Wellness Messiah with Rimon

How the Interventions Testing Program Can Help You Live Longer (or NOT!) Wellness Messiah with Rimon 36.4K subscribers Subscribe 60 Share 1,044 views Jun 30, 2023 What is the Intervention Testing Program - and should you trust Them? The Intervention Testing Program is a collaboration between 3 research labs that run lab experiments on longevity in mice in different locations. They have strengths and weaknesses. The ITP has 4 major strengths that give them “gold standard” acclaim in longevity research. And 4 major weaknesses that nobody is speaking about. Both are relevant for making conclusions about longevity habits we can follow right now. Brad Stanfield & FISETIN: Shocking Detail and Big Mistake Wellness Messiah with Rimon 36.4K subscribers Join Subscribe 770 Share 19,146 views Jun 20, 2023 In 2022, Dr. Brad Stanfield posted a video in which he explained why he stopped taking Fisetin and Quercetin, two of the most popular supplements in our longevity community. This comes in total contradiction to the expert opinion of other longevity researchers, such as Dr David Sinclair, Dr. Paul Robbins , and Dr James Kirkland. Who’s right? Who’s wrong? I watched the video, and after researching about it, and finding pretty shocking things, I had to post my reply. And today, we’ll do an investigation into Brad Stanfield’s conclusion. We’ll discover: - What are senescent cells and why they matter to your longevity? - What is the number one reason Brad stopped taking fisetin and quercetin? Then, I’ll tell you what I really think about Dr Brad Standfield and his channel. ---------------------------------------------------------------------------------------- ✅ Check Rimon's new updated longevity course: https://wellnessmessiah.com/course ---------------------------------------------------------------------------------------- ✅ Become a channel member on Patreon. Join with $1 & get access to the 10 resveratrol habits & earn an honorary mention in future videos. ✅ Upper levels receive my entire supplement routine & brands (worth $100). https://www.patreon.com/WellnessMessiah ---------------------------------------------------------------------------------------- Study References: https://academic.oup.com/biomedgeront... https://www.nia.nih.gov/research/dab/... https://www.nia.nih.gov/research/dab/... https://www.ncbi.nlm.nih.gov/pmc/arti... https://journals.plos.org/plosbiology... ---------------------------------------------------------------------------------------- ✅ The favourite videos on this channel - playlist: • Longevity Favorites ---------------------------------------------------------------------------------------- The Wellness Messiah podcast is available on Spotify, Apple Podcasts, and Overcast. ---------------------------------------------------------------------------------------- Credits: Scott Buckley Disclaimer & Disclosure: The information in this video and/or at this channel is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. It is intended as a sharing of knowledge, educational and information from the research and experience of Rimon, who encourages you to make your own health care decisions based upon your research and in partnership with a qualified health care professional. Rimon is not a medical doctor. If there is a contradiction between the advice here to your doctor or local authorities, always go with the doctor and the authorities. Statements made, or solutions suggested in this video and/or at this channel are not intended to diagnose, treat, cure, or prevent any disease. Chapters View all Wellness Messiah with Rimon 36.4K subscribers Videos About 242 Comments rongmaw lin Add a comment... @WellnessMessiah Pinned by Wellness Messiah with Rimon @WellnessMessiah 11 days ago (edited) Your advice - Should I do data interpretation now or wait for the full study? Subscribe here: https://www.youtube.com/channel/UCG0nRYyl8V8wCqyc5f6hMaA?Sub_Confirmation=1 12 Reply 12 replies @joannsmith9 @joannsmith9 11 days ago (edited) I’ve said it before and I’ll say it again—YOU HAVE THE BEST BRAIN OUT THERE IN THE THE LONGEVITY FIELD ! Thank you so much for figuring this stuff out and sharing it with us. I love you. 27 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @miketout @miketout 11 days ago Impressed with your approach to addressing this topic logically without any individual disparagement. Appreciate you helping people find their way to the truth. 12 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @henrymroth9455 @henrymroth9455 11 days ago Hi. I am continually amazed by your insights into studies done by other researchers, and how you often find significant issues being overlooked. Well done! 9 Wellness Messiah with Rimon Reply @lucycooper55 @lucycooper55 11 days ago (edited) That was a lot of work putting these interviews and studies together… thank you for shedding light on fisetin / quercetin … I’m going to keep taking it for now 🤷🏼‍♀️ 19 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 5 replies @fahadirshad6996 @fahadirshad6996 2 days ago I have approximately over 60 supplements and drugs including fisetin, quercetin, nmn, resveratrol and spermidine. What i found according to my experience is that nmn has strong results. Fisetin is also effective in increasing oxygen tolerance throughout the body. In fact all of the five longevity supplements do have a positive effects. Remember i m not referring to any lab results, i am all about what i felt or experienced on my own. 3 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @philipmontague6371 @philipmontague6371 9 days ago Thanks Rimon, I was very disappointed and confused over Brad Stansfield’s decission on Fisetin and Quercetin although on balance decided to continue my own regime. So hearing your take on it I agree strongly that accurate data interpretation is vital on which we can all base our personal approach to supplementation 2 Wellness Messiah with Rimon Reply @bromans4862 @bromans4862 11 days ago Brad is too rigid and swayed by every latest study, no matter what it says. He will be changing his mind when the next study says the exact opposite. The fact is that fisetin is proven many times over to be effective. 13 Wellness Messiah with Rimon Reply 7 replies @nikolastojnovic192 @nikolastojnovic192 11 days ago I do apreciate your angle and interperetations very much so. it is of the essence to keep this community (and any other community for that matter ) properly and accuratly informed. i feel your coments and findings are genuine and sincere and that helps a lot. ive learned a lot from you. please go on. 7 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @monnoo8221 @monnoo8221 11 days ago (edited) oooops. My jaws dropped... You are doing great work. Thank you!!! It is this kind of work that makes your channel so trustworthy. You are a genius :)) ...so they claim to made a study in 2018, Stanfield talks about it in 2021 \ 2022, and in 2023 it is still not published ??? Serious academic research works differently (I am trained as a natural scientist, in biology). In a world where publishing is everything, not to publish for 5y means that the persons doing the study long left the organization, and the studies were not at all clear. Also, they refer to a Fisetin hydrogen sulfide study... Interesting part, this hydrogen sulfide. Probably it was a study about provoked senescence. ....and Mr. Stanfield is just a clown. His way of thinking, as revealed in this affair regarding the relation of fisetin and quercetin, has structural deficits and he should not feel entitled to give any recommendation, not even express his opinion on YT. That was not just a small mis-take. He has absolutely no clue about biochemistry. 17 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 6 replies @jgs9911 @jgs9911 10 days ago Rimon, thanks for your work. With regards to Dr. Stanfield, I stopped following him awhile ago as I believe he is more interested in click bait than actual analysis. I have confidence in your data interpretation so please continue the great work. Any update on your wife’s condition? 7 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @davidgifford8112 @davidgifford8112 8 days ago Sorry Brad, as a practicing physician, does what most busy clinical physicians do. Doesn’t read papers, at best they read the abstracts and perhaps the bottom line of the conclusion. These are the good Doctors! I had a local GP who confessed, he never read “articles” he was a qualified doctor! To my point Brad is a master at the shortcut conclusion, hence his frequent change of “personal” practice. He seems to have upped his game, reacting to a single statement on a paper yet to be written. My real point is that all study papers are written to be published, in doing so they need to satisfy the peer review, to do so they often need to “massage” the abstract and conclusions to pass peer review, sometimes to a point where they don’t match there own study data. Of course this assumes that a study like this wasn’t set up to fail by design. Usual tricks: inappropriate and low P study population, under dosing, short duration. Inappropriate markers and peculiar statistical categories. Perhaps the best is “adjusted for cofounders” without identifying what the cofounders were or how they were weighted. Final note Dr Kirkland is perhaps the most experienced researcher into senolytics we have, while that doesn’t make him correct, his informed understanding of senolytic research is discounted at your peril. 1 Wellness Messiah with Rimon Reply @somkiatkraikriangsri7742 @somkiatkraikriangsri7742 11 days ago Great work. Really like what you’ve done so far to present every angles of information:-) 2 Wellness Messiah with Rimon Reply @felicisimomalinao1981 @felicisimomalinao1981 10 days ago Dr. Stanfield is very cautious about spending for supplements that have doubtful effect. Quercetin and fisetin may require large doses that would be waste and reduce our budget for the more important ones. 4 Wellness Messiah with Rimon Reply @fatboydim.7037 @fatboydim.7037 11 days ago Great video 10/10. Keep pushing out content of this quality and your subscriber count my double. 6 Wellness Messiah with Rimon Reply @pestimom6572 @pestimom6572 10 days ago Great analysis. Good brain, good heart. I can't wait for your videos. I was following Brad Stanfield, but his logic didn't seem sound to me and I feel he has an agenda, maybe pro-pharma? I don't know, but it seems that way. I still like Sinclair. His studies are sound and he shares what he takes. When I added fisetin to my liposomal NMN concoction, there was a huge increase in energy, and I had to reduce the dose of fisetin. Definitely feel a difference with it. Thanks for your work. 2 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @m1ker0t3 @m1ker0t3 10 days ago This is my favorite longevity channel! 5 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @carlor.s.4742 @carlor.s.4742 11 days ago No doubt that data interpretation is important along with scientific replicability. All data should be submitted to independent examination(there is far too little of this!). Apart from the effects of Fisetin & Quercetin, IMO the best way to get rid of senescent cells is to do 24 hr, fasts, which I do every weekend. This promotes effective autophagy & as a 79 year old, it is most likely I have a plethora of senescent cells. Maybe autophagy using the body's own processes is more effective than adding exogenous molecules through supplementation, I have lists of foods that supply Fisetin & Quercetin & I try to eat these as much as possible as well. Congrats on your thorough analysis of the science. As for Stanfield, I find him to be somewhat impulsive in drawing conclusions. 4 Wellness Messiah with Rimon Reply @josher3436 @josher3436 5 days ago Enjoyed this take on the issue. Keep it up. Really appreciated your approach. Wellness Messiah with Rimon Reply @wam8290 @wam8290 4 days ago Great video and very insightful as always 😊 thank you. 2 Wellness Messiah with Rimon Reply @gprivat812_my_selection6 @gprivat812_my_selection6 3 days ago Great background information! As there are no risks found (yet?) taking Quercetin/ Fisitin other than spending money on a possibly useless drug, I will take it and wait for more data. Reply @francoistourigny3006 @francoistourigny3006 11 days ago I am happy for once somebody said the word that many peoples think, it’s very frustrating for the consumers to receive contredit confirmation on product he invest and use for a certain time and moneys, thank you. 3 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @____2080_____ @____2080_____ 8 days ago Brad should look into the research from Life Extension who has introduced compounds that allows for body to actually absorb them. Most if not all of these compounds aren't absorbed as capsules. You would likely need to get expensive shots to make them work and even then, the absorption issues are still there. Reply @peterz53 @peterz53 11 days ago Dr. Brad is too young to worry about SC. I'm in my 60s and based mostly on Dr Kirkland's work i will continue periodic fisetin use. Low toxicity. 5 Wellness Messiah with Rimon Reply 1 reply @patrak3606 @patrak3606 11 days ago (edited) Quercetin was recommended by my oncologist for a bronchial cough/cold I couldn't get rid of due to having cancer and a weakened immune system but, after taking it for about 10 days it I was completely healed. Nowadays, I take it once I feel a cold coming on and it kicks it in the bud, never having to deal with ever feeling sick. 6 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 4 replies @TomLeser @TomLeser 11 days ago What’s the ideal frequency for taking these? I’ve seen some reports that taking these infrequently was a better approach. A couple times per week for Quercetin and as little as one or two per month for Fisetin. I can’t remember where I saw this but Rimon if not for you I’d be taking too much Resveratrol daily until I saw your video so I thought you might have insight into quercetin and fisetin frequency. 4 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @yuvalkapellner2551 @yuvalkapellner2551 5 days ago Quercetin has other benefits aside acting as senolytic. It tackles nad+ depletion from a different angle of that taken by NR or NMN by affecting cd38 levels and act as attenuator. So that alone is a good reason to take this supplement. The claim is that in high dosage it also could operate as a senolytic and was shown to act as sirt6 activator. 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @dwintablet @dwintablet 11 days ago I think Brad also states he’s around 30 or 35 so it doesn’t make sense for him to take them personally since senescent cells do not build up until older. Age matters. 21 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 8 replies @jasonbromano @jasonbromano 9 days ago Another great video, Rimon! I also like Brad Stanfield quite a bit, in fact I added creatine and collagen peptides to my supplement routine based on his videos. However, like anyone, he's not perfect and sometimes gets it wrong. I find his videos about why he stopped taking things less convincing than his other ones which are usually really good. Like his resveratrol video which you replied to earlier. Here with fisetin and quercetin is another example of how he incorrectly interprets data. And his reasoning for why he stopped taking quercetin is particularly bad - it's a different molecule than fisetin to begin with. But setting its senolytic properties aside, it is an iron chelater, which is critical because excess iron hurts your health and longevity, is a zinc transporter, which is important because zinc needs to cross into cells to help your immune system, and it is a sirt6 modulator, meaning it stimulates or represses sirt6 activity depending on the circumstances. So deciding whether to take quercetin based on how its senolytic properties compare to fisetin seems ill reasoned. And fisetin has good things going for it besides its ability to eradicate senescent cells. To do that you need to to the high dose pulse protocol that Dr. Kirkland is testing. But low dose may induce cells to clean themselves by eliminating old or damaged organelles or other proteins and reduce senescent cell toxins in the system. So you can't even judge fisetin on its ability to reduce senescent cells alone, you have to consider everything. Regardless of Stanfield's videos, I take both fisetin (liposomal form) and quercetin (phytosome). An unexpected result of the fisetin is my skin softening and becoming smoother. Anecdotal of course, but I was very surprised this happened after adding fisetin to my supplements. And when I looked into it out of curiosity it turns out there is some evidence for it improving skin health. Go figure! To sum up, I think Brad Stanfield is a big asset to the longevity community, especially given he's on the side of allowing NMN to be sold even though he doesn't use it, but like all of us, you can't just take his word on anything uncritically without validating his reasoning and conclusions. Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @dan01399 @dan01399 11 days ago (edited) Any chance you could get an interview with the head or a researcher at the ITP? Would be interesting if you’d ask all those questions directly to the people working on those studies. 2 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @Armin-rr9wr @Armin-rr9wr 6 days ago Since it is likely that senolytic cells start accumulating above the age of 50, it is not a big risk to younger people to delay the taking of anti-senolytics compounds until further evidence. Also, there are researchers that hypothesize a delicate balance between senolytic cells and cancer cells that is not yet understood. Wellness Messiah with Rimon Reply @larsnystrom6698 @larsnystrom6698 8 days ago Dr Stansfields stand on quercetin was probably based on that research (Kirkland, perhaps) showed that fisetin was more effective than quercetin. So, if fisetin doesn't work, the weaker quercetin wouldn't work either. This is just my guess. That quercetin works better together with that cancer pharmaceutical might indicate that senolytics work better in combinations. Such as quercetin and fisetin together, perhaps. 1 Wellness Messiah with Rimon Reply @tomgooch1422 @tomgooch1422 11 days ago Dr. Kirkland's observations in the video regarding the lack of senescent cell markers leads me to wonder: 1.How are the senescent cells themselves detected...and characterized? Does one detection methodology fit all senescent cells? 2.Are there degrees of senescence? 3.Can senescent cells definitely NOT be resuscitated? If not, why not? 4.Can senescent cells be typed by origin, i.e., used as organ early warning indicators in their own right? 5. Are there common and predictable epigenetic markers for senescent cells, or are they all unhappy in their own way? Declaring senescent cells themselves the problem seems analogous to a mechanic discovering metal in an oil pan and installing a magnet in the oil filter as a "solution." Some bearing is in trouble. 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @HateDietPepsi @HateDietPepsi 10 days ago A lot of scientists build their whole careers and obtain millions in grant research dollars on flawed theories. When their research eventually produces data that disagrees with their theory they either never report it or throw it out. 2 Wellness Messiah with Rimon Reply @weiminyang7206 @weiminyang7206 8 days ago Fisetin does work for me. I tested by applying it on my right hand and use left hand as control. My age is about twice Brad's. 1 Wellness Messiah with Rimon Reply 1 reply @pistacchini @pistacchini 7 days ago Awesome video 👍 excellent analysis skills 👌 👏 👍 Wellness Messiah with Rimon Reply @stephenwillis9571 @stephenwillis9571 4 days ago Good video but a bit of a tease as to why the study was flawed. I suspect bioavaialability has much to do with it.Curcumin is another good senolytic, and that as huge absorbtion issues. Fisetin, though is not just a senolytic, which is where Stansfield was unwise - the length and breadth of the studies on fisetin are remarkable. Wellness Messiah with Rimon Reply @kenswanston820 @kenswanston820 10 days ago Rimon: In your experience is it normal for a study (being run by ITP?) in 2018 still NOT being published in 2023? Is it due to the study only being started in 2018 and not being completed until recently? If so, how could the 'experts' on fisetin / quercetin risk their credibility by commenting on an incomplete study before it is published? If the target of fisetin / quercetin is removing/recycling senescent cells (in all their varieties), how effective are each of the various types of fasting (8/16, OMAD, 3 day water fast, 7 day water fast) when compared with the two supplements noted? Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @BakamonNO @BakamonNO 11 days ago I'm glad your channel exists 4 Wellness Messiah with Rimon Reply @Letsplay222 @Letsplay222 11 days ago Thanks for the video. As for Dr Stanfield, his channel was really helpful at first. Then all of a sudden he became pessimistic and negative about everything, to the point I didn't feel his channel was useful anymore. Glad I found yours! 8 Reply 2 replies @Kimhjortsbjerg @Kimhjortsbjerg 3 days ago We've always known from the advice of the elderly that there was an effect of eating an apple with(quercetin) or without the skin, so the bottom line in my opinion is don't listen to studies that try to distract you from reality ! It is healthier to eat a whole apple than to peel it. So that effect cannot be removed by a study that has not been published! Reply @waslick11 @waslick11 11 days ago What about grape seed extract which is reported as a good senolitic ? Great Work Rimon.🎉 3 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @walterantosch7133 @walterantosch7133 4 days ago Thank you for your very profound analyses, I really do appreciate it very much. I ordered therefore the 120+ course a couple of days ago, but did not receive it, although I payed the affordable amount. Can you help me, where I can get the access? Again, thank you for your work! Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 3 replies @larrydykes7643 @larrydykes7643 6 days ago 19:47 you circled 2 areas of difference on your diagram but the larger circle does not indicate a difference. Remember the single bond that binds the 6 carbon ring to the rest of the molecule is swivel, so the two representations are equivalent. The only real difference in the two molecules is the extra OH shown on the lower left. 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 4 replies @zengarden4534 @zengarden4534 7 days ago The human body has around 100 trillion cells each consisting of 100 trillion atoms. I think you'll need powerful quantum computers and super-intelligent AI to piece together the puzzle. The problem with these antiaging protocols is that they are based on grossly incomplete understanding of the human body, and it takes only one false assumption to derail the effort or even bring more harm than good. 2 Wellness Messiah with Rimon Reply 2 replies @wmp3346 @wmp3346 9 days ago I take both but not everyday 😊 Wellness Messiah with Rimon Reply @bmm9842 @bmm9842 11 days ago I like Brad Stanfield and he does very good work analyzing the various studies out there - better than most by far. Lots of people jump on the longevity hypewagon and ride it as far as they can citing mice data and seriously flawed human studies. So, my question would be where is the long term, human studies (properly conducted) that show that either fisetin or quercetin provide senolytic benefits? I don't think there are any and that's what Brad says most often. If there isn't solid science around it he's not going to recommend it. He almost always says that it's your choice and if it works for you do it as long as there are no harmful or long term side effects. Mice data is only "interesting" at best. There are an almost uncountable number of tests on mice with various interventions that yielded no result in humans. There's still questions about the bioavailability of fisetin and quercetin in the first place when taken orally. So, let's not misquote Brad here. He says this is why HE stopped taking it. He didn't say you should stop taking it nor did he say it's ineffective. What he did say is that from what he sees of the science, there just isn't enough evidence yet to say it's truly effective. I tend to agree and want to limit my supplement stack to those things that we know are effective instead of making the pharma and supplement companies rich. Also, let's be honest and build in a little "bias interpretation" into our opinions. Brad has nothing to gain from recommending or discouraging the use of certain supplements and drugs. Sinclair and the rest of them often do since they have built a business around selling them. Show me some unequivocal proof and science that this stuff works and I'm all in. Until then, it remains "interesting" to me. 8 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 5 replies @homeontherange733 @homeontherange733 11 days ago I am confused about the comment about losing our only arsenal of defense against senescent cell buildup. Not only are there alternatives, there are free alternatives. Mankind has been fasting for thousands of years. Although not popular with the masses, we have know since the early part of the 20th century about clinical proof of caloric restriction with optimal nutrition. Among the many approaches to finding longevity, caloric restriction (CR) has received a lot of attention in the last few years. The first evidence indicating the benefits of CR date back to the 1930s in studies conducted by Clive McKay, an American biochemist and gerontologist. Most people myself included would love nothing more than to be able to pills as a first line defense against aging. 3 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 3 replies @luckssj @luckssj 11 days ago I am continuing to take it because I know that it works 1 Wellness Messiah with Rimon Reply @MarryPopp @MarryPopp 10 days ago Thank You could you please make a Investigation about the diferente effects about Epitalon and Resveratrol ?! It would be very interesting ,.thank you 🙏fir all your Videos 💝💐🌈 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @grantlikes2sing @grantlikes2sing 5 days ago Thank you for this! Wellness Messiah with Rimon Reply @milenadeltorto7158 @milenadeltorto7158 10 days ago You Rock Rimon! 2 Wellness Messiah with Rimon Reply @christopherzell277 @christopherzell277 11 days ago Isn't it possible that natural homeostasis interferes with supplements ( and drugs)? If this is nearly universal, then 'hit and run' is the way to go. 