Autophagy 101 - Everything You Need to Know - with Dr. William Dunn

Autophagy 101 - Everything You Need to Know - with Dr. William Dunn Naomi Whittel 116K subscribers Subscribe 8.2K Share 400,223 views May 13, 2019 Want to learn more about the benefits of autophagy? Check out my blog! https://www.naomiwhittel.com/benefits... The Real Skinny on Fat is a 9-part documentary series that uncovers the truth about FAT and how it affects your health, your weight, and your aging. It is available to watch online for FREE beginning May 14, 2019 at 8PM EST. Be sure to sign up here to join us http://aff.therealskinnyonfat.com/aff... and receive your unique viewing link! Autophagy is a word we’ve been hearing a lot recently, and I have a strong feeling that this is just the beginning. On a recent trip to Tokyo I had the honor of interviewing Dr. Yoshinori Ohsumi, the very man who introduced autophagy to the world and won a Nobel Prize doing so in 2016! (You can find that interview here: • Rare Interview wi... ) Dr. Yoshinori Ohsumi spoke honestly and humbly about our limited understanding of the full potential autophagy has, claiming he believes we only understand about 30% of what it can actually do. That is an exciting prospect to consider, especially having come across some remarkable findings. Having the opportunity to talk to various individuals who are on the cutting edge is of course key in learning more and exploring this science. I find it extremely enlightening to learn from those who’ve grasped an understanding of what it can do for our health. Studying autophagy and its benefits for us is nothing short of a miracle, and something I want to share with all of you. In today’s video, taken from our 9-part docuseries “The Real Skinny on Fat,” I talk to Dr. William Dunn, PhD, a professor of anatomy and cell biology at the University of Florida and one of the most respected authorities on autophagy. He has been studying the process for more than thirty years. His insight is truly fascinating and worth watching to begin to understand the science and benefits of autophagy and how you can activate it. I hope you enjoy the interview excerpt and please be sure to post your comments and questions below. This is definitely going to be a subject we will be devoting a lot of time to, so expect to see more videos on this channel. If you haven’t already, I highly recommend subscribing and hitting the little bell button to get notified as we are posting three videos a week on subjects related to health, wellness, and exploration. You can find them all here: Mark Sisson: • Amazing Keto & Fa... Ben Greenfield: • Amazing Health & ... Thomas DeLauer: • Amazing Keto + Fa... Drew Manning: • Drew Manning - Dr... Dr. Amy Killen: • Essential Health ... To your health and happiness :) -Naomi _______________________ My Mission Our health and wellness is our most precious possession. My goal is to help you not just survive but thrive by optimizing our vitality through functional foods, through nutrients, through movement (exercise), through beauty and through self-care. I’ve always considered myself a guide, an explorer, a discoverer who isn’t content with simply being told that things are the way they are. It’s this insatiable curiosity that leads me to travel, to touch and experience for myself, and see with my own eyes, to draw information and learnings from cultures all over our globe in order to share them with you so that we can all live a better life. Join me on this journey and allow me to guide you to your better life today. ____________________________________________ Be sure to hit subscribe to get notified about upcoming content. We will be uploading at least 3 videos every week on themes related to nutrition, beauty, exercise, wellness and self care, functional foods and nutrients, travel and learning about how different cultures eat and discovering the secrets of longevity. We’ll be uploading how to’s, tips and lists, recipes, live Q&A’s, travel videos, and lots of exciting (and educational content). We will be going off the beaten path in search of new and exciting ideas to help you enjoy a more vibrant and fulfilling life, and a better you. So join me in this adventure. Subscribe, leave feedback and comments, if you like the video hit the like button, your feedback is very important to me. For more info, and to learn more about what products I have on offer, and to learn more about what we do, read blogs, find new and exciting recipes and SO much more, be sure to visit my website at… https://www.naomiwhittel.com/ Facebook: https://www.facebook.com/NaomiWhittel/ Instagram: https://www.instagram.com/naomiwhitte... Twitter: https://twitter.com/naomiwhittel?lang=en Amazon: https://www.amazon.com/Naomi-Whittel/... Key moments View all Naomi Whittel 116K subscribers Videos About 652 Comments rongmaw lin Add a comment... @samhemmati1704 @samhemmati1704 7 months ago I’m 59. My wife and I started IF two years ago. To begin with, it was pretty tough as I was basically a sugar junky! I persevered and gradually got to 18/20hrs fasting. Two years on, I lost 18kg/3.5stones and IF has become a life style. I run 8.5k 5 days a week on empty stomach and I’m faster and more agile than before started IF. We both have bags of energy and plenty of focus that never thought I possessed! For my 60th birthday in March, I’m planning 10k run every day in March followed by a marathon at the end of the month. We now do a 48hrs fasting the last weekend of every month to maximise autophagy. IF has been a game changer for quality of life and longevity. 44 Reply 2 replies @c8Lorraine1 @c8Lorraine1 1 year ago I began fasting at 8 hours and then increased by one hour each day, with only the occasional slip . Now I’m at 18 hours with a 6 hour eating window. I’m working towards 36 hours fast. I feel fantastic 32 Reply @feconway5180 @feconway5180 1 year ago (edited) 6/29/21 my autophagy & cell cleaning occurred at “20hr fasting -4hr eating window” I’m a graduate of “16-8” In 2019 & dropped 18Lbs. Today Since doing longer fasts Or 1 meal a day, Within 3 days the redness in my face vanished by doing “20-4” Amazed😊. 