cinfoni Cinfoni 3 years ago I wasn't expecting a "69 nice" joke and that made it x1000 funnier 😂😂😂😂 7 Flavvs Da Silver Flavvs Da Silver 3 years ago This video takes me back to my university days... It feels like a good microbiology lecture, but gives me uncomfortable notes of population genetics lectures haha... I had such cognitive dissonance when I was introduced to the concept Dawkins' selfish gene theory... Ronald Morgan Ronald Morgan 6 months ago So, what keeps the algae taken in from the outside from reproducing? You'd think that if they had it good enough they'd take over the joint. Hi I'm APOP Hi I'm APOP 3 years ago One of the few channels where I don't mind it barely pass the 10-minute mark. If possible, please make longer ones! Bluecho4 Bluecho4 3 years ago I mean, we have a host of bacteria enslaved in our guts, that helps us digest food. Is the idea of organisms that use other organisms on a microscopic level really so strange? Lilith Eden Lilith Eden 3 years ago So small, so beautiful, so simple and yet so perfect . GuruOnNet GuruOnNet 3 years ago Gut bacteria in humans are another topic that would be very interesting. 4 fanjapanischermusik fanjapanischermusik 3 years ago this is a completel new perspective on live, never thought of it like this. Amazing, very cool, thank you! ŠP ŠP 3 years ago It's incredible to think about the fact that right now, trillions of cells in my (our our?) body are learning about themselves through a YT video. What a universe. mario vergara mario vergara 3 years ago A question. Those cells inside another cell have all the same dna or they have different dna from each other? Василий Мельник Василий Мельник 5 months ago I once watched a cool video of an alien (of course I know it wasn't real) who is said to be a human from the future. People asked them questions as if they were criminals and they answered. One thing I didn't quite understand back than and now like about it was that they said that we are all parts of the same life. There's no you and me, just life. And since we know all living organisms on Earth evolved from common ancestors, this starts to make sense. Especially considering how we all dependent on each other, almost like we all are just organels of one big planet-sized living thing William Frost William Frost 3 years ago I have to ask: what kind of screen is the displayed magnification designed for? Is it a 55 inch TV, a PC monitor, a tablet or just a phone? It’s just that whatever device the magnification correlates to could make a big difference 1 Duy Bear Duy Bear 3 years ago “Cells Interlinked Within Cells Interlinked” 6 Willian M. Willian M. 2 years ago why have I subscribed? because you not only show and explain about those interesting microorganisms, but your videos add up a lot of knowledge value such as when you said that chloroplasts have their own DNA which they use to create the proteins required for their function, thanks for the cool lessons. Johnny Woods Johnny Woods 3 years ago What about horizontal gene transfer, couldn't that have played a role in the origin of eukaryotes? Fayella Fayella 3 years ago This channel is underrated. The produciton quality is fantastic, the wideo quality is amazing. Watching these cells is mesmerizing. Riptide Monzarc Riptide Monzarc 3 years ago These videos are fascinating, but they reveal Hank has a soothing voice that would be perfect for meditation or bedtime stories. Also, we all know that life was created by Xzibit, and after 1.8 billion years he was like 'Yo dawg, heard you like cells, so we put some cells in your cells so you can phototroph while you heterotroph' GrapeNuts GrapeNuts 2 years ago Completely random question: would it be possible to keep a single hydra specimen and allow it to reproduce asexually then later sexually?, would this make the hydras produced sexually a clone in the same way that one's produced asexually are? And if so would it be possible to study the genetics after a few generations to see if any mutations have occurred compared to the original specimen and also compare the genetics to ones produced asexually? Cloude Cloude 3 years ago The first few words almost sounded like Hank was gonna bust out a rap to the beat. 5 Phillip Maciejewski Phillip Maciejewski 3 years ago Love this new style of narration! pixartist pixartist 3 years ago May I ask what microscope you are using and if similar quality images are achievable with relatively cheap microscopes in the 3 digit dollar range (excluding the camera)? Zenri 53 Zenri 53 5 months ago this answered a lot of questions i had thank you Dan Brees Dan Brees 3 years ago You have the best voice. You read incredibly complex and dry scientific research papers and I would have no idea what you are talking about but would remain 100% entranced. NewTypexvii NewTypexvii 3 years ago - Are our cells a part of ourselves? mind blown, thank you! Master Chief Master Chief 3 years ago 4:02 THAT MICROBE BE LIKE OH YAH! THAT'S THE CAMERA, LET'S DANCE EVERYONE! 