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @ginacardarella @ginacardarella 5 hours ago Love that you question and breakdown these video Reply @peterraidt5244 @peterraidt5244 11 days ago Well Brad also says Vitamin d3 800iu are enough..so much about his credibility 6 Wellness Messiah with Rimon Reply 3 replies @IrrasciblePoet @IrrasciblePoet 10 days ago And i thought Stanfield was the king of analysis. Reply @jamesjones7138 @jamesjones7138 11 days ago (edited) I wonder why Dr Stanfield would want to take such supplements now, when he is so young. Maybe better to take these things when he is older and the evidence for their effectiveness is more affirmitive. There are other compounds, such as NMN that Dr Stanfield doesn't personally take, but Dr Sinclair does. And I find Dr Stanfield's nay-saying around such compounds, the perfect antidote to the possibility of a blind obedience that could be displayed by some consumers, who could be influenced by Dr Sinclair's superstar status. As a potential consumer myself, monitoring the identity of the supplements that both of the Doctor's agree have undeniable, (evidence based), efficacy, will go some way for me making the right choices and not wasting so much money. Dr Stanfield is a General Practitioner in his country of New Zealand and presumably has to satisfy the governing body of his own profession there and presumably his own conscience, that he doesn't make poor recommendations to his own patients in particular and his You Tube audience in general. Dr Sinclair on the other hand is outside that sphere, in the world of academic research. Longevity researchers like himself, can turn around in the long-run and say, 'hey, evidence doesn't support our premises or early research after all', or vice versa, because this field of Longevity research is still so young. Personally, I am often left 'scratching my head' at the disparity of opinions between clinicians or researchers when the Science is supposed to be the same between all of them. Gerontology and anti-aging research is so fascinating. 1 Wellness Messiah with Rimon Reply @dalebullock4817 @dalebullock4817 10 days ago They also found that spermadine wasn't absorbed so aborted the study. The organization needs be scientifically audited! 1 Reply @Scottlp2 @Scottlp2 11 days ago While I had been giving Sinclair the benefit of the doubt, that ended with his recent behavior re: supp vs drug. 4 Wellness Messiah with Rimon Reply 2 replies @greatmaddyave @greatmaddyave 9 days ago Q:"Should you take these molecules?" A:"I dont know...what do you think?" Reply @howiesfunware @howiesfunware 10 days ago This is the first time I've heard of these other two supplements. Any video on these? 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @lindascott-burney5734 @lindascott-burney5734 5 days ago Fascinating, thank you Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @christopherellis2663 @christopherellis2663 10 days ago I can get quercetin over the counter. I am happy to give fisetin a pass. NMN doesn't interest me. There are other options available 2 Wellness Messiah with Rimon Reply @fredsmit3481 @fredsmit3481 10 days ago I appreciate your views, but how can you quote and trust David Sinclair knowing his controversial recommendation of Resveratrol for humans? Also, Sinclair was instrumental in the FDA banning NMN in order to make a profit. Hopefully the FDA allows NMN to be sold again. In order for me to assess your credibility can you please provide your recommendation regarding resveratrol for humans and your opinion on the FDA ban on NMN. 2 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @greatmaddyave @greatmaddyave 9 days ago So whats the conclusion, should we still take it or not? Reply @DrBradStanfield @DrBradStanfield 9 days ago Hi Rimon, it’s important to note that no clinical guideline suggests using Quercetin or Fisetin. We don’t have any robust human data showing benefit for either molecules, plus the Interventions Testing Program found NO BENEFIT for mice who took Fisetin. I’d much prefer to focus on diet, exercise, sleep, and the occasional supplement that has proven benefits such as creatine. ✌️ 2 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @philippedaudi1056 @philippedaudi1056 11 days ago I will continue to take both Quescetine and Fisetine. That you so much for your very informative videos ad accuracies and the readings of the articles and the rendering that you make of them in your Chanel. BUT, please KEEP YOUR COMMUNICATION CLEAN. No unnecessary and quite "stupid" photographs. THANKS. 4 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @mariagargioni3269 @mariagargioni3269 11 days ago Thankyou for your information. But I am still confuse.🙈 1 Wellness Messiah with Rimon Reply @gunjangupta6690 @gunjangupta6690 10 days ago (edited) Brad Stanfield has a lot more videos that have lot of almost believable misinformation and sensationalism and debate based on no data, bad data, or just professional jealousy against other researches. So refreshing to see you take him out on this piece of sensational misinformation on bad data politely. 1 Reply Wellness Messiah with Rimon · 2 replies @jenxsj3902 @jenxsj3902 11 days ago Thanks Riman. I go crazy with these scientists posting they take something and 5 minutes later changing their mind and then changing it again. Then they put those little irritant disclaimers. This is not medical advice. Go and try to make money somewhere else. 5 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @giovannidominoni @giovannidominoni 10 days ago Well, point is that, until that study is published, we can just flip a coin. We can decide to go for Fisetin and Quercetin or not. Point is, we do not know, as for now, if they work. We need to wait. The only thing we know is that they are safe to take, and that they MIGHT work. So, based on that, everybody can take their decision. The question that arises is: why hasn't the study been published yet? They found problems or mistakes in the study, or maybe the pharmaceutical companies that sell Fisetin are sort fighting it? It would be nice to go deep into this. 2 Reply @dianamayfield5615 @dianamayfield5615 9 days ago I think Brad Stanfield is not trust-worthy. He changes his mind at the drop of a hat... Reply @weiminyang7206 @weiminyang7206 8 days ago Brad is too young to take Finsetin. Wellness Messiah with Rimon Reply @bugsy1254 @bugsy1254 4 days ago Dr. Brad is a bit of an outlier. originally he was very much into anti aging supplements. Suddenly he seeks any excuse to rubbish their use. In my opinion. he is either drawing wrong conclusions or maybe his loyalties lie elsewhere. Wellness Messiah with Rimon Reply @markseagoe4488 @markseagoe4488 10 days ago Finding a data mistake implies that you have the data. So why wait. Oh yes to keep us in suspense so we subscribe. Ok I'll play along.. 😅 2 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @daimster @daimster 4 days ago I used to like Dr Brad but recent year his conclusions of studies has tilted upside down for some reason. I don’t trust him at all any longer. Wellness Messiah with Rimon Reply @marinakudrina5732 @marinakudrina5732 7 days ago Thank you so much. Wellness Messiah with Rimon Reply @dloui5214 @dloui5214 3 days ago the WORD of GOD is the best anti-aging medicine ! HALELUYAH !! 1 Reply @N330AA @N330AA 11 days ago Stanfield just makes contrarian headlines to generate clicks. Then he cherry picks data/studies to support the video title. I've unsubscribed from him recently. Particularly when he singled out one of my comments in his IF video and then misrepresented the study i cited to him. 7 Reply 1 reply @halfmoon26 @halfmoon26 11 days ago I am continuing to take Fisetin along with resveratrol every morning, I think Brad lost credibility 2 Reply @ftmrivas3043 @ftmrivas3043 10 days ago Quercetin oral bioavailability is only 1%. Haha 99% goes out. If given via IV, the half life is less than 10 minutes. Having said that if you take it in food as it’s natural source or as the glycoside then it is more stable hence more likely to provide an effect. The secondary metabolites that are generated can persist in the body for 12 hours, it is possible that they might have a promising effect. 1 Reply @mooinabc1 @mooinabc1 2 days ago No sample of cell with Fisetin and one cell sample with out Fisetin. Reply @gloriagolemboski4515 @gloriagolemboski4515 11 days ago That’s Quescetine not quinoline mistake above 1 Reply @timskolnik3819 @timskolnik3819 10 days ago Stanfield tries to be "epiinformation" as in above the information. He flip flops every other day, in order to be the most cutting edge longevity "expert" which he's proving he's not. I totally understand why David Sinclair blocked him. 2 Reply @pepeponcela @pepeponcela 11 days ago (edited) What Dr Brad is saying is simple: there's no real evidence for fisetin (or if anything the ITP is evidence against its effectiveness), so no point in taking it. I remember seeing some research measuring the presumed potency of the various senolytics and yes, quercetin was a lot less potent than fisetin and others. So Dr. Brad is behaving like a proper scientist: "no evidence, no intake". Others, like that clown Sinclair, will hold on to poor studies on worms from two decades ago, and yet take a risky stance: "I want to believe [fisetin / resveratrol/ snake oil] works based on some petry dish work or magic wand, and will take load on it for giggles - and tell everybody that I'm doing it". The problem with Sinclair is not just that he wants to become rich[er] with nmn and that has always had a financial agenda: it's that his scientific approach to the field is either lacking or absolute trash, edging on irresponsible (like suggesting the antiageing benefits of growth hormone and other reckless claims that can be harmful to health). Another simple point: Brad invites dialogue and conflicting views of existing research... whereas Sinclair blocks scientists that criticise him from his Twitter. Tells you all. I like that your videos are shorter, Rimon, and that you incorporate more of the real players: those doing the actual research or those analysing the soundness of the studies with a critical mindset and eye: in the fight against aging, we may be hurting ourselves (like loading on resveratrol) on the back of hope or poor research. 9 Wellness Messiah with Rimon Reply @davidfullhouse @davidfullhouse 4 days ago Appreciate your rigor, but the whole thing is a bit of a tease! Wellness Messiah with Rimon Reply @AdventureTrust @AdventureTrust 11 days ago Our Dear Messiah, The repetitive phrase "our longevity community" seems desperate for belonging. How are you defining your strange idea "our longevity community"? Are you using this phrase like "nuestra madre de Guadalupe" or "nuestra virgen de discotecas"? We can throw words together and see how they sound but the addition of "nuestra communidad de longevidad" to our lexicon (yes, "our lexicon" IS a thing) reveals how religious longevity science actually is. At the root of religion is money. "The authorities" are keeping an eye on you. Your approach to science is suspicious. And may your mother make certain that your dress appropriately when walking in public or in videos so that you are not caught by "the authorities" being outside of the community. Our Naughty Messiahs get spanked ... they get spanked reeeal baaad by "the authorities." 2 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 5 replies @annewall2968 @annewall2968 10 days ago I became confused by watching Brad Stanfields videos…he’s too contradictory in my opinion and changes his mind too often. He seems more interested in what supplements are right for him at his young age rather than looking at what can help people who are older and would benefit from the correct advice and supplements. I unsubscribed a few weeks ago from his channel. 1 Wellness Messiah with Rimon Reply @stephensuddick1896 @stephensuddick1896 9 days ago I counted four different pronunciations of Fisetin. Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @Austrian_Powers @Austrian_Powers 10 days ago (edited) 9:23 he believes couple of glasses of wine are good for you... any alcohol consumption cuts down one's REM sleep by 50% , good luck with that hyperminimal resveratrol (maybe-benefit...) He just likes wine and wannts a justification... Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @shus5787 @shus5787 11 days ago Any thoughts on carbon c60? 2 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @user-cy1hu7sb2y @user-cy1hu7sb2y 1 day ago Dr. Peter Diamandis is a Longevity Insider. Reply @IrrasciblePoet @IrrasciblePoet 10 days ago Rimon mosif hamon King of fruits Wellness Messiah with Rimon Reply @gloriagolemboski4515 @gloriagolemboski4515 11 days ago Is only 100 mg of Resveratrol doing me any good. Is it to low. I also do take Quinoline. 1 Reply @newdata @newdata 9 days ago this goes under low risks high returns trade Reply @exxzxxe @exxzxxe 3 days ago I used to follow Stanfield, but no more. He is all over the map- sometimes contradicting research; I checked him against peer reviewed, published research to reach my conclusion. Reply @ezilmez1 @ezilmez1 10 days ago I think Dr Stanfield is too quick to jump to conclusions therefore wrong. Reply @ale-wr6xi @ale-wr6xi 11 days ago are you seriously comparing these big scientist with this clown Brad?? 3 Reply @LawnChairGrandMaster @LawnChairGrandMaster 5 days ago two glasses of wine each night = bad....that guy garners no confidence from me. Wellness Messiah with Rimon Reply @resstr1146 @resstr1146 3 hours ago If you’re still promoting Dr. Sinclair , you are suspect to say the least. Reply @jlg3315 @jlg3315 11 days ago some gold standard. any credibility at all? Reply @isa-manuelaalbrecht2951 @isa-manuelaalbrecht2951 8 days ago First you need to know your geno- metabolic type...some medical mushrooms are great..and sorry stopp all to* settle on horror blas* this is totally against messianic thoughts.. Get off those habits..🤨 Wellness Messiah with Rimon Reply @semaaral2498 @semaaral2498 10 days ago First Off All, I appreciate your hard work & Rational investigation. Especially for people like us who have ill people at home & waiting for our help, this longevity news is important. Every investigation is valuable of course but don't know the scientists people who made this research. So don't know what makes them talk like this. Are they 7/24 working for #Life span no idea. Most of the time in this real world "Money Talks" So have to wait for more research. But when It comes to our ( at least I accept him like that) valuable Scientist Dr.Sinclair, I always believed in his studies from day one. He shared his Lab Team and young students working with him. Waiting for their eye investment results 👏 I follow him. Let's say if Dr Sinclair says he is wrong one day, still he has credits on me. Always ready to forgive him😔 But nice to listen to all these efforts. I appreciate. But lately, I read in an article quercetin tablets may work like Alloprinell tablets for People who have High Uric Acid. How true no idea. My husband's tiny arteries are blocked in his kidneys. The doctors said they can't open it. They are so tiny. I'm trying not to send him to Dialysis😌 So far so good, touch wood. Especially after taking NMN 250 mg every day & Resveratrol 250 mg every other day, "see I've listened to you on this subject"🤩 I give him twice a week quercetin. But let's hear from you more. Also don't forget our ages. 65 + we are We aren't young any more. Dr Brad is young like you young so Results will be different in your cases. I follow DrSinclairs father's protocol.😊 He is 82 this year. Wish him Many Happy Returns👏🌹🧿 Thank you for this logical video . God Bless your wife & you🙏🙏🧿🧿 Wishing her a speedy recovery 🙏🌺❤️ 1 Wellness Messiah with Rimon Reply WHY David Sinclair Takes SO MUCH Resveratrol? (Ep. 5) Wellness Messiah with Rimon 36.4K subscribers Join Subscribe 529 Share 14,883 views Jun 17, 2023 If you follow David Sinclair, you know he takes 1 gram of resveratrol every day. This is a contradiction to what he discovered in his studies, and what the rest of longevity studies on resveratrol show. When I discovered that in Sinclair's study, low resveratrol had the best longevity results, the first thing I did - was trying to get Dr. David Sinclair’s response. Did he answer to me? You’re about to find out. In the last part of this resveratrol series, we will try to answer: Why does Dr David Sinclair take 1 gram even though in his studies lower dose worker better for longevity? I’ve gone on many David Sinclair Interviews, and collected for you five segments where Dr. Sinclair touches this critical issue: thy he takes so much resveratrol? And we’ll also conclude this 5-episode resveratrol investigation. ---------------------------------------------------------------------------------------- ✅ Check the new longevity course: https://wellnessmessiah.com/course ---------------------------------------------------------------------------------------- ✅ Check the special deal of habits creation app + my routine for longevity: https://wellnessmessiah.com/app Disclaimer: I'm an affiliate of the company - I trust their product. Buying will support my channel. ---------------------------------------------------------------------------------------- ✅ Episode 1: • RESVERATROL & Dav... ✅ Episode 2: • RESVERATROL & Dav... ✅ Episode 3: • EXERCISE, Resvera... ✅ Episode 4: • RESVERATROL POWER... ---------------------------------------------------------------------------------------- ✅ Become a channel member on Patreon. Join with $1 & get access to the 10 resveratrol habits & earn an honorary mention in future videos. ✅ Upper levels receive my entire supplement routine & brands (worth $100). https://www.patreon.com/WellnessMessiah ---------------------------------------------------------------------------------------- ✅ The favourite videos on this channel - playlist: • Longevity Favorites ---------------------------------------------------------------------------------------- 00:00 Intro 01:19 Joe Rogan Interview 03:46 Speculations 07:42 Peter Attia Interview 15:50 The Power of Nature 18:16 The Counter-Intuitive 21:55 Your 3-Step Plan for Longevity The Wellness Messiah podcast is available on Spotify, Apple Podcasts, and Overcast. ---------------------------------------------------------------------------------------- Credits: Scott Buckley Disclaimer & Disclosure: The information in this video and/or at this channel is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. It is intended as a sharing of knowledge, educational and information from the research and experience of Rimon, who encourages you to make your own health care decisions based upon your research and in partnership with a qualified health care professional. Rimon is not a medical doctor. If there is a contradiction between the advice here to your doctor or local authorities, always go with the doctor and the authorities. Statements made, or solutions suggested in this video and/or at this channel are not intended to diagnose, treat, cure, or prevent any disease. Chapters View all Wellness Messiah with Rimon 36.4K subscribers Videos About 103 Comments rongmaw lin Add a comment... @WellnessMessiah Pinned by Wellness Messiah with Rimon @WellnessMessiah 2 weeks ago (edited) ✅ I've just published today the new longevity course: https://wellnessmessiah.com/course I hope you'd like it 😊 9 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 3 replies @davewhipp5051 @davewhipp5051 2 weeks ago Also, remember DS has cancer in his family, and IIRC on at least one video he said he has inherited a gene for lung cancer so if he knows he has a higher risk of cancer and he also knows high resveratrol has a cancer inhibiting effect then that would probably influence his personal resveratrol dose. 22 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 5 replies @FrederikWasniowski @FrederikWasniowski 2 weeks ago It has been a really interesting series, and a perfect Ep. 6 would be you getting a interview with David Sinclair. I don't know if you have gotten a new camera, there is less stuttering in the video. Keep up the good work, and thank you for a lot of new and interesting facts. 8 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 5 replies @serge_stauffer @serge_stauffer 8 days ago (edited) Great, very insightful series. I have reduced the dosage of resveratrol to what you are recommending. Off topic: are you by any chance planing to look into OPC, as it could have a similar effects like resveratrol, but there are also studies which show, that it could be a senolytic. Reply @selenekranz4061 @selenekranz4061 2 weeks ago Jam packed with great information! Thank you for demystifying a complicated topic! 5 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @mattcummings6131 @mattcummings6131 2 weeks ago I feel like it would be very interesting to see someone take high dose resveratrol everyday for 6 months or so and do biological age test. Followed by 6 months of low dose at every other day. See what differences in aging occurred. 4 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @MarvelousMovieverse @MarvelousMovieverse 11 days ago I started back to take higher dose of resveratrol. This is because I think the effect is mostly on the senescent cells, which you want to neutralize/catabolize. It basically mimic an intermediate fasting of the three to four days… this is likely why, opening mice on high dose, they found their organs were still young… or, at least, I hope Reply @CK-mk3ve @CK-mk3ve 2 weeks ago Love watching these videos especially the series. What subjects are next? Peptides, Berberine, ECGC? Keep up the great work. 5 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @Kabookie-cd8fh @Kabookie-cd8fh 12 days ago A combo of NMN and Res boosts NAD. He believes this is the key to vascular health (referenced in a Harvard video). The higher amount you have, the better outcome for ischemic stroke. He knows the dose is safe. He knows the limitations of his studies. It’s the most studied compound of its type but there are still questions. Reply @biggie9817 @biggie9817 13 days ago DS also has the luxury of getting his blood work done way more frequently than most people could ever even dream of. 2 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @hughjones77 @hughjones77 2 weeks ago It is such a complicated compound! Besides the longevity factors that favor low dose, there are so many other effects. Increased nitric oxide production which has wide ranging cardio benefits and activation of the AMPK pathway are 2 primary ones. These are other benefits that may not move the needle on lifespan, but may affect healthspan. 5 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @toddweikle4270 @toddweikle4270 10 days ago Sinclair believes that resveratrol and NMN work synergistically to extend lifespan. This is the reason why he probably does not care about taking a gram. In Sinclair's analogy, resveratrol is like the accelerator pedal of a car. It helps to activate the sirtuin genes, which then use NMN as fuel to do their work. Reply @AT-xl9db @AT-xl9db 2 weeks ago I think not just cycling Resveratrol but cycling it’s doses would be a good way to go…it similarity with quercetin is uncanny so may be similar approach…. Thank you for all the interesting insights. There are so many other interesting supplements to take, I feel like Brian Johnson on some days, hope it all works out well long term - my blood work looks stellar so far. 😊🤞 3 Reply Wellness Messiah with Rimon · 2 replies @ftmrivas3043 @ftmrivas3043 13 days ago (edited) The main problem of resveratrol is the poor solubility and high clearance. Sinclair know that very well. Talk to any Harvard and they will tell you how they feel about him. Also, it is not synergistic it is additive that’s the other problem. Synergy would be if they are on the same target increasing residence time of the compound on the protein. This is a pathway that he is looking at not a single protein. 1 Wellness Messiah with Rimon Reply @williamx0 @williamx0 2 weeks ago Awesome thanks for all the videos in the series! 2 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @joeblow2183 @joeblow2183 2 weeks ago I am concerned about side effects. One is that it blunts recovery from exercise. I exercise a lot everyday. I’m trying to make progress not maintenance. but Sinclair is apparently too busy working to put in the time I do. He does hot and cold plunge and one or two workouts per week. I don’t want to take metformin either for that reason too. 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @bobmorane4926 @bobmorane4926 2 weeks ago Maybe DS is making an educated guess that if resveratrol seems to have a positive effect on chronic or metabolic issues at high doses, logically it would extend life of those affected by those diseases which seem to be at epidemic levels in humans. But that should also be observed in mice too. If a mouse is fed a terrible diet or made to have cancer, can high dose reseveratrol extend their life vs low dose ? 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @dominicdamata2618 @dominicdamata2618 13 days ago Great stuff! How about a more in depth review on olive oil? You talked about it briefly in a different episode but want to know more. Thanks 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @emil8367 @emil8367 2 weeks ago (edited) SInclair is a doctor, he developed it. If we don't know what is going on, especially if he knew that low portion is for longevity and high is for killing damaged cells then maybe it's about promoting Resveratrol and money 🙂 That's my conspiracy theory. Sinclair is to clever to be not aware of it. Besides he knows how to promote 'his' products. He knows market, how it works. If I had no interest in this I'd never mention how much I take, because it depends on so many aspects ! How he can do it being a professor ? Imagine that ! Awareness is strong attitude of what people do, because sometimes even we know something we treat it as a something normal. He shares information like suggestions/promotion of something (what many Y.Tubers do saying the opposite that it's is not an advice ofc.). Also looking at 4 influencers (are not doctors or dietician or any other kind even, Rimon, you are curious, you dig a lot to check information and that is very useful to discover many unusual things related) related to DNA brand, they claim that they don't work for them. This is so weird. So, strange 'coincidence' 🙂. Their channels are so different and still so similar. They never mention each other 🙂 That shows only how YT influencers work 🙂Recently one of them started taking 2gr of NMN saying it's for fungus. Many of them shows their stacks. These stacks are enormous ! I know one thing, this is anourmous amount of money as well around it. Be careful people. Don't lose control about what you need, especially if you are thin and healthy thinking you will increase drastically your life. Look for natural alternatives of NAD and Resveratrol ! 3 Reply Wellness Messiah with Rimon · 2 replies @jeffreyjohnson7359 @jeffreyjohnson7359 2 weeks ago Brad Stanfield has done videos on resveratrol. He's stopped taking it because of lack of evidence of benefit and evidence of harm. Sinclair has made a lot of money off it, and knows the updated evidence. 2 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 3 replies @davidtempest7175 @davidtempest7175 2 weeks ago Thanks for another in depth analysis. I just add a sprinkle to my red wine after dinner. 