25 Reply @edwardcoyle5425 @edwardcoyle5425 3 years ago At 57, I was fit and about 220lbs, athletic. But, I was feeling old. Previously I rarely ate breakfast when I started IF. Doing IF I immediately began to feel better. Im terrible at fasting and often cheat in the afternoon. Occassionally, I will fast all day. The improvements I have noticed are numerous. Skin, memory, joints , attitude. I feel decades younger. I recommend to all. 184 Reply 3 replies @HawaiianLimey @HawaiianLimey 3 years ago I started prolonged fasting early in the year and it has made the single most significant difference to my health out of all my practices. 74 Reply @peterstock1327 @peterstock1327 2 years ago Currently doing OMAD and loving it for the last 12 months. Just finished a 7 day fast which really helped my chronic shoulder pain which I thought may need surgery. Will go 10 days soon - love intermittent fasting - great video thanks. 46 Reply 3 replies @sherrieloyd4572 @sherrieloyd4572 2 years ago I’ve been fasting now for 18 hrs a day and it has really helped me feel better with my keto plan.. was surprised about not being hungry.. 43 Reply 2 replies @adelferoz4168 @adelferoz4168 2 months ago The best analogy is just imagine that grocery stores are all closed for a month. What would you do. First you would finish off all the food in your refrigerator. Then you would start eating all the leftover foods, thereby clearing your fridge and house of all the old and outdated food. This way you have exhausted your old and stale food. Now your house is ready for fresh food to come in. That is the best layman's analogy. 5 Reply @williamr3766 @williamr3766 2 years ago Just beginning the IF process. Trying to learn as much as possible about the benefits and risks. This was an excellent interview of a highly credentialled doctor that has committed 30+ years to the study of Autophagy at the cellular level. Thank you, sir. 2 Reply @Radnally @Radnally 4 years ago Eating all the time is so psychologically programmed into most of us. I found that doing fasting, for me, was 99% changing a habit. 461 Naomi Whittel Reply 26 replies @suzum5689 @suzum5689 3 years ago Love that he wants to find solutions to help bone cancer in children. That says a lot about his heart. :) 97 Reply 3 replies @lamnuck @lamnuck 4 years ago I've been doing IF for 8 months and feel like I discovered a fountain of youth ! 217 Reply Naomi Whittel · 16 replies @benilynko6437 @benilynko6437 2 years ago I did 2 months intermittent fasting before I turn 60 yrs old. I did really look young and had intensity energy. I work 15 hrs throw the day every single day. I feel really good never get tired and hungry. I still doing it till now and I will keep for ever. It helps me so much fir being working so hard the whole day. I'm constantly working the whole day 15 hrs everyday. 7 Reply 1 reply @richzerby9238 @richzerby9238 2 years ago I happen to work at Penn State, so that was kind of neat hearing that the Dr. started his journey there. I have been using a keto diet and IF to control my type 2 diabetes now for around a year. I have lost 22 pounds, back to my proper weight, and have been able to stop using all medications to control my diabetes. It really did not take long at all to get used to fasting, I don't find myself getting hungry ever. I am just starting to research how autophagy works and how I may benefit from it. Thanks so much for the informative video. 3 Reply @ttocselbag5054 @ttocselbag5054 3 years ago (edited) Thank you Naomi for this very enlightening interview with Dr Dunn. Autophagy fascinates me. Well done. 15 Reply @glynch71 @glynch71 9 days ago Great interview Miss Whittel. I'm wondering if Autophagy is helpful in PREVENTING diseases? I think it would be, since the cells are cleaning themselves. It's fascinating and a little counter intuitive that you want Autophagy at times and you don't want it at others. Great stuff. Reply @timogronroos4642 @timogronroos4642 3 years ago (edited) I've been intermittent fasting for two months now and I don't find myself hungry when I wake up. I don't feel the hunger I used to have at all. My body has adapted to change quickly between burning glucose and fat, so my body doesn't need to remind me of eating often. This is one of the best reasons to have IF as eating pattern. I was just moderately overweight 52 Years/176cm/79,5kg and now I'm 73,5kg and feeling great mentally and physically. IF triggered growth hormone put me into lifting weights and IF is giving me feedback which foods are better for me, so I'm in a positive loop because of IF. I'm feeling (and looking) like 40 Years old again. 14 Naomi Whittel Reply @LandE520 @LandE520 3 years ago Just found your channel. Love the videos. I appreciate your efforts and research on Autophagy. Thank you !! 19 Naomi Whittel Reply Naomi Whittel · 1 reply @reetta8398 @reetta8398 3 years ago I've never been hungry during the morning. Now I'm doing omad and I do feel it is so easy for me. First month was kind of hard, but now I am so used to it I barely even get hungry anymore. It's more of a mental battel cause I was used to eating so often 75 Reply 3 replies @michaelngan99 @michaelngan99 1 month ago Excellent interview. I love your insightful questions. And wise answers from an Expert. Reply @robertdemarais3327 @robertdemarais3327 4 years ago Great video! I feel really good while fasting so it's probably the autophagy kicking in. 27 Naomi Whittel Reply @bunjicarlin1 @bunjicarlin1 2 months ago (edited) I started fasting for weight loss and to find and adapt a new life-long way of eating. Once I reached my desired weight, I now fast for Autophagy 20 hours each day and one 36 hour fast starting every Sunday evening 1 Reply @mctourer5549 @mctourer5549 3 years ago I think the gateway to Enjoy fasting is by eating a Ketogenic life style. Hunger is suppressed and you stay satiated so 1 meal a day is really easy to achieve and when you want to fast for longer periods your body is more adjusted to it. Great topic! 