21 Slysheen Slysheen 3 years ago I think Hank's soft narration voice is my new asmr. He's just so relaxing to listen to here. Celina K Celina K 3 years ago (edited) 4:53 couple of weeks of starvation 8:28 If you think hard enough you might begin to feel like our cells are more than just ourselves. - Hank 2019 Ihh Ihh 1 year ago Didn't ren realize this was Hank Green talking here, makes the channel many times better. Thanks Hank for your weird insight into the small life that builds the larger picture, "nice" sir Norton sir Norton 2 years ago These videos are more informative than entire highschool biology courses. P L P L 3 years ago With mitochondria I think it's more likely the Mitochondria ancestor was a parasite and was not eaten. Also given the 4 layer or double bilipid layer surrounding the nucleus, it's possible that the nucleus itself of a modern Eukaryote was it's own organism, meaning the modern Eukaryote is an amalgamation of at least 3 (4 for chloroplast containing cells) original organisms that have fused into one cell. Ryan Allen Ryan Allen 3 years ago Your voice is both soothing and ominous, idk how that works out... 3 sonorasgirl sonorasgirl 3 years ago This whole channel is lovely - I love to watch it before bed 😊. So soothing and beautiful steve p steve p 5 months ago i would love for you to explore each individual cell type inside our bodies. and dont stop there... i would love for you to to make oogle map of the human body in a microscope .... NO CGI ALLOWED PLEASE. im sure others feel the same way , and it might help you get more crowd funding cause u could potentially be on the frontier of exploring things in such a fasion. i would love to see a representation of a human dna under a microscope ria salvation ria salvation 3 years ago the best youtube channel of all times! thank you! Loni DeltaMuKappa Loni DeltaMuKappa 2 years ago Thanks for work ! It's fantastic ! Blaze O'Glory Blaze O'Glory 3 years ago I find it interesting that I can be so interested in content but still find it so easy to fall asleep to because of the mellow narration and calming music. BubblewrapHighway BubblewrapHighway 3 years ago JESUS CHRIST, HANK. Untangling identity is hard enough without having to wonder whether or not I'M ME. 4 z4zavala2 z4zavala2 3 years ago I would love to see a episode about Hydras. Jon Stevens Jon Stevens 3 years ago It would be helpful if definitions of terms were on screen when the term first appears in the video. Kind of like what you see in Cells at work. I don't remember everything from previous videos. rhiana smith rhiana smith 3 years ago Great job on this video! Jonathon Drogulus Růžička Jonathon Drogulus Růžička 3 years ago I'm so happy this channel exists! Nelturnax Nelturnax 3 years ago I hadn't noticed it was actually Hank hosting until he talked about the SciShow documentary. He's everywhere, what a madlad ! Sword of Tauberg Sword of Tauberg 3 years ago I picture photosynthetic algae holding up sign offering a 60% discount on nutrients in exchange for housing. 10 Χρήστος Χρήστος 3 years ago 6 years of biology in school and these vids are the first time that i learn voluntarily forkfour forkfour 8 months ago Just a little comment that idk if anyone else points out but the utter quality of these videos is so amazing and I want to thank you so much. Even something like the sound design is so thought out and detailed. It really adds to the experience Ghostrider guitars Ghostrider guitars 3 years ago (edited) Hi. I was just reading about massive depth of field technology Frazier’s lens has three revolutionary features: a “set and forget” focus which holds everything, from front of lens to infinity, in focus; a swivel tip so that, without moving the camera, you can swivel the lens in any direction, completing a sphere if need be and a built-in image rotator. This allows the image to be rotated inside the lens without spinning the camera. could this kind of lens or a microscope lens using this configuration be used for microscopic film? even the set and forget focus thing could change micro photography I thought? Ashish Singh Ashish Singh 1 year ago This channel has become my ASMR ❤️ I Can't sleep without this channel 😂 Toastwig Toastwig 3 years ago andrew huang is knocking it out of the park. Hopefully the music will become available somewhere at some point. Christopher Brüderle Christopher Brüderle 3 years ago WITHIN CELLS INTERLINKED. 4 John Coppola John Coppola 3 years ago (edited) am i going to have to wait a week for the next episode? this is fascinating. Thairin Khudr Thairin Khudr 1 year ago (edited) This exact thought came to me when thinking about how people grow organs for people who need organ transplants. Like, the cells are multiplying and growing by themselves, they're alive and thriving in a conducive environment, and then they're put into a person? They probably did come from a living person's cells, but they don't necessarily need to BE in the person to live and grow, they just need a nutrient-rich, moist, warm, pH-balanced environment. Like, damn, if that ain't another organism by itself? Glad to have similar a thought, albeit coming from different inspirations. 😊 Jonas Manuel Jonas Manuel 3 years ago Can you do a video about the sex pilus? I saw the video from Steve mould and I thought it was fascinating and I had never heard of it. Salsa d'Arte Salsa d'Arte 3 years ago So I'm wondering, what is a single organism? From the very small to the very big, like the impressive fungi in Oregon, identity in the sense we usually mean it, is to be put into question. Kabuki Syneri Kabuki Syneri 3 years ago "How did this happen? It took decades to come up with an explanation for how this billion year fairy tale came about" 2 газировка Obscured газировка Obscured 3 years ago Micro dude: the hydra blasm gasm bla bla... Me: dont even know how to connect points in his explanations anymore. But still me: 👁️👄👁️🍿 3 John H John H 3 years ago Do you think the perception of time dilates at this level? like all this inside of a raindrop, what happens then when that raindrop rolls off the leaf? Would it happen so slowly nothing would notice it?

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