1 Wellness Messiah with Rimon Reply @philipchang4747 @philipchang4747 11 days ago I heard that the body doesn’t absorb Resveratrol very well - not sure if the body absorbs the whole 1g that he is taking. Or the body only absorbs 300mg from 1g. Reply @monnoo8221 @monnoo8221 2 weeks ago thank you, very good. towards the end you say, low dose R. works in humans for longevity. Mr Lustgarten, in his YT channel "conquer aging" which is about bio hacking aging, has an episode about R. ... He mentions by citing some papers, that R. is only extending the life of obese mice to normal, not above normal. what do you think? About "cycling"... I pretty much cycle everything, including aspects (micro + macro) in nutrition, types of sources, relative amounts, supplements, on a medium and on the shorter time scale.. I think, this keeps the adaptability of the metabolic system up. Reply @diamond_s @diamond_s 12 days ago resveratrol is rapidly cleared from the body. I think low dose perhaps twice a day might be more reasonable than high dose. 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @rmondave @rmondave 2 weeks ago "May" be better? My bsmeter is beeping on red alert ...Sinclair needs to be called on this. Good work WMessiah. 4 Reply @gloriagolemboski4515 @gloriagolemboski4515 11 days ago Mine is only 100mg resveratrol. Is this worth even taken or should I increase.very hard decisions as everyone including Sinclair seem to contradict themselves. . Reply @ruspola5447 @ruspola5447 13 days ago It’s incredible how much scientist ms are learning about the human body but what I do know is that every few years they change their mind in the efficacy of drugs . What seems safe and effective now may be deemed unsafe in a few years . I wouldn’t jump in the bandwagon , pay huge amounts of money for unproven drugs and potentially subject yourself to harm in the process. You need longitudinal studies to see how safe they are Reply @fvw53 @fvw53 2 weeks ago I would welcome your opinion on right mix (how many grammes) of glycine and NAC / thank you Reply @brettt.stuart3854 @brettt.stuart3854 13 days ago Rimon please answer if spirulina blocks B12 or is it superfood? 1 Reply @markaguilera493 @markaguilera493 8 days ago Is the action of oleic acid on sirtuins the same as that of Resveratrol? Reply @FranciscoLopez-rh6yv @FranciscoLopez-rh6yv 2 weeks ago Well clearly 1g is safe, Sinclair does it, and the superiority of low vs high dose is hardly statistically significant, in fact many studies show a steady improvement in hypoglycemic effects with higher doses. Since the blood sugar is king when it comes to longevity effect, I am sticking w Sinclair on dose 3 Reply 1 reply @moniryousefian8782 @moniryousefian8782 2 weeks ago Could you please share which brand of resveratrol are you taking?! Not all of them are good quality. Greatly appreciated 🙏 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @MrVentrata @MrVentrata 2 weeks ago So.. what is a low dose of resveratrol? How many milligrams? 1 Reply @markfischer3626 @markfischer3626 2 weeks ago (edited) Thanks to your episode 2, I stopped taking high dose resveratrol shortly after I started and now take 100 mg every other day. What do you think of this. https://www.youtube.com/watch?v=Fzl8F4WQfTs&list=PLR0gSPbvQL-INZaSArlXCcrq57L-rN1iE&index=52 I take L-Leucine midday with other longevity supplements not just resveratrol but NMN 250 mg, the recommended salvage pathway R-alpha lipoic acid, TMG and apigenin, AKG 1000 mg. I'm thinking of buying the Sirtuin 6 activator. What is your opinion? I take many other supplements at other times of the day. For building muscle I take at night BCAA and HMB. My muscles have grown huge and strong despite doing no exercise. I'm on OMAD 6 hours on, 18 hours off, mostly keto but not all keto. Also I'm aware of resistant starch and refrigerate any and all of it. It seems to work and got the okay from my doctor. I'm 74 years old and feel like 30. Reply @Sweetp520 @Sweetp520 5 days ago (edited) WHICH is more up to date on the supplement routine.... your high level patron membership info for $10 a month or the wellness Messiah membership for $ 37 ???? Reply @jusufagil5510 @jusufagil5510 2 weeks ago Do you have any opinions or speculations why Dr David Sinclair recently became vegan? 1 Reply @isa-manuelaalbrecht2951 @isa-manuelaalbrecht2951 8 days ago Look what Prof.Dan Burke has to tell us about this very thema!! Reply @warkmard-dw4dw @warkmard-dw4dw 5 days ago Metformin creates a B12 deficiency, and a B12 deficiency causes neuropathy. So it's more than likely diabetic neuropathy is caused by long term metformin use Reply @georgechristoforou991 @georgechristoforou991 2 weeks ago This video doesn't answer the question of the title. Sinclair needs to answer this question. Guessing is not good enough. Reply @arsononemwv @arsononemwv 7 days ago Can you make a video on TMG please! And or methylation Reply @CK-mk3ve @CK-mk3ve 2 weeks ago In the video, Sinclair says that low dose Res. has a tumor promoting effect. That one line scares me away from taking low dose. Thoughts??? Reply 1 reply @jonathanmagic5633 @jonathanmagic5633 13 days ago I'll stick to a glass of Red after work, lol. Reply @Ozeanruderin @Ozeanruderin 13 days ago why not cycling monthly between 50mg and 1000mg? best of both worlds? Reply @gloriagolemboski4515 @gloriagolemboski4515 10 days ago You never answered my question on 100mg. Is this the lowest. Reply @omez23 @omez23 2 weeks ago If low dose resveratrol promotes tumors, does that mean it can cause cancer? Reply 2 replies @jenxsj3902 @jenxsj3902 2 weeks ago Does it mean you wasted time and money for three years by taking so much Resveratrol? 1 Reply @ohfft @ohfft 2 weeks ago (edited) Not so, other research has showed resveratrol combined with leucine has a much higher effect! 2 Reply 2 replies @gloriagolemboski4515 @gloriagolemboski4515 11 days ago Mine is only reservatrol Reply @anitamartini5144 @anitamartini5144 13 days ago 2:16 what an odd, revolting side shown of this guy Reply @megabaneen8057 @megabaneen8057 2 weeks ago high dose Resveratrol makes me poop. Lol Reply @okamsug @okamsug 2 weeks ago There is no scientific study that supports any of the claims made on this compound. None. 1 Reply @off-roadingcars @off-roadingcars 10 days ago Your videos are informative, but man, your points take way too long with all the music and transitions. You could literally give us the entire 45 min video content in 5-6 minutes. It gets too frustrating watching Reply @shus5787 @shus5787 13 days ago Coq10? Reply @Jerry-zf3cn @Jerry-zf3cn 13 days ago Way . . . too . . . much . . . babble. Reply @AB-ws2sj @AB-ws2sj 13 days ago Answer: The profit never had any flies on him. 1 Reply RESVERATROL POWER: Best Foods & Supplements for Maximum Effect (ep. 4) Wellness Messiah with Rimon 36.4K subscribers Join Subscribe 1K Share 28,584 views May 13, 2023 Power. Synergy. Collaboration. That’s how your body works. Every food that you eat matters. Every drink. Every exercise and every supplement. They all work together, as allies, forming a powerful team inside your body to make you healthier and live longer. And some of them, are enemies, neutralizing one another, offsetting the benefit and wasting your money and efforts. We’ve seen that in the previous episode. Therefore, to keep your body young and increase your health and longevity, you must use the power of synergy correctly. The problem, though, synergies between foods, supplements, and habits are very rarely researched or even spoken. And if you take a tiny teeny supplement called resveratrol, popularized by Dr David Sinclair, you’re taking one of the most synergetic supplements known to man. Did you know that resveratrol interacts with other supplements that you take? With other foods that you eat? This mysterious molecule targets different mechanisms depending on what you eat, drink, and which supplement you take with it. What should you do? You’ll see the newest research on that. today, In our investigation, you’ll discover how resveratrol interacts with olive oil, avocado, collagen, green tea, red wine, And with supplements, such as NMN, NR, collagen, glycine, NAC, much more. Let’s cover a critical topic that nobody else speaks about that will help you form the lifelong habits of longevity and good health, right now. ---------------------------------------------------------------------------------------- ✅ Check the special deal of habits creation app + my routine for longevity: https://wellnessmessiah.com/app Disclaimer: I'm an affiliate of the company - I trust their product. Buying will support my channel. ---------------------------------------------------------------------------------------- ✅ Episode 1: • RESVERATROL & Dav... ✅ Episode 2: • RESVERATROL & Dav... ✅ Episode 3: • EXERCISE, Resvera... ---------------------------------------------------------------------------------------- ✅ Become a channel member on Patreon. Join with $1 & get access to the 10 resveratrol habits & earn an honorary mention in future videos. ✅ Upper levels receive my entire supplement routine & brands (worth $100). https://www.patreon.com/WellnessMessiah ---------------------------------------------------------------------------------------- Study References - PDF: https://www.dropbox.com/s/lkblj9nmq49... ---------------------------------------------------------------------------------------- ✅ The favourite videos on this channel - playlist: • Longevity Favorites ---------------------------------------------------------------------------------------- 00:00 Intro 01:52 Olive Oil vs Resveratrol 12:59 Avocado 13:36 Red Wine 16:50 Green Tea 21:40 High Dose Resveratrol 25:33 Berries 26:48 NMN, NR and Resveratrol 30:24 Collagen and Glycine 32:42 NAC (N-Acetyl Cystein) 34:51 Today's Insight 36:22 Practical Guidelines 43:22 When to Take High Dose Resveratrol 46:00 Bonus The Wellness Messiah podcast is available on Spotify, Apple Podcasts, and Overcast. ---------------------------------------------------------------------------------------- Credits: Scott Buckley Disclaimer & Disclosure: The information in this video and/or at this channel is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. It is intended as a sharing of knowledge, educational and information from the research and experience of Rimon, who encourages you to make your own health care decisions based upon your research and in partnership with a qualified health care professional. Rimon is not a medical doctor. If there is a contradiction between the advice here to your doctor or local authorities, always go with the doctor and the authorities. Statements made, or solutions suggested in this video and/or at this channel are not intended to diagnose, treat, cure, or prevent any disease. Chapters View all Wellness Messiah with Rimon 36.4K subscribers Videos About 183 Comments rongmaw lin Add a comment... @WellnessMessiah Pinned by Wellness Messiah with Rimon @WellnessMessiah 1 month ago ✅ Check the special deal of habits creation app + my routine for longevity: https://wellnessmessiah.com/app Disclaimer: I'm an affiliate of the company - I trust their product. Buying will support my channel 18 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 7 replies @davewhipp5051 @davewhipp5051 1 month ago Thanks very much, Rimon. You're obviously very good at reading scientific papers to get useful information, I appreciate your time & effort. Having viewed your earlier videos on resveratrol, I have for some time been taking 1gram on a Monday (cancer protective, I'm 55) then 100mg on Tuesdays, Thursdays & Fridays and none on Wednesdays, Saturday or Sunday. Now I'm considering high dosing for 3 days at the beginning of each month, then keeping to my earlier low dose regime for the rest of the month ?? Will re- watch this videro a couple of times more, there is a lot of information... ;-) I hope your wife's health continues to improve. Dave 9 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 4 replies @jasonbromano @jasonbromano 1 month ago Another excellent video! Very informative. Synergy is something I’ve tried to implement for a long time. One way I do this is by identifying multiple molecules/supplements/foods that activate a given sirtuin, like for example sirtiun 1, and incorporate all of them into my diet and supplement regimen. I know that the studies on this are fairly sparse, but the ones I’ve seen that do look at synergy usually show a positive benefit. So I go with that. Among the ones you mention here I’ve used olive oil for many years, and I definitely take NMN, NR, and NAD+. I don’t drink tea though so I have a green tea extract supplement instead, and I’m very glad there is synergy between the catechins and resveratrol. You mention you’ll be looking at quercetin in the future, might I also suggest curcumin? I know that these two have some degree of synergy, so it might be worth it to look at both. There are some other synergistic pathways that I’ve been interested in lately. One I have mentioned before, nitric oxide. It seems like a critical support function for a lot of things that happen to promote longevity. It even seems to activate some longevity processes directly, hence why I’ve started eating foods high in natural nitrates (leaf vegetables and beets). Another that I’ve started taking an interest in is the gut microbiome, which also seems to be extremely critical for so much related to our health and longevity. Maybe you could look at probiotics in the future too? One other thing that I’m a big fan of is liposomal delivery of molecules to increase bioavailability. Again, the research on this is fairly sparse but it seems to make a big difference in the positive effects of things like resveratrol and also quercetin and curcumin (phytosome delivery). Pretty much any supplement with low bioavailability I try to get a liposomal pill for, so at this point I have a lot of them. Keep up the awesome work! Your videos are so interesting! There is a lot to cover, we’ll never figure out everything, but the journey is fun! Best wishes to you and also in your wife’s recovery – glad she is improving! Keep us posted! 5 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @davidtempest7175 @davidtempest7175 1 month ago This video is next level. It clarifies all the muddy water surrounding resveratrol. 9 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @elliottrubenstein1746 @elliottrubenstein1746 1 month ago Thanks so much. Will incorporate several of your thoughts into my health span routines. 77 and getting older/stronger. 6 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @FranciscoLopez-rh6yv @FranciscoLopez-rh6yv 2 weeks ago By the way thanks for summarizing all those papers, and making it accessible to many folks. Love ur channel. When r u going to do the series on pterostilbene / quercetin / fisetin? Some companies already are marketing pterostilbene as a more potent alterna to resveratrol Reply @monnoo8221 @monnoo8221 1 month ago (edited) did not finish to listen this one completely yet (edit: meanwhile I did) but it is GREAT. I highly appreciate your emphasis on non-linearity and synergistic effects and your work for digging out those few papers. Thank you! If all research would re-focus on a more multifactorial design the whole field would be much more advanced. 7 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @jgs9911 @jgs9911 1 month ago Thank you Rimon. I will be incorporating some changes into our routine. Wishing you and your wife the best 3 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @patrickfinnegan5202 @patrickfinnegan5202 1 month ago Very good presentation thank you kindly for the information. Personally I eat one avocado a day and I usually drink about one shot glass of olive oil with it. I also drink green tea and I also drink this chicken bone broth it also has turmeric and ginger in it every day. Also I try to eat as many blueberries as I can when they’re in season and strawberries. I think now after watching your video it might be important to supplement with resveratrol . I also take a NAC supplement along with a few other supplements as well. Longevity is starting to move forward in a very good direction and I appreciate the information. Please keep up the good work! Thank you kindly! 3 Reply @DT-lf2up @DT-lf2up 1 month ago Many different multi-angle and multi-directional aspects were taken into consideration. Good work! 7 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @joeblow2183 @joeblow2183 1 month ago Restored my interest in taking resveratrol again and new insights. What a great report. Thank you! 6 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @localchat112 @localchat112 1 month ago (edited) I like your strategy. I think resveratrol will not work without balance with other antioxidants. Nature loves balance! There are hundreds of different herbs, fruits, vegetables. If not fresh, but in dried form. The amount of each (dosage) is less important, then variety. Better to eat 10 mg each of hundreds antioxidants then 1000 mg of resveratrol. 6 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @David-br7xq @David-br7xq 1 month ago Very good and clear insight. Thank you! Much easier than the last one which was good too but a bit fast for my taste. It is very important to have someone wise like you that can bring light about the new studies and find a way to help applying them. Reply @misswellness9595 @misswellness9595 1 month ago Top notch info, as usual! 9 Wellness Messiah with Rimon Reply @christopherroantree5542 @christopherroantree5542 2 weeks ago Initially I was rather concerned by the heavily and almost obsessive criticism of the Dr Sinclairs use cases/dosage for resveratrol as there may have been a personal research case for his high dosage we simply do not know as he was not advocating people do this. However this video/lecture on synergy is really really good, well done it triangulates a pretty diverse roadmap of application that people can choose in multi faceted ways from supplemental to dietary habits. Definitely something to take note from. Thank you Reply @lamloc5068 @lamloc5068 1 month ago living balance is the key of health, good habits should be in your lifestyle. thanks for sharing and have a good health! 2 Wellness Messiah with Rimon Reply @9999classy @9999classy 3 days ago Amaaazing session Full of findings Definitely will get your deal once I am back home 👏👏👏 Reply @russellsaunders9122 @russellsaunders9122 1 month ago Hi Rimon. Thank you for your great content. Such amazing knowledge. Could you help me. How long after an intense workout session should I wait before taking Resveratrol? Thanks again! 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @joannsmith9 @joannsmith9 12 days ago Rimon. Can you please address something that I’ve never seen addressed by anyone else TO THE EXTENT OF PROVING IT ONE WAY OR ANOTHER. I’ve heard doctors claim that when you grind things into a FINE FLOUR (like wheat) you change the molecular structure of it. This seems like it would be pretty straight forward to determine but all I hear are the presumptions that it might be taking place when you grind things into fine powders or flours. Thanks—I love your brain ❤️🙏🏻 Reply @imrippinit @imrippinit 1 month ago (edited) I saw in a paper somewhere that high dose Quercetin suppressed Sirt 6. It was in research where they were seeking compounds to activate Sirt 6. It may have been the scientist who discovered that Fucoidan was the most potent Sirt 6 activator. I can’t remember her name, but she is an advisor for donotage I’m in a holding pattern with Quercetin at the moment, but I feel like I am missing out! 3 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 6 replies @selenekranz4061 @selenekranz4061 1 month ago Great info - thank you! However, I’m not sure how to proceed. I am 68 years young:) exercise daily, eat a good diet, at a good weight (5’4”/120#) given the new evidence. I’m thinking that I may be taking too many supplements too frequently - daily bio - Fisetin, bio Quercetin, Resveretrol, Pomegranate, among others… would appreciate some thoughtful direction for the optimal daily protocol. Many thanks! 1 Wellness Messiah with Rimon Reply 1 reply @pjaworek6793 @pjaworek6793 1 month ago (edited) Thank you! Rimon, how's your sws sleep when you start eating late? Mines trashed and improves when i do breakfast early. I'm going to move resveratrol to lunch but what about olive oil? I like to put it in my morning greens/supplement drink. How about taking grape seed extract with the resy? That's what ive been doing, no ecgc for me (terrified of the liver and prefer to save it for curcumin). Elderberry extract in place of the blueberry/blackberry and drink blackberry, elderflower, blueberry and lignon berry syrups in water all day. Reply @andynicoll8566 @andynicoll8566 1 month ago A lot to "digest" here (lol). I'm taking most of what you talked about here, my latest blood tests would tend to support these benefits. My Md. said "keep doing what you're doing it seems to be working". If you're taking NMN you're likely taking TMG (trimethyl glicine). Is this not a source of glycine? I wondered about cycling low dose and high dose. I may try an occasional high dose. 4 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @macalex101 @macalex101 1 month ago Thanks. Very informative as ever. Much appreciated 5 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @lauradivittorio1014 @lauradivittorio1014 2 weeks ago (edited) Hi! I'm Italian and live in Italy. I put extra virgin olive oil and red onion practically everywhere, and garlic too. Especially in tomato sauce. We eat it very often. 1 Reply 1 reply @courtneybrown1698 @courtneybrown1698 1 month ago One of your videos (that did a deep dive on low vs high dose resveratrol) provided a formula for calculating the dose relative to someone's weight. Can you provide a time stamp for that info and the title of said video? Or would you mind telling me here? I've been relistinging in an attempt to find it but haven't been able to yet. Reply @lucianopacheco2008 @lucianopacheco2008 1 month ago (edited) Excelent videos, thanks for sharing your hard work. I have a question about other supplements that I have read a lot about. Magnesium, Curcumin and Creatine. What are your thoughts on those? Also, what do you think about taking NAD+ supplements instead of NMN (very expensive in Brazil)? 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @j4s0nm1cha3l @j4s0nm1cha3l 3 weeks ago (edited) Hi Rimon. I want to ask and perhaps propose an idea. What if we put 100mg resveratrol in 500mg capsule, and add perhaps c8 mct oil, or maybe olive oil. And then capsule it and take it maybe after big meal. What do you think about it? 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @EsaiasP @EsaiasP 1 month ago Now I am more confused, but on a higher level. 33 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @enaudeni @enaudeni 1 month ago Wow this is a brilliant episode. Reply @sooooooooDark @sooooooooDark 1 month ago what i still dont understand is why ppl never mention olive leaf powder its dirt cheap here what chatgpt thinks about it: Q: how much polyphenols in 5g olive leaf powder. how much polyphenols in the highest polyphenol olive oil 5ml A: The amount of polyphenols in 5g of olive leaf powder can vary depending on several factors such as the type of olive tree, its growing conditions, harvesting time, and the method of processing. However, a study published in the International Journal of Food Sciences and Nutrition reported that the total polyphenol content in olive leaf powder ranged from 90 to 144 mg/g of dry weight. Therefore, 5g of olive leaf powder may contain between 450 to 720 mg of polyphenols. As for the amount of polyphenols in the highest polyphenol olive oil, it is difficult to provide a specific value as it can vary depending on the brand and the method of production. However, some studies have reported that the polyphenol content in extra virgin olive oil can range from 50 to 800 mg/kg. Assuming the highest value, 5ml of the highest polyphenol olive oil may contain up to 4 mg of polyphenols. _____________________________ yea i know olive oil is also oleic acid, but just from a sheer polyphenol perspective its extremely obvious which supplement to take 4 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @nemanjababic7141 @nemanjababic7141 3 weeks ago What is a better source of Resveratrol? I am currently using micronized 99% transveratrol powder as Dr. Sinclair suggests. But I found new merchants that sell in lower doses via more natural extracts such as japanese knotweed (polygonum cuspidatum) and red grape skin. Reply Wellness Messiah with Rimon · 1 reply @frolicsomgaiety @frolicsomgaiety 1 month ago This guy fkn rules 3 Wellness Messiah with Rimon Reply @gloriagolemboski4515 @gloriagolemboski4515 3 weeks ago What is considered low dose and is that daily. Thank you for you kindness and patience. Wellness Messiah with Rimon Reply @georgezibilich4975 @georgezibilich4975 1 month ago Have you checked the amount of arginine in your collagen supplement? In the past, you have warned about taking too much arginine. The collagen supplement that I have has a large amount of arginine. 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @Zues64 @Zues64 6 days ago I'm kinda new to this longevity lifestyle thing. WRT to Reservatrol, I'm taking 1 g of NMN daily. I listened to Dr Sinclair's 2023 supp update on YT and see he's taking 1g of Resveratrol as well. Is this healthy? At what point does the dosage of Resveratrol turn from health to deadly per the study you cited here? Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @Sweetp520 @Sweetp520 6 days ago Would love to hear about balancing women's hormones ...over 40 If you have gathered any info . THANKS 🙏🏼 Reply @KatSchlitz @KatSchlitz 1 month ago Did this video cover what is low dose Resveratrol vs high dose? What are the different dose amounts? Perhaps I missed it, but I am not easily finding it. Thanks for any help all 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @kiramiftari9486 @kiramiftari9486 1 month ago (edited) I see Sinclaire’s grift keeps on living… amazing! 1 Reply 1 reply @joannsmith9 @joannsmith9 1 month ago (edited) Rimon—I told you that you had the brightest mind in the longevity field—and you just proved it again!! Do you have any opinion on goat cheese and longevity! I can’t wait for the David Sinclair response video Yes, there is a God—his name is Jehovah What is the meaning or purpose of life—to honor and glorify our creator who sooo wonderfully created our marvelous bodies. I pray your wife is getting stronger everyday. 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @BakamonNO @BakamonNO 1 month ago Thank you for all the valuable information. What do you think about resveratrol and polyphenols in dark chocolate? 3 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 3 replies @yeba2b @yeba2b 1 month ago I have resveratol in powdered form . Can i put it in red wine or olive oil? Or if i have a salad with olive oil, would it be better to pour resveratol over the salad? Reply @binyam28 @binyam28 1 month ago Very informative, Why not just eat red grapes or raisins instead of drinking wine ? 4 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @kaidensandoval2104 @kaidensandoval2104 1 month ago hello sir can you make a video about astaxanthin? i want to know more about it. thank you 2 Reply @shouting252 @shouting252 1 month ago (edited) Is it okay for someone younger (30s) to take 1g of mnm? Wouldn't it interfere with the natural formation of nad in the body? Is it better to take nmn every other day? 3 Reply 1 reply @markaguilera493 @markaguilera493 8 days ago Can red wine be replaced with balsamic vinegar or grape juice? Reply @JenP2776 @JenP2776 1 month ago Cannonau is a wine that has the highest level of resveratrol. 