6 Reply 3 replies @lizardfirefighter110 @lizardfirefighter110 3 years ago (edited) OK, here is my two-cents: Today I fasted for 18 hours. I have done a total of 20 pull ups. At the end of the fast, and in of a twenty minute period, I did 150 jumping-jacks, 100 push-ups and 100 squats. I then drank a tonic of ice water, turmeric powder, matcha powder, ginger powder, cinnamon powder, stevia liquid and a tablespoon of apple cider vinegar. This was followed with a huge salad and 4 soft boiled eggs. Multiple cups of tea all day, either Matcha or Dandelion Root. Had some Milk Thistle with one of those cups of tea. During the eating window I snacked on 7 handfuls of Pecan nuts and two Brazil nuts. For dinner I had chicken soup with finally chopped broccoli as a topping. For dessert Lily’s chocolate. Later I will take vitamin supplements Zinc, Magnesium, Potassium, D3, K2, B-Complex, and C. Next is 8 hours of sleep. Well, 4 years ago I started my life style change when I was diagnosed with Atrial Fibrillation. I am 65 and my doctor is unable to detect Atrial Fibrillation. In closing, eat well rest well, keep hydrated, exercise moderately. Real food is medicine. The tools to optimize your health are HIIT, IF, cold showers, saunas, red light exposure, and meditation ( controlled breathing) Well there you have it, the things that are working for me. 137 Reply 9 replies @patdear80 @patdear80 2 years ago It's amazing the creation of the human body & its capability to recover & restore, we are only studying the surface of medical knowledge, well done to all the research, it will help a lit of people 😊 4 Reply @sutats @sutats 1 year ago Great discussion. Very informative and clear. 5 Reply @juliolutterbach1820 @juliolutterbach1820 2 years ago Great interview! Thank you so very much to both of you 1 Reply @fishermgcj @fishermgcj 5 months ago 5 1/2 OMAD now and love it, love it, love it. A few pounds gone but better is the healing taking place and more energy and feeling of well-being! Reply @Thecasinocrashers @Thecasinocrashers 3 years ago I’ve fasted most days of my life at least until 4:00 pm for years, as a religious practice. I feel much better when I eat once a day and later in the day. I do this most days, but certain days when I want to eat with my family, I eat however I want. I am 60 and I feel great. 12 Reply 3 replies @ponysmoke7884 @ponysmoke7884 2 years ago Just completed a three night two day water fast. I’m also on Michael Mosley’s Fast 800 diet, but doing all my eating in an 8 hour window. I feel fantastic. Lost 3kg in a week. Feel like I’ve discovered a new way of living. 2 Reply @lexandratsimpidi4803 @lexandratsimpidi4803 2 years ago Great information.It's time to change our eating habits and don't listen to food companies who want us to eat all day long! 2 Naomi Whittel Reply Naomi Whittel · 1 reply @mikekenney8362 @mikekenney8362 1 year ago Quincy Jones opined “We’re saving our own lives” This is why scientists must be free to explore a Great Blue Sea, without political or economic priorities. Early Cancer research blossoms into a profound perspective of the process of life. Dr Dunn is “Knock-knocking on Heavens Door” of metaphysics. Bravo 1 Reply @williamjeffreys2980 @williamjeffreys2980 2 years ago To your discussion at the 9:00 minute mark, the more consistently you fast, the easier the transition period becomes. It may take months, but eventually your body will adapt. I can feel the changeover now when my body switches to other sources of fuel, and it only lasts literally a minute or so. The other thing that takes a long time, but eventually you'll adapt is to be active while fasting. I have been doing it long enough now that I can engage in vigorous physical activity while fasting and still have plenty of energy. This was not the case early on. 3 Reply @kysweetheart1964 @kysweetheart1964 3 years ago thanks very informative. I knew there was and on/off benefit with cancer, but was curious of the mechanism of when to be "on" or "off"; and the benefit of each, you helped to answer, thanks Dr Dunn and Naomi. Subscribed, first video interview I have viewed of yours. 2 Reply @sajanpatel7285 @sajanpatel7285 2 years ago I did 35 day fast and another 28 days. Never felt better in my life. I felt 20 years younger no joke. 51 Reply 54 replies @scottbarrett1763 @scottbarrett1763 2 years ago Love your autophagy videos! Thank you! Reply @Rosie_Apple_Delight @Rosie_Apple_Delight 2 years ago As someone who is only 45 but dealing with Early Onset Parkinson’s, hearing “aging is just going to happen” is very disappointing doctor. I am seeking out any way possible to protect my brain, seeking out how to induce atophogy so that I can protect my brain and be there for my kids. 9 Reply 5 replies @RocksteadyRuth @RocksteadyRuth 4 years ago Love everything I have learned about autophagy with Naomi. I don’t know how old she is, but she looks amazing , glowing skin, glossy hair, beautiful figure and the warmest, genuine smile......plus she makes listening easy, as do all her interviewees I have seen to date. 🙏✨ 12 Naomi Whittel Reply 3 replies @littlevoice_11 @littlevoice_11 4 years ago Can you trigger autophagy through 18:6 if during the feeding window you are eating to gain weight (ideally lean muscle) as part of weight restoration in recovery from illness? Or does weight gain in many form prevent autophagy and it's anti aging effects? Reply 1 reply @valeriabroadnax6628 @valeriabroadnax6628 3 years ago Day 2 of fasting! Praise God for the power of fasting! 201 Reply Naomi Whittel · 11 replies @manuelojeda9144 @manuelojeda9144 2 years ago It's fascinating. I enjoyed the discussion about Autophagy. Bravo! Reply @Andrewyn @Andrewyn 3 years ago Years ago I did a 5 day water fast without doing low carb first. It was so incredibly painful and I couldn't focus on anything because of extreme hunger. My entire body ached especially my lower back which I had injured a few years before. I'm trying intermittent fasting now to make it less painful and becasue I take supplements every day. Would going low carb help with the pain? 3 Reply 10 replies @markellis6898 @markellis6898 3 years ago (edited) Hmm, I do an alternate day fast and am not, at all, "starving when I wake up." I assume because I have a fat-burning metabolism and am on a ketogenic diet. The human organism has spent a lot more time going hungry between meals than it has spent having 3 meals a day. Overall, I enjoyed the interview Naomi. 5 Reply Naomi Whittel · 1 reply @theriac. @theriac. 4 years ago You would think Dr Dunn was just about to serve you with your groceries. What a humble (and great) man 37 Naomi Whittel Reply Naomi Whittel · 3 replies @millirewo5249 @millirewo5249 2 years ago (edited) I like these series about autophagy and english subtitles.Tell me more about the relation of autophagy and cancers or other diseases,please. Reply Naomi Whittel · 1 reply @ChristianeMarshall @ChristianeMarshall 3 years ago Thank you. I have a question. I was under the impression that cancer cells would not survive fasting because they don’t do autophagy. So does intermittent fasting not help with cancer? 2 Reply 7 replies @zeek4749 @zeek4749 4 years ago (edited) I eat once a day and it feels amazing 😀😀😀 thank you for all this information beautiful lady . The doctor is smart and love the guy 😍😍😍 cancer has hit my family three times and I hate the word and it needs to die 😢😢😢 62 Naomi Whittel Reply Naomi Whittel · 2 replies @francorui2493 @francorui2493 2 years ago More videos please, unbelievable information Reply @busratz @busratz 3 years ago i started IF two months ago, i lost 11+kgs, my skin improved, my nails and hair grew fast and stronger, my heartburn gone, felt amazing and most importantly i reversed my insulin resistance. so much healthier/better focus during the day. I gradually started, firstly i fasted for 18 hours, then 20, then i do OMAD- 23 hours fasting and 1 hours feasting. My gut problems gone&i didnt experience hunger. I drank bulletproof coffee with some good coconut oil and drank 1tbsp apple cider vinegar when i get up/and while i'm eating. I quit sugar and went low-carb, i tried to get into ketosis but i don't know if i achieved it or not. i stopped doing IF suddenly after losing 11kgs, just for experimenting, curious about what will happen. I introduce sugar and carbs back to my diet -in moderation, instantly i suffered gut problems, poor digestion, dry skin and pretty bad breakouts. so, i'm back with the OMAD diet, i'm feeling awesome, my problems are no longer here and still continue to loose weight. Highly recommented. 🤚🏻 8 Reply 3 replies @robertdavis5714 @robertdavis5714 3 years ago That is exactly what happens, wake-up and am quite the bad mood but like you said come 9am everything is ok. Reply @robinluich5576 @robinluich5576 3 years ago I just did a 4 day fast and now on keto. Ive done keto on and off for 20 years. 6 Reply 1 reply @KeePractising @KeePractising 3 years ago For decades I've read about detoxing with conventionals saying it's fantasy. The body does that anyway all the time. Yet no doubt about the curative value of fasting etc. Looks like the answer lies in autophagy increasing massively with fasting etc. Must happen in normal circumstances too surely and to some degree. 1 Naomi Whittel Reply 1 reply @tommymonroe8706 @tommymonroe8706 1 year ago I’ve upgraded to just one meal a day with very little hunger. It takes a while to get used to. Trying to reverse a fatty liver. 1 Reply @vigneshkrishpt9452 @vigneshkrishpt9452 2 months ago So... is there a magic number that autophagy kicks in after 'x' hours of fasting? And how do we know that 'autophagy' is activated? And ... Is it possible to measure/quantify autophagy? Thanks. Reply @KetoMama777 @KetoMama777 4 years ago I love all the information i can get. Thank you much! 11 Naomi Whittel Reply Naomi Whittel · 2 replies @kennybrooks8374 @kennybrooks8374 4 years ago What are the stipulations to get and be in autophagy? How long does it take to get into autophagy? 2 Reply 2 replies @infiniteg7852 @infiniteg7852 2 years ago I would like to try IF. Maybe a 16/8, but I would like to maintain all the weight that I’ve gained and/or Gain more while doing it. Is it possible? Reply @GmoBuelna @GmoBuelna 3 years ago (edited) Wow, amazing videos, I enjoy so much, and learn so much too, watching your profesional work, thanks a lot 1 Reply @TheNYgolfer @TheNYgolfer 3 years ago Just watched a video on autophagy by Dr. Fung. He says it takes 24 to 48 hours of fasting for autophagy to kick in and that as soon as you consume protein, autophagy is turned off. If this is true then the only way to get any benefits from autophagy is to water fast for several days just to activate autophagy and then eat no protein in order to keep from turning autophagy off. My question, how many days of autophagy do you need to see benefits if you are doing it for general health purposes ? How often should you do it for those purposes? 8 Reply 14 replies @ChrisGaultHealthyLiving @ChrisGaultHealthyLiving 4 years ago Thanks for the informative video. 4 Naomi Whittel Reply @sets-reps @sets-reps 3 years ago Most EXCELLENT video! Thank you Dr Dunn! Thank you Naomi Whittel! 👏👏👏🤗 4 Reply @matthewmaneri3098 @matthewmaneri3098 3 years ago The cell eats parts of itself, the damaged parts? Won't we eventually be left with shrinking organs with the cells that don't divide.. like the heart? What's the benefit in getting rid of damaged mitochondria and organelles of the heart? What affect does that have on the organ? Are we just assuming it makes it healthier or does it actually? 2 Reply 4 replies @gabrielr8642 @gabrielr8642 5 months ago Dr. Dunn is so sweet!! hes right autophagy - its not about anti aging but aging healthily & gracefully might I add. Reply @fiete9859 @fiete9859 1 year ago She looks to excited and genuinely deeply fascinated in this, love the energy. Reply @Shelbymaldita @Shelbymaldita 11 months ago I tried fasting until after 2pm I usually have meeting at noon once a week I noticed that my blood sugar drops and I forget words when giving report so I eat an egg at least in the morning. Reply @LizandSkatz @LizandSkatz 2 years ago We love fasting for autophagy. Lost 80lbs so far 💕💕💕↖️ 16 Reply 2 replies @myyoutubepassion573 @myyoutubepassion573 2 years ago Could fasting help with a scalp infection caused by a fungus?Could that help the immune system kill the fungus? 2 Reply 2 replies @lyhuynh7537 @lyhuynh7537 1 year ago She’s so stunning that it’s hard to focus on the information, but love the information and interview and so I subscribed! 