5 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 6 replies @fishnski9211 @fishnski9211 2 weeks ago I've taken 10mg astaxanthin and 1000 mg NAC with Glycine and now 250mg on Nmn everyday...I've added R Alpha Lipoic acid and tumeric everyday as well..is that too much..am I back firing and doing more damage than good?...should I go every other day maybe,?...Alternate?...Thx in Advance Reply @Sweetp520 @Sweetp520 6 days ago LOVED IT ......DONE !!!! THANK YOU . New subscriber🙏🏼 Reply @nadeemkhanftii @nadeemkhanftii 1 month ago how much berries blue and black can be consumed daily to get the best effect with resveratrol Reply @TheBwithers @TheBwithers 1 month ago Also synergy with low dose leucine and ginseng. Low dose leucine 1.1g is low enough to lower sirt activation threshold but not high enough to activate mTor. See Zemel et all human studies 1 Reply @Sandy-bm9qc @Sandy-bm9qc 1 month ago At age 70 I started taking resveratrol 300 mg. 4 days a week (capsules) and 1 GM nmn daily ( capsules). My question - is 300 mg. Considered a low dose considering my age and capsules- thinking less absorption of resveratrol via capsules?? Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @FranciscoLopez-rh6yv @FranciscoLopez-rh6yv 2 weeks ago It seems like the data is not very solid (statistically ) for asserting low dose resveratrol being better for longevity. The more extreme stress response will slow cell division even more, more similar to caloric restriction it appears, from the data u showed I would'nt be as assertive on the superiority of low dose vs high dose Reply @rmondave @rmondave 1 month ago 3 to 5 hours is not a short vid.😂😂😂 Reply @BryanDalleStelleOfficial @BryanDalleStelleOfficial 1 month ago Hi, which matcha grade is better for longevity? 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @TheBwithers @TheBwithers 1 month ago What about turmeric? Reply @gloriagolemboski4515 @gloriagolemboski4515 2 weeks ago Still have no idea what a 83 year old woman should be taken dosage of it even though sounds like Sinclair doesn’t take it now. You guys have made one product so confusing. Reply @kenswanston820 @kenswanston820 1 month ago Have you seen any studies that show how to reduce Coronary Artery Calcium? My CAC scan was just over 1000...NOT good! 2 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @gloriagolemboski4515 @gloriagolemboski4515 2 weeks ago I got a like but still don’t know the proper dose and is it daily of Reveratrol. I’m doing what he said ioomg daily. Reply @HarpreetKaur-dw2me @HarpreetKaur-dw2me 1 month ago 🙏👍🏻🌷 3 Wellness Messiah with Rimon Reply @TheBwithers @TheBwithers 1 month ago Resveratrol has poor solubility in olive oil. And for green tea why not just have matcha? That way you are injesting everything. What do you think about black elderberry for sirt6 activation? 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 4 replies @perfectworldofentanglement152 @perfectworldofentanglement152 3 weeks ago At 38:00 , wont Theanine do the same trick? Reply @tonibalnig8009 @tonibalnig8009 4 weeks ago Hi, what brand of resveratrol you would recommend? 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @gloriagolemboski4515 @gloriagolemboski4515 2 weeks ago Why can’t you say what amount your calling low and high dose and how many times a day for how long. Reply @bolunixan @bolunixan 1 month ago Need time stamps 4 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @ohfft @ohfft 1 month ago What colour should reveratrol powder be? 3 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @alterego151 @alterego151 3 weeks ago 21:52 That could be due to gunshot wounds mice suffered Reply @annadrozhinski4410 @annadrozhinski4410 1 month ago Hi Rimon. How is it possible to get in touch with you. I would like to get your professional advice & consultation Tnx Ann 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @overcome.podcast @overcome.podcast 1 month ago why not get the polyphenols from elsewhere, I take citrus bergamot, with 55% polyphenols 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @lungarotta @lungarotta 4 weeks ago Do you take resveratrol every day? 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @riccohofmann8761 @riccohofmann8761 1 month ago Hey Rimon, How can i become a client of you? Apreciate you answer 👍 4 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 4 replies @shus5787 @shus5787 1 month ago 👌 2 Wellness Messiah with Rimon Reply @christopherellis2663 @christopherellis2663 1 month ago I haven't eaten any plants for a year. 😅 Wellness Messiah with Rimon Reply 3 replies @okoiful @okoiful 1 month ago would love to see a 5 minute version of this.. without all the small talk.... 2 Wellness Messiah with Rimon Reply @barbswerdfeger8672 @barbswerdfeger8672 1 month ago What amount is small of resveratrol 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @philippedaudi1056 @philippedaudi1056 1 month ago What about Glynac? 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 3 replies @ammalealaura8923 @ammalealaura8923 1 month ago Clove is the best 3 Wellness Messiah with Rimon Reply 1 reply @PedroGuzmannimbus @PedroGuzmannimbus 1 month ago 150 mg is low dose? 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @sooooooooDark @sooooooooDark 1 month ago yea well...allegedly green tea is all great n all but man...even VERY low dosage (0.5g matcha powder) taken in the morning mess with my sleep the coming night rather take egcg supplement (which does contain caffeine itself but oh well) really cba with caffeine, such a shitty compound (maybe its got therapeutic effect every once in a while like high dose senolytics but other than that.....no thanks) 3 Wellness Messiah with Rimon Reply @paulchapman411 @paulchapman411 2 weeks ago Resveratrol makes me sick 1 Reply @gloriagolemboski4515 @gloriagolemboski4515 1 month ago Does his fast talking voice with that accent confuse and annoy anyone els3 but me. I can’t take it. 2 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @gloriagolemboski4515 @gloriagolemboski4515 3 weeks ago It is not the accent as much as you talk so fast. I like your information but you don’t have to talk that fast. Please. Reply @nadeemkhanftii @nadeemkhanftii 1 month ago you lost me a long time ago Reply @LenGebase @LenGebase 1 month ago The analysis borders on being absurd. Med diet does not equal olive oil Reply 6 replies @Dick-E @Dick-E 1 month ago I downloaded the app but I don't see your protocol in it? What am I missing? 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply he First Day of the Stroke & PEPTIDES for Longevity Wellness Messiah with Rimon 36.4K subscribers Join Subscribe 333 Share 4,318 views Apr 29, 2023 Today, I will tell you about what happened on the first day of my wife’s stroke. It’s a very unusual experience. And we’ll delve into peptides for longevity, as a consideration of your longevity strategy. What are “peptides”? What’s important to know when using them for longevity? ---------------------------------------------------------------------------------------- ✅ Patreon: https://www.patreon.com/WellnessMessiah ---------------------------------------------------------------------------------------- ✅ The favourite videos on this channel - playlist: • Longevity Favorites ---------------------------------------------------------------------------------------- The Wellness Messiah podcast is available on Spotify, Apple Podcasts, and Overcast. ---------------------------------------------------------------------------------------- Credits: Scott Buckley Disclaimer & Disclosure: The information in this video and/or at this channel is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. It is intended as a sharing of knowledge, educational and information from the research and experience of Rimon, who encourages you to make your own health care decisions based upon your research and in partnership with a qualified health care professional. Rimon is not a medical doctor. If there is a contradiction between the advice here to your doctor or local authorities, always go with the doctor and the authorities. Statements made, or solutions suggested in this video and/or at this channel are not intended to diagnose, treat, cure, or prevent any disease. Chapters View all Wellness Messiah with Rimon 36.4K subscribers Videos About 79 Comments rongmaw lin Add a comment... @WellnessMessiah Pinned by Wellness Messiah with Rimon @WellnessMessiah 2 months ago (edited) Two options to support my channel: ✅ Patreon: https://www.patreon.com/WellnessMessiah ✅ Buying this app with a bonus from me: https://wellnessmessiah.com/app 2 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 5 replies @LenkaSaratoga @LenkaSaratoga 1 month ago You are a very solid person, and a super husband. You literally saved her life with your correct actions. Wishing you guys health and happiness! 10 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @tom7471 @tom7471 2 months ago How wonderful that she is at home. She must feel so good about that and that can effect her recovery a great deal! Best wishes. 11 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @naijaman6639 @naijaman6639 2 months ago I wish your wife continued progress as she recovers. I enjoy your channel and I hope it grows. You should have far more subscribers. Best wishes. 8 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @CamiloVergaVideos @CamiloVergaVideos 1 month ago What a story, Rimon, impressive. It's good that your wife is recovering. She has you by her side of her so she can lean on you with your knowledge and love. I hope it continues to improve every day! 5 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @prscribner1 @prscribner1 2 months ago (edited) Thank you for sharing this story. Honestly, it makes me so angry. As someone who has spent their career supporting those with rare and serious diseases and teaching them to be powerful patients strong advocates for their best healthcare, I applaud your proactive approach. So often I have seen patients trust doctors completely, without pushing hard and trusting their own experience and gut. Patient centered care is the gold standard, and that means doctors really listening and trusting patients and their caregivers as a critical part of the healthcare team. Doctor's need to have more humility...this will lead to better outcomes. 14 Reply Wellness Messiah with Rimon · 2 replies @rhondajansenvanvuuren392 @rhondajansenvanvuuren392 2 months ago Best wishes to you and your wife in the recovery process. It is beautiful to clearly see your love for her. 7 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @pjaworek6793 @pjaworek6793 1 month ago Thanks for the update. This makes me tear up each time because I know we're all vulnerable to something devastating like this. Thank you for being strong and showing us how to do so! 4 Wellness Messiah with Rimon Reply @veraarena1583 @veraarena1583 2 months ago Praying for your wife’s full recovery and for God to help you to maintain your high level of dedication and energy to deal with what is yet to come. 5 Wellness Messiah with Rimon Reply @virgilkirschner5717 @virgilkirschner5717 1 month ago Thank you so much for your information. So happy to hear your wife is progressing back toward Total health. You are such a blessing to so many people. 5 Wellness Messiah with Rimon Reply @misswellness9595 @misswellness9595 2 months ago Thank God, your wife, has such a strong advocate for her! 6 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @user-sz3kj2uj6x @user-sz3kj2uj6x 1 month ago I think you pointed out, you have to advocate for those experiencing the healthcare system. Making such efforts they are often able to get the system to provide better care. I think Dr"s are willing to go the distance if people are highly motivated to be very involved in their treatment and recovery. Lucky you had good success and continue to follow it up. You are inspirational for your wife and those that follow your channel. 5 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @dan01399 @dan01399 2 months ago (edited) It’s impressive to see how you literally saved her life! Have you also looked or researched to potentially add Cerebrolysin to speed up the recovery process? Hoping for a quick recovery, all the best! 4 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @priteTube @priteTube 1 month ago My wife had two cardiac arrests. She lost most of her vision and doctor said nothing to be done. I did a lot of research myself and found oxygen therapies. We have done both HBOT and EWOT and there are improvements on her vision. 5 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @SergeantFunkDan @SergeantFunkDan 2 months ago Godspeed continued healing to you both! 3 Wellness Messiah with Rimon Reply @psylinx @psylinx 2 months ago It is now been over three years since my stroke and I'm doing pretty well actually. I communicate pretty close to how I used to except that. I have to use adaptive equipment when it comes to putting stuff down on paper or on a screen. Other than that though I have almost everything else back. I'm actually able to do a little bit of poetry too something I used to be at least somewhat okay with doing. I can writing again and am working to possibly do some other things that may help everybody. George Davis 8 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @matthewwaring1911 @matthewwaring1911 4 weeks ago (edited) Your videos have been a wonderful help to me, especially your breakdown of resveratrol “multi personalities”. I wish your wife and you a quick and speedy recovery. 2 Reply @asgardian001 @asgardian001 2 months ago (edited) Thanks for the video. All the best for your wife’s recovery. I had a stroke at the age of 49. Had left arm weakness, and took 900 mg of aspirin straight away as I suspected that I was having a stroke. In retrospect the hospital said that this was not such a great idea as if I was having a stroke it could be due to a burst blood vessel as much as it could be due to a clot so the aspirin could have made it worse. The hospital was really responsive in taking me in straight away and checking me over but sent me home after a CT and said they couldn’t find anything. I thought perhaps it was a pinched nerve in my brachial plexus perhaps as I had been working out the night before. Fortunately the hospital had organised an outpatients appointment for me to have an MRI 2 days later at which point they found a couple of clots on my right hemisphere. Yes I had had a stroke and by that stage I also had some left leg weakness. Ultimately I was found to have a PFO and had this closed up some months after the stroke. I hadn’t heard of a thrombectomy until your video tbh. My recovery was actually pretty good and I didn’t really have any residual problems besides some nerve pain occasionally along my left hand side and a little left hip weakness. That was a couple of years ago and now I am doing really well. Anyway not really sure why I wanted to share all this, perhaps just some catharsis. Wishing your wife the very best❤ 4 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 3 replies @emil8367 @emil8367 1 month ago Rimon, quick recovery to your wife ! I hope all will be fine and even better 2 Reply @sofiamurgado606 @sofiamurgado606 4 days ago Thank you for sharing! Your wife must be so proud of you for staying proactive in the midst of such a challenging situation. Blessings to you both💛 Reply @kimshiles1579 @kimshiles1579 13 days ago It’s so fantastic you love your wife and went with your instincts to advocate and pay attention. Blessings to you both. 1 Reply @Schu2505 @Schu2505 8 days ago I had a stroke 2 years ago, which left me paralyzed on my left side. I've made a full recover after lot of physical work. I recall our visit to the coffee shop in the wheelchair, so your story made me cry. My doctor told me about peptide injections in longevity clinics. It's a very interesting area of study. I used used ChatGPT-4 to research to topic - sharing: Longevity research has found peptides to be a promising avenue in anti-aging treatments. Peptides are smaller units made up of amino acids, which are the building blocks of proteins. They have a variety of roles in the body, such as acting as hormones, enzymes, or neurotransmitters. This is due to their ability to bind to and activate receptors on cells, allowing them to exert various effects. There are many types of peptides, each with its unique function. For instance, some peptides can increase collagen production, improving skin elasticity and reducing wrinkles, while others can boost the immune system or increase muscle mass​1​. Peptides interact with two main types of receptors: G protein-coupled receptors (GPCRs) and enzymes. GPCRs, found on cell surfaces, activate when a peptide binds to them, leading to changes in cell function. For instance, GPCRs can stimulate the production of enzymes, hormones, or proteins. When peptides bind to enzymes, they can increase or decrease the enzyme's activity, affecting processes like collagen production or cell growth​1​. Unlike hormones, which are larger and can have systemic effects throughout the body, peptides are often localized to a specific area, affecting only nearby cells. This localization enables peptides to be designed for very specific effects in the body, making them useful in various treatments. Peptides can supplement hormones, for example, by increasing hormone levels in cases of deficiency or targeting specific receptors not affected by hormones​1​. A variety of peptides have been studied for potential use in anti-aging treatments, including: Growth hormone-releasing peptides (GHRPs), which stimulate growth hormone release from the pituitary gland, aiding in muscle growth, fat metabolism, and bone density improvement. GHK-Cu, a copper peptide shown to stimulate collagen production, reduce wrinkles, and promote wound healing and tissue regeneration. PKC Inhibitors, peptides that bind to Protein kinase C (PKC), an enzyme involved in cell proliferation and death, to help prevent cell death and promote cell proliferation. BPC57, a peptide that reduces inflammation, stimulates wound healing, and promotes cell proliferation​​. While there is still much to learn about peptides' potential use for anti-aging, the available evidence suggests they can be beneficial in reducing aging signs. The research indicates a hopeful future where peptides play a vital role in more effective, holistic, and safer anti-aging treatments. Reply @gunner8601 @gunner8601 2 months ago All the best to you and your wife 😊 3 Wellness Messiah with Rimon Reply @chrisfos @chrisfos 1 month ago Peptides I believe are 100% the way forward for medicine. It’s a huge growth area within research. I have been involved in peptides for 13 1/2 years and had my business U.K. Peptides for 11 years. Very difficult area due to legislation or even lack of it. We can’t promotors or talk about them to general public. But we have just agreed to work with a doctor who had now been given the permission to prescribe un-licensed medicines when no other suitable alternative is available. Good luck. Very good contents and knowledge. Reply @MyMy-tv7fd @MyMy-tv7fd 2 months ago good to hear from you and your progress 3 Wellness Messiah with Rimon Reply @ConnieB17 @ConnieB17 2 months ago Wishing your wife a full recovery. Thank goodness she had you in her corner to advocate for her when she needed it most. I'm grateful that we have the nhs, especially in an emergency, and I do believe the majority of the staff want to do their best for people. But the system is flawed. I've noticed that when using a free service, what you're offered is often what's within budget or convenient, rather than being told of the best treatment options. It's impossible to make an informed decision when they only give you half the facts, especially when time is of the essence. I've got my own laundry list of horror stories of family members who weren't listened to by the nhs, and who ended up with worsened conditions due to delays in treatment. Keep pushing for what you think is right and don't take no for an answer. 2 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 4 replies @jamesjones7138 @jamesjones7138 7 days ago I had an Ischemic stroke at aged 38, effecting my left arm at the onset and effecting the dexterity of my left hand in the long run. Anyway, a few years later I heard of a supplement, referred to as an 'Adaptogen' by Russian researchers, namely Schisandra chinensis. I didn't try it to help manage the symptoms of the Stroke, but found within half an hour of administration of Sc, I experienced an improvement, or recovery to be more precise, in the dexterity and control of my left hand, by as much as 25% I think and this still happens today when I take it. Also as well as Sc, I have found the following supplements useful-CDP Choline ('Citicoline') and N-Phenylacetyl-L-prolylglycine ethyl ester (Noopept). Reply @georgechristoforou991 @georgechristoforou991 2 months ago May God be with your wife. 4 Wellness Messiah with Rimon Reply @homeontherange733 @homeontherange733 2 months ago The arrogance. There is a proverb, "by professing themselves wise, they became fools". Prudence would suggest that in order to rule out possible causes, they would cover all the basics as fast as they can. Godspeed to you and your wife. 8 Wellness Messiah with Rimon Reply @dageide6008 @dageide6008 2 weeks ago You are good, really good Rimon. I wis You and your wife allthe best in the future. You have a clear and informatiwe way to present stoff, and pick the good sources. I will be a member and looking forward to that and your knowledge. Reply @GS-rw9og @GS-rw9og 1 month ago waiting anxiously for your peptide research results,, Praying much, daily for u and precious wife 1 Reply @lindaallen2412 @lindaallen2412 2 months ago A very speedy and full recovery to your wife well done you for standing strong and fighting for your wife, good news to yet again show how great NMN is 2 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @joannsmith9 @joannsmith9 2 months ago I’d like to know more about peptides. I wish you and your wife the best you have one of the BEST scientific minds out there, so if there an answer im sure you won’t stop till you find it. 3 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 3 replies @kateclark8051 @kateclark8051 2 months ago Thank you so much for sharing this 3 Wellness Messiah with Rimon Reply @GS-rw9og @GS-rw9og 1 month ago JESUS bless u and your precious wife 1 Reply @jriurato @jriurato 1 month ago Best Wishes. Thank you for sharing 2 Wellness Messiah with Rimon Reply @mbmurphy777 @mbmurphy777 1 month ago (edited) Yeah, that is absolutely shit care. In the United States stroke possibility is an emergency and quality is measured in time to getting TPA or interventional angiography. Every one with any ounce of medical knowledge knows that a CT scan will not illuminate ischemic stroke. It will only show a hemorrhagicum stroke. Therefore, the proper course is to get an immediate MRI if the CT is negative. I don’t know what malpractice laws are like in England, however, they care that you got at the first hospital and first set of doctors was absolutely clear-cut malpractice. 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @shus5787 @shus5787 1 month ago All the best 2 Wellness Messiah with Rimon Reply @danladking9788 @danladking9788 5 days ago Did they ascertain what causes your wife's stroke? Reply @petroschristodoullou3222 @petroschristodoullou3222 1 month ago best wishes Reply @manjulacox2776 @manjulacox2776 2 months ago ❤ 2 Wellness Messiah with Rimon Reply @christopherellis2663 @christopherellis2663 2 months ago Doctor Knowall 👇 1 Wellness Messiah with Rimon Reply @augurcybernaut4785 @augurcybernaut4785 10 days ago Why would this guy talk about “other procedure” without naming the procedure…. ? How is that helpful? Reply @erdnadre7566 @erdnadre7566 7 days ago is you wife vaxxed? Reply 1 reply EXERCISE, Resveratrol & Antioxidants: Avoid this MISTAKE! (ep. 3) Wellness Messiah with Rimon 36.4K subscribers Join Subscribe 1.2K Share 36,466 views Mar 25, 2023 Resveratrol. The mysterious molecule, popularized by doctor David Sinclair. A controversial supplement that works differently in your body with different doses. And now, shockingly, works differently in different circumstances, and in different times. If you exercise regularly, did you know resveratrol can take away from you the benefits of your exercise? It happened to many in our longevity community. How could a supplement keep your body young all the while sabotaging your exercise? You’ll understand why most people take resveratrol at the wrong time. And what to do about it? We’ll discover another shocking study showing resveratrol increases oxidation levels. That’s quite a mystery which we’ll investigate. We’ll use David Sinclair's discoveries. And, to expose how this mysterious molecule works, we’ll travel the journey into antioxidants and their impact on your longevity. Vitamin C, Vitamin E, and much more. Should you take them? More today: What’s the best time to take resveratrol during the day: Should you take it in the morning, like Dr David Sinclair, or in the evening? What’s the WORST time to take resveratrol? Should you take resveratrol every day? Be ready for some serious myth-busting. By the end of this investigation, you’ll have life-changing insights into how our DNA works, what exercise does to your DNA, where resveratrol fits here, and the perfect timing of resveratrol… for a lifelong habit of longevity and health, as easy as popping a pill. ---------------------------------------------------------------------------------------- ✅ Check the special deal of habits creation app + my routine for longevity: https://wellnessmessiah.com/app Disclaimer: I'm an affiliate of the company - I trust their product. Buying will support my channel. ---------------------------------------------------------------------------------------- ✅NEXT: Episode 4: • RESVERATROL POWER... PREVIOUS: ✅ Episode 1: • RESVERATROL & Dav... ✅ Episode 2: • RESVERATROL & Dav... ---------------------------------------------------------------------------------------- ✅ Become a channel member on Patreon. Join with $1 & get access to the 10 resveratrol habits & earn an honorary mention in future videos. ✅ Upper levels receive my entire supplement routine & brands (worth $100). https://www.patreon.com/WellnessMessiah ---------------------------------------------------------------------------------------- References: https://physoc.onlinelibrary.wiley.co... https://physoc.onlinelibrary.wiley.co... https://www.sciencedirect.com/science... https://jamanetwork.com/journals/jama... https://www.ucl.ac.uk/~ucbtdag/Wenner... https://pubmed.ncbi.nlm.nih.gov/15879... https://www.ncbi.nlm.nih.gov/pmc/arti... ---------------------------------------------------------------------------------------- ✅ The favourite videos on this channel - playlist: • Longevity Favorites ---------------------------------------------------------------------------------------- The Wellness Messiah podcast is available on Spotify, Apple Podcasts, and Overcast. ---------------------------------------------------------------------------------------- Credits: Scott Buckley Disclaimer & Disclosure: The information in this video and/or at this channel is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. It is intended as a sharing of knowledge, educational and information from the research and experience of Rimon, who encourages you to make your own health care decisions based upon your research and in partnership with a qualified health care professional. Rimon is not a medical doctor. If there is a contradiction between the advice here to your doctor or local authorities, always go with the doctor and the authorities. Statements made, or solutions suggested in this video and/or at this channel are not intended to diagnose, treat, cure, or prevent any disease. Key moments View all Wellness Messiah with Rimon 36.4K subscribers Videos About 272 Comments rongmaw lin Add a comment... @WellnessMessiah Pinned by Wellness Messiah with Rimon @WellnessMessiah 3 months ago ✅ Check the special deal of habits creation app + my routine for longevity: https://wellnessmessiah.com/app Disclaimer: I'm an affiliate of the company - I trust their product. Buying will support my channel 17 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 9 replies @pestimom6572 @pestimom6572 3 months ago This is one of the best videos I've seen. You cover the science and the practical take aways. This is very helpful for understanding resveratrol and the mechanism of other antioxidants as well. Great job! 17 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @shrimboi8909 @shrimboi8909 1 day ago 6/29/23... I had my mum taking NMN three months ago with Resvesatrol. Today, she was so excited to report that she haven't felt this good in a long time. BTW, she's 82 years old. She normally wakes up feeling tire and groggy after coffee and small breakfast. But today she felt fully awake and full of energy. She walked 1 mile to the local swimming pool and didn't feel tire at all. Walked back home and did some outdoor exercise. Some sunning and still felt good after all that. She said she felt like a younger version of herself. I was pleasantly surprised and happy. I couldn' believe what I was hearing! Was it the NMN and Res? Don' know for sure but I want to believe it. BTW, she takes NMN and Resversatrol around 9pm every nite before bed. I do the same. I noticed that taken before bed seem to work best. We started buying NMN from Probase Nutrition. It was good pure NMN. Now I switched to Do Not Age. I noticed that Do Not Age's NMN is more powdery in texture than Probase. Both have similar taste. Reply @emilguste @emilguste 3 months ago This is amazing stuff, Rimon. I hope you also start a series on NMN like this. 22 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @OlafCoenen @OlafCoenen 3 months ago Excellent video. My wife (47) and I (51) have been taking Resveracel from Thorne daily in the morning. Overall fairly low dose of Resveratrol. We are very lean, do sports daily and I do intermitten fasting (16/8). Based on this we will wind down the daily use of Resveracal/Resveratrol. So likely take it from time to time on less healthy days (the cruise example you gave) and then in the evening only. We will keep it in mind for our older age to potentially increase then again, as for now our daily sports (cardio/strength alternation) is probably enough stress on our body/cells. So thanks for the video: makes our health routines hopefully even better AND it saves us money as well. 