3 Reply @teemothykorneliusmosac8648 @teemothykorneliusmosac8648 1 year ago Would a Vitamin supplement or NAD+, or drugs such as metphormin or testosterone can break the fast and cancel autophagy? Reply @Soul.Is.Willing @Soul.Is.Willing 1 month ago Should we supplement during prolonged fast? I'm day 7 of 40 day water fast. Will autophagy go on for entire fast? 1 Reply 1 reply @kristianmarc1024 @kristianmarc1024 1 year ago Hi Naomi, when Dr. Dunn said the kidneys are very active in Autophagy, does it mean that Kidneys do repair themselves? Which contradicts old belief that Kidneys does not have the ability to repair itself. Reply @mickmoriarty7780 @mickmoriarty7780 2 years ago Great video, thanks. If he's waking up starving, he's eating the wrong food. 3 Reply @ViniBsb1973 @ViniBsb1973 4 years ago This video should get milions of views and likes. Subscribing now. Thanks for your job. 10 Naomi Whittel Reply 1 reply @bitburg40 @bitburg40 8 days ago I’m really hoping that functional medicine will have the same effect on big pharma and mainstream medicine as independent journalism is having on mainstream media. 😁 1 Reply @wordpressobsessed9067 @wordpressobsessed9067 3 years ago Autophagy is great, but fasting to induce autophagy will never be taught in the mainstream. Way too much money in food and cancer treatment. 368 Reply 28 replies @valeriejohnson2367 @valeriejohnson2367 4 years ago I am soooo grateful for my friend who just told me about you........I am learning so much, and started Glow 15 3 Naomi Whittel Reply Naomi Whittel · 2 replies @sylviaking8866 @sylviaking8866 3 years ago if one is fat adapted fasting becomes very easy. Your body very happily will utilize your body fat for fuel. If you are a sugar/carb dependent for energy you may have a awful time adapting to fasting. 4 Reply 1 reply @SusanaXpeace2u @SusanaXpeace2u 2 years ago So at what stage would a tumour be before it would turn on autophagy for its own benefit? So many people fasting, but are they all certain they don't have a new tumour? This interview doesn't answer that uncertainty. 8 Reply @LTPottenger @LTPottenger 2 years ago You can't turn a tumor cell's autophagy on or off through fasting, the cell itself regulates it and does what it wants to do. 1 Reply 1 reply @ObesityisNotMe @ObesityisNotMe 3 years ago Fasting is a blessing 65 Reply 2 replies @lolad407 @lolad407 2 months ago Question - if someone is practicing an IF lifestyle and triggering autophagy and unknown to them have cancerous cells in their body, are those cancer cells going to grow and spread faster than they would normaly? Reply 1 reply @Rackad @Rackad 2 years ago Problem is that u need between 48-72 hs of fasting to get the benefits that this guy is talking about. If you are on ketos it could be reached already after 24hs. I like IF, but I'm not going to 48hs without food Reply @marytaylor2381 @marytaylor2381 2 years ago Never hungry in the morning especially if I eat the proper foods when Intermittent fasting 2 Reply @crosseyed45 @crosseyed45 2 years ago An interesting question would be based on his his comment about Autophagy protecting the cancer cells. If a person doing Chemo should avoid autophagy? 1 Reply @mustafabaris9681 @mustafabaris9681 2 years ago (edited) The best video I’ve seen on YouTube..! Thanks a million ..! 3 Reply @ksveness @ksveness 2 months ago Hi. I'm 65 and have stage 4 metastatic prostate cancer with significant metastasis in my bones. I recently finished a 21 day water fast and now try to keep up a ketogenic diet and practice intermittent fasting. I'm a bit confused from your presentation, should I not be pursuing autophagy? Reply 2 replies @erwinrogers9470 @erwinrogers9470 10 months ago Love it 🔥 Reply @klabruyere5037 @klabruyere5037 2 years ago Dr. Dunn, I see so many graphics on the benefits of fasting and how autophagy prevents cancer. Can you comment on this? Reply @avv1517 @avv1517 4 years ago Thanks. It would have been helpful to clarify why/ when Autophagy should be turned off. When does Autophagy aggravate disease.... 18 Reply 1 reply @amyr3285 @amyr3285 3 years ago Dr. Jason Fung of Toronto, CA has been doing studies on fasting and autophagy since 2010. 91 Reply 3 replies @goranvuletic8873 @goranvuletic8873 1 year ago If you are on a low carb diet, you don't need to be engaged in anything, you are simply not hungry. I call this freedom! Life's good. Reply @jamesrankin9833 @jamesrankin9833 2 years ago Good stuff! Reply @lindalentz5093 @lindalentz5093 3 years ago (edited) Turn on autophagy for aging. Shut down autophagy before blood supply gets to tumor. Autophagy helps the heart, liver any organs or any cells not dividing, kidney most active and helped. Needs to be studied 25 Reply 2 replies @lorimeruena8926 @lorimeruena8926 2 years ago I want to ask if not eating from 9pm to 9am could be considered as fasting and you do it everyday, is that ok? Reply 2 replies @Galatzo @Galatzo 1 year ago I'm on my second hour of fasting Lol, let's go! 1 Reply @nuglifeproductions5994 @nuglifeproductions5994 2 years ago Does drinking anything other than water during a fast ruin autophagy? Teas, Salt water, lemon water? 1 Reply 1 reply @Boboshempy @Boboshempy 4 years ago How are you and Dr. Dunn measuring that you are activating autophagy through intermittent fasting? 10 Reply 4 replies @americanbullysvlog2069 @americanbullysvlog2069 10 months ago I fast 20 hour and i got a 4 hour eat window but i do take carbohydrates not to much but still im losing weight ! :D but do i have Autophagy even when i eat a few carbohydrates ? Reply @coalknob @coalknob 3 years ago Interesting subject, and she's a really good interviewer. 1 Reply 1 reply @johnbrennan3615 @johnbrennan3615 2 years ago Fantastic video 😃 Reply @MrSharkster59 @MrSharkster59 1 year ago Sounds as if fasting and autophagy will also clear or at least reduce artery clogging throughout the body and around the heart. Reply @pablopolski1228 @pablopolski1228 3 years ago He is very interesting but he said one thing that is concerning. If you have cancer you want autophagy turned off to decrease the possibility of metastasis. Most people will not know if they they have a cancer until it is well advance. As a result following this recommendation could hasten your demise in early cancers. Reply 1 reply @brendamaclean4440 @brendamaclean4440 2 years ago Listen Dr Jason Fung!! OMAD, no flour, no sugar, high healthy fats, low carbs( from only veggies), low- moderate protein 6oz . 48 hour fasts on weekends. I feel so much healthier and younger than I did 2 mths ago. A new life not a diet. 2 Reply @Mmyers1177 @Mmyers1177 2 years ago (edited) ATP = Adenosine Triphosphate. Part of three energy systems our bodies run on. ATP gives up only one of three phosphates to create instant energy for muscles. Wiki it very interesting read.... Reply @bobcocampo @bobcocampo 1 year ago How is Autophagy working in the kidney? Can Autophagy Reverse Kidney Desease? Reply @tigerfish9078 @tigerfish9078 2 years ago His conclusions relative to autophagy and cancer cell growth are the exact opposite of Dr. Valter Longo, Phd out of USC. Dr Longo has an entire program using fasting associated autophagy to reduce cancer development. 6 Reply 2 replies @martinsinclair177 @martinsinclair177 3 years ago My understanding is autophagy doesn't begin until 48 hours into fast 2 Reply 3 replies @mermer58 @mermer58 3 years ago I was thin in my youth because I employed IF and knew nothing about the benefits, that's just the way I ate. 36 Reply 3 replies @ugrozenavrsta @ugrozenavrsta 3 months ago So basically, autophagy is "self-renewal" , so to speak, of any type of cells including cancer cells. 1 Reply 2 replies @podcastbard @podcastbard 11 months ago Fasting helps with diabetes. I drink water to get passed hunger pains. Reply @sarahjustkidding @sarahjustkidding 4 years ago I've been trying to figure out the nuances of her accent while watching her videos. Just curious. Does anyone definitively know about where she grew up? Parental influences? It could also be an intentional form that was later learned. ...Again, just curiosity while actually here for the science discussions. 1 Reply 1 reply @SML54321 @SML54321 2 years ago Class 101 isn’t too helpful for non- scientist- just my opinion, but haven’t heard the complete video yet. Reply @katherinedownover7927 @katherinedownover7927 3 years ago Once you have cancer it's getting to late (not impossible )you need to clean your house everyday not once when it becomes a huge mess. 13 Reply 4 replies @louarmstrong6128 @louarmstrong6128 3 months ago Why doesn't he discuss ivermectin and fenben in regards to autophagy Reply @mandrinavaratne179 @mandrinavaratne179 3 years ago For me when i fast i get gastritis,does autophagy depends on age? 3 Reply 3 replies @Aaronchoi88 @Aaronchoi88 2 years ago i thought to reach autophagy you will need to fast for at least 36 hours, so how can you reach it with IF 18/6, 20/4 or even omad? 4 Reply 1 reply @hayuhinaira @hayuhinaira 3 years ago very interesting, I didn't know that autophagy is not always beneficial, as far as it concerns to cells dividing process, wow 2 Reply 1 reply @abhishekshah11 @abhishekshah11 3 years ago autophagy+lysosomal degradation is the whole equation. Please take care of your lysosomes too 1 Reply @rjrnj1 @rjrnj1 2 years ago Obviously he's not talking about keto lifestyle when he says how starving he is when he wakes up in the morning! Reply @paulklemer @paulklemer 1 year ago Does anyone know what I should eat to break a 5 day fast? Reply @mmdfitnessdudley5138 @mmdfitnessdudley5138 3 years ago Beautiful Reply @waffle_chair9269 @waffle_chair9269 2 weeks ago So many experts on health, with no hair? It’s so curious. Reply @jkabee @jkabee 1 year ago People aren’t addicted to food. People have become addicted to the additives in their food. 1 Reply @10sheeko @10sheeko 3 years ago Great topic but I couldn't help to notice how beautiful and straight this lady's teeth are! I'm jealous lol 12 Reply 3 replies @susydyson1750 @susydyson1750 2 years ago i recall a girl who did excess exercise and reduced the food intake the packmen started eating her muscle! Reply @pocopico7409 @pocopico7409 2 years ago I do wish all these doctors that discuss autophagy would give us a thumbs down or a thumbs up to it if you don’t know for sure if you have cancer cells in your body. It seems like it would be very dangerous to go into autophagy if you even think you might have cancer cells in your body. Since most of us will never know that, it seems like it should be avoided altogether. Think how many people watching these videos might decide they want to turn on autophagy to renew their cells in order to improve their body and their health, but might be harmed from doing it. And they have no idea that they are potentially endangering themselves because the dangers of autophagy are really never discussed on these videos. Something needs to be done about that. 1 Reply @shottyshot @shottyshot 11 months ago We need a new interviewer Reply @milenazeledon4350 @milenazeledon4350 3 years ago Dr. Dunn what can you tell me about bone density and 24 hours autophagy. Once they start deteriorating due to age. 1 Reply 1 reply @vinodpanwar7567 @vinodpanwar7567 3 weeks ago You all learn everything from INDIA 🇮🇳 Reply @JoaoLuissonhar @JoaoLuissonhar 4 years ago Excelent Thanks for sharing 5 Naomi Whittel Reply Naomi Whittel · 1 reply @emcarver8983 @emcarver8983 4 months ago (edited) I'm sorry to disagree, but this guy is making out that someone discovered autophagy in recent times. I was taught, as a student nurse, in the 60's about autophagy. I leaned about it in my biology o levels. There's is absolutely nothing new about this. While I love the work that has been done on it, and appreciate ways to boost it, It. Is. Not. New. Knowledge. It has been understood for thousands of years. No need to gild the lily. 1 Reply @ZeusHelios @ZeusHelios 2 years ago (edited) If Dr Williams practices autophagy then I wouldn't say he looks any younger for his age. Reply @troyrodgers9790 @troyrodgers9790 2 years ago seems like my whole body is in autophagy right now bcuz my body is eating itself 😩 Reply @taniagarcia8296 @taniagarcia8296 2 years ago Is it ok to start eating at 10 am and finish the eating window at 6 pm? Fast the rest of the time 1 Reply Naomi Whittel · 1 reply @MrMozzo @MrMozzo 3 years ago (edited) Soon as i wake up i down a half litre bottle of water which instantly smashes the hunger. Then im away🤘🏻💪🏻 20:4 2 Reply 2 replies @planetaryPoem9 @planetaryPoem9 2 months ago Did he say that in relation to cancer cells, autophagy allows them to grow, i.e. protects them? Reply @MMC-jp1gl @MMC-jp1gl 1 year ago I heard from another source that fasting applied during chemo helps protect healthy cells...this video says it would help cancer cells? God bless~ 1 Reply @Bigirondoug @Bigirondoug 1 year ago Not really everything you need to know. How long before autophagy starts ? how long does it last ? 