😊 9 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @47allaussie @47allaussie 2 months ago Makes sense to me thank you Rimon. I've been taking it the wrong way - in the morning during interment fasting and then doing intense exercise early afternoon. Will change that after your explanation. 2 Wellness Messiah with Rimon Reply @es1653 @es1653 2 weeks ago Thank you for this health information for everyone. In the past research was hidden, only available to very few. I have only taken three resveratrol capsules, a few days apart, each 400 mg. But I will start taking 100 mg. or 200 mg. Instead. I have gone through many different vitamins to find the correct combinations. Thank you and a gigantic thanks to Dr. Sinclair for permitting this knowledge to escape the hallowed halls of learning! Reply @louismason5677 @louismason5677 13 days ago Wow, one of the best and most informative videos after being in the medical community for many years. 1 Reply @sukeshjph @sukeshjph 3 weeks ago I alternated between 100mg of Pterstilbine and 50 mg of Reserveratol. I also do strength training and running. After watching this video i think it's best to take 50 mg of Reserveratol or Pterostilbine every other day or 3-4 times a week.I'll switch taking them post exercise(Not immediate) as well. Low dose anti-oxidants are good but don't ever want the good effects of exercise to be gone. Reply @e4lvsops @e4lvsops 3 months ago What I wonder is, how long after exercise or fasting would it be good to take Resveratrol so as to not negate the positives of what we just did. Another way of thinking about it is: how long do the benefits of exercise that are affected by Resveratrol last? 1 Reply @ConnieB17 @ConnieB17 3 months ago (edited) Thank goodness I watched this today! I have NAC and CoQ10 in my amazon basket as we speak! They're recommended for older women trying to improve egg health. I'm a bit torn with CoQ10 because the studies showed an improvement in egg health by taking 600mg daily of Ubiquinone/300mg Ubiquinol ideally 90 days prior to conception. I think the positive results in ovulation were after taking it for about six weeks but I'm not sure if they checked the long term impact. I'm swapping the antioxidants for sirt 6 activation instead with fucoidan/algae and some 72 hr fasts to boost stem cell health. Not forgetting NMN protocols, obviously! 😇 But vitamin E is added to my evening primrose oil as a preservative, and A+E are in my multivits 🤦 Oddly enough I was thinking of swapping the vits for spirulina and folic acid. Btw in case it's of help to your wife, I recently heard glycine has preventative properties to minimise stroke risk, but you probably already know this. Ok so based on everything you've said so far I think I'm on track. I can see how your app could be helpful to keep people on track with their habits as the longevity lifestyle takes work and planning. But it's progress not perfection! This channel is such a help to me. Thanks for another informative video. 9 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 7 replies @hongyin90 @hongyin90 1 month ago Many thanks, Rimini. How about fisetin? Since resveratrol and fisetin are similar in structure, should we assume the lesson you presented applies to fisetin? Reply @CamiloVergaVideos @CamiloVergaVideos 3 months ago Excellent video, as always, Rimon. Very complete and practical. Congratulations on your work and thanks for sharing!!! 2 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @henrymroth9455 @henrymroth9455 3 months ago Wonderful information! You make complicated, controversial information much easier to understand. Well done! You have quickly become my first choice in learning about anti-aging. H 4 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @joeblow2183 @joeblow2183 3 months ago (edited) Awesome report Rimon thank you! Now I’m going to only take a large dose when I eat out. No more in the morning and I also train everyday unless I get overtrained. I’m 67 and don’t miss many workouts. I wonder is there anytime I should take a super low dose to help spark the daily dose of nmn like Sinclair? Although he’s taking a large dose… but he doesn’t workout very much. I’m definitely to cut back on resveratrol and I’m going to stay tuned to your next report. Lately I’ve been putting a dose of ginseng in my mouth along with nmn. 9 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 3 replies @CamiloVergaVideos @CamiloVergaVideos 1 month ago Thank you very much Rimon! I wanted to ask you a question, you who know so much and have investigated the matter, to see if you can help me think of something. There is a 2019 study that showed that resveratrol is capable of converting senescent cells in young cells that reproduce again. I mean, in a way, it's the opposite of a senolytic. The problem is that I was taking quercetin and resveratrol together. Now, after watching your videos and thinking a bit, I take quercetin (250 mg phytosome) one day, to induce apoptosis in senescent cells, and another day resveratrol to improve those that quercetin couldn't kill (say, every other day). Theoretically it should work, what do you think? (I'm 40 years old. I also take nmn, spermidine, d-ribose, and metformin, except on weekends that I do a stationary bike and a little weights). Reply @giovannidominoni @giovannidominoni 1 month ago I wanted to take a Quercetin/Bromelain supplement to reduce the symptoms of hay fever, but I was wondering if Quercetin in high doses will have the same effect of Resveratrol in high doses (and, as you are saying, resveratrol should be taken at a low dosage) Reply @daimos777 @daimos777 3 months ago (edited) I trust Prof. Sinclair, he is a geneticist and sees how resveratrol works in details. There is a reason why he uses such and not other doses. I take 250 mg to 500 mg a day, 4-5 days on and then 2-3 days off - usually weekends. 6 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @bilbyguy2389 @bilbyguy2389 3 months ago Great video and information. I am a 62 yrs old male. I am taking each of the following 3 days per month: Sulforaphane, Fisetin, Grape seed extract and Quercetin. That equates to a different antioxidant for approx 3 days per week. I am wondering if all antioxidants that are taken externally have the same negative impact as resveratrol can have. I am 'hoping' that the cycling and varied antioxidants will lessen the negatives and allow for positive impacts. Or else may be I should ditch all antioxidants and focus on Sirt6 Activation. I exercise well 3/4 times per week. Any comments welcome. 2 Wellness Messiah with Rimon Reply @lungarotta @lungarotta 3 weeks ago Thank you for your precious information. This is just what I needed to know. But I have another question? What about pterostilbene? Can it substitute resveratrol and have the same bene fits? Reply @henryoz @henryoz 3 months ago Very informative and helpful information. Thanks Rimon! Could you please do a video of taking TMG? Is it all necessary? How much should I take and what problems will I have if I do not take it? Thanks 2 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @antoniozisa @antoniozisa 3 months ago This is brilliant. So many doubts are solved now. Maybe just a follow up question. Sinclair also takes quercitin and fisetin. Should we time them as resveratrol? Thanks so much for your help Rimon 2 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @aussiert @aussiert 2 months ago What are your thoughts on Dr Brad Stansfield’s analysis on resveratrol where he says basically to stop taking it as it causes more harm than good? Thanks for your time. 1 Reply @emil8367 @emil8367 3 months ago Thanks for the analysis. Still, even it seems correct, it's easy to overlook something in such large amount of information and that's why a direct confrontation with someone (like Sinclair, Matt Kaeberlein, Vera Gorbunova, Jin-Xiong She, Charles Brenner, etc) would be beneficial, to see if all the information which you provide are correct. ps. Sinclair said recently on a conference in India (YT video: fsUUgTPtwnc) that he takes now 0.5 gram of NMN only. Curious why ... 3 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 3 replies @camjfisher @camjfisher 3 months ago I would like to question the logic of taking resveratrol after the workout. As opposed to 24 hours before. Following exercise, our bodies go through a repair (and strengthening) process, particularly during rest at night. As the studies suggest wouldn’t taking resveratrol blunt this process/benefits if taken afterwards? Might it not be better to take 24 hours before so most is out of the system by the time we exercise. Would be interested in your thoughts? Great work with the channel. Reply Wellness Messiah with Rimon · 1 reply @sooooooooDark @sooooooooDark 3 months ago wouldnt it make sense to take (very) high dose resveratrol for its high dose senoyltic effect during waterfasting? (the "very" because of the absorption issue, to make up for the lack of fat/alcohol carrier) Reply @steadiguy @steadiguy 1 month ago I'm intrigued with your deep dive into Resveratrol. It's been talked about and suggested for ingestion and health benefits, for I think, 30 some years that I've noticed. However, I'm confused by how little is known about you. A casual Google search comes up with 2 pages and no mention of who you are. Perhaps you are the Messiah. You've come back, taken a look and settled in on a new role as a Wellness Messiah. I mean it can be argued that things, the creation of Christianity aside, didn't go all that well personally for your physical well being. And who wants to go through that or something similar all over again? Still, questions remain. Reply @johnjclawson @johnjclawson 3 months ago So does Sinclair cycle his Resveratrol intake or not ? Also isn't he always taking a high dose ? (If these are true statements) I'd love to understand Sinclair's reasoning on his routine 11 Reply Wellness Messiah with Rimon · 6 replies @BryanDalleStelleOfficial @BryanDalleStelleOfficial 2 months ago If you were to take both resveretrol and Nac, would it make sense to use one or the other on alternate days? (Ex. Monday resv, Tuesday Nac etc) Reply @keithmarshalldds511 @keithmarshalldds511 3 months ago I enjoyed and learned much here. I would like some clarification on the form of Vitamin E; was it the alpha tocopherol form or the alpha tocotrienol form? No surprise if it’s the former which has been shown to hinder the benefits of the latter. Reply Wellness Messiah with Rimon · 1 reply @DragonRyderNyx @DragonRyderNyx 3 months ago Thank you! 🥰. In Dr. Sinclair's recent interview he mentioned he now takes 500mg of NMN.. I was curious as to your thoughts. Reply Wellness Messiah with Rimon · 3 replies @biggie9817 @biggie9817 3 months ago Taking Resveratrol "after" exercise. is not a specific enough guideline. To me a time interval is necessary, as you don't want to introduce the anti-oxidant too soon after exercise for the same reasons you shouldn't be taking it before exercise. So a more definitive timing is necessary. 3 Reply @aaronsttod4215 @aaronsttod4215 3 months ago Thanks Rimon, could i propose you to investigate Quercetin as you did with Resveratrol? Thanks 7 Reply Wellness Messiah with Rimon · 1 reply @altaj2688 @altaj2688 3 months ago Can somebody make short summary of the results? 38 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 3 replies @mag4926 @mag4926 3 weeks ago What usually happens when people go on vacation and stay in hotels is this: they look for excuses for sloppy planning and lack of discipline! It's ridiculous and absurd to blame vacation for poor diet. Wheni go on vacation, i plan everything in detail beforehand so that i can keep my diet consistent. everything else is a flimsy excuse and ridiculous at that! 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @j4s0nm1cha3l @j4s0nm1cha3l 2 days ago If the minimum time after taking resveratrol is 9,2 hours to exercise, what about the other way around? What is the minimum time after exercise, until we could take resveratrol? I usually take resveratrol with meal, about 6 hours after exercise. Is it ok? Reply @ferdomrkvicka1247 @ferdomrkvicka1247 3 months ago Looking forward for other videos ,keep up good work !!! Reply @wallexx-rl9nj @wallexx-rl9nj 2 months ago Thank you Rimon. If one searches the Vitamin C topic it gets more confusing: “Placebo-controlled research, some of it double-blind, has shown that taking 400 to 3,000 mg of vitamin C per day for several days before and after intense exercise may reduce pain and speed up muscle strength recovery.” It’s on human and not mice and could easily interpreted as overall +ev for the human. 1 Reply Wellness Messiah with Rimon · 1 reply @papyber @papyber 3 months ago BRAVO, well done. This helps us act intelligently. Thanks. 3 Wellness Messiah with Rimon Reply @ohfft @ohfft 4 weeks ago Resveratrol could temporarily reduce exercise endurance by dropping blood sugar levels. 1 Reply @lungarotta @lungarotta 3 weeks ago Another important question: resveratrol blunts the benefits of intense exercise. What about a person who does not exercise intensely? The logic tells me that negative side effect should not occur, right? 1 Reply @candrad @candrad 3 months ago Thank you so much,this explains a lot! 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @crnavjeverica7657 @crnavjeverica7657 2 months ago My family (4 members) started taking nmn, resveratrol, little bit of olive oil and black pepper mixed together. We all took same doses (500mg nmn and 150mg trans res.). Two of us had headaches, one of those two had fever also and starting to get blue color nails and seems like blood from that person is thinner and lighter. What could be possible answer to this? Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 3 replies @bernhardwalther @bernhardwalther 3 months ago Thaaanks so much. I thought you already made you best video but not. It was dense and very interesting. It fits with other studies made with crisp on res. I just wonder how long to wait after workout to take resveratrol? If you eat quite soon after, maybe resveratrol will stead mess with the effect of exercise? Anyway I didn’t connect the dots with the ‘unhealthy’ meals. Thanks again for the clarification. At the end music covers a bit your voice but removes nothing to the very interesting sum up. Stay healthy, stay young 😊 2 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @edwinsiegert @edwinsiegert 3 months ago Excelent!!! I apreciate your recomendations. Good analisis and logic. 3 Wellness Messiah with Rimon Reply @rondesilva3077 @rondesilva3077 7 days ago (edited) I started this video not very interested and ended up watching the whole video (almost one hour)... excellent science and common sense based protocols Reply @nomi6798 @nomi6798 3 months ago Wow that was very well explained, thanks 1 Wellness Messiah with Rimon Reply @TPMaverick2022 @TPMaverick2022 3 months ago Very informative. Thank you! 2 Wellness Messiah with Rimon Reply @grampalerxst5962 @grampalerxst5962 3 months ago You mention "low dose" and "high dose" frequently, but I didn't see where you quantified low and high (apologies if I missed it). Any guidance on what constitutes low dose versus high dose? 1 Reply Wellness Messiah with Rimon · 1 reply @patite3103 @patite3103 3 months ago Great video! could you do a video showing good places to buy resveratrol and which quantity per kg/body. Thank you Reply Wellness Messiah with Rimon · 1 reply @KirstiCheetahh @KirstiCheetahh 3 months ago Great explanation. One question: Why don't you take Pterostilbene instead of Resveratrol? 2 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 9 replies @georgezibilich4975 @georgezibilich4975 1 month ago Rimon, what dose of Resveratrol do you take as a low dose? Reply @SPX3455 @SPX3455 3 months ago (edited) If you are taking a very low dose of Reseveratrol like 50 mg. every other day, it should not make a significant difference when you are taking it. High dose 500 mg and above may benefit from keeping it away from exercise. Reply Wellness Messiah with Rimon · 1 reply @theluckyman74 @theluckyman74 3 months ago Red light therapy also increases oxidation levels. But is still effective. Wellness Messiah with Rimon Reply @jouan1 @jouan1 3 months ago I am 73 years old and in good health. I just started taking a low-dose resveratrol per your recommendation late in this video you talked about taking high-dose Rosevere a troll when you are over 50 to 60 years old so now I’m a bit confused as to the dosage. 3 Reply Wellness Messiah with Rimon · 4 replies @ShaneOn54 @ShaneOn54 2 months ago I’m not sure when to take it now. I do high intensity training everyday ( gym 4 times a week and 10km runs on the off days) 2 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @ricardocalegari2923 @ricardocalegari2923 1 month ago Is this only valid to resveratrol supplement or also to foods that are source of this antioxidant? I mean, should I also not eat blueberries in the day that I do an intense workout? Reply @33Crazydude @33Crazydude 3 months ago I'm learning much for sure, thank you👍👍 2 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @artten5002 @artten5002 3 months ago You are a longevity detective! 2 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @melkor321 @melkor321 11 days ago Very nice work, this was an awesome video Reply @lollyb8808 3 months ago I normally take ginger and curcumin before exercise, does this mean I should take it after? I take them for the anti-inflammatory properties for a autoimmune disease. 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @leannebolden0706 @leannebolden0706 1 month ago Will resveratrol help lower a high platelet count from blood cnacer if taken daily? Reply @NikoxNobu @NikoxNobu 1 month ago Could it be that sinclair takes a high dose of resveratrol to counteract the potential cancer risk of the nmn? 🤔 Reply @pjaworek6793 @pjaworek6793 1 month ago This show is epic! Reply @ginamurdza9704 @ginamurdza9704 9 days ago How much is low resveratrol dosages? How much is considered high resveratrol dosage? Reply @firstpagetiktok7685 @firstpagetiktok7685 3 months ago I think ginsenosides might be better to take with NMN Reply @123axel123 @123axel123 2 months ago Great but what dosage is high and low? How much to take each time? How can you miss this? 1 Reply @videosammlung4859 @videosammlung4859 1 month ago great infos, great explanation Reply @levikohen924 @levikohen924 2 months ago What about how to naturally fix Ulcerative colitis? 1 Reply @marcusadell6985 @marcusadell6985 2 months ago Great video to watch once you have a little bit deeper knowledge about resveratrol (and NMN). Though the music over some parts of the info, is really annoying and makes it a lot harder to hear what you're saying. Like at 47:30 and a few parts before that. Reply Wellness Messiah with Rimon · 1 reply @Hazzatronic @Hazzatronic 2 months ago So what dose and how many times a week and what time should a normal person be taking this? Reply @chch6171 @chch6171 1 month ago Must we take resveratrol right after a large meal ? Or like few hours later is fine? Reply @perfectworldofentanglement152 @perfectworldofentanglement152 2 weeks ago (edited) So I can asume GlyNAC or NAC has same effect on training? I currently take Glycine and NAC to detox my Liver, was fuming Benzen for like 10 days, even from my eyes, like chopping onions 24/7 lol. Taking NMN and Resveratrol to repair kidneys now. Reply @BryanDalleStelleOfficial @BryanDalleStelleOfficial 2 months ago Do you suggest taking it in pills or powder? Reply @frankiesierra7218 @frankiesierra7218 3 months ago The timing should be related to ampk and mtor pathways and circadian cicle Reply @bolunixan @bolunixan 2 months ago What's the difference between trans and normal resveratrol? Reply @TPMaverick2022 @TPMaverick2022 3 months ago (edited) BTW, what would be the recommended low dose for a healthy active person? Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @catherinekchen @catherinekchen 2 months ago Hi I subscribed UltiSelf via your link. But to be honest it really feels like a scam, the among of products it keep pushing me to buy more. The $37 not even clear is for how long. I get it because of you seems very detail and trying to get a copy of what you take. Two things, could you do a video on how you use the UltiSelf to help you? Second, after reading your list, it’s a lot for me to absorb since I am not in a habit of taking supplements also disappointed there is not NMN. I am female in mid 40s and would like to try NMN, is there a brand and dosage you would recommend? Thank you! 2 Reply 1 reply @soylentmajority989 @soylentmajority989 3 months ago If Resveratrol works, why hasn't Sinclair had it banned? 1 Reply @kianleyon6613 @kianleyon6613 3 months ago Great video, do you have a video on what is a low level vs high level of resveratrol. 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @jgs9911 @jgs9911 3 months ago Rimon, thank you again! 1 Reply @lorenzotrombetta6887 @lorenzotrombetta6887 2 months ago Mercury and microplastic in fish, glyphosate in granes, heavy metals in tea, cacao, almonds, seaweed. How much do they impact longevity? Reply @Gismotronics @Gismotronics 3 months ago (edited) I have an idea... We have to 'buy you a coffee' to have content without those annoying stock video/image inserts. 🙂 Great content apart from that so definitely worth some tips. Thank you. Reply Wellness Messiah with Rimon · 3 replies @mildredbauza9940 @mildredbauza9940 2 weeks ago Does alpha lapoic acid one of the anti-oxidants that increase mortality? Reply @gloriagolemboski4515 @gloriagolemboski4515 2 weeks ago I’m 83 and take 100 each day and a Quercetin at night . Is this two much. Please reply. I take many other vitamins like d3, k2/m7, zinc, magnesium.potassium etc. Reply @georgechristoforou991 @georgechristoforou991 3 months ago So, we need to make a form of resveratrol that is not an antioxidant. Reply @sooooooooDark @sooooooooDark 3 months ago vitamin c activates lots of enzymes in the body its not just an antioxidant enzymatic activation is just about the most important thing for quality of life and quantity of life Reply Wellness Messiah with Rimon · 1 reply @libertysong1 @libertysong1 2 months ago (edited) If the French Paradox led researchers to resveratrol then why not have a little fun & drink a glass of red wine with the meal? It's really quite simple wouldn't you say...red wine with meal ie low dose resv= better longer health....am I missing something here? 2 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @pkstiever @pkstiever 3 months ago So what about those over 70? We know their antioxidant system isn't great. So low dose Resveratrol every day or still cycle? 2 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @geode232 @geode232 3 months ago How long after intense exercise will the body be creating antioxidants and other benifits itself? Perhaps better to wait till next morning after exercise day for low dose Resveritrol?? 1 Reply Wellness Messiah with Rimon · 2 replies @dreamchaser7554 @dreamchaser7554 1 month ago tks . very detail and scientific thinking. Reply @thepatternforms859 @thepatternforms859 3 months ago Why take resveritrol when you can just take NAC+Glycine OR just take Glutathione? 3 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 3 replies @peteostro @peteostro 2 months ago Sinclair takes a gram of resveratrol every day! Why is this? He does not cycle. Reply @chch6171 @chch6171 2 months ago So now we shouldn’t take anti oxidant vitamins such as beta carotene, vitamins A and E? 😩 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @ronlev1894 @ronlev1894 1 month ago I wish you had a short, concise conclusion of all your valuations, early on in the lecture. Otherwise, you have to listen to almost an hour to get the real information you want in the first place. Just a thought. 1 Reply 1 reply @johnbielenda7336 @johnbielenda7336 3 months ago (edited) the higher dose and anti cancer does it for me..........i did not know my mother cause of that stinkin disease (passed when i was three). Reply @ironminh @ironminh 3 months ago Rimon what is considered a low dose of resveratrol? 6 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 4 replies @sooooooooDark @sooooooooDark 3 months ago 5km walk once a week isnt intense its...not even moderate... it may be intense for bmi >45 and moderate for bmi >35 or something xD Reply @PayamDataRecovery @PayamDataRecovery 3 months ago Too long? Watch from 42:00 for the good stuff. 1 Wellness Messiah with Rimon Reply @srikumarc @srikumarc 3 months ago Hi Simon, what is considered low dose in terms of mg. 2 Reply Wellness Messiah with Rimon · 3 replies @heman691 @heman691 3 months ago I thought the latest is higher dose kills cancer cells rather than longevity it’s getting confusing Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @GHFrankie @GHFrankie 2 months ago So we don't necessarily need to take NMN and Res together? 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 3 replies @suelakolpepa2305 @suelakolpepa2305 2 months ago Where can we find the right resveratrol and NMN? Reply 2 replies @supercal333 @supercal333 2 months ago How long after doing exercise before one can take Resveretrol or antioxidants? Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @carloscarion1748 @carloscarion1748 3 weeks ago What about tocotrienol? Reply @roberttohill627 @roberttohill627 3 months ago Hi Rimon, what would be the recommended dose for me, I am 65? Reply Wellness Messiah with Rimon · 1 reply @elliottrubenstein1746 @elliottrubenstein1746 3 months ago Thanks Rimon. 2 Reply @gloriagolemboski4515 @gloriagolemboski4515 8 days ago I wish someone would answer. I am taking 100gr. Of it daily with yogurt . Is that to low. Reply @cleverclogsbecky @cleverclogsbecky 3 months ago I am confused? You say take Resveratrol after exercise before a large meal!!! But you are not saying how long to wait after the exercise. Can you please answer this question. Thank you. 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @terrihoward6224 @terrihoward6224 1 month ago I don't have a clue which brand is effective and affordable. I have ms and take lions mane. Id love to start this but HOW? Ughhh Reply @MixtrisUFOimages @MixtrisUFOimages 2 months ago I would not take reveratrol 24 hoours before and after exercise Reply @candrad @candrad 3 months ago Will someone answer my question of should I take resveretrol with my nmn or not? 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @ac-js8fb @ac-js8fb 3 months ago what if i exercise everyday? when can i take resveratrol then? Reply Wellness Messiah with Rimon · 1 reply @irmantasvaitkauskas6769 @irmantasvaitkauskas6769 2 months ago what if i train 4 days a week, will it be enough to take resveratrol 3 days a week Reply 1 reply @prasadb8917 @prasadb8917 2 months ago 43:50 - when to take it? Reply @damianbachul3599 @damianbachul3599 2 months ago what is low and what is high. SPECIFICS please Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @wwm @wwm 3 months ago Not sure what is the dose of reservatrol I should take..? 2 Reply Wellness Messiah with Rimon · 2 replies @pitekxpan5845 @pitekxpan5845 3 months ago Rimon, is takin Res right after excercise will no stop body adaptation ?? Body adapt Up to few days after exercise . 2 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @eastonvannamomma @eastonvannamomma 2 months ago What about taking athletic greens? 1 Reply Wellness Messiah with Rimon · 1 reply @chaos_commander @chaos_commander 3 months ago Skip to @37:25 for the TL;DW 3 Reply @hjvela1907 @hjvela1907 3 months ago You should publish your real age. How old are you? Reply Wellness Messiah with Rimon · 1 reply @gustavopanesso7297 @gustavopanesso7297 3 months ago Can we make this summary shorter please. Get to the point. Reply Wellness Messiah with Rimon · 1 reply @dlbdlb3919 @dlbdlb3919 1 month ago You need to redo this video, it felt like none stop yaking 1 Reply @sozikurd7400 @sozikurd7400 1 month ago ❤❤❤❤❤❤❤❤ Reply @christopherellis2663 @christopherellis2663 3 months ago Presently not opening the next load for a couple of months. 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @leonardosepulveda8385 @leonardosepulveda8385 3 months ago It is disappointing to see Rimon increase the size of the video intentionally making at the end completely confusing content by circular argumentation. So good content over monetized. Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @antho22wateva @antho22wateva 5 days ago We gunna eat the cake and hev it too guyz Reply @gloriagolemboski4515 @gloriagolemboski4515 8 days ago How aboutansweringGloria Goemboski. It’s important tohrt. Reply @mjlobban1971 @mjlobban1971 3 months ago For goodness sake, why not give time logs so we can do to the parts we want to know, rather than slogging through the whole 45 mins!!! 2 Reply @copleysq @copleysq 3 days ago You talk too fast and unclearly. Reply @zvishapiro6080 @zvishapiro6080 3 months ago Too long and too complicated. Need executive summary and begining Reply Wellness Messiah with Rimon · 1 reply @user-ut7fd1oy4b @user-ut7fd1oy4b 3 months ago L😅ĺl 3:37 2 Reply @levondarratt787 @levondarratt787 3 months ago Man Ur videos are too long. You're not a scientist, that is explaining research results in A paper.... You need to find a way to clearly communicate information.... 5 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 4 replies RESVERATROL MYSTERY: Why Taking Too Much HURTS Your Longevity (ep. 2) Wellness Messiah with Rimon 36.4K subscribers Join Subscribe 1.2K Share 36K views 3 months ago If you take resveratrol… did you know resveratrol works differently in your body depending on how much you take every day? If you’re not careful about how you take resveratrol, you may achieve completely different benefits from the one … 218 Comments rongmaw lin Add a comment... @WellnessMessiah Pinned by Wellness Messiah with Rimon @WellnessMessiah 3 months ago (edited) ✅ Check the special deal of habits creation app + my routine for longevity: https://wellnessmessiah.com/app Disclaimer: I'm an affiliate of the company - I trust their product. Buying will support my channel Watch episode 3: https://youtu.be/HC61Gg5lPD4 P.s. Ironically, after 8 years I've just replaced my old laptop. This video was an honorable retirement party to an old 2015 friend. It's still alive though, supporting the longevity theory :) 9 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 4 replies @stephaniejohnson1450 @stephaniejohnson1450 1 day ago I absolutely love the way you break down and compare different data and opinions. Watched several of your videos and this has helped me sort through why there's conflicting studies and information. Can you do something like this for NMN? Reply @Grythpyke @Grythpyke 3 months ago I'm so grateful that Rimon takes the time to dig down into the research that would be beyond my ability and time. So well presented and balanced 18 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @larsnystrom6698 @larsnystrom6698 3 months ago I think it's very simple: Reservatrol is a stressor! A little stress activates the cells response a little more than necessary. And this is the beneficial effect. But too much stress is harmful. Many poisons have this effect. So does other stressors, like heat and cold. Vegetables contains many poisons. But we know which vegetables stresses us just enough. In a way, exercise is also a stressor... 35 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @irenegardiner6857 @irenegardiner6857 3 months ago Thanks for putting this together Rimon. You put a lot of work into it. 13 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @davidtempest7175 @davidtempest7175 3 months ago Move over Dr. Brad......this channel is now number one for unbiased detailed analysis. 39 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 3 replies @mikegatesyoutubb @mikegatesyoutubb 3 months ago This video provides an INCREDIBLY helpful and cogent explanation of data on resveratrol’s effects and the mechanisms behind it, relying on numerous recent studies on the topic. Best out there; awesome! 11 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @felicisimomalinao1981 @felicisimomalinao1981 3 months ago Much thanks Rimon for the meticulous research. Looking forward to epi 3. 9 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @henvest3491 @henvest3491 3 months ago I take fiestin 2 days per week , quercetin, resveatrol and pterostilbene 3 days per week. I had a full blood test. I was very happy with my results especially cholesterol. Only out of scope markers were shbg and testosterone both very high but had a normal free testosterone level. Doctor couldn't explain it and was surprised at my supplements.... 5 Wellness Messiah with Rimon Reply @oolala53 @oolala53 2 months ago I am going to start asking on all of your videos that I come across to. Please share with us the protocol you used to put on so much muscle in just four weeks. I know it might not work for an older person but I’ve been eating a lot of protein over the last year and a half and I want to cut back on it. But I lost a lot of muscle over the last 10 years and I feel like I need to push to get some of it back before I Curtale my protein intake and concentrate more on maintenance. 2 Reply @lindaallen2412 @lindaallen2412 3 months ago (edited) WOW, I just feel I have been to college, my brain hurts but in a good way, thank you so much for explaining all this in a way I can understand, this has to be one of the best and most comprehensive video, this is so important it really needs to be out there, thank you 7 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @emil8367 @emil8367 3 months ago (edited) Thanks for informative video. Good to do an interview with some other specialist in this matter, to make sure about your investigation, I think it is important to confirm, to not overlook anything. Also, worth to analyse the absorption, which you didn't mention. Maybe it's important when you consider low dose 🙂 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @davidzeal8915 @davidzeal8915 3 months ago Dear Rimon, I would like to express my heartfelt appreciation for your wonderful and informative video. For over a year now, I have been taking 1g of resveratrol per day, being in my early forties and with a history of heart disease. Although I am unsure whether I have any tumors or cancer, I believe that I do not. After watching your insightful video, I find myself in a dilemma whether to alter my resveratrol dosages or not. I would appreciate any recommendations you may have on this matter. Once again, thank you for sharing your valuable insights. 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @pjaworek6793 @pjaworek6793 3 months ago Love it, thanks! I'm eyeballing 50-100mg resveratrol every other day, 500mg quercetin on the alternate days, was taking 200mg fisetin once month but after this episode, I think I'll change that to quarterly until maybe my mid fifties, I'm now 47. 6 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @ConnieB17 @ConnieB17 3 months ago I posted an earlier question and then I realised you'd actually answered it in the video. The perils of trying to absorb science stuff whilst multi tasking. Anyhow, fantastic info as always and I'm adjusting my protocols accordingly. 3 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @jgs9911 @jgs9911 3 months ago Another excellent video. Looking forward to #3. Thank you 2 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @mattcummings6131 @mattcummings6131 3 months ago When I reread David Sinclairs' book, I had the impression that mice obsorb resveratrol differently than people do. I took it as maybe they have better bioavailability than us, so a weight conversion formula between us and mice might not be accurate. 3 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @AshtasticAcrobat @AshtasticAcrobat 2 months ago This makes sense. Just like any other vitamin such as A or iron etc, at certain doses are beneficial but at higher doses become toxic. Reply @birgittadevlin4206 @birgittadevlin4206 3 months ago Thank you Rimon. Dosage is complicated by differing purities/concentrations as well as micronisation and liposomal preparations. Do the two latter really increase absorption and must be taken into account? 3 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @joannsmith9 @joannsmith9 3 months ago Rimon I thank God for your wonderful brain and ability to explain extremely complicated things in a way lay people can understand THANK YOU!!!!!!!! 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @antoniozisa @antoniozisa 3 months ago Thanks so much for this additional video, you are making our life much easier. I have a question though: if resveratrol represents also a fasting mimicking tecnique, why fasting is good both on killing cancer cells and extending lifespan while resveratrol can do either of the effects? 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @ttttia4734 @ttttia4734 3 months ago I love your videos! I'm 53 and 170lbs. I think it's time for me to try to kill some senescent cells. How much resveratrol do you think I should take. Also you mention taking something every quarter after you turn 50 - what were you meaning? Thank you for your work! 1 Reply Wellness Messiah with Rimon · 1 reply @geraldk1445 @geraldk1445 3 months ago (edited) Great episode!... Would love to hear your comments on the latest Modern Healthspan channel episode where Dr. M. Zemel talks about SIRT1 activation with regards to leucine, resveratrol (low dose 100mg) and NMN. Is it consistent with the findings of your current model? 4 Reply Wellness Messiah with Rimon · 1 reply @davidgifford8112 @davidgifford8112 3 months ago Initially it seemed that taking a senolytic daily in moderate doses didn’t make much sense to me, however many people seemed to be doing just that. I finally came to the conclusion that they know something I didn’t, but it seems from the studies you site, they don’t after all and the daily dose recommendations on most senolytic supplement labels should be ignored, which to be honest I always had. 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @Chaotic313 @Chaotic313 3 months ago Are you suggesting the studies indicate that an older adult, I'll be sixty in about a week, would be better off taking the larger dose of resveratrol? You mentioned you would reconsider your dose when you reached fifty. I have been pulsing 1 gram every other day for about six months. And thank you so much for your amazing videos!!!💗 7 Reply Wellness Messiah with Rimon · 4 replies @paulkabrna345 @paulkabrna345 3 months ago (edited) Very good analysis Rimon - thank you Where do you think this leaves us with taking Resveratrol together with NMN. Perhaps going too low may partly negate the perceived benefits of NMN. (Currently I choose to take 500mg of NMN with 256mg of Resveratrol per day being 70 years old :) ) 1 Reply Wellness Messiah with Rimon · 1 reply @nickwit21 @nickwit21 2 months ago (edited) After watching this several times, I cant help but wonder if the anti apoptopic nature of Low dose Resviristrol is actually a safety signal. Is there any data to suggest that it wouldn't increase overall cancer risk? The studies seem to suggest that you may actually encourage cancer cell growth if there is an underlying disorder 1 Reply 1 reply @robertferguson7800 @robertferguson7800 6 days ago I have been taking a teaspoon every morning Can’t say I feel any different But I am now confused on taking it at all I have been taking it for about 1 year but can’t say my health has improved I do have osteoarthritis/ rheumatoid arthritis Hurt in the joints and have had both knees and a shoulder replaced My other shoulder and hip are going on me Both give me constant pain LOVE SOME ADVICE THANKA Reply @arsononemwv @arsononemwv 10 days ago Amazing show! What is considered a low dose of res ? Reply @azadehkhajeheian9430 @azadehkhajeheian9430 3 months ago Great video , thank you Rimon. I hope your wife is doing better 💕 2 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @adrgoo @adrgoo 3 months ago So Dr Sinclair is taking correct dose for his Age, great confirmation thanks for all the time you put into this Reply @trevorburris @trevorburris 3 months ago Thank you for this. So for an existing cancer patient, in theory only not medical advice, would it make since to do high dose resveratrol to potentially kill cancer cells? 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @larsnystrom6698 @larsnystrom6698 3 months ago I wonder if daily Resveratrol supplement really is the way to go. I would like to know if intermittent higher doses, say once a week, wouldn't be better. By "higher doses", I mean 0.6 -- 1 g. Although, how can we translate once a week for humans into mouse times. Perhaps once a day for them? By low doses, I consider what we get from plants to be about the right ones. But that's just intuition... 5 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @chch6171 @chch6171 2 months ago Very interesting. I’ve watched this 3 times trying to understand it. 25:42 animals with healthy and younger body but with tumors? Wouldn’t a body with tumors be considered as unhealthy? Reply @andreastchuente1643 @andreastchuente1643 3 months ago Thanks for your expertise and dedication. God bless you. 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @christopherellis2663 @christopherellis2663 3 months ago Thank you for your work 🙏 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @anetteccarlstrom4528 @anetteccarlstrom4528 3 months ago Thank You for a great Channel! I just didnt understand the dose if we are a healthy Woman over 60. I really tried to follow your advice in video but not clear. I understand low dose, is it every day? Thank You for clarification! ✨ 5 Wellness Messiah with Rimon Reply 2 replies @danielblanco8519 @danielblanco8519 3 months ago Gracias por Toda ESTA informacion que lograste reunir y simplicar para El entendimiento de todos.😀 2 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @demkal336 @demkal336 3 months ago So, from 50 years old and on perhaps an effective strategy would be: low-dose resveratrol+ polyphenol complex (i.e., red wine consumption) daily, punctuated every few months with several weeks of supplemental high-dose resveratrol. 3 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @Mikael_from_Gothenburg_Sweden @Mikael_from_Gothenburg_Sweden 3 months ago Your Longevity Reports are THE BEST. Tnx 😁 2 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @ivanschouten9382 @ivanschouten9382 3 months ago Can you explain the synergy Leucine with Resveratro and NMN.Also can you find out how much synergy or how less you need of Resveratro and NMN when combined with Leucine (and how much Leucine to take for ideal synergy) 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 3 replies @steveclews8391 @steveclews8391 3 months ago (edited) I had thyroid cancer 18 months ago. They took half my thyroid out and I'm on thyroxine. They say the cancer has now 'gone'. But it's leaving wondering if nmn and resveratrol (that I've bought since but haven't yet started) is right for me. Should I consider myself as someone without cancer, OR should I be careful that some small cancer might exist and these supplements may aid their growth. I want to get started but I'm unsure what's best. (My Dr's don't want to advise on anything like rtrol or nmn or similar. Reply Wellness Messiah with Rimon · 3 replies @TPMaverick2022 @TPMaverick2022 3 months ago Great content. Thank you 🙏 Reply Wellness Messiah with Rimon · 1 reply @tobiaskevorkazito4072 @tobiaskevorkazito4072 3 months ago That was a tremendous presentation 🥊 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @harj5338 @harj5338 3 months ago Perhaps due to resveratrol low bio-availability, Dr Sinclairs protocol of 1 gram / day could actually be a low dose? 1 Reply @georgekozub9803 @georgekozub9803 3 months ago Let's hear more about human studies, please! 2 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @Arbarano @Arbarano 2 weeks ago Could a quartery high dose of reseveratrol during a few days help killing cancer cells? Reply @laurentiurudeanu4102 @laurentiurudeanu4102 3 months ago Interesting information, but hasn't this same topic on low/high resveratrol dose been covered in other videos in the past? Reply @lja961953 @lja961953 3 months ago Thank you for excellent videos, I have just started taking 300mg of Resveratrol + Pterostilbene, 70 years old, any thoughts, keep up the good work !!! 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @tomson11 @tomson11 3 months ago When you say high dose or low dose do you mean the overall intake over a long period of time or does the singular dose matter as well? In other words, if I take 200mg once a week do I still reap the same benefits as taking 50mg every other day? 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @lionick8 @lionick8 3 months ago Good job, but I'm still not convinced. Why such a respected scientist like Sinclair is wrong about the dosage? 1 Reply @AT-xl9db @AT-xl9db 3 months ago Your channel is so underrated! 😊👍 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @waynewells2862 @waynewells2862 3 months ago Your ananolgy of a Republic as representation for our cellular collective is good, however what may be keeping the cells cooperating to the goals of the human or animal may have more to do with the state of bio-electric fields that surround all our cells. I would urge everyone to review the work of Prof. Michael Levin of Tufts University. It would be fascinating to see the effects or rather the relationship of various supplements on cellular bio-electric fields. Reply @flawlesscomplex @flawlesscomplex 3 months ago I wonder if anyone here has experienced the side effect. I was taking resveratrol, then direaha happened, and then the doctor found blood in my stool. After many scans, they found nothing wrong but it was the supplment. My stool returned to normal after I stopped taking this supplement. After a few months, I thought I tried to retake a resveratrol supplement, and the same thing happened! Reply 10 replies @ccamire @ccamire 3 months ago Thanks for the info. I expect to continue to drink my red wine without any stress. 1 Wellness Messiah with Rimon Reply @nick711ful @nick711ful 3 months ago Take that, don't take that. Take the other, don't take the other. Take less, take more. It makes sense. It doesn't make sense. Do yourselves a favour and save your hard earned money. Enjoy your life and do what makes you happy. A short, happy life is much better than a long, miserable one. 2 Reply 1 reply @create-a-state @create-a-state 3 months ago I have some 170mg resveratrol capsules. Do you think these will be OK for me to take twice a week? Noticed this was close to the 200-500mg medium dosage 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @NarutoIsTheRikudou @NarutoIsTheRikudou 3 months ago I’m around 6ft and 143 pounds. What dosage would you recommend at this size? Reply 3 replies @soniahaydee868 @soniahaydee868 2 months ago Wow 👍❗️thank you for such and important information ❗️👍 Reply @theancientsancients1769 @theancientsancients1769 3 months ago This explains why I often get palpitations when I take at around 500 mg I tolerate 100mg the best 2 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 3 replies @lyingeyes6000 @lyingeyes6000 3 months ago Every time Dr Sinclair states his daily regimen he says he takes 1g per day. Maybe he learned something new? 1 Reply @darlingwolf21 @darlingwolf21 1 month ago You frequently reference 'low dose' and 'high dose' – does low dose constitute 500mg and less? High dose, above 500mg? Reply @MixtrisUFOimages @MixtrisUFOimages 3 months ago very informative. thanks 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @williamx0 @williamx0 3 weeks ago So I’m eating 100grams of blueberries per day which equals 5mg of resveratrol daily. Should I still supplement with resveratrol cuz 5mg daily is too little if I want to target longevity? Reply Wellness Messiah with Rimon · 2 replies @lyingeyes6000 @lyingeyes6000 3 months ago Cell death in cancer cells alone, or were there regular healthy cells too? What was there outcome. Reply @supercal333 @supercal333 2 months ago (edited) At 32:00 the 2022 study also says low dose Resveretrol can induce autophagy of senescent macrophages as well as promote cell viability and proliferation. These appear to be opposite effects. The effect on senescent macrophages is contrary to the point you are making. Can you comment on this please? Reply @levinelson3508 @levinelson3508 3 months ago The question I have does low dose resveritrol help cancer grow by stopping the body’s inhibitory process? 1 Reply Wellness Messiah with Rimon · 2 replies @simoncurtis3779 @simoncurtis3779 3 months ago Informative but this should be a 20 minute video 😅 Reply @pavanlulla @pavanlulla 3 months ago Ok so combine low with occasional high dose? 2 Reply Wellness Messiah with Rimon · 1 reply @gloriagolemboski4515 @gloriagolemboski4515 2 weeks ago What is low and how many days a week should we take it. 1 Reply @markvoelker6620 @markvoelker6620 3 months ago So resveratrol in high doses induces cells to kill themselves by activating the apoptosis program, by creating a signal that causes the cells to think they have been heavily damaged and therefore need to be killed and removed instead of repaired. Okay. But then, why would taking high doses of resveratrol (for example, 5 grams once each day for two consecutive days) preferentially cause cancer cells to commit suicide, compared to healthy cells committing suicide? Do cancer cells have a lower threshold for activating the apoptosis suicide program than non-cancerous cells? A few years ago I participated in a clinical trial designed to evaluate the efficacy of the senolytic combination of quercetin and dasatinib at preferentially killing senescent cells. The dose I took was 0.5g dasatinib + 5.0g quercetin, once. After three such dosing regimens, spaced 6 months apart, the osteoarthritis in my knees disappeared. Perhaps the optimal way to use resveratrol and other similar compounds, is to take low doses daily or every other day, and every once in a while, take a high dose prophylactically to clear out cancerous and/or senescent cells. Here I would say a low dose is about 250mg and a high dose is 5g. Reply @mieciuuu506 @mieciuuu506 3 months ago So how better to take this Resveratrol every day or what? and what dose is best? 1 Reply 4 replies @moisuir385 @moisuir385 3 months ago (edited) Really enjoy your videos.anything on spermidine and Apple cider vinegar? Liked and subscribed 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @marktapley7571 @marktapley7571 3 months ago Cancer is caused by a deficiency of vitamin B17. Cancer cells are just regular cells that remain juvenile (indeterminate) and fail to mature into a specific (determinant) type. Cancer therefore is a metabolic disease and cannot be cured by chemotherapy, radiation or surgery except only ap. 4% of types (childhood leukemia). Animals and humans who consistently maintain adequate levels of B17 in the diet did not get any form of cancer. All forms of cancer involve the same process. Read G.Edward Griffin’s book “World Without Cancer." Reply @milagrosroman9978 @milagrosroman9978 3 months ago i have diabetics and am off the pills, I have it under control through fasting and diet, can i take this pill? Reply @kenswanston820 @kenswanston820 3 months ago 71 yrs 6'4" 220lbs with a CAC scan of +1000 and a GP who wants me on statins. Recently started daily taking K2/MK7 (300mcg) with D3 X3 (25mcg/1000IU) instead and NOW's Resveratrol (200mg) along with LOTS of other OTC supplements. I currently have no sign of cancer but Dad (not sure what type) and a brother (who had Large B-cell Non-Hodgkins lymphoma - survived!) had it. Should I take 1 gram sequentially (i.e. every day for a week once a month)...or? Not taking NMN, but should I? Any other health/longevity suggestions for a semi-active old fart would be MUCH appreciated! Thank you for the great info! Reply @aclearlight @aclearlight 2 months ago It is unfortunate that you continue to platform and Sinclair. That greedy, treacherous, back-stabber is no friend of the common man. His concern is great wealth, whatever it may do to the public health. He has proven this in spades by getting NMN jerked away from us all so that a tiny number of wealthy clients might one day take his "drug". Reply 2 replies @renatabarros1065 @renatabarros1065 1 month ago Im a nutritionist from Rio de Janeiro. ❤ Reply @lyingeyes6000 @lyingeyes6000 3 months ago Maybe then high dose to start, to kill any cancer cells, then switch to low dose for longevity? Reply @BryanDalleStelleOfficial @BryanDalleStelleOfficial 3 months ago Hey Rimon, are you taking NAC as well? If so, how much? 