1 Reply @ainsleyameerali7622 @ainsleyameerali7622 2 years ago Question .. when we begin our autophagy " fast" can we drink our water ? Reply 1 reply @ravig1740 @ravig1740 2 years ago (edited) Naomi Whittel your voice is beautiful. warm regards 🙏 God bless you you are a blessed gifted person Thanks 2 Reply @thilakavathysudharsan8591 @thilakavathysudharsan8591 2 months ago Does it help in agressive ovarian cancer. Already week tired and lost weight because of chemos surgery and disease... Reply @Sayiam @Sayiam 2 years ago Just to be clear, is he saying that autophagy should be turned off to fight cancer? 1 Reply @derekkeys6274 @derekkeys6274 2 months ago Is it me but he needs to be fasting😊 Reply @amysnews6808 @amysnews6808 2 years ago Maybe I'm just really stupid but is he saying IF is good or bad to prevent cancer? Really just good or bad overall? But particularly good or bad to prevent cancer bc cancer is very prevalent in my family so I want to do whatever I can to help prevent it whether that's a lot of fasting or eating every 2 hours. Reply @torptjejen @torptjejen 3 years ago Can one know if medication during a fast turns off autophagy? 3 Reply 1 reply @troyrodgers9790 @troyrodgers9790 2 years ago can fast/autophagy help with spinal conditions? Reply 7 replies @Doggo737 @Doggo737 3 years ago So what he’s saying is autophagy helps protect cancer cells and tumours. So all these nutritionists telling us it’s good are giving us misinformation because if we have got cancer cells in the body or a small rumour starting and we switch on autophagy we are helping it grow and protecting it???? 1 Reply 1 reply @semorado @semorado 2 months ago Our cells are just waiting for you to take a food break, so they can do their job instead of moving out! Reply @graceyinz @graceyinz 3 years ago It’s so confusing that he said “turning off autophagy for cancer. There are so many info on YouTube or google saying fasting especially long fasting is good for cancer patients even can cure cancer. 38 Reply 14 replies @Byrod1 @Byrod1 3 years ago William Dunn working on autophagy for 30 years but Nobel went to Japan. 6 Reply @alen1179 @alen1179 4 years ago I eat one meal a day in the morning. One hour eating window and then dry fast till the next day. 11 Reply 5 replies @fluffgirl1000 @fluffgirl1000 3 years ago That was great I learn something 2 Reply @SXLLXNBXE @SXLLXNBXE 1 year ago eating only every other or every third day. body likes it soooo much. Reply @podcastbard @podcastbard 11 months ago If we could age healthier, individuals medical cost could go down, but does the medical field actually want to make us healthy because there's no money in healthy people in the medical field. Reply @mash8619 @mash8619 4 years ago MANY THANKS 2 Naomi Whittel Reply @InSync3912 @InSync3912 3 years ago Naomi, did he mention how long he normally fasts for heart benefits? 1 Reply @Sawmine9 @Sawmine9 2 years ago This guy is smart but it is hard to watch him speak with a missing lower tooth. Hopefully he'll have that taken care of with all of the dental advancements today. Reply 2 replies @wisconsinfarmer4742 @wisconsinfarmer4742 3 years ago Tipping point, Mortimer's discovery that it is recycling. Reply @amandaspaintinglessons9908 @amandaspaintinglessons9908 3 years ago I've been pronouncing it Auto FAY-GEE for months haha! 26 Reply 6 replies @craigsherman5520 @craigsherman5520 4 years ago Lots of good information, but, with all due respect, the doctor is no poster child for autophagy. He seems in need of some fasting himself.. 11 Reply 4 replies @bhartithakkar100 @bhartithakkar100 4 years ago 👍 I am very hungry at morning 7 to 8 o’clock. What to do? Have to eat at 10:30🙁 Reply Naomi Whittel · 7 replies @kauigirl808 @kauigirl808 2 years ago I eat between 7am- 2pm. Reply @eugenepelle4790 @eugenepelle4790 10 months ago Is Authophagy Fasting is done without water also Reply @Neeko_Z @Neeko_Z 2 years ago 🧐 wait, correct me if wrong... according to him Autophagy is cool, but with a person with cancer it’s not unless with chemo?... Reply 1 reply @robertsmyk4102 @robertsmyk4102 2 years ago Yeast cells undergo autophagy when they are starved of nutrition but human cells are always receiving nutrition from body fat even when fasting so why say that autophagy occurs when fasting? Reply @a.aaliev4033 @a.aaliev4033 9 months ago So, I don’t think that fasting for day or interminably not activate autophagy) in your body present mechanisms which before “self-eating” balance your level of amino acids and other biomolecules, and really fantastic thought that autophagy is saving mechanism 😃😃😃😃for your cells, this process out of your view, Reply @bhaskarswadi9132 @bhaskarswadi9132 3 years ago Can you fast 3 times week ? CAN YOU FAST IN YOU EIGHTIES AND EARLY NINETIES.. 1 Reply Naomi Whittel · 1 reply @pakodasingh @pakodasingh 7 months ago (edited) And still doctors take all credit and believe they did it.....if doctors be little honest to their jobs rest leave to autophagy at least maximum health problems will be solved... they all care about money and ways to keep mafia going on. Reply @wojo6567 @wojo6567 3 years ago (edited) He went to Penn State I went to the State Pen. Nice info & helpful. 