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @DaskaiserreichNet78 @DaskaiserreichNet78 3 months ago Interesting David Sinclair takes one gram a day where as David Sinclair father only takes a pinch of resveratrol. Reply @jefftezos @jefftezos 2 months ago Do you have any videos that cover Apegenin? Reply @farmerjohn6526 @farmerjohn6526 3 months ago Well, if less is best, maybe none is better. Reply @docflyer4001 @docflyer4001 3 months ago Can you please place references for your research studies you quote? No I idea who is publishing these studies by your video. Reply @georgechristoforou991 @georgechristoforou991 3 months ago 22:41 You say you would never take low dose resveratrol if you had an active tumor. But didn't the research state there was no inhibition of cancer cells not that it induced an increase in cancer? 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @user-wg6cj2lh5f @user-wg6cj2lh5f 3 months ago (edited) Only intermittent fasting works better for longevity! I will never take resvera trol . Reply @badhairballer23 @badhairballer23 3 months ago (edited) Next time be aware and please mention which of the studies have been in vivo and which in vitro, for it makes a big difference!!!! in the interpretation of the findings. Reply @wilsont1010 @wilsont1010 1 month ago What is the purpose of taking this? 1 Reply @PedroGuzmannimbus @PedroGuzmannimbus 3 months ago Not clear if it is good to take low dosage, or is better to prevent cancer at high dosage?? 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @davidboyle1193 @davidboyle1193 3 months ago I take 1 gram per day , is that to much 1 Reply @robertferguson7800 @robertferguson7800 6 days ago So how much should I at 72 should be taking Reply @eyeswideopen7777 @eyeswideopen7777 3 months ago One gram is too much. Won't your liver or kidney be poisoned Reply @edenposh1890 @edenposh1890 3 months ago thanks fort the video. however I did not understand our statement at the end of the video...if you were old ypu ''would take every quarter for one day''???'what does it mean? high dose per day? 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @thehungergames8918 @thehungergames8918 1 month ago I am a bit confused 🥴 2 Reply @andreamazzaferro5168 @andreamazzaferro5168 3 months ago ok great - what s a low dose the n? 2 Reply @lionofgod9 @lionofgod9 1 month ago (edited) YOU ATE RESVERATROL FOR 3 YEARS NOW?................SO............DO U HAVE SUPERPOWERS OR CHANGE YOUR NAME TO MATUSALEM (HE LIVED 900+ YEARS)? 1 Reply @emmasnow29 @emmasnow29 3 months ago I don't see good quality evidence that Resveratrol has any effect on lifespan. Reply 4 replies @chriswhitaker8467 @chriswhitaker8467 3 months ago Hmmmm.. I did more research than this guy, and I disagree with his assertions! Also, studies on NMN and Transreveratrol, which is the active ingredient in Resveratrol. 1 Reply @dianamayfield5615 @dianamayfield5615 3 months ago Tally Health, one of Sinclair's companies is offering a supplement with the following - CAK 1000 mg, Resveratrol 500 mg, Quercetin 500 mg, Fisetin 100 mg, and Spermidine 900 mcg... Note there is no NR or NMN... 1 Reply @reiinboundstrategist @reiinboundstrategist 3 months ago What's the summary? This is way to long. 1 Reply 3 replies @Will-dz9nl @Will-dz9nl 1 month ago Don’t waste your money. Reply @maliksay1 @maliksay1 8 days ago Very confusing, made no sense. Reply RESVERATROL & David Sinclair: Shocking Detail and Big Mistake - episode 1 Wellness Messiah with Rimon 36.4K subscribers Join Subscribe 3.1K Share 130K views 4 months ago Resveratrol. A molecule. A supplement. Resveratrol, popularized by Dr. David Sinclair, is one of the most controversial yet fa … 304 Comments rongmaw lin Add a comment... @WellnessMessiah Pinned by Wellness Messiah with Rimon @WellnessMessiah 4 months ago (edited) ✅ Check the special deal of habits creation app + my routine for longevity: https://wellnessmessiah.com/app Disclaimer: I'm an affiliate of the company - I trust their product. Buying will support my channel 10 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @dcjohnson2208 @dcjohnson2208 4 months ago (edited) As an old retired scientist (octogenarian) I appreciate the efforts you expend in your research and interpretation of same. Your presentation level is excellent! I too have been taking David Sinclair’s protocol. I immediately backed down from 1 gram to 250 mg and then moved to 500 mg every other day. I have found from my own body reactions, tests etc. That a mostly vegan diet + 500mg NMN daily + 500mg Resveratrol every other day gives me the best results over the past 19 months. I’m forming an opinion that 36 hour fasting is going to be best for me. I usually have 2-3 tablespoons of EVOO when I break my fast. I have never smoked, drank alcohol or used illicit drugs. Today is my father in law’s 103rd birthday. He still gets around by himself. He played tennis 2-6 hours/ day for 82 years before he stopped at age 92 because he couldn’t keep up with the younger men! 185 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 34 replies @stevecrawfordpianodreams5167 @stevecrawfordpianodreams5167 4 months ago Thank you very much for this in depth analysis of the available data. I'm glad you are doing the episode 2 on this topic because I kept thinking why is Dr. Sinclair taking 1 gram a day when the analysis so far points to a lower dose being the most effective dose. I look forward to the upcoming episode. 24 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 4 replies @Jacob-uv1kh @Jacob-uv1kh 4 months ago (edited) Please keep making content. You're one of the very few people who can put out a 40 minute video that I can watch every minute of. Thank you 40 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @es1653 @es1653 3 weeks ago I absolutely love this continuing free education on ageing backwards and becoming younger. I started taking 400 mg. Resveratrol daily along with my other supplements and vitamins. Reply @harborgirl8877 @harborgirl8877 2 months ago I am convinced that centenarians do have a genetic component. My family, especially on my paternal side, has consistently long life spans. My father (born in 1917) lived to be almost 100, but so did my grandfather, and great grandfather. We have gone back to the 1700’s, and were shocked to see how long people in our family line lived. This was during a time when life expectancy was far less. I am hoping good genes, and following a good anti aging lifestyle will get me to 110-120. As I said, both my parent died shortly before 100, and both were active and sharp minded. 11 Reply 6 replies @AT-xl9db @AT-xl9db 4 months ago What a great podcast, and this makes perfect sense along with your other videos on resveratrol…I’ve been microdosing and pulsing it ever since! 8 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @mathlibwis @mathlibwis 3 months ago Fascinating well-researched video. I read that high doses of resveratrol blunts the benefits of exercise. I assume that if I exercise 4-5 times a week in the morning, engage in intermittent fasting with the main meal in the afternoon, along with a glass of wine about every other day, I will receive nearly the maximum benefits of all three. Thanks 5 Reply @semaaral2498 @semaaral2498 3 months ago Thanks, a lot for this informative podcast. Yes like you've heard me. I've read these results and was worrying a lot. So hard to find a spoon with 80_100 gr to calculate but find a way to calculate. The original spoon is 250 mg which comes with the powder from # donotage I think of your wife & sending my prayers. Looking forward to seeing you together again. She is young so with your super care will heal one day, hopefully.🙏🌹 Thanks for this video. Very useful🙏💙💯🙌 3 Reply 5 replies @bluffmaster4222 @bluffmaster4222 1 month ago Very engaging content ! One of the few people on social media who do their home work before opening their mouth. Keep going ! Lovin' your work brother! Reply @llacerda1982 @llacerda1982 3 months ago Great content, thanks for putting it together! What's your view on the bioavailability of resveratrol in mice vs humans? Could humans need a higher dose to factor in a possible lower bioavailability of resveratrol in humans, but still achieve similar results to the ones achieved with the mice on every other day feeding with low resveratrol? 2 Reply @harborgirl8877 @harborgirl8877 2 months ago Thank you for explaining this subject in a way I could understand. Your research is appreciated! 1 Reply @llacerda1982 @llacerda1982 3 months ago (edited) Following up on my last comment: Besides dose (low or high), it seems that the bioavailability of free resveratrol between rodents and humans needs to be taken into consideration to achieve the same benefits that have been found in the different studies. 38% bioavailability of Resveratrol in rodents, and < 1% in humans is a significant difference that, from my understanding, shouldn't be neglected, therefore needing a higher dose in humans to achieve a similar outcome to the ones referred in the studies. 4 Reply @jimsigrist5506 @jimsigrist5506 3 months ago (edited) Bravo! Very thorough explanation! Thank you very much. More longterm studies necessary. Need to know more about drug to drug (molecule) interactions with NMN, Metformin, Berberine, and Ficetin, etc. 1 Reply @dontaylor8912 @dontaylor8912 4 months ago I really liked this presentation, Rimon. You revealed plenty of useful info. David Sinclair has repeatedly stated that resveratrol is needed to fully activate NMN. He gives the analogy of accelerator and fuel. Low dose resveratrol is helpful for lowering insulin and glucose but is 50 to 120 mg enough to effectively activate NMN? 12 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 3 replies @NTMihaila @NTMihaila 4 months ago I love your channel man! Keep the excellent content coming! 4 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @starfox300 @starfox300 3 months ago Resveratrol is not a bad supplement, there are countless independent studies on it's benefits. It also seems to be an AMPK activator Reply @MrCt40 @MrCt40 1 month ago Thank you for doing the hard work on clarifying this confusing area - which brands of resveratrol do you like to take ? Reply @aljosarojac8575 @aljosarojac8575 4 months ago Great investigative work. Well done 👍 2 Reply @slidecatch @slidecatch 4 months ago Great video, thanks! The only solution to the mystery that I can think of is that Sinclair believes that taking high-dose Resveratrol with NMN combined confers some synergistic benefit that low-dose Resveratrol with NMN would not. 11 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @Sublimer79 @Sublimer79 4 months ago (edited) I take knotroot as an natural source (I grind the root into a powder, its also sold in powder form now which would be a lot easier) I would assume its safer since its not just isolated resveratrol. I could be wrong. But that is my source. I only drink 1 bottle of wine a month. I'm sure it does something. 3 Reply @readingwithofer888 @readingwithofer888 4 months ago My grandfather lived until 104 he never took reservatrol , only drink little wine 🍷 every day 24 Wellness Messiah with Rimon Reply @CamiloVergaVideos @CamiloVergaVideos 4 months ago Thank you very much for the video and analysis! It is very interesting! But I think there is something very important that is not being mentioned. When doing the test tube studies with cells, sugar and resveratrol there are no problems with bioavailability. The question, in the case of humans, is how long a capsule or powder reaches the cells after passing through the intestines. Maby a dose close to a gram is necessary for some of it to reach the cells. Thank you very much and greetings from Buenos Aires. 8 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 3 replies @MyMy-tv7fd @MyMy-tv7fd 4 months ago rather too complicated for me I am afraid, but I am excited to see that resveratrol is still being researched 9 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 3 replies @jeannineosorio6566 @jeannineosorio6566 3 weeks ago Good evenig Rimon! I have recently added NMN and TMG. I currently weigh 125 lbs. How much resveratrol could I begin taking? Thank you and I look firward to your next video. Reply @sozikurd7400 @sozikurd7400 1 month ago (edited) Thanks a lot ❤❤❤❤❤❤🫶🏼🫶🏼🫶🏼🫶🏼🫶🏼🫶🏼 I have taken 500 mg almost everyday with the weekend off, and I have taken resveratrol totally wrong! I’m intermitted fasting at least 16 hours and took resveratrol in the morning and about an hour before NMN It has been huge changes with my energy in a positive way but I have gained weight , about 5 kg since last year 😢 Reply @pjaworek6793 @pjaworek6793 4 months ago Thank you, so much detailed information. I'm eyeballing for about 50mg every other day from a 600mg (50%) pill. 2 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @JaxObsessed @JaxObsessed 4 months ago Thank you Rimon!! This is useful information. ... On a side note, I hope your wife is continuing to recover. 10 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @MP-id2po @MP-id2po 4 months ago Interesting how red wine as an explanation for the French paradox, has triggered thousands studies in resveratrol. Great job in abstracting and gathering relevant information from all the studies to create order, logic and relevance from all the "chaos" 14 Wellness Messiah with Rimon Reply 4 replies @bilbyguy2389 @bilbyguy2389 4 months ago What a great video. I am fascinated. Well done on all your hard work.😀 2 Wellness Messiah with Rimon Reply @dude861 @dude861 4 months ago I wouldn't consider red wine as "low dose Resveratrol". Considering the studies on mices etc as well as your interpretation you would consider the optimal dose roughly around 100 mg Resveratrol a day for fat/unhealthy people or every 2nd day for healthy, normal people. Red wine has roughly around 1mg per glass. So putting them into the same group does not make sense to me since it has FAR LESS Resveratrol than all the other studies (were i think the lowest doeses were around 33mg). Reply @Sunyataji @Sunyataji 4 months ago Going by the graphs and estimating the number values, it seems that EODLR is an approx. 2.3% increase and HCLR is 1.4% increase in longer lifespan. Transposing that to a human lifespan of 80 yrs, would be 1.8 yrs and 1.1 yrs gain in lifespan respectively. Granted, we would all like as long a lifespan as possible and even 1 year is desirable, but given other factors effecting lifespan is the low vs high resveratrol question that significant? 8 Reply @TheMarczan @TheMarczan 3 months ago Great job! Thank you so much for this video! :) 1 Reply @vivian3371 @vivian3371 2 months ago I am RAW frutarian for a years...red seeded grapes are my must have every day. 1 Reply @masterjstory7887 @masterjstory7887 4 months ago Absorption is key. Our body chemistries are unique. We were taught at medical school that B3 (NMN) must be taken in conjunction with the vitamin B group for it to be metabolized, otherwise it is excreted. 5 Reply 1 reply @HughChing @HughChing 3 months ago Post-science claims that DNA is designed for permanent existence and, therefore, it is impossible to have conclusive drug test (solutions in social and life sciences must be accepted by complete mathematical or logical rigor). There is also the concern of anti-Epigenetic effects. Thank you for the detailed presentation. 1 Reply 2 replies @rebeccaortman4764 @rebeccaortman4764 4 months ago Rimon, how can I measure resveratrol when I bought it in bulk? I have measuring spoons 1/8, 1/16, 1/32 of a teaspoon. I don't have a sensitive scale. Any ideas? Thank you for doing the math on dosage according to our body weight. 1 Reply 4 replies @havad3938 @havad3938 3 months ago Excellent analysis! Did they compare the mice, or people to those that did not take any reseveratrol? Perhaps im missing something. thanks 1 Reply @paj6757 @paj6757 4 months ago Very well explained and practical. 1 Wellness Messiah with Rimon Reply 2 replies @lynamine @lynamine 4 months ago Excellent podcast! 1 Wellness Messiah with Rimon Reply @dimka11022011 @dimka11022011 3 months ago what an informative video! if someone is looking for a human subject for the study of resveratrol - I volunteer =) 3 Reply @carloscarion1748 @carloscarion1748 2 weeks ago (edited) Pinot noir has the highest concentration of resveratrol. It has the hardest working grape. also muscadine grapes and açaí berries, as well as organic peanut butter, or boiled green peanut( a southern delicacy), and the common knot weed 1 Reply @N330AA @N330AA 4 months ago (edited) Yeah great vid. I think Sinclair was a bit defensive and uncourteous in that clip. It's really the calories restriction/fasting that did the bulk of the life extension for those mice. I don't think he was expecting the outcome which showed low dose is better and also that resveratrol isn't such a gamechanger for people already leading a healthy lifestyle. As it happens i do in fact do alternate day fasting and CR, so I'll add a low dose resveratrol on the eating days. 2 Reply Wellness Messiah with Rimon · 1 reply @emilguste @emilguste 4 months ago Really good work mister, looking forward to the next 2 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @bilbyguy2389 @bilbyguy2389 4 months ago (edited) A quick question; Is the low dose a daily dose or every second day? I think I heard Dr Stanfield saying he does not take it on the days he exercises. Do you have any info' in this regard. Thank you so much. This ride in like a Tom Cruise movie! But your video has more longevity 😄 8 Reply Wellness Messiah with Rimon · 1 reply @RestorationAuto @RestorationAuto 4 months ago (edited) I think you need to recheck your calculations at 10:23 where the low dose is stated as 4.9gms/kg which would equate to 490gms for a 100kg (220lb) individual (4.9 x 100 = 490) so a 160lb person would need to be taking 350mgs/day to be on an equivalent low dose. I take 400mgs/day. Also, Resveratrol should be taken with something that has fat in it as it is fat soluble. David takes his with his morning yoghurt, whereas I take mine with my morning glass of Bonsoy soy milk. NMN on the other hand should be taken with water on an empty stomach as it is water soluble. I take 1000mgs of NMN with a glass of water first thing in the morning. 12 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 4 replies @reikiandrew @reikiandrew 2 months ago Can you please tell me if NR/NMN + resveratrol and GlyNac work in similar or complementary way? is it ok to take both combos? 2 Reply @dmpag7000 @dmpag7000 1 month ago excellent and very thought provoking Reply @jstntowner11089 @jstntowner11089 3 months ago What is your opinion on Resveratrol vs Trans-Resveratrol? Is one gonna make a difference over the other or is that just supplement manufacturers trying to market their products to sell more? 1 Reply @donkeyhota.dontflamingo9294 @donkeyhota.dontflamingo9294 4 months ago Hay Rimon, if a guy doesn't follow your longevity advices for the first 60 years of his life and start applying them when turns 60, and another guy was applying your advices on longevity for the first 60 years of his life and stopped doing it once he turned 60, who of both do you think has more chances to live longer? 2 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @michael1rarezebra560 @michael1rarezebra560 3 months ago Thanks for the in-depth review Reply @brazilchem @brazilchem 4 months ago I do low and intermittent resveratrol dosage in the form of 1 bottle of red wine at once, per week. 11 Wellness Messiah with Rimon Reply @emil8367 @emil8367 4 months ago It is simple. He (D.S.) is not wrong. He knows exactly how much is needed to prolong longevity, but selling much more is more important to him, to spread information. Reply 2 replies @NTMihaila @NTMihaila 4 months ago (edited) Didn't you already make a video talking about how low-dose cycled resveratrol is ideal? Around 100 mg daily, a few days on, a few days off. I recall you talking about how low-dose resveratrol restores senescent cells. 4 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @drieman @drieman 4 months ago Sorry, busy person here. Maybe you can summarize your findings, and not have your viewers struggle through the data and your interpretations. However, keep your findings coming. Thanks 6 Reply @fwdolphin @fwdolphin 2 months ago You are very thorough and so much so it made my head spin. I just wanna know how much to take for someone that weighs about 200 pounds. Reply @cityinthesky1341 @cityinthesky1341 2 months ago Dr. David Sinclair said that determining human dosage based on mouse dosage involves total surface area for the calculation. It is not a simple weight ratio formula. 1 Reply @507thug @507thug 3 months ago Insightful!!! Thank you Reply @mikec5544 @mikec5544 3 months ago (edited) QUESTION. What about Trans-Resveratrol? My reading seems to indicate that Bioactive Trans is more effective. So if we buy into this 30-100mg low dose resveratrol, how would this translate to the Trans version in terms of dosage? 2 Reply @benjiebarker @benjiebarker 2 months ago The 30 years of his resveratrol, nmn, intermittent fasting, exercise, and diet are proof for me…he looks younger than all the other fudsters Reply @papyber @papyber 4 months ago Great job, thanks. Reply @edouarddebonneuil149 @edouarddebonneuil149 3 months ago Isn't resveratrol is quasi not absorbed by the body? In the specific study, isn't it the control that is short lived? If large doses of resveratrol lead to a lower lifespan, isn't it because some is absorved? My questions might be naive, but I prefer to make sure we get things right Reply @rossnrice @rossnrice 2 months ago Thank you for the update. Reply @CommanderRiker0 @CommanderRiker0 4 months ago Best presentation yet 1 Wellness Messiah with Rimon Reply @rolandbrecher4265 @rolandbrecher4265 2 months ago So what is considered as "low" dose resveratrol? Most of the Supplements have at least 500mg of resveratrol, is this considered as "high" dose? Should I avoid taking them? 1 Reply @ezragabay7686 @ezragabay7686 2 months ago I took it every day and made me tiered so now i take on days i don’t workout. Or every other day no matter what. Reply @pepeponcela @pepeponcela 4 months ago Rimon, here's the problem: videos 45mn long are a non starter, particularly when you start talking about some study in rats from Sinclair... more than 15 years ago. Take a leaf from Brad Stanfield: if you can't condense someone else's research in less than 10mn, might as well read the paper. Sinclair: it still amazes me how much credit this guy has. He made a fortune on a resveratrol research that was not replicable in 2006... and ignores all thr research since then. Great stuff. 8 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 4 replies @thelasthallow @thelasthallow 2 weeks ago (edited) the only thing that sucks is that there are tons of companies out there making these products and its hard to say which one is the best, for Resveratrol, all i know is it should be white and crystilline, thats the only way you know its good supposeldy. my first product i bought from walmart (yeah i know dumb) was a freaking liquid, so now ive pulled out the shotgun and spent over $60 on 3 different brands to see which one meets those 2 criteria. ive tried looking online for reviews but this is all new to me so im not sure what websites to trust or what brands are the best since most people that take these suppliments dont actually know that much about what they are taking. Reply @elliottrubenstein1746 @elliottrubenstein1746 4 months ago Great information. Reply @mieciuuu506 @mieciuuu506 1 month ago Hey, how much resveratrol to take for a person who weighs 90 kg? is Japanese Knotweed Extract or Pure Trans-Resveratrol Better? Reply @SeattleCondoSpecialistcom @SeattleCondoSpecialistcom 3 months ago Bravo. Great Information! Reply @user-jx2ee7dk4l @user-jx2ee7dk4l 2 weeks ago I say an interview with David I think it was one of the Lifespan videos or Huberman Podcast he said the calculation of mice weight and human is not 1 to 1 based on our weight differences it was actually lower. I don't remember the percentage he said to use I am not totally sure but I think it was 4 to 1 Reply @raibalama @raibalama 4 months ago (edited) I think the basic problem is sugar which is new for humans so get rid of sugar and all carbs in your diet and you do not need any compounds that reduce sugar in your body. I advise my patients who are obese to avoid 4 items: bread, rice, basta, and all sweets. 3 Reply 4 replies @KThalman @KThalman 3 months ago Sinclair has publicly stated that the initial claims around Resveratrol are flawed. Of course he made those statements after he sold patents for those studies. Reply @zackbarkley7593 @zackbarkley7593 2 months ago (edited) It's interesting but not really translatable to humans. In general, but it radically varies, mice have 5x higher metabolism than humans, so you would need to reduce the dose even more...and this is actually done in phase I trials. If this is some kind of effect that requires a nondrug phase to work, then you might also need to change the time on time off...for example 5days on 5 days off. We just don't know though and it may depend on other factors than just metabolism. Reply @33Crazydude @33Crazydude 4 months ago Wow, what a great video 💗 3 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @joannsmith9 @joannsmith9 4 months ago Bravo! Brilliant!! 1 Reply @drunvert @drunvert 1 month ago (edited) Remember, mice have a 6x metabolism. So every other day is EVERY 12 DAYS for humans. That's almost a two-week fast Reply @Skiskiski @Skiskiski 2 weeks ago Thank you. I stopped taking resveratrol. 1 Reply @dantwister5106 @dantwister5106 4 months ago (edited) I only care about resveratrol and quercetin because they increase the effects of caffeine. The idea is taking low dose caffeine every other day to prevent tolerance. What does caffeine do? It makes running and working out easier. Why working out? To be healthier and to live longer. Probably I will also need piperline (black pepper) to increase the bioavailability of resveratrol. 