13 Reply 3 replies @lee16 @lee16 3 years ago Why there is nobody talk about how to survived on prolong fasting. When your body getting lack of vitamins. You are in risk of lowering electrolytes, even if you use right water. What we should do.!? Reply 7 replies @ErickHernandez-pu5np @ErickHernandez-pu5np 3 years ago Maybe im just an idiot but i seen half the video and still have no clue what apa....is or whats the point of it how to do it etc. I just saw this word in a fasting video and thought this would explain it. Can anyone suggest any other videos to understand all this and how it relates to fasting. Sorry. I am not trolling just ignorant and new to intermittent fasting. Been doing the warrior diet (4hr window) for about 1 month now but think im hitting a plateau so looking for ways to break that. 1 Reply Naomi Whittel · 1 reply @sir_Reall @sir_Reall 1 year ago Somehow I was expecting a leaner doctor 🤔 Reply @yehmiyah @yehmiyah 3 years ago wonderful :) HalLeLuYAH 4 Reply @lindamarsh6711 @lindamarsh6711 2 years ago Haven’t got a clue except that the cell eats itself. Reply @bhaskarswadi9132 @bhaskarswadi9132 3 years ago Dear DR.WM DUNNE, PLEASE TELL ME WHETHER INTERMITANT FASTING DELAYS APPOSTOSIS IN THE HEART MUSLE FIBERS. 13NOV Reply @JennWest-Liberty @JennWest-Liberty 3 years ago So if I take amino acids while fasting I won’t get into autophagy? 1 Reply 3 replies @changchang8690 @changchang8690 3 years ago What’s his protocol 1 Reply @danbujor5991 @danbujor5991 2 years ago (edited) You said the cell produces amino acids. So the proper name for this WHOLE THING should be : CELL RENEWAL or SELF FEEDING.. 1 Reply 1 reply @RJay121 @RJay121 1 year ago Under the needless catagory of Just Sayin. Anybody else notice after dozens of longevity talking heads on Youtube, with few exceptions most don't look much younger for it? Just Sayin. Reply @floridalife-livinginflorid6882 @floridalife-livinginflorid6882 1 year ago (edited) dump the simple sugar. Dr Fung kidney specialist studies autophagy. Reply @lahoucine66 @lahoucine66 4 years ago 🌷🤲Quran 2:184🌴🍃 "and it is better for you that you fast , if you only knew. "🌴🤲🍃 14 Naomi Whittel Reply 9 replies @lizardfirefighter110 @lizardfirefighter110 3 years ago See Dr David Sinclair for slowing the aging process! 7 Reply @drdavidphd869 @drdavidphd869 4 years ago This guy is really confusing and contrary to other sources. Most talk about activate the autophagy in the case of cancer; he says shut it down. How does that make sense. His explanation isn't clear. 24 Reply 6 replies @BBEETTYYful @BBEETTYYful 2 years ago NoT true dear dr!!!! Reply @kunjikorans @kunjikorans 3 years ago Where can I buy 100% pure Organic WILL POWER? 29 Reply 16 replies @zenaidapalafox2122 @zenaidapalafox2122 1 year ago Have you heard of Kangen Water ? Reply @ritamix33 @ritamix33 1 year ago She sounds like she’s trying to emulate an American accent. She almost does, but I can hear another accent behind that. Where is she from? Reply @CaitlinBurt @CaitlinBurt 2 years ago How is this everything you need to know Reply @elmafudd9703 @elmafudd9703 1 year ago Could the interviewer have placed a little more effort into the research before this happened. If you dumb everything down than everyone's dumb. 1 Reply @chrisferrell6159 @chrisferrell6159 2 years ago Starving people should be the healthiest but the dye. Anorexia should be a plus but it destroys ones health 1 Reply 1 reply @sweetmsroslyn @sweetmsroslyn 3 years ago The first question is; what is it? Reply 2 replies @infiniteg7852 @infiniteg7852 2 years ago (edited) You look like you can be his daughter. You look like him Reply @kienchin5total @kienchin5total 2 months ago You are taking credit for autophagy lol Reply @stephenwism @stephenwism 3 years ago This dude looks good. Reply 1 reply @rishicabrera4484 @rishicabrera4484 2 years ago 🤔 interesting.... Reply @pawelkostulak9955 @pawelkostulak9955 11 months ago Can't get through this because of the interviewer- cut own on wows, nodding and facial expressions straight out of daytime talk show Reply @jardinbotanique9490 @jardinbotanique9490 4 years ago the dude is holding up the 3 sixes!! Reply @goodwong5389 @goodwong5389 3 years ago He just can not say it right. Why would I want to turn-off Autophagy so that I let chemo kill cancer?? He wants to keep chemo as a constent factor in fighting cancer??? Is that why he says it wrong?? Why not keep autophagy Turned-on and turn off chemo to let Autopahy kill cancer, meanwhile applying intermittent fasting. Which is the right way to fight cancer 4 Reply 1 reply @joec1132 @joec1132 1 year ago Can you please wait until your guest finishes speaking before you interrupt him to say what you think? We want to hear your guest speak not you. Reply @dannydaniels8352 @dannydaniels8352 3 years ago This contradicts every other source on the subject. 6 Reply 2 replies @waffle_chair9269 @waffle_chair9269 2 weeks ago Who is this guy? What’s his background etc? Why no bio? Reply @patrick707100 @patrick707100 1 year ago This makes Autophagy far too complicated. Autophagy occurres when we FAST. The simple answer is FASTING..Intermittent fasting is one half way step but a seven to ten day water fast is far better, Keep it simple stupid. -KISS KISS KISS. FASTING> Reply @robin7222 @robin7222 3 years ago You just wasted my time. When does autophagy kick in? 8 Reply 9 replies @sircassian5568 @sircassian5568 2 years ago (edited) NAOMI all the science is in Islam.....RAMADAN does 2 types of autophagy. Cell autophagy and sins autophagy in the soul... Reply @yanostropicalparadise755 @yanostropicalparadise755 2 years ago a proper human diet is the solution to almost all human conditions and illnesses. a human diet is animal foods and fats only everything ells is harmfull. Reply @saxgirlhornboy6458 @saxgirlhornboy6458 1 year ago Way too much Naomi. Distracts from guests' presentations. Reply @akanecortich8197 @akanecortich8197 4 years ago Autophagy burning the furniture in the house for energy.\? 1 Reply 2 replies @michaelrivers4363 @michaelrivers4363 3 years ago #snake diet 1 Reply @SM-ol9nb @SM-ol9nb 2 years ago Oh my god I am so sick of that stupid house cleaning analogy it’s terrible cant you come up with a better one Reply @dunnbrandon @dunnbrandon 4 years ago Not very convincing when the dr looks overweight himself 2 Reply Naomi Whittel · 1 reply @garyfletcher844 @garyfletcher844 2 years ago I remember back in the day when the brothers said Give Me Some Skin. Little did i know that that has become literal. Reply @garyfletcher844 @garyfletcher844 2 years ago Why not take it to bone level with Sarcophagy. 1 Reply