2 Reply @MrHlynskyy @MrHlynskyy 2 months ago Wow you just converted my 2 month supply to 2 years supply. 2 Reply @christopherroantree5542 @christopherroantree5542 2 weeks ago I wonder why the leading researcher on longevity and aging at Harvard takes 1000mg resveratrol if his own data on mice suggest lower doses are more effective for his needs. Just seems odd he that he would disregard all his own data and in fact from what you suggest earlier potentially shorten his life with a higher dose. Very odd need to clarify his exact reasons/arguments for personal/human 1000mg daily consumption. Great video but baffles me why Sinclair would ignore his own research if this is truly the case. Need to hear his own scientific reasons for 1g 1 Reply @jackd9820 @jackd9820 3 months ago Rimon, I am 71 years old and one of those seniors who exercises every day ... elliptical, resistance, swimming. Since taking Revesterol before exercise is not advised am I OK with taking it after exercise on each of the 5 days with a breakfast meal? 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @jackaiki @jackaiki 3 months ago Thank you 💪🏾 Reply @jgs9911 @jgs9911 4 months ago Another excellent video. Thank you. BTW: your English is perfect Reply @0906mlynek0906 @0906mlynek0906 3 months ago Hi, I don't know English, tell me is it better to take a little Resveratrol or a lot? weighing 90 kg? And is it better every day or every other day? Reply @SPX3455 @SPX3455 3 months ago The mice graph says +7% longevity on low dose reseveratrol compared to no resveratrol. I.e. +5 human years Reply @10jamespv @10jamespv 1 month ago Hang on. a dose of 4.9mg/kg per day should translate to a dose of 342mg per day in a 70kg person (approx 160 pounds). Reply @constantinepatsalos2243 @constantinepatsalos2243 4 months ago I love your channel ❤ But why we waisting time try to prove Dr Sinclair wrong? 2 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @say6837 @say6837 4 months ago (edited) Is fasting and taking low dose resveratrol on the same day more effective than just fasting? 1 Reply 1 reply @1fires1 @1fires1 3 months ago Isnt it about absorption rate? So a higher dose would at least somewhat guarantee the lower titration rate? Reply @josephshawa @josephshawa 3 months ago So what exactly are aging genes? How is it resveratrol stopping their expression specifically? Did I just miss it? Reply @nathansaruri9262 @nathansaruri9262 5 days ago so just to confirm we’re supposed to take resveratrol every other day? And we have to go based off of the calculation provided to us for our body weight? Reply @fishnski9211 @fishnski9211 2 weeks ago Has anything been discussed on astaxanthin? Reply @reinerheiner1148 @reinerheiner1148 4 months ago I highly doubt that we can simply convert dosage from animals to humans, because absorption of resveratrol is very different between humans and animals. Thats why we see a lot of positive data from animal studies but the picture is a lot worse for human studies. So unless you account for the difference in bioavailability between humans and animals the conversion is plain and simple wrong. 2 Reply 1 reply @JenP2776 @JenP2776 3 months ago Cannonau grapes/wine from Sardinia has the highest level of resveratrol! 1 Reply @antykom1 @antykom1 4 months ago To be able to put up with hundreds of drunk nuns twice a day for so long you need to be a God! 1 Reply @KThalman @KThalman 3 months ago excellent video Reply @Lasertop @Lasertop 4 months ago So if a Low dose is the way to go, why is Sinclair taking a 1-gram daily dosage? 3 Reply 4 replies @gradivaciani9673 @gradivaciani9673 2 weeks ago What if the bioavailability is different in mice and humans? Reply @ohfft @ohfft 3 weeks ago (edited) Anyone who has a small amount of knowledge is much more dangerious than a fully knowledgeable person, especially one who calls himself a Messiah! That alone should send red ligh warnings to anyone watching this! 1 Reply @MrPaulFabian @MrPaulFabian 4 months ago Presumably the benefits of resveratrol in de-alcoholised red wine would be the same as red wine? 2 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @patrikbjorling4391 @patrikbjorling4391 3 months ago So theoretically we can reach the age of 160 to 180😂😂😂😂 Reply @bradcoffman2607 @bradcoffman2607 2 months ago Maybe I'm missing something here but a 160 lbs person would be about 72 kg. 72 x 4.9 mg is roughly 355mg. Where is he getting 30 mg for a 169 lbs human at. Reply @mysimon2003 @mysimon2003 2 months ago Can someone post a summary here 🙏 Reply @ToddHoff @ToddHoff 4 months ago It seemed like drinking two glasses of red wine captured all the benefits? It didn’t see a dose response curve to indicate if half a gram was x times better. 1 Wellness Messiah with Rimon Reply @its1me1cal @its1me1cal 4 months ago Every other day for mice so what’s the equivalent for humans? I’m sure as mice live much shorter lifespans, it wouldn’t be every other day for humans. 3 Reply @pecent @pecent 4 months ago I doubt that the dose being taken is actually biologically available. In that sense, Dr. Sinclair may not be necessarily wrong! ;-) 2 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 3 replies @mieciuuu506 @mieciuuu506 1 month ago The Visanto Resveratrol Liposomal brand has the best quality in the world supposedly Reply @mikecar52 @mikecar52 3 months ago Having to pay you $17 to find out your resveratrol/supplements brands is incredibly mean. Reply @kesiamolina9927 @kesiamolina9927 2 months ago So how much is the intake? Reply @clementwong2319 @clementwong2319 4 months ago To me, it is against intuition to take a supplement that is so complicated: less dose is better… and taking it every other day… What about taking every other 3 days?😂 There is no end. Fasting and exercise works best, as proven by science and by intuition. 3 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @lventer165 @lventer165 3 months ago What about SALVESTEROL? Please tell me your thoughts on this 1 Reply @karenolianti4972 @karenolianti4972 3 months ago I am wondering about the conversions of weight you made from mice to human. In dr Sinclairs podcasts he does say the weight conversion is anything but direct. In fact, a mini pig has the same 'weight' as a person, it depending on a number of factors and there being an established scientific ratio between different lab animals and human beings, quite unrelated to weight to weight. I do not understand your conversion. If you can better explain your conversion from mice to humans I would better accept a change in dose. Reply 1 reply @mikeymileos @mikeymileos 1 month ago If it's 4.9mg per kg then how do you get 30mg for a 160lb person? 72.5kg x 4.9mg is ~355mg Reply 1 reply @jefftezos @jefftezos 2 months ago Whats a good optimal A1C? Reply @unboximage1292 @unboximage1292 4 months ago your best video, I think. LOL 4 Wellness Messiah with Rimon Reply @Seeker_of_sense @Seeker_of_sense 4 months ago (edited) None of these survival curve diffreneces look impressive. If you take resveratrol for decades, you get to live 1 month longer if you are lucky, but spent thousands of dollars. In the end, who cares? Unless there's something better that comes along, I'll give it a pass. 2 Reply 3 replies @theluckyman74 @theluckyman74 3 months ago The only problem, is that, Regular Exercise, can also, increase longevity, but are they, synergistic or, the opposite Reply @ingridsuhr993 @ingridsuhr993 3 months ago I take 125 mg lipo trans-resveratrol. 1 Reply @markpappas9858 @markpappas9858 3 months ago Is Trans- Resveratrol fine to take??? Reply @supercal333 @supercal333 2 months ago So de-alcoholized wine is better? Reply @raibalama @raibalama 4 months ago sorry to say that D. S. turned from a sincere scientific adviser to a commercial pharma when he figures out that what he is doing has a financial reward. what a pity! 1 Reply @martinsinclair177 @martinsinclair177 3 months ago I take 2-3 grams every morning and night Reply @caulfieldmj @caulfieldmj 4 months ago Is a Mouse day equal to Human day 🤔 I don’t think so. Maybe a mouse day equals a human week or month? 6 Reply @tomg5405 @tomg5405 2 months ago you take conclusions too fast, you can not compare reservatrol and red wine as in red win are more polyphenols not just resveratrol, so you can't know which one works. Reply @waynecaissie1167 @waynecaissie1167 2 months ago resveratrol? Where do you even buy this supplement Reply @Elaba_ @Elaba_ 4 months ago Conclusion: nuns like alcohol. 4 Reply @whiteninja9481 @whiteninja9481 4 months ago Screw all this. I eat walnuts. 2 Reply @FG-dw9cf @FG-dw9cf 2 months ago How much resveratrol is in a cup of itadori tea? Reply @tawacin @tawacin 4 months ago Can we buy resveratrol over the counter pr need doctor prescribes ? 2 Reply 1 reply @JorgeGonzalez-ui3nb @JorgeGonzalez-ui3nb 3 months ago Then, Sinclair, first find a supplement that turns you into a mouse,. 1 Reply @jamiesouza @jamiesouza 3 months ago Why would David Sinclair take 1 gram of resveratrol and go against your interpretation of his own studies? Reply @mixalis6168 @mixalis6168 3 months ago Sinclair put a patent on his sups, who ever makes them, he gets paid!! This is a con !! Reply @goodphone156 @goodphone156 4 months ago Why you say this thing? What proof do you have to say such a thing? Reply @tesekkur @tesekkur 2 months ago I don't take as information anything that comes out Dr.Sinclair and Dr.Huberman's mouths. Dr.Sinclair talks about longevity, health all that and then drinking Coke everyday, because the one he drinks is ' diet coke' and drinks beer and other alcohol every day. Get real! Reply @investidorint @investidorint 3 months ago Why believe a Harvard Ph.D. if I can believe a YouTuber? Reply @NTMihaila @NTMihaila 4 months ago 40:35 As you said, makes absolutely no sense at all. Reply @benjiebarker @benjiebarker 2 months ago (edited) 1:50 Dr brad stanfield looks so old for his age lol…thats what you get for not taking the fountain of youth supplements Reply @patforbes22 @patforbes22 3 months ago It's YOU AND ME. Reply @bm5906 @bm5906 3 months ago You can do without those annoying 3 second "music" separators. 1 Reply @jorgedore5499 @jorgedore5499 4 months ago The problem with His presentation is DR Sinclair is nothing shore of shister , lier, and other .... 1 Reply 1 reply @jonathonperino8681 @jonathonperino8681 3 months ago Whar about Berberine or the prescriptuin Metformin.. Reply @nigelspring-benyon2714 @nigelspring-benyon2714 4 months ago 999999999999999999999999999999999999999oòooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooòooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooòòooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooòòooooooooooooooooooiiiiiiiiiiiiiiiooiooiiioììiiiiìiiiììoiiiììooióooóiioooooooiooooooooooooioooioooioooooooooooooooooooooooìiiiiiiioioioooooooooooooooooooioooioooooooooioooioiiiiiiiììiiiiiiiiiioiiiiiiioiiooooììiiiioiiiooioooooiooiooiooooooooooiooooooìiiiiiiiiiooooooiiìiiìiioooooooiioooooooiioiiioioiiooooooooooooooooooooooiioóìiioiioiiiiiooooooooooìiooooooooooiooiooooooooooooooioooooioooooooooooooooooioooooooooooooooooooooiiìiiioooiiioooooooiooooooooooooioooooooooooooooioiooooooooooooooìoiooooooooooooooiooiooooooooooooooooooooooooooooooooooooooooooooìioioooooioooooooooiooooooooooioooooooooooooioooooiooooooooioooooooooooooooooooooooìioooooooooooooooooiooooooooooooooooooooooooooooooooóoooooooooooioooooooooiooooooooooooooooooooooooóooooóìóooòòòòóóó88ì8888888ì7777777ìloo Reply @PierreDybman @PierreDybman 3 months ago Any good news about your wife, Rimon? Reply @illeagle8041 @illeagle8041 3 months ago Such a long video to watch for one bit of “ important “ information. Reply @bradcoffman2607 @bradcoffman2607 2 months ago I meant 160 lbs Reply @websit3588 @websit3588 4 months ago nice Reply @NotArtic @NotArtic 4 months ago Is eyes safe 1 Reply @benjaminleask6184 @benjaminleask6184 4 months ago Yeah simple.... Reply @VitalisV @VitalisV 3 months ago FANKS Reply @jonduke4748 @jonduke4748 4 months ago a scam Reply @gudata1 @gudata1 3 months ago 40 min of talking? What is the essence? Reply @santarivera1939 @santarivera1939 3 months ago WHY TALK SO FAST? Reply @mr1enrollment @mr1enrollment 3 months ago this all smells like junk science. Reply @chriswilkes2438 @chriswilkes2438 3 months ago Can't understand you Reply @NotArtic @NotArtic 4 months ago Did you to get trubel with eyes Reply @user-ev7vn4np5d @user-ev7vn4np5d 3 months ago Thank you for your study for resveratrolwhich will follow it will be very helpfull for me to have your 0pinion about N M N which is now very popular thanks a lot Reply @cuervos69 @cuervos69 8 days ago Summary: consume less than 500mg of resv per day. 1 Reply 1 reply @vamrkv @vamrkv 2 months ago Mice to human conversion of dose can not be just based on body weight. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804402/ here is interesting study that might help to get better overview what is high dose and low for humans based on mice experiments Reply AUTOPHAGY ACTIVATION: 10 BEST Exercise Habits to Live Longer Wellness Messiah with Rimon 36.4K subscribers Join Subscribe 972 Share 23,955 views Feb 5, 2023 Exercise for Longevity Did you know that exercising for longevity is different from exercising for performance or for building muscles? Listen, if you exercise incorrectly, you may not gain the longevity benefits you think you’re getting. It is possible to improve your performance and lose weight, without activation of the full power of exercise. Today, we'll cover the 11 habits of exercising for longevity. This way, you too can exercise correctly if your goal is to preserve your youth. ---------------------------------------------------------------------------------------- ✅ Suggest watching next: • AUTOPHAGY ACTIVAT... ---------------------------------------------------------------------------------------- ✅ Become a channel member on Patreon. Join with $1 & get access to the 10 resveratrol habits & earn an honorary mention in future videos. ✅ Upper levels receive my entire supplement routine & brands (worth $100). https://www.patreon.com/WellnessMessiah 00:00:00 Intro 00:02:01 What is “Longevity”? 00:08:15 How Exercise Works 00:10:30 Fitness and Youth 00:15:04 Habit 1: Increase Exercise Intensity 00:19:04 Habit 2: Control Frequency 00:22:46 Habit 3: Train Consistently 00:23:51 Habit 4: Be Active Every Day 00:28:08 Habit 5: Increase Intensity of Everyday Activities 00:31:41 Blood Sugar and Longevity 00:36:28 Habit 6: Exercise after sweets 00:40:26 Habit 7: Eat to Exercise 00:46:05 Habit 8: Exercise All Key Muscles 00:47:57 Habit 9: Aerobics vs Resistance for Longevity 00:50:10 Habit 10: Avoid Over-training 00:53:01 Habit 11: Improve Exercise Recovery 00:55:19 Rimon’s Exercise Routine 01:02:54 All Habits Organized 01:05:41 Exercise & Big Picture ---------------------------------------------------------------------------------------- ✅ The favorite videos on this channel - playlist: • Longevity Favorites ---------------------------------------------------------------------------------------- Study References: https://www.bsu.edu/news/press-center... . Keith M Diaz, Andrea T Duran, Natalie Colabianchi, Suzanne E Judd, Virginia J Howard, Steven P Hooker. Potential Effects of Replacing Sedentary Time With Short Sedentary Bouts or Physical Activity on Mortality: A National Cohort Study. American Journal of Epidemiology, 2018; DOI: https://www.renalandurologynews.com/p... https://www.bsu.edu/news/press-center... https://pubmed.ncbi.nlm.nih.gov/30384... https://bmcsportsscimedrehabil.biomed... https://www.ncbi.nlm.nih.gov/pmc/arti... ---------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------- The Wellness Messiah podcast is available on Spotify, Apple Podcasts, and Overcast. ---------------------------------------------------------------------------------------- Credits: Scott Buckley Disclaimer & Disclosure: The information in this video and/or at this channel is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. It is intended as a sharing of knowledge, educational and information from the research and experience of Rimon, who encourages you to make your own health care decisions based upon your research and in partnership with a qualified health care professional. Rimon is not a medical doctor. If there is a contradiction between the advice here to your doctor or local authorities, always go with the doctor and the authorities. Statements made, or solutions suggested in this video and/or at this channel are not intended to diagnose, treat, cure, or prevent any disease. Chapters View all Featured playlist 18 videos Exercise for Longevity Wellness Messiah with Rimon Wellness Messiah with Rimon 36.4K subscribers Videos About 46 Comments rongmaw lin Add a comment... @WellnessMessiah Pinned by Wellness Messiah with Rimon @WellnessMessiah 4 months ago (edited) 🔴Since 2007, I've researched the best supplements to keep my muscles young, and not age QUICKLY like most athletes. Get my entire routine for free when you buy this app: https://wellnessmessiah.com/app 7 Wellness Messiah with Rimon Reply @samsulamar7139 @samsulamar7139 4 months ago The summary: Exercise for Longevity: 1. Autophagy activation 2. Fitness preservation 3. Flattening sugar level Exercise Habits: 1. Intense and infrequent: - Increase exercise intensity - Reduce frequency - Exercise all key muscle at least once every two weeks - Both aerobics and resistant training - Stay consistent - Keep certain workouts after large meals or sweets - Avoid overtraining too intensely/ frequently  no sore more than 1 day - Improve sleep and nutrition 2. Everyday (low – moderate intensity): - Use fitness level to be active - Increase intensity to these everyday activities - Short bursts of 1-5 minutes of exercise after long sittings - Do something physical after large meals or eating sweets The Ten Commandments of Longevity: 1. Either intermittent fast of cut dramatically sugar and carbs by breaking the sugar dependency. 2. Suppress TOR by avoiding excess protein (essential amino acids). 3. Integrate anti-aging foods that target longevity pathways. 4. Reduce inflammation by replacing cheap vegetable oils with healthy fats. 5. Take longevity supplements at the right timing, dosage and quality. 6. Improve the quality of your sleep, and sleep early ini your circadian cycle. 7. Increase the intensity of your exercise, but do it intermittently and target all the major muscles. 8. Move or exercise soon after meals to burn off the glucose spikes. 9. Cycle stress and cortisol by avoiding: - Chronic overwork - Excess exercise - Chronic negative emotions - Chronic infections. - Etc. 10. Integrating deep cleaning inside body by integrating long fasting every several months. 11. Addition: Self judgement and comparing to others don’t help apply the habits. Be kind, get focused, and LOVE YOUR SELF. 42 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 3 replies @DennisSmithGrandCayman @DennisSmithGrandCayman 7 days ago Hi Rimon, Past the age 75 mark this year and have no intention of coasting to the finish line. Your comprehensive training and lifestyle videos are excellent and well done. Thank you Reply @rudyhenderson5002 @rudyhenderson5002 4 months ago Thanks Rimon for the well-presented, useful and well-researched tips on preserving our health span. Your videos are always the most enjoyable to watch due to your great presentation. 3 Reply @aroonsarin8303 @aroonsarin8303 4 months ago I love that you can jump in the video just between the habits using the chapters. And you explained longevity for those who are new to the concept! Like myself :) 4 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @lindaallen2412 @lindaallen2412 3 months ago I hope your wife is improving everyday, stay strong sending energy and strength to both of you, I think it's amazing that you are finding time to do these videos at all❤❤ 2 Reply @jgs9911 @jgs9911 4 months ago Very informative. Long video but well segmented to allow you to watch at your own pace. Thank you 4 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @mckolabs5844 @mckolabs5844 1 month ago Nice presentation and good work by the researchers. Fact is, as “scientific” as this may sound, it is extremely complicated to figure out those “efficient thresholds”, which also at a deeper look vary individual by individual (based on their context, emotional and psychological state and context etc). And also very difficult to control through lifetime. When I think about the “presumed benefits” (assuming we are correct and perfect in the execution of the plan), we realize that it comes down to just a few years of “extra life” (maybe 5-7 if we are lucky). And that comes with excruciating detail management about diet, quantify and frequency of exercise and exercise type and other limitations and management guardrails..then I wonder...is that longevity worth it? We all decide for ourselves clearly, but personally I am not so sure... Reply @pjaworek6793 @pjaworek6793 3 months ago "God is not keen on longevity", that was funny. You are my savior Rimon! Great video, I was always worried I start losing muscle within a day or two of not intensely exercising. Thanks for the info about having about 2 weeks before major losses. Reply @michaeljozwiak25 @michaeljozwiak25 2 months ago This is a mind blowing channel. You are now one of my young YouTube fitness influencers ranging from 34 to 43 years-old. I am 66 years-old and here are some of my influencers: 1). Hippocrates- Time heals all wounds, heal thyself and walking is humankind’s best medicine. 2). Jack Lalanne, 3). Coach James Schwarzbach-my 9th grade, high school coach, 4). Dr. Kenneth Cooper-Walking is humankind’s best medicine. 5). My current primary care doctor since the year 2000. Reply @jamesdelia2711 @jamesdelia2711 3 months ago Great routines—you mention it’s impossible to live forever…it’s perhaps impossible right now but it may not be in the future 1 Reply 1 reply @itidings @itidings 3 months ago Great teaching. What if 64 and doing intensity as a woman, would that release more cortisol levels that cause you to gain weight? Reply @dagrawal03 @dagrawal03 3 months ago So, how often should someone perform high intensity exercise for reaping longevity benefits? I missed this in the video. Reply @planetmongocommoditiesexch9079 @planetmongocommoditiesexch9079 2 months ago Before demonizing carbohydrates, bear in mind that it's the high fat content of the Standard American Diet that causes the insulin resistance underlying excessive blood sugar spikes. Exercising after meals, or potato loading before an endurance workout, are great ideas. 1 Reply @SwastikaNohara @SwastikaNohara 3 weeks ago Need your opinion. Is it okay if I break my fast with fresh fruits? I’ve been fasting 18 hrs (6 PM - noon next day) and exercise 30 minutes in the morning, mostly strength training or HIIT, I drink enough water. Then I eat fruits first (apple, pineapple, dragon fruit, oranges, pear) when I break my fast. Then in 30-60 minutes I have lunch, mostly protein and veggies/salad/sautéed veggies. I’m 166 cm, 52 kg, normal weight. My aim is to get fit. What do you think? Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @paulcohen6727 @paulcohen6727 4 months ago Throughout history people have survived on complex carbs, thing like whole grains, tubers and squash to get the bulk of their calories. In fact the earth could not come close to supporting it's population of humans without complex carbs. But this is different from simple and refined carbs which are sugary treats and grains that are processed so they loose much of their fiber, that is white flour or rice. These produce a much more rapid spike in blood sugar. It's normal to have some increase in blood sugar after a meal no matter what you eat which is why we fast overnight before having our blood sugar tested. But sweets and refined foods spike it faster. It is also natural for humans to be active either hunting and gathering or doing agricultural activities. So we can eat meals of complex carbs and then do mild to moderate exercise without fear of damaging our health. A note on potatoes: hot potatoes do spike the blood sugar unlike most natural carb foods but if cooled overnight in the refrigerator, they form resistant starch complexes that don't spike the blood sugar to an unhealthy extent. Pasta is made of starch with a structure that is more resistant to digestion also, so eating moderate amounts of it are no problem. 10 Wellness Messiah with Rimon Reply @michaels3708 @michaels3708 4 months ago Could you explain how much or long etc fasting is needed to trigger autophagy, currently skipping breakfast, so 13 hour fasts... 11 hour window eating - thanks 3 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @paulcohen6727 @paulcohen6727 4 months ago Isn't autophagy global during fasting? Side-benefit of fasting: release of BDNF. 3 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @patrykstrach4469 @patrykstrach4469 4 months ago Frequently with Weight Training make sense, but what about Aerob/ Cardio Training such as Thai Boxing or Running? I don’t think it’s a good idea to do that just once a week. What do you think? 4 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 2 replies @fidahossain7604 @fidahossain7604 2 months ago Thanks a lot. Reply @JohnSmith-ms8nj @JohnSmith-ms8nj 4 months ago Nice presentation 2 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @pecent @pecent 2 months ago Exercising after meals is good for longgevity, but not eating before exercise is better. Not eating immediately after exercising ist the best? 1 Reply 1 reply @flac5897 @flac5897 3 months ago Nice video. My question is people 50 and older? They can’t do all hitt crazy Reply @TesseractPleiadesOrion @TesseractPleiadesOrion 2 months ago Yeah, definitely don't agree about exercising right after a large meal. Your body is busy digesting, it can't do too many things at once (at least mine can't LOL) 😄 In my case, I actually feel more sluggish and have sugar/energy crashes doing any intense activity straight after a meal. Eating 2-3 hours before exercise, and then possibly light simple carbs with electrolytes during it, and fat & protein afterwards (up to an hour later), works better IMHO. Reply @saithrinay2678 @saithrinay2678 4 months ago Can anyone help me achieve my goal how and where do I get a job on resarch of increasing human lifespan especially mine, my education is master of pharmacy in pharmacology in India country Bangalore city my goal is to find solution for mortality to become immortal please anyone help because I don't like to do other jobs Reply @Doriesep6622 @Doriesep6622 1 month ago Am I the only one annoyed by longggg introductions? Finally starts at 15:07. 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @hilaryford6493 @hilaryford6493 2 months ago Please drop the awfull distracting music! 1 Reply @antonstepanov5348 @antonstepanov5348 4 months ago Tov Meod 1 Wellness Messiah with Rimon Reply Wellness Messiah with Rimon · 1 reply @bflbflbfl @bflbflbfl 4 months ago 2nd 1 Reply @Bigman240 @Bigman240 2 months ago (edited) Honestly, what does a rich thirty-eight year old football/soccer player know about longevity? GO VEGAN, exercise, get enough sleep, and you